MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 SUPERFAMILY SSF47831 218 325 6.67E-24 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 444 730 2.5E-93 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Pfam PF05524 PEP-utilising enzyme, N-terminal 188 310 7.9E-20 T 13-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Gene3D G3DSA:1.10.274.10 206 333 1.4E-54 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 SUPERFAMILY SSF51621 444 731 2.62E-94 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 SUPERFAMILY SSF55781 7 168 1.55E-32 T 13-10-2018 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 188 755 5.8E-134 T 13-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Pfam PF00391 PEP-utilising enzyme, mobile domain 340 412 2.5E-20 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 SUPERFAMILY SSF52009 292 418 5.76E-28 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 SMART SM00065 26 173 1.0E-23 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Gene3D G3DSA:3.20.20.60 420 764 2.5E-102 T 13-10-2018 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Gene3D G3DSA:3.30.450.40 7 173 1.4E-49 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Gene3D G3DSA:3.50.30.10 189 419 1.4E-54 T 13-10-2018 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 Pfam PF01590 GAF domain 27 163 8.1E-19 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 637 652 3.7E-23 T 13-10-2018 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 480 499 3.7E-23 T 13-10-2018 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 654 669 3.7E-23 T 13-10-2018 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 690 702 3.7E-23 T 13-10-2018 MADE_1003445 5cd7db32b4de15cfd520b442906dfe97 772 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 637 655 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MADE_1004035 70e82ab1b57f041e56232f793f13e99d 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 125 1.8E-37 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MADE_1004035 70e82ab1b57f041e56232f793f13e99d 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 119 1.0E-21 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MADE_1004035 70e82ab1b57f041e56232f793f13e99d 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 125 22.818 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MADE_1004035 70e82ab1b57f041e56232f793f13e99d 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 125 4.9E-30 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MADE_1004035 70e82ab1b57f041e56232f793f13e99d 126 Gene3D G3DSA:3.90.470.20 2 125 8.5E-38 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MADE_1004035 70e82ab1b57f041e56232f793f13e99d 126 SUPERFAMILY SSF56214 3 124 4.84E-30 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 MADE_1004035 70e82ab1b57f041e56232f793f13e99d 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 95 4.0E-22 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Gene3D G3DSA:3.30.830.10 261 455 1.1E-28 T 13-10-2018 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Pfam PF05193 Peptidase M16 inactive domain 205 376 2.7E-24 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Pfam PF05193 Peptidase M16 inactive domain 648 824 2.6E-24 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Gene3D G3DSA:3.30.830.10 483 693 1.3E-51 T 13-10-2018 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Gene3D G3DSA:3.30.830.10 705 900 2.2E-34 T 13-10-2018 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Gene3D G3DSA:3.30.830.10 33 255 8.3E-65 T 13-10-2018 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Pfam PF00675 Insulinase (Peptidase family M16) 49 175 1.1E-15 T 13-10-2018 IPR011765 Peptidase M16, N-terminal MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 Pfam PF00675 Insulinase (Peptidase family M16) 494 615 4.8E-17 T 13-10-2018 IPR011765 Peptidase M16, N-terminal MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 SUPERFAMILY SSF63411 477 687 4.83E-51 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 SUPERFAMILY SSF63411 36 244 2.2E-53 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 SUPERFAMILY SSF63411 710 902 1.32E-29 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1012055 38f133ec6a77cdbb8211efb014ae5acb 917 SUPERFAMILY SSF63411 268 450 1.23E-23 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1002365 9d46ae9d7ef24fdba172aaf15b39cc37 172 Pfam PF10688 Bacterial inner membrane protein 7 165 1.9E-22 T 13-10-2018 IPR019629 Uncharacterised protein family HI1736/YgjV MADE_1005445 aadc10791c5529ec5ed30cfffd5561ee 195 Pfam PF01713 Smr domain 100 179 1.6E-14 T 13-10-2018 IPR002625 Smr domain MADE_1005445 aadc10791c5529ec5ed30cfffd5561ee 195 SUPERFAMILY SSF160443 98 179 7.32E-8 T 13-10-2018 IPR036063 Smr domain superfamily MADE_1005445 aadc10791c5529ec5ed30cfffd5561ee 195 Gene3D G3DSA:3.30.1370.110 39 185 5.1E-36 T 13-10-2018 MADE_1016415 216380b398dc700469abce22433aa586 840 SUPERFAMILY SSF52743 101 436 6.94E-71 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MADE_1016415 216380b398dc700469abce22433aa586 840 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 386 396 - T 13-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MADE_1016415 216380b398dc700469abce22433aa586 840 PRINTS PR00723 Subtilisin serine protease family (S8) signature 385 401 3.1E-19 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1016415 216380b398dc700469abce22433aa586 840 PRINTS PR00723 Subtilisin serine protease family (S8) signature 157 176 3.1E-19 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1016415 216380b398dc700469abce22433aa586 840 PRINTS PR00723 Subtilisin serine protease family (S8) signature 217 230 3.1E-19 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1016415 216380b398dc700469abce22433aa586 840 Pfam PF01483 Proprotein convertase P-domain 591 669 7.2E-19 T 13-10-2018 IPR002884 P domain GO:0004252|GO:0006508 MADE_1016415 216380b398dc700469abce22433aa586 840 Gene3D G3DSA:2.60.40.10 676 761 5.4E-27 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1016415 216380b398dc700469abce22433aa586 840 Gene3D G3DSA:2.60.120.260 564 675 2.7E-17 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1016415 216380b398dc700469abce22433aa586 840 SUPERFAMILY SSF49299 679 759 2.09E-21 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1016415 216380b398dc700469abce22433aa586 840 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 221 231 - T 13-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MADE_1016415 216380b398dc700469abce22433aa586 840 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 162 173 - T 13-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MADE_1016415 216380b398dc700469abce22433aa586 840 Pfam PF00082 Subtilase family 158 422 1.8E-41 T 13-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MADE_1016415 216380b398dc700469abce22433aa586 840 Gene3D G3DSA:3.40.50.200 117 452 2.7E-107 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MADE_1016415 216380b398dc700469abce22433aa586 840 SUPERFAMILY SSF49785 578 673 2.21E-22 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1016415 216380b398dc700469abce22433aa586 840 SMART SM00089 682 760 1.9E-20 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1016415 216380b398dc700469abce22433aa586 840 Pfam PF00801 PKD domain 689 747 2.2E-12 T 13-10-2018 IPR000601 PKD domain MADE_1016980 31f0f478fc0f39a09261e868319b42de 473 Pfam PF00209 Sodium:neurotransmitter symporter family 144 463 2.5E-24 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1016980 31f0f478fc0f39a09261e868319b42de 473 Pfam PF00209 Sodium:neurotransmitter symporter family 5 124 1.2E-24 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1016980 31f0f478fc0f39a09261e868319b42de 473 SUPERFAMILY SSF161070 5 463 1.96E-111 T 13-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 MADE_1016980 31f0f478fc0f39a09261e868319b42de 473 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 307 326 1.2E-5 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1016980 31f0f478fc0f39a09261e868319b42de 473 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 1.2E-5 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1016980 31f0f478fc0f39a09261e868319b42de 473 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 89 115 1.2E-5 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1019640 1a3bb62b338dae9786b7a07a722cbc0f 104 Gene3D G3DSA:3.30.70.120 1 103 1.0E-35 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MADE_1019640 1a3bb62b338dae9786b7a07a722cbc0f 104 SUPERFAMILY SSF54913 2 102 5.93E-33 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MADE_1019640 1a3bb62b338dae9786b7a07a722cbc0f 104 Pfam PF03091 CutA1 divalent ion tolerance protein 5 100 3.0E-34 T 13-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 MADE_1011940 1bf94048a6da59bbec286094a1b780aa 76 SUPERFAMILY SSF47598 1 45 6.45E-12 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1011940 1bf94048a6da59bbec286094a1b780aa 76 Gene3D G3DSA:1.10.8.1250 10 76 1.8E-9 T 13-10-2018 IPR038296 Antitoxin ParD superfamily MADE_1011940 1bf94048a6da59bbec286094a1b780aa 76 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 6 72 1.4E-6 T 13-10-2018 IPR022789 Antitoxin ParD MADE_1011940 1bf94048a6da59bbec286094a1b780aa 76 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 66 1.5E-15 T 13-10-2018 IPR022789 Antitoxin ParD MADE_1007530 a49dd6ac9532bd2ecb7c580625b6c87f 281 Gene3D G3DSA:3.90.550.10 2 226 4.0E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1007530 a49dd6ac9532bd2ecb7c580625b6c87f 281 Pfam PF13641 Glycosyltransferase like family 2 20 219 5.4E-9 T 13-10-2018 MADE_1007530 a49dd6ac9532bd2ecb7c580625b6c87f 281 SUPERFAMILY SSF53448 7 235 9.34E-24 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1003545 5cca578b929ddbe648d7e8fe53d29e56 462 Pfam PF02321 Outer membrane efflux protein 24 216 1.3E-31 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1003545 5cca578b929ddbe648d7e8fe53d29e56 462 Pfam PF02321 Outer membrane efflux protein 241 439 7.4E-35 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1003545 5cca578b929ddbe648d7e8fe53d29e56 462 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 451 9.2E-119 T 13-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 MADE_1003545 5cca578b929ddbe648d7e8fe53d29e56 462 Gene3D G3DSA:1.20.1600.10 21 460 9.3E-131 T 13-10-2018 MADE_1003545 5cca578b929ddbe648d7e8fe53d29e56 462 SUPERFAMILY SSF56954 1 441 4.19E-98 T 13-10-2018 MADE_1007670 715517029d01f0e52e9484a997c20fd2 284 Pfam PF00793 DAHP synthetase I family 16 273 3.5E-66 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MADE_1007670 715517029d01f0e52e9484a997c20fd2 284 Gene3D G3DSA:3.20.20.70 2 282 3.3E-97 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1007670 715517029d01f0e52e9484a997c20fd2 284 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 15 276 49.257 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MADE_1007670 715517029d01f0e52e9484a997c20fd2 284 SUPERFAMILY SSF51569 5 277 2.56E-101 T 13-10-2018 MADE_1007670 715517029d01f0e52e9484a997c20fd2 284 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 20 274 3.1E-114 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MADE_1003080 8bef780dbc2b6364386f8a23dfa97cd7 98 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 90 8.2E-9 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1003080 8bef780dbc2b6364386f8a23dfa97cd7 98 Gene3D G3DSA:3.30.2310.20 1 91 4.6E-9 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 Pfam PF00158 Sigma-54 interaction domain 207 371 2.3E-59 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 Pfam PF00989 PAS fold 81 129 7.3E-6 T 13-10-2018 IPR013767 PAS fold GO:0006355 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 418 427 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 Gene3D G3DSA:3.30.450.20 82 190 1.8E-23 T 13-10-2018 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 Gene3D G3DSA:1.10.8.60 378 452 5.0E-22 T 13-10-2018 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 Gene3D G3DSA:3.40.50.300 193 376 1.3E-59 T 13-10-2018 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 SUPERFAMILY SSF55785 77 130 1.17E-6 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 Gene3D G3DSA:3.30.70.260 1 80 2.1E-26 T 13-10-2018 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 SMART SM00382 226 369 6.5E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 465 513 2.7E-28 T 13-10-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 SUPERFAMILY SSF46689 456 512 7.77E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 SUPERFAMILY SSF55021 2 68 8.39E-6 T 13-10-2018 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 230 243 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 Gene3D G3DSA:1.10.10.60 454 513 2.1E-27 T 13-10-2018 MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 SMART SM00091 80 146 2.9E-4 T 13-10-2018 IPR000014 PAS domain MADE_1006180 98ef923ef2fdce054b378e10c57994cf 518 SUPERFAMILY SSF52540 206 447 7.1E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009040 44562b777cc642a3d18be8de936a9297 828 SMART SM00729 418 669 6.6E-7 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1009040 44562b777cc642a3d18be8de936a9297 828 Pfam PF11842 Domain of unknown function (DUF3362) 636 786 5.8E-39 T 13-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal MADE_1009040 44562b777cc642a3d18be8de936a9297 828 Pfam PF04055 Radical SAM superfamily 422 625 1.1E-19 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1009040 44562b777cc642a3d18be8de936a9297 828 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 64 688 49.666 T 13-10-2018 IPR022946 Uncharacterised protein family UPF0313 MADE_1009040 44562b777cc642a3d18be8de936a9297 828 SUPERFAMILY SSF102114 402 655 8.11E-12 T 13-10-2018 MADE_1009040 44562b777cc642a3d18be8de936a9297 828 Gene3D G3DSA:3.80.30.20 417 686 3.9E-16 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MADE_1009040 44562b777cc642a3d18be8de936a9297 828 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 64 686 3.2E-262 T 13-10-2018 IPR022946 Uncharacterised protein family UPF0313 MADE_1009040 44562b777cc642a3d18be8de936a9297 828 Pfam PF08497 Radical SAM N-terminal 64 421 4.5E-145 T 13-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal MADE_1009040 44562b777cc642a3d18be8de936a9297 828 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 422 442 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MADE_000001023440 1c4fef83b67501c22d14c1e1662764ba 234 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 22 229 2.1E-62 T 13-10-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated MADE_000001023440 1c4fef83b67501c22d14c1e1662764ba 234 SUPERFAMILY SSF56300 43 191 8.78E-12 T 13-10-2018 MADE_000001023440 1c4fef83b67501c22d14c1e1662764ba 234 PIRSF PIRSF000887 22 233 3.8E-43 T 13-10-2018 IPR024173 Phosphoesterase, MJ0037 MADE_000001023440 1c4fef83b67501c22d14c1e1662764ba 234 Gene3D G3DSA:3.60.21.10 41 142 1.1E-7 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like MADE_000001023440 1c4fef83b67501c22d14c1e1662764ba 234 Pfam PF00149 Calcineurin-like phosphoesterase 43 150 8.9E-6 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MADE_1004595 9fa6da5c7067f80292e8c341f6f9208d 239 SUPERFAMILY SSF52540 38 177 6.69E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004595 9fa6da5c7067f80292e8c341f6f9208d 239 Gene3D G3DSA:3.40.50.300 10 238 4.9E-34 T 13-10-2018 MADE_1004595 9fa6da5c7067f80292e8c341f6f9208d 239 Pfam PF06414 Zeta toxin 26 212 4.4E-42 T 13-10-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1047 1.2E-226 T 13-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 PIRSF PIRSF000980 1 1114 2.5E-239 T 13-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 SUPERFAMILY SSF52980 827 1063 8.58E-16 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 Gene3D G3DSA:3.40.50.10930 4 293 4.1E-86 T 13-10-2018 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 SUPERFAMILY SSF52540 2 336 2.66E-84 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 2 781 2.5E-239 T 13-10-2018 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 Gene3D G3DSA:3.40.50.300 326 782 4.4E-145 T 13-10-2018 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 Gene3D G3DSA:1.10.10.160 80 187 4.1E-86 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1095 17.25 T 13-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 SUPERFAMILY SSF52540 348 782 1.06E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013635 31521dc6637810b2c851710d71c8cb00 1206 Gene3D G3DSA:1.10.486.10 443 653 4.4E-145 T 13-10-2018 MADE_1007325 054da7e97e137213d4d50d221030de86 540 SMART SM00448 9 125 4.3E-12 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007325 054da7e97e137213d4d50d221030de86 540 SMART SM00028 168 201 26.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1007325 054da7e97e137213d4d50d221030de86 540 SMART SM00028 390 423 200.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1007325 054da7e97e137213d4d50d221030de86 540 SMART SM00028 235 268 56.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1007325 054da7e97e137213d4d50d221030de86 540 SMART SM00028 448 481 4.7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1007325 054da7e97e137213d4d50d221030de86 540 Pfam PF00072 Response regulator receiver domain 12 125 5.5E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007325 054da7e97e137213d4d50d221030de86 540 Gene3D G3DSA:1.25.40.10 335 528 1.8E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1007325 054da7e97e137213d4d50d221030de86 540 Gene3D G3DSA:1.25.40.10 137 300 1.9E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1007325 054da7e97e137213d4d50d221030de86 540 Gene3D G3DSA:3.40.50.2300 4 136 1.0E-17 T 13-10-2018 MADE_1007325 054da7e97e137213d4d50d221030de86 540 SUPERFAMILY SSF48452 359 495 7.82E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1007325 054da7e97e137213d4d50d221030de86 540 SUPERFAMILY SSF52172 8 143 2.56E-18 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1007325 054da7e97e137213d4d50d221030de86 540 SUPERFAMILY SSF48452 140 285 1.43E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003510 c327329b9418b42302b61ea6db981d4e 465 SUPERFAMILY SSF88723 10 159 1.11E-14 T 13-10-2018 IPR029060 PIN-like domain superfamily MADE_1003510 c327329b9418b42302b61ea6db981d4e 465 Pfam PF13638 PIN domain 12 157 8.4E-35 T 13-10-2018 IPR002716 PIN domain MADE_1003510 c327329b9418b42302b61ea6db981d4e 465 Gene3D G3DSA:3.40.50.300 253 463 3.1E-64 T 13-10-2018 MADE_1003510 c327329b9418b42302b61ea6db981d4e 465 SMART SM00670 10 148 5.7E-8 T 13-10-2018 IPR002716 PIN domain MADE_1003510 c327329b9418b42302b61ea6db981d4e 465 Gene3D G3DSA:3.40.50.1010 6 162 1.2E-27 T 13-10-2018 MADE_1003510 c327329b9418b42302b61ea6db981d4e 465 Pfam PF02562 PhoH-like protein 255 459 1.7E-53 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 MADE_1003510 c327329b9418b42302b61ea6db981d4e 465 SUPERFAMILY SSF52540 254 444 8.16E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002110 7902b0650cc66048be71eba65e517848 561 Gene3D G3DSA:3.50.50.60 456 556 9.0E-12 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1002110 7902b0650cc66048be71eba65e517848 561 Pfam PF05199 GMC oxidoreductase 425 548 9.1E-20 T 13-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MADE_1002110 7902b0650cc66048be71eba65e517848 561 Pfam PF00732 GMC oxidoreductase 71 312 7.2E-15 T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_1002110 7902b0650cc66048be71eba65e517848 561 Gene3D G3DSA:3.50.50.60 237 341 3.1E-8 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1002110 7902b0650cc66048be71eba65e517848 561 SUPERFAMILY SSF54373 350 497 7.06E-54 T 13-10-2018 MADE_1002110 7902b0650cc66048be71eba65e517848 561 SUPERFAMILY SSF51905 1 557 5.9E-66 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1002110 7902b0650cc66048be71eba65e517848 561 Gene3D G3DSA:3.50.50.60 1 170 9.6E-22 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1013775 4b798fb60a46654085e9e00c1c2cd070 250 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 13-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MADE_1013775 4b798fb60a46654085e9e00c1c2cd070 250 SUPERFAMILY SSF52402 1 242 2.58E-84 T 13-10-2018 MADE_1013775 4b798fb60a46654085e9e00c1c2cd070 250 Gene3D G3DSA:3.40.50.620 1 248 4.0E-87 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1013775 4b798fb60a46654085e9e00c1c2cd070 250 SMART SM00893 23 211 9.2E-66 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MADE_1013775 4b798fb60a46654085e9e00c1c2cd070 250 PIRSF PIRSF000090 1 249 2.7E-83 T 13-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 MADE_1013775 4b798fb60a46654085e9e00c1c2cd070 250 Pfam PF01012 Electron transfer flavoprotein domain 31 206 6.9E-46 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 SMART SM00347 24 124 2.6E-21 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 8.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 8.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 8.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 8.4E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 Pfam PF01047 MarR family 31 89 4.1E-15 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 Gene3D G3DSA:1.10.10.10 1 142 1.7E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009180 d13560636e17bb49be4f1ee8c3d4659b 158 SUPERFAMILY SSF46785 4 141 4.1E-31 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1012365 2179f06cd765549bee079254c37b0460 191 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 185 8.6E-14 T 13-10-2018 IPR003111 Lon, substrate-binding domain MADE_1012365 2179f06cd765549bee079254c37b0460 191 Gene3D G3DSA:1.10.4060.10 114 191 2.7E-5 T 13-10-2018 MADE_1012365 2179f06cd765549bee079254c37b0460 191 SUPERFAMILY SSF88697 5 190 5.47E-47 T 13-10-2018 IPR015947 PUA-like superfamily MADE_1012365 2179f06cd765549bee079254c37b0460 191 Gene3D G3DSA:2.30.130.40 3 113 1.1E-28 T 13-10-2018 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 584 2.5E-256 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 SUPERFAMILY SSF55261 288 419 1.64E-48 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 Gene3D G3DSA:3.30.930.10 116 579 5.2E-195 T 13-10-2018 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 SUPERFAMILY SSF50249 1 105 7.81E-34 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 Pfam PF02938 GAD domain 307 406 1.0E-31 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 Gene3D G3DSA:3.30.1360.30 271 420 5.2E-195 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 5.2E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 516 530 5.2E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 5.2E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 PRINTS PR01042 Aspartyl-tRNA synthetase signature 472 488 5.2E-26 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 5.6E-17 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 Gene3D G3DSA:2.40.50.140 1 106 5.2E-34 T 13-10-2018 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 582 33.482 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 Pfam PF00152 tRNA synthetases class II (D, K and N) 117 556 2.9E-108 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021160 82ade9758bd58e06338c9b160837b818 586 SUPERFAMILY SSF55681 108 580 5.9E-106 T 13-10-2018 MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 Gene3D G3DSA:3.40.50.720 15 334 2.2E-129 T 13-10-2018 MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 336 9.0E-28 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 SUPERFAMILY SSF51735 121 317 4.06E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 Gene3D G3DSA:3.40.50.720 121 316 2.2E-129 T 13-10-2018 MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 SUPERFAMILY SSF52283 15 153 4.35E-36 T 13-10-2018 MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 129 316 1.1E-54 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 166 193 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MADE_1009625 693f1973e5e1b9172d989f8bd9156b59 341 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 242 258 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MADE_1004390 517b45d6b4145e3839b353148db40b4d 727 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 445 721 2.0E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1004390 517b45d6b4145e3839b353148db40b4d 727 Gene3D G3DSA:1.10.3720.10 530 723 1.4E-24 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1004390 517b45d6b4145e3839b353148db40b4d 727 Gene3D G3DSA:1.10.3720.10 421 524 1.3E-5 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1004390 517b45d6b4145e3839b353148db40b4d 727 SUPERFAMILY SSF161098 409 522 4.45E-10 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1004390 517b45d6b4145e3839b353148db40b4d 727 SUPERFAMILY SSF161098 538 713 3.4E-21 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1011785 270ef2e75eb77ef9ac3d5710b76ccf54 295 PIRSF PIRSF015558 1 284 7.2E-91 T 13-10-2018 IPR016634 WYL domain protein, s026 type MADE_1011785 270ef2e75eb77ef9ac3d5710b76ccf54 295 Pfam PF13280 WYL domain 119 201 2.3E-11 T 13-10-2018 IPR026881 WYL domain MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 4 410 61.725 T 13-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 Pfam PF00970 Oxidoreductase FAD-binding domain 205 269 8.6E-10 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 Gene3D G3DSA:2.40.30.10 129 267 1.2E-49 T 13-10-2018 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 SUPERFAMILY SSF52343 262 406 3.67E-37 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 317 328 7.2E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 219 7.2E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 305 314 7.2E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 279 298 7.2E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 376 384 7.2E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 Gene3D G3DSA:3.40.50.80 278 396 3.1E-33 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 6 410 5.3E-223 T 13-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 Pfam PF00175 Oxidoreductase NAD-binding domain 280 388 3.7E-18 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 SUPERFAMILY SSF54292 38 125 5.54E-21 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 Gene3D G3DSA:3.10.20.30 37 128 1.8E-30 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 SUPERFAMILY SSF63380 108 273 8.06E-34 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 40 117 2.0E-9 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MADE_000001022960 6994a048bff717fcedef97b5efd5b34f 410 PIRSF PIRSF000044 1 410 3.7E-216 T 13-10-2018 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 MADE_1006370 2093e219ae61fff58d2dc02656210a40 357 Pfam PF13533 Biotin-lipoyl like 47 94 6.3E-13 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_1006370 2093e219ae61fff58d2dc02656210a40 357 SUPERFAMILY SSF111369 45 172 9.15E-15 T 13-10-2018 MADE_1006370 2093e219ae61fff58d2dc02656210a40 357 Gene3D G3DSA:2.40.30.170 216 336 2.3E-17 T 13-10-2018 MADE_1006370 2093e219ae61fff58d2dc02656210a40 357 SUPERFAMILY SSF111369 172 233 8.76E-7 T 13-10-2018 MADE_1006370 2093e219ae61fff58d2dc02656210a40 357 Gene3D G3DSA:2.40.50.100 46 80 2.4E-10 T 13-10-2018 MADE_1006370 2093e219ae61fff58d2dc02656210a40 357 Gene3D G3DSA:1.10.287.470 81 104 2.4E-10 T 13-10-2018 MADE_1006370 2093e219ae61fff58d2dc02656210a40 357 Gene3D G3DSA:1.10.287.470 105 199 3.7E-8 T 13-10-2018 MADE_1000835 8890fd8ff26776c2231a52671e11481f 199 Gene3D G3DSA:3.30.40.60 94 198 1.5E-5 T 13-10-2018 MADE_1000835 8890fd8ff26776c2231a52671e11481f 199 SMART SM00507 134 194 2.3E-9 T 13-10-2018 IPR003615 HNH nuclease MADE_1000835 8890fd8ff26776c2231a52671e11481f 199 Pfam PF01844 HNH endonuclease 147 198 9.0E-15 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 MADE_1013065 e99b8adc80e5e1b94e2198fa04fd7b03 731 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 727 0.0 T 13-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MADE_1013065 e99b8adc80e5e1b94e2198fa04fd7b03 731 Gene3D G3DSA:3.20.20.360 10 585 3.3E-256 T 13-10-2018 MADE_1013065 e99b8adc80e5e1b94e2198fa04fd7b03 731 Pfam PF01274 Malate synthase 18 702 8.2E-159 T 13-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MADE_1013065 e99b8adc80e5e1b94e2198fa04fd7b03 731 Gene3D G3DSA:1.20.1220.12 588 731 2.9E-69 T 13-10-2018 MADE_1013065 e99b8adc80e5e1b94e2198fa04fd7b03 731 Hamap MF_00641 Malate synthase G [glcB]. 1 731 364.628 T 13-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MADE_1013065 e99b8adc80e5e1b94e2198fa04fd7b03 731 SUPERFAMILY SSF51645 3 727 3.66E-281 T 13-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MADE_1013065 e99b8adc80e5e1b94e2198fa04fd7b03 731 Gene3D G3DSA:2.170.170.11 133 262 3.3E-256 T 13-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 9 572 59.0 T 13-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 433 559 0.064 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Gene3D G3DSA:3.30.413.10 428 569 7.7E-35 T 13-10-2018 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 18 560 1.0E-280 T 13-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Gene3D G3DSA:3.90.480.20 15 418 2.1E-83 T 13-10-2018 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 354 418 2.7E-15 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 78 138 2.7E-14 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Gene3D G3DSA:3.30.413.10 140 349 2.1E-83 T 13-10-2018 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 PRINTS PR00397 Sirohaem Fe-binding site signature 431 449 6.0E-8 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 PRINTS PR00397 Sirohaem Fe-binding site signature 479 497 6.0E-8 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 SUPERFAMILY SSF55124 347 424 1.46E-22 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 SUPERFAMILY SSF56014 148 345 3.01E-56 T 13-10-2018 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 SUPERFAMILY SSF56014 429 563 5.1E-33 T 13-10-2018 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 172 330 7.3E-46 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 SUPERFAMILY SSF55124 13 144 1.47E-26 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016735 509709d0a547971f51ed75208e5fe15c 573 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 479 495 - T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_000001021060 9302c11c5896eb39374ec34dda290099 253 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 253 113.478 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MADE_000001021060 9302c11c5896eb39374ec34dda290099 253 SUPERFAMILY SSF75217 6 246 2.62E-101 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_000001021060 9302c11c5896eb39374ec34dda290099 253 Gene3D G3DSA:3.40.1280.10 2 164 5.3E-68 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_000001021060 9302c11c5896eb39374ec34dda290099 253 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 6 238 8.5E-102 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MADE_000001021060 9302c11c5896eb39374ec34dda290099 253 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 27 225 1.4E-66 T 13-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MADE_000001021060 9302c11c5896eb39374ec34dda290099 253 PIRSF PIRSF000386 6 252 1.2E-100 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MADE_000001021060 9302c11c5896eb39374ec34dda290099 253 Gene3D G3DSA:1.10.1270.20 165 253 3.1E-34 T 13-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 731 1.6E-121 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 SUPERFAMILY SSF48168 10 221 2.35E-73 T 13-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 Gene3D G3DSA:3.20.70.20 78 741 2.4E-157 T 13-10-2018 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 141 219 1.3E-12 T 13-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 1.5E-37 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 1.5E-37 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 1.5E-37 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 1.5E-37 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 1.5E-37 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 1.5E-37 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 Pfam PF03477 ATP cone domain 6 92 2.9E-17 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 SUPERFAMILY SSF51998 222 741 7.94E-169 T 13-10-2018 MADE_1010770 74f7b130d8bf56f353817ff1abfedbc4 773 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 1.8E-177 T 13-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 Pfam PF14561 Tetratricopeptide repeat 202 289 1.4E-23 T 13-10-2018 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 PRINTS PR00421 Thioredoxin family signature 41 50 6.7E-5 T 13-10-2018 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 PRINTS PR00421 Thioredoxin family signature 81 92 6.7E-5 T 13-10-2018 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 PRINTS PR00421 Thioredoxin family signature 33 41 6.7E-5 T 13-10-2018 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 Pfam PF00085 Thioredoxin 13 115 5.3E-27 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 TIGRFAM TIGR01068 thioredoxin: thioredoxin 17 115 1.4E-30 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 SUPERFAMILY SSF52833 10 119 7.79E-36 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 Gene3D G3DSA:1.25.40.10 119 203 7.8E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 Pfam PF14559 Tetratricopeptide repeat 131 197 6.6E-18 T 13-10-2018 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 SUPERFAMILY SSF48452 113 251 2.14E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 Gene3D G3DSA:1.25.40.10 204 289 1.5E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 ProSitePatterns PS00194 Thioredoxin family active site. 34 52 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_1002915 f30f694d68f78beae284e1f49d642fd8 289 Gene3D G3DSA:3.40.30.10 5 118 8.4E-33 T 13-10-2018 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 SUPERFAMILY SSF52833 2 102 3.02E-21 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 Gene3D G3DSA:3.50.50.60 217 507 8.7E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 SUPERFAMILY SSF52833 106 197 6.41E-19 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 Gene3D G3DSA:3.40.30.80 1 201 1.1E-60 T 13-10-2018 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 Gene3D G3DSA:3.50.50.60 326 449 8.7E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 279 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 443 464 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 315 323 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 249 264 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 477 495 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 217 239 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 404 420 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 337 349 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 352 376 5.4E-61 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 441 457 1.8E-37 T 13-10-2018 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 374 1.8E-37 T 13-10-2018 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 314 332 1.8E-37 T 13-10-2018 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 237 1.8E-37 T 13-10-2018 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 467 489 1.8E-37 T 13-10-2018 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 SUPERFAMILY SSF51905 217 513 2.77E-49 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 344 364 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 PIRSF PIRSF000238 1 520 2.2E-212 T 13-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 217 497 4.5E-44 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 Pfam PF13192 Thioredoxin domain 122 199 1.8E-12 T 13-10-2018 IPR012336 Thioredoxin-like fold MADE_1009000 b5c6b9f6739dcb69ed6ece089f204e84 529 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 516 4.1E-230 T 13-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 MADE_1013070 d27ddfc0d0f721a803202b9d1cfedde7 294 SUPERFAMILY SSF52151 23 283 6.8E-37 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MADE_1013070 d27ddfc0d0f721a803202b9d1cfedde7 294 Gene3D G3DSA:3.40.1090.10 117 284 4.2E-16 T 13-10-2018 MADE_1013070 d27ddfc0d0f721a803202b9d1cfedde7 294 Gene3D G3DSA:3.40.1090.10 6 116 2.9E-22 T 13-10-2018 MADE_1013070 d27ddfc0d0f721a803202b9d1cfedde7 294 Pfam PF01734 Patatin-like phospholipase 24 181 1.7E-24 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:3.30.70.1440 667 863 0.0 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82693 670 854 9.94E-30 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:3.30.70.1430 38 815 0.0 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:3.30.70.1320 132 331 0.0 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:3.30.2090.10 719 807 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:1.20.1640.10 512 1020 0.0 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82866 295 496 7.46E-48 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82693 38 132 3.4E-26 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82714 182 271 2.22E-24 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82714 720 807 3.01E-22 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Pfam PF00873 AcrB/AcrD/AcrF family 1 1023 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:3.30.70.1430 566 666 0.0 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1032 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 335 358 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 362 383 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 444 467 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.2E-105 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:1.20.1640.10 8 511 0.0 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82693 564 667 5.23E-27 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82693 137 329 1.73E-23 T 13-10-2018 MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 Gene3D G3DSA:3.30.2090.10 178 274 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000900 27ad995770befd5ee9ca0b2fce2b02a5 1033 SUPERFAMILY SSF82866 829 1023 3.14E-45 T 13-10-2018 MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 227 260 2.3E-5 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 114 149 1.3E-8 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 150 184 2.0E-10 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 13 334 2.3E-109 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 28 94 5.1E-20 T 13-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 Gene3D G3DSA:2.160.10.10 105 314 1.6E-61 T 13-10-2018 MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 14 331 34.646 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 Gene3D G3DSA:3.40.1390.10 3 101 5.1E-30 T 13-10-2018 MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 111 139 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MADE_1012465 63a09cd1b2ad0a3d1e5feb3f937541d0 342 SUPERFAMILY SSF51161 39 323 8.58E-83 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Gene3D G3DSA:1.10.150.20 356 424 2.0E-26 T 13-10-2018 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 368 417 3.3E-21 T 13-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 443 491 1.0E-13 T 13-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Pfam PF14520 Helix-hairpin-helix domain 435 489 7.5E-5 T 13-10-2018 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Pfam PF13184 NusA-like KH domain 233 300 3.1E-27 T 13-10-2018 IPR025249 KH domain, NusA-like GO:0003723 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 SUPERFAMILY SSF50249 135 202 1.65E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 SUPERFAMILY SSF47794 357 419 3.45E-16 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Pfam PF00575 S1 RNA binding domain 135 197 1.2E-5 T 13-10-2018 IPR003029 S1 domain GO:0003676 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 SUPERFAMILY SSF54814 203 281 2.09E-29 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Gene3D G3DSA:3.30.300.20 202 280 8.1E-31 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 345 3.8E-123 T 13-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 SMART SM00316 136 203 7.6E-10 T 13-10-2018 IPR022967 RNA-binding domain, S1 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Gene3D G3DSA:2.40.50.140 138 201 4.7E-18 T 13-10-2018 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 SUPERFAMILY SSF69705 1 128 2.22E-36 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 413 28.577 T 13-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Gene3D G3DSA:3.30.300.20 281 348 2.8E-24 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 SUPERFAMILY SSF54814 282 346 6.98E-15 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Gene3D G3DSA:1.10.150.20 434 493 2.4E-20 T 13-10-2018 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Pfam PF08529 NusA N-terminal domain 4 127 5.7E-33 T 13-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 Gene3D G3DSA:3.30.1480.10 1 132 8.8E-40 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 MADE_1008915 ed03ad48e495a88d54d8dfb03d1ff6e2 498 SUPERFAMILY SSF47794 432 494 2.2E-15 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 SMART SM00304 209 263 7.8E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 Gene3D G3DSA:3.30.450.20 34 185 2.5E-50 T 13-10-2018 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 Gene3D G3DSA:1.10.287.950 209 540 4.0E-72 T 13-10-2018 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 Pfam PF00672 HAMP domain 210 257 5.8E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 SMART SM01049 35 126 7.7E-28 T 13-10-2018 IPR033480 Single Cache domain 2 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 SUPERFAMILY SSF58104 231 540 1.57E-69 T 13-10-2018 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 366 503 1.8E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 Pfam PF08269 Cache domain 47 182 2.0E-38 T 13-10-2018 IPR004010 Double Cache domain 2 MADE_1003400 1201c3987ce83534d9f8f6a12f4d87a4 540 SMART SM00283 278 539 4.5E-66 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 Pfam PF00005 ABC transporter 285 429 1.1E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 SUPERFAMILY SSF52540 4 231 1.77E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 Gene3D G3DSA:3.40.50.300 257 509 7.0E-64 T 13-10-2018 MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 Gene3D G3DSA:3.40.50.300 1 243 3.0E-59 T 13-10-2018 MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 Pfam PF00005 ABC transporter 21 167 2.7E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 SMART SM00382 294 485 2.6E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 SMART SM00382 29 217 3.5E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1000635 e64d7b9abaf696a62e7bc25561c9e3d2 627 SUPERFAMILY SSF52540 269 490 7.77E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006015 1916c3a29d85911626490971ae093fe1 271 Gene3D G3DSA:2.40.50.180 143 256 4.8E-6 T 13-10-2018 MADE_1006015 1916c3a29d85911626490971ae093fe1 271 SUPERFAMILY SSF50341 125 260 1.02E-16 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1006015 1916c3a29d85911626490971ae093fe1 271 Gene3D G3DSA:2.30.30.40 129 251 4.8E-6 T 13-10-2018 MADE_1006015 1916c3a29d85911626490971ae093fe1 271 SMART SM00260 115 257 6.8E-5 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1006015 1916c3a29d85911626490971ae093fe1 271 Pfam PF01584 CheW-like domain 126 259 1.4E-14 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1006015 1916c3a29d85911626490971ae093fe1 271 PIRSF PIRSF020479 3 270 1.5E-81 T 13-10-2018 IPR014506 Uncharacterised conserved protein UCP020479, signal transduction CheW-like MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 SMART SM01185 69 123 2.1E-24 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 Gene3D G3DSA:2.40.50.140 66 127 5.1E-28 T 13-10-2018 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 SUPERFAMILY SSF50104 2 63 2.31E-20 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 Pfam PF09285 Elongation factor P, C-terminal 131 186 6.7E-26 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 SUPERFAMILY SSF50249 130 187 1.08E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 Hamap MF_00141 Elongation factor P [efp]. 3 187 48.562 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 SMART SM00841 131 186 2.3E-33 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 Gene3D G3DSA:2.30.30.30 1 64 1.2E-26 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 Gene3D G3DSA:2.40.50.140 130 188 2.3E-28 T 13-10-2018 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 SUPERFAMILY SSF50249 69 128 7.28E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 1.0E-24 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 123 5.5E-22 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 PIRSF PIRSF005901 2 188 4.0E-65 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 13-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MADE_1003610 1fd49e4d8fca7a17305c0306cf285a7c 189 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 1.2E-78 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 MADE_1008490 effceb8f73f6482ff478f767455b50db 347 Pfam PF01112 Asparaginase 40 345 1.2E-111 T 13-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 MADE_1008490 effceb8f73f6482ff478f767455b50db 347 Gene3D G3DSA:3.60.20.30 213 347 8.6E-48 T 13-10-2018 MADE_1008490 effceb8f73f6482ff478f767455b50db 347 SUPERFAMILY SSF56235 39 344 2.32E-92 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1000165 d889f1117a10f4753510604f21819138 176 PIRSF PIRSF029681 1 176 3.6E-45 T 13-10-2018 IPR018550 Lipid A 3-O-deacylase-related MADE_1000165 d889f1117a10f4753510604f21819138 176 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 40 175 3.1E-30 T 13-10-2018 IPR018550 Lipid A 3-O-deacylase-related MADE_1000165 d889f1117a10f4753510604f21819138 176 Gene3D G3DSA:2.40.160.20 36 175 8.1E-36 T 13-10-2018 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 13 338 3.1E-138 T 13-10-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 SMART SM00858 287 345 7.7E-6 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 Pfam PF03102 NeuB family 35 271 2.9E-81 T 13-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 SUPERFAMILY SSF51569 1 297 1.71E-84 T 13-10-2018 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 Gene3D G3DSA:3.90.1210.10 293 347 3.2E-15 T 13-10-2018 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 Gene3D G3DSA:3.20.20.70 1 292 3.6E-95 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 Pfam PF08666 SAF domain 288 344 3.9E-8 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MADE_1005820 491badbd8cc0c15660c65b213e091061 347 SUPERFAMILY SSF51269 283 343 1.83E-15 T 13-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 PIRSF PIRSF000185 22 447 2.6E-108 T 13-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 SUPERFAMILY SSF53223 10 196 9.92E-66 T 13-10-2018 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 Gene3D G3DSA:1.10.285.10 7 384 6.8E-149 T 13-10-2018 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 13-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 SUPERFAMILY SSF51735 202 447 7.54E-66 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 Gene3D G3DSA:1.10.285.10 395 447 1.4E-7 T 13-10-2018 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 Gene3D G3DSA:3.40.50.720 209 373 6.8E-149 T 13-10-2018 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 5.4E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 5.4E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 5.4E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 5.4E-30 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 446 7.7E-73 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 58 185 6.5E-50 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 SMART SM00839 204 446 1.1E-66 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_000001021930 93edf802023dafad2408c0cc0c837c69 447 Gene3D G3DSA:3.40.50.10860 55 190 6.8E-149 T 13-10-2018 MADE_1014910 ce2488c085a09fd4c7c1bde72b847766 218 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 214 3.7E-70 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MADE_1014910 ce2488c085a09fd4c7c1bde72b847766 218 Gene3D G3DSA:3.40.50.1360 7 206 5.0E-77 T 13-10-2018 MADE_1014910 ce2488c085a09fd4c7c1bde72b847766 218 SUPERFAMILY SSF100950 1 146 3.02E-45 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1014910 ce2488c085a09fd4c7c1bde72b847766 218 Gene3D G3DSA:3.30.70.260 125 196 5.0E-77 T 13-10-2018 MADE_1014910 ce2488c085a09fd4c7c1bde72b847766 218 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 5.6E-58 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MADE_1014910 ce2488c085a09fd4c7c1bde72b847766 218 SUPERFAMILY SSF75445 127 198 2.62E-24 T 13-10-2018 MADE_1014910 ce2488c085a09fd4c7c1bde72b847766 218 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 33.689 T 13-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 MADE_1007385 546f71ca0bad7b0069e47528344559af 256 SUPERFAMILY SSF53098 46 217 3.19E-39 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1007385 546f71ca0bad7b0069e47528344559af 256 Gene3D G3DSA:3.30.420.10 44 230 6.8E-9 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1007385 546f71ca0bad7b0069e47528344559af 256 Pfam PF00665 Integrase core domain 46 161 7.3E-18 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1009290 546f71ca0bad7b0069e47528344559af 256 SUPERFAMILY SSF53098 46 217 3.19E-39 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1009290 546f71ca0bad7b0069e47528344559af 256 Gene3D G3DSA:3.30.420.10 44 230 6.8E-9 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1009290 546f71ca0bad7b0069e47528344559af 256 Pfam PF00665 Integrase core domain 46 161 7.3E-18 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1009300 546f71ca0bad7b0069e47528344559af 256 SUPERFAMILY SSF53098 46 217 3.19E-39 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1009300 546f71ca0bad7b0069e47528344559af 256 Gene3D G3DSA:3.30.420.10 44 230 6.8E-9 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1009300 546f71ca0bad7b0069e47528344559af 256 Pfam PF00665 Integrase core domain 46 161 7.3E-18 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1007040 546f71ca0bad7b0069e47528344559af 256 SUPERFAMILY SSF53098 46 217 3.19E-39 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1007040 546f71ca0bad7b0069e47528344559af 256 Gene3D G3DSA:3.30.420.10 44 230 6.8E-9 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1007040 546f71ca0bad7b0069e47528344559af 256 Pfam PF00665 Integrase core domain 46 161 7.3E-18 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_000001021795 e1223433edb77af22e1df49dc31e3854 87 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 1 87 23.049 T 13-10-2018 IPR007454 Uncharacterised protein family UPF0250 MADE_000001021795 e1223433edb77af22e1df49dc31e3854 87 Gene3D G3DSA:3.30.70.260 1 87 1.1E-28 T 13-10-2018 MADE_000001021795 e1223433edb77af22e1df49dc31e3854 87 Pfam PF04359 Protein of unknown function (DUF493) 7 87 1.8E-26 T 13-10-2018 IPR007454 Uncharacterised protein family UPF0250 MADE_000001021795 e1223433edb77af22e1df49dc31e3854 87 SUPERFAMILY SSF117991 1 87 2.22E-28 T 13-10-2018 IPR027471 YbeD-like domain superfamily MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 234 357 2.4E-8 T 13-10-2018 IPR000014 PAS domain MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 SMART SM00267 350 516 4.2E-47 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 Gene3D G3DSA:3.30.450.20 220 358 2.0E-11 T 13-10-2018 MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 SUPERFAMILY SSF55073 366 511 1.41E-41 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 358 512 2.9E-40 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 SUPERFAMILY SSF55785 222 348 5.02E-10 T 13-10-2018 IPR035965 PAS domain superfamily MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 Pfam PF00990 Diguanylate cyclase, GGDEF domain 361 512 4.7E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021285 c69cd29818bd6b12ad43a4f7dd6b1b91 531 Gene3D G3DSA:3.30.70.270 359 516 5.4E-47 T 13-10-2018 MADE_1007880 ac06e009a5b56221cc7722329378edf4 212 Pfam PF02525 Flavodoxin-like fold 14 183 5.4E-43 T 13-10-2018 IPR003680 Flavodoxin-like fold MADE_1007880 ac06e009a5b56221cc7722329378edf4 212 Gene3D G3DSA:3.40.50.360 10 191 5.8E-49 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1007880 ac06e009a5b56221cc7722329378edf4 212 SUPERFAMILY SSF52218 14 189 3.1E-45 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1007920 d54818417636c2f2a3c3b526ca3640a4 110 Gene3D G3DSA:2.60.40.180 1 110 1.5E-33 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MADE_1007920 d54818417636c2f2a3c3b526ca3640a4 110 ProSitePatterns PS00769 Transthyretin signature 2. 93 105 - T 13-10-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MADE_1007920 d54818417636c2f2a3c3b526ca3640a4 110 PRINTS PR00189 Transthyretin signature 3 23 2.5E-5 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MADE_1007920 d54818417636c2f2a3c3b526ca3640a4 110 PRINTS PR00189 Transthyretin signature 88 110 2.5E-5 T 13-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MADE_1007920 d54818417636c2f2a3c3b526ca3640a4 110 Pfam PF00576 HIUase/Transthyretin family 4 109 4.7E-31 T 13-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MADE_1007920 d54818417636c2f2a3c3b526ca3640a4 110 SUPERFAMILY SSF49472 1 110 1.96E-35 T 13-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 MADE_1007920 d54818417636c2f2a3c3b526ca3640a4 110 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 110 9.3E-33 T 13-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MADE_000001023555 93a39888a6042034a85c65e288b1f8c0 317 Gene3D G3DSA:1.10.20.140 124 195 1.4E-106 T 13-10-2018 MADE_000001023555 93a39888a6042034a85c65e288b1f8c0 317 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 17 313 30.07 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MADE_000001023555 93a39888a6042034a85c65e288b1f8c0 317 Pfam PF01715 IPP transferase 51 296 4.7E-86 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MADE_000001023555 93a39888a6042034a85c65e288b1f8c0 317 Gene3D G3DSA:3.40.50.300 21 301 1.4E-106 T 13-10-2018 MADE_000001023555 93a39888a6042034a85c65e288b1f8c0 317 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 17 302 1.6E-107 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 MADE_000001023555 93a39888a6042034a85c65e288b1f8c0 317 SUPERFAMILY SSF52540 17 160 7.51E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Pfam PF00072 Response regulator receiver domain 653 763 3.2E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Pfam PF00989 PAS fold 131 247 1.3E-10 T 13-10-2018 IPR013767 PAS fold GO:0006355 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SMART SM00448 651 763 1.5E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Gene3D G3DSA:3.30.450.20 127 250 3.1E-20 T 13-10-2018 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SMART SM00086 76 118 12.0 T 13-10-2018 IPR001610 PAC motif MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SMART SM00086 208 250 0.13 T 13-10-2018 IPR001610 PAC motif MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Gene3D G3DSA:3.30.565.10 336 496 3.7E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SMART SM00387 382 493 4.1E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Pfam PF13426 PAS domain 15 117 3.0E-9 T 13-10-2018 IPR000014 PAS domain MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Gene3D G3DSA:3.40.50.2300 648 771 5.1E-30 T 13-10-2018 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 490 7.5E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Gene3D G3DSA:3.30.450.20 8 126 4.6E-17 T 13-10-2018 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SMART SM00091 130 197 2.8E-9 T 13-10-2018 IPR000014 PAS domain MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SMART SM00091 5 70 64.0 T 13-10-2018 IPR000014 PAS domain MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 432 6.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 490 6.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 471 6.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 446 6.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SMART SM00388 270 335 2.0E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SUPERFAMILY SSF47384 255 336 4.12E-21 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SUPERFAMILY SSF55874 324 495 1.7E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Pfam PF00512 His Kinase A (phospho-acceptor) domain 270 334 6.0E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 257 3.3E-14 T 13-10-2018 IPR000014 PAS domain MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 124 3.4E-8 T 13-10-2018 IPR000014 PAS domain MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SUPERFAMILY SSF52172 651 775 5.55E-31 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SUPERFAMILY SSF55785 115 248 5.06E-22 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 SUPERFAMILY SSF55785 15 120 9.6E-14 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1003910 61ccce40e649bf4cc9c1e6e29945cd82 962 Gene3D G3DSA:1.10.287.130 251 333 3.9E-26 T 13-10-2018 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Pfam PF01103 Surface antigen 452 825 4.5E-79 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Gene3D G3DSA:3.10.20.310 351 429 1.3E-19 T 13-10-2018 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 28 825 9.6E-262 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Pfam PF07244 Surface antigen variable number repeat 96 176 3.3E-9 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Pfam PF07244 Surface antigen variable number repeat 270 348 6.5E-12 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Pfam PF07244 Surface antigen variable number repeat 180 267 5.4E-14 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Pfam PF07244 Surface antigen variable number repeat 351 425 2.9E-10 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Gene3D G3DSA:2.40.160.50 430 825 1.0E-112 T 13-10-2018 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Gene3D G3DSA:3.10.20.310 179 268 4.2E-21 T 13-10-2018 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Gene3D G3DSA:3.10.20.310 269 350 7.2E-17 T 13-10-2018 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Gene3D G3DSA:3.10.20.310 96 176 3.9E-14 T 13-10-2018 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 PIRSF PIRSF006076 1 825 8.8E-233 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 1 825 24.214 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 MADE_1005360 6ad0b9505ed899009d288368b2a16bdd 825 Gene3D G3DSA:3.10.20.310 22 95 1.2E-16 T 13-10-2018 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Pfam PF03764 Elongation factor G, domain IV 476 594 3.8E-43 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 SUPERFAMILY SSF52540 3 278 2.85E-99 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Pfam PF14492 Elongation Factor G, domain II 401 475 5.5E-30 T 13-10-2018 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Gene3D G3DSA:3.30.70.870 403 480 2.4E-27 T 13-10-2018 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Pfam PF03144 Elongation factor Tu domain 2 321 388 3.4E-16 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Pfam PF00679 Elongation factor G C-terminus 598 683 9.2E-28 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 SMART SM00889 477 595 3.0E-60 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Pfam PF00009 Elongation factor Tu GTP binding domain 7 278 3.0E-60 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Hamap MF_00054_B Elongation factor G [fusA]. 3 688 102.593 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 SUPERFAMILY SSF50447 261 399 5.3E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Gene3D G3DSA:2.40.30.10 291 402 3.7E-37 T 13-10-2018 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 689 5.9E-295 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 175 8.5E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Gene3D G3DSA:3.30.230.10 481 684 2.3E-82 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 SUPERFAMILY SSF54980 600 691 2.41E-28 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 PRINTS PR00315 GTP-binding elongation factor signature 127 136 3.7E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 PRINTS PR00315 GTP-binding elongation factor signature 9 22 3.7E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 PRINTS PR00315 GTP-binding elongation factor signature 75 85 3.7E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 PRINTS PR00315 GTP-binding elongation factor signature 55 63 3.7E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Gene3D G3DSA:3.40.50.300 1 290 4.5E-100 T 13-10-2018 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 SUPERFAMILY SSF54211 476 596 6.57E-40 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 Gene3D G3DSA:3.30.70.240 601 671 2.3E-82 T 13-10-2018 MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 SUPERFAMILY SSF54980 401 478 3.09E-21 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1007700 bf3ac52f07498ced4010fe3772520b24 695 SMART SM00838 597 684 2.6E-43 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 Pfam PF00813 FliP family 50 243 1.8E-80 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 50 247 1.2E-82 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 224 236 - T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 237 247 6.7E-20 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 118 132 6.7E-20 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 146 158 6.7E-20 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 106 118 6.7E-20 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 169 181 6.7E-20 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 46 55 6.7E-20 T 13-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 176 191 - T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 221 246 2.3E-66 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 197 218 2.3E-66 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 176 196 2.3E-66 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 67 87 2.3E-66 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 48 67 2.3E-66 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1005950 ef9b3d1791a7806ef8300a6b9c2f87bf 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 87 106 2.3E-66 T 13-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 MADE_1011670 907768e196bbae8d49886b47df853de6 732 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 135 721 3.5E-182 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MADE_1011670 907768e196bbae8d49886b47df853de6 732 Gene3D G3DSA:3.20.20.80 177 722 3.4E-117 T 13-10-2018 MADE_1011670 907768e196bbae8d49886b47df853de6 732 Pfam PF02446 4-alpha-glucanotransferase 184 703 9.5E-124 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 MADE_1011670 907768e196bbae8d49886b47df853de6 732 SUPERFAMILY SSF51445 178 718 4.29E-143 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1006335 732f3ce163896f5d6dc41531cb1a5383 298 Gene3D G3DSA:3.40.190.10 166 267 8.9E-55 T 13-10-2018 MADE_1006335 732f3ce163896f5d6dc41531cb1a5383 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 4.5E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006335 732f3ce163896f5d6dc41531cb1a5383 298 Gene3D G3DSA:3.40.190.10 94 292 8.9E-55 T 13-10-2018 MADE_1006335 732f3ce163896f5d6dc41531cb1a5383 298 SUPERFAMILY SSF53850 93 296 7.29E-38 T 13-10-2018 MADE_1006335 732f3ce163896f5d6dc41531cb1a5383 298 Pfam PF03466 LysR substrate binding domain 91 295 3.5E-38 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1006335 732f3ce163896f5d6dc41531cb1a5383 298 Gene3D G3DSA:1.10.10.10 6 93 6.2E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006335 732f3ce163896f5d6dc41531cb1a5383 298 SUPERFAMILY SSF46785 7 87 3.02E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SMART SM00387 397 513 4.3E-37 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 510 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 466 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 491 6.7E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Gene3D G3DSA:3.30.565.10 352 514 4.6E-50 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SMART SM00086 230 272 0.0013 T 13-10-2018 IPR001610 PAC motif MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SMART SM00448 528 640 4.7E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Gene3D G3DSA:1.10.287.970 6 92 5.8E-13 T 13-10-2018 IPR027460 Aerobic respiration control sensor protein ArcB, transmembrane domain superfamily MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Pfam PF01627 Hpt domain 692 767 3.1E-13 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SUPERFAMILY SSF47226 668 779 2.49E-26 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Pfam PF00072 Response regulator receiver domain 530 639 1.1E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SMART SM00388 285 350 5.4E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 158 278 9.2E-17 T 13-10-2018 IPR000014 PAS domain MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Gene3D G3DSA:1.10.287.130 275 351 1.4E-18 T 13-10-2018 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Pfam PF08448 PAS fold 165 274 1.7E-17 T 13-10-2018 IPR013656 PAS fold-4 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Gene3D G3DSA:3.40.50.2300 515 643 9.4E-32 T 13-10-2018 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Pfam PF00512 His Kinase A (phospho-acceptor) domain 286 348 2.8E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SMART SM00091 158 224 6.3E-7 T 13-10-2018 IPR000014 PAS domain MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SUPERFAMILY SSF47384 273 351 3.92E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Gene3D G3DSA:3.30.450.20 145 274 6.9E-23 T 13-10-2018 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Gene3D G3DSA:1.20.120.160 661 782 5.5E-29 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SUPERFAMILY SSF55785 144 270 2.97E-22 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 512 1.3E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SUPERFAMILY SSF52172 526 645 3.13E-29 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 PIRSF PIRSF003182 8 783 1.6E-282 T 13-10-2018 IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB GO:0000155|GO:0000160|GO:0004673|GO:0016021 MADE_1015770 4c7e12d895a7537d63ecf5cc8c785f57 784 SUPERFAMILY SSF55874 339 514 2.75E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018505 535e46184a8082abe06cdf4d7f483539 360 Gene3D G3DSA:3.10.580.10 174 327 7.1E-35 T 13-10-2018 MADE_1018505 535e46184a8082abe06cdf4d7f483539 360 SUPERFAMILY SSF54631 184 318 3.28E-25 T 13-10-2018 MADE_1018505 535e46184a8082abe06cdf4d7f483539 360 Pfam PF00571 CBS domain 266 315 2.1E-8 T 13-10-2018 IPR000644 CBS domain MADE_1018505 535e46184a8082abe06cdf4d7f483539 360 Pfam PF00571 CBS domain 203 252 0.0055 T 13-10-2018 IPR000644 CBS domain MADE_1018505 535e46184a8082abe06cdf4d7f483539 360 SMART SM00116 203 253 37.0 T 13-10-2018 IPR000644 CBS domain MADE_1018505 535e46184a8082abe06cdf4d7f483539 360 SMART SM00116 267 315 0.012 T 13-10-2018 IPR000644 CBS domain MADE_1018505 535e46184a8082abe06cdf4d7f483539 360 Pfam PF01595 Domain of unknown function DUF21 8 177 5.3E-29 T 13-10-2018 IPR002550 CNNM, transmembrane domain MADE_000001023425 6c8f012fc06274e2f95aaed53d992131 235 Gene3D G3DSA:3.40.50.720 4 235 5.6E-46 T 13-10-2018 MADE_000001023425 6c8f012fc06274e2f95aaed53d992131 235 SUPERFAMILY SSF51735 5 234 2.36E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001023425 6c8f012fc06274e2f95aaed53d992131 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 6.7E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001023425 6c8f012fc06274e2f95aaed53d992131 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 6.7E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001023425 6c8f012fc06274e2f95aaed53d992131 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.7E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001023425 6c8f012fc06274e2f95aaed53d992131 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 233 2.1E-26 T 13-10-2018 MADE_000001023425 6c8f012fc06274e2f95aaed53d992131 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 25 746 40.688 T 13-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Gene3D G3DSA:3.40.50.12320 205 377 1.4E-32 T 13-10-2018 MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Pfam PF05127 Helicase 209 386 1.2E-38 T 13-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Gene3D G3DSA:3.40.50.11040 14 197 2.8E-19 T 13-10-2018 MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 SUPERFAMILY SSF55729 420 575 1.32E-11 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Gene3D G3DSA:3.40.630.30 388 593 1.5E-54 T 13-10-2018 MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 SUPERFAMILY SSF52540 181 333 1.45E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Pfam PF13718 GNAT acetyltransferase 2 543 592 1.7E-6 T 13-10-2018 IPR000182 GNAT domain MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Pfam PF13718 GNAT acetyltransferase 2 427 542 1.8E-12 T 13-10-2018 IPR000182 GNAT domain MADE_1006285 d428e124aae0096182006d9a1f6552bb 759 Pfam PF08351 Domain of unknown function (DUF1726) 70 155 2.4E-7 T 13-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 Pfam PF02796 Helix-turn-helix domain of resolvase 141 180 7.1E-6 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 Pfam PF00239 Resolvase, N terminal domain 6 138 2.4E-45 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 SUPERFAMILY SSF53041 5 138 9.94E-45 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 Gene3D G3DSA:3.40.50.1390 5 127 1.4E-45 T 13-10-2018 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 SUPERFAMILY SSF46689 141 182 3.58E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 Gene3D G3DSA:1.10.10.60 139 181 1.1E-13 T 13-10-2018 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 ProSitePatterns PS00398 Site-specific recombinases signature 2. 58 70 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MADE_1011880 d32cd51983dffb1608040f2f7ce5b9fb 194 SMART SM00857 5 139 2.5E-57 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MADE_1001545 874f891940e799f8917d73a7df3cd7ae 454 Pfam PF02321 Outer membrane efflux protein 256 438 6.1E-16 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1001545 874f891940e799f8917d73a7df3cd7ae 454 Pfam PF02321 Outer membrane efflux protein 30 209 2.6E-12 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1001545 874f891940e799f8917d73a7df3cd7ae 454 SUPERFAMILY SSF56954 4 438 7.85E-52 T 13-10-2018 MADE_1001545 874f891940e799f8917d73a7df3cd7ae 454 Gene3D G3DSA:1.20.1600.10 23 440 1.3E-49 T 13-10-2018 MADE_1016010 782eed82d521b9b63f15244056bfd5ad 241 SUPERFAMILY SSF69593 22 234 5.36E-40 T 13-10-2018 MADE_1016010 782eed82d521b9b63f15244056bfd5ad 241 Pfam PF01553 Acyltransferase 64 179 9.7E-27 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1016010 782eed82d521b9b63f15244056bfd5ad 241 SMART SM00563 67 182 6.2E-32 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1016010 782eed82d521b9b63f15244056bfd5ad 241 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 178 1.1E-37 T 13-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 MADE_1009955 a3df4d272fc9f0bd6cb1d62202e045a0 302 SUPERFAMILY SSF53850 89 296 3.08E-38 T 13-10-2018 MADE_1009955 a3df4d272fc9f0bd6cb1d62202e045a0 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.3E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009955 a3df4d272fc9f0bd6cb1d62202e045a0 302 Pfam PF03466 LysR substrate binding domain 89 293 1.5E-36 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1009955 a3df4d272fc9f0bd6cb1d62202e045a0 302 Gene3D G3DSA:1.10.10.10 1 87 6.6E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009955 a3df4d272fc9f0bd6cb1d62202e045a0 302 SUPERFAMILY SSF46785 3 111 2.04E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1009955 a3df4d272fc9f0bd6cb1d62202e045a0 302 Gene3D G3DSA:3.40.190.290 90 291 5.1E-51 T 13-10-2018 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 Pfam PF00248 Aldo/keto reductase family 14 262 3.9E-50 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 PIRSF PIRSF000097 114 277 1.3E-32 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 PIRSF PIRSF000097 4 125 7.4E-40 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 SUPERFAMILY SSF51430 7 272 1.14E-82 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 Gene3D G3DSA:3.20.20.100 3 274 5.1E-89 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 PRINTS PR00069 Aldo-keto reductase signature 126 143 8.6E-48 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 PRINTS PR00069 Aldo-keto reductase signature 198 222 8.6E-48 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 PRINTS PR00069 Aldo-keto reductase signature 93 111 8.6E-48 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 PRINTS PR00069 Aldo-keto reductase signature 33 57 8.6E-48 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006355 521df2e8a937aea50053e65f342ab3d9 278 PRINTS PR00069 Aldo-keto reductase signature 161 190 8.6E-48 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Gene3D G3DSA:3.40.50.2300 3 136 3.0E-24 T 13-10-2018 MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 SUPERFAMILY SSF55785 262 366 4.0E-11 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Pfam PF00072 Response regulator receiver domain 9 119 5.3E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 SMART SM00052 534 781 5.7E-58 T 13-10-2018 IPR001633 EAL domain MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 256 365 1.4E-7 T 13-10-2018 IPR000014 PAS domain MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Gene3D G3DSA:3.30.70.270 363 535 3.8E-46 T 13-10-2018 MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Pfam PF00563 EAL domain 542 776 7.4E-56 T 13-10-2018 IPR001633 EAL domain MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Pfam PF13426 PAS domain 262 357 1.0E-5 T 13-10-2018 IPR000014 PAS domain MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 SUPERFAMILY SSF55073 374 526 9.42E-40 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 366 523 1.6E-39 T 13-10-2018 IPR000160 GGDEF domain MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Pfam PF00990 Diguanylate cyclase, GGDEF domain 369 519 9.5E-35 T 13-10-2018 IPR000160 GGDEF domain MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 SMART SM00267 358 524 3.7E-48 T 13-10-2018 IPR000160 GGDEF domain MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Gene3D G3DSA:3.30.450.20 246 360 5.0E-12 T 13-10-2018 MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 SMART SM00448 7 119 3.3E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 Gene3D G3DSA:3.20.20.450 536 793 1.4E-66 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 SUPERFAMILY SSF52172 6 136 5.27E-25 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1013270 c12ccad04da10ac9f1f307155699dfbc 798 SUPERFAMILY SSF141868 540 788 2.88E-64 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001021375 d7e7663c1b9c19750cfdfc531925b167 123 Gene3D G3DSA:3.40.50.720 1 122 2.2E-11 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Gene3D G3DSA:3.30.413.10 631 805 3.2E-33 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Gene3D G3DSA:3.50.50.60 11 284 8.0E-85 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1003695 4c758b150a38332419cbd27560df0f72 849 SUPERFAMILY SSF51905 5 191 1.16E-44 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Pfam PF04324 BFD-like [2Fe-2S] binding domain 423 470 3.8E-10 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 632 754 2.0E-18 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Gene3D G3DSA:3.50.50.60 112 247 8.0E-85 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 288 1.0E-51 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 5.8E-17 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 5.8E-17 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 5.8E-17 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 5.8E-17 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 5.8E-17 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00397 Sirohaem Fe-binding site signature 678 696 6.5E-7 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00397 Sirohaem Fe-binding site signature 635 653 6.5E-7 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 10 800 0.0 T 13-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Gene3D G3DSA:1.10.10.1100 422 476 3.3E-11 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 678 694 - T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 559 620 7.8E-12 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 5.2E-8 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 5.2E-8 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 5.2E-8 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 5.2E-8 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 PIRSF PIRSF037149 1 834 0.0 T 13-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 SUPERFAMILY SSF56014 632 807 8.37E-52 T 13-10-2018 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 SUPERFAMILY SSF55124 501 640 1.28E-27 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1003695 4c758b150a38332419cbd27560df0f72 849 SUPERFAMILY SSF51905 151 310 3.52E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Gene3D G3DSA:2.40.50.100 103 205 2.9E-20 T 13-10-2018 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Pfam PF00364 Biotin-requiring enzyme 4 76 3.9E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Pfam PF00364 Biotin-requiring enzyme 111 182 8.5E-18 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Gene3D G3DSA:2.40.50.100 1 80 3.2E-21 T 13-10-2018 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 SUPERFAMILY SSF51230 1 95 3.8E-25 T 13-10-2018 IPR011053 Single hybrid motif MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Gene3D G3DSA:4.10.320.10 206 248 1.4E-20 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 SUPERFAMILY SSF52777 273 502 8.9E-89 T 13-10-2018 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 272 501 5.4E-81 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 134 163 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Gene3D G3DSA:3.30.559.10 271 503 1.0E-96 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 Pfam PF02817 e3 binding domain 210 243 5.9E-16 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 111 503 2.3E-181 T 13-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 SUPERFAMILY SSF47005 204 248 4.58E-13 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MADE_1009500 1fafc04131de246e490e6a64a57935e7 503 SUPERFAMILY SSF51230 110 201 7.33E-23 T 13-10-2018 IPR011053 Single hybrid motif MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Gene3D G3DSA:1.10.287.130 388 493 5.4E-26 T 13-10-2018 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Pfam PF01627 Hpt domain 951 1029 1.1E-13 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SMART SM00388 430 495 9.1E-23 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Pfam PF07696 7TMR-DISM extracellular 2 42 169 5.2E-24 T 13-10-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 596 3.9E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 635 3.9E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 610 3.9E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 PRINTS PR00344 Bacterial sensor protein C-terminal signature 641 654 3.9E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Gene3D G3DSA:3.40.50.2300 793 924 6.5E-36 T 13-10-2018 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Pfam PF00072 Response regulator receiver domain 805 916 1.1E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Gene3D G3DSA:2.60.40.2380 38 171 3.2E-15 T 13-10-2018 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SUPERFAMILY SSF47384 417 496 1.79E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SMART SM00387 541 657 4.2E-34 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Gene3D G3DSA:3.30.565.10 494 661 7.6E-46 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SMART SM00448 803 916 1.1E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SUPERFAMILY SSF55874 484 655 3.8E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SUPERFAMILY SSF52172 801 921 2.85E-34 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 541 656 2.0E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Gene3D G3DSA:1.20.120.160 931 1037 4.1E-28 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Pfam PF00512 His Kinase A (phospho-acceptor) domain 431 495 1.0E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 Pfam PF07695 7TM diverse intracellular signalling 182 386 6.7E-41 T 13-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SUPERFAMILY SSF47226 899 1031 7.07E-23 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1002475 e5ddbe7b5671c00cd0ecd16f95449e86 1042 SMART SM00073 942 1036 5.3E-9 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1020270 4318a4524b897ddcef3643c432d5ebd0 86 Pfam PF01206 Sulfurtransferase TusA 15 83 3.1E-22 T 13-10-2018 IPR001455 TusA-like domain MADE_1020270 4318a4524b897ddcef3643c432d5ebd0 86 SUPERFAMILY SSF64307 8 83 1.31E-23 T 13-10-2018 IPR036868 TusA-like domain superfamily MADE_1020270 4318a4524b897ddcef3643c432d5ebd0 86 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 16 40 - T 13-10-2018 IPR001455 TusA-like domain MADE_1020270 4318a4524b897ddcef3643c432d5ebd0 86 Gene3D G3DSA:3.30.110.40 5 85 1.1E-27 T 13-10-2018 IPR036868 TusA-like domain superfamily MADE_1020270 4318a4524b897ddcef3643c432d5ebd0 86 Hamap MF_00413 Sulfur carrier protein TusA [tusA]. 7 85 26.995 T 13-10-2018 IPR022931 Sulfur carrier protein TusA GO:0002143|GO:0097163 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 3 626 0.0 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 ProSitePatterns PS00177 DNA topoisomerase II signature. 417 425 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 629 46.863 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 559 621 4.7E-25 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 SMART SM00387 27 173 6.8E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 SUPERFAMILY SSF56719 389 622 1.73E-78 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 SMART SM00433 34 625 2.0E-208 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 SUPERFAMILY SSF54211 217 382 3.03E-44 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 312 327 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 449 470 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 239 262 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 295 311 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 363 388 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 470 482 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 538 560 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 339 362 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 504 520 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 9.1E-123 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 31 46 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 66 79 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 498 515 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 267 280 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 518 530 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 109 123 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 480 496 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 563 579 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 PRINTS PR00418 DNA topoisomerase II family signature 415 429 4.5E-58 T 13-10-2018 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Gene3D G3DSA:3.30.230.10 216 390 1.0E-53 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 171 2.3E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Gene3D G3DSA:3.40.50.670 391 624 9.8E-91 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Pfam PF00204 DNA gyrase B 218 385 6.3E-40 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Gene3D G3DSA:3.30.565.10 2 215 4.7E-75 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 Pfam PF01751 Toprim domain 414 523 1.2E-12 T 13-10-2018 IPR006171 TOPRIM domain MADE_1003570 ab38040dabc882961c9fb714a88c889b 631 SUPERFAMILY SSF55874 4 215 5.16E-66 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1008085 5248151db9ad9189edc7b00031189405 144 ProSitePatterns PS00938 Initiation factor 3 signature. 31 44 - T 13-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 MADE_1008085 5248151db9ad9189edc7b00031189405 144 SUPERFAMILY SSF54364 1 51 7.32E-19 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MADE_1008085 5248151db9ad9189edc7b00031189405 144 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 144 6.0E-63 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MADE_1008085 5248151db9ad9189edc7b00031189405 144 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 56 142 1.8E-37 T 13-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 MADE_1008085 5248151db9ad9189edc7b00031189405 144 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 144 22.64 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MADE_1008085 5248151db9ad9189edc7b00031189405 144 Gene3D G3DSA:3.30.110.10 49 144 6.0E-40 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MADE_1008085 5248151db9ad9189edc7b00031189405 144 Gene3D G3DSA:3.10.20.80 1 48 6.4E-20 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MADE_1008085 5248151db9ad9189edc7b00031189405 144 SUPERFAMILY SSF55200 56 144 9.55E-35 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 MADE_1008085 5248151db9ad9189edc7b00031189405 144 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 49 1.3E-19 T 13-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 MADE_000001020960 d2b1558cd4a8116f238c4c17b954a1b2 171 SUPERFAMILY SSF53254 12 165 1.1E-17 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_000001020960 d2b1558cd4a8116f238c4c17b954a1b2 171 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 12 163 2.7E-27 T 13-10-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 MADE_000001020960 d2b1558cd4a8116f238c4c17b954a1b2 171 SMART SM00855 11 132 5.8E-8 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MADE_000001020960 d2b1558cd4a8116f238c4c17b954a1b2 171 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 12 77 2.0E-8 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MADE_000001020960 d2b1558cd4a8116f238c4c17b954a1b2 171 Gene3D G3DSA:3.40.50.1240 11 170 1.3E-31 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 SUPERFAMILY SSF56542 136 501 3.53E-66 T 13-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 Gene3D G3DSA:3.90.770.10 186 498 2.0E-110 T 13-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 Gene3D G3DSA:3.30.70.420 240 354 2.0E-110 T 13-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 295 313 3.9E-38 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 437 458 3.9E-38 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 175 196 3.9E-38 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 206 226 3.9E-38 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 335 360 3.9E-38 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 144 512 3.8E-120 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1018245 2e262aae95f7d093aa64d709822391e2 514 SUPERFAMILY SSF55035 241 354 1.24E-38 T 13-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1008195 00352db3796d8416137d1a6c2a4301fc 419 Gene3D G3DSA:3.40.50.2000 135 414 6.5E-50 T 13-10-2018 MADE_1008195 00352db3796d8416137d1a6c2a4301fc 419 Pfam PF00534 Glycosyl transferases group 1 230 400 3.7E-36 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1008195 00352db3796d8416137d1a6c2a4301fc 419 SUPERFAMILY SSF53756 29 418 3.27E-56 T 13-10-2018 MADE_1008195 00352db3796d8416137d1a6c2a4301fc 419 Gene3D G3DSA:3.40.50.2000 228 406 6.5E-50 T 13-10-2018 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 Hamap MF_00186 Glycerol kinase [glpK]. 2 494 53.314 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 Gene3D G3DSA:3.30.420.40 1 252 1.3E-103 T 13-10-2018 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 490 7.5E-218 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 SUPERFAMILY SSF53067 4 254 6.65E-92 T 13-10-2018 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 448 6.5E-57 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 SUPERFAMILY SSF53067 254 491 4.36E-79 T 13-10-2018 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 PIRSF PIRSF000538 2 493 1.4E-168 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 Gene3D G3DSA:3.30.420.40 253 492 3.4E-86 T 13-10-2018 MADE_1001185 ca40bbc89a317bb795d6ef308b45492a 494 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 251 8.0E-76 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 MADE_1014275 c71abb9f0983216e25c147858696f657 154 SMART SM00988 1 65 1.6E-15 T 13-10-2018 IPR004029 UreE urease accessory, N-terminal MADE_1014275 c71abb9f0983216e25c147858696f657 154 Pfam PF02814 UreE urease accessory protein, N-terminal domain 12 65 2.5E-10 T 13-10-2018 IPR004029 UreE urease accessory, N-terminal MADE_1014275 c71abb9f0983216e25c147858696f657 154 Pfam PF05194 UreE urease accessory protein, C-terminal domain 72 152 6.7E-26 T 13-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 MADE_1014275 c71abb9f0983216e25c147858696f657 154 Gene3D G3DSA:2.60.260.20 1 69 1.4E-16 T 13-10-2018 MADE_1014275 c71abb9f0983216e25c147858696f657 154 SUPERFAMILY SSF69287 1 67 4.58E-12 T 13-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily MADE_1014275 c71abb9f0983216e25c147858696f657 154 Hamap MF_00822 Urease accessory protein UreE [ureE]. 6 139 21.49 T 13-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MADE_1014275 c71abb9f0983216e25c147858696f657 154 SUPERFAMILY SSF69737 72 138 6.93E-19 T 13-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 MADE_1014275 c71abb9f0983216e25c147858696f657 154 Gene3D G3DSA:3.30.70.790 72 142 5.5E-27 T 13-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 MADE_1014275 c71abb9f0983216e25c147858696f657 154 PIRSF PIRSF036402 3 153 8.4E-35 T 13-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Pfam PF00512 His Kinase A (phospho-acceptor) domain 531 596 2.5E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Pfam PF08446 PAS fold 14 128 1.6E-6 T 13-10-2018 IPR013654 PAS fold-2 GO:0006355 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SMART SM00448 781 898 1.4E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SUPERFAMILY SSF55781 159 324 3.19E-47 T 13-10-2018 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Gene3D G3DSA:3.30.450.20 18 264 1.7E-120 T 13-10-2018 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Gene3D G3DSA:3.30.565.10 599 754 1.9E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SUPERFAMILY SSF55781 311 509 2.75E-30 T 13-10-2018 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Pfam PF00072 Response regulator receiver domain 783 898 1.2E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SUPERFAMILY SSF47384 516 597 4.51E-18 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SMART SM00387 643 754 7.2E-41 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 698 708 8.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 738 751 8.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 713 731 8.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 680 694 8.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SUPERFAMILY SSF52172 779 902 2.13E-28 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Pfam PF01590 GAF domain 161 316 3.3E-13 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SUPERFAMILY SSF55785 7 129 1.36E-16 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Gene3D G3DSA:3.30.450.270 333 501 1.7E-120 T 13-10-2018 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SUPERFAMILY SSF55874 586 756 2.23E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Gene3D G3DSA:3.40.50.2300 770 905 2.4E-28 T 13-10-2018 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Gene3D G3DSA:1.10.287.130 515 598 5.3E-20 T 13-10-2018 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 643 752 2.1E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 SMART SM00388 531 597 7.9E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Gene3D G3DSA:3.30.450.40 14 487 1.7E-120 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1018105 ccb74832818e60a32696f4cc4d06c171 908 Pfam PF00360 Phytochrome region 342 501 2.2E-22 T 13-10-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 MADE_1008295 cd24ccf36bec1515d271e0b93aae0fae 156 Gene3D G3DSA:3.90.960.10 1 155 5.6E-51 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MADE_1008295 cd24ccf36bec1515d271e0b93aae0fae 156 Pfam PF04073 Aminoacyl-tRNA editing domain 32 144 1.2E-20 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 MADE_1008295 cd24ccf36bec1515d271e0b93aae0fae 156 SUPERFAMILY SSF55826 2 153 1.57E-39 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MADE_1008295 cd24ccf36bec1515d271e0b93aae0fae 156 PIRSF PIRSF006181 1 155 1.1E-49 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MADE_1008295 cd24ccf36bec1515d271e0b93aae0fae 156 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 153 4.6E-50 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC MADE_1013740 8cfabe2079d48c0571122da3e0c58bd8 758 SUPERFAMILY SSF56935 27 757 8.93E-114 T 13-10-2018 MADE_1013740 8cfabe2079d48c0571122da3e0c58bd8 758 Gene3D G3DSA:2.40.170.20 42 758 3.8E-135 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1013740 8cfabe2079d48c0571122da3e0c58bd8 758 Pfam PF00593 TonB dependent receptor 272 756 3.3E-39 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1013740 8cfabe2079d48c0571122da3e0c58bd8 758 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 160 1.7E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1002440 3fddafa6aef3763e17465b60805d82dc 358 SUPERFAMILY SSF55073 99 283 1.24E-55 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1002440 3fddafa6aef3763e17465b60805d82dc 358 Gene3D G3DSA:3.30.70.1230 93 299 2.4E-60 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1002440 3fddafa6aef3763e17465b60805d82dc 358 SUPERFAMILY SSF48452 172 342 1.32E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1002440 3fddafa6aef3763e17465b60805d82dc 358 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 98 280 7.9E-35 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MADE_1002440 3fddafa6aef3763e17465b60805d82dc 358 SMART SM00044 61 262 3.2E-22 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 Pfam PF03099 Biotin/lipoate A/B protein ligase family 91 217 1.3E-19 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 Gene3D G3DSA:1.10.10.10 4 64 4.3E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 Gene3D G3DSA:2.30.30.100 280 328 3.4E-16 T 13-10-2018 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 9 326 30.139 T 13-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 SUPERFAMILY SSF46785 8 62 2.14E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 SUPERFAMILY SSF55681 84 278 6.75E-56 T 13-10-2018 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 Pfam PF02237 Biotin protein ligase C terminal domain 284 326 3.0E-6 T 13-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 87 326 3.2E-57 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 Pfam PF08279 HTH domain 10 61 4.9E-10 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 SUPERFAMILY SSF50037 280 326 1.97E-9 T 13-10-2018 IPR008988 Transcriptional repressor, C-terminal MADE_000001023210 3000cfd6569eead3e8d19e7e970e6fcc 328 Gene3D G3DSA:3.30.930.10 70 279 3.6E-58 T 13-10-2018 MADE_1008820 435ce2144dca772cdb59fdef3123683d 291 Gene3D G3DSA:3.20.20.140 7 291 6.4E-51 T 13-10-2018 MADE_1008820 435ce2144dca772cdb59fdef3123683d 291 SUPERFAMILY SSF51556 8 290 1.02E-33 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1008820 435ce2144dca772cdb59fdef3123683d 291 Pfam PF04909 Amidohydrolase 162 290 2.8E-14 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 PIRSF PIRSF000197 2 1261 0.0 T 13-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 Gene3D G3DSA:3.40.309.10 784 976 2.1E-142 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 SUPERFAMILY SSF81935 11 182 1.96E-60 T 13-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 Pfam PF01619 Proline dehydrogenase 192 482 3.8E-94 T 13-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 Gene3D G3DSA:3.20.20.220 139 521 1.1E-134 T 13-10-2018 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 SUPERFAMILY SSF53720 560 1005 2.09E-124 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 67 180 6.3E-45 T 13-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 809 820 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 Gene3D G3DSA:3.40.605.10 562 1007 2.1E-142 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 Pfam PF00171 Aldehyde dehydrogenase family 563 1003 6.7E-116 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 SUPERFAMILY SSF51730 183 526 5.89E-114 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 519 1005 2.5E-195 T 13-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 Gene3D G3DSA:3.40.605.10 1018 1233 1.8E-9 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1003410 d09d686de79c2a71b0e19aa3ea862719 1265 SUPERFAMILY SSF53720 1034 1217 1.03E-11 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1003060 587d3dea2b941f687ce52a5057ee3eb2 97 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 83 4.1E-33 T 13-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 MADE_1003060 587d3dea2b941f687ce52a5057ee3eb2 97 SMART SM00530 12 68 0.0015 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1003060 587d3dea2b941f687ce52a5057ee3eb2 97 Pfam PF01381 Helix-turn-helix 18 66 1.7E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1003060 587d3dea2b941f687ce52a5057ee3eb2 97 Gene3D G3DSA:1.10.260.40 1 95 3.1E-31 T 13-10-2018 MADE_1003060 587d3dea2b941f687ce52a5057ee3eb2 97 SUPERFAMILY SSF47413 8 90 3.66E-26 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 Hamap MF_00303 Trigger factor [tig]. 1 420 22.276 T 13-10-2018 IPR005215 Trigger factor GO:0015031 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 SUPERFAMILY SSF102735 1 131 1.31E-41 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 415 4.4E-39 T 13-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 Gene3D G3DSA:1.10.3120.10 116 419 1.5E-102 T 13-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 6.2E-43 T 13-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 Gene3D G3DSA:3.30.70.1050 1 115 2.0E-41 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 155 229 2.6E-14 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 SUPERFAMILY SSF109998 248 431 5.2E-48 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 Gene3D G3DSA:3.10.50.40 150 246 1.5E-102 T 13-10-2018 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 SUPERFAMILY SSF54534 88 241 3.14E-39 T 13-10-2018 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 PIRSF PIRSF003095 1 434 1.3E-130 T 13-10-2018 IPR005215 Trigger factor GO:0015031 MADE_1012760 0e0a7733658090c9d50ae31b1c350bf6 434 TIGRFAM TIGR00115 tig: trigger factor 11 414 1.1E-146 T 13-10-2018 IPR005215 Trigger factor GO:0015031 MADE_1015920 0041fe69ecca4b1960aa50dde5bb7d8a 264 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 160 261 3.5E-32 T 13-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 MADE_1015920 0041fe69ecca4b1960aa50dde5bb7d8a 264 SUPERFAMILY SSF63848 159 263 1.7E-31 T 13-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 MADE_1015920 0041fe69ecca4b1960aa50dde5bb7d8a 264 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 6 263 2.1E-56 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MADE_1015920 0041fe69ecca4b1960aa50dde5bb7d8a 264 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 5 264 25.279 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 MADE_1015920 0041fe69ecca4b1960aa50dde5bb7d8a 264 Gene3D G3DSA:3.30.750.120 1 116 2.0E-18 T 13-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily MADE_1015920 0041fe69ecca4b1960aa50dde5bb7d8a 264 Gene3D G3DSA:2.160.20.70 156 264 1.1E-32 T 13-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 MADE_1015920 0041fe69ecca4b1960aa50dde5bb7d8a 264 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 3 101 1.4E-11 T 13-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 246 265 1.3E-20 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 120 139 1.3E-20 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 337 355 1.3E-20 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 392 407 1.3E-20 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 29 54 1.3E-20 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 361 379 1.3E-20 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 217 233 1.3E-20 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 SUPERFAMILY SSF56235 6 520 1.06E-138 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 Gene3D G3DSA:3.60.20.40 338 522 9.2E-57 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 Gene3D G3DSA:1.10.246.130 233 337 1.6E-13 T 13-10-2018 MADE_1008030 4751ccedb50ebf5227c97446c6e1231b 525 Pfam PF01019 Gamma-glutamyltranspeptidase 22 518 1.6E-118 T 13-10-2018 MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 SUPERFAMILY SSF53067 146 236 9.58E-20 T 13-10-2018 MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 Pfam PF12693 GspL periplasmic domain 246 397 1.2E-28 T 13-10-2018 IPR025691 GspL periplasmic domain MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 Gene3D G3DSA:3.30.420.380 2 235 2.8E-80 T 13-10-2018 MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 Gene3D G3DSA:3.30.1360.100 313 399 5.5E-24 T 13-10-2018 MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 PIRSF PIRSF015761 19 399 4.8E-26 T 13-10-2018 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 TIGRFAM TIGR01709 typeII_sec_gspL: type II secretion system protein L 4 397 2.9E-76 T 13-10-2018 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 SUPERFAMILY SSF53067 1 142 6.86E-38 T 13-10-2018 MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 Pfam PF05134 Type II secretion system (T2SS), protein L 4 237 6.8E-56 T 13-10-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain MADE_1019865 5624522053f73cd9782e4f2f48f54249 399 Gene3D G3DSA:3.30.420.370 141 213 2.8E-80 T 13-10-2018 MADE_1018110 ad273232f21a8a785021c0b36ac8f8e8 185 PIRSF PIRSF006707 1 176 1.1E-47 T 13-10-2018 IPR026282 DNA-binding protein, MJ1563 type MADE_1018110 ad273232f21a8a785021c0b36ac8f8e8 185 Gene3D G3DSA:1.10.10.10 6 85 3.5E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1018110 ad273232f21a8a785021c0b36ac8f8e8 185 SUPERFAMILY SSF46785 6 145 7.65E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1018110 ad273232f21a8a785021c0b36ac8f8e8 185 Pfam PF12802 MarR family 22 72 7.5E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1019700 6a560ceb0c52dd48db5a1e9387ce3707 63 Pfam PF14255 Cysteine-rich CPXCG 10 57 4.5E-13 T 13-10-2018 IPR025990 Cysteine-rich CPXCG protein MADE_1019700 6a560ceb0c52dd48db5a1e9387ce3707 63 PIRSF PIRSF037225 3 63 1.9E-17 T 13-10-2018 IPR017143 Uncharacterised conserved protein UCP037225 MADE_1002530 4f2f8318aa133f18645895f3235ba39b 225 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MADE_1002530 4f2f8318aa133f18645895f3235ba39b 225 SUPERFAMILY SSF51366 4 218 3.25E-73 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MADE_1002530 4f2f8318aa133f18645895f3235ba39b 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MADE_1002530 4f2f8318aa133f18645895f3235ba39b 225 PIRSF PIRSF001461 1 225 8.3E-102 T 13-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MADE_1002530 4f2f8318aa133f18645895f3235ba39b 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 5.0E-95 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MADE_1002530 4f2f8318aa133f18645895f3235ba39b 225 Gene3D G3DSA:3.20.20.70 5 221 2.1E-82 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1002530 4f2f8318aa133f18645895f3235ba39b 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 2.2E-88 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 MADE_1010340 8247368d8c78a8720884c02564172b29 129 SUPERFAMILY SSF46955 4 126 2.09E-29 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1010340 8247368d8c78a8720884c02564172b29 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 9.9E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010340 8247368d8c78a8720884c02564172b29 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 9.9E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010340 8247368d8c78a8720884c02564172b29 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 9.9E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010340 8247368d8c78a8720884c02564172b29 129 Gene3D G3DSA:1.10.1660.10 2 125 5.4E-34 T 13-10-2018 MADE_1010340 8247368d8c78a8720884c02564172b29 129 Pfam PF13411 MerR HTH family regulatory protein 4 70 3.3E-19 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010340 8247368d8c78a8720884c02564172b29 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010340 8247368d8c78a8720884c02564172b29 129 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 4 126 1.1E-50 T 13-10-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 MADE_1010340 8247368d8c78a8720884c02564172b29 129 SMART SM00422 4 72 1.5E-24 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 SUPERFAMILY SSF52540 202 450 7.41E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 SMART SM00490 502 586 6.9E-21 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 661 2.5E-229 T 13-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 Gene3D G3DSA:3.40.50.300 206 447 1.5E-82 T 13-10-2018 MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 Gene3D G3DSA:2.40.50.140 45 138 3.4E-11 T 13-10-2018 MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 SMART SM00487 262 456 1.6E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 Pfam PF00271 Helicase conserved C-terminal domain 477 585 1.4E-16 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 Pfam PF17191 RecG wedge domain 9 169 7.1E-22 T 13-10-2018 IPR033454 RecG, wedge domain MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 SUPERFAMILY SSF50249 6 171 9.71E-41 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 SUPERFAMILY SSF52540 449 651 7.35E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 Pfam PF00270 DEAD/DEAH box helicase 270 428 4.5E-18 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1000785 0b527068a84a170acb7d61c3f279434e 690 Gene3D G3DSA:3.40.50.300 454 627 2.0E-51 T 13-10-2018 MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 3.1E-66 T 13-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 2.6E-26 T 13-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 SUPERFAMILY SSF54747 3 73 4.97E-30 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 13-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 8.0E-15 T 13-10-2018 MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 7.4E-30 T 13-10-2018 IPR020784 Ribosomal protein L11, N-terminal MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 Gene3D G3DSA:1.10.10.2720 73 142 8.0E-30 T 13-10-2018 MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 SUPERFAMILY SSF46906 68 141 3.4E-27 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 Gene3D G3DSA:3.30.1550.10 2 72 2.9E-35 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.983 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MADE_000001023320 4762cafee8ad7c874eaa1b6ce0635d5a 142 SMART SM00649 9 141 3.0E-87 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 MADE_1013110 3b51b606aa06dea078d10569804917f7 287 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 54 285 6.5E-76 T 13-10-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted MADE_1013110 3b51b606aa06dea078d10569804917f7 287 Gene3D G3DSA:3.40.630.30 63 272 5.6E-50 T 13-10-2018 MADE_1013110 3b51b606aa06dea078d10569804917f7 287 Pfam PF13444 Acetyltransferase (GNAT) domain 77 176 2.6E-17 T 13-10-2018 MADE_1013110 3b51b606aa06dea078d10569804917f7 287 SUPERFAMILY SSF55729 57 259 5.09E-29 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_000001020680 d58efdd866bcb9dce8bd0484c29cf241 249 Gene3D G3DSA:3.10.560.10 147 220 5.8E-17 T 13-10-2018 MADE_000001020680 d58efdd866bcb9dce8bd0484c29cf241 249 Pfam PF06251 Capsule biosynthesis GfcC 25 245 4.0E-42 T 13-10-2018 IPR010425 Domain of unknown function DUF1017 MADE_1020000 4f5bd1e7bf3ce0549092aee2c9e4a100 327 Pfam PF12118 SprA-related family 113 247 1.7E-44 T 13-10-2018 IPR021973 SprA-related family MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 SUPERFAMILY SSF47323 669 866 8.22E-38 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Gene3D G3DSA:3.10.330.110 573 635 0.0 T 13-10-2018 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 SUPERFAMILY SSF50677 227 421 3.14E-52 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 6 866 0.0 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 223 410 7.3E-77 T 13-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 172 1.9E-27 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 423 578 5.8E-9 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 625 661 3.3E-6 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Gene3D G3DSA:1.10.730.10 9 798 0.0 T 13-10-2018 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 5 866 23.778 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Gene3D G3DSA:3.90.740.10 228 420 0.0 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 PRINTS PR00985 Leucyl-tRNA synthetase signature 128 145 1.3E-51 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 PRINTS PR00985 Leucyl-tRNA synthetase signature 563 573 1.3E-51 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 PRINTS PR00985 Leucyl-tRNA synthetase signature 216 235 1.3E-51 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 PRINTS PR00985 Leucyl-tRNA synthetase signature 491 509 1.3E-51 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 PRINTS PR00985 Leucyl-tRNA synthetase signature 154 170 1.3E-51 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 PRINTS PR00985 Leucyl-tRNA synthetase signature 530 552 1.3E-51 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 1.3E-51 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Gene3D G3DSA:3.40.50.620 34 572 0.0 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Gene3D G3DSA:3.10.20.590 806 866 9.6E-24 T 13-10-2018 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 SUPERFAMILY SSF52374 5 675 7.85E-146 T 13-10-2018 MADE_000001021845 6adf4ab37f97eeaef0fb61a1867fcbb8 867 Pfam PF08264 Anticodon-binding domain of tRNA 707 830 7.3E-19 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Gene3D G3DSA:3.30.450.20 165 229 1.1E-8 T 13-10-2018 MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Pfam PF00563 EAL domain 602 836 7.0E-62 T 13-10-2018 IPR001633 EAL domain MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SUPERFAMILY SSF55073 425 578 1.18E-21 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Gene3D G3DSA:3.30.70.270 413 586 1.9E-26 T 13-10-2018 MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SUPERFAMILY SSF55785 173 282 5.58E-11 T 13-10-2018 IPR035965 PAS domain superfamily MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SMART SM00267 408 584 1.3E-8 T 13-10-2018 IPR000160 GGDEF domain MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 291 413 1.5E-23 T 13-10-2018 IPR000014 PAS domain MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SMART SM00091 292 358 6.7E-10 T 13-10-2018 IPR000014 PAS domain MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Pfam PF00990 Diguanylate cyclase, GGDEF domain 419 577 5.6E-22 T 13-10-2018 IPR000160 GGDEF domain MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Pfam PF00989 PAS fold 294 405 9.0E-15 T 13-10-2018 IPR013767 PAS fold GO:0006355 MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Gene3D G3DSA:2.10.70.100 235 281 1.4E-8 T 13-10-2018 MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SUPERFAMILY SSF55785 303 414 1.05E-24 T 13-10-2018 IPR035965 PAS domain superfamily MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SMART SM00086 368 408 39.0 T 13-10-2018 IPR001610 PAC motif MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SMART SM00086 238 280 0.012 T 13-10-2018 IPR001610 PAC motif MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Pfam PF08447 PAS fold 189 272 7.0E-6 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Gene3D G3DSA:3.20.20.450 597 850 1.0E-82 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 417 577 3.8E-23 T 13-10-2018 IPR000160 GGDEF domain MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SUPERFAMILY SSF141868 601 847 1.96E-79 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 SMART SM00052 595 841 3.1E-89 T 13-10-2018 IPR001633 EAL domain MADE_000001023170 2b8c06247f021d056929a4e60d07b416 852 Gene3D G3DSA:3.30.450.20 288 409 3.0E-32 T 13-10-2018 MADE_1001875 1759861478468a4442c3af04f1793c5d 479 Gene3D G3DSA:1.10.287.130 207 323 4.4E-8 T 13-10-2018 MADE_1001875 1759861478468a4442c3af04f1793c5d 479 SUPERFAMILY SSF47384 241 320 2.55E-7 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1001875 1759861478468a4442c3af04f1793c5d 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 472 4.6E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1001875 1759861478468a4442c3af04f1793c5d 479 Gene3D G3DSA:3.30.565.10 327 477 1.3E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1001875 1759861478468a4442c3af04f1793c5d 479 SMART SM00387 363 476 8.9E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1001875 1759861478468a4442c3af04f1793c5d 479 SUPERFAMILY SSF55874 331 473 2.36E-18 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 13-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 4.1E-58 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 3.7E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 3.7E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 3.7E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 3.7E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 3.7E-25 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.574 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 175 2.2E-52 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 SUPERFAMILY SSF47928 3 105 5.75E-24 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023710 35e1a28b79f20fd381ab6d0078e6604c 177 Gene3D G3DSA:1.10.520.20 2 106 5.4E-37 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.0E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.0E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.0E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 SUPERFAMILY SSF51735 5 243 5.37E-69 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 240 3.4E-49 T 13-10-2018 MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.2E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.2E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.2E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 5.2E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 5.2E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.2E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008070 312bf6d21dfb15a8715340b86528aace 249 Gene3D G3DSA:3.40.50.720 1 245 7.7E-66 T 13-10-2018 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 Pfam PF02436 Conserved carboxylase domain 292 500 1.4E-59 T 13-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 560 577 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 7 599 4.0E-260 T 13-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 Gene3D G3DSA:2.40.50.100 527 603 4.3E-24 T 13-10-2018 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 SUPERFAMILY SSF51569 1 300 4.21E-85 T 13-10-2018 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 Gene3D G3DSA:3.20.20.70 1 463 9.1E-165 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 SUPERFAMILY SSF51230 529 603 6.02E-21 T 13-10-2018 IPR011053 Single hybrid motif MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 SUPERFAMILY SSF89000 297 461 4.32E-50 T 13-10-2018 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 Pfam PF00682 HMGL-like 6 270 1.5E-49 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MADE_1006120 196630e6f5099333752d2fb54d39afd5 604 Pfam PF00364 Biotin-requiring enzyme 538 602 3.0E-18 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1004015 9adc72db96f199f036afa8fe2c112257 573 Gene3D G3DSA:3.10.310.30 325 454 2.0E-29 T 13-10-2018 MADE_1004015 9adc72db96f199f036afa8fe2c112257 573 Pfam PF02272 DHHA1 domain 319 448 6.1E-23 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MADE_1004015 9adc72db96f199f036afa8fe2c112257 573 Pfam PF01368 DHH family 71 203 2.8E-7 T 13-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 MADE_1004015 9adc72db96f199f036afa8fe2c112257 573 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 20 569 1.4E-155 T 13-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 MADE_1004015 9adc72db96f199f036afa8fe2c112257 573 Gene3D G3DSA:3.90.1640.30 45 323 4.1E-88 T 13-10-2018 MADE_1004015 9adc72db96f199f036afa8fe2c112257 573 SUPERFAMILY SSF64182 46 456 1.44E-114 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 360 1.6E-156 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 Pfam PF01926 50S ribosome-binding GTPase 200 318 6.4E-21 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 SUPERFAMILY SSF54980 365 421 6.26E-16 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 SUPERFAMILY SSF52540 197 373 1.63E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 PIRSF PIRSF006809 3 421 7.9E-151 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 Hamap MF_00900 GTPase HflX [hflX]. 27 390 47.217 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 Gene3D G3DSA:3.40.50.300 197 369 3.1E-38 T 13-10-2018 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 3.5E-10 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 3.5E-10 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 3.5E-10 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 1.9E-31 T 13-10-2018 IPR025121 GTPase HflX, N-terminal MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 4.6E-28 T 13-10-2018 IPR032305 GTP-binding protein, middle domain MADE_000001023545 a9b95ea3e680e481bb4c7e467d6b0ddf 429 Gene3D G3DSA:3.40.50.11060 17 138 4.7E-39 T 13-10-2018 MADE_1019855 2ac3e4fb8a9004044f5c2b5aeadfc143 208 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 23 1.1E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019855 2ac3e4fb8a9004044f5c2b5aeadfc143 208 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 2 23 1.4E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019855 2ac3e4fb8a9004044f5c2b5aeadfc143 208 Gene3D G3DSA:3.10.610.10 35 145 6.7E-37 T 13-10-2018 MADE_1019855 2ac3e4fb8a9004044f5c2b5aeadfc143 208 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 3 23 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019855 2ac3e4fb8a9004044f5c2b5aeadfc143 208 Pfam PF11612 Type II secretion system (T2SS), protein J 55 200 1.0E-37 T 13-10-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 MADE_1019855 2ac3e4fb8a9004044f5c2b5aeadfc143 208 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 3 202 1.8E-55 T 13-10-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 MADE_1019855 2ac3e4fb8a9004044f5c2b5aeadfc143 208 SUPERFAMILY SSF54523 36 204 1.81E-43 T 13-10-2018 MADE_1009835 b82150b69682dcb9c33fe925bb0876c0 235 SUPERFAMILY SSF100950 4 226 7.33E-86 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1009835 b82150b69682dcb9c33fe925bb0876c0 235 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 20 35 - T 13-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 MADE_1009835 b82150b69682dcb9c33fe925bb0876c0 235 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 5 218 1.8E-71 T 13-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 MADE_1009835 b82150b69682dcb9c33fe925bb0876c0 235 SMART SM00882 8 219 1.9E-87 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MADE_1009835 b82150b69682dcb9c33fe925bb0876c0 235 Gene3D G3DSA:3.40.1080.10 2 228 1.4E-95 T 13-10-2018 MADE_1009835 b82150b69682dcb9c33fe925bb0876c0 235 Pfam PF01144 Coenzyme A transferase 10 218 2.0E-73 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MADE_1002980 e7cddf024579270ef7359b0c4e357a6e 331 Pfam PF13580 SIS domain 67 191 1.3E-7 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MADE_1002980 e7cddf024579270ef7359b0c4e357a6e 331 Gene3D G3DSA:3.40.50.10490 32 250 6.4E-75 T 13-10-2018 MADE_1002980 e7cddf024579270ef7359b0c4e357a6e 331 SUPERFAMILY SSF53697 37 281 3.56E-69 T 13-10-2018 MADE_1002980 e7cddf024579270ef7359b0c4e357a6e 331 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 34 327 41.848 T 13-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 MADE_1002980 e7cddf024579270ef7359b0c4e357a6e 331 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 217 234 - T 13-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 MADE_1002980 e7cddf024579270ef7359b0c4e357a6e 331 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 38 327 1.7E-124 T 13-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 MADE_1002980 e7cddf024579270ef7359b0c4e357a6e 331 Gene3D G3DSA:1.10.8.1080 251 329 2.4E-28 T 13-10-2018 MADE_1015590 b69f7644187a6abccd523ba05219225c 347 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 38 207 8.7E-23 T 13-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal MADE_1015590 b69f7644187a6abccd523ba05219225c 347 Gene3D G3DSA:1.10.10.60 241 346 5.2E-20 T 13-10-2018 MADE_1015590 b69f7644187a6abccd523ba05219225c 347 SUPERFAMILY SSF46689 308 345 7.77E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1015590 b69f7644187a6abccd523ba05219225c 347 Pfam PF12833 Helix-turn-helix domain 268 343 3.8E-16 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1015590 b69f7644187a6abccd523ba05219225c 347 SMART SM00342 262 342 2.7E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 Gene3D G3DSA:1.10.1040.10 291 496 1.1E-56 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 226 469 1.6E-66 T 13-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 228 240 - T 13-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 PRINTS PR00084 Mannitol dehydrogenase signature 257 272 1.2E-21 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 PRINTS PR00084 Mannitol dehydrogenase signature 35 45 1.2E-21 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 PRINTS PR00084 Mannitol dehydrogenase signature 189 202 1.2E-21 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 PRINTS PR00084 Mannitol dehydrogenase signature 228 241 1.2E-21 T 13-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 SUPERFAMILY SSF48179 292 486 5.78E-49 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 34 198 3.2E-47 T 13-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 Gene3D G3DSA:3.40.50.720 8 290 1.0E-111 T 13-10-2018 MADE_1008855 6a9be6aed7d020c487fbaa65adc3609d 511 SUPERFAMILY SSF51735 10 290 3.66E-101 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 PRINTS PR00702 Acriflavin resistance protein family signature 375 396 2.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 PRINTS PR00702 Acriflavin resistance protein family signature 580 597 2.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 PRINTS PR00702 Acriflavin resistance protein family signature 348 371 2.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 PRINTS PR00702 Acriflavin resistance protein family signature 403 427 2.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 SUPERFAMILY SSF82714 187 274 3.14E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 SUPERFAMILY SSF82714 752 835 2.88E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:1.20.1640.10 543 1053 5.5E-280 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:3.30.70.1430 597 700 5.5E-280 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:3.30.70.1440 701 898 5.5E-280 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:3.30.2090.10 752 840 5.5E-280 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 SUPERFAMILY SSF82866 836 1060 2.35E-56 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 SUPERFAMILY SSF82693 43 129 6.54E-21 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 SUPERFAMILY SSF82693 142 341 8.89E-14 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1058 0.0 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:3.30.70.1430 42 848 5.5E-280 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:3.30.70.1320 136 342 5.5E-280 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:1.20.1640.10 16 542 5.5E-280 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Pfam PF00873 AcrB/AcrD/AcrF family 6 1056 1.6E-272 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 SUPERFAMILY SSF82693 595 694 1.12E-7 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 SUPERFAMILY SSF82866 308 534 3.92E-44 T 13-10-2018 MADE_1010300 01cc1c3f75ed93a0872ac2d6e7b142d5 1069 Gene3D G3DSA:3.30.2090.10 184 279 5.5E-280 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 SUPERFAMILY SSF50249 6 144 1.71E-33 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 Gene3D G3DSA:2.40.50.140 2 143 6.0E-30 T 13-10-2018 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 Gene3D G3DSA:3.30.930.10 147 522 4.4E-131 T 13-10-2018 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 SUPERFAMILY SSF55681 151 508 1.11E-114 T 13-10-2018 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 Pfam PF01336 OB-fold nucleic acid binding domain 63 135 1.4E-8 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 9 510 1.7E-196 T 13-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 Pfam PF00152 tRNA synthetases class II (D, K and N) 151 507 1.9E-82 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 PRINTS PR00982 Lysyl-tRNA synthetase signature 251 268 2.8E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 PRINTS PR00982 Lysyl-tRNA synthetase signature 233 246 2.8E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 PRINTS PR00982 Lysyl-tRNA synthetase signature 204 220 2.8E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 PRINTS PR00982 Lysyl-tRNA synthetase signature 188 198 2.8E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 PRINTS PR00982 Lysyl-tRNA synthetase signature 392 408 2.8E-38 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1006470 85e6020ed6b939ed89530fe0f115609b 522 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 14 510 43.145 T 13-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1006365 50eee06dff4c04df9101df0098112e34 343 Pfam PF11168 Protein of unknown function (DUF2955) 12 151 2.9E-36 T 13-10-2018 IPR022604 Protein of unknown function DUF2955 MADE_1006365 50eee06dff4c04df9101df0098112e34 343 Pfam PF13515 Fusaric acid resistance protein-like 191 323 1.3E-5 T 13-10-2018 MADE_1006365 50eee06dff4c04df9101df0098112e34 343 PIRSF PIRSF029594 5 342 6.0E-109 T 13-10-2018 IPR016926 Uncharacterised conserved protein UCP029594 MADE_000001022795 9d394df50934e9a182cbd4b8c9534ef9 206 Gene3D G3DSA:3.40.50.720 1 205 5.8E-54 T 13-10-2018 MADE_000001022795 9d394df50934e9a182cbd4b8c9534ef9 206 Pfam PF13460 NAD(P)H-binding 8 126 1.0E-9 T 13-10-2018 IPR016040 NAD(P)-binding domain MADE_000001022795 9d394df50934e9a182cbd4b8c9534ef9 206 SUPERFAMILY SSF51735 1 202 5.81E-40 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 SUPERFAMILY SSF75217 70 245 1.7E-49 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 Pfam PF00588 SpoU rRNA Methylase family 98 238 1.1E-40 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 SUPERFAMILY SSF55315 2 78 6.47E-19 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 245 43.621 T 13-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 80 9.3E-17 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 244 1.5E-82 T 13-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 SMART SM00967 6 82 7.8E-16 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 Gene3D G3DSA:3.30.1330.30 1 78 2.1E-26 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like MADE_1018015 cd5c987d1ec7490d149a2b2b91128c42 246 Gene3D G3DSA:3.40.1280.10 80 245 2.5E-63 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 SUPERFAMILY SSF52172 9 134 1.12E-39 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 SMART SM00471 155 293 4.6E-7 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 SUPERFAMILY SSF109604 140 324 4.71E-39 T 13-10-2018 MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 SMART SM00448 13 125 1.5E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 Pfam PF00072 Response regulator receiver domain 16 125 4.5E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 Gene3D G3DSA:1.10.3210.10 139 337 8.2E-73 T 13-10-2018 MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 Gene3D G3DSA:3.40.50.2300 9 138 1.0E-39 T 13-10-2018 MADE_1008905 aac41ef8b63cf5236f1ce1eede95d572 337 Pfam PF01966 HD domain 162 283 1.5E-16 T 13-10-2018 IPR006674 HD domain MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 Gene3D G3DSA:1.10.1040.10 209 492 2.2E-114 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 Gene3D G3DSA:3.40.50.720 1 208 1.0E-82 T 13-10-2018 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 22 488 36.433 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 367 1.0E-116 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 5.8E-57 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 342 2.8E-27 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 355 485 4.5E-20 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 SUPERFAMILY SSF48179 210 370 3.91E-40 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 SUPERFAMILY SSF48179 348 487 1.09E-41 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1020145 be367a6fd210d64fa8ce3d35227cc4ef 492 SUPERFAMILY SSF51735 28 209 1.85E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1007515 a7f55c11cccc061e144c6ca51a2a19f5 382 Gene3D G3DSA:3.40.50.2000 141 366 3.0E-25 T 13-10-2018 MADE_1007515 a7f55c11cccc061e144c6ca51a2a19f5 382 Gene3D G3DSA:3.40.50.2000 187 362 3.0E-25 T 13-10-2018 MADE_1007515 a7f55c11cccc061e144c6ca51a2a19f5 382 SUPERFAMILY SSF53756 60 371 4.71E-32 T 13-10-2018 MADE_1007515 a7f55c11cccc061e144c6ca51a2a19f5 382 Pfam PF13692 Glycosyl transferases group 1 206 342 8.7E-29 T 13-10-2018 MADE_1008975 18e86e24a6c1e499a86991799f17a5aa 561 Pfam PF00072 Response regulator receiver domain 16 130 3.6E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008975 18e86e24a6c1e499a86991799f17a5aa 561 SMART SM00448 14 130 2.0E-7 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008975 18e86e24a6c1e499a86991799f17a5aa 561 Gene3D G3DSA:3.40.50.2300 9 138 2.3E-15 T 13-10-2018 MADE_1008975 18e86e24a6c1e499a86991799f17a5aa 561 Gene3D G3DSA:1.25.40.10 139 361 1.5E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008975 18e86e24a6c1e499a86991799f17a5aa 561 SUPERFAMILY SSF48452 175 286 5.84E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008975 18e86e24a6c1e499a86991799f17a5aa 561 SUPERFAMILY SSF52172 13 148 5.86E-17 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 Pfam PF00072 Response regulator receiver domain 5 114 2.5E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 Gene3D G3DSA:1.10.10.60 390 448 1.0E-11 T 13-10-2018 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 Gene3D G3DSA:1.10.8.60 314 381 2.0E-22 T 13-10-2018 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 Gene3D G3DSA:3.40.50.2300 1 133 6.9E-22 T 13-10-2018 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 SMART SM00382 163 306 6.9E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 SUPERFAMILY SSF52172 4 188 5.55E-30 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 TIGRFAM TIGR02915 PEP_resp_reg: PEP-CTERM-box response regulator transcription factor 5 446 3.9E-211 T 13-10-2018 IPR014264 Signal transduction response regulator, PEP-CTERM system, putative MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 Pfam PF00158 Sigma-54 interaction domain 143 309 4.0E-72 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 SUPERFAMILY SSF46689 356 446 3.58E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 Pfam PF02954 Bacterial regulatory protein, Fis family 405 443 9.8E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 410 427 8.8E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 427 447 8.8E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 SMART SM00448 3 117 3.9E-12 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 Gene3D G3DSA:3.40.50.300 134 313 2.4E-67 T 13-10-2018 MADE_1015275 98eb6b449c725316dafb707bb60c3bf4 453 SUPERFAMILY SSF52540 143 384 2.6E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 17 236 1.9E-81 T 13-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 SUPERFAMILY SSF88659 91 155 2.79E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 Pfam PF04545 Sigma-70, region 4 184 232 1.1E-17 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 44 57 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 PIRSF PIRSF000770 4 243 7.9E-32 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 SUPERFAMILY SSF88946 10 89 1.1E-23 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 Pfam PF04539 Sigma-70 region 3 99 141 3.9E-7 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 Pfam PF04542 Sigma-70 region 2 17 89 6.6E-17 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 5 238 63.508 T 13-10-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 Gene3D G3DSA:1.20.140.160 88 237 1.9E-41 T 13-10-2018 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 235 2.6E-32 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 SUPERFAMILY SSF88659 163 238 1.53E-20 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 Gene3D G3DSA:1.10.1740.10 2 86 2.1E-29 T 13-10-2018 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 PRINTS PR00046 Major sigma-70 factor signature 44 57 6.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 PRINTS PR00046 Major sigma-70 factor signature 188 200 6.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 PRINTS PR00046 Major sigma-70 factor signature 220 231 6.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1005985 9a93b1d3eadd508f9022afd9c4e9239d 243 PRINTS PR00046 Major sigma-70 factor signature 205 220 6.7E-13 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1000700 8d5f4e7b30c06b0e5119b7e563379b6a 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 247 5.8E-106 T 13-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MADE_1000700 8d5f4e7b30c06b0e5119b7e563379b6a 256 SUPERFAMILY SSF110399 1 235 1.14E-78 T 13-10-2018 MADE_1000700 8d5f4e7b30c06b0e5119b7e563379b6a 256 Hamap MF_00443 Thiazole synthase [thiG]. 1 253 41.313 T 13-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 MADE_1000700 8d5f4e7b30c06b0e5119b7e563379b6a 256 Gene3D G3DSA:3.20.20.70 1 253 6.4E-106 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SUPERFAMILY SSF48452 245 370 9.87E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Pfam PF14559 Tetratricopeptide repeat 214 272 5.1E-9 T 13-10-2018 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Pfam PF14559 Tetratricopeptide repeat 870 934 5.2E-7 T 13-10-2018 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Gene3D G3DSA:1.25.40.10 595 924 8.0E-38 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Gene3D G3DSA:1.25.40.10 417 594 1.8E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Pfam PF13181 Tetratricopeptide repeat 723 751 0.0032 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SUPERFAMILY SSF48452 451 814 3.41E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Gene3D G3DSA:1.25.40.10 113 292 2.4E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Pfam PF13432 Tetratricopeptide repeat 325 380 0.0016 T 13-10-2018 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Pfam PF13432 Tetratricopeptide repeat 488 549 0.002 T 13-10-2018 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SUPERFAMILY SSF48452 36 118 1.77E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 31 918 1.0E-113 T 13-10-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 482 515 0.019 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 32 65 11.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 168 201 12.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 824 856 230.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 720 753 0.0079 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 618 651 200.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 891 924 35.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 516 549 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 857 890 180.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 202 235 0.013 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 312 345 320.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 550 583 35.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SMART SM00028 236 269 300.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Gene3D G3DSA:1.25.40.10 315 416 3.8E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SUPERFAMILY SSF48452 778 914 6.33E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 SUPERFAMILY SSF48452 136 272 4.74E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022265 aa324e3603430c721f9587f3a5abc531 937 Gene3D G3DSA:1.25.40.10 30 103 6.3E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1009155 130dc2c41481f81864baa5af6fe4c40d 240 SUPERFAMILY SSF52540 6 215 5.33E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009155 130dc2c41481f81864baa5af6fe4c40d 240 Pfam PF00005 ABC transporter 22 165 2.6E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1009155 130dc2c41481f81864baa5af6fe4c40d 240 Gene3D G3DSA:3.40.50.300 1 225 1.1E-55 T 13-10-2018 MADE_1009155 130dc2c41481f81864baa5af6fe4c40d 240 SMART SM00382 31 212 2.2E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1013260 31f65a6c64206a2ac0aeca7f56719f53 172 Hamap MF_00017 Recombination protein RecR [recR]. 1 172 88.501 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MADE_1013260 31f65a6c64206a2ac0aeca7f56719f53 172 Gene3D G3DSA:3.40.1360.10 50 172 1.4E-41 T 13-10-2018 MADE_1013260 31f65a6c64206a2ac0aeca7f56719f53 172 Pfam PF02132 RecR protein 13 50 1.1E-14 T 13-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger MADE_1013260 31f65a6c64206a2ac0aeca7f56719f53 172 SUPERFAMILY SSF111304 1 172 2.35E-62 T 13-10-2018 IPR023627 Recombination protein RecR MADE_1013260 31f65a6c64206a2ac0aeca7f56719f53 172 Pfam PF13662 Toprim domain 56 145 9.1E-24 T 13-10-2018 IPR006171 TOPRIM domain MADE_1013260 31f65a6c64206a2ac0aeca7f56719f53 172 TIGRFAM TIGR00615 recR: recombination protein RecR 1 170 4.8E-65 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 MADE_1013260 31f65a6c64206a2ac0aeca7f56719f53 172 SMART SM00493 54 139 2.5E-16 T 13-10-2018 IPR006171 TOPRIM domain MADE_1007175 90a2d0fbb991e3010172aa0b16100bc2 196 SUPERFAMILY SSF48498 74 187 1.41E-15 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MADE_1007175 90a2d0fbb991e3010172aa0b16100bc2 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 52 5.6E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1007175 90a2d0fbb991e3010172aa0b16100bc2 196 SUPERFAMILY SSF46689 5 75 2.67E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1007175 90a2d0fbb991e3010172aa0b16100bc2 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1007175 90a2d0fbb991e3010172aa0b16100bc2 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1007175 90a2d0fbb991e3010172aa0b16100bc2 196 Gene3D G3DSA:1.10.357.10 3 191 1.2E-34 T 13-10-2018 MADE_1009905 3c773b7b092951dc2013b137ec91e7f7 325 Pfam PF02780 Transketolase, C-terminal domain 195 312 4.3E-36 T 13-10-2018 IPR033248 Transketolase, C-terminal domain MADE_1009905 3c773b7b092951dc2013b137ec91e7f7 325 Gene3D G3DSA:3.40.50.970 1 193 2.3E-89 T 13-10-2018 MADE_1009905 3c773b7b092951dc2013b137ec91e7f7 325 SUPERFAMILY SSF52518 1 205 2.0E-71 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1009905 3c773b7b092951dc2013b137ec91e7f7 325 Gene3D G3DSA:3.40.50.920 194 324 8.9E-53 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1009905 3c773b7b092951dc2013b137ec91e7f7 325 SMART SM00861 4 180 1.1E-66 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1009905 3c773b7b092951dc2013b137ec91e7f7 325 SUPERFAMILY SSF52922 189 324 1.83E-40 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1009905 3c773b7b092951dc2013b137ec91e7f7 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 179 1.3E-50 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1004810 21469454b7d6a7b57b2adc7db1026824 340 Gene3D G3DSA:3.90.25.10 195 330 4.2E-147 T 13-10-2018 MADE_1004810 21469454b7d6a7b57b2adc7db1026824 340 SUPERFAMILY SSF51735 1 336 1.92E-100 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1004810 21469454b7d6a7b57b2adc7db1026824 340 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 326 1.2E-61 T 13-10-2018 IPR016040 NAD(P)-binding domain MADE_1004810 21469454b7d6a7b57b2adc7db1026824 340 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 336 3.3E-142 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 MADE_1004810 21469454b7d6a7b57b2adc7db1026824 340 Gene3D G3DSA:3.40.50.720 4 275 4.2E-147 T 13-10-2018 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 PRINTS PR00207 Flagellin signature 111 134 7.2E-25 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 PRINTS PR00207 Flagellin signature 76 95 7.2E-25 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 PRINTS PR00207 Flagellin signature 37 54 7.2E-25 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 SUPERFAMILY SSF64518 1 318 3.53E-91 T 13-10-2018 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.4E-42 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 Gene3D G3DSA:1.20.1330.10 190 280 4.6E-14 T 13-10-2018 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 Gene3D G3DSA:1.20.1330.10 44 189 3.7E-46 T 13-10-2018 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 Gene3D G3DSA:1.20.120.2000 281 319 2.3E-10 T 13-10-2018 MADE_1005770 a15efb7261e51bf77a5a33dedbb7dedf 319 Pfam PF00700 Bacterial flagellin C-terminal helical region 236 318 1.7E-22 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 Pfam PF03459 TOBE domain 289 351 1.9E-9 T 13-10-2018 IPR005116 Transport-associated OB, type 1 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 Gene3D G3DSA:2.40.50.140 233 351 6.1E-11 T 13-10-2018 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 Gene3D G3DSA:3.40.50.300 5 229 7.5E-57 T 13-10-2018 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 Pfam PF00005 ABC transporter 15 156 9.6E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 6 350 1.9E-107 T 13-10-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 SMART SM00382 22 206 1.5E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1019285 e3a4f9009a800131609faed0a418b187 352 Gene3D G3DSA:2.40.50.100 275 348 6.1E-11 T 13-10-2018 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 SUPERFAMILY SSF52540 11 222 1.55E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019285 e3a4f9009a800131609faed0a418b187 352 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1019285 e3a4f9009a800131609faed0a418b187 352 SUPERFAMILY SSF50331 233 351 1.56E-15 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 Gene3D G3DSA:3.40.50.620 5 217 3.9E-74 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 Gene3D G3DSA:3.10.290.10 327 398 1.6E-19 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 398 48.346 T 13-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 Pfam PF00579 tRNA synthetases class I (W and Y) 31 317 4.8E-79 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 8.4E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 8.4E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 8.4E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 8.4E-24 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 SUPERFAMILY SSF55174 320 398 1.23E-18 T 13-10-2018 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 8 398 4.6E-126 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 Gene3D G3DSA:1.10.240.10 218 326 8.3E-35 T 13-10-2018 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 SUPERFAMILY SSF52374 8 315 5.41E-96 T 13-10-2018 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 Pfam PF01479 S4 domain 342 374 8.1E-5 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1015840 500be3a9a8f7267667c1764e6ddcfaa8 399 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1015560 9e014377f5dbbc56204ee51f52a71433 307 Gene3D G3DSA:3.40.50.1100 14 304 1.5E-51 T 13-10-2018 MADE_1015560 9e014377f5dbbc56204ee51f52a71433 307 PIRSF PIRSF006278 3 307 4.1E-54 T 13-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase MADE_1015560 9e014377f5dbbc56204ee51f52a71433 307 Gene3D G3DSA:3.40.50.1100 47 147 1.5E-51 T 13-10-2018 MADE_1015560 9e014377f5dbbc56204ee51f52a71433 307 SUPERFAMILY SSF53686 11 305 2.16E-39 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MADE_1015560 9e014377f5dbbc56204ee51f52a71433 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 28 301 9.8E-14 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 Gene3D G3DSA:3.40.50.300 1 213 1.5E-78 T 13-10-2018 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 PRINTS PR00094 Adenylate kinase signature 173 187 3.1E-36 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 PRINTS PR00094 Adenylate kinase signature 81 97 3.1E-36 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 PRINTS PR00094 Adenylate kinase signature 4 17 3.1E-36 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 PRINTS PR00094 Adenylate kinase signature 32 46 3.1E-36 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 PRINTS PR00094 Adenylate kinase signature 156 171 3.1E-36 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 Pfam PF05191 Adenylate kinase, active site lid 123 158 7.9E-15 T 13-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 Pfam PF00406 Adenylate kinase 5 185 1.9E-58 T 13-10-2018 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 211 5.0E-75 T 13-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 SUPERFAMILY SSF52540 1 209 6.43E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 13-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MADE_1013250 a701da2b782cb8f20c359cf08d558b65 214 Hamap MF_00235 Adenylate kinase [adk]. 1 214 50.997 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 MADE_000001023465 f795f81435a320e7c2f3ffe3b9fb8222 322 Gene3D G3DSA:3.40.1190.20 1 322 4.9E-92 T 13-10-2018 IPR029056 Ribokinase-like MADE_000001023465 f795f81435a320e7c2f3ffe3b9fb8222 322 Pfam PF00294 pfkB family carbohydrate kinase 2 316 1.5E-59 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB MADE_000001023465 f795f81435a320e7c2f3ffe3b9fb8222 322 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 254 267 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MADE_000001023465 f795f81435a320e7c2f3ffe3b9fb8222 322 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 MADE_000001023465 f795f81435a320e7c2f3ffe3b9fb8222 322 SUPERFAMILY SSF53613 1 320 3.43E-76 T 13-10-2018 IPR029056 Ribokinase-like MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:3.30.70.1430 40 798 0.0 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:1.20.1640.10 502 1004 0.0 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:3.30.70.1430 556 651 0.0 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:3.30.70.1320 134 326 0.0 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Pfam PF00873 AcrB/AcrD/AcrF family 4 1006 1.1E-299 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 607 621 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 4.0E-80 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:1.20.1640.10 10 501 0.0 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 SUPERFAMILY SSF82714 182 266 2.49E-16 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 SUPERFAMILY SSF82693 554 654 5.75E-14 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 SUPERFAMILY SSF82693 137 324 2.41E-21 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 SUPERFAMILY SSF82714 702 787 1.7E-16 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:3.30.2090.10 178 269 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 SUPERFAMILY SSF82866 291 489 4.97E-48 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:3.30.70.1440 652 847 0.0 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 SUPERFAMILY SSF82866 789 1009 2.88E-48 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 SUPERFAMILY SSF82693 40 134 7.46E-28 T 13-10-2018 MADE_1008795 b37f9838c5ef45ced87b6c7cb9c95b8c 1035 Gene3D G3DSA:3.30.2090.10 701 790 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1018075 50b936ddc92a0a326fe1e203aec20ff0 488 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 8.3E-181 T 13-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MADE_1018075 50b936ddc92a0a326fe1e203aec20ff0 488 SUPERFAMILY SSF143968 323 486 9.68E-68 T 13-10-2018 MADE_1018075 50b936ddc92a0a326fe1e203aec20ff0 488 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 431 2.0E-175 T 13-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MADE_1018075 50b936ddc92a0a326fe1e203aec20ff0 488 Gene3D G3DSA:3.40.1670.10 337 454 1.1E-52 T 13-10-2018 MADE_1018075 50b936ddc92a0a326fe1e203aec20ff0 488 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 73.46 T 13-10-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 MADE_1018075 50b936ddc92a0a326fe1e203aec20ff0 488 Gene3D G3DSA:1.20.5.570 455 488 3.5E-14 T 13-10-2018 MADE_1018075 50b936ddc92a0a326fe1e203aec20ff0 488 SUPERFAMILY SSF50475 3 322 9.42E-130 T 13-10-2018 MADE_1001830 86e21ddcb6642e0da2d7d9d43306221d 136 Pfam PF01219 Prokaryotic diacylglycerol kinase 39 131 1.5E-26 T 13-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MADE_1001830 86e21ddcb6642e0da2d7d9d43306221d 136 Gene3D G3DSA:1.10.3830.10 16 136 1.3E-29 T 13-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 Pfam PF09334 tRNA synthetases class I (M) 34 421 1.5E-155 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 52 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 PRINTS PR01041 Methionyl-tRNA synthetase signature 36 49 2.4E-22 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 PRINTS PR01041 Methionyl-tRNA synthetase signature 277 288 2.4E-22 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 PRINTS PR01041 Methionyl-tRNA synthetase signature 68 82 2.4E-22 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 PRINTS PR01041 Methionyl-tRNA synthetase signature 409 420 2.4E-22 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 PRINTS PR01041 Methionyl-tRNA synthetase signature 116 127 2.4E-22 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 PRINTS PR01041 Methionyl-tRNA synthetase signature 316 331 2.4E-22 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 SUPERFAMILY SSF47323 415 572 5.61E-45 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 Pfam PF01588 Putative tRNA binding domain 607 699 4.0E-24 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 34 560 3.5E-182 T 13-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 Gene3D G3DSA:2.20.28.20 168 202 2.5E-154 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 SUPERFAMILY SSF50249 596 701 2.35E-32 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 568 702 1.4E-44 T 13-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 Gene3D G3DSA:2.40.50.140 591 702 8.3E-34 T 13-10-2018 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 SUPERFAMILY SSF57770 168 202 9.16E-12 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 Hamap MF_00098 Methionine--tRNA ligase [metG]. 32 570 40.352 T 13-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 SUPERFAMILY SSF52374 31 412 6.97E-103 T 13-10-2018 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 Gene3D G3DSA:1.10.730.10 405 561 1.6E-34 T 13-10-2018 MADE_1010060 18334e75b09a4d6f37deaaa2a46a856d 702 Gene3D G3DSA:3.40.50.620 34 404 2.5E-154 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1003915 164388a0f6021430d91722d80ce88adc 522 Pfam PF00501 AMP-binding enzyme 18 431 1.2E-94 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_1003915 164388a0f6021430d91722d80ce88adc 522 SUPERFAMILY SSF56801 7 521 9.42E-139 T 13-10-2018 MADE_1003915 164388a0f6021430d91722d80ce88adc 522 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 13-10-2018 IPR020845 AMP-binding, conserved site MADE_1003915 164388a0f6021430d91722d80ce88adc 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 513 2.2E-19 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MADE_1003915 164388a0f6021430d91722d80ce88adc 522 Gene3D G3DSA:3.30.300.310 428 522 1.4E-32 T 13-10-2018 MADE_1003915 164388a0f6021430d91722d80ce88adc 522 Gene3D G3DSA:3.40.50.12780 2 427 3.5E-107 T 13-10-2018 MADE_1004790 b699a001cd895009a4a24e6defb91036 219 SUPERFAMILY SSF52833 42 188 1.01E-26 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1004790 b699a001cd895009a4a24e6defb91036 219 Gene3D G3DSA:3.40.30.10 24 195 7.8E-34 T 13-10-2018 MADE_1004790 b699a001cd895009a4a24e6defb91036 219 Pfam PF08534 Redoxin 39 173 6.7E-16 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MADE_1004790 b699a001cd895009a4a24e6defb91036 219 ProSitePatterns PS00194 Thioredoxin family active site. 67 85 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_000001021230 672d2ca335616237023d2507d781cd0e 351 Gene3D G3DSA:3.40.50.10800 31 322 1.3E-96 T 13-10-2018 MADE_000001021230 672d2ca335616237023d2507d781cd0e 351 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 27 342 6.4E-116 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MADE_000001021230 672d2ca335616237023d2507d781cd0e 351 Pfam PF02445 Quinolinate synthetase A protein 32 340 7.1E-104 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MADE_000001021230 672d2ca335616237023d2507d781cd0e 351 Gene3D G3DSA:3.40.50.10800 115 339 1.3E-96 T 13-10-2018 MADE_000001021230 672d2ca335616237023d2507d781cd0e 351 SUPERFAMILY SSF142754 28 341 6.28E-109 T 13-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MADE_000001021230 672d2ca335616237023d2507d781cd0e 351 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 347 67.95 T 13-10-2018 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 MADE_000001021230 672d2ca335616237023d2507d781cd0e 351 Gene3D G3DSA:3.40.50.10800 200 295 1.3E-96 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 SUPERFAMILY SSF82866 291 491 1.24E-38 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 SUPERFAMILY SSF82714 185 265 1.31E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 SUPERFAMILY SSF82693 139 323 3.49E-17 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:3.30.70.1430 554 657 7.4E-258 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 SUPERFAMILY SSF82866 795 1020 8.37E-50 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 SUPERFAMILY SSF82693 42 125 1.91E-18 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:3.30.70.1430 42 808 7.4E-258 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 PRINTS PR00702 Acriflavin resistance protein family signature 537 554 8.1E-37 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:3.30.70.1440 658 858 7.4E-258 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:1.20.1640.10 497 1013 7.4E-258 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:3.30.2090.10 180 271 7.4E-258 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Pfam PF00873 AcrB/AcrD/AcrF family 5 1015 9.4E-264 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 2 1020 1.8E-260 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 SUPERFAMILY SSF82714 711 796 8.76E-6 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:3.30.2090.10 709 800 7.4E-258 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:3.30.70.1320 135 324 7.4E-258 T 13-10-2018 MADE_1000505 eb2f83cbdd2bba66abfaf373850867bc 1022 Gene3D G3DSA:1.20.1640.10 15 496 7.4E-258 T 13-10-2018 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Pfam PF14559 Tetratricopeptide repeat 319 374 8.6E-6 T 13-10-2018 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Gene3D G3DSA:1.25.40.10 129 425 6.7E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Gene3D G3DSA:1.25.40.10 551 918 1.9E-33 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SUPERFAMILY SSF48452 32 236 1.95E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 406 438 270.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 710 743 260.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 473 506 27.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 810 843 5.1 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 507 540 300.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 271 304 84.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 609 642 250.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 66 99 20.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SMART SM00028 32 65 190.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SUPERFAMILY SSF48452 181 364 2.31E-17 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Gene3D G3DSA:1.25.40.10 35 116 1.4E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Gene3D G3DSA:1.25.40.10 426 546 1.4E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Pfam PF13432 Tetratricopeptide repeat 790 837 0.0032 T 13-10-2018 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Pfam PF13432 Tetratricopeptide repeat 209 265 0.0078 T 13-10-2018 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SUPERFAMILY SSF48452 717 869 5.22E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 Pfam PF13414 TPR repeat 42 79 2.2E-7 T 13-10-2018 MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 TIGRFAM TIGR02917 PEP_TPR_lipo: putative PEP-CTERM system TPR-repeat lipoprotein 15 902 3.1E-149 T 13-10-2018 IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative MADE_1003530 4eb9f852c9446cc670793aa1d49fe20c 924 SUPERFAMILY SSF48452 449 676 1.39E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1007895 597aac2d17e86feee02efe670abc6398 166 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 60 4.4E-6 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MADE_1007895 597aac2d17e86feee02efe670abc6398 166 Pfam PF01799 [2Fe-2S] binding domain 75 145 2.2E-25 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MADE_1007895 597aac2d17e86feee02efe670abc6398 166 Gene3D G3DSA:3.10.20.30 1 78 8.4E-25 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1007895 597aac2d17e86feee02efe670abc6398 166 Gene3D G3DSA:1.10.150.120 79 154 1.5E-24 T 13-10-2018 MADE_1007895 597aac2d17e86feee02efe670abc6398 166 SUPERFAMILY SSF47741 75 150 3.27E-29 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MADE_1007895 597aac2d17e86feee02efe670abc6398 166 SUPERFAMILY SSF54292 2 80 9.04E-23 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_1007895 597aac2d17e86feee02efe670abc6398 166 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 SUPERFAMILY SSF82693 51 143 1.99E-15 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 SUPERFAMILY SSF82866 318 506 1.83E-31 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 SUPERFAMILY SSF82714 730 812 4.84E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:3.30.70.1430 51 830 3.5E-215 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:3.30.70.1440 683 877 3.5E-215 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:3.30.2090.10 195 287 3.5E-215 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Pfam PF00873 AcrB/AcrD/AcrF family 18 1035 6.6E-138 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:3.30.70.1430 580 682 3.5E-215 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 49 67 1.8E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 563 580 1.8E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 346 369 1.8E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 479 502 1.8E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 400 424 1.8E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 454 477 1.8E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 21 45 1.8E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:1.20.1640.10 26 523 3.5E-215 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 SUPERFAMILY SSF82693 166 338 3.66E-5 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:3.30.70.1320 148 340 3.5E-215 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 SUPERFAMILY SSF82866 819 1042 3.4E-32 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 SUPERFAMILY SSF82714 200 281 2.09E-11 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:1.20.1640.10 524 1033 3.5E-215 T 13-10-2018 MADE_1002465 5813fe2cae869a69d53e9ea10a8a3a0e 1048 Gene3D G3DSA:3.30.2090.10 731 822 3.5E-215 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013990 35bd2abf5c8b034883bef610cb0b1ce0 130 SUPERFAMILY SSF56047 2 129 5.1E-45 T 13-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013990 35bd2abf5c8b034883bef610cb0b1ce0 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 30.542 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013990 35bd2abf5c8b034883bef610cb0b1ce0 130 Pfam PF00410 Ribosomal protein S8 5 129 1.4E-47 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013990 35bd2abf5c8b034883bef610cb0b1ce0 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013990 35bd2abf5c8b034883bef610cb0b1ce0 130 Gene3D G3DSA:3.30.1370.30 2 72 2.1E-26 T 13-10-2018 MADE_1013990 35bd2abf5c8b034883bef610cb0b1ce0 130 Gene3D G3DSA:3.30.1490.10 73 130 3.6E-23 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1301 2.3E-78 T 13-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:2.40.50.100 948 1022 8.4E-28 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 SMART SM00663 235 514 1.7E-182 T 13-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1361 18.993 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:2.40.50.100 1023 1112 1.7E-10 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:1.10.40.90 374 416 1.9E-21 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 9.3E-20 T 13-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:2.40.50.100 1137 1200 3.4E-63 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:1.10.1790.20 1121 1299 3.4E-63 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 SUPERFAMILY SSF64484 16 1356 0.0 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Pfam PF00623 RNA polymerase Rpb1, domain 2 392 485 4.1E-27 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 383 1.7E-7 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1025 0.0 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 6.6E-87 T 13-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:1.10.132.30 641 790 6.5E-67 T 13-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:1.10.150.390 1301 1363 9.1E-29 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Gene3D G3DSA:1.10.274.100 490 640 9.7E-41 T 13-10-2018 MADE_000001023295 84bd50c2ef3ab82ffbe2f1854a027935 1390 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 2.1E-29 T 13-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 Gene3D G3DSA:3.90.226.10 2 317 1.5E-116 T 13-10-2018 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 199 208 1.3E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 155 168 1.3E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 136 152 1.3E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 171 184 1.3E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 90 101 1.3E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 115 133 1.3E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 318 50.16 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 SUPERFAMILY SSF52096 6 317 4.64E-102 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 318 1.5E-160 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1005395 9124829e4a662582ba49e40d77fd98f8 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 150 8.1E-63 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1002975 512179ded242225c017359effdb2351c 509 Pfam PF07075 Protein of unknown function (DUF1343) 132 505 1.1E-117 T 13-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 MADE_1002975 512179ded242225c017359effdb2351c 509 Gene3D G3DSA:3.40.50.12170 121 508 3.4E-125 T 13-10-2018 MADE_1019465 63091f7196adb83f5248dd439312728d 346 Gene3D G3DSA:3.40.50.720 3 316 6.4E-111 T 13-10-2018 MADE_1019465 63091f7196adb83f5248dd439312728d 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 131 223 3.2E-14 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MADE_1019465 63091f7196adb83f5248dd439312728d 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 119 7.3E-21 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MADE_1019465 63091f7196adb83f5248dd439312728d 346 SUPERFAMILY SSF51735 5 165 4.67E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1019465 63091f7196adb83f5248dd439312728d 346 SUPERFAMILY SSF55347 127 288 5.89E-30 T 13-10-2018 MADE_1019465 63091f7196adb83f5248dd439312728d 346 Gene3D G3DSA:3.30.360.10 124 330 6.4E-111 T 13-10-2018 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 SUPERFAMILY SSF52096 4 290 4.59E-49 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 299 475 4.9E-66 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 480 573 4.5E-26 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 611 698 1.5E-7 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 188 2.6E-26 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 SUPERFAMILY SSF48179 605 701 9.35E-21 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 SUPERFAMILY SSF51735 296 476 1.92E-59 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 SUPERFAMILY SSF48179 480 582 6.12E-25 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 Gene3D G3DSA:3.40.50.720 297 480 1.3E-69 T 13-10-2018 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 Gene3D G3DSA:1.10.1040.50 482 707 5.6E-72 T 13-10-2018 MADE_1008780 9258dedfb2fc9066e9d8cc7fda228f3c 708 Gene3D G3DSA:3.90.226.10 2 294 1.2E-66 T 13-10-2018 MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 Gene3D G3DSA:3.40.630.10 37 412 2.7E-133 T 13-10-2018 MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 38 417 2.2E-106 T 13-10-2018 IPR017439 Amidohydrolase GO:0016787 MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 Pfam PF07687 Peptidase dimerisation domain 223 318 6.7E-11 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 SUPERFAMILY SSF53187 27 430 1.01E-83 T 13-10-2018 MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 Pfam PF01546 Peptidase family M20/M25/M40 95 424 8.3E-31 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 SUPERFAMILY SSF55031 221 327 9.94E-30 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 PIRSF PIRSF005962 22 432 4.3E-119 T 13-10-2018 IPR017439 Amidohydrolase GO:0016787 MADE_1002865 21f4c4d7ae5615aded833db2254fe0db 432 Gene3D G3DSA:3.30.70.360 218 335 2.7E-133 T 13-10-2018 MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 Gene3D G3DSA:3.40.50.720 18 308 5.9E-102 T 13-10-2018 MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 SUPERFAMILY SSF52283 2 138 8.32E-28 T 13-10-2018 MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 308 7.2E-21 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 SUPERFAMILY SSF51735 103 287 4.34E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 286 2.6E-50 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MADE_1020190 042311aac396d27f97f44b0fd299f92a 310 Gene3D G3DSA:3.40.50.720 99 285 5.9E-102 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Gene3D G3DSA:3.30.70.100 89 160 3.0E-13 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Pfam PF00702 haloacid dehalogenase-like hydrolase 505 705 6.9E-26 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 SUPERFAMILY SSF81665 265 502 9.55E-11 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Gene3D G3DSA:3.40.1110.10 519 624 3.7E-63 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 281 794 1.0E-112 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 663 679 8.8E-8 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 691 707 8.8E-8 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 722 747 8.8E-8 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 231 793 3.1E-141 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 714 726 1.3E-22 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 509 523 1.3E-22 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 361 375 1.3E-22 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 691 710 1.3E-22 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 5 89 6.0E-25 T 13-10-2018 IPR021993 Putative metal-binding domain of cation transport ATPase MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 283 770 1.5E-71 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 SUPERFAMILY SSF55008 91 166 8.9E-16 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 SUPERFAMILY SSF56784 507 790 3.02E-46 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 249 793 1.1E-154 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 SUPERFAMILY SSF81653 321 410 3.4E-23 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 511 517 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Gene3D G3DSA:3.40.50.1000 489 730 3.7E-63 T 13-10-2018 IPR023214 HAD superfamily MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 ProSitePatterns PS01047 Heavy-metal-associated domain. 100 129 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Pfam PF00403 Heavy-metal-associated domain 99 157 1.5E-10 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Pfam PF00122 E1-E2 ATPase 313 489 6.6E-48 T 13-10-2018 MADE_1010445 cdab633fd4855ca36ca12b8782396603 796 Gene3D G3DSA:2.70.150.20 305 415 1.1E-30 T 13-10-2018 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 Gene3D G3DSA:3.40.50.2300 167 308 1.4E-25 T 13-10-2018 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 SMART SM00260 17 153 2.5E-21 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 Pfam PF01584 CheW-like domain 21 155 2.2E-33 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 PIRSF PIRSF002867 1 307 1.3E-105 T 13-10-2018 IPR024181 Chemotaxis response regulator CheV MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 Pfam PF00072 Response regulator receiver domain 181 300 8.0E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 Gene3D G3DSA:2.40.50.180 39 153 4.4E-27 T 13-10-2018 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 SUPERFAMILY SSF52172 177 304 3.98E-25 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 SMART SM00448 179 300 4.5E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 SUPERFAMILY SSF50341 16 157 6.93E-35 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1005695 918c896ba039acc6d62023155a60a6fa 309 Gene3D G3DSA:2.30.30.40 24 147 4.4E-27 T 13-10-2018 MADE_1012620 bef90e8000911699c4e297f337150d49 154 SUPERFAMILY SSF54523 10 139 3.14E-19 T 13-10-2018 MADE_1012620 bef90e8000911699c4e297f337150d49 154 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 1.4E-10 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012620 bef90e8000911699c4e297f337150d49 154 ProSitePatterns PS00018 EF-hand calcium-binding domain. 138 150 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site MADE_1012620 bef90e8000911699c4e297f337150d49 154 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012620 bef90e8000911699c4e297f337150d49 154 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 30 9.0E-10 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012620 bef90e8000911699c4e297f337150d49 154 Gene3D G3DSA:3.30.700.10 10 154 1.4E-20 T 13-10-2018 MADE_1012620 bef90e8000911699c4e297f337150d49 154 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 31 122 1.4E-13 T 13-10-2018 IPR031982 Type IV minor pilin ComP MADE_1009165 62165a147885737e65dfceb7d78898fb 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 138 5.0E-51 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 MADE_1009165 62165a147885737e65dfceb7d78898fb 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 14 156 1.9E-53 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 MADE_1009165 62165a147885737e65dfceb7d78898fb 159 ProSitePatterns PS01317 SsrA-binding protein. 32 44 - T 13-10-2018 IPR020081 SsrA-binding protein, conserved site MADE_1009165 62165a147885737e65dfceb7d78898fb 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 70.081 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 MADE_1009165 62165a147885737e65dfceb7d78898fb 159 Pfam PF01668 SmpB protein 14 157 4.3E-58 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 MADE_1009165 62165a147885737e65dfceb7d78898fb 159 SUPERFAMILY SSF74982 8 138 3.14E-48 T 13-10-2018 IPR023620 Small protein B MADE_1009165 62165a147885737e65dfceb7d78898fb 159 Gene3D G3DSA:2.40.280.10 6 134 1.2E-45 T 13-10-2018 IPR023620 Small protein B MADE_1007130 5505e70a58dc67eecfee8a6388b89c31 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 59 3.0E-14 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MADE_1007130 5505e70a58dc67eecfee8a6388b89c31 82 SUPERFAMILY SSF143120 1 65 4.19E-13 T 13-10-2018 IPR036165 YefM-like superfamily MADE_1007130 5505e70a58dc67eecfee8a6388b89c31 82 Gene3D G3DSA:3.40.1620.40 1 51 2.2E-8 T 13-10-2018 MADE_1007130 5505e70a58dc67eecfee8a6388b89c31 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 49 2.0E-10 T 13-10-2018 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 Gene3D G3DSA:3.30.1360.70 1 105 8.0E-31 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 SMART SM00836 459 576 2.0E-33 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 302 323 3.9E-25 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 113 128 3.9E-25 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 152 165 3.9E-25 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 144 3.9E-25 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 SUPERFAMILY SSF55190 1 95 9.68E-22 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 Gene3D G3DSA:1.10.730.10 453 576 6.5E-34 T 13-10-2018 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 121 132 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 Gene3D G3DSA:3.40.50.620 107 452 4.5E-108 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 SMART SM01016 5 86 6.8E-29 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 Pfam PF00750 tRNA synthetases class I (R) 103 445 1.0E-132 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 576 6.8E-173 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 SUPERFAMILY SSF52374 109 452 8.28E-89 T 13-10-2018 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 576 26.899 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 9 86 4.9E-23 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 SUPERFAMILY SSF47323 453 576 7.85E-33 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1006385 98daa80cb8570644c7d88105db162c4e 576 Pfam PF05746 DALR anticodon binding domain 459 576 2.8E-29 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MADE_1001870 69cd9b1bae31e16c754382e53b5f9abc 229 SMART SM00448 1 112 1.0E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1001870 69cd9b1bae31e16c754382e53b5f9abc 229 SUPERFAMILY SSF52172 1 175 4.13E-36 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1001870 69cd9b1bae31e16c754382e53b5f9abc 229 Gene3D G3DSA:3.40.50.2300 1 124 3.7E-34 T 13-10-2018 MADE_1001870 69cd9b1bae31e16c754382e53b5f9abc 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 220 2.2E-12 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1001870 69cd9b1bae31e16c754382e53b5f9abc 229 SMART SM00862 146 221 3.1E-9 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1001870 69cd9b1bae31e16c754382e53b5f9abc 229 Pfam PF00072 Response regulator receiver domain 3 112 3.9E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1001870 69cd9b1bae31e16c754382e53b5f9abc 229 Gene3D G3DSA:1.10.10.10 125 229 7.8E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1018395 c7b59c8caf8168552350f6d8dafd1346 192 Pfam PF04222 Protein of unknown function (DUF416) 8 191 1.2E-60 T 13-10-2018 IPR007338 Protein of unknown function DUF416 MADE_1018395 c7b59c8caf8168552350f6d8dafd1346 192 Gene3D G3DSA:1.20.1590.10 2 192 5.5E-66 T 13-10-2018 IPR023381 YP001051499.1-like domain superfamily MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 Pfam PF03466 LysR substrate binding domain 90 287 2.3E-11 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.0E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 2 292 2.1E-86 T 13-10-2018 IPR017685 HTH-type transcriptional regulator ArgP MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 Gene3D G3DSA:1.10.10.10 1 81 9.9E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 Gene3D G3DSA:3.40.190.290 85 293 4.0E-58 T 13-10-2018 MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 SUPERFAMILY SSF53850 90 290 4.34E-18 T 13-10-2018 MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 SUPERFAMILY SSF46785 1 108 4.09E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1000870 123d47bc174b23d368f3b591c696a2a1 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.7E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 SMART SM00267 130 305 1.9E-46 T 13-10-2018 IPR000160 GGDEF domain MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 Gene3D G3DSA:3.30.70.270 134 305 2.9E-47 T 13-10-2018 MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 SMART SM00448 12 124 4.4E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 SUPERFAMILY SSF52172 12 138 3.56E-36 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 Gene3D G3DSA:3.40.50.2300 4 133 1.0E-34 T 13-10-2018 MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 SUPERFAMILY SSF55073 146 303 3.14E-39 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 Pfam PF00990 Diguanylate cyclase, GGDEF domain 142 303 9.0E-43 T 13-10-2018 IPR000160 GGDEF domain MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 137 304 2.9E-44 T 13-10-2018 IPR000160 GGDEF domain MADE_1007985 a066c842b7c3bdeb05673828412e564c 306 Pfam PF00072 Response regulator receiver domain 14 124 1.7E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 Gene3D G3DSA:3.90.79.10 1 144 8.9E-36 T 13-10-2018 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 SUPERFAMILY SSF55811 3 141 1.35E-24 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 PRINTS PR01404 DATP pyrophosphohydrolase signature 19 40 1.4E-17 T 13-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 PRINTS PR01404 DATP pyrophosphohydrolase signature 98 119 1.4E-17 T 13-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 PRINTS PR01404 DATP pyrophosphohydrolase signature 70 89 1.4E-17 T 13-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 PRINTS PR01404 DATP pyrophosphohydrolase signature 125 138 1.4E-17 T 13-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 MADE_000001021165 3c22a221c897298568015a98b85d3b3b 146 Pfam PF00293 NUDIX domain 5 137 1.3E-18 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 204 4.5E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 Pfam PF00072 Response regulator receiver domain 4 116 1.3E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 SUPERFAMILY SSF46894 141 208 7.82E-18 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 Gene3D G3DSA:3.40.50.12740 2 210 7.7E-47 T 13-10-2018 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 SMART SM00448 2 116 7.2E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 6.0E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 6.0E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 6.0E-11 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 SUPERFAMILY SSF52172 1 163 8.11E-25 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1010905 cb7942a7b2470fa08d0ebb26e12bca87 211 SMART SM00421 148 205 2.4E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001022525 565a6fbfa8fdf9fb63641fbd2e5ee18c 854 Gene3D G3DSA:3.40.50.300 478 660 8.3E-6 T 13-10-2018 MADE_1011595 12db9b059c307af3d702175093579bec 58 PIRSF PIRSF036466 1 55 8.7E-21 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 MADE_1011595 12db9b059c307af3d702175093579bec 58 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 3.1E-14 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 MADE_1011595 12db9b059c307af3d702175093579bec 58 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 48 20.288 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 MADE_1000960 92c1577fa5a6c07914262b82530e8916 222 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 75 5.1E-15 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1000960 92c1577fa5a6c07914262b82530e8916 222 Gene3D G3DSA:3.40.30.10 1 83 1.3E-31 T 13-10-2018 MADE_1000960 92c1577fa5a6c07914262b82530e8916 222 Gene3D G3DSA:1.20.1050.10 85 212 4.2E-25 T 13-10-2018 MADE_1000960 92c1577fa5a6c07914262b82530e8916 222 SUPERFAMILY SSF47616 85 217 1.07E-20 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1000960 92c1577fa5a6c07914262b82530e8916 222 SUPERFAMILY SSF52833 1 77 3.34E-17 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1000960 92c1577fa5a6c07914262b82530e8916 222 Pfam PF00043 Glutathione S-transferase, C-terminal domain 148 207 5.4E-7 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal MADE_1001900 05538e2d14091f369e533c2d84142afd 83 Gene3D G3DSA:3.10.450.50 1 83 4.2E-18 T 13-10-2018 MADE_1001900 05538e2d14091f369e533c2d84142afd 83 SUPERFAMILY SSF54427 3 76 1.41E-13 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1001900 05538e2d14091f369e533c2d84142afd 83 Pfam PF13474 SnoaL-like domain 16 76 1.2E-5 T 13-10-2018 IPR037401 SnoaL-like domain MADE_1006275 d850cda768d20351e33044b4044ae5be 423 Gene3D G3DSA:1.25.40.10 87 264 1.9E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006275 d850cda768d20351e33044b4044ae5be 423 Pfam PF13432 Tetratricopeptide repeat 307 367 3.1E-4 T 13-10-2018 MADE_1006275 d850cda768d20351e33044b4044ae5be 423 Gene3D G3DSA:1.25.40.10 265 400 1.1E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006275 d850cda768d20351e33044b4044ae5be 423 SMART SM00028 301 334 19.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006275 d850cda768d20351e33044b4044ae5be 423 SMART SM00028 335 367 160.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006275 d850cda768d20351e33044b4044ae5be 423 SMART SM00028 161 194 1.2 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006275 d850cda768d20351e33044b4044ae5be 423 SUPERFAMILY SSF48452 133 395 2.15E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 SUPERFAMILY SSF52374 4 156 1.82E-46 T 13-10-2018 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 Gene3D G3DSA:3.40.50.620 1 162 1.9E-58 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.4E-53 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.4E-53 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.4E-53 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.4E-53 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.4E-53 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 69 7.0E-5 T 13-10-2018 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 6.9E-59 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 4.2E-21 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 Pfam PF01467 Cytidylyltransferase-like 6 134 3.3E-25 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MADE_1000285 9b9e360cc28d4e8229f74431506deac7 162 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 35.995 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 MADE_1004905 a59411ebd0718744c2ddb5bf61c010b7 181 Pfam PF07348 Syd protein (SUKH-2) 7 178 1.0E-60 T 13-10-2018 IPR009948 Syd GO:0009898 MADE_1004905 a59411ebd0718744c2ddb5bf61c010b7 181 Gene3D G3DSA:3.40.1580.20 1 179 2.1E-64 T 13-10-2018 IPR038228 Syd superfamily MADE_1004905 a59411ebd0718744c2ddb5bf61c010b7 181 Hamap MF_01104 Protein Syd [syd]. 3 180 31.415 T 13-10-2018 IPR009948 Syd GO:0009898 MADE_1006095 7da4f7bd82652045c1b658f69a05b7d2 153 Gene3D G3DSA:1.10.10.10 101 149 2.0E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006095 7da4f7bd82652045c1b658f69a05b7d2 153 Gene3D G3DSA:1.10.10.10 9 54 1.3E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006095 7da4f7bd82652045c1b658f69a05b7d2 153 Hamap MF_01114 Regulatory protein RecX [recX]. 5 153 12.992 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 MADE_1006095 7da4f7bd82652045c1b658f69a05b7d2 153 Pfam PF02631 RecX family 31 148 6.1E-26 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 MADE_1006095 7da4f7bd82652045c1b658f69a05b7d2 153 Gene3D G3DSA:1.10.10.10 56 99 4.9E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009750 ff9a45719b4c1a52d82a6d6eed1d54bb 335 SUPERFAMILY SSF51735 122 285 3.14E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009750 ff9a45719b4c1a52d82a6d6eed1d54bb 335 SMART SM00829 16 332 1.1E-28 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1009750 ff9a45719b4c1a52d82a6d6eed1d54bb 335 Gene3D G3DSA:3.40.50.720 131 302 3.1E-84 T 13-10-2018 MADE_1009750 ff9a45719b4c1a52d82a6d6eed1d54bb 335 Pfam PF13602 Zinc-binding dehydrogenase 195 332 1.0E-19 T 13-10-2018 MADE_1009750 ff9a45719b4c1a52d82a6d6eed1d54bb 335 Gene3D G3DSA:3.90.180.10 14 330 3.1E-84 T 13-10-2018 MADE_1009750 ff9a45719b4c1a52d82a6d6eed1d54bb 335 SUPERFAMILY SSF50129 4 156 2.43E-35 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1009750 ff9a45719b4c1a52d82a6d6eed1d54bb 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 98 1.0E-10 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00101 Aspartate carbamoyltransferase signature 235 244 6.3E-30 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00101 Aspartate carbamoyltransferase signature 86 95 6.3E-30 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00101 Aspartate carbamoyltransferase signature 47 69 6.3E-30 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00101 Aspartate carbamoyltransferase signature 140 157 6.3E-30 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00101 Aspartate carbamoyltransferase signature 302 316 6.3E-30 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 13 153 3.4E-47 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 12 320 2.7E-93 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 SUPERFAMILY SSF53671 7 322 8.64E-88 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 Gene3D G3DSA:3.40.50.1370 13 317 9.6E-103 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 1.0E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 280 1.0E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 141 152 1.0E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 286 309 1.0E-19 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 164 319 2.8E-23 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MADE_1002450 3ceb7ded5983e46ac137fecb9df5480b 342 Gene3D G3DSA:3.40.50.1370 141 308 9.6E-103 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MADE_000001021940 182d9c9aa150129c2bb7abbc5e1916bb 176 Pfam PF11086 Protein of unknown function (DUF2878) 9 161 4.6E-39 T 13-10-2018 IPR021306 Protein of unknown function DUF2878 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 Pfam PF14579 Helix-hairpin-helix motif 770 855 9.1E-15 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 Gene3D G3DSA:3.20.20.140 1 247 8.8E-35 T 13-10-2018 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 Pfam PF02811 PHP domain 8 100 2.1E-8 T 13-10-2018 IPR004013 PHP domain GO:0003824 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 SUPERFAMILY SSF89550 10 66 2.94E-5 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 3 1029 12.784 T 13-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 Pfam PF01336 OB-fold nucleic acid binding domain 938 1010 2.9E-7 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 SMART SM00481 4 73 9.1E-4 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 973 8.3E-160 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000185 c5ff22b97d5efdb6e413f48fd69b8bca 1029 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 270 695 2.0E-144 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1001390 5a249ee42dbc56308329333a95152759 90 Gene3D G3DSA:1.10.3880.10 1 90 9.2E-39 T 13-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 MADE_1001390 5a249ee42dbc56308329333a95152759 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 3.0E-32 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MADE_1001390 5a249ee42dbc56308329333a95152759 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.194 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MADE_1001390 5a249ee42dbc56308329333a95152759 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 1.2E-42 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MADE_1001390 5a249ee42dbc56308329333a95152759 90 PIRSF PIRSF029827 1 90 1.0E-42 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 MADE_1001390 5a249ee42dbc56308329333a95152759 90 SUPERFAMILY SSF111148 1 89 1.57E-39 T 13-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 200 216 - T 13-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 Gene3D G3DSA:3.90.79.10 232 354 1.3E-14 T 13-10-2018 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 SMART SM00478 43 198 1.1E-46 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 SUPERFAMILY SSF48150 8 233 2.83E-76 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 10 282 7.1E-114 T 13-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 200 216 3.0E-4 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 Pfam PF14815 NUDIX domain 244 352 6.9E-20 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 Gene3D G3DSA:1.10.340.30 25 136 5.0E-86 T 13-10-2018 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 39 173 3.3E-22 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 SUPERFAMILY SSF55811 228 354 4.06E-24 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 Pfam PF00633 Helix-hairpin-helix motif 103 131 2.5E-6 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 Gene3D G3DSA:1.10.1670.10 13 219 5.0E-86 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MADE_1001385 ab6c0660588422eefb7c9b6197deab13 355 SMART SM00525 199 219 2.5E-6 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 Gene3D G3DSA:3.30.70.270 135 306 4.1E-49 T 13-10-2018 MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 SMART SM00267 132 307 2.1E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 139 306 6.4E-40 T 13-10-2018 IPR000160 GGDEF domain MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 SUPERFAMILY SSF55073 148 304 3.37E-41 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 SUPERFAMILY SSF52172 13 159 7.26E-34 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 SMART SM00448 14 126 2.5E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 Pfam PF00072 Response regulator receiver domain 16 126 1.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 Gene3D G3DSA:3.40.50.2300 9 134 2.5E-33 T 13-10-2018 MADE_000001023075 e8a0846e80f67f9c780077c7abf53b4e 329 Pfam PF00990 Diguanylate cyclase, GGDEF domain 144 303 3.4E-40 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 SUPERFAMILY SSF47781 66 135 3.06E-20 T 13-10-2018 IPR010994 RuvA domain 2-like MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 SMART SM00278 108 127 0.06 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 SMART SM00278 73 92 85.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 205 1.7E-58 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 Pfam PF14520 Helix-hairpin-helix domain 72 130 3.1E-17 T 13-10-2018 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 Gene3D G3DSA:1.10.8.10 159 206 2.5E-19 T 13-10-2018 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 206 31.366 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 Gene3D G3DSA:2.40.50.140 1 66 3.8E-28 T 13-10-2018 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 Pfam PF07499 RuvA, C-terminal domain 161 204 1.9E-13 T 13-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 Pfam PF01330 RuvA N terminal domain 1 62 2.8E-22 T 13-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 Gene3D G3DSA:1.10.150.20 67 139 2.4E-25 T 13-10-2018 MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 SUPERFAMILY SSF50249 1 63 7.42E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001021175 79ed2f78f879f4c64b2d38405473d23a 206 SUPERFAMILY SSF46929 160 204 7.32E-11 T 13-10-2018 IPR036267 RuvA, C-terminal domain superfamily MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 SMART SM00838 607 695 1.5E-55 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Gene3D G3DSA:3.40.50.300 2 299 2.4E-115 T 13-10-2018 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Gene3D G3DSA:2.40.30.10 300 423 5.2E-50 T 13-10-2018 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 2.0E-17 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.0E-17 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 2.0E-17 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 2.0E-17 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 2.0E-17 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.5E-65 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Gene3D G3DSA:3.30.230.10 491 695 5.7E-93 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Pfam PF03764 Elongation factor G, domain IV 486 605 2.3E-50 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Gene3D G3DSA:3.30.70.240 611 682 5.7E-93 T 13-10-2018 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 SUPERFAMILY SSF54980 409 487 5.04E-25 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Pfam PF14492 Elongation Factor G, domain II 411 484 2.4E-34 T 13-10-2018 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 SUPERFAMILY SSF54980 610 698 7.67E-29 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 112.799 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 SUPERFAMILY SSF54211 486 606 3.03E-48 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Gene3D G3DSA:3.30.70.870 440 490 3.2E-26 T 13-10-2018 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 SMART SM00889 487 605 2.5E-79 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 SUPERFAMILY SSF50447 271 411 1.84E-34 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.8E-35 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 SUPERFAMILY SSF52540 6 288 1.11E-106 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Pfam PF03144 Elongation factor Tu domain 2 331 398 1.9E-16 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MADE_1018540 12a4e41ecc35ffdab06704c47de66335 700 Pfam PF00679 Elongation factor G C-terminus 607 693 5.6E-29 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 392 425 1.7E-9 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 Gene3D G3DSA:3.90.550.10 2 224 5.4E-66 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 Pfam PF12804 MobA-like NTP transferase domain 5 125 2.0E-21 T 13-10-2018 IPR025877 MobA-like NTP transferase MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 452 4.2E-194 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 400 428 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 SUPERFAMILY SSF53448 2 249 1.88E-61 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 449 42.346 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 263 296 2.8E-6 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 315 347 0.0011 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 Gene3D G3DSA:2.160.10.10 225 452 7.9E-68 T 13-10-2018 MADE_1019470 24f0f979287c3e980e47e136fe09d096 452 SUPERFAMILY SSF51161 252 435 2.28E-50 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1013845 fe8bcfa55e58102d4ea5e30b4ffc9b2e 381 SMART SM00672 151 365 2.4E-6 T 13-10-2018 IPR006598 Lipopolysaccharide-modifying protein MADE_1013845 fe8bcfa55e58102d4ea5e30b4ffc9b2e 381 Pfam PF05686 Glycosyl transferase family 90 247 362 8.7E-18 T 13-10-2018 IPR006598 Lipopolysaccharide-modifying protein MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Gene3D G3DSA:3.20.20.70 484 1172 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Pfam PF00310 Glutamine amidotransferases class-II 13 426 2.4E-173 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Pfam PF01645 Conserved region in glutamate synthase 794 1157 4.1E-151 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Pfam PF01493 GXGXG motif 1238 1423 2.6E-76 T 13-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Gene3D G3DSA:3.20.20.70 431 793 0.0 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Pfam PF04898 Glutamate synthase central domain 460 738 1.8E-101 T 13-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Gene3D G3DSA:2.160.20.60 1211 1480 1.0E-98 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 SUPERFAMILY SSF56235 13 429 6.88E-148 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 Gene3D G3DSA:3.60.20.10 13 546 0.0 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 SUPERFAMILY SSF69336 1214 1466 3.27E-86 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 MADE_000001022640 de29bb375f9b9d80f42d1e0aafe5366d 1488 SUPERFAMILY SSF51395 433 1194 4.48E-248 T 13-10-2018 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 Gene3D G3DSA:1.20.140.160 131 283 5.4E-15 T 13-10-2018 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 Gene3D G3DSA:1.10.601.10 7 124 5.3E-30 T 13-10-2018 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 SUPERFAMILY SSF88946 14 124 6.28E-40 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 Pfam PF04545 Sigma-70, region 4 229 279 2.9E-14 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 PIRSF PIRSF000770 9 284 5.3E-33 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 Pfam PF00140 Sigma-70 factor, region 1.2 21 47 2.5E-5 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 79 92 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 Pfam PF04542 Sigma-70 region 2 55 124 1.4E-16 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 SUPERFAMILY SSF88659 194 282 1.33E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 281 1.0E-32 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 284 52.208 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 16 283 6.3E-126 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 PRINTS PR00046 Major sigma-70 factor signature 252 267 1.1E-17 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 PRINTS PR00046 Major sigma-70 factor signature 79 92 1.1E-17 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 PRINTS PR00046 Major sigma-70 factor signature 233 245 1.1E-17 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1018360 5a2cfd88e0a619e0ecc2d9bb27c5b822 284 PRINTS PR00046 Major sigma-70 factor signature 267 278 1.1E-17 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 288 362 8.1E-13 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 SUPERFAMILY SSF46626 284 377 4.66E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 129 249 3.6E-36 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 197 245 - T 13-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 SUPERFAMILY SSF49503 121 321 1.83E-51 T 13-10-2018 IPR008972 Cupredoxin MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 43 261 1.3E-55 T 13-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 SUPERFAMILY SSF81464 33 123 1.8E-25 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 Gene3D G3DSA:2.60.40.420 126 265 2.2E-52 T 13-10-2018 IPR008972 Cupredoxin MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 PRINTS PR01166 Cytochrome c oxidase subunit II signature 125 144 2.2E-37 T 13-10-2018 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 PRINTS PR01166 Cytochrome c oxidase subunit II signature 172 193 2.2E-37 T 13-10-2018 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 PRINTS PR01166 Cytochrome c oxidase subunit II signature 103 123 2.2E-37 T 13-10-2018 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 PRINTS PR01166 Cytochrome c oxidase subunit II signature 196 216 2.2E-37 T 13-10-2018 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 PRINTS PR01166 Cytochrome c oxidase subunit II signature 234 251 2.2E-37 T 13-10-2018 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 PRINTS PR01166 Cytochrome c oxidase subunit II signature 216 233 2.2E-37 T 13-10-2018 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 PRINTS PR01166 Cytochrome c oxidase subunit II signature 91 103 2.2E-37 T 13-10-2018 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 Gene3D G3DSA:1.10.287.90 32 125 6.2E-24 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 35 114 8.1E-12 T 13-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020105 4086e44a93a4141109a932c7be95a09b 387 Gene3D G3DSA:1.10.760.10 269 387 7.8E-30 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1007975 b73fdb82f648c649b67c4dd4bfacfef1 98 Pfam PF00072 Response regulator receiver domain 8 93 4.7E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007975 b73fdb82f648c649b67c4dd4bfacfef1 98 Gene3D G3DSA:3.40.50.12740 5 98 1.4E-24 T 13-10-2018 MADE_1007975 b73fdb82f648c649b67c4dd4bfacfef1 98 SMART SM00448 6 97 2.2E-9 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007975 b73fdb82f648c649b67c4dd4bfacfef1 98 SUPERFAMILY SSF52172 6 97 3.7E-23 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 4 163 8.8E-78 T 13-10-2018 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 227 240 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 146 9.4E-47 T 13-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 3 356 49.856 T 13-10-2018 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 SUPERFAMILY SSF56784 3 159 2.67E-39 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 197 338 5.8E-63 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 168 356 36.184 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 SUPERFAMILY SSF54211 168 252 3.29E-31 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 Gene3D G3DSA:3.30.230.40 164 255 4.3E-36 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 150 1.2E-25 T 13-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 Gene3D G3DSA:3.30.230.40 256 356 2.6E-33 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 Gene3D G3DSA:3.40.50.1000 1 163 2.3E-46 T 13-10-2018 IPR023214 HAD superfamily MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 Pfam PF13242 HAD-hyrolase-like 104 147 2.7E-6 T 13-10-2018 MADE_1012310 e917cddc1243a33b08e63d4f0c47effd 356 SUPERFAMILY SSF54211 253 343 3.67E-28 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 333 352 1.5E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 122 134 1.5E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 239 252 1.5E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 98 116 1.5E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 539 552 1.5E-17 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 SUPERFAMILY SSF51419 67 346 1.57E-64 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PIRSF PIRSF001336 1 636 1.7E-248 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 Gene3D G3DSA:1.20.58.930 366 457 2.1E-222 T 13-10-2018 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 277 290 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MADE_1019500 4c61f9a54320220949662013c2cd079a 636 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 83 343 4.5E-44 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 TIGRFAM TIGR01273 speA: arginine decarboxylase 4 635 3.6E-217 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 98 116 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 323 340 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 539 560 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 486 511 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 90 104 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 66 81 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 146 161 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 196 218 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 172 193 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 PRINTS PR01180 Arginine decarboxylase signature 461 482 3.8E-62 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 Gene3D G3DSA:2.40.37.10 13 561 2.1E-222 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 SUPERFAMILY SSF50621 457 562 9.94E-8 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1019500 4c61f9a54320220949662013c2cd079a 636 Gene3D G3DSA:3.20.20.10 67 348 2.1E-222 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1009570 67a7bd7af324ae37b4062cc625291dac 564 SUPERFAMILY SSF51011 470 544 3.43E-7 T 13-10-2018 MADE_1009570 67a7bd7af324ae37b4062cc625291dac 564 Gene3D G3DSA:3.20.20.80 40 455 8.8E-89 T 13-10-2018 MADE_1009570 67a7bd7af324ae37b4062cc625291dac 564 SUPERFAMILY SSF51445 44 462 7.04E-73 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1009570 67a7bd7af324ae37b4062cc625291dac 564 SMART SM00642 51 453 1.1E-30 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009570 67a7bd7af324ae37b4062cc625291dac 564 Pfam PF00128 Alpha amylase, catalytic domain 95 416 1.2E-47 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009570 67a7bd7af324ae37b4062cc625291dac 564 Gene3D G3DSA:2.60.40.1180 457 542 2.2E-5 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1002270 3384878b26518a8d70f2a65252b5d94e 99 Pfam PF00276 Ribosomal protein L23 8 94 5.0E-33 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MADE_1002270 3384878b26518a8d70f2a65252b5d94e 99 SUPERFAMILY SSF54189 3 92 1.22E-32 T 13-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002270 3384878b26518a8d70f2a65252b5d94e 99 Gene3D G3DSA:3.30.70.330 1 99 1.6E-38 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MADE_1002270 3384878b26518a8d70f2a65252b5d94e 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 22.883 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 MADE_000001020810 cb4f1942f75cb1dc8224ca9a98b44864 424 SUPERFAMILY SSF81342 6 297 3.3E-88 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MADE_000001020810 cb4f1942f75cb1dc8224ca9a98b44864 424 SUPERFAMILY SSF81648 298 413 7.85E-33 T 13-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MADE_000001020810 cb4f1942f75cb1dc8224ca9a98b44864 424 PIRSF PIRSF038885 1 424 4.6E-151 T 13-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 MADE_000001020810 cb4f1942f75cb1dc8224ca9a98b44864 424 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 296 397 9.5E-40 T 13-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MADE_000001020810 cb4f1942f75cb1dc8224ca9a98b44864 424 Gene3D G3DSA:1.20.810.10 1 424 1.0E-144 T 13-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 MADE_000001020810 cb4f1942f75cb1dc8224ca9a98b44864 424 Pfam PF00033 Cytochrome b/b6/petB 24 211 5.7E-65 T 13-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 Pfam PF04055 Radical SAM superfamily 90 250 5.9E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 SMART SM00729 83 291 1.8E-13 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 Gene3D G3DSA:3.20.20.70 46 287 3.2E-21 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 SUPERFAMILY SSF102114 50 313 4.45E-67 T 13-10-2018 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 PIRSF PIRSF005963 1 320 1.3E-131 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 Hamap MF_00206 Lipoyl synthase [lipA]. 1 320 154.354 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 TIGRFAM TIGR00510 lipA: lipoyl synthase 22 319 4.1E-143 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MADE_000001021785 216d66134cf2d1fad4dac7a49a57037c 320 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 28 72 5.6E-9 T 13-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MADE_000001021100 275fecec6250080f3ba8d8b4b9919999 110 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 9 110 6.6E-35 T 13-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 MADE_000001021100 275fecec6250080f3ba8d8b4b9919999 110 Gene3D G3DSA:3.30.780.10 30 110 4.3E-31 T 13-10-2018 MADE_000001021100 275fecec6250080f3ba8d8b4b9919999 110 SUPERFAMILY SSF55159 9 106 5.1E-23 T 13-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 MADE_000001021100 275fecec6250080f3ba8d8b4b9919999 110 PIRSF PIRSF037511 1 110 3.5E-32 T 13-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 MADE_000001021100 275fecec6250080f3ba8d8b4b9919999 110 Pfam PF01253 Translation initiation factor SUI1 34 104 1.7E-17 T 13-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 MADE_1019230 828cd83211f8591f936107918e91baa5 641 SUPERFAMILY SSF55874 312 484 7.73E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019230 828cd83211f8591f936107918e91baa5 641 SMART SM00388 258 323 1.9E-23 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1019230 828cd83211f8591f936107918e91baa5 641 SMART SM00448 514 628 1.4E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1019230 828cd83211f8591f936107918e91baa5 641 Gene3D G3DSA:3.30.565.10 324 492 3.7E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019230 828cd83211f8591f936107918e91baa5 641 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 323 3.5E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1019230 828cd83211f8591f936107918e91baa5 641 Pfam PF00072 Response regulator receiver domain 516 627 4.9E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1019230 828cd83211f8591f936107918e91baa5 641 SUPERFAMILY SSF52172 513 631 8.25E-33 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1019230 828cd83211f8591f936107918e91baa5 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 486 5.1E-31 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1019230 828cd83211f8591f936107918e91baa5 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 8.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019230 828cd83211f8591f936107918e91baa5 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 428 8.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019230 828cd83211f8591f936107918e91baa5 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 442 8.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019230 828cd83211f8591f936107918e91baa5 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 8.6E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019230 828cd83211f8591f936107918e91baa5 641 Gene3D G3DSA:1.10.287.130 247 323 5.1E-24 T 13-10-2018 MADE_1019230 828cd83211f8591f936107918e91baa5 641 SMART SM00387 370 489 2.5E-37 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1019230 828cd83211f8591f936107918e91baa5 641 SUPERFAMILY SSF158472 200 248 1.23E-6 T 13-10-2018 MADE_1019230 828cd83211f8591f936107918e91baa5 641 SMART SM00304 198 250 6.2E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1019230 828cd83211f8591f936107918e91baa5 641 Gene3D G3DSA:3.40.50.2300 497 632 1.7E-35 T 13-10-2018 MADE_1019230 828cd83211f8591f936107918e91baa5 641 Gene3D G3DSA:1.10.8.500 199 246 1.2E-5 T 13-10-2018 MADE_1019230 828cd83211f8591f936107918e91baa5 641 SUPERFAMILY SSF47384 244 323 4.9E-21 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.1E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.1E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.1E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.1E-45 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 SUPERFAMILY SSF51735 8 254 1.15E-86 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 253 1.0E-68 T 13-10-2018 MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.6E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013725 a94c18979f5308d5234ed27dbf00508a 255 Gene3D G3DSA:3.40.50.720 1 254 1.6E-87 T 13-10-2018 MADE_1005705 50a9ed98747aa289804ae8c18bc98959 144 PIRSF PIRSF002889 1 142 1.4E-35 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MADE_1005705 50a9ed98747aa289804ae8c18bc98959 144 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 139 5.5E-33 T 13-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 MADE_1005705 50a9ed98747aa289804ae8c18bc98959 144 Pfam PF00460 Flagella basal body rod protein 13 39 5.5E-8 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 81 3.2E-21 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 Gene3D G3DSA:3.40.50.12780 50 515 1.9E-107 T 13-10-2018 MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 8.1E-302 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 SUPERFAMILY SSF56801 15 643 2.49E-185 T 13-10-2018 MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 13-10-2018 IPR020845 AMP-binding, conserved site MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 Pfam PF00501 AMP-binding enzyme 84 522 8.0E-92 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 51.671 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 2.4E-24 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MADE_000001023135 1585407b5dea8fa044aaa8129cd8f70d 648 Gene3D G3DSA:3.30.300.30 518 647 7.0E-32 T 13-10-2018 MADE_1002245 c2d9dba91797af18b7e360207a85269c 164 SMART SM00671 67 102 4.0E-4 T 13-10-2018 IPR006597 Sel1-like repeat MADE_1002245 c2d9dba91797af18b7e360207a85269c 164 SUPERFAMILY SSF81901 38 101 1.57E-11 T 13-10-2018 MADE_1002245 c2d9dba91797af18b7e360207a85269c 164 Gene3D G3DSA:1.25.40.10 28 133 1.7E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008090 326109db8848c4119461accc86f88d31 65 Pfam PF01632 Ribosomal protein L35 2 62 2.3E-24 T 13-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008090 326109db8848c4119461accc86f88d31 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.5E-20 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MADE_1008090 326109db8848c4119461accc86f88d31 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.5E-20 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MADE_1008090 326109db8848c4119461accc86f88d31 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.5E-20 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MADE_1008090 326109db8848c4119461accc86f88d31 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 1.7E-26 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MADE_1008090 326109db8848c4119461accc86f88d31 65 SUPERFAMILY SSF143034 2 64 3.27E-24 T 13-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008090 326109db8848c4119461accc86f88d31 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 13-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1008090 326109db8848c4119461accc86f88d31 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.675 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 MADE_1008090 326109db8848c4119461accc86f88d31 65 Gene3D G3DSA:2.40.50.530 1 64 2.0E-22 T 13-10-2018 MADE_1014410 94e74672ebeaa8e9dc9842c5bd5bd880 535 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 2 484 8.9E-93 T 13-10-2018 IPR013381 CRISPR-associated protein Cse1 MADE_1014410 94e74672ebeaa8e9dc9842c5bd5bd880 535 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 2 517 7.4E-127 T 13-10-2018 IPR013381 CRISPR-associated protein Cse1 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 190 3.9E-37 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 SUPERFAMILY SSF46609 1 84 1.1E-36 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 SUPERFAMILY SSF54719 84 192 1.7E-41 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.0E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.0E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 3.0E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 3.0E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 3.0E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 Gene3D G3DSA:2.40.500.20 83 193 1.3E-41 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 7.2E-35 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 Gene3D G3DSA:1.10.287.990 20 82 6.2E-27 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1006555 a5bf2ba22e4159377ed144a1fb82c0b1 193 PIRSF PIRSF000349 1 193 2.6E-84 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 Pfam PF00271 Helicase conserved C-terminal domain 242 351 3.7E-30 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 SMART SM00490 270 351 1.4E-32 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 Gene3D G3DSA:3.40.50.300 2 222 1.2E-69 T 13-10-2018 MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 7 389 50.749 T 13-10-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 SMART SM00487 27 234 4.7E-52 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 Pfam PF00270 DEAD/DEAH box helicase 32 207 3.5E-44 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 SUPERFAMILY SSF52540 83 363 1.29E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002850 214cac932c826d6cdc6cea85b7531d0f 429 Gene3D G3DSA:3.40.50.300 225 386 2.2E-48 T 13-10-2018 MADE_1015325 c88e189aa893a416aec03f57c90db41d 208 Gene3D G3DSA:3.40.1740.10 23 208 2.3E-69 T 13-10-2018 MADE_1015325 c88e189aa893a416aec03f57c90db41d 208 SUPERFAMILY SSF143456 25 208 4.58E-66 T 13-10-2018 MADE_1015325 c88e189aa893a416aec03f57c90db41d 208 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 25 208 38.114 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 MADE_1015325 c88e189aa893a416aec03f57c90db41d 208 Pfam PF02622 Uncharacterized ACR, COG1678 36 195 5.3E-52 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 Gene3D G3DSA:1.10.8.50 1 71 3.2E-25 T 13-10-2018 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.329 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 SUPERFAMILY SSF46946 2 114 7.46E-42 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.9E-30 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 PIRSF PIRSF002134 1 118 1.1E-38 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 Gene3D G3DSA:4.10.910.10 72 118 3.7E-25 T 13-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 13-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013950 c8747b9622fe216143539e12a63fd9ec 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 6.9E-51 T 13-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001021605 8d8b370fda6fe116a810056e34c5bc07 318 Pfam PF04198 Putative sugar-binding domain 62 316 5.0E-70 T 13-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 MADE_000001021605 8d8b370fda6fe116a810056e34c5bc07 318 Gene3D G3DSA:1.10.10.10 2 57 9.7E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001021605 8d8b370fda6fe116a810056e34c5bc07 318 SUPERFAMILY SSF100950 62 317 1.19E-64 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_000001021605 8d8b370fda6fe116a810056e34c5bc07 318 Gene3D G3DSA:3.40.50.1360 58 316 8.0E-66 T 13-10-2018 MADE_1007770 7dd01999d891cf4fffcd7e42f8df4624 108 Pfam PF01906 Putative heavy-metal-binding 1 104 2.0E-40 T 13-10-2018 IPR002765 Uncharacterised protein family UPF0145 MADE_1007770 7dd01999d891cf4fffcd7e42f8df4624 108 SUPERFAMILY SSF117782 1 105 2.75E-38 T 13-10-2018 IPR035439 UPF0145 domain superfamily MADE_1007770 7dd01999d891cf4fffcd7e42f8df4624 108 Gene3D G3DSA:3.30.110.70 2 106 7.7E-43 T 13-10-2018 MADE_1007770 7dd01999d891cf4fffcd7e42f8df4624 108 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 24.27 T 13-10-2018 IPR002765 Uncharacterised protein family UPF0145 MADE_1014255 373b8addb9c98fee2ac19b091a029d3a 504 SUPERFAMILY SSF56601 65 389 1.61E-57 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1014255 373b8addb9c98fee2ac19b091a029d3a 504 Gene3D G3DSA:3.40.710.10 61 404 3.1E-58 T 13-10-2018 MADE_1014255 373b8addb9c98fee2ac19b091a029d3a 504 Pfam PF00144 Beta-lactamase 66 389 2.6E-39 T 13-10-2018 IPR001466 Beta-lactamase-related MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:1.20.1640.10 507 1002 2.7E-241 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:3.30.2090.10 179 271 2.7E-241 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:3.30.70.1320 136 328 2.7E-241 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 SUPERFAMILY SSF82693 40 135 5.23E-20 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Pfam PF00873 AcrB/AcrD/AcrF family 3 1005 2.8E-157 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:3.30.70.1440 651 850 2.7E-241 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 SUPERFAMILY SSF82866 293 492 6.41E-34 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 SUPERFAMILY SSF82866 791 1008 3.14E-45 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 SUPERFAMILY SSF82714 708 784 1.26E-5 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 SUPERFAMILY SSF82714 184 266 2.49E-5 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:3.30.70.1430 552 650 2.7E-241 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:3.30.70.1430 40 800 2.7E-241 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:3.30.2090.10 702 792 2.7E-241 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 SUPERFAMILY SSF82693 136 325 5.23E-19 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 Gene3D G3DSA:1.20.1640.10 10 506 2.7E-241 T 13-10-2018 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 3.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 3.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 3.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021315 53cefb657af355c4b9499745b864b9c5 1013 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 Gene3D G3DSA:4.10.450.10 41 200 4.6E-181 T 13-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 Pfam PF05199 GMC oxidoreductase 391 529 1.6E-44 T 13-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 Gene3D G3DSA:1.10.1220.110 100 154 4.6E-181 T 13-10-2018 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 Gene3D G3DSA:3.30.410.40 155 474 4.6E-181 T 13-10-2018 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 SUPERFAMILY SSF54373 294 477 5.0E-54 T 13-10-2018 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 SUPERFAMILY SSF51905 7 537 1.02E-86 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1012115 1b1025015283475562eea7f3c68bd666 550 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 85 108 - T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 258 272 - T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 Pfam PF00732 GMC oxidoreductase 8 299 3.9E-90 T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 PIRSF PIRSF000137 2 544 2.3E-155 T 13-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_1012115 1b1025015283475562eea7f3c68bd666 550 Gene3D G3DSA:3.50.50.60 8 533 4.6E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1013195 c89842e3df4472275182f1fe12844bd1 363 Pfam PF00534 Glycosyl transferases group 1 161 327 4.3E-16 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1013195 c89842e3df4472275182f1fe12844bd1 363 Gene3D G3DSA:3.40.50.2000 82 344 5.6E-29 T 13-10-2018 MADE_1013195 c89842e3df4472275182f1fe12844bd1 363 Gene3D G3DSA:3.40.50.2000 150 337 5.6E-29 T 13-10-2018 MADE_1013195 c89842e3df4472275182f1fe12844bd1 363 SUPERFAMILY SSF53756 22 347 1.31E-38 T 13-10-2018 MADE_1012025 3beb2d5d2a1239036a4bb6ed867f71da 355 Gene3D G3DSA:3.30.1380.10 224 311 1.5E-12 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MADE_1012025 3beb2d5d2a1239036a4bb6ed867f71da 355 SUPERFAMILY SSF55166 205 352 1.92E-17 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MADE_1012025 3beb2d5d2a1239036a4bb6ed867f71da 355 Pfam PF08291 Peptidase M15 204 290 2.7E-11 T 13-10-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 MADE_1001540 1149b51d420d0d4c20ce3908fd96d505 169 Pfam PF04214 Protein of unknown function, DUF 69 136 1.6E-24 T 13-10-2018 IPR007332 Protein of unknown function DUF411 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 Gene3D G3DSA:1.10.287.130 136 189 1.0E-14 T 13-10-2018 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 SUPERFAMILY SSF55874 199 352 1.44E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 236 352 7.0E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 Gene3D G3DSA:3.30.450.20 4 115 1.8E-20 T 13-10-2018 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 SMART SM00091 6 74 4.4E-6 T 13-10-2018 IPR000014 PAS domain MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 Pfam PF00512 His Kinase A (phospho-acceptor) domain 134 189 1.0E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 315 333 8.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 300 8.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 351 8.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 SMART SM00388 132 196 5.0E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 Gene3D G3DSA:3.30.565.10 195 353 2.8E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 SUPERFAMILY SSF47384 132 188 4.32E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 Pfam PF00989 PAS fold 8 106 1.3E-9 T 13-10-2018 IPR013767 PAS fold GO:0006355 MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 SMART SM00387 235 354 8.2E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015995 0afe1b07721ad5e5e0e14673f5167887 361 SUPERFAMILY SSF55785 9 107 8.72E-12 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 Gene3D G3DSA:3.50.50.60 248 399 9.9E-43 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 SUPERFAMILY SSF51971 145 400 1.12E-65 T 13-10-2018 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 134 2.0E-37 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 SUPERFAMILY SSF46548 6 157 3.87E-41 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 Gene3D G3DSA:3.50.50.60 147 242 9.2E-10 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 Gene3D G3DSA:1.10.1060.10 12 146 6.3E-34 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 6 471 1.1E-244 T 13-10-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 458 2.9E-22 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 1.9E-34 T 13-10-2018 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 PRINTS PR00419 Adrenodoxin reductase family signature 289 303 1.9E-34 T 13-10-2018 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 PRINTS PR00419 Adrenodoxin reductase family signature 323 336 1.9E-34 T 13-10-2018 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 1.9E-34 T 13-10-2018 MADE_1015790 a5ff6853fb748a82cfd81611bbafcfff 471 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 1.9E-34 T 13-10-2018 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 Gene3D G3DSA:3.90.1170.20 8 280 2.8E-113 T 13-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 13 281 5.8E-94 T 13-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 Gene3D G3DSA:3.20.20.70 125 271 2.8E-113 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 PIRSF PIRSF006250 4 284 8.5E-99 T 13-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 SUPERFAMILY SSF51690 117 281 7.46E-59 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 29 114 5.7E-26 T 13-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 SUPERFAMILY SSF54675 6 114 1.73E-29 T 13-10-2018 MADE_1015005 be3b8b5bbca7b5ed1358a242c69f320b 284 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 117 280 4.5E-58 T 13-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 288 5.8E-34 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 Gene3D G3DSA:3.40.50.720 1 169 3.0E-48 T 13-10-2018 MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 PIRSF PIRSF000103 1 291 1.0E-65 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 SUPERFAMILY SSF51735 4 167 8.44E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 164 8.0E-48 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 13-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 SUPERFAMILY SSF48179 169 290 4.42E-39 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1009635 d5f1f677dd612129751e74583ba441fe 291 Gene3D G3DSA:1.10.1040.10 170 291 2.5E-37 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 Pfam PF13377 Periplasmic binding protein-like domain 169 329 4.2E-27 T 13-10-2018 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 SMART SM00354 1 71 2.2E-31 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 8.0E-7 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 8.0E-7 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.9E-21 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 13-10-2018 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 Gene3D G3DSA:3.40.50.2300 160 289 4.0E-64 T 13-10-2018 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 Gene3D G3DSA:3.40.50.2300 63 305 4.0E-64 T 13-10-2018 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 SUPERFAMILY SSF47413 1 59 1.29E-19 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 SUPERFAMILY SSF53822 61 330 1.41E-68 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1001125 60a3c3066099cc8916fbd895423378ab 333 Gene3D G3DSA:1.10.260.40 1 60 4.7E-25 T 13-10-2018 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 SMART SM00382 150 294 1.2E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 Gene3D G3DSA:1.10.10.60 413 484 8.4E-14 T 13-10-2018 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 Gene3D G3DSA:3.40.50.2300 1 118 6.8E-7 T 13-10-2018 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 Pfam PF00158 Sigma-54 interaction domain 130 296 2.9E-73 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 SUPERFAMILY SSF46689 342 481 2.51E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 Pfam PF02954 Bacterial regulatory protein, Fis family 439 479 9.7E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 Gene3D G3DSA:1.10.8.60 302 377 4.7E-22 T 13-10-2018 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 154 167 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 SUPERFAMILY SSF52172 1 174 1.54E-8 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216 231 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 SUPERFAMILY SSF52540 130 372 1.86E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 462 482 2.7E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 445 462 2.7E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 Gene3D G3DSA:3.40.50.300 119 301 2.0E-66 T 13-10-2018 MADE_1005880 e83bae02c57d2a788dfb4f0c1a16d6d7 487 Pfam PF06490 Flagellar regulatory protein FleQ 4 108 6.8E-24 T 13-10-2018 IPR010518 Flagellar regulatory FleQ MADE_1008665 be0ba0243df820489dcc69dd1889befc 234 SUPERFAMILY SSF56784 15 233 4.67E-56 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1008665 be0ba0243df820489dcc69dd1889befc 234 Gene3D G3DSA:1.10.150.240 38 104 1.9E-52 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MADE_1008665 be0ba0243df820489dcc69dd1889befc 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 26 204 1.6E-34 T 13-10-2018 MADE_1008665 be0ba0243df820489dcc69dd1889befc 234 Gene3D G3DSA:3.40.50.1000 26 225 1.9E-52 T 13-10-2018 IPR023214 HAD superfamily MADE_1008665 be0ba0243df820489dcc69dd1889befc 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 147 198 2.7E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1008665 be0ba0243df820489dcc69dd1889befc 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 110 204 9.7E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1015055 237e4d569b04780a93e6c6659f8c639f 122 SUPERFAMILY SSF52172 4 119 6.4E-34 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015055 237e4d569b04780a93e6c6659f8c639f 122 Gene3D G3DSA:3.40.50.12740 3 122 4.9E-34 T 13-10-2018 MADE_1015055 237e4d569b04780a93e6c6659f8c639f 122 Pfam PF00072 Response regulator receiver domain 4 115 5.4E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015055 237e4d569b04780a93e6c6659f8c639f 122 SMART SM00448 2 115 2.2E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001023235 2320fe7ec87f52f9a5981d426c5ac3b2 296 Gene3D G3DSA:3.40.190.290 95 294 2.3E-11 T 13-10-2018 MADE_000001023235 2320fe7ec87f52f9a5981d426c5ac3b2 296 Pfam PF03466 LysR substrate binding domain 95 292 2.9E-9 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_000001023235 2320fe7ec87f52f9a5981d426c5ac3b2 296 Gene3D G3DSA:1.10.10.10 3 94 7.0E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001023235 2320fe7ec87f52f9a5981d426c5ac3b2 296 SUPERFAMILY SSF46785 2 85 2.36E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001023235 2320fe7ec87f52f9a5981d426c5ac3b2 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 8.1E-15 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_000001023235 2320fe7ec87f52f9a5981d426c5ac3b2 296 SUPERFAMILY SSF53850 94 293 6.69E-20 T 13-10-2018 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 Gene3D G3DSA:1.10.520.10 47 451 3.7E-197 T 13-10-2018 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 ProSitePatterns PS00436 Peroxidases active site signature. 114 125 - T 13-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 Gene3D G3DSA:1.10.420.20 214 418 3.7E-197 T 13-10-2018 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 37 757 0.0 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 Gene3D G3DSA:1.10.520.10 454 756 1.1E-134 T 13-10-2018 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 Gene3D G3DSA:1.10.420.10 609 732 1.1E-134 T 13-10-2018 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 SUPERFAMILY SSF48113 451 756 4.13E-101 T 13-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 Hamap MF_01961 Catalase-peroxidase [katG]. 27 757 39.675 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 277 287 - T 13-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 SUPERFAMILY SSF48113 46 450 3.54E-140 T 13-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00458 Haem peroxidase superfamily signature 174 191 1.2E-14 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00458 Haem peroxidase superfamily signature 337 352 1.2E-14 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00458 Haem peroxidase superfamily signature 192 204 1.2E-14 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00458 Haem peroxidase superfamily signature 277 292 1.2E-14 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00458 Haem peroxidase superfamily signature 114 128 1.2E-14 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 Pfam PF00141 Peroxidase 424 730 6.0E-34 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 Pfam PF00141 Peroxidase 108 416 4.2E-48 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 285 308 1.6E-40 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 501 527 1.6E-40 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 76 89 1.6E-40 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 91 116 1.6E-40 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 MADE_1016605 67b5ebb995703dfc8d319720b896d9b0 766 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 50 72 1.6E-40 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 MADE_1009345 5ea252e92bfc9f2fecfadbf2de815c3d 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 78 118 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MADE_1009345 5ea252e92bfc9f2fecfadbf2de815c3d 157 Gene3D G3DSA:3.40.140.10 18 157 4.1E-48 T 13-10-2018 MADE_1009345 5ea252e92bfc9f2fecfadbf2de815c3d 157 SUPERFAMILY SSF53927 28 155 1.02E-41 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MADE_1009345 5ea252e92bfc9f2fecfadbf2de815c3d 157 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 30 154 7.3E-43 T 13-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 MADE_1009345 5ea252e92bfc9f2fecfadbf2de815c3d 157 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 27 126 1.2E-14 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MADE_1013535 f323f262e65159df919928101e7d3922 168 Pfam PF00994 Probable molybdopterin binding domain 11 152 1.2E-33 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1013535 f323f262e65159df919928101e7d3922 168 SUPERFAMILY SSF53218 4 164 7.46E-46 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily MADE_1013535 f323f262e65159df919928101e7d3922 168 PIRSF PIRSF006443 1 163 1.0E-63 T 13-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 MADE_1013535 f323f262e65159df919928101e7d3922 168 Gene3D G3DSA:3.40.980.10 2 168 4.1E-50 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily MADE_1013535 f323f262e65159df919928101e7d3922 168 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 6 165 4.0E-82 T 13-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 MADE_1013535 f323f262e65159df919928101e7d3922 168 SMART SM00852 11 155 1.1E-28 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1013535 f323f262e65159df919928101e7d3922 168 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 9 148 3.4E-35 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1016630 636855959312e3fd7e2747143ef0e93a 864 Pfam PF00593 TonB dependent receptor 361 857 1.6E-34 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1016630 636855959312e3fd7e2747143ef0e93a 864 Gene3D G3DSA:2.170.130.10 37 178 1.3E-28 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1016630 636855959312e3fd7e2747143ef0e93a 864 SUPERFAMILY SSF56935 40 858 1.43E-96 T 13-10-2018 MADE_1016630 636855959312e3fd7e2747143ef0e93a 864 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 174 2.5E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1004565 d9e12a0103635d8f7e7cf799eef5b95b 378 Gene3D G3DSA:2.30.30.60 193 243 3.9E-11 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1004565 d9e12a0103635d8f7e7cf799eef5b95b 378 Gene3D G3DSA:3.30.70.100 247 343 1.3E-18 T 13-10-2018 MADE_1004565 d9e12a0103635d8f7e7cf799eef5b95b 378 Pfam PF00924 Mechanosensitive ion channel 136 339 2.8E-46 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1004565 d9e12a0103635d8f7e7cf799eef5b95b 378 SUPERFAMILY SSF50182 178 243 2.84E-16 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1004565 d9e12a0103635d8f7e7cf799eef5b95b 378 SUPERFAMILY SSF82861 97 176 1.31E-11 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MADE_1004565 d9e12a0103635d8f7e7cf799eef5b95b 378 SUPERFAMILY SSF82689 252 349 6.41E-20 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1008745 b7903623b8d743260c7ee36d555e055c 210 SUPERFAMILY SSF51735 2 200 5.32E-40 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008745 b7903623b8d743260c7ee36d555e055c 210 Gene3D G3DSA:3.40.50.720 1 210 1.2E-50 T 13-10-2018 MADE_1008745 b7903623b8d743260c7ee36d555e055c 210 Pfam PF13460 NAD(P)H-binding 8 188 9.7E-41 T 13-10-2018 IPR016040 NAD(P)-binding domain MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 452 4.7E-18 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Gene3D G3DSA:1.10.540.10 14 158 1.5E-7 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Gene3D G3DSA:1.20.140.10 290 457 3.9E-40 T 13-10-2018 MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 157 7.7E-5 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 SUPERFAMILY SSF47203 288 468 4.67E-39 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 SUPERFAMILY SSF56645 36 294 1.23E-46 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 1.4E-8 T 13-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 469 593 5.0E-25 T 13-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Gene3D G3DSA:2.40.110.10 160 289 1.9E-25 T 13-10-2018 MADE_1013730 72832ccfa05c0a30f96509f5a9d00216 600 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 270 7.9E-16 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 Pfam PF12697 Alpha/beta hydrolase family 21 254 4.3E-23 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 Gene3D G3DSA:3.40.50.1820 9 262 4.5E-66 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 10 261 40.22 T 13-10-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 17 259 7.4E-78 T 13-10-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 6.4E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 6.4E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 6.4E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 6.4E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1020010 99170a9c0ae38e7ca99d9ced6f190051 269 SUPERFAMILY SSF53474 8 261 5.4E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 50 68 - T 13-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 255 1.3E-85 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 258 469 30.929 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 Gene3D G3DSA:3.20.20.70 259 463 5.1E-164 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 SUPERFAMILY SSF51366 1 256 2.26E-76 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 257 33.318 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 Gene3D G3DSA:3.20.20.70 8 258 5.1E-164 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 SUPERFAMILY SSF51366 260 467 9.42E-52 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MADE_1006885 f7e3c72be2739814487c5a7da10bf634 469 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 260 463 2.2E-50 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 216 7.2E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 Gene3D G3DSA:1.10.10.10 122 220 2.5E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 SUPERFAMILY SSF52172 1 118 8.68E-37 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 Pfam PF00072 Response regulator receiver domain 3 112 8.7E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 SUPERFAMILY SSF46894 121 216 1.13E-25 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 SMART SM00862 145 216 6.5E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 SMART SM00448 1 112 2.9E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004130 1c61997f9539e9aef424be4c1521b203 221 Gene3D G3DSA:3.40.50.2300 1 121 7.3E-38 T 13-10-2018 MADE_1018325 24f8bcbb64b8f10c070cdcf712bc40bc 295 Pfam PF02219 Methylenetetrahydrofolate reductase 19 290 1.5E-96 T 13-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 MADE_1018325 24f8bcbb64b8f10c070cdcf712bc40bc 295 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 23 289 1.8E-99 T 13-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 MADE_1018325 24f8bcbb64b8f10c070cdcf712bc40bc 295 SUPERFAMILY SSF51730 21 292 1.31E-92 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like MADE_1018325 24f8bcbb64b8f10c070cdcf712bc40bc 295 Gene3D G3DSA:3.20.20.220 2 295 1.1E-106 T 13-10-2018 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Gene3D G3DSA:3.40.50.12740 591 710 5.9E-38 T 13-10-2018 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Pfam PF00072 Response regulator receiver domain 594 704 8.2E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Pfam PF00072 Response regulator receiver domain 461 540 3.5E-10 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 29 124 2.3E-13 T 13-10-2018 IPR029095 NarX-like, N-terminal MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 440 3.3E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 281 2.1E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Gene3D G3DSA:1.10.287.130 184 279 9.7E-23 T 13-10-2018 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SUPERFAMILY SSF52172 456 576 1.07E-12 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SMART SM00448 592 704 1.8E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SMART SM00448 457 571 0.0019 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SMART SM00388 218 281 6.6E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SUPERFAMILY SSF52172 590 709 6.83E-36 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Gene3D G3DSA:3.40.50.2300 451 584 2.3E-14 T 13-10-2018 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 440 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 396 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 4.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SMART SM00387 328 443 2.6E-34 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SUPERFAMILY SSF55874 270 439 6.55E-46 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 Gene3D G3DSA:3.30.565.10 280 444 2.3E-51 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1011780 39d85b85a93d947ff076fe5cbbd43627 710 SUPERFAMILY SSF47384 204 282 1.73E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Pfam PF00873 AcrB/AcrD/AcrF family 5 1030 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 SUPERFAMILY SSF82693 155 333 3.92E-18 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:1.20.1640.10 518 1027 2.8E-282 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:3.30.70.1430 568 669 2.8E-282 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 SUPERFAMILY SSF82693 42 127 8.2E-21 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:3.30.2090.10 724 812 2.8E-282 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 SUPERFAMILY SSF82866 813 1034 1.22E-51 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 3.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 3.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 3.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 3.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.6E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1035 0.0 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:3.30.70.1430 42 820 2.8E-282 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 SUPERFAMILY SSF82714 192 275 1.31E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:3.30.70.1440 670 870 2.8E-282 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 SUPERFAMILY SSF82866 299 508 5.75E-36 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:3.30.2090.10 188 278 2.8E-282 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 SUPERFAMILY SSF82693 568 667 6.28E-6 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 SUPERFAMILY SSF82714 725 807 3.27E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:3.30.70.1320 136 335 2.8E-282 T 13-10-2018 MADE_1010275 f9d4f1f9177f2370cf735619dcc7b5d0 1044 Gene3D G3DSA:1.20.1640.10 15 517 2.8E-282 T 13-10-2018 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 Gene3D G3DSA:3.40.228.10 138 336 4.6E-97 T 13-10-2018 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 Pfam PF00384 Molybdopterin oxidoreductase 63 483 6.3E-42 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 SMART SM00926 6 60 2.1E-14 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 10 54 3.4E-11 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 SUPERFAMILY SSF50692 597 728 3.16E-33 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 SUPERFAMILY SSF53706 8 486 1.1E-121 T 13-10-2018 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 Gene3D G3DSA:3.40.50.740 70 485 4.6E-97 T 13-10-2018 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 Gene3D G3DSA:2.40.40.20 589 729 8.8E-31 T 13-10-2018 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 Pfam PF01568 Molydopterin dinucleotide binding domain 602 721 1.6E-22 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MADE_1018195 a3ebdebeeba67d2b157ee66305c3c49c 729 Gene3D G3DSA:2.20.25.90 1 65 3.2E-16 T 13-10-2018 MADE_1004855 160b6f3626cfda1a54fc1c9be4c2db97 295 SUPERFAMILY SSF53448 21 294 8.1E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1004855 160b6f3626cfda1a54fc1c9be4c2db97 295 Gene3D G3DSA:3.90.550.10 3 262 2.7E-29 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1004855 160b6f3626cfda1a54fc1c9be4c2db97 295 Pfam PF00535 Glycosyl transferase family 2 21 156 5.6E-13 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 Gene3D G3DSA:3.40.50.720 309 503 1.2E-63 T 13-10-2018 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 Gene3D G3DSA:1.10.1040.50 504 707 2.6E-71 T 13-10-2018 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 319 498 2.0E-57 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 TIGRFAM TIGR02440 FadJ: fatty oxidation complex, alpha subunit FadJ 11 712 0.0 T 13-10-2018 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 624 708 4.7E-5 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 501 594 2.8E-24 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 SUPERFAMILY SSF51735 316 498 1.28E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 SUPERFAMILY SSF48179 501 600 2.21E-27 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 13-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 SUPERFAMILY SSF52096 10 308 3.25E-68 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 498 523 - T 13-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 SUPERFAMILY SSF48179 619 712 3.49E-26 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 Gene3D G3DSA:3.90.226.10 8 308 1.2E-99 T 13-10-2018 MADE_000001020935 686e1316de45c763d8eeaf3ef9a4238f 713 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 225 5.4E-44 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MADE_1000355 e8bf7388d18c6352eccdebe59fdc570c 101 SUPERFAMILY SSF47413 43 100 7.1E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1000355 e8bf7388d18c6352eccdebe59fdc570c 101 Pfam PF01381 Helix-turn-helix 46 90 5.2E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1000355 e8bf7388d18c6352eccdebe59fdc570c 101 SMART SM00530 45 100 1.2E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1000355 e8bf7388d18c6352eccdebe59fdc570c 101 Gene3D G3DSA:1.10.260.40 2 99 9.9E-17 T 13-10-2018 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 SUPERFAMILY SSF52418 73 332 8.11E-88 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 Gene3D G3DSA:1.20.970.10 14 186 1.5E-119 T 13-10-2018 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 8 334 1.2E-120 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 Gene3D G3DSA:3.40.1030.10 70 323 1.5E-119 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 Pfam PF00591 Glycosyl transferase family, a/b domain 76 323 2.1E-95 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 66 3.7E-15 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 6 335 37.853 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 MADE_1006890 040c090cd7f1870395d95020ea14e046 343 SUPERFAMILY SSF47648 6 70 4.45E-17 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1019530 0febf270e94374878dd9e2253ec5b8ba 522 Pfam PF04820 Tryptophan halogenase 10 473 3.1E-121 T 13-10-2018 IPR006905 Flavin-dependent halogenase MADE_1019530 0febf270e94374878dd9e2253ec5b8ba 522 PIRSF PIRSF011396 2 519 1.0E-167 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase MADE_1019530 0febf270e94374878dd9e2253ec5b8ba 522 Gene3D G3DSA:3.50.50.60 3 518 8.0E-185 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1019530 0febf270e94374878dd9e2253ec5b8ba 522 SUPERFAMILY SSF51905 5 443 1.87E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009940 799800c521b375ed2343e80cd98e1f98 260 PIRSF PIRSF020736 4 259 7.4E-88 T 13-10-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 MADE_1009940 799800c521b375ed2343e80cd98e1f98 260 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 12 254 8.9E-103 T 13-10-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 MADE_1009940 799800c521b375ed2343e80cd98e1f98 260 Gene3D G3DSA:1.20.1260.10 107 260 1.3E-51 T 13-10-2018 IPR012347 Ferritin-like MADE_1009940 799800c521b375ed2343e80cd98e1f98 260 Gene3D G3DSA:1.20.1260.10 9 75 2.0E-16 T 13-10-2018 IPR012347 Ferritin-like MADE_1009940 799800c521b375ed2343e80cd98e1f98 260 SUPERFAMILY SSF47240 13 257 5.41E-70 T 13-10-2018 IPR009078 Ferritin-like superfamily MADE_1018350 1294f7dfee7003b1a0d4666734897ae0 145 SUPERFAMILY SSF69500 4 144 3.4E-54 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MADE_1018350 1294f7dfee7003b1a0d4666734897ae0 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 145 7.9E-62 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MADE_1018350 1294f7dfee7003b1a0d4666734897ae0 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 4 143 5.6E-54 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MADE_1018350 1294f7dfee7003b1a0d4666734897ae0 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.408 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 MADE_1018350 1294f7dfee7003b1a0d4666734897ae0 145 Gene3D G3DSA:3.50.80.10 1 145 5.2E-56 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily MADE_1009270 14a381e4c2e43403c294e1a25b183271 105 ProDom PD012578 PLASMID TOXIN CCDB CYTOTOXIC LETB POST-SEGREGATION SYSTEM CCDB-LIKE GYRASE FUSED-CCDB 18 104 2.0E-12 T 13-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 MADE_1009270 14a381e4c2e43403c294e1a25b183271 105 SUPERFAMILY SSF50118 2 105 2.94E-30 T 13-10-2018 MADE_1009270 14a381e4c2e43403c294e1a25b183271 105 Gene3D G3DSA:2.30.30.110 1 105 6.5E-34 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MADE_1009270 14a381e4c2e43403c294e1a25b183271 105 Pfam PF01845 CcdB protein 3 104 7.8E-32 T 13-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 5.0E-42 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 PIRSF PIRSF002133 1 124 7.9E-54 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 SUPERFAMILY SSF50249 3 123 1.63E-50 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 2.7E-69 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 Gene3D G3DSA:2.40.50.140 1 124 2.1E-62 T 13-10-2018 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.9E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.9E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.9E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.9E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.9E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.9E-60 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001023290 3d27b2ecb5ea02ba6eaa1b4933358519 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.02 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1011610 aaaf7f46703ff56cf819a07b6a1d58c7 968 Pfam PF03993 Domain of Unknown Function (DUF349) 690 734 7.3E-8 T 13-10-2018 IPR007139 Protein of unknown function DUF349 MADE_1011610 aaaf7f46703ff56cf819a07b6a1d58c7 968 Pfam PF03993 Domain of Unknown Function (DUF349) 593 666 3.4E-12 T 13-10-2018 IPR007139 Protein of unknown function DUF349 MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 271 29.455 T 13-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 SUPERFAMILY SSF53223 1 102 2.07E-25 T 13-10-2018 MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 Gene3D G3DSA:3.40.50.720 103 246 1.2E-74 T 13-10-2018 MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 270 1.4E-71 T 13-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 89 4.9E-20 T 13-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 117 192 5.3E-13 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 SUPERFAMILY SSF51735 103 271 9.31E-38 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1000150 30d81f9a2cdfa7cf22a1911bbd2a9e46 279 Gene3D G3DSA:3.40.50.10860 5 255 1.2E-74 T 13-10-2018 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 44 7.0E-9 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.396 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 Pfam PF01165 Ribosomal protein S21 4 56 1.3E-22 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 Gene3D G3DSA:1.20.5.1150 16 54 1.3E-20 T 13-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 1.3E-24 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 13-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.1E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.1E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.1E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003780 7594f1b6b9d5bf7b83ac250d1277ab57 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.1E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1001015 390c4c37f074d09438ed049583870e17 416 Gene3D G3DSA:2.40.37.10 16 409 3.4E-146 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 SUPERFAMILY SSF51419 26 283 2.91E-80 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1001015 390c4c37f074d09438ed049583870e17 416 SUPERFAMILY SSF50621 256 413 2.51E-52 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 282 370 4.5E-25 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 281 3.0E-74 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 6.5E-28 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 380 402 6.5E-28 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 6.5E-28 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 299 317 6.5E-28 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1001015 390c4c37f074d09438ed049583870e17 416 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 57 75 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site MADE_1001015 390c4c37f074d09438ed049583870e17 416 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 225 241 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site MADE_1001015 390c4c37f074d09438ed049583870e17 416 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 413 40.858 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1001015 390c4c37f074d09438ed049583870e17 416 Gene3D G3DSA:3.20.20.10 34 276 3.4E-146 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1001015 390c4c37f074d09438ed049583870e17 416 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 412 1.2E-159 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 370 383 2.8E-27 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 271 290 2.8E-27 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 2.8E-27 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 2.8E-27 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1001015 390c4c37f074d09438ed049583870e17 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 2.8E-27 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 SUPERFAMILY SSF53067 503 746 4.05E-6 T 13-10-2018 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Gene3D G3DSA:3.30.110.120 268 393 3.8E-125 T 13-10-2018 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Pfam PF01300 Telomere recombination 225 406 3.1E-40 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Gene3D G3DSA:3.90.870.50 21 384 3.8E-125 T 13-10-2018 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Gene3D G3DSA:3.30.420.350 505 749 1.4E-100 T 13-10-2018 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Gene3D G3DSA:3.30.420.360 407 760 1.4E-100 T 13-10-2018 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Pfam PF00708 Acylphosphatase 19 101 1.2E-13 T 13-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 SUPERFAMILY SSF54975 15 102 1.13E-16 T 13-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Pfam PF07503 HypF finger 171 201 2.6E-13 T 13-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 Pfam PF07503 HypF finger 121 153 2.5E-10 T 13-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 PIRSF PIRSF006256 14 768 3.6E-226 T 13-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 SUPERFAMILY SSF55821 188 411 4.27E-38 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MADE_1001705 ca662fcf9b74245c62a3deadd05e0b86 768 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 22 761 7.9E-194 T 13-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 MADE_1000445 13020b5ce29465b3b1847791f88e8903 554 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1000445 13020b5ce29465b3b1847791f88e8903 554 SUPERFAMILY SSF52540 348 535 5.78E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000445 13020b5ce29465b3b1847791f88e8903 554 SMART SM00382 361 548 5.2E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1000445 13020b5ce29465b3b1847791f88e8903 554 Pfam PF00005 ABC transporter 352 503 7.4E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1000445 13020b5ce29465b3b1847791f88e8903 554 Gene3D G3DSA:3.40.50.300 328 542 1.3E-44 T 13-10-2018 MADE_1000445 13020b5ce29465b3b1847791f88e8903 554 Gene3D G3DSA:1.20.1560.10 4 323 3.5E-14 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1000445 13020b5ce29465b3b1847791f88e8903 554 SUPERFAMILY SSF90123 9 319 6.67E-26 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1018270 3a303712e2a137b049bbe00220e8ecb4 333 Pfam PF08443 RimK-like ATP-grasp domain 169 329 3.1E-8 T 13-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 MADE_1018270 3a303712e2a137b049bbe00220e8ecb4 333 Gene3D G3DSA:3.30.470.20 231 333 1.1E-14 T 13-10-2018 MADE_1018270 3a303712e2a137b049bbe00220e8ecb4 333 SUPERFAMILY SSF56059 145 315 7.3E-16 T 13-10-2018 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 527 52.035 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 Pfam PF00009 Elongation factor Tu GTP binding domain 12 277 8.6E-46 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 SUPERFAMILY SSF52540 9 277 1.5E-84 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 PRINTS PR00315 GTP-binding elongation factor signature 65 73 3.3E-10 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.3E-10 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 PRINTS PR00315 GTP-binding elongation factor signature 85 95 3.3E-10 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 PRINTS PR00315 GTP-binding elongation factor signature 137 146 3.3E-10 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 Gene3D G3DSA:3.30.70.3280 390 529 6.0E-51 T 13-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 528 4.2E-298 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 Pfam PF03144 Elongation factor Tu domain 2 314 380 7.6E-11 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 Gene3D G3DSA:3.40.50.300 72 379 3.2E-114 T 13-10-2018 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 SUPERFAMILY SSF50447 262 393 6.13E-30 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 Gene3D G3DSA:3.40.50.300 110 275 3.2E-114 T 13-10-2018 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 SUPERFAMILY SSF54980 393 468 2.48E-16 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 174 2.5E-18 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1006380 f33463f72f9374bf1aae24611e67a19c 529 Pfam PF16658 Class II release factor RF3, C-terminal domain 387 514 2.3E-45 T 13-10-2018 IPR032090 Peptide chain release factor 3, C-terminal MADE_1005580 28b37eab05804bd3c47df4ba32d512a8 336 SUPERFAMILY SSF56349 122 315 3.24E-36 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1005580 28b37eab05804bd3c47df4ba32d512a8 336 Gene3D G3DSA:1.10.443.10 124 313 4.8E-39 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1005580 28b37eab05804bd3c47df4ba32d512a8 336 Pfam PF00589 Phage integrase family 135 311 7.8E-15 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1005580 28b37eab05804bd3c47df4ba32d512a8 336 SUPERFAMILY SSF47823 31 123 5.49E-27 T 13-10-2018 MADE_1005580 28b37eab05804bd3c47df4ba32d512a8 336 Gene3D G3DSA:1.10.150.130 25 121 1.1E-19 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 SMART SM00028 451 484 23.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 SMART SM00028 231 264 0.16 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 SMART SM00028 197 230 3.8 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 SUPERFAMILY SSF48452 173 482 1.65E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 Pfam PF13432 Tetratricopeptide repeat 202 263 3.6E-6 T 13-10-2018 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 Pfam PF00072 Response regulator receiver domain 8 123 7.8E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 Gene3D G3DSA:3.40.50.2300 1 125 5.5E-20 T 13-10-2018 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 SUPERFAMILY SSF52172 4 142 7.68E-25 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 SMART SM00448 6 123 3.8E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1009805 0b5211b630dcaa44b9e908d60360e770 546 Gene3D G3DSA:1.25.40.10 126 279 5.1E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1009785 6bd6bd559d038c1613e2a16124321e56 503 SUPERFAMILY SSF46689 15 114 5.2E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1009785 6bd6bd559d038c1613e2a16124321e56 503 SUPERFAMILY SSF53098 132 262 6.83E-18 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1009785 6bd6bd559d038c1613e2a16124321e56 503 Pfam PF00665 Integrase core domain 137 252 1.6E-10 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1009785 6bd6bd559d038c1613e2a16124321e56 503 SUPERFAMILY SSF46689 375 487 2.87E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1009785 6bd6bd559d038c1613e2a16124321e56 503 Pfam PF13551 Winged helix-turn helix 388 445 8.5E-8 T 13-10-2018 MADE_1009785 6bd6bd559d038c1613e2a16124321e56 503 Gene3D G3DSA:3.30.420.10 127 270 8.2E-10 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 PRINTS PR01374 Gram-negative bacterial tonB protein signature 138 156 7.2E-13 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 PRINTS PR01374 Gram-negative bacterial tonB protein signature 117 138 7.2E-13 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 PRINTS PR01374 Gram-negative bacterial tonB protein signature 157 174 7.2E-13 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 PRINTS PR01374 Gram-negative bacterial tonB protein signature 59 69 7.2E-13 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 122 199 5.1E-19 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 Gene3D G3DSA:3.30.1150.10 107 201 1.5E-23 T 13-10-2018 MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 123 198 3.1E-15 T 13-10-2018 IPR006260 TonB/TolA, C-terminal MADE_1003895 41a2812941394fd9fa95be19b5fa0b4c 202 SUPERFAMILY SSF74653 113 194 1.24E-24 T 13-10-2018 MADE_1015490 11f4f95ea664dd0eb328269c826310dd 292 Gene3D G3DSA:3.40.190.290 92 289 1.6E-61 T 13-10-2018 MADE_1015490 11f4f95ea664dd0eb328269c826310dd 292 SUPERFAMILY SSF53850 89 288 7.02E-43 T 13-10-2018 MADE_1015490 11f4f95ea664dd0eb328269c826310dd 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 62 2.8E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1015490 11f4f95ea664dd0eb328269c826310dd 292 Gene3D G3DSA:1.10.10.10 3 91 3.5E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015490 11f4f95ea664dd0eb328269c826310dd 292 SUPERFAMILY SSF46785 6 88 3.24E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1015490 11f4f95ea664dd0eb328269c826310dd 292 Pfam PF03466 LysR substrate binding domain 88 287 5.0E-40 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 SUPERFAMILY SSF54665 4 129 1.02E-28 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 Gene3D G3DSA:3.30.365.10 187 279 7.4E-43 T 13-10-2018 MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 129 1.0E-16 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 SUPERFAMILY SSF56003 175 738 8.9E-137 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 Gene3D G3DSA:3.30.365.20 405 739 5.9E-81 T 13-10-2018 MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 176 675 1.1E-97 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 Gene3D G3DSA:3.90.1170.50 1 133 8.4E-25 T 13-10-2018 MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 SMART SM01008 23 136 2.6E-17 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MADE_1014125 7c9b2c9b6b0e2424b1b919c6be760f7a 741 Gene3D G3DSA:3.30.365.10 176 385 7.4E-43 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 Gene3D G3DSA:3.50.50.60 7 386 5.0E-199 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 Gene3D G3DSA:3.30.70.20 451 544 1.3E-39 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 446 546 1.5E-51 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 SUPERFAMILY SSF54373 211 305 3.33E-35 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 Gene3D G3DSA:3.30.9.90 79 450 5.0E-199 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 SUPERFAMILY SSF54862 450 549 2.68E-29 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 SUPERFAMILY SSF51905 4 448 1.56E-56 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 4.5E-6 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 179 194 4.5E-6 T 13-10-2018 MADE_1013780 e3dfcba22e08fd67ee2554dda1f12ab7 549 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 57 1.5E-5 T 13-10-2018 MADE_1001320 11b4bcee97fdeb584d5eca618815fa12 1331 Pfam PF13502 AsmA-like C-terminal region 1046 1287 3.3E-47 T 13-10-2018 IPR032712 AsmA-like, C-terminal MADE_1001320 11b4bcee97fdeb584d5eca618815fa12 1331 Pfam PF13116 Protein of unknown function 503 786 5.7E-74 T 13-10-2018 IPR025263 Domain of unknown function DUF3971 MADE_1001320 11b4bcee97fdeb584d5eca618815fa12 1331 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 11 1296 8.8E-242 T 13-10-2018 IPR011836 Conserved hypothetical protein CHP02099 MADE_1007455 5c3e8a3725afe30af15db6721468c2ca 355 Gene3D G3DSA:3.40.50.300 26 184 6.2E-12 T 13-10-2018 MADE_1007455 5c3e8a3725afe30af15db6721468c2ca 355 TIGRFAM TIGR03015 pepcterm_ATPase: putative secretion ATPase, PEP-CTERM locus subfamily 1 268 7.5E-110 T 13-10-2018 IPR017466 ATPase, secretion system, PEP-CTERM, predicted MADE_1007455 5c3e8a3725afe30af15db6721468c2ca 355 SUPERFAMILY SSF52540 5 264 5.0E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007455 5c3e8a3725afe30af15db6721468c2ca 355 Pfam PF13401 AAA domain 42 170 9.6E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1007455 5c3e8a3725afe30af15db6721468c2ca 355 SMART SM00382 42 204 6.7E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004010 bc643d980b98133b5921b24a060d498d 240 Pfam PF13098 Thioredoxin-like domain 113 236 6.8E-28 T 13-10-2018 IPR012336 Thioredoxin-like fold MADE_1004010 bc643d980b98133b5921b24a060d498d 240 Gene3D G3DSA:3.40.30.10 84 239 3.6E-50 T 13-10-2018 MADE_1004010 bc643d980b98133b5921b24a060d498d 240 ProSitePatterns PS00194 Thioredoxin family active site. 120 138 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_1004010 bc643d980b98133b5921b24a060d498d 240 SUPERFAMILY SSF54423 27 84 3.73E-12 T 13-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 MADE_1004010 bc643d980b98133b5921b24a060d498d 240 SUPERFAMILY SSF52833 102 236 7.7E-36 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1004010 bc643d980b98133b5921b24a060d498d 240 Pfam PF10411 Disulfide bond isomerase protein N-terminus 33 83 4.3E-13 T 13-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal MADE_1004010 bc643d980b98133b5921b24a060d498d 240 Gene3D G3DSA:3.10.450.70 24 83 5.4E-19 T 13-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 MADE_1020535 3184a927d424d01f4e1b3abb907daf7a 160 SUPERFAMILY SSF89963 2 85 1.57E-28 T 13-10-2018 IPR036183 YajQ-like superfamily MADE_1020535 3184a927d424d01f4e1b3abb907daf7a 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 1.4E-62 T 13-10-2018 IPR007551 Protein of unknown function DUF520 MADE_1020535 3184a927d424d01f4e1b3abb907daf7a 160 Gene3D G3DSA:3.30.70.860 95 160 6.1E-30 T 13-10-2018 IPR035571 UPF0234-like, C-terminal MADE_1020535 3184a927d424d01f4e1b3abb907daf7a 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 28.298 T 13-10-2018 IPR007551 Protein of unknown function DUF520 MADE_1020535 3184a927d424d01f4e1b3abb907daf7a 160 Gene3D G3DSA:3.30.70.990 9 94 2.1E-25 T 13-10-2018 IPR035570 UPF0234, N-terminal MADE_1020535 3184a927d424d01f4e1b3abb907daf7a 160 SUPERFAMILY SSF89963 88 160 1.44E-29 T 13-10-2018 IPR036183 YajQ-like superfamily MADE_1011910 c8c9df94cbab8aed12ffcbd639ac7695 1373 Gene3D G3DSA:1.20.58.2200 1311 1372 4.7E-18 T 13-10-2018 IPR038440 FimV, C-terminal domain superfamily MADE_1011910 c8c9df94cbab8aed12ffcbd639ac7695 1373 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 53 125 2.7E-27 T 13-10-2018 IPR020012 Motility protein FimV, N-terminal MADE_1011910 c8c9df94cbab8aed12ffcbd639ac7695 1373 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 1329 1372 7.3E-17 T 13-10-2018 IPR020011 Motility protein FimV, C-terminal MADE_000001020985 7814e247de32a47d4d011b2c8b3fa6de 688 SUPERFAMILY SSF63825 406 658 1.03E-12 T 13-10-2018 MADE_000001020985 7814e247de32a47d4d011b2c8b3fa6de 688 Gene3D G3DSA:2.120.10.30 86 266 4.8E-7 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_000001020985 7814e247de32a47d4d011b2c8b3fa6de 688 SUPERFAMILY SSF75011 137 542 6.93E-12 T 13-10-2018 MADE_1013610 c83db3274d8087ca12873f29201917cb 290 Pfam PF00892 EamA-like transporter family 145 277 6.4E-19 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1013610 c83db3274d8087ca12873f29201917cb 290 SUPERFAMILY SSF103481 42 131 6.15E-5 T 13-10-2018 MADE_1013610 c83db3274d8087ca12873f29201917cb 290 SUPERFAMILY SSF103481 181 280 4.58E-11 T 13-10-2018 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 875 9.2E-36 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 334 2.2E-72 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SUPERFAMILY SSF52335 935 1070 3.53E-37 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.436 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SUPERFAMILY SSF52440 556 675 4.17E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.3E-64 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.3E-64 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.3E-64 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.3E-64 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 1.3E-64 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.3E-64 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.3E-64 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.14 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SUPERFAMILY SSF56059 128 401 1.94E-108 T 13-10-2018 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SUPERFAMILY SSF48108 396 554 2.09E-51 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SUPERFAMILY SSF52440 1 127 2.01E-50 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Gene3D G3DSA:1.10.1030.10 404 553 3.3E-49 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1052 0.0 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Gene3D G3DSA:3.30.470.20 119 403 1.2E-128 T 13-10-2018 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SMART SM00851 955 1041 1.4E-28 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Pfam PF02142 MGS-like domain 956 1041 1.2E-16 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Gene3D G3DSA:3.40.50.1380 936 1072 3.2E-36 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 3.2E-39 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Gene3D G3DSA:3.30.470.20 665 935 5.2E-123 T 13-10-2018 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Gene3D G3DSA:3.40.50.20 554 662 1.7E-49 T 13-10-2018 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SUPERFAMILY SSF56059 673 932 2.47E-104 T 13-10-2018 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 SMART SM01096 424 547 4.0E-73 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007095 ce33559add2ec1e91959b55d58d7f8e0 1073 Gene3D G3DSA:3.40.50.20 1 116 6.0E-50 T 13-10-2018 MADE_1007930 00ef463d2185c3f99ecd3029e689dfb6 313 Pfam PF13478 XdhC Rossmann domain 112 254 2.5E-34 T 13-10-2018 IPR027051 XdhC Rossmann domain MADE_1007930 00ef463d2185c3f99ecd3029e689dfb6 313 Gene3D G3DSA:3.40.50.720 111 258 1.1E-37 T 13-10-2018 MADE_1007930 00ef463d2185c3f99ecd3029e689dfb6 313 SUPERFAMILY SSF51735 97 196 8.08E-6 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1007930 00ef463d2185c3f99ecd3029e689dfb6 313 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 25 255 4.8E-84 T 13-10-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC MADE_1007930 00ef463d2185c3f99ecd3029e689dfb6 313 Pfam PF02625 XdhC and CoxI family 19 81 6.8E-19 T 13-10-2018 IPR003777 XdhC- CoxI MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 Pfam PF00563 EAL domain 208 441 1.4E-63 T 13-10-2018 IPR001633 EAL domain MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 27 189 3.4E-37 T 13-10-2018 IPR000160 GGDEF domain MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 SMART SM00267 19 191 4.1E-48 T 13-10-2018 IPR000160 GGDEF domain MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 Gene3D G3DSA:3.30.70.270 24 202 5.4E-48 T 13-10-2018 MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 SMART SM00052 201 446 5.7E-93 T 13-10-2018 IPR001633 EAL domain MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 Gene3D G3DSA:3.20.20.450 203 452 3.0E-82 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 Pfam PF00990 Diguanylate cyclase, GGDEF domain 30 186 1.2E-40 T 13-10-2018 IPR000160 GGDEF domain MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 SUPERFAMILY SSF55073 35 193 6.12E-41 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1016445 fbdbccac7a81aedaf2af35f23c93ecad 456 SUPERFAMILY SSF141868 208 451 8.76E-80 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1008355 8b97f5800e0a0240405962f715bc0eb0 269 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 MADE_1008355 8b97f5800e0a0240405962f715bc0eb0 269 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 266 5.0E-99 T 13-10-2018 MADE_1008355 8b97f5800e0a0240405962f715bc0eb0 269 Gene3D G3DSA:3.60.10.10 1 269 8.2E-79 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1008355 8b97f5800e0a0240405962f715bc0eb0 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 260 8.0E-18 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MADE_1008355 8b97f5800e0a0240405962f715bc0eb0 269 SUPERFAMILY SSF56219 1 268 2.22E-86 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1008355 8b97f5800e0a0240405962f715bc0eb0 269 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 267 3.2E-88 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 MADE_1000160 69814bb8f911bd497c978d7ffe720103 347 PIRSF PIRSF028458 1 347 1.6E-108 T 13-10-2018 IPR016886 Predicted glycerophosphotransferase UCP028458 MADE_1000160 69814bb8f911bd497c978d7ffe720103 347 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 154 257 5.6E-8 T 13-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 MADE_1000160 69814bb8f911bd497c978d7ffe720103 347 SUPERFAMILY SSF53756 13 318 8.63E-34 T 13-10-2018 MADE_1000160 69814bb8f911bd497c978d7ffe720103 347 Gene3D G3DSA:3.40.50.12580 148 258 2.7E-8 T 13-10-2018 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 351 362 6.2E-31 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 214 234 6.2E-31 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 92 106 6.2E-31 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 172 194 6.2E-31 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 PIRSF PIRSF000185 13 426 4.4E-151 T 13-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 181 423 5.1E-62 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 100 113 - T 13-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 Gene3D G3DSA:3.40.50.720 181 425 1.1E-76 T 13-10-2018 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 SMART SM00839 183 423 5.1E-76 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 Gene3D G3DSA:3.40.50.10860 37 180 7.8E-59 T 13-10-2018 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 36 162 3.1E-50 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 SUPERFAMILY SSF51735 181 424 5.21E-65 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1005625 67e31b0ceac092396b3160e3f15d7aeb 433 SUPERFAMILY SSF53223 16 183 1.12E-57 T 13-10-2018 MADE_1008845 c1c84a40ab7a103b8bebe6507ba52f05 476 Gene3D G3DSA:2.60.40.10 359 475 6.1E-34 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1008845 c1c84a40ab7a103b8bebe6507ba52f05 476 Pfam PF13746 4Fe-4S dicluster domain 220 329 4.0E-46 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MADE_1008845 c1c84a40ab7a103b8bebe6507ba52f05 476 SUPERFAMILY SSF54862 106 365 2.93E-29 T 13-10-2018 MADE_1008845 c1c84a40ab7a103b8bebe6507ba52f05 476 Pfam PF12801 4Fe-4S binding domain 96 138 3.0E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MADE_1008845 c1c84a40ab7a103b8bebe6507ba52f05 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 276 287 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MADE_1008845 c1c84a40ab7a103b8bebe6507ba52f05 476 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 45 475 5.3E-163 T 13-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 MADE_1008845 c1c84a40ab7a103b8bebe6507ba52f05 476 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 359 475 4.2E-29 T 13-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Gene3D G3DSA:3.30.830.10 752 949 5.7E-36 T 13-10-2018 MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Gene3D G3DSA:3.30.830.10 285 478 4.8E-32 T 13-10-2018 MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Gene3D G3DSA:3.30.830.10 536 745 9.6E-42 T 13-10-2018 MADE_1013235 39226863a04ec3579959f22cf6c62422 963 SUPERFAMILY SSF63411 757 961 8.83E-39 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1013235 39226863a04ec3579959f22cf6c62422 963 SUPERFAMILY SSF63411 55 274 5.76E-49 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Gene3D G3DSA:3.30.830.10 55 278 1.0E-61 T 13-10-2018 MADE_1013235 39226863a04ec3579959f22cf6c62422 963 SUPERFAMILY SSF63411 531 734 1.55E-42 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Pfam PF00675 Insulinase (Peptidase family M16) 69 157 1.2E-14 T 13-10-2018 IPR011765 Peptidase M16, N-terminal MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Pfam PF00675 Insulinase (Peptidase family M16) 552 673 5.3E-12 T 13-10-2018 IPR011765 Peptidase M16, N-terminal MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Pfam PF05193 Peptidase M16 inactive domain 227 403 5.1E-26 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_1013235 39226863a04ec3579959f22cf6c62422 963 Pfam PF05193 Peptidase M16 inactive domain 699 868 1.5E-16 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_1013235 39226863a04ec3579959f22cf6c62422 963 SUPERFAMILY SSF63411 293 474 4.67E-29 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 157 371 2.1E-54 T 13-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 Pfam PF01872 RibD C-terminal domain 158 368 4.9E-47 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 111 4.6E-23 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 PIRSF PIRSF006769 4 373 1.1E-121 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 13 368 3.0E-114 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 57 99 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 Gene3D G3DSA:3.40.140.10 1 151 1.7E-48 T 13-10-2018 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 SUPERFAMILY SSF53927 9 153 1.47E-47 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 Gene3D G3DSA:3.40.430.10 152 377 6.2E-65 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MADE_1012450 8b2a54dd43e3434dd040be82f188274a 379 SUPERFAMILY SSF53597 155 369 2.78E-53 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MADE_1009420 abdae96520eeac8c2eb92dfadecdfd54 248 SUPERFAMILY SSF53448 3 244 1.22E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1009420 abdae96520eeac8c2eb92dfadecdfd54 248 Gene3D G3DSA:3.90.550.10 1 248 4.1E-87 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1009420 abdae96520eeac8c2eb92dfadecdfd54 248 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 248 41.947 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MADE_1009420 abdae96520eeac8c2eb92dfadecdfd54 248 Pfam PF02348 Cytidylyltransferase 5 222 4.2E-60 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MADE_1009420 abdae96520eeac8c2eb92dfadecdfd54 248 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 242 9.4E-97 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 SMART SM00382 161 304 2.1E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 SUPERFAMILY SSF46689 381 468 7.17E-20 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 Gene3D G3DSA:1.10.10.60 385 469 3.6E-23 T 13-10-2018 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 Gene3D G3DSA:3.40.50.300 126 312 3.3E-67 T 13-10-2018 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 469 4.2E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 4.2E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 Pfam PF00158 Sigma-54 interaction domain 141 307 5.3E-71 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 Gene3D G3DSA:1.10.8.60 313 384 6.0E-22 T 13-10-2018 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 SUPERFAMILY SSF52540 140 384 2.58E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 SUPERFAMILY SSF52172 1 186 1.32E-40 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 Gene3D G3DSA:3.40.50.2300 1 125 1.7E-36 T 13-10-2018 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 SMART SM00448 4 116 2.0E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 Pfam PF00072 Response regulator receiver domain 6 114 1.2E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 466 1.1E-228 T 13-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 MADE_1016000 9eb64e3dbb5a3347670adae2dbf8b2cd 469 Pfam PF02954 Bacterial regulatory protein, Fis family 429 466 9.3E-15 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 PRINTS PR00773 GrpE protein signature 70 86 4.7E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 PRINTS PR00773 GrpE protein signature 180 199 4.7E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 PRINTS PR00773 GrpE protein signature 98 113 4.7E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 PRINTS PR00773 GrpE protein signature 153 168 4.7E-27 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 Gene3D G3DSA:2.30.22.10 145 201 1.2E-25 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 Gene3D G3DSA:3.90.20.20 38 144 2.1E-32 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 SUPERFAMILY SSF58014 48 145 5.62E-29 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 SUPERFAMILY SSF51064 147 202 1.14E-19 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 Pfam PF01025 GrpE 41 200 2.0E-54 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 Hamap MF_01151 Protein GrpE [grpE]. 6 201 21.873 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MADE_1007050 a6ca6eb7d4ef1174b4c066bed0e9fcef 211 ProSitePatterns PS01071 grpE protein signature. 156 199 - T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 MADE_1016690 0abaf696c9ffd99c82778775df37ac72 365 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 2 364 43.008 T 13-10-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 MADE_1016690 0abaf696c9ffd99c82778775df37ac72 365 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 8 364 3.2E-167 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MADE_1016690 0abaf696c9ffd99c82778775df37ac72 365 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 297 326 - T 13-10-2018 IPR030390 RNA methyltransferase TrmA, active site MADE_1016690 0abaf696c9ffd99c82778775df37ac72 365 Gene3D G3DSA:3.40.1350.30 43 187 1.2E-132 T 13-10-2018 MADE_1016690 0abaf696c9ffd99c82778775df37ac72 365 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 9 364 1.1E-165 T 13-10-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 MADE_1016690 0abaf696c9ffd99c82778775df37ac72 365 SUPERFAMILY SSF53335 8 363 3.95E-54 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1016690 0abaf696c9ffd99c82778775df37ac72 365 Gene3D G3DSA:3.40.50.150 11 360 1.2E-132 T 13-10-2018 MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 Pfam PF00437 Type II/IV secretion system protein 382 642 2.2E-73 T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 SMART SM00065 34 196 3.7E-5 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 SMART SM00382 503 628 5.5E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 SUPERFAMILY SSF160246 201 330 1.18E-7 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 Pfam PF01590 GAF domain 59 182 2.7E-9 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 SUPERFAMILY SSF52540 359 754 2.2E-91 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 SUPERFAMILY SSF55781 29 185 5.23E-26 T 13-10-2018 MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 570 584 - T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 Gene3D G3DSA:3.30.450.40 23 191 6.3E-29 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 231 336 8.2E-9 T 13-10-2018 IPR007831 General secretory system II, protein E, N-terminal MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 Gene3D G3DSA:3.30.450.90 341 476 8.5E-42 T 13-10-2018 MADE_1002250 80d1a23c42e79dfb3a29778f64f2c7f4 760 Gene3D G3DSA:3.40.50.300 478 758 2.9E-102 T 13-10-2018 MADE_000001022825 063a02f1d12883635e3326d95856a0a8 435 PIRSF PIRSF006060 1 433 6.7E-56 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MADE_000001022825 063a02f1d12883635e3326d95856a0a8 435 Gene3D G3DSA:1.20.1740.10 9 435 1.1E-64 T 13-10-2018 MADE_000001022825 063a02f1d12883635e3326d95856a0a8 435 Pfam PF13520 Amino acid permease 13 396 4.9E-31 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 Gene3D G3DSA:1.10.287.180 1 75 8.2E-31 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 SUPERFAMILY SSF54534 82 157 2.35E-25 T 13-10-2018 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 Gene3D G3DSA:3.10.50.30 76 158 3.9E-32 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 SUPERFAMILY SSF46557 3 78 7.46E-28 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.764 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 PIRSF PIRSF006092 1 158 5.5E-54 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 2.6E-30 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 7.9E-60 T 13-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 MADE_1007100 cc0fb40596cd06724850c4b087c3b26c 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 6.7E-30 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MADE_1004755 5cdc966f5832f173e5633c3e0f0374e6 861 Pfam PF02120 Flagellar hook-length control protein FliK 769 843 1.1E-8 T 13-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 Gene3D G3DSA:3.40.50.12740 8 210 4.9E-66 T 13-10-2018 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 SMART SM00448 7 120 2.6E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 6.0E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 6.0E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 6.0E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 SMART SM00421 153 210 1.4E-22 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 SUPERFAMILY SSF46894 149 209 1.26E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 SUPERFAMILY SSF52172 6 134 2.99E-34 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 Pfam PF00072 Response regulator receiver domain 9 120 3.6E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1019305 6a98d3491675a964bc4815e6af52af8f 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 7.7E-22 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 257 290 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 SMART SM00852 184 321 5.1E-45 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 SUPERFAMILY SSF53218 181 325 7.33E-46 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 2.4E-36 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 SUPERFAMILY SSF63882 8 180 2.62E-58 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 SUPERFAMILY SSF63867 333 409 1.83E-20 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 Gene3D G3DSA:3.40.980.10 179 330 6.2E-145 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 Gene3D G3DSA:2.170.190.11 54 145 6.2E-145 T 13-10-2018 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 Gene3D G3DSA:3.90.105.10 31 178 6.2E-145 T 13-10-2018 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 Pfam PF03453 MoeA N-terminal region (domain I and II) 12 171 8.1E-46 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 Gene3D G3DSA:2.40.340.10 331 401 6.2E-145 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 Pfam PF00994 Probable molybdopterin binding domain 185 319 6.3E-31 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1019310 d46ffe052277d8c85768d513ba06b7eb 411 Pfam PF03454 MoeA C-terminal region (domain IV) 334 404 1.5E-15 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1004820 72baf8fd24bebafae5b986e68500be91 506 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 148 160 - T 13-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MADE_1004820 72baf8fd24bebafae5b986e68500be91 506 SUPERFAMILY SSF103473 11 302 2.62E-25 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1004820 72baf8fd24bebafae5b986e68500be91 506 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 8 491 3.2E-113 T 13-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 MADE_1004820 72baf8fd24bebafae5b986e68500be91 506 Gene3D G3DSA:1.20.1250.20 1 496 4.3E-128 T 13-10-2018 MADE_1004820 72baf8fd24bebafae5b986e68500be91 506 SUPERFAMILY SSF103473 322 495 9.81E-11 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1004820 72baf8fd24bebafae5b986e68500be91 506 Pfam PF00854 POT family 87 459 1.1E-59 T 13-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 MADE_1004820 72baf8fd24bebafae5b986e68500be91 506 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 75 99 - T 13-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 MADE_1002755 6bce12402f7ec4d00daac9b566d7aa48 347 Gene3D G3DSA:1.10.40.50 274 343 4.4E-23 T 13-10-2018 MADE_1002755 6bce12402f7ec4d00daac9b566d7aa48 347 Gene3D G3DSA:3.40.50.300 102 273 2.2E-49 T 13-10-2018 MADE_1002755 6bce12402f7ec4d00daac9b566d7aa48 347 SUPERFAMILY SSF52540 113 337 8.34E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002755 6bce12402f7ec4d00daac9b566d7aa48 347 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 41 338 36.511 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MADE_1002755 6bce12402f7ec4d00daac9b566d7aa48 347 Pfam PF03193 RsgA GTPase 99 274 1.4E-56 T 13-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 MADE_1002755 6bce12402f7ec4d00daac9b566d7aa48 347 Gene3D G3DSA:2.40.50.140 39 101 1.3E-20 T 13-10-2018 MADE_1002755 6bce12402f7ec4d00daac9b566d7aa48 347 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 74 331 7.9E-86 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 MADE_1015310 53be467befb48ea634c6b69edec195e3 280 SUPERFAMILY SSF82689 178 276 6.93E-35 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1015310 53be467befb48ea634c6b69edec195e3 280 SUPERFAMILY SSF50182 110 176 9.48E-17 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1015310 53be467befb48ea634c6b69edec195e3 280 Pfam PF00924 Mechanosensitive ion channel 69 265 4.0E-56 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1015310 53be467befb48ea634c6b69edec195e3 280 SUPERFAMILY SSF82861 25 109 1.01E-17 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MADE_1015310 53be467befb48ea634c6b69edec195e3 280 Gene3D G3DSA:2.30.30.60 126 175 1.8E-21 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1015310 53be467befb48ea634c6b69edec195e3 280 Gene3D G3DSA:3.30.70.100 177 270 5.7E-29 T 13-10-2018 MADE_1015850 9eeee9d2e975dbfcf293c2d0abc0aacf 441 Pfam PF08525 Opacity-associated protein A N-terminal motif 13 40 3.3E-6 T 13-10-2018 IPR013731 Opacity-associated protein A, N-terminal MADE_1015850 9eeee9d2e975dbfcf293c2d0abc0aacf 441 Pfam PF04225 Opacity-associated protein A LysM-like domain 81 154 7.2E-10 T 13-10-2018 IPR007340 Opacity-associated protein A MADE_1015850 9eeee9d2e975dbfcf293c2d0abc0aacf 441 Gene3D G3DSA:3.10.450.350 71 159 3.1E-15 T 13-10-2018 MADE_1015850 9eeee9d2e975dbfcf293c2d0abc0aacf 441 Gene3D G3DSA:2.70.70.10 277 406 2.6E-78 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1015850 9eeee9d2e975dbfcf293c2d0abc0aacf 441 SUPERFAMILY SSF51261 163 401 8.37E-66 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1015850 9eeee9d2e975dbfcf293c2d0abc0aacf 441 Pfam PF01551 Peptidase family M23 306 400 2.1E-27 T 13-10-2018 IPR016047 Peptidase M23 MADE_1015850 9eeee9d2e975dbfcf293c2d0abc0aacf 441 Gene3D G3DSA:3.10.450.350 184 420 2.6E-78 T 13-10-2018 MADE_1007940 b987e4395a269988f28ac932389481fa 480 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 2 465 1.1E-165 T 13-10-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 MADE_1007940 b987e4395a269988f28ac932389481fa 480 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 193 356 1.5E-47 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 MADE_1007940 b987e4395a269988f28ac932389481fa 480 Gene3D G3DSA:3.30.465.10 193 357 8.9E-51 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1007940 b987e4395a269988f28ac932389481fa 480 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MADE_1007940 b987e4395a269988f28ac932389481fa 480 SUPERFAMILY SSF56176 190 356 2.13E-48 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_1007940 b987e4395a269988f28ac932389481fa 480 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 365 465 3.9E-23 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MADE_1007940 b987e4395a269988f28ac932389481fa 480 SUPERFAMILY SSF54292 2 88 1.57E-17 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_1007940 b987e4395a269988f28ac932389481fa 480 Pfam PF01799 [2Fe-2S] binding domain 85 155 1.7E-31 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MADE_1007940 b987e4395a269988f28ac932389481fa 480 Gene3D G3DSA:1.10.150.120 88 192 1.7E-34 T 13-10-2018 MADE_1007940 b987e4395a269988f28ac932389481fa 480 Gene3D G3DSA:3.10.20.30 1 87 1.9E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1007940 b987e4395a269988f28ac932389481fa 480 SUPERFAMILY SSF47741 93 180 6.54E-35 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MADE_1007940 b987e4395a269988f28ac932389481fa 480 SMART SM01092 364 466 2.9E-22 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MADE_1007940 b987e4395a269988f28ac932389481fa 480 SUPERFAMILY SSF55447 361 469 2.35E-24 T 13-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily MADE_1007940 b987e4395a269988f28ac932389481fa 480 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 74 8.3E-6 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MADE_1007940 b987e4395a269988f28ac932389481fa 480 Gene3D G3DSA:3.30.390.50 364 467 1.6E-22 T 13-10-2018 MADE_1007940 b987e4395a269988f28ac932389481fa 480 PIRSF PIRSF036557 1 479 1.4E-170 T 13-10-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria MADE_1003470 f7859978ec842f67d317e50da894e844 325 Gene3D G3DSA:3.30.70.270 148 323 2.9E-57 T 13-10-2018 MADE_1003470 f7859978ec842f67d317e50da894e844 325 Pfam PF08448 PAS fold 21 142 6.7E-6 T 13-10-2018 IPR013656 PAS fold-4 MADE_1003470 f7859978ec842f67d317e50da894e844 325 SUPERFAMILY SSF55785 20 132 2.28E-9 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1003470 f7859978ec842f67d317e50da894e844 325 SMART SM00267 148 320 6.7E-61 T 13-10-2018 IPR000160 GGDEF domain MADE_1003470 f7859978ec842f67d317e50da894e844 325 SUPERFAMILY SSF55073 164 321 3.22E-51 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1003470 f7859978ec842f67d317e50da894e844 325 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 156 319 1.1E-53 T 13-10-2018 IPR000160 GGDEF domain MADE_1003470 f7859978ec842f67d317e50da894e844 325 Pfam PF00990 Diguanylate cyclase, GGDEF domain 160 316 1.8E-46 T 13-10-2018 IPR000160 GGDEF domain MADE_1003470 f7859978ec842f67d317e50da894e844 325 Gene3D G3DSA:3.30.450.20 18 143 7.4E-35 T 13-10-2018 MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 Pfam PF00672 HAMP domain 192 236 1.5E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 513 602 2.0E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 SMART SM00304 188 240 6.2E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 Gene3D G3DSA:1.10.287.130 186 274 7.3E-8 T 13-10-2018 MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 SUPERFAMILY SSF158472 188 237 2.35E-8 T 13-10-2018 MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 SMART SM00387 512 606 2.0E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 SUPERFAMILY SSF55874 479 602 8.38E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 Gene3D G3DSA:1.20.120.960 43 160 7.2E-9 T 13-10-2018 MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 Pfam PF07730 Histidine kinase 405 471 1.1E-14 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 Gene3D G3DSA:3.30.565.10 471 605 1.7E-24 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 38 125 2.8E-11 T 13-10-2018 IPR029095 NarX-like, N-terminal MADE_1019280 6a464876068f3f70ce573d2527cdfc0f 617 PIRSF PIRSF003167 3 617 6.3E-169 T 13-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 MADE_000001020890 526f81130f2ac613370375ceedab2520 525 Pfam PF13007 Transposase C of IS166 homeodomain 27 86 5.8E-10 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain MADE_000001020890 526f81130f2ac613370375ceedab2520 525 Pfam PF13817 IS66 C-terminal element 466 502 4.3E-11 T 13-10-2018 IPR039552 Transposase IS66, C-terminal MADE_000001020890 526f81130f2ac613370375ceedab2520 525 Pfam PF03050 Transposase IS66 family 172 459 6.7E-76 T 13-10-2018 IPR004291 Transposase, IS66 MADE_1015255 4619d8cabb95e891f610bfca2b012dd6 231 SUPERFAMILY SSF52540 1 212 1.19E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015255 4619d8cabb95e891f610bfca2b012dd6 231 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 180 3.3E-12 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain MADE_1015255 4619d8cabb95e891f610bfca2b012dd6 231 PIRSF PIRSF009320 1 220 4.5E-38 T 13-10-2018 MADE_1015255 4619d8cabb95e891f610bfca2b012dd6 231 Gene3D G3DSA:3.40.50.300 1 212 5.2E-46 T 13-10-2018 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Gene3D G3DSA:1.10.10.10 450 526 4.8E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 373 598 8.5E-37 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 SUPERFAMILY SSF88659 507 609 3.05E-25 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Pfam PF04546 Sigma-70, non-essential region 137 346 2.2E-68 T 13-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 570 596 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 401 414 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 PRINTS PR00046 Major sigma-70 factor signature 401 414 6.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 PRINTS PR00046 Major sigma-70 factor signature 549 561 6.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 PRINTS PR00046 Major sigma-70 factor signature 570 585 6.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 PRINTS PR00046 Major sigma-70 factor signature 425 433 6.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 PRINTS PR00046 Major sigma-70 factor signature 585 596 6.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Gene3D G3DSA:1.10.220.120 1 64 5.1E-29 T 13-10-2018 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Gene3D G3DSA:1.10.10.10 527 611 1.6E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Pfam PF04545 Sigma-70, region 4 545 598 1.0E-18 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Pfam PF04542 Sigma-70 region 2 377 446 1.7E-21 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 SUPERFAMILY SSF88659 450 523 5.23E-20 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 610 46.371 T 13-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Gene3D G3DSA:1.10.601.10 111 446 1.1E-140 T 13-10-2018 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Pfam PF03979 Sigma-70 factor, region 1.1 4 79 1.6E-29 T 13-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 SUPERFAMILY SSF88946 113 444 7.06E-102 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Pfam PF04539 Sigma-70 region 3 456 531 2.3E-28 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 Pfam PF00140 Sigma-70 factor, region 1.2 96 126 4.4E-13 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_000001020785 a5e3366346ccf7a7cdc498851f83ff7d 611 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 373 609 2.0E-120 T 13-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Gene3D G3DSA:1.10.287.130 749 847 7.9E-14 T 13-10-2018 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Gene3D G3DSA:1.20.1730.10 31 532 8.4E-17 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 SUPERFAMILY SSF52172 1018 1142 3.27E-23 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 SMART SM00388 784 849 9.6E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Pfam PF12860 PAS fold 616 729 2.5E-42 T 13-10-2018 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 SMART SM00387 893 1001 3.5E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Pfam PF00512 His Kinase A (phospho-acceptor) domain 784 849 2.2E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Pfam PF00072 Response regulator receiver domain 1022 1134 4.7E-16 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 894 999 1.1E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 SMART SM00448 1020 1134 1.3E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Gene3D G3DSA:3.40.50.2300 1014 1146 1.5E-22 T 13-10-2018 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Gene3D G3DSA:3.30.450.20 596 737 1.4E-9 T 13-10-2018 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 SUPERFAMILY SSF55874 839 998 1.57E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 Gene3D G3DSA:3.30.565.10 848 1002 5.0E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 SUPERFAMILY SSF47384 770 850 2.75E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 929 943 1.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 961 979 1.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 985 998 1.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 PRINTS PR00344 Bacterial sensor protein C-terminal signature 947 957 1.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001023100 6107ff4d6a4713bab092513f058bb3e8 1147 SUPERFAMILY SSF55785 622 734 5.12E-6 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 1.6E-89 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 54 647 4.6E-242 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 644 9.6E-124 T 13-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 3.8E-51 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 3.8E-51 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 3.8E-51 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 3.8E-51 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 3.8E-51 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 637 650 3.8E-51 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 3.8E-51 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004785 a0052f20fd5bec03653592a9b7c9db1f 685 Pfam PF01578 Cytochrome C assembly protein 89 296 3.2E-52 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MADE_1013360 4db97f952eb974c5128984377344de90 315 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 289 2.0E-69 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MADE_1013360 4db97f952eb974c5128984377344de90 315 Gene3D G3DSA:2.40.100.10 179 312 1.4E-37 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1013360 4db97f952eb974c5128984377344de90 315 SUPERFAMILY SSF50891 183 296 1.78E-5 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1013360 4db97f952eb974c5128984377344de90 315 SMART SM00797 24 306 6.8E-84 T 13-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Gene3D G3DSA:4.10.320.10 246 288 2.5E-17 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 SUPERFAMILY SSF52777 314 550 5.34E-72 T 13-10-2018 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 SUPERFAMILY SSF47005 247 286 3.01E-12 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Gene3D G3DSA:2.40.50.100 2 100 9.2E-23 T 13-10-2018 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Gene3D G3DSA:3.30.559.10 304 550 1.1E-81 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 SUPERFAMILY SSF51230 118 205 7.98E-24 T 13-10-2018 IPR011053 Single hybrid motif MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Pfam PF02817 e3 binding domain 249 283 1.9E-16 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Pfam PF00364 Biotin-requiring enzyme 119 190 5.4E-17 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Pfam PF00364 Biotin-requiring enzyme 4 75 1.9E-17 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 SUPERFAMILY SSF51230 1 93 1.02E-24 T 13-10-2018 IPR011053 Single hybrid motif MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 320 550 5.4E-79 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 Gene3D G3DSA:2.40.50.100 115 206 9.2E-21 T 13-10-2018 MADE_1009910 a7d19571ab9da01ed375b461e62480ab 553 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 142 171 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 Gene3D G3DSA:3.30.390.10 19 382 7.1E-145 T 13-10-2018 IPR029017 Enolase-like, N-terminal MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 SUPERFAMILY SSF54826 1 122 3.83E-31 T 13-10-2018 MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 SUPERFAMILY SSF51604 106 385 1.63E-74 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 Gene3D G3DSA:3.20.20.120 111 372 7.1E-145 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 22 118 2.5E-19 T 13-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 SMART SM00922 146 260 1.1E-9 T 13-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 Pfam PF13378 Enolase C-terminal domain-like 150 380 2.7E-49 T 13-10-2018 IPR029065 Enolase C-terminal domain-like MADE_1008815 23ac1e9adfadb9e979842fb376d07f91 394 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 93 118 - T 13-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 MADE_1003430 ffe416467be33afd40cbd5476483ada2 360 Gene3D G3DSA:1.10.10.60 260 360 1.3E-6 T 13-10-2018 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 Gene3D G3DSA:1.25.40.10 135 406 1.8E-34 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SUPERFAMILY SSF52540 403 639 1.59E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SMART SM00028 214 244 140.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SMART SM00028 43 76 41.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SMART SM00028 177 210 40.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SMART SM00028 350 383 290.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SMART SM00028 279 312 7.4E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SMART SM00028 245 278 15.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SMART SM00028 77 110 2.1 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 Pfam PF13469 Sulfotransferase family 418 604 2.8E-42 T 13-10-2018 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 Gene3D G3DSA:1.25.40.10 10 134 9.0E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 Pfam PF13432 Tetratricopeptide repeat 250 307 1.1E-8 T 13-10-2018 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 Pfam PF13432 Tetratricopeptide repeat 150 210 0.0011 T 13-10-2018 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 Gene3D G3DSA:3.40.50.300 407 649 6.4E-59 T 13-10-2018 MADE_1008585 5c0e078116f24dcd71a9d3ff31ef3536 652 SUPERFAMILY SSF48452 44 322 2.02E-35 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1015285 6e8af5759ebf21c09b1dd8a7fa8e9e1e 374 Gene3D G3DSA:3.40.47.10 219 374 7.8E-38 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1015285 6e8af5759ebf21c09b1dd8a7fa8e9e1e 374 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 283 372 3.8E-19 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MADE_1015285 6e8af5759ebf21c09b1dd8a7fa8e9e1e 374 SUPERFAMILY SSF53901 3 373 4.74E-50 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1015285 6e8af5759ebf21c09b1dd8a7fa8e9e1e 374 Gene3D G3DSA:3.40.47.10 1 214 1.3E-54 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1015285 6e8af5759ebf21c09b1dd8a7fa8e9e1e 374 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 151 218 4.3E-15 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 MADE_1018250 dfe679180f8720b8980994599f98c123 417 Gene3D G3DSA:2.40.50.100 79 102 3.4E-5 T 13-10-2018 MADE_1018250 dfe679180f8720b8980994599f98c123 417 Gene3D G3DSA:2.40.30.170 298 346 1.0E-10 T 13-10-2018 MADE_1018250 dfe679180f8720b8980994599f98c123 417 Gene3D G3DSA:1.10.287.470 201 235 1.0E-10 T 13-10-2018 MADE_1018250 dfe679180f8720b8980994599f98c123 417 Pfam PF13437 HlyD family secretion protein 265 363 8.7E-12 T 13-10-2018 MADE_1018250 dfe679180f8720b8980994599f98c123 417 Gene3D G3DSA:1.10.287.470 103 161 3.4E-5 T 13-10-2018 MADE_1018250 dfe679180f8720b8980994599f98c123 417 Gene3D G3DSA:2.40.50.100 236 297 1.0E-10 T 13-10-2018 MADE_1018250 dfe679180f8720b8980994599f98c123 417 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 81 101 1.1E-17 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1018250 dfe679180f8720b8980994599f98c123 417 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 400 417 1.1E-17 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1018250 dfe679180f8720b8980994599f98c123 417 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 277 298 1.1E-17 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1018250 dfe679180f8720b8980994599f98c123 417 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 385 400 1.1E-17 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1018250 dfe679180f8720b8980994599f98c123 417 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 310 334 1.1E-17 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 Pfam PF01795 MraW methylase family 6 312 1.9E-116 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 PIRSF PIRSF004486 3 313 3.9E-106 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 SUPERFAMILY SSF53335 9 313 1.53E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 Gene3D G3DSA:3.40.50.150 12 312 6.3E-107 T 13-10-2018 MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 Gene3D G3DSA:1.10.150.170 115 217 6.3E-107 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 SUPERFAMILY SSF81799 117 216 2.88E-34 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 9 313 38.68 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MADE_1015190 c20756e79376713e2e195e9a80c0a7a7 313 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 5 312 2.0E-124 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 MADE_000001022770 d8073a17aef32df5fcaceb0f1a98ccf0 758 Gene3D G3DSA:2.60.120.260 20 154 1.4E-25 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_000001022770 d8073a17aef32df5fcaceb0f1a98ccf0 758 Pfam PF03170 Bacterial cellulose synthase subunit 22 653 4.1E-76 T 13-10-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 MADE_000001022770 d8073a17aef32df5fcaceb0f1a98ccf0 758 PRINTS PR01440 Cellulose synthase subunit B signature 505 524 7.2E-6 T 13-10-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 MADE_000001022770 d8073a17aef32df5fcaceb0f1a98ccf0 758 PRINTS PR01440 Cellulose synthase subunit B signature 307 328 7.2E-6 T 13-10-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 MADE_000001022770 d8073a17aef32df5fcaceb0f1a98ccf0 758 Gene3D G3DSA:2.60.120.260 356 499 4.3E-30 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1000595 18fd996afed2be437388a6ac7a9f0c39 373 Gene3D G3DSA:3.90.1150.10 2 367 3.9E-120 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1000595 18fd996afed2be437388a6ac7a9f0c39 373 SUPERFAMILY SSF53383 1 371 1.02E-87 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1000595 18fd996afed2be437388a6ac7a9f0c39 373 Gene3D G3DSA:3.40.640.10 59 236 3.9E-120 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1000595 18fd996afed2be437388a6ac7a9f0c39 373 Gene3D G3DSA:1.10.260.50 13 278 3.9E-120 T 13-10-2018 MADE_1000595 18fd996afed2be437388a6ac7a9f0c39 373 Pfam PF00266 Aminotransferase class-V 2 362 2.0E-65 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_1000595 18fd996afed2be437388a6ac7a9f0c39 373 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MADE_1000595 18fd996afed2be437388a6ac7a9f0c39 373 PIRSF PIRSF005572 1 373 8.7E-112 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MADE_1018500 2d720839596ca201eae71328cb7940d9 392 Gene3D G3DSA:3.30.1150.10 60 161 8.5E-24 T 13-10-2018 MADE_1018500 2d720839596ca201eae71328cb7940d9 392 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 84 159 1.8E-17 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 MADE_1018500 2d720839596ca201eae71328cb7940d9 392 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 84 150 4.1E-13 T 13-10-2018 IPR006260 TonB/TolA, C-terminal MADE_1018500 2d720839596ca201eae71328cb7940d9 392 SUPERFAMILY SSF74653 76 153 5.49E-21 T 13-10-2018 MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 SUPERFAMILY SSF54211 202 328 4.55E-32 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 Gene3D G3DSA:3.30.230.10 216 328 9.3E-34 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 13-10-2018 IPR014762 DNA mismatch repair, conserved site MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 309 5.0E-99 T 13-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 121 8.6E-15 T 13-10-2018 MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 SUPERFAMILY SSF118116 453 546 3.4E-6 T 13-10-2018 IPR037198 MutL, C-terminal domain superfamily MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 SUPERFAMILY SSF55874 2 203 1.2E-54 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 SMART SM01340 211 329 1.4E-47 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 212 328 1.4E-33 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 605 22.278 T 13-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 MADE_000001023560 65be63947d5f0f93ad59c1e9820d5c64 608 Gene3D G3DSA:3.30.565.10 1 211 3.8E-72 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1000515 80a4ff38164de30cc1e86f7f4ac9c1f2 586 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 67 519 4.7E-145 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MADE_1000515 80a4ff38164de30cc1e86f7f4ac9c1f2 586 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 29 519 8.5E-163 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MADE_1000515 80a4ff38164de30cc1e86f7f4ac9c1f2 586 ProSitePatterns PS01303 BCCT family of transporters signature. 337 346 - T 13-10-2018 IPR018093 BCCT transporter, conserved site MADE_1005370 476142f7b38fd1240bead17b07296e51 149 Gene3D G3DSA:3.10.129.10 3 148 1.6E-59 T 13-10-2018 MADE_1005370 476142f7b38fd1240bead17b07296e51 149 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 8 147 35.609 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_1005370 476142f7b38fd1240bead17b07296e51 149 SUPERFAMILY SSF54637 8 146 4.42E-48 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1005370 476142f7b38fd1240bead17b07296e51 149 Pfam PF07977 FabA-like domain 17 139 5.2E-35 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_1005370 476142f7b38fd1240bead17b07296e51 149 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 8 145 1.1E-59 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_1018490 ba88cb479859d755a1c6568c4eea76f2 226 Gene3D G3DSA:2.60.120.620 1 177 2.2E-39 T 13-10-2018 MADE_1018490 ba88cb479859d755a1c6568c4eea76f2 226 SMART SM00702 1 176 3.3E-10 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MADE_1018490 ba88cb479859d755a1c6568c4eea76f2 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 37.872 T 13-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 MADE_1018490 ba88cb479859d755a1c6568c4eea76f2 226 Gene3D G3DSA:4.10.860.20 179 226 2.5E-10 T 13-10-2018 MADE_1018490 ba88cb479859d755a1c6568c4eea76f2 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 83 175 2.1E-15 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 SUPERFAMILY SSF53790 20 238 1.16E-79 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 21 288 6.9E-87 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 98 109 - T 13-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 Gene3D G3DSA:3.30.950.10 128 247 3.9E-39 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 20 218 6.5E-29 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 Gene3D G3DSA:3.40.1010.10 6 127 1.4E-43 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 20 240 36.343 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MADE_1015615 ee369154b9aefe4d08b2bb694622071a 292 PIRSF PIRSF005917 8 292 3.9E-100 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 MADE_1004085 6f9a7286eefea199f937794189c5af42 504 Pfam PF00501 AMP-binding enzyme 8 373 6.3E-52 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_1004085 6f9a7286eefea199f937794189c5af42 504 Gene3D G3DSA:3.40.50.12780 1 367 1.0E-60 T 13-10-2018 MADE_1004085 6f9a7286eefea199f937794189c5af42 504 SUPERFAMILY SSF56801 6 480 2.22E-75 T 13-10-2018 MADE_1004085 6f9a7286eefea199f937794189c5af42 504 Gene3D G3DSA:3.30.300.30 371 478 4.2E-5 T 13-10-2018 MADE_1004085 6f9a7286eefea199f937794189c5af42 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 139 150 - T 13-10-2018 IPR020845 AMP-binding, conserved site MADE_000001021295 b83a4f0d685217a55df6c339b71bba8a 440 SUPERFAMILY SSF56935 67 414 2.45E-16 T 13-10-2018 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 PIRSF PIRSF036389 1 753 1.2E-227 T 13-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 SUPERFAMILY SSF56003 23 244 7.67E-34 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Gene3D G3DSA:3.90.1170.50 180 297 7.3E-10 T 13-10-2018 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 8 25 4.9E-5 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Gene3D G3DSA:3.30.365.10 328 548 1.2E-45 T 13-10-2018 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Gene3D G3DSA:3.30.365.10 601 751 2.3E-36 T 13-10-2018 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 618 701 1.0E-14 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 47 194 5.6E-15 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 320 603 4.7E-29 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 SUPERFAMILY SSF56003 323 747 2.33E-107 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 SMART SM01008 211 300 5.9E-18 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Gene3D G3DSA:3.30.365.10 47 179 2.6E-21 T 13-10-2018 MADE_000001021645 7a2b8cf0b4887aecdb39a50931a65cd8 753 Gene3D G3DSA:3.30.365.10 352 443 1.2E-45 T 13-10-2018 MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 4 254 6.9E-103 T 13-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 253 5.9E-53 T 13-10-2018 MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.4E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.4E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.4E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.4E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.4E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 4.4E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 Gene3D G3DSA:3.40.50.720 1 255 1.8E-75 T 13-10-2018 MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 SUPERFAMILY SSF51735 3 254 1.3E-72 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1007000 8be971ac3c65ea9d594863533ee7a896 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.7E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 303 9.7E-38 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 Gene3D G3DSA:3.30.70.250 124 198 8.7E-101 T 13-10-2018 MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 SUPERFAMILY SSF55048 128 198 4.32E-15 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 SUPERFAMILY SSF52151 4 307 4.71E-79 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 Pfam PF00698 Acyl transferase domain 7 283 2.6E-35 T 13-10-2018 IPR014043 Acyl transferase MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 Gene3D G3DSA:3.40.366.10 7 285 8.7E-101 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 PIRSF PIRSF000446 1 309 1.0E-123 T 13-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MADE_1008695 7e2eace6af19cd21006be2a69bb382ee 309 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 5.5E-116 T 13-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.4E-28 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 1.4E-28 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 PRINTS PR00702 Acriflavin resistance protein family signature 623 637 1.4E-28 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.4E-28 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.4E-28 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 1.4E-28 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.4E-28 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:3.30.2090.10 189 280 3.4E-283 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 SUPERFAMILY SSF82693 42 127 2.62E-20 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:3.30.70.1430 42 821 3.4E-283 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:3.30.70.1430 570 674 3.4E-283 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:3.30.2090.10 726 813 3.4E-283 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 SUPERFAMILY SSF82693 575 667 2.77E-6 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 SUPERFAMILY SSF82866 299 506 2.62E-33 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:3.30.70.1440 675 871 3.4E-283 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 SUPERFAMILY SSF82714 192 274 2.22E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 SUPERFAMILY SSF82714 725 809 7.85E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:1.20.1640.10 519 1026 3.4E-283 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:1.20.1640.10 15 518 3.4E-283 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 SUPERFAMILY SSF82866 808 1033 2.62E-52 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Gene3D G3DSA:3.30.70.1320 135 333 3.4E-283 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 SUPERFAMILY SSF82693 155 333 5.58E-17 T 13-10-2018 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 Pfam PF00873 AcrB/AcrD/AcrF family 5 1029 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001815 fbfb73c3197c499415b87e45aa32f09d 1035 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1034 0.0 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MADE_1012925 92124aa29f176fc79ca370e66bdca460 274 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MADE_1012925 92124aa29f176fc79ca370e66bdca460 274 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 6.8E-78 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MADE_1012925 92124aa29f176fc79ca370e66bdca460 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 3.8E-5 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1012925 92124aa29f176fc79ca370e66bdca460 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 119 150 4.9E-6 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1012925 92124aa29f176fc79ca370e66bdca460 274 Gene3D G3DSA:2.160.10.10 67 190 3.6E-34 T 13-10-2018 MADE_1012925 92124aa29f176fc79ca370e66bdca460 274 Gene3D G3DSA:1.10.3130.10 1 66 1.7E-22 T 13-10-2018 MADE_1012925 92124aa29f176fc79ca370e66bdca460 274 SUPERFAMILY SSF51161 3 168 1.21E-53 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1019565 80cbe23c53a51ea6db8240189ecfd01a 93 Gene3D G3DSA:3.10.50.40 2 92 8.1E-37 T 13-10-2018 MADE_1019565 80cbe23c53a51ea6db8240189ecfd01a 93 SUPERFAMILY SSF54534 5 87 3.73E-28 T 13-10-2018 MADE_1019565 80cbe23c53a51ea6db8240189ecfd01a 93 Pfam PF13616 PPIC-type PPIASE domain 13 89 3.4E-22 T 13-10-2018 MADE_1019565 80cbe23c53a51ea6db8240189ecfd01a 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SUPERFAMILY SSF55073 972 1128 1.59E-45 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Pfam PF13426 PAS domain 853 955 2.1E-8 T 13-10-2018 IPR000014 PAS domain MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Gene3D G3DSA:3.20.20.450 1141 1389 2.7E-73 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Gene3D G3DSA:2.130.10.10 471 678 7.0E-29 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SUPERFAMILY SSF63829 268 464 5.69E-6 T 13-10-2018 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 965 1120 7.2E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Gene3D G3DSA:2.130.10.10 25 351 8.7E-37 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SMART SM00052 1138 1382 4.8E-73 T 13-10-2018 IPR001633 EAL domain MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 839 963 2.5E-10 T 13-10-2018 IPR000014 PAS domain MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Pfam PF00563 EAL domain 1144 1377 8.0E-56 T 13-10-2018 IPR001633 EAL domain MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SUPERFAMILY SSF141868 1143 1389 3.4E-71 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SUPERFAMILY SSF63829 476 676 8.83E-9 T 13-10-2018 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Pfam PF00990 Diguanylate cyclase, GGDEF domain 967 1120 4.5E-47 T 13-10-2018 IPR000160 GGDEF domain MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Gene3D G3DSA:3.30.450.20 835 960 9.4E-17 T 13-10-2018 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SMART SM00267 956 1127 2.1E-56 T 13-10-2018 IPR000160 GGDEF domain MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Gene3D G3DSA:2.60.40.10 688 799 4.0E-10 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 Gene3D G3DSA:3.30.70.270 961 1140 6.9E-57 T 13-10-2018 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SUPERFAMILY SSF63829 28 168 3.92E-8 T 13-10-2018 MADE_1013655 da01c966ec8a2dd1c790e281b7192c95 1392 SUPERFAMILY SSF55785 852 963 3.32E-13 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1012460 aea4c64ef1d1559601ca6545a62ca967 418 PIRSF PIRSF000412 1 418 2.0E-169 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MADE_1012460 aea4c64ef1d1559601ca6545a62ca967 418 Gene3D G3DSA:3.90.1150.10 10 395 1.2E-186 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1012460 aea4c64ef1d1559601ca6545a62ca967 418 Gene3D G3DSA:3.40.640.10 37 290 1.2E-186 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1012460 aea4c64ef1d1559601ca6545a62ca967 418 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 418 52.989 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MADE_1012460 aea4c64ef1d1559601ca6545a62ca967 418 SUPERFAMILY SSF53383 6 417 2.72E-182 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1012460 aea4c64ef1d1559601ca6545a62ca967 418 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 13-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MADE_1012460 aea4c64ef1d1559601ca6545a62ca967 418 Pfam PF00464 Serine hydroxymethyltransferase 9 387 5.8E-185 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 Gene3D G3DSA:3.30.565.10 736 897 2.6E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014330 5827ae809fe56f89586802528d07283d 1121 SUPERFAMILY SSF47384 656 738 1.65E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 784 893 1.6E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014330 5827ae809fe56f89586802528d07283d 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 838 848 2.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 879 892 2.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 855 873 2.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 PRINTS PR00344 Bacterial sensor protein C-terminal signature 820 834 2.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 Pfam PF00512 His Kinase A (phospho-acceptor) domain 671 737 1.9E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 SMART SM00387 784 895 2.7E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014330 5827ae809fe56f89586802528d07283d 1121 SMART SM00388 671 737 1.6E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 Gene3D G3DSA:1.10.287.130 636 735 5.5E-24 T 13-10-2018 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 Gene3D G3DSA:3.40.50.2300 910 1050 5.0E-22 T 13-10-2018 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 Pfam PF00072 Response regulator receiver domain 920 1029 1.5E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 Gene3D G3DSA:1.10.4160.10 21 487 2.0E-18 T 13-10-2018 IPR038271 Purine-cytosine permease superfamily MADE_1014330 5827ae809fe56f89586802528d07283d 1121 SMART SM00448 918 1029 5.5E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014330 5827ae809fe56f89586802528d07283d 1121 SUPERFAMILY SSF52172 917 1058 6.97E-24 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014330 5827ae809fe56f89586802528d07283d 1121 SUPERFAMILY SSF55874 727 891 2.36E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Pfam PF00204 DNA gyrase B 222 392 1.5E-60 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 SUPERFAMILY SSF56719 396 796 6.28E-87 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Gene3D G3DSA:3.40.50.670 688 805 6.6E-26 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 ProSitePatterns PS00177 DNA topoisomerase II signature. 424 432 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 SMART SM00433 37 799 2.5E-272 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Gene3D G3DSA:3.30.230.10 222 394 2.9E-74 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 SUPERFAMILY SSF54211 222 394 1.29E-60 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 SMART SM00387 33 177 1.0E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 7 806 0.0 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 SUPERFAMILY SSF55874 6 219 5.89E-74 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 4 806 107.653 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 489 505 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 115 129 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 270 283 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 738 754 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 422 436 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 37 52 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 507 524 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 72 85 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR00418 DNA topoisomerase II family signature 527 539 7.9E-71 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Gene3D G3DSA:3.30.565.10 3 221 1.7E-94 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Pfam PF01751 Toprim domain 421 533 6.7E-19 T 13-10-2018 IPR006171 TOPRIM domain MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Gene3D G3DSA:3.10.20.690 598 685 5.0E-21 T 13-10-2018 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 174 2.0E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 244 262 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 314 330 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 362 376 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 197 210 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 221 243 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 182 197 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 759 771 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 7 17 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 472 481 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 775 791 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 PRINTS PR01159 DNA gyrase subunit B signature 376 396 4.3E-85 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Gene3D G3DSA:3.40.50.670 400 597 1.7E-74 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1000025 58cae61c4ac22331ce9cb9ddb54ac079 806 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 736 795 4.4E-30 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 MADE_1001420 ef752aaea1ad5817351ff3885a5bd025 249 Pfam PF01936 NYN domain 9 142 6.1E-32 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type MADE_1001420 ef752aaea1ad5817351ff3885a5bd025 249 Pfam PF12872 OST-HTH/LOTUS domain 172 235 1.4E-12 T 13-10-2018 IPR025605 OST-HTH/LOTUS domain MADE_1001420 ef752aaea1ad5817351ff3885a5bd025 249 Gene3D G3DSA:3.40.50.1010 2 146 4.3E-17 T 13-10-2018 MADE_1001420 ef752aaea1ad5817351ff3885a5bd025 249 Gene3D G3DSA:1.10.10.1880 174 244 4.0E-19 T 13-10-2018 MADE_1011805 571df3300e5a1553974e145e574d140d 639 Pfam PF17201 Cache 3/Cache 2 fusion domain 30 247 3.8E-43 T 13-10-2018 IPR033462 Cache 3/Cache 2 fusion domain MADE_1011805 571df3300e5a1553974e145e574d140d 639 SUPERFAMILY SSF58104 330 637 4.58E-65 T 13-10-2018 MADE_1011805 571df3300e5a1553974e145e574d140d 639 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 504 533 3.5E-6 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1011805 571df3300e5a1553974e145e574d140d 639 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 391 420 3.5E-6 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1011805 571df3300e5a1553974e145e574d140d 639 SUPERFAMILY SSF103190 104 202 1.88E-10 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily MADE_1011805 571df3300e5a1553974e145e574d140d 639 Gene3D G3DSA:1.10.287.950 309 639 5.7E-63 T 13-10-2018 MADE_1011805 571df3300e5a1553974e145e574d140d 639 SMART SM00283 377 638 5.6E-52 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1011805 571df3300e5a1553974e145e574d140d 639 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 445 605 6.9E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1011805 571df3300e5a1553974e145e574d140d 639 SMART SM00304 308 362 7.3E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 Pfam PF06689 ClpX C4-type zinc finger 14 51 2.1E-20 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 SUPERFAMILY SSF57716 14 49 7.27E-12 T 13-10-2018 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 SUPERFAMILY SSF52540 63 404 2.83E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 SMART SM00382 112 355 4.3E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 395 2.0E-15 T 13-10-2018 IPR019489 Clp ATPase, C-terminal MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 Gene3D G3DSA:3.40.50.300 63 316 1.0E-109 T 13-10-2018 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 SMART SM00994 13 52 1.8E-24 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 Gene3D G3DSA:1.10.8.60 317 424 4.8E-40 T 13-10-2018 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 416 53.227 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 Gene3D G3DSA:3.30.50.30 3 53 1.1E-25 T 13-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 311 7.7E-50 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 SMART SM01086 318 413 1.1E-32 T 13-10-2018 IPR019489 Clp ATPase, C-terminal MADE_1012750 76a24553b1c4535c5e814ad25d2154dc 424 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 413 1.6E-210 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 MADE_000001020915 c6fe4fbb23621976da6b52aa97633541 452 PIRSF PIRSF037714 1 452 2.7E-176 T 13-10-2018 IPR017270 Putative MotA/TolQ/ExbB family protein MADE_000001020915 c6fe4fbb23621976da6b52aa97633541 452 Pfam PF01618 MotA/TolQ/ExbB proton channel family 317 435 3.8E-28 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 SUPERFAMILY SSF54506 3 276 4.32E-54 T 13-10-2018 MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 Pfam PF01678 Diaminopimelate epimerase 5 125 5.1E-36 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 Pfam PF01678 Diaminopimelate epimerase 154 269 1.3E-29 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 38.537 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 Gene3D G3DSA:3.10.310.10 5 272 3.2E-104 T 13-10-2018 MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 Gene3D G3DSA:3.10.310.10 117 263 3.2E-104 T 13-10-2018 MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 274 5.2E-99 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MADE_1001010 bff8eb5d50303964e573e1e6761dddef 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 13-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 SUPERFAMILY SSF100950 13 217 3.86E-37 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 Gene3D G3DSA:3.30.750.70 181 284 5.6E-42 T 13-10-2018 MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 Gene3D G3DSA:3.40.1080.10 4 179 2.2E-58 T 13-10-2018 MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 13 180 6.6E-19 T 13-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 Gene3D G3DSA:3.40.1080.20 285 433 5.2E-62 T 13-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 SUPERFAMILY SSF100950 183 434 2.43E-68 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 267 419 5.8E-65 T 13-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 SUPERFAMILY SSF55729 402 594 4.51E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 Pfam PF00583 Acetyltransferase (GNAT) family 509 590 2.9E-7 T 13-10-2018 IPR000182 GNAT domain MADE_1000910 b33451b4be1041558e7475ca8bebddd5 613 Gene3D G3DSA:3.40.630.30 449 612 2.4E-26 T 13-10-2018 MADE_000001021280 e817a4885ddfe5c65bfe6d6e24ce66c1 188 SUPERFAMILY SSF81342 5 183 2.28E-31 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MADE_000001021280 e817a4885ddfe5c65bfe6d6e24ce66c1 188 Pfam PF01292 Prokaryotic cytochrome b561 9 183 5.0E-26 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MADE_1014075 df86cab8abf4b55051ec9445cbf9a31a 130 SUPERFAMILY SSF46785 9 127 1.42E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1014075 df86cab8abf4b55051ec9445cbf9a31a 130 Gene3D G3DSA:1.10.10.10 9 75 4.4E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1014075 df86cab8abf4b55051ec9445cbf9a31a 130 PIRSF PIRSF019455 2 130 7.8E-41 T 13-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MADE_1014075 df86cab8abf4b55051ec9445cbf9a31a 130 Gene3D G3DSA:1.10.4040.10 76 127 6.6E-13 T 13-10-2018 MADE_1014075 df86cab8abf4b55051ec9445cbf9a31a 130 Pfam PF03965 Penicillinase repressor 10 123 3.3E-35 T 13-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 SMART SM00267 273 442 5.3E-24 T 13-10-2018 IPR000160 GGDEF domain MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 SUPERFAMILY SSF141868 457 703 2.22E-86 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 SMART SM00052 452 697 1.0E-102 T 13-10-2018 IPR001633 EAL domain MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 Gene3D G3DSA:3.20.20.450 455 705 2.9E-94 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 SUPERFAMILY SSF55073 288 444 4.08E-30 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 SUPERFAMILY SSF55785 173 277 4.61E-7 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 Gene3D G3DSA:3.30.70.270 281 454 2.4E-35 T 13-10-2018 MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 Pfam PF00990 Diguanylate cyclase, GGDEF domain 285 438 4.4E-27 T 13-10-2018 IPR000160 GGDEF domain MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 Gene3D G3DSA:3.30.450.20 157 274 1.2E-6 T 13-10-2018 MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 284 439 3.5E-22 T 13-10-2018 IPR000160 GGDEF domain MADE_1016940 ee0a98ecaf03f6a0637bba2c2c84dee9 706 Pfam PF00563 EAL domain 458 692 1.2E-71 T 13-10-2018 IPR001633 EAL domain MADE_1015390 5d0e848b0934ae69cc1436f6f402d682 181 SUPERFAMILY SSF49329 35 180 6.15E-49 T 13-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MADE_1015390 5d0e848b0934ae69cc1436f6f402d682 181 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 168 179 - T 13-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MADE_1015390 5d0e848b0934ae69cc1436f6f402d682 181 Gene3D G3DSA:2.60.40.200 23 181 1.5E-48 T 13-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MADE_1015390 5d0e848b0934ae69cc1436f6f402d682 181 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 72 82 - T 13-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MADE_1015390 5d0e848b0934ae69cc1436f6f402d682 181 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 41 179 7.4E-35 T 13-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 SUPERFAMILY SSF53901 213 402 4.94E-59 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 Gene3D G3DSA:3.40.47.10 1 253 8.4E-63 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 SMART SM00825 Beta-ketoacyl synthase 4 404 2.8E-11 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 SUPERFAMILY SSF53901 1 251 2.08E-60 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 244 7.3E-40 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 359 3.5E-29 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MADE_1011950 ecc4bf56ec89f29ad0f6a4d913459b28 404 Gene3D G3DSA:3.40.47.10 258 402 1.5E-46 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 459 3.1E-84 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 Pfam PF01336 OB-fold nucleic acid binding domain 20 99 3.4E-11 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 SUPERFAMILY SSF50249 15 100 3.64E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 Gene3D G3DSA:3.30.930.10 101 464 7.2E-111 T 13-10-2018 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 SUPERFAMILY SSF55681 95 463 3.83E-98 T 13-10-2018 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 Gene3D G3DSA:2.40.50.140 1 100 1.8E-20 T 13-10-2018 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 465 45.64 T 13-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 465 4.0E-199 T 13-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 219 6.6E-14 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 223 236 6.6E-14 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 380 396 6.6E-14 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001021380 25bedfa895f8e28ca9a7b4e0026d9425 465 PRINTS PR01042 Aspartyl-tRNA synthetase signature 420 434 6.6E-14 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SMART SM00086 245 286 0.043 T 13-10-2018 IPR001610 PAC motif MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SMART SM00086 126 170 0.31 T 13-10-2018 IPR001610 PAC motif MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 Gene3D G3DSA:3.30.450.20 186 294 3.5E-13 T 13-10-2018 MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 Gene3D G3DSA:3.20.20.450 463 717 1.1E-72 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SMART SM00091 178 245 0.0015 T 13-10-2018 IPR000014 PAS domain MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 Gene3D G3DSA:3.30.70.270 295 456 4.7E-46 T 13-10-2018 MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 182 293 9.5E-9 T 13-10-2018 IPR000014 PAS domain MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SUPERFAMILY SSF141868 470 714 1.57E-69 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 Gene3D G3DSA:3.30.450.20 64 176 2.0E-10 T 13-10-2018 MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SMART SM00267 286 454 9.2E-44 T 13-10-2018 IPR000160 GGDEF domain MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SUPERFAMILY SSF55785 189 295 7.09E-13 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 Pfam PF13426 PAS domain 189 285 2.9E-6 T 13-10-2018 IPR000014 PAS domain MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 Pfam PF00990 Diguanylate cyclase, GGDEF domain 297 449 5.1E-36 T 13-10-2018 IPR000160 GGDEF domain MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SMART SM00052 464 709 9.6E-72 T 13-10-2018 IPR001633 EAL domain MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SUPERFAMILY SSF55073 302 456 7.69E-40 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 Pfam PF00563 EAL domain 470 704 8.8E-60 T 13-10-2018 IPR001633 EAL domain MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 SUPERFAMILY SSF55785 100 173 4.54E-7 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1002490 46d719d24b7afcf1dc532d91777a0e8c 720 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 294 452 1.4E-37 T 13-10-2018 IPR000160 GGDEF domain MADE_1000305 8cabbe5a375201d18d1957bc912617d8 391 SUPERFAMILY SSF56935 16 391 1.62E-17 T 13-10-2018 MADE_1002060 1a2e8a3dc56e674f35532e262ee3d680 172 SUPERFAMILY SSF56784 9 172 7.89E-29 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1002060 1a2e8a3dc56e674f35532e262ee3d680 172 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 171 1.9E-18 T 13-10-2018 MADE_1002060 1a2e8a3dc56e674f35532e262ee3d680 172 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 14 171 2.6E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002060 1a2e8a3dc56e674f35532e262ee3d680 172 Gene3D G3DSA:1.10.260.80 24 75 1.3E-49 T 13-10-2018 MADE_1002060 1a2e8a3dc56e674f35532e262ee3d680 172 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 90 166 1.7E-9 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002060 1a2e8a3dc56e674f35532e262ee3d680 172 Gene3D G3DSA:3.40.50.1000 12 171 1.3E-49 T 13-10-2018 IPR023214 HAD superfamily MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 277 1.7E-91 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 6.0E-41 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 Pfam PF00303 Thymidylate synthase 2 277 3.0E-121 T 13-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 Hamap MF_00008 Thymidylate synthase [thyA]. 1 277 41.423 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 Gene3D G3DSA:3.30.572.10 1 277 8.6E-128 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.5E-41 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 PRINTS PR00108 Thymidylate synthase family signature 115 134 2.5E-41 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 PRINTS PR00108 Thymidylate synthase family signature 172 198 2.5E-41 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 PRINTS PR00108 Thymidylate synthase family signature 210 227 2.5E-41 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1003460 65f5b61d0cc8ad60fd90d54a63c73e3b 277 SUPERFAMILY SSF55831 1 277 4.45E-126 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 SUPERFAMILY SSF56645 10 253 2.49E-78 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 Gene3D G3DSA:1.20.140.10 245 396 1.0E-54 T 13-10-2018 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 Gene3D G3DSA:1.10.540.10 2 132 8.9E-36 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 129 1.1E-27 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 PIRSF PIRSF016578 221 396 2.3E-12 T 13-10-2018 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 PIRSF PIRSF016578 12 205 4.2E-12 T 13-10-2018 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 136 148 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 SUPERFAMILY SSF47203 238 392 2.58E-60 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 390 9.5E-48 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 Gene3D G3DSA:2.40.110.10 133 244 3.1E-41 T 13-10-2018 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 348 367 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MADE_1009645 9f2091e6e6d14f4caac7de32009fb5b1 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 228 1.6E-25 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 Pfam PF03466 LysR substrate binding domain 101 293 1.3E-15 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 Gene3D G3DSA:3.40.190.10 90 290 8.5E-55 T 13-10-2018 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 SUPERFAMILY SSF53850 90 294 7.29E-44 T 13-10-2018 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.3E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 Gene3D G3DSA:1.10.10.10 1 89 1.8E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 Gene3D G3DSA:3.40.190.10 171 265 8.5E-55 T 13-10-2018 MADE_1008870 f0d02ddc97bf7a3f3a9d6b6f36d91840 300 SUPERFAMILY SSF46785 2 85 9.8E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1002875 4d4ab15b22543800c2c42abb94a011bf 424 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 24 398 1.1E-137 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MADE_1002875 4d4ab15b22543800c2c42abb94a011bf 424 Gene3D G3DSA:1.20.1530.10 19 405 5.9E-148 T 13-10-2018 IPR023171 Na/H antiporter domain superfamily MADE_1002875 4d4ab15b22543800c2c42abb94a011bf 424 Pfam PF06965 Na+/H+ antiporter 1 23 398 1.0E-147 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MADE_1002875 4d4ab15b22543800c2c42abb94a011bf 424 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 21 404 22.815 T 13-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 SMART SM00354 7 80 1.3E-18 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 Gene3D G3DSA:1.10.260.40 4 65 5.0E-21 T 13-10-2018 MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 52 7.0E-17 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 Pfam PF13377 Periplasmic binding protein-like domain 181 340 5.0E-38 T 13-10-2018 MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 SUPERFAMILY SSF47413 7 65 3.64E-17 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 Gene3D G3DSA:3.40.50.2300 84 332 2.1E-62 T 13-10-2018 MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 SUPERFAMILY SSF53822 64 326 1.14E-53 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1009575 ea79ae44da1f35bc0e72192e6d6a7af4 343 Gene3D G3DSA:3.40.50.2300 172 338 2.1E-62 T 13-10-2018 MADE_1006065 21a68556bd810045aa54ba06cfa8678e 217 Pfam PF00484 Carbonic anhydrase 35 191 2.8E-50 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MADE_1006065 21a68556bd810045aa54ba06cfa8678e 217 SMART SM00947 27 195 2.6E-66 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MADE_1006065 21a68556bd810045aa54ba06cfa8678e 217 Gene3D G3DSA:3.40.1050.10 1 204 1.1E-71 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MADE_1006065 21a68556bd810045aa54ba06cfa8678e 217 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MADE_1006065 21a68556bd810045aa54ba06cfa8678e 217 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 39 46 - T 13-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 MADE_1006065 21a68556bd810045aa54ba06cfa8678e 217 SUPERFAMILY SSF53056 1 210 3.66E-66 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 Pfam PF13715 CarboxypepD_reg-like domain 34 103 1.0E-9 T 13-10-2018 MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 114 899 1.0E-168 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 Pfam PF00593 TonB dependent receptor 404 898 6.1E-41 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 Gene3D G3DSA:2.60.40.1120 33 108 2.9E-7 T 13-10-2018 MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 Gene3D G3DSA:2.170.130.10 111 242 7.4E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 SUPERFAMILY SSF56935 115 899 6.51E-103 T 13-10-2018 MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 Pfam PF07715 TonB-dependent Receptor Plug Domain 136 237 3.9E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 Gene3D G3DSA:2.40.170.20 265 900 2.3E-54 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1008515 909ad753ad53291384aabc9ecaaec686 901 SUPERFAMILY SSF49452 29 106 4.9E-10 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 MADE_1019665 182d562932b616fc49f746513ccbd528 447 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 1.3E-236 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 MADE_1019665 182d562932b616fc49f746513ccbd528 447 Gene3D G3DSA:3.30.470.20 87 432 2.8E-155 T 13-10-2018 MADE_1019665 182d562932b616fc49f746513ccbd528 447 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1019665 182d562932b616fc49f746513ccbd528 447 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 5.8E-37 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1019665 182d562932b616fc49f746513ccbd528 447 SUPERFAMILY SSF51246 331 444 2.09E-43 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MADE_1019665 182d562932b616fc49f746513ccbd528 447 SUPERFAMILY SSF56059 83 346 1.94E-70 T 13-10-2018 MADE_1019665 182d562932b616fc49f746513ccbd528 447 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1019665 182d562932b616fc49f746513ccbd528 447 SMART SM00878 336 441 4.5E-63 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1019665 182d562932b616fc49f746513ccbd528 447 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.7E-44 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1019665 182d562932b616fc49f746513ccbd528 447 SUPERFAMILY SSF52440 1 113 1.29E-45 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1019665 182d562932b616fc49f746513ccbd528 447 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 6.5E-85 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1019665 182d562932b616fc49f746513ccbd528 447 Gene3D G3DSA:3.30.1490.20 131 203 2.8E-155 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1019665 182d562932b616fc49f746513ccbd528 447 Gene3D G3DSA:3.40.50.20 1 85 1.8E-34 T 13-10-2018 MADE_1020065 a0e9a0583318415b1271bc477de567ae 305 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 19 300 19.613 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MADE_1020065 a0e9a0583318415b1271bc477de567ae 305 Gene3D G3DSA:1.10.357.140 26 185 2.9E-20 T 13-10-2018 MADE_1020065 a0e9a0583318415b1271bc477de567ae 305 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 21 299 9.4E-100 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MADE_1020065 a0e9a0583318415b1271bc477de567ae 305 Pfam PF01040 UbiA prenyltransferase family 35 283 9.1E-61 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MADE_1020065 a0e9a0583318415b1271bc477de567ae 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 74 96 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site MADE_1015830 ff4f38fba731c4c08d2e89eb5eb0ab74 199 Pfam PF00583 Acetyltransferase (GNAT) family 51 157 2.0E-5 T 13-10-2018 IPR000182 GNAT domain MADE_1015830 ff4f38fba731c4c08d2e89eb5eb0ab74 199 SUPERFAMILY SSF55729 16 168 4.43E-15 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1015830 ff4f38fba731c4c08d2e89eb5eb0ab74 199 Gene3D G3DSA:3.40.630.30 18 176 1.8E-11 T 13-10-2018 MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 Gene3D G3DSA:1.20.120.530 71 219 7.3E-30 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 SMART SM00895 83 208 5.6E-23 T 13-10-2018 IPR011711 GntR, C-terminal MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 SUPERFAMILY SSF46785 9 102 8.51E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 SUPERFAMILY SSF48008 80 214 5.49E-28 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 Pfam PF07729 FCD domain 83 206 1.0E-24 T 13-10-2018 IPR011711 GntR, C-terminal MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 SMART SM00345 15 73 1.3E-14 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 Gene3D G3DSA:1.10.10.10 4 70 1.4E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015690 0022fdb9cb5eb354598974cc4e769faf 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 73 1.7E-16 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1012655 a221d44370213080fb456b771a1749b5 182 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 7 162 18.08 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MADE_1012655 a221d44370213080fb456b771a1749b5 182 TIGRFAM TIGR00077 lspA: signal peptidase II 4 163 5.1E-48 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MADE_1012655 a221d44370213080fb456b771a1749b5 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 101 116 4.2E-18 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MADE_1012655 a221d44370213080fb456b771a1749b5 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 53 61 4.2E-18 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MADE_1012655 a221d44370213080fb456b771a1749b5 182 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 137 153 4.2E-18 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MADE_1012655 a221d44370213080fb456b771a1749b5 182 Pfam PF01252 Signal peptidase (SPase) II 16 156 5.9E-43 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MADE_1012655 a221d44370213080fb456b771a1749b5 182 ProSitePatterns PS00855 Signal peptidases II signature. 104 116 - T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 MADE_1006750 5876a9b60f6f2de36188c1931dc8d77e 653 Pfam PF00990 Diguanylate cyclase, GGDEF domain 494 646 7.7E-35 T 13-10-2018 IPR000160 GGDEF domain MADE_1006750 5876a9b60f6f2de36188c1931dc8d77e 653 SUPERFAMILY SSF55073 499 651 1.33E-35 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1006750 5876a9b60f6f2de36188c1931dc8d77e 653 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 493 650 4.7E-37 T 13-10-2018 IPR000160 GGDEF domain MADE_1006750 5876a9b60f6f2de36188c1931dc8d77e 653 Gene3D G3DSA:1.25.40.10 183 424 2.0E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006750 5876a9b60f6f2de36188c1931dc8d77e 653 SMART SM00267 484 651 2.7E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_1006750 5876a9b60f6f2de36188c1931dc8d77e 653 Gene3D G3DSA:3.30.70.270 492 653 1.7E-42 T 13-10-2018 MADE_1005975 4d5e2a8ff8604a92df2d25714421e903 477 Pfam PF00448 SRP54-type protein, GTPase domain 268 455 3.1E-42 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_1005975 4d5e2a8ff8604a92df2d25714421e903 477 SMART SM00962 265 458 2.2E-58 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_1005975 4d5e2a8ff8604a92df2d25714421e903 477 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 353 1.1E-79 T 13-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 MADE_1005975 4d5e2a8ff8604a92df2d25714421e903 477 Gene3D G3DSA:3.40.50.300 261 446 3.9E-58 T 13-10-2018 MADE_1005975 4d5e2a8ff8604a92df2d25714421e903 477 SMART SM00382 264 402 8.3E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005975 4d5e2a8ff8604a92df2d25714421e903 477 SUPERFAMILY SSF52540 267 455 4.2E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1005975 4d5e2a8ff8604a92df2d25714421e903 477 Gene3D G3DSA:1.20.120.1380 245 449 3.9E-58 T 13-10-2018 MADE_1012710 88fc43a8c8868bac107ed2b867873923 265 Gene3D G3DSA:3.60.21.10 6 250 3.6E-21 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like MADE_1012710 88fc43a8c8868bac107ed2b867873923 265 SUPERFAMILY SSF56300 5 229 4.91E-30 T 13-10-2018 MADE_1012710 88fc43a8c8868bac107ed2b867873923 265 Pfam PF00149 Calcineurin-like phosphoesterase 7 207 2.2E-11 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 Gene3D G3DSA:1.10.287.130 141 216 1.9E-13 T 13-10-2018 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 Gene3D G3DSA:3.30.450.20 39 140 1.4E-6 T 13-10-2018 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 Gene3D G3DSA:3.30.565.10 220 378 2.0E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1005885 c90879d51a113856932e3c3a1f218609 380 SUPERFAMILY SSF47384 143 218 7.46E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 SUPERFAMILY SSF55785 48 131 9.52E-9 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1005885 c90879d51a113856932e3c3a1f218609 380 SUPERFAMILY SSF55874 208 366 6.81E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1005885 c90879d51a113856932e3c3a1f218609 380 Pfam PF13188 PAS domain 47 101 4.7E-6 T 13-10-2018 IPR000014 PAS domain MADE_1005885 c90879d51a113856932e3c3a1f218609 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 266 365 6.6E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1005885 c90879d51a113856932e3c3a1f218609 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 346 5.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 313 5.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 365 5.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 327 5.6E-19 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 SMART SM00388 153 219 1.4E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 153 218 3.9E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1005885 c90879d51a113856932e3c3a1f218609 380 SMART SM00387 262 368 3.7E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 184 200 2.1E-12 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 200 215 2.1E-12 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 Gene3D G3DSA:2.60.120.10 34 155 1.3E-42 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 Pfam PF00027 Cyclic nucleotide-binding domain 42 126 8.1E-15 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 SMART SM00419 178 226 2.3E-13 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 Gene3D G3DSA:1.10.10.10 156 235 8.6E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 SUPERFAMILY SSF51206 14 152 1.57E-27 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 SUPERFAMILY SSF46785 157 232 2.38E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 ProSitePatterns PS00042 Crp-type HTH domain signature. 186 209 - T 13-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 SMART SM00100 21 142 7.5E-14 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain MADE_1010460 1bb258aae3bec3ba40b4ec5b4a3b6130 246 Pfam PF13545 Crp-like helix-turn-helix domain 159 231 5.2E-16 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 Gene3D G3DSA:4.10.640.10 20 75 6.2E-29 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 4.2E-37 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.1E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.1E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.1E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.1E-18 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 13-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.505 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 72 1.0E-21 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 Pfam PF01084 Ribosomal protein S18 19 68 1.0E-25 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018945 f5e5489255dc0c3d92845d51db0f0d98 75 SUPERFAMILY SSF46911 3 74 5.23E-29 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 SUPERFAMILY SSF46894 30 93 2.58E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 38 52 1.2E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 68 80 1.2E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 52 68 1.2E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 Gene3D G3DSA:1.10.10.10 28 101 5.3E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 Pfam PF00196 Bacterial regulatory proteins, luxR family 38 89 7.5E-21 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 ProSitePatterns PS00622 LuxR-type HTH domain signature. 52 79 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1018260 d77b373474bcbf848fca94a5ff961363 103 SMART SM00421 35 92 1.4E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 Gene3D G3DSA:3.30.700.10 23 138 1.4E-34 T 13-10-2018 MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 8 139 2.9E-49 T 13-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 29 2.4E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 SUPERFAMILY SSF54523 35 140 7.32E-37 T 13-10-2018 MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 1.9E-17 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 1.9E-17 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 5.7E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019840 e4ca168884c99e3444ecb9edfe91603e 145 Pfam PF08334 Type II secretion system (T2SS), protein G 32 138 3.0E-35 T 13-10-2018 IPR013545 Type II secretion system protein G MADE_1015930 6293c6f166a31c2b2097d25f0fb741c8 149 Gene3D G3DSA:2.60.40.420 21 149 2.4E-41 T 13-10-2018 IPR008972 Cupredoxin MADE_1015930 6293c6f166a31c2b2097d25f0fb741c8 149 SUPERFAMILY SSF49503 22 147 1.5E-44 T 13-10-2018 IPR008972 Cupredoxin MADE_1015930 6293c6f166a31c2b2097d25f0fb741c8 149 TIGRFAM TIGR02695 azurin: azurin 23 147 1.1E-59 T 13-10-2018 IPR014068 Azurin MADE_1015930 6293c6f166a31c2b2097d25f0fb741c8 149 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 25 147 2.0E-34 T 13-10-2018 MADE_1015930 6293c6f166a31c2b2097d25f0fb741c8 149 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 22 148 5.8E-27 T 13-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 MADE_1015120 6c0169df969ded9e242e7a82949f3f91 303 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 298 3.1E-126 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MADE_1015120 6c0169df969ded9e242e7a82949f3f91 303 SUPERFAMILY SSF54211 134 278 7.59E-51 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1015120 6c0169df969ded9e242e7a82949f3f91 303 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 276 8.8E-107 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MADE_1015120 6c0169df969ded9e242e7a82949f3f91 303 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 280 45.21 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MADE_1015120 6c0169df969ded9e242e7a82949f3f91 303 SUPERFAMILY SSF54211 3 126 1.29E-41 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1015120 6c0169df969ded9e242e7a82949f3f91 303 Gene3D G3DSA:3.30.1700.10 129 303 1.5E-65 T 13-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MADE_1015120 6c0169df969ded9e242e7a82949f3f91 303 Gene3D G3DSA:3.30.230.20 1 128 7.7E-52 T 13-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 SUPERFAMILY SSF55874 812 973 3.54E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 866 974 8.4E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 Pfam PF12860 PAS fold 613 721 2.3E-36 T 13-10-2018 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 Gene3D G3DSA:1.10.287.130 723 819 1.4E-12 T 13-10-2018 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 SUPERFAMILY SSF47384 742 821 4.71E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 938 956 5.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 962 975 5.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 924 934 5.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 PRINTS PR00344 Bacterial sensor protein C-terminal signature 906 920 5.2E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 Pfam PF00474 Sodium:solute symporter family 47 442 9.3E-10 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 Gene3D G3DSA:3.30.450.20 594 722 6.1E-9 T 13-10-2018 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 Gene3D G3DSA:3.30.565.10 821 977 7.9E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 SMART SM00387 865 978 1.3E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 Gene3D G3DSA:1.20.1730.10 42 527 1.9E-12 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 SMART SM00388 756 821 2.9E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1007045 61c87ca053bf6adc7cc9c1bf312f62fa 1006 SUPERFAMILY SSF55785 619 726 1.79E-5 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1013025 d2c4b3a9d4303f12d7f5a7fabd44aa09 230 SMART SM00382 28 225 1.8E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1013025 d2c4b3a9d4303f12d7f5a7fabd44aa09 230 Gene3D G3DSA:3.40.50.300 1 228 2.1E-54 T 13-10-2018 MADE_1013025 d2c4b3a9d4303f12d7f5a7fabd44aa09 230 Pfam PF00005 ABC transporter 19 166 2.0E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1013025 d2c4b3a9d4303f12d7f5a7fabd44aa09 230 SUPERFAMILY SSF52540 1 219 2.11E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1005670 2d8dada950c708929a4fe2cede333be8 394 Gene3D G3DSA:2.40.10.410 309 394 8.2E-12 T 13-10-2018 IPR038165 FlgT, C-terminal domain superfamily MADE_1005670 2d8dada950c708929a4fe2cede333be8 394 Pfam PF16539 Flagellar assembly protein T, middle domain 124 273 3.8E-34 T 13-10-2018 IPR032386 Flagellar assembly protein T, middle domain MADE_1005670 2d8dada950c708929a4fe2cede333be8 394 Gene3D G3DSA:3.40.50.10610 124 308 2.7E-44 T 13-10-2018 MADE_1005670 2d8dada950c708929a4fe2cede333be8 394 Gene3D G3DSA:3.30.1660.40 33 123 1.4E-28 T 13-10-2018 IPR038180 FlgT, N-terminal domain superfamily MADE_1005670 2d8dada950c708929a4fe2cede333be8 394 Pfam PF16538 Flagellar assembly protein T, C-terminal domain 317 393 6.5E-15 T 13-10-2018 IPR032388 Flagellar assembly protein T, C-terminal MADE_1005670 2d8dada950c708929a4fe2cede333be8 394 Pfam PF16548 Flagellar assembly protein T, N-terminal domain 33 120 4.8E-24 T 13-10-2018 IPR032370 Flagellar assembly protein T, N-terminal MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 13-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 385 3.3E-135 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 PIRSF PIRSF000429 1 387 7.9E-126 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 Gene3D G3DSA:3.40.47.10 4 267 4.6E-145 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 ProSitePatterns PS00099 Thiolases active site. 368 381 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 3 387 2.5E-207 T 13-10-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 13-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 Hamap MF_01620 3-ketoacyl-CoA thiolase [fadA]. 1 387 61.823 T 13-10-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 SUPERFAMILY SSF53901 262 386 4.1E-42 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 Gene3D G3DSA:3.40.47.10 134 381 4.6E-145 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 Pfam PF02803 Thiolase, C-terminal domain 262 386 1.5E-47 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 SUPERFAMILY SSF53901 1 258 7.84E-75 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1003305 c3a4d138f77dce353f8d9a67138bfd35 387 Pfam PF00108 Thiolase, N-terminal domain 4 253 4.8E-77 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MADE_1012270 9c4aac16c0452c7e5130b7676c5f49aa 188 Pfam PF10003 Integral membrane protein (DUF2244) 43 178 1.5E-28 T 13-10-2018 IPR019253 Protein of unknown function DUF2244, transmembrane MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 Gene3D G3DSA:3.30.1360.10 16 226 2.4E-83 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 243 306 1.5E-23 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 SMART SM00662 22 232 4.1E-105 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 SUPERFAMILY SSF56553 52 176 1.57E-42 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 28 226 4.8E-23 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 23 314 5.8E-112 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 Gene3D G3DSA:1.10.150.20 242 327 2.2E-38 T 13-10-2018 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 254 326 2.0E-35 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 SUPERFAMILY SSF47789 249 324 4.19E-25 T 13-10-2018 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 4 315 34.933 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 154 6.4E-24 T 13-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 Gene3D G3DSA:2.170.120.12 52 175 2.4E-83 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1013935 712acae5045706e35f2e0a4f073ea29a 328 SUPERFAMILY SSF55257 6 231 8.34E-31 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1014930 c1bfb9536879cb5357c1fe0f5b0c3d3e 274 Gene3D G3DSA:1.10.3210.10 2 273 7.2E-46 T 13-10-2018 MADE_1014930 c1bfb9536879cb5357c1fe0f5b0c3d3e 274 SUPERFAMILY SSF109604 14 268 3.77E-44 T 13-10-2018 MADE_1014930 c1bfb9536879cb5357c1fe0f5b0c3d3e 274 Pfam PF08668 HDOD domain 15 203 6.5E-42 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD MADE_000001022370 c03e0028bcb55d5e4e2651ce4b5c05f2 967 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 158 7.1E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_000001022370 c03e0028bcb55d5e4e2651ce4b5c05f2 967 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 37 966 4.4E-148 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_000001022370 c03e0028bcb55d5e4e2651ce4b5c05f2 967 Gene3D G3DSA:2.170.130.10 44 162 1.4E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_000001022370 c03e0028bcb55d5e4e2651ce4b5c05f2 967 SUPERFAMILY SSF56935 31 966 4.58E-73 T 13-10-2018 MADE_1014460 b1a4f2729201584815b3652dd7e8300b 310 SUPERFAMILY SSF64182 4 307 8.72E-9 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily MADE_1014460 b1a4f2729201584815b3652dd7e8300b 310 Gene3D G3DSA:3.10.310.30 258 306 6.6E-6 T 13-10-2018 MADE_1014460 b1a4f2729201584815b3652dd7e8300b 310 PIRSF PIRSF028235 1 310 3.4E-161 T 13-10-2018 IPR016877 Uncharacterised conserved protein UCP028235 MADE_1000290 0b4b36ddd757cfe56d6818ca3e6f8069 244 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 35 238 5.5E-51 T 13-10-2018 MADE_1000290 0b4b36ddd757cfe56d6818ca3e6f8069 244 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 4 240 33.784 T 13-10-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 MADE_1000290 0b4b36ddd757cfe56d6818ca3e6f8069 244 Gene3D G3DSA:1.10.510.10 145 244 6.7E-16 T 13-10-2018 MADE_1000290 0b4b36ddd757cfe56d6818ca3e6f8069 244 SUPERFAMILY SSF56112 50 196 3.91E-16 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 PRINTS PR00148 Enolase signature 37 51 2.3E-45 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 PRINTS PR00148 Enolase signature 165 178 2.3E-45 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 PRINTS PR00148 Enolase signature 367 384 2.3E-45 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 PRINTS PR00148 Enolase signature 315 326 2.3E-45 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 PRINTS PR00148 Enolase signature 338 352 2.3E-45 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 PRINTS PR00148 Enolase signature 107 123 2.3E-45 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 SUPERFAMILY SSF54826 3 138 1.94E-56 T 13-10-2018 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 SMART SM01193 4 134 1.7E-91 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 Gene3D G3DSA:3.20.20.120 128 430 1.2E-136 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 ProSitePatterns PS00164 Enolase signature. 338 351 - T 13-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 7.7E-207 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 Pfam PF03952 Enolase, N-terminal domain 4 134 6.0E-59 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 428 1.6E-139 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 SUPERFAMILY SSF51604 143 426 2.4E-129 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 Gene3D G3DSA:3.30.390.10 1 127 1.5E-56 T 13-10-2018 IPR029017 Enolase-like, N-terminal MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 PIRSF PIRSF001400 1 429 1.1E-193 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 SMART SM01192 143 429 1.1E-219 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1004715 838c209cdbc8518b0c22e149d64b96ef 430 Hamap MF_00318 Enolase [eno]. 2 415 44.633 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 SUPERFAMILY SSF55120 101 317 2.08E-65 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 SUPERFAMILY SSF55174 26 77 3.3E-8 T 13-10-2018 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 Gene3D G3DSA:3.10.290.10 15 79 1.5E-15 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 SMART SM00363 27 89 6.8E-8 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 24 319 1.6E-89 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 146 160 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 Gene3D G3DSA:3.30.2350.10 99 319 2.7E-82 T 13-10-2018 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 Pfam PF00849 RNA pseudouridylate synthase 108 255 1.6E-31 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008660 94b68bf56a29153dc036cbc54fffa995 319 Pfam PF01479 S4 domain 27 73 7.5E-9 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1004225 20ebf705eb8522a3d97b35fa6855045f 258 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 8 256 1.8E-94 T 13-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria MADE_1004225 20ebf705eb8522a3d97b35fa6855045f 258 Pfam PF02405 Permease MlaE 42 253 8.4E-76 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 Pfam PF17391 Urocanase N-terminal domain 10 136 1.2E-61 T 13-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 PIRSF PIRSF001423 1 559 7.1E-290 T 13-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 Pfam PF17392 Urocanase C-terminal domain 350 544 1.6E-91 T 13-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 ProSitePatterns PS01233 Urocanase signature. 440 455 - T 13-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 Pfam PF01175 Urocanase Rossmann-like domain 139 347 4.4E-84 T 13-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 Hamap MF_00577 Urocanate hydratase [hutU]. 1 554 49.47 T 13-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 TIGRFAM TIGR01228 hutU: urocanate hydratase 8 552 2.0E-290 T 13-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 Gene3D G3DSA:3.40.1770.10 17 540 1.3E-255 T 13-10-2018 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 Gene3D G3DSA:3.40.50.10730 140 347 1.3E-255 T 13-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004505 4c8cef0e4634fdb9d7ecf634870dbbed 563 SUPERFAMILY SSF111326 3 553 1.19E-256 T 13-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Pfam PF04408 Helicase associated domain (HA2) 504 602 4.2E-15 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Pfam PF11898 Domain of unknown function (DUF3418) 750 1339 3.7E-199 T 13-10-2018 IPR024590 RNA helicase HrpA, C-terminal MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 SMART SM00382 131 423 5.8E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Gene3D G3DSA:1.20.120.1080 486 590 3.9E-15 T 13-10-2018 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 661 736 1.3E-18 T 13-10-2018 IPR011709 Domain of unknown function DUF1605 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 SMART SM00487 113 298 1.6E-28 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Gene3D G3DSA:3.40.50.300 292 457 2.2E-57 T 13-10-2018 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Pfam PF00271 Helicase conserved C-terminal domain 319 440 1.5E-12 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Gene3D G3DSA:3.40.50.300 61 291 1.0E-76 T 13-10-2018 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 SMART SM00490 341 441 6.2E-15 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 Pfam PF00270 DEAD/DEAH box helicase 127 272 1.0E-6 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 SUPERFAMILY SSF52540 116 628 8.52E-110 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 SMART SM00847 501 598 1.2E-30 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 MADE_1008535 9b77c50fff96b8b1f619f49ca1b643bc 1342 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 75 1338 0.0 T 13-10-2018 IPR010222 RNA helicase HrpA GO:0004004 MADE_1020140 58e45b1a32c0d83a272c9cee707c8c0d 290 Gene3D G3DSA:3.40.190.10 165 261 3.0E-30 T 13-10-2018 MADE_1020140 58e45b1a32c0d83a272c9cee707c8c0d 290 SUPERFAMILY SSF53850 89 284 1.09E-33 T 13-10-2018 MADE_1020140 58e45b1a32c0d83a272c9cee707c8c0d 290 SUPERFAMILY SSF46785 1 84 4.74E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1020140 58e45b1a32c0d83a272c9cee707c8c0d 290 Gene3D G3DSA:3.40.190.10 90 284 3.0E-30 T 13-10-2018 MADE_1020140 58e45b1a32c0d83a272c9cee707c8c0d 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.7E-15 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1020140 58e45b1a32c0d83a272c9cee707c8c0d 290 Pfam PF03466 LysR substrate binding domain 87 284 1.3E-37 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1020140 58e45b1a32c0d83a272c9cee707c8c0d 290 Gene3D G3DSA:1.10.10.10 1 83 1.0E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015315 d02cd31ba6822b149b8ba596293ff304 242 SUPERFAMILY SSF88697 2 68 3.73E-15 T 13-10-2018 IPR015947 PUA-like superfamily MADE_1015315 d02cd31ba6822b149b8ba596293ff304 242 SUPERFAMILY SSF75217 75 242 1.83E-53 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_1015315 d02cd31ba6822b149b8ba596293ff304 242 Gene3D G3DSA:3.40.1280.10 74 242 4.2E-62 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_1015315 d02cd31ba6822b149b8ba596293ff304 242 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 3 241 7.3E-70 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MADE_1015315 d02cd31ba6822b149b8ba596293ff304 242 Gene3D G3DSA:2.40.240.20 1 68 3.2E-21 T 13-10-2018 MADE_1015315 d02cd31ba6822b149b8ba596293ff304 242 Pfam PF04452 RNA methyltransferase 19 237 1.2E-73 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MADE_1015315 d02cd31ba6822b149b8ba596293ff304 242 PIRSF PIRSF015601 2 241 3.2E-61 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 Gene3D G3DSA:3.30.1370.120 25 189 3.6E-51 T 13-10-2018 IPR038591 NolW-like superfamily MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 Pfam PF03958 Bacterial type II/III secretion system short domain 269 349 1.5E-16 T 13-10-2018 IPR005644 NolW-like MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 Pfam PF03958 Bacterial type II/III secretion system short domain 129 190 1.7E-8 T 13-10-2018 IPR005644 NolW-like MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 Pfam PF03958 Bacterial type II/III secretion system short domain 194 262 2.6E-14 T 13-10-2018 IPR005644 NolW-like MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 Gene3D G3DSA:3.30.1370.120 262 351 5.6E-17 T 13-10-2018 IPR038591 NolW-like superfamily MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 Gene3D G3DSA:3.30.1370.120 192 261 3.1E-20 T 13-10-2018 IPR038591 NolW-like superfamily MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 Pfam PF00263 Bacterial type II and III secretion system protein 453 614 1.3E-52 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 559 592 - T 13-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 PRINTS PR00811 Bacterial general secretion pathway protein D signature 449 473 1.6E-36 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 PRINTS PR00811 Bacterial general secretion pathway protein D signature 349 359 1.6E-36 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 PRINTS PR00811 Bacterial general secretion pathway protein D signature 578 596 1.6E-36 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 PRINTS PR00811 Bacterial general secretion pathway protein D signature 484 494 1.6E-36 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 PRINTS PR00811 Bacterial general secretion pathway protein D signature 601 615 1.6E-36 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1019825 0ca222eba9379b70dafe07eba68b1245 681 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 34 623 4.3E-160 T 13-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 MADE_1019580 e478eca73a50680f50a036067d01c38c 205 Pfam PF00510 Cytochrome c oxidase subunit III 18 203 3.8E-14 T 13-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019580 e478eca73a50680f50a036067d01c38c 205 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 26 205 3.0E-82 T 13-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 MADE_1019580 e478eca73a50680f50a036067d01c38c 205 SUPERFAMILY SSF81452 12 203 2.35E-57 T 13-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019580 e478eca73a50680f50a036067d01c38c 205 Gene3D G3DSA:1.20.120.80 20 205 1.0E-56 T 13-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016265 d4351698892fcc6ee2208c43622ab022 647 Gene3D G3DSA:2.40.170.20 148 647 8.7E-49 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1016265 d4351698892fcc6ee2208c43622ab022 647 SUPERFAMILY SSF56935 29 647 5.86E-85 T 13-10-2018 MADE_1016265 d4351698892fcc6ee2208c43622ab022 647 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 146 3.3E-22 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1016265 d4351698892fcc6ee2208c43622ab022 647 Gene3D G3DSA:2.170.130.10 24 147 6.2E-33 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1016265 d4351698892fcc6ee2208c43622ab022 647 Pfam PF00593 TonB dependent receptor 195 646 3.9E-37 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1001175 0fe60b81e6f212a5b9cc1734c06ea6ca 885 SUPERFAMILY SSF56935 36 883 1.28E-87 T 13-10-2018 MADE_1001175 0fe60b81e6f212a5b9cc1734c06ea6ca 885 Pfam PF00593 TonB dependent receptor 409 883 1.5E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1001175 0fe60b81e6f212a5b9cc1734c06ea6ca 885 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 154 1.3E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1001175 0fe60b81e6f212a5b9cc1734c06ea6ca 885 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 43 884 8.4E-183 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_1001175 0fe60b81e6f212a5b9cc1734c06ea6ca 885 Gene3D G3DSA:2.170.130.10 28 166 3.0E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_000001022410 6c7fec22703f62652083609c1320e8c7 332 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 272 3.2E-99 T 13-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis MADE_000001022410 6c7fec22703f62652083609c1320e8c7 332 SUPERFAMILY SSF52540 9 183 1.24E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022410 6c7fec22703f62652083609c1320e8c7 332 Gene3D G3DSA:1.10.1580.10 174 266 1.3E-21 T 13-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily MADE_000001022410 6c7fec22703f62652083609c1320e8c7 332 Gene3D G3DSA:3.40.50.300 3 171 1.7E-40 T 13-10-2018 MADE_000001022410 6c7fec22703f62652083609c1320e8c7 332 PIRSF PIRSF006230 274 332 170.0 T 13-10-2018 IPR016478 GTPase, MTG1 MADE_000001022410 6c7fec22703f62652083609c1320e8c7 332 PIRSF PIRSF006230 1 277 1.1E-96 T 13-10-2018 IPR016478 GTPase, MTG1 MADE_000001022410 6c7fec22703f62652083609c1320e8c7 332 Pfam PF01926 50S ribosome-binding GTPase 117 175 7.4E-13 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1015635 70a78e8b2f7c817959fd40e8f1477bc3 362 Pfam PF00534 Glycosyl transferases group 1 177 339 1.0E-34 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1015635 70a78e8b2f7c817959fd40e8f1477bc3 362 Gene3D G3DSA:3.40.50.2000 152 348 3.7E-49 T 13-10-2018 MADE_1015635 70a78e8b2f7c817959fd40e8f1477bc3 362 SUPERFAMILY SSF53756 54 361 6.28E-55 T 13-10-2018 MADE_1011730 620cf24825885f85ea57912ca40c67da 530 SUPERFAMILY SSF160574 387 499 1.15E-11 T 13-10-2018 MADE_1011730 620cf24825885f85ea57912ca40c67da 530 SUPERFAMILY SSF49899 43 356 6.25E-45 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MADE_1011730 620cf24825885f85ea57912ca40c67da 530 Pfam PF08787 Alginate lyase 43 355 2.2E-79 T 13-10-2018 IPR014895 Alginate lyase 2 MADE_1011730 620cf24825885f85ea57912ca40c67da 530 Gene3D G3DSA:2.60.120.1610 45 363 3.6E-92 T 13-10-2018 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 Gene3D G3DSA:1.20.120.530 80 236 2.7E-35 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 SMART SM00345 12 71 5.8E-24 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 Pfam PF07840 FadR C-terminal domain 72 234 1.8E-65 T 13-10-2018 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 6.1E-21 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 TIGRFAM TIGR02812 fadR_gamma: fatty acid metabolism transcriptional regulator FadR 2 235 2.8E-112 T 13-10-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 2.7E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 2.7E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 SUPERFAMILY SSF48008 79 230 2.22E-53 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 Hamap MF_00696 Fatty acid metabolism regulator protein [fadR]. 1 236 147.642 T 13-10-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 SUPERFAMILY SSF46785 11 87 6.15E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1012160 a17cee1e89a0c81f2295a73d9716d6c5 236 Gene3D G3DSA:1.10.10.10 1 79 3.7E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SUPERFAMILY SSF55874 487 658 2.62E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00388 433 498 1.6E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Gene3D G3DSA:1.20.120.160 957 1067 4.9E-12 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SUPERFAMILY SSF48452 61 217 1.77E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Gene3D G3DSA:1.25.40.10 230 382 5.1E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SUPERFAMILY SSF52172 817 952 4.84E-34 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 PRINTS PR00344 Bacterial sensor protein C-terminal signature 585 599 4.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 657 4.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 PRINTS PR00344 Bacterial sensor protein C-terminal signature 620 638 4.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 PRINTS PR00344 Bacterial sensor protein C-terminal signature 603 613 4.1E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Gene3D G3DSA:1.10.287.130 410 496 1.1E-23 T 13-10-2018 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SUPERFAMILY SSF47226 915 1056 1.57E-11 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Gene3D G3DSA:1.25.40.10 38 227 1.1E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SUPERFAMILY SSF47384 420 499 4.12E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Gene3D G3DSA:3.30.565.10 497 663 1.0E-50 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00387 545 660 2.3E-38 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 545 659 1.7E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Pfam PF00512 His Kinase A (phospho-acceptor) domain 433 498 1.8E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00448 819 932 2.6E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00448 676 794 9.4E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00028 112 145 34.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00028 151 184 90.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00028 191 224 32.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SMART SM00028 230 263 7.4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SUPERFAMILY SSF48452 185 372 2.32E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Pfam PF00072 Response regulator receiver domain 821 929 2.5E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Pfam PF00072 Response regulator receiver domain 678 794 1.4E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Gene3D G3DSA:3.40.50.2300 815 953 1.1E-36 T 13-10-2018 MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 SUPERFAMILY SSF52172 674 797 3.56E-24 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014235 38f77fce3d82e7a94ea90b4fb29bfc1d 1070 Gene3D G3DSA:3.40.50.2300 664 808 9.3E-27 T 13-10-2018 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 202 555 4.4E-104 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 Gene3D G3DSA:3.90.226.10 327 552 5.4E-57 T 13-10-2018 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 Pfam PF03572 Peptidase family S41 365 532 3.8E-51 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 241 322 6.6E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 Gene3D G3DSA:2.30.42.10 237 324 4.2E-15 T 13-10-2018 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 SMART SM00228 248 325 1.8E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 539 671 7.6E-38 T 13-10-2018 IPR020992 Tail specific protease, C-terminal MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 SMART SM00245 329 535 1.6E-59 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 SUPERFAMILY SSF50156 238 323 1.87E-12 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1010135 1225994fb6ccd587d72aa74e479844a3 680 SUPERFAMILY SSF52096 172 539 1.19E-68 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 Gene3D G3DSA:3.40.50.300 259 497 1.1E-40 T 13-10-2018 MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 SUPERFAMILY SSF52540 27 185 2.94E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 Gene3D G3DSA:3.40.50.300 5 225 2.5E-19 T 13-10-2018 MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 SUPERFAMILY SSF52540 273 492 6.32E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 Pfam PF00005 ABC transporter 31 164 1.0E-11 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 SMART SM00382 29 227 3.0E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 SMART SM00382 303 496 1.6 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012035 00b35154dcac90017c1fb053ac122cc3 497 Pfam PF00005 ABC transporter 295 447 2.9E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_000001022910 c3896748ae3c088c69ca482d8a4cbdf4 362 Hamap MF_01699 Pyrimidine monooxygenase RutA [rutA]. 1 360 66.154 T 13-10-2018 IPR019914 Pyrimidine monooxygenase RutA GO:0004497|GO:0006212|GO:0055114 KEGG: 00240+1.14.99.46 MADE_000001022910 c3896748ae3c088c69ca482d8a4cbdf4 362 Pfam PF00296 Luciferase-like monooxygenase 1 318 1.8E-69 T 13-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MADE_000001022910 c3896748ae3c088c69ca482d8a4cbdf4 362 TIGRFAM TIGR03612 RutA: pyrimidine utilization protein A 1 354 8.7E-206 T 13-10-2018 IPR019914 Pyrimidine monooxygenase RutA GO:0004497|GO:0006212|GO:0055114 KEGG: 00240+1.14.99.46 MADE_000001022910 c3896748ae3c088c69ca482d8a4cbdf4 362 SUPERFAMILY SSF51679 1 352 9.55E-78 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MADE_000001022910 c3896748ae3c088c69ca482d8a4cbdf4 362 Gene3D G3DSA:3.20.20.30 1 357 1.8E-81 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MADE_000001022235 91b92fe3f6ae0bc7ced02e7e01c8e414 254 Pfam PF09836 Putative DNA-binding domain 8 97 1.6E-19 T 13-10-2018 IPR018640 Putative DNA-binding domain, bacteria MADE_000001022235 91b92fe3f6ae0bc7ced02e7e01c8e414 254 Gene3D G3DSA:1.10.10.2180 130 254 1.7E-5 T 13-10-2018 MADE_000001022235 91b92fe3f6ae0bc7ced02e7e01c8e414 254 Gene3D G3DSA:1.10.150.690 33 127 2.0E-25 T 13-10-2018 MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 Gene3D G3DSA:3.30.230.10 1 178 8.9E-52 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 11 296 2.9E-79 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 Gene3D G3DSA:3.30.70.890 180 298 4.9E-30 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 10 290 31.319 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 Pfam PF08544 GHMP kinases C terminal 224 277 1.2E-4 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 SUPERFAMILY SSF54211 11 177 1.59E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 SUPERFAMILY SSF55060 181 295 1.53E-33 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 Pfam PF00288 GHMP kinases N terminal domain 107 163 5.9E-9 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MADE_1007595 052f8c638480792668c7cbe0d3f49958 301 PIRSF PIRSF010376 9 298 1.7E-80 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 Gene3D G3DSA:3.30.930.10 11 468 2.2E-218 T 13-10-2018 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 Pfam PF03129 Anticodon binding domain 478 571 9.7E-21 T 13-10-2018 IPR004154 Anticodon-binding MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 569 3.6E-228 T 13-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 SUPERFAMILY SSF52954 466 570 1.66E-30 T 13-10-2018 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 6.6E-20 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 6.6E-20 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 6.6E-20 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 6.6E-20 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 462 2.1E-49 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 572 38.882 T 13-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 Gene3D G3DSA:3.40.50.800 4 557 2.2E-218 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 Gene3D G3DSA:3.90.960.10 240 392 2.2E-218 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 SUPERFAMILY SSF55681 10 481 1.1E-107 T 13-10-2018 MADE_1005295 faaa30d4ecd9e0be8fef9982e80bd453 572 SUPERFAMILY SSF55826 297 401 1.96E-8 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 SMART SM00840 342 402 3.7E-24 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 460 38.666 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 2.9E-136 T 13-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 459 1.1E-181 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 7.0E-30 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 7.0E-30 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 7.0E-30 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 7.0E-30 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 Gene3D G3DSA:1.20.120.640 306 459 2.2E-45 T 13-10-2018 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 SUPERFAMILY SSF52374 2 312 4.83E-102 T 13-10-2018 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 Pfam PF09190 DALR domain 342 402 4.5E-19 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 SUPERFAMILY SSF47323 316 459 7.19E-36 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1010015 0abf3a6f46f2aae222d5dedb16d72f8e 460 Gene3D G3DSA:3.40.50.620 1 305 2.2E-135 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Pfam PF02743 Cache domain 44 261 1.0E-12 T 13-10-2018 IPR033479 Double Cache domain 1 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Gene3D G3DSA:3.40.50.2300 919 1069 2.7E-35 T 13-10-2018 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 368 479 1.6E-5 T 13-10-2018 IPR000014 PAS domain MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SMART SM00448 918 1039 4.6E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Gene3D G3DSA:1.20.120.160 1129 1235 2.5E-11 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SMART SM00388 512 577 2.6E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Gene3D G3DSA:3.30.450.20 354 478 1.0E-12 T 13-10-2018 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SUPERFAMILY SSF55874 566 736 6.42E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 PRINTS PR00344 Bacterial sensor protein C-terminal signature 700 718 3.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 PRINTS PR00344 Bacterial sensor protein C-terminal signature 724 737 3.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 693 3.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 PRINTS PR00344 Bacterial sensor protein C-terminal signature 665 679 3.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SUPERFAMILY SSF47384 498 578 6.28E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Gene3D G3DSA:1.10.287.130 479 575 2.8E-25 T 13-10-2018 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SUPERFAMILY SSF103190 63 227 1.18E-36 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Pfam PF00512 His Kinase A (phospho-acceptor) domain 513 577 1.1E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Pfam PF00989 PAS fold 368 471 1.6E-5 T 13-10-2018 IPR013767 PAS fold GO:0006355 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Pfam PF00072 Response regulator receiver domain 921 1039 4.8E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SMART SM00387 624 740 2.3E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SUPERFAMILY SSF52172 917 1043 3.56E-32 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SUPERFAMILY SSF47226 1131 1233 1.62E-13 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Gene3D G3DSA:3.30.450.20 98 228 1.2E-35 T 13-10-2018 MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 SUPERFAMILY SSF55785 375 483 3.49E-10 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 625 739 2.0E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1008485 8e366231c550dbff83dd5ce1ddc3c660 1236 Gene3D G3DSA:3.30.565.10 576 743 2.8E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014545 2de851320ae9d69a09ff09d17ee140fe 798 SUPERFAMILY SSF49265 78 172 2.86E-5 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MADE_1014545 2de851320ae9d69a09ff09d17ee140fe 798 Pfam PF12421 Fibronectin type III protein 618 661 8.1E-12 T 13-10-2018 IPR021034 Domain of unknown function, DUF3672 MADE_1014545 2de851320ae9d69a09ff09d17ee140fe 798 Pfam PF09327 Domain of unknown function (DUF1983) 479 548 5.6E-7 T 13-10-2018 IPR015406 Domain of unknown function DUF1983 MADE_1010330 d62db3806cb5555d75d8c61d999aaf08 234 SUPERFAMILY SSF46689 186 229 2.51E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1010330 d62db3806cb5555d75d8c61d999aaf08 234 SMART SM00342 147 229 4.6E-11 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1010330 d62db3806cb5555d75d8c61d999aaf08 234 Pfam PF12833 Helix-turn-helix domain 155 230 5.0E-13 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1010330 d62db3806cb5555d75d8c61d999aaf08 234 Gene3D G3DSA:1.10.10.60 131 231 3.5E-15 T 13-10-2018 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 Gene3D G3DSA:1.10.1440.20 562 619 1.8E-8 T 13-10-2018 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 SUPERFAMILY SSF53732 23 587 4.84E-187 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 Gene3D G3DSA:3.20.19.10 620 858 2.6E-81 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 Pfam PF00330 Aconitase family (aconitate hydratase) 70 533 8.2E-146 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 859 0.0 T 13-10-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 SUPERFAMILY SSF52016 599 857 6.47E-66 T 13-10-2018 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 Gene3D G3DSA:3.30.499.20 10 359 4.7E-131 T 13-10-2018 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 191 204 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 360 374 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 138 151 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 402 413 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 205 220 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 464 477 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 267 280 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 281 294 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 PRINTS PR00415 Aconitase family signature 162 170 3.2E-27 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 Pfam PF00694 Aconitase C-terminal domain 657 787 3.5E-29 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MADE_1015710 a92ae6cbb93476dfd51d4ffc6595ea2e 863 Gene3D G3DSA:3.30.499.10 361 561 5.0E-77 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1020500 2f14904bcc45e81fa1d59a1350e10302 264 SUPERFAMILY SSF52540 2 258 9.7E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020500 2f14904bcc45e81fa1d59a1350e10302 264 Gene3D G3DSA:3.40.50.300 1 262 3.6E-77 T 13-10-2018 MADE_1020500 2f14904bcc45e81fa1d59a1350e10302 264 PIRSF PIRSF009320 90 263 2.7E-8 T 13-10-2018 MADE_1020500 2f14904bcc45e81fa1d59a1350e10302 264 PIRSF PIRSF009320 2 96 1.1E-14 T 13-10-2018 MADE_1020500 2f14904bcc45e81fa1d59a1350e10302 264 Pfam PF13614 AAA domain 3 178 8.7E-63 T 13-10-2018 IPR025669 AAA domain MADE_1014070 085a72adb19d076bb4673bbd16166b8a 661 Pfam PF01295 Adenylate cyclase, class-I 248 590 1.0E-54 T 13-10-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 MADE_1014070 085a72adb19d076bb4673bbd16166b8a 661 Pfam PF12633 Adenylate cyclase NT domain 19 219 5.7E-52 T 13-10-2018 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 MADE_1018160 bb88c8690d2ee5a4cda6a7af3686f511 233 Pfam PF03352 Methyladenine glycosylase 45 141 8.7E-15 T 13-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MADE_1018160 bb88c8690d2ee5a4cda6a7af3686f511 233 SUPERFAMILY SSF48150 42 188 4.08E-37 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MADE_1018160 bb88c8690d2ee5a4cda6a7af3686f511 233 Gene3D G3DSA:1.10.340.30 38 168 1.2E-17 T 13-10-2018 MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 SUPERFAMILY SSF50939 35 417 1.02E-62 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 SUPERFAMILY SSF110296 503 719 2.88E-39 T 13-10-2018 MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 Gene3D G3DSA:2.130.10.10 32 198 2.3E-36 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 Gene3D G3DSA:2.130.10.10 485 717 3.9E-34 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 Pfam PF15902 Sortilin, neurotensin receptor 3, 129 255 1.1E-11 T 13-10-2018 IPR031778 Sortilin, N-terminal MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 Pfam PF15902 Sortilin, neurotensin receptor 3, 289 393 3.4E-10 T 13-10-2018 IPR031778 Sortilin, N-terminal MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 Gene3D G3DSA:2.130.10.10 199 312 1.1E-20 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1014140 abc05f2600c2a13000a5aecea893710f 1084 Gene3D G3DSA:2.130.10.10 313 439 6.5E-11 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1011995 85e50ff667b827da4ca27547594ccdce 145 Pfam PF00583 Acetyltransferase (GNAT) family 39 127 2.2E-10 T 13-10-2018 IPR000182 GNAT domain MADE_1011995 85e50ff667b827da4ca27547594ccdce 145 SUPERFAMILY SSF55729 1 135 1.86E-24 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1011995 85e50ff667b827da4ca27547594ccdce 145 Gene3D G3DSA:3.40.630.30 43 143 3.4E-21 T 13-10-2018 MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 Pfam PF00557 Metallopeptidase family M24 182 413 3.7E-66 T 13-10-2018 IPR000994 Peptidase M24 MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 SMART SM01011 2 138 8.7E-48 T 13-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 349 361 - T 13-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 Pfam PF05195 Aminopeptidase P, N-terminal domain 7 128 4.0E-33 T 13-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 SUPERFAMILY SSF53092 1 175 1.2E-44 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 Gene3D G3DSA:3.40.350.10 2 172 3.4E-48 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 Gene3D G3DSA:3.90.230.10 173 437 4.4E-100 T 13-10-2018 MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 PRINTS PR00599 Methionine aminopeptidase-1 signature 372 384 8.4E-6 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 PRINTS PR00599 Methionine aminopeptidase-1 signature 254 270 8.4E-6 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_1014490 2288c7e679988a095c614a297aa88dc8 437 SUPERFAMILY SSF55920 176 435 4.06E-84 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like MADE_1002385 dd311fe11818018a7e449028a0783126 421 SUPERFAMILY SSF53955 28 339 1.25E-99 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1002385 dd311fe11818018a7e449028a0783126 421 Pfam PF13406 Transglycosylase SLT domain 43 334 2.1E-107 T 13-10-2018 IPR031304 Transglycosylase SLT domain 2 MADE_1002385 dd311fe11818018a7e449028a0783126 421 Gene3D G3DSA:1.10.101.10 351 413 4.8E-11 T 13-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 MADE_1002385 dd311fe11818018a7e449028a0783126 421 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 43 338 3.3E-112 T 13-10-2018 IPR011970 Lytic murein transglycosylase MADE_1002385 dd311fe11818018a7e449028a0783126 421 Gene3D G3DSA:1.10.530.10 85 333 2.7E-87 T 13-10-2018 MADE_1002385 dd311fe11818018a7e449028a0783126 421 Pfam PF01471 Putative peptidoglycan binding domain 354 409 2.3E-9 T 13-10-2018 IPR002477 Peptidoglycan binding-like MADE_1002385 dd311fe11818018a7e449028a0783126 421 Gene3D G3DSA:1.10.8.350 53 218 2.7E-87 T 13-10-2018 MADE_1002385 dd311fe11818018a7e449028a0783126 421 SUPERFAMILY SSF47090 350 412 3.14E-14 T 13-10-2018 IPR036365 PGBD-like superfamily MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 Pfam PF17092 Penicillin-binding protein OB-like domain 350 449 1.3E-24 T 13-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 65 771 6.4E-160 T 13-10-2018 MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 Gene3D G3DSA:1.10.3810.10 48 245 3.9E-74 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 SUPERFAMILY SSF53955 43 255 1.57E-73 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 Pfam PF00912 Transglycosylase 55 229 1.0E-59 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 Pfam PF00905 Penicillin binding protein transpeptidase domain 451 635 5.2E-24 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 Gene3D G3DSA:3.40.710.10 248 324 1.0E-5 T 13-10-2018 MADE_1002595 cc4fe8c8529fbe07ae87f011e5c2dfd7 887 SUPERFAMILY SSF56601 211 865 2.6E-109 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1009475 63bc8ec65eb6b4065c03f799a144000b 124 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 3 121 5.6E-40 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009475 63bc8ec65eb6b4065c03f799a144000b 124 Gene3D G3DSA:1.20.1300.10 1 124 7.5E-40 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009475 63bc8ec65eb6b4065c03f799a144000b 124 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 5 29 - T 13-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009475 63bc8ec65eb6b4065c03f799a144000b 124 SUPERFAMILY SSF81343 2 124 4.74E-33 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009475 63bc8ec65eb6b4065c03f799a144000b 124 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 80 93 - T 13-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009475 63bc8ec65eb6b4065c03f799a144000b 124 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2 119 3.3E-29 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009475 63bc8ec65eb6b4065c03f799a144000b 124 PIRSF PIRSF000178 1 124 1.1E-29 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 SMART SM00829 26 381 0.0046 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 SUPERFAMILY SSF50129 13 199 5.63E-73 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 SUPERFAMILY SSF51735 174 347 4.48E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 Gene3D G3DSA:3.90.180.10 20 378 1.3E-152 T 13-10-2018 MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 Gene3D G3DSA:3.40.50.720 188 326 1.3E-152 T 13-10-2018 MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 75 89 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 16 383 7.8E-229 T 13-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 SUPERFAMILY SSF50129 332 382 3.01E-11 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 Pfam PF00107 Zinc-binding dehydrogenase 211 331 3.4E-26 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1015495 c5bfc098799c07607f861bd48ae07b5d 385 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 42 168 8.1E-26 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_000001021080 63c0e3466d2272e599aab710616d3038 362 SUPERFAMILY SSF51569 9 346 6.87E-133 T 13-10-2018 MADE_000001021080 63c0e3466d2272e599aab710616d3038 362 Gene3D G3DSA:3.20.20.70 3 350 1.2E-149 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_000001021080 63c0e3466d2272e599aab710616d3038 362 PIRSF PIRSF001361 1 354 7.5E-154 T 13-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MADE_000001021080 63c0e3466d2272e599aab710616d3038 362 Pfam PF00793 DAHP synthetase I family 41 340 4.3E-98 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MADE_000001021080 63c0e3466d2272e599aab710616d3038 362 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 10 347 7.3E-150 T 13-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MADE_1003090 a59f7da939c826e3280f7003bf62ff7e 87 SUPERFAMILY SSF143011 4 83 2.22E-21 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1003090 a59f7da939c826e3280f7003bf62ff7e 87 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 6 84 4.5E-8 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1003090 a59f7da939c826e3280f7003bf62ff7e 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 84 2.5E-13 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1003090 a59f7da939c826e3280f7003bf62ff7e 87 Gene3D G3DSA:3.30.2310.20 2 87 2.1E-22 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 449 4.4E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 SUPERFAMILY SSF47384 204 241 4.71E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 Gene3D G3DSA:1.10.287.130 186 285 3.9E-19 T 13-10-2018 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 287 2.0E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 1.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 Gene3D G3DSA:3.30.450.40 2 185 1.7E-14 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 SMART SM00387 335 450 6.5E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 SUPERFAMILY SSF55874 283 448 5.63E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 SMART SM00065 22 175 1.8E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 Pfam PF01590 GAF domain 23 163 4.7E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 SUPERFAMILY SSF55781 28 164 1.15E-17 T 13-10-2018 MADE_1011845 2c83c4a59d7786f0745d3ee8b4cecf15 450 Gene3D G3DSA:3.30.565.10 286 448 2.0E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 SUPERFAMILY SSF55347 155 310 4.19E-47 T 13-10-2018 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 146 4.1E-27 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 150 166 - T 13-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 336 36.209 T 13-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 Gene3D G3DSA:3.40.50.720 6 327 2.3E-111 T 13-10-2018 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 SUPERFAMILY SSF51735 2 183 7.74E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 164 313 8.1E-9 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 Gene3D G3DSA:3.30.360.10 154 314 2.3E-111 T 13-10-2018 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 335 1.3E-110 T 13-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_1002665 0a9d2265396999ef6d2c140a6960e268 337 SMART SM00859 3 147 6.6E-43 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MADE_1000735 4c6558b108a29c879df1bce804321b2d 243 SUPERFAMILY SSF69618 2 239 2.22E-32 T 13-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000735 4c6558b108a29c879df1bce804321b2d 243 Gene3D G3DSA:3.40.50.10090 2 233 2.9E-42 T 13-10-2018 MADE_1000735 4c6558b108a29c879df1bce804321b2d 243 Gene3D G3DSA:3.40.50.10090 31 164 2.9E-42 T 13-10-2018 MADE_1000735 4c6558b108a29c879df1bce804321b2d 243 Pfam PF02602 Uroporphyrinogen-III synthase HemD 16 235 1.7E-24 T 13-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 109 127 - T 13-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 SUPERFAMILY SSF53901 31 293 5.59E-76 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 Pfam PF00108 Thiolase, N-terminal domain 31 286 1.7E-85 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 ProSitePatterns PS00099 Thiolases active site. 397 410 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 PIRSF PIRSF000429 25 416 1.6E-111 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 33 414 1.2E-128 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 Gene3D G3DSA:3.40.47.10 151 412 4.0E-141 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 Gene3D G3DSA:3.40.47.10 33 299 4.0E-141 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 SUPERFAMILY SSF53901 295 415 3.43E-41 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008455 b28ef5e4222242322b7a0897ab7f8f26 416 Pfam PF02803 Thiolase, C-terminal domain 294 414 1.3E-46 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MADE_1012130 ef436ee32ec4d9759d14551ca8351376 221 Pfam PF13972 Bacterial transcriptional repressor 57 190 1.3E-18 T 13-10-2018 IPR025722 Bacterial transcriptional repressor TetR MADE_1012130 ef436ee32ec4d9759d14551ca8351376 221 Gene3D G3DSA:1.10.357.10 1 211 5.1E-40 T 13-10-2018 MADE_1012130 ef436ee32ec4d9759d14551ca8351376 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 2.1E-10 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1012130 ef436ee32ec4d9759d14551ca8351376 221 SUPERFAMILY SSF46689 3 65 4.36E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1012130 ef436ee32ec4d9759d14551ca8351376 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1012130 ef436ee32ec4d9759d14551ca8351376 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 1 433 36.292 T 13-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 2 432 8.9E-159 T 13-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 SUPERFAMILY SSF81891 169 403 1.57E-48 T 13-10-2018 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 Pfam PF12626 Polymerase A arginine-rich C-terminus 312 432 2.5E-39 T 13-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 Pfam PF01743 Poly A polymerase head domain 32 167 7.5E-36 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 SUPERFAMILY SSF81301 5 165 2.29E-37 T 13-10-2018 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 Gene3D G3DSA:1.10.3090.10 167 415 1.1E-93 T 13-10-2018 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 195 257 1.6E-21 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MADE_1018430 c061983a0db817fec744384dfaa46d1d 439 Gene3D G3DSA:3.30.460.10 1 164 1.0E-58 T 13-10-2018 MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 SUPERFAMILY SSF141868 437 679 2.88E-80 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 SMART SM00052 430 675 3.1E-94 T 13-10-2018 IPR001633 EAL domain MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 Gene3D G3DSA:3.20.20.450 433 679 3.2E-85 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 257 418 8.1E-39 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 Pfam PF00563 EAL domain 438 670 1.0E-65 T 13-10-2018 IPR001633 EAL domain MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 259 415 1.5E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 Gene3D G3DSA:3.30.70.270 254 432 1.0E-54 T 13-10-2018 MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 SUPERFAMILY SSF55073 264 422 1.41E-46 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001021120 082bf31674e5f2e13cca542b2cbac828 689 SMART SM00267 248 420 5.1E-58 T 13-10-2018 IPR000160 GGDEF domain MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 Gene3D G3DSA:2.30.33.40 1 96 7.3E-37 T 13-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 PRINTS PR00297 10kDa chaperonin signature 60 72 1.4E-28 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 PRINTS PR00297 10kDa chaperonin signature 25 46 1.4E-28 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 PRINTS PR00297 10kDa chaperonin signature 3 18 1.4E-28 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 PRINTS PR00297 10kDa chaperonin signature 82 95 1.4E-28 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 SMART SM00883 2 95 1.2E-49 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 24.515 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 SUPERFAMILY SSF50129 1 96 6.71E-31 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 13-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 MADE_1019630 ca04d43f03550e12557e0c97657c3313 96 Pfam PF00166 Chaperonin 10 Kd subunit 3 95 2.0E-30 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 MADE_1007340 f2870d8c2540ecd15587fdf104a30069 831 SUPERFAMILY SSF53474 587 831 4.7E-58 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007340 f2870d8c2540ecd15587fdf104a30069 831 Pfam PF00326 Prolyl oligopeptidase family 636 831 4.8E-41 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MADE_1007340 f2870d8c2540ecd15587fdf104a30069 831 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 383 543 7.7E-21 T 13-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 MADE_1007340 f2870d8c2540ecd15587fdf104a30069 831 Gene3D G3DSA:3.40.50.1820 576 831 7.4E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007340 f2870d8c2540ecd15587fdf104a30069 831 Gene3D G3DSA:2.120.10.30 38 254 3.6E-5 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1007340 f2870d8c2540ecd15587fdf104a30069 831 SUPERFAMILY SSF82171 60 573 1.7E-33 T 13-10-2018 MADE_1007340 f2870d8c2540ecd15587fdf104a30069 831 Gene3D G3DSA:2.140.10.30 256 570 2.0E-24 T 13-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 Gene3D G3DSA:3.30.300.160 24 111 3.8E-18 T 13-10-2018 MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 Pfam PF00437 Type II/IV secretion system protein 146 411 2.3E-92 T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 SUPERFAMILY SSF52540 128 516 1.19E-103 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 339 353 - T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 Gene3D G3DSA:3.30.450.90 112 244 6.9E-54 T 13-10-2018 MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 SMART SM00382 272 395 0.0019 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 SUPERFAMILY SSF160246 35 98 1.44E-14 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 Gene3D G3DSA:3.40.50.300 245 519 1.5E-120 T 13-10-2018 MADE_1019830 47d52a9e556ed0551a28bb6f4d0484e5 519 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 34 516 4.3E-220 T 13-10-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 MADE_1019950 70ed801f8529870e227e32f7649257f4 68 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 5 62 9.2E-26 T 13-10-2018 IPR012658 Conserved hypothetical protein CHP02443 MADE_1019950 70ed801f8529870e227e32f7649257f4 68 Pfam PF09526 Probable metal-binding protein (DUF2387) 6 61 8.9E-19 T 13-10-2018 IPR012658 Conserved hypothetical protein CHP02443 MADE_1013645 c3cb58f80d2763dff29ed67f31813166 217 SUPERFAMILY SSF101386 1 216 1.22E-62 T 13-10-2018 MADE_1013645 c3cb58f80d2763dff29ed67f31813166 217 Pfam PF08761 dUTPase 7 171 5.1E-28 T 13-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 MADE_1013645 c3cb58f80d2763dff29ed67f31813166 217 Gene3D G3DSA:1.10.4010.10 1 217 3.2E-69 T 13-10-2018 MADE_1018085 42c0024138475cc710ae01ca953037e8 146 Pfam PF01850 PIN domain 3 138 5.6E-9 T 13-10-2018 IPR002716 PIN domain MADE_1018085 42c0024138475cc710ae01ca953037e8 146 Gene3D G3DSA:3.40.50.1010 2 141 4.5E-12 T 13-10-2018 MADE_1018085 42c0024138475cc710ae01ca953037e8 146 SUPERFAMILY SSF88723 1 134 4.77E-14 T 13-10-2018 IPR029060 PIN-like domain superfamily MADE_1004045 fa9f453fa563457fdc236f677945139c 727 SUPERFAMILY SSF81271 389 455 1.09E-22 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Gene3D G3DSA:3.30.70.260 648 727 4.7E-16 T 13-10-2018 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 SUPERFAMILY SSF55021 653 724 2.42E-10 T 13-10-2018 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 50 723 4.2E-186 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 SUPERFAMILY SSF81301 188 400 1.8E-62 T 13-10-2018 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Gene3D G3DSA:3.10.20.30 390 463 3.8E-32 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Pfam PF04607 Region found in RelA / SpoT proteins 243 352 5.1E-36 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Pfam PF13291 ACT domain 648 724 2.0E-18 T 13-10-2018 IPR002912 ACT domain MADE_1004045 fa9f453fa563457fdc236f677945139c 727 SUPERFAMILY SSF109604 16 199 1.32E-42 T 13-10-2018 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Pfam PF02824 TGS domain 396 455 1.1E-20 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Gene3D G3DSA:1.10.3210.10 45 199 8.5E-40 T 13-10-2018 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 SMART SM00954 243 353 4.1E-63 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Pfam PF13328 HD domain 45 183 8.2E-37 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1004045 fa9f453fa563457fdc236f677945139c 727 Gene3D G3DSA:3.30.460.10 201 333 6.5E-48 T 13-10-2018 MADE_1004470 a1e318bc28a8f94dac04274e134edc41 1243 Gene3D G3DSA:3.40.50.300 2 296 1.6E-45 T 13-10-2018 MADE_1004470 a1e318bc28a8f94dac04274e134edc41 1243 Pfam PF13476 AAA domain 8 227 1.4E-27 T 13-10-2018 IPR038729 Rad50/SbcC-type AAA domain MADE_1004470 a1e318bc28a8f94dac04274e134edc41 1243 SUPERFAMILY SSF52540 3 1230 1.68E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004470 a1e318bc28a8f94dac04274e134edc41 1243 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1133 1197 7.0E-15 T 13-10-2018 MADE_1004470 a1e318bc28a8f94dac04274e134edc41 1243 Gene3D G3DSA:3.40.50.300 969 1234 1.8E-26 T 13-10-2018 MADE_1015600 61fbe60ab3674ccf935de712dad7bc75 400 Gene3D G3DSA:3.30.360.10 149 345 4.0E-146 T 13-10-2018 MADE_1015600 61fbe60ab3674ccf935de712dad7bc75 400 SUPERFAMILY SSF51735 1 189 3.55E-20 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1015600 61fbe60ab3674ccf935de712dad7bc75 400 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 135 5.5E-32 T 13-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MADE_1015600 61fbe60ab3674ccf935de712dad7bc75 400 Gene3D G3DSA:3.40.50.720 5 388 4.0E-146 T 13-10-2018 MADE_1015600 61fbe60ab3674ccf935de712dad7bc75 400 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 139 386 7.6E-38 T 13-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 22 607 2.9E-242 T 13-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Gene3D G3DSA:1.10.150.80 531 613 3.3E-25 T 13-10-2018 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 SMART SM00956 417 520 6.2E-45 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Pfam PF16124 RecQ zinc-binding 349 410 3.6E-14 T 13-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Pfam PF00570 HRDC domain 540 605 3.6E-21 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Gene3D G3DSA:1.10.10.10 416 530 7.4E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Pfam PF00271 Helicase conserved C-terminal domain 236 336 4.8E-21 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Pfam PF00270 DEAD/DEAH box helicase 35 192 6.8E-22 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 SUPERFAMILY SSF47819 535 611 4.58E-25 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Gene3D G3DSA:3.40.50.300 10 215 1.2E-79 T 13-10-2018 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 SMART SM00490 256 337 2.8E-28 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Pfam PF09382 RQC domain 412 521 7.5E-34 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 23 470 2.6E-170 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 SMART SM00487 29 225 8.9E-33 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1000965 427c38726021978b319e296a5f1b0f15 613 Gene3D G3DSA:3.40.50.300 217 415 8.8E-62 T 13-10-2018 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 SMART SM00341 535 613 1.7E-16 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MADE_1000965 427c38726021978b319e296a5f1b0f15 613 SUPERFAMILY SSF52540 72 358 9.21E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000965 427c38726021978b319e296a5f1b0f15 613 SUPERFAMILY SSF46785 408 529 6.53E-39 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1011035 562fe169865cb1a67a0307e434b9d8c8 94 Gene3D G3DSA:1.10.260.40 35 94 2.0E-18 T 13-10-2018 MADE_1011035 562fe169865cb1a67a0307e434b9d8c8 94 SMART SM00530 35 89 0.0029 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1011035 562fe169865cb1a67a0307e434b9d8c8 94 SUPERFAMILY SSF47413 37 84 1.07E-9 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1011035 562fe169865cb1a67a0307e434b9d8c8 94 Pfam PF01381 Helix-turn-helix 38 74 8.7E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 7 224 2.0E-73 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 3 238 15.989 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 ProSitePatterns PS01218 TatC family signature. 152 171 - T 13-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 83 101 5.2E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 6 33 5.2E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 101 127 5.2E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 152 180 5.2E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MADE_1002820 f89606e2ee7cc27027aeab274e6ae62b 251 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 219 6.4E-64 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 Pfam PF00453 Ribosomal protein L20 3 109 6.5E-50 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 4.0E-14 T 13-10-2018 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.2E-53 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 Gene3D G3DSA:1.10.1900.20 56 118 7.7E-30 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.2E-42 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.2E-42 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.2E-42 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 Gene3D G3DSA:1.10.720.90 2 55 9.0E-24 T 13-10-2018 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 31.084 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008095 ec5c4ad40b35955af5a63fb4c6cf5115 118 SUPERFAMILY SSF74731 3 117 1.18E-50 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002445 8ee840360a2798a4a888c3c557931b72 426 Gene3D G3DSA:3.40.640.10 69 317 4.2E-177 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1002445 8ee840360a2798a4a888c3c557931b72 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1002445 8ee840360a2798a4a888c3c557931b72 426 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 425 1.4E-195 T 13-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MADE_1002445 8ee840360a2798a4a888c3c557931b72 426 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 104.604 T 13-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 MADE_1002445 8ee840360a2798a4a888c3c557931b72 426 Pfam PF00202 Aminotransferase class-III 32 397 3.5E-78 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1002445 8ee840360a2798a4a888c3c557931b72 426 Gene3D G3DSA:3.90.1150.10 8 418 4.2E-177 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1002445 8ee840360a2798a4a888c3c557931b72 426 SUPERFAMILY SSF53383 2 424 8.9E-135 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1016590 29fdcc6e0768125a1ec2fdcf2cf8435f 441 Gene3D G3DSA:2.30.30.60 271 320 3.9E-11 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1016590 29fdcc6e0768125a1ec2fdcf2cf8435f 441 Pfam PF00924 Mechanosensitive ion channel 212 419 2.3E-44 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1016590 29fdcc6e0768125a1ec2fdcf2cf8435f 441 SUPERFAMILY SSF82689 324 430 7.98E-22 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1016590 29fdcc6e0768125a1ec2fdcf2cf8435f 441 SUPERFAMILY SSF82861 172 253 4.32E-11 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MADE_1016590 29fdcc6e0768125a1ec2fdcf2cf8435f 441 Gene3D G3DSA:3.30.70.100 322 423 2.3E-17 T 13-10-2018 MADE_1016590 29fdcc6e0768125a1ec2fdcf2cf8435f 441 SUPERFAMILY SSF50182 255 321 4.25E-14 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1010075 6b96aca050b59cd289c7d76aa6b1019b 478 Pfam PF00939 Sodium:sulfate symporter transmembrane region 25 471 6.5E-60 T 13-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MADE_1010075 6b96aca050b59cd289c7d76aa6b1019b 478 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 48 475 1.3E-74 T 13-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 MADE_1006020 f9b56aee7984d752b8b3bac768d10bf2 163 Gene3D G3DSA:2.40.50.180 38 147 3.0E-43 T 13-10-2018 MADE_1006020 f9b56aee7984d752b8b3bac768d10bf2 163 SMART SM00260 15 152 2.1E-51 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1006020 f9b56aee7984d752b8b3bac768d10bf2 163 SUPERFAMILY SSF50341 12 158 3.79E-44 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1006020 f9b56aee7984d752b8b3bac768d10bf2 163 Gene3D G3DSA:2.30.30.40 21 146 3.0E-43 T 13-10-2018 MADE_1006020 f9b56aee7984d752b8b3bac768d10bf2 163 Pfam PF01584 CheW-like domain 19 155 4.7E-42 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015715 c97d5da6df8d17873872394586dce5dd 393 Pfam PF04303 PrpF protein 7 389 3.7E-165 T 13-10-2018 IPR007400 PrpF protein MADE_1015715 c97d5da6df8d17873872394586dce5dd 393 Gene3D G3DSA:3.10.310.10 12 386 1.5E-148 T 13-10-2018 MADE_1015715 c97d5da6df8d17873872394586dce5dd 393 Gene3D G3DSA:3.10.310.10 182 372 1.5E-148 T 13-10-2018 MADE_1015715 c97d5da6df8d17873872394586dce5dd 393 SUPERFAMILY SSF54506 4 183 4.39E-69 T 13-10-2018 MADE_1015715 c97d5da6df8d17873872394586dce5dd 393 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 6 391 4.4E-218 T 13-10-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 MADE_1015715 c97d5da6df8d17873872394586dce5dd 393 SUPERFAMILY SSF54506 187 390 1.15E-74 T 13-10-2018 MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 SMART SM00267 314 477 8.1E-10 T 13-10-2018 IPR000160 GGDEF domain MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 Gene3D G3DSA:3.40.50.2300 26 170 4.4E-14 T 13-10-2018 MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 Gene3D G3DSA:3.30.70.270 319 489 9.0E-25 T 13-10-2018 MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 322 472 2.1E-13 T 13-10-2018 IPR000160 GGDEF domain MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 SMART SM00448 30 153 0.007 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 SMART SM00052 483 732 1.1E-100 T 13-10-2018 IPR001633 EAL domain MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 Gene3D G3DSA:3.20.20.450 490 741 3.0E-88 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 SUPERFAMILY SSF55073 330 477 4.87E-20 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 Pfam PF00563 EAL domain 493 727 2.4E-66 T 13-10-2018 IPR001633 EAL domain MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 Pfam PF11849 Domain of unknown function (DUF3369) 153 321 2.5E-52 T 13-10-2018 IPR021800 Domain of unknown function DUF3369 MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 Pfam PF00990 Diguanylate cyclase, GGDEF domain 325 469 8.6E-16 T 13-10-2018 IPR000160 GGDEF domain MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 SUPERFAMILY SSF52172 28 168 1.99E-12 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 Pfam PF00072 Response regulator receiver domain 32 149 8.4E-6 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016720 b0a623ef117dde1bfe704f5f85c6d4dd 741 SUPERFAMILY SSF141868 493 739 1.31E-82 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 PIRSF PIRSF001235 5 411 3.8E-127 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 Gene3D G3DSA:3.30.70.360 214 327 2.6E-132 T 13-10-2018 MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 Pfam PF01546 Peptidase family M20/M25/M40 78 406 5.7E-29 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 SUPERFAMILY SSF53187 22 408 6.58E-74 T 13-10-2018 MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 Pfam PF07687 Peptidase dimerisation domain 214 313 5.3E-6 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 SUPERFAMILY SSF55031 214 329 1.74E-27 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 Gene3D G3DSA:3.40.630.10 27 403 2.6E-132 T 13-10-2018 MADE_1008015 d91d3c32cb182cc9b0823910c71e457f 411 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 24 407 5.3E-118 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 289 303 5.3E-5 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 330 5.3E-5 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 209 224 5.3E-5 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 10 492 1.5E-174 T 13-10-2018 IPR004482 Mg chelatase-related protein MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 Gene3D G3DSA:3.30.230.10 1 163 1.4E-6 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 289 304 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 Gene3D G3DSA:3.40.50.300 187 494 1.2E-53 T 13-10-2018 MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 404 492 1.8E-26 T 13-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 SUPERFAMILY SSF52540 190 495 1.44E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 SMART SM00382 210 388 1.2E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 135 2.7E-42 T 13-10-2018 MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 SUPERFAMILY SSF54211 8 169 4.93E-26 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_000001023700 f353871c2a7419abcb55f5f8445499c4 504 Pfam PF01078 Magnesium chelatase, subunit ChlI 192 388 1.7E-84 T 13-10-2018 IPR000523 Magnesium chelatase ChlI domain MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 SUPERFAMILY SSF52540 42 352 2.08E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 34.257 T 13-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 Gene3D G3DSA:3.40.50.300 90 285 8.9E-123 T 13-10-2018 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 SMART SM00382 99 247 2.8E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 Gene3D G3DSA:1.20.120.140 4 305 8.9E-123 T 13-10-2018 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 SMART SM00963 1 86 1.4E-34 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 9.6E-75 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 SUPERFAMILY SSF47446 298 431 9.48E-47 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 7.3E-177 T 13-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 Gene3D G3DSA:1.10.260.30 328 451 6.3E-46 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 SMART SM00962 100 296 2.1E-115 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 Pfam PF02978 Signal peptide binding domain 329 427 5.3E-35 T 13-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 MADE_000001020980 18b5ae9de1d82e5ad20330a5f1b4f244 478 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.6E-21 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 Hamap MF_00124 Thymidine kinase [tdk]. 1 189 35.221 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 PIRSF PIRSF035805 1 190 2.7E-56 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 Gene3D G3DSA:3.30.60.20 144 189 6.4E-11 T 13-10-2018 MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 173 186 - T 13-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 Pfam PF00265 Thymidine kinase 2 186 4.0E-57 T 13-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 SUPERFAMILY SSF52540 1 141 2.83E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 SUPERFAMILY SSF57716 142 192 3.04E-17 T 13-10-2018 MADE_000001022365 9af586663a2cf6ae0af46247009cd3b7 193 Gene3D G3DSA:3.40.50.300 1 141 1.0E-25 T 13-10-2018 MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 SMART SM00418 21 99 2.5E-23 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 Pfam PF01022 Bacterial regulatory protein, arsR family 28 72 7.4E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 SUPERFAMILY SSF46785 16 102 1.17E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 53 2.0E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 2.0E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 2.0E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 2.0E-13 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1011525 a569a06434b8d8afcba1d4848b8fe7ee 103 Gene3D G3DSA:1.10.10.10 8 103 2.7E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1012030 11a06003f93e203494f41ab96f41bdbd 462 Pfam PF01471 Putative peptidoglycan binding domain 164 196 1.5E-9 T 13-10-2018 IPR002477 Peptidoglycan binding-like MADE_1012030 11a06003f93e203494f41ab96f41bdbd 462 SUPERFAMILY SSF141523 222 384 9.55E-21 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like MADE_1012030 11a06003f93e203494f41ab96f41bdbd 462 SUPERFAMILY SSF47090 163 203 5.41E-10 T 13-10-2018 IPR036365 PGBD-like superfamily MADE_1012030 11a06003f93e203494f41ab96f41bdbd 462 Pfam PF03734 L,D-transpeptidase catalytic domain 224 393 1.3E-28 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 SUPERFAMILY SSF56634 12 488 5.23E-194 T 13-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 ProSitePatterns PS00438 Catalase proximal active site signature. 53 69 - T 13-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 PRINTS PR00067 Catalase signature 30 53 1.1E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 PRINTS PR00067 Catalase signature 133 151 1.1E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 PRINTS PR00067 Catalase signature 114 131 1.1E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 PRINTS PR00067 Catalase signature 327 353 1.1E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 PRINTS PR00067 Catalase signature 295 322 1.1E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 PRINTS PR00067 Catalase signature 93 111 1.1E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 PIRSF PIRSF038928 7 491 4.7E-203 T 13-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 SMART SM01060 17 400 1.5E-248 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 Gene3D G3DSA:2.40.180.10 12 491 5.4E-207 T 13-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 Pfam PF06628 Catalase-related immune-responsive 428 488 1.2E-19 T 13-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1002620 1c8a2f88c622005c92f0c25e7c972bae 491 Pfam PF00199 Catalase 17 395 1.1E-175 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1012040 ae37e36ca60e7a46e164df381c04a466 435 Pfam PF02667 Short chain fatty acid transporter 1 435 2.7E-150 T 13-10-2018 IPR006160 Short chain fatty acid transporter AtoE MADE_1013595 c986104aeca71bcf8ed579d63b1eb73e 346 Gene3D G3DSA:3.20.20.210 1 343 6.1E-130 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MADE_1013595 c986104aeca71bcf8ed579d63b1eb73e 346 PIRSF PIRSF005632 1 343 3.8E-189 T 13-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit MADE_1013595 c986104aeca71bcf8ed579d63b1eb73e 346 SUPERFAMILY SSF51726 7 345 8.89E-68 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MADE_1013595 c986104aeca71bcf8ed579d63b1eb73e 346 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 329 5.8E-33 T 13-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 13-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.836 T 13-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 128 209 7.3E-5 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 126 2.9E-32 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 PIRSF PIRSF000709 3 112 5.3E-7 T 13-10-2018 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 PIRSF PIRSF000709 146 243 0.37 T 13-10-2018 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 SMART SM00855 3 189 2.3E-28 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 246 2.5E-119 T 13-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 Gene3D G3DSA:3.40.50.1240 2 248 3.9E-92 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_1002230 465778ac7f3ee262f41705bc2d015393 248 SUPERFAMILY SSF53254 1 245 6.38E-81 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_1020345 1628a3811696198619e49dc71680c0e0 796 Pfam PF00271 Helicase conserved C-terminal domain 406 522 2.4E-6 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1020345 1628a3811696198619e49dc71680c0e0 796 SUPERFAMILY SSF52540 277 528 1.83E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020345 1628a3811696198619e49dc71680c0e0 796 Gene3D G3DSA:3.40.50.300 137 338 5.8E-88 T 13-10-2018 MADE_1020345 1628a3811696198619e49dc71680c0e0 796 SMART SM00487 154 356 2.8E-16 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1020345 1628a3811696198619e49dc71680c0e0 796 Pfam PF04851 Type III restriction enzyme, res subunit 156 321 9.5E-36 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MADE_1020345 1628a3811696198619e49dc71680c0e0 796 Gene3D G3DSA:3.40.50.300 339 568 5.9E-65 T 13-10-2018 MADE_1020345 1628a3811696198619e49dc71680c0e0 796 Pfam PF08463 EcoEI R protein C-terminal 637 793 6.4E-23 T 13-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MADE_1020345 1628a3811696198619e49dc71680c0e0 796 Gene3D G3DSA:3.90.1570.30 1 136 5.5E-60 T 13-10-2018 MADE_1020345 1628a3811696198619e49dc71680c0e0 796 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 32 116 5.7E-8 T 13-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain MADE_1020345 1628a3811696198619e49dc71680c0e0 796 SUPERFAMILY SSF52540 147 362 1.81E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006635 eefa022743c73b97303e6eccef1fafdf 230 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 9 208 8.5E-84 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 MADE_1006635 eefa022743c73b97303e6eccef1fafdf 230 PIRSF PIRSF006102 2 219 2.0E-76 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_1006635 eefa022743c73b97303e6eccef1fafdf 230 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 1 210 27.701 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 MADE_1006635 eefa022743c73b97303e6eccef1fafdf 230 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 200 6.6E-65 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_1006935 17c644d67f9625b4d909bbcc6ff79ad4 190 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 129 164 5.4E-11 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1006935 17c644d67f9625b4d909bbcc6ff79ad4 190 Gene3D G3DSA:2.160.10.10 1 184 2.1E-68 T 13-10-2018 MADE_1006935 17c644d67f9625b4d909bbcc6ff79ad4 190 Pfam PF12464 Maltose acetyltransferase 6 57 1.3E-13 T 13-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MADE_1006935 17c644d67f9625b4d909bbcc6ff79ad4 190 SMART SM01266 4 58 3.6E-18 T 13-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 MADE_1006935 17c644d67f9625b4d909bbcc6ff79ad4 190 SUPERFAMILY SSF51161 2 183 4.02E-49 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 SUPERFAMILY SSF88697 275 364 3.65E-21 T 13-10-2018 IPR015947 PUA-like superfamily MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 Gene3D G3DSA:2.30.130.10 264 365 1.9E-30 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 Gene3D G3DSA:3.40.1160.10 4 263 2.9E-75 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 4.6E-37 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 PRINTS PR00474 Glutamate 5-kinase family signature 114 135 4.6E-37 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 PRINTS PR00474 Glutamate 5-kinase family signature 207 227 4.6E-37 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 PRINTS PR00474 Glutamate 5-kinase family signature 146 173 4.6E-37 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 ProSitePatterns PS00902 Glutamate 5-kinase signature. 205 222 - T 13-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 SMART SM00359 275 357 1.1E-15 T 13-10-2018 IPR002478 PUA domain GO:0003723 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 SUPERFAMILY SSF53633 7 253 3.8E-59 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 Hamap MF_00456 Glutamate 5-kinase [proB]. 7 261 32.583 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 PIRSF PIRSF000729 3 365 2.5E-120 T 13-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 Pfam PF01472 PUA domain 275 348 8.4E-19 T 13-10-2018 IPR002478 PUA domain GO:0003723 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 Pfam PF00696 Amino acid kinase family 8 233 9.1E-36 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MADE_1020200 b3ad0d1d6471dbeca3c56939fd8a889c 365 TIGRFAM TIGR01027 proB: glutamate 5-kinase 7 364 6.2E-118 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 391 9.8E-14 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 Gene3D G3DSA:3.40.1190.10 83 314 3.8E-74 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 Gene3D G3DSA:3.40.1390.10 1 82 7.8E-21 T 13-10-2018 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 SUPERFAMILY SSF53244 317 451 1.56E-33 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 SUPERFAMILY SSF53623 103 312 2.75E-54 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 Gene3D G3DSA:3.90.190.20 316 456 8.1E-42 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 SUPERFAMILY SSF63418 1 99 1.57E-22 T 13-10-2018 IPR035911 MurE/MurF, N-terminal MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 Pfam PF01225 Mur ligase family, catalytic domain 28 92 2.3E-9 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 453 32.91 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 451 2.1E-138 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015170 44951007c74c3445c77c3832ec37e8fe 469 Pfam PF08245 Mur ligase middle domain 107 296 1.4E-48 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MADE_000001022965 ce8e4da039c82a1bbe6cc1352cb76404 202 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 200 3.5E-55 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_000001022965 ce8e4da039c82a1bbe6cc1352cb76404 202 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 201 1.3E-97 T 13-10-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MADE_000001022965 ce8e4da039c82a1bbe6cc1352cb76404 202 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 202 28.429 T 13-10-2018 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 MADE_000001022965 ce8e4da039c82a1bbe6cc1352cb76404 202 PIRSF PIRSF006102 1 202 1.1E-59 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_1019555 fc36f392ed37e58960bdf5e405129e04 368 Pfam PF04773 FecR protein 146 236 2.6E-20 T 13-10-2018 IPR006860 FecR protein MADE_1019555 fc36f392ed37e58960bdf5e405129e04 368 Pfam PF16344 Domain of unknown function (DUF4974) 278 363 1.4E-7 T 13-10-2018 IPR032508 Protein FecR, C-terminal MADE_1019555 fc36f392ed37e58960bdf5e405129e04 368 Gene3D G3DSA:3.55.50.30 293 367 8.7E-7 T 13-10-2018 MADE_1019555 fc36f392ed37e58960bdf5e405129e04 368 Gene3D G3DSA:2.60.120.1440 125 279 9.2E-22 T 13-10-2018 MADE_1019555 fc36f392ed37e58960bdf5e405129e04 368 PIRSF PIRSF018266 20 368 2.4E-62 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MADE_1018935 c3251f8eec54348fce40e6702f37df46 363 Pfam PF12706 Beta-lactamase superfamily domain 115 318 4.2E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1018935 c3251f8eec54348fce40e6702f37df46 363 Gene3D G3DSA:3.60.15.10 73 363 5.4E-63 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1018935 c3251f8eec54348fce40e6702f37df46 363 SMART SM00849 101 308 0.0041 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1018935 c3251f8eec54348fce40e6702f37df46 363 SUPERFAMILY SSF56281 96 323 1.15E-26 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 Pfam PF00171 Aldehyde dehydrogenase family 6 281 2.7E-19 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 Gene3D G3DSA:3.40.309.10 224 372 9.3E-153 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 SUPERFAMILY SSF53720 4 414 7.33E-113 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 39.564 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 1.3E-135 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 343 - T 13-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 Gene3D G3DSA:3.40.605.10 10 411 9.3E-153 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1009190 372a3c767c98f482cc370872e28e9a3c 415 PIRSF PIRSF000151 1 415 4.5E-165 T 13-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MADE_000001021830 550089450479b6e1e321747f2c84a445 230 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 16 228 2.4E-38 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MADE_000001021830 550089450479b6e1e321747f2c84a445 230 Gene3D G3DSA:3.40.50.620 10 229 1.3E-57 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_000001021830 550089450479b6e1e321747f2c84a445 230 Pfam PF01467 Cytidylyltransferase-like 16 191 1.3E-26 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MADE_000001021830 550089450479b6e1e321747f2c84a445 230 SUPERFAMILY SSF52374 13 229 7.51E-44 T 13-10-2018 MADE_000001021830 550089450479b6e1e321747f2c84a445 230 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 12 229 26.106 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Pfam PF01584 CheW-like domain 535 661 4.6E-23 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Gene3D G3DSA:1.20.120.160 1 145 3.5E-40 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Gene3D G3DSA:2.40.50.180 553 616 4.0E-39 T 13-10-2018 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Pfam PF01627 Hpt domain 10 99 9.0E-20 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SMART SM01231 282 345 7.5E-19 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Gene3D G3DSA:2.30.30.40 530 656 4.0E-39 T 13-10-2018 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 283 345 3.4E-15 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 393 529 3.9E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Gene3D G3DSA:3.30.565.10 346 529 1.5E-56 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SMART SM00260 522 661 8.9E-34 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SMART SM00387 390 530 2.0E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SUPERFAMILY SSF47226 5 129 1.31E-32 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SUPERFAMILY SSF55874 347 528 1.31E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SUPERFAMILY SSF47384 284 346 1.37E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SUPERFAMILY SSF50341 529 660 5.62E-30 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 SMART SM00073 5 102 9.2E-29 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 Gene3D G3DSA:1.10.287.560 282 345 1.1E-14 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 449 2.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 484 2.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 527 2.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002005 d8866d389e24f1671e1432f59890100a 674 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 508 2.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014300 7f8b923b65f77ab3d33aa2f5b69b5eda 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 3 231 4.7E-93 T 13-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE MADE_1014300 7f8b923b65f77ab3d33aa2f5b69b5eda 231 Gene3D G3DSA:3.40.50.300 1 230 5.7E-57 T 13-10-2018 MADE_1014300 7f8b923b65f77ab3d33aa2f5b69b5eda 231 SUPERFAMILY SSF52540 1 222 1.61E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014300 7f8b923b65f77ab3d33aa2f5b69b5eda 231 Pfam PF00005 ABC transporter 19 159 4.5E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1014300 7f8b923b65f77ab3d33aa2f5b69b5eda 231 SMART SM00382 26 218 3.2E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004300 533fb62f42053b9849878ef113ec6cd6 497 Gene3D G3DSA:3.30.70.1450 404 494 1.3E-16 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1004300 533fb62f42053b9849878ef113ec6cd6 497 Pfam PF02080 TrkA-C domain 427 483 4.6E-12 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MADE_1004300 533fb62f42053b9849878ef113ec6cd6 497 SUPERFAMILY SSF116726 418 484 1.83E-10 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1004300 533fb62f42053b9849878ef113ec6cd6 497 Pfam PF00999 Sodium/hydrogen exchanger family 22 397 2.1E-49 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MADE_1004300 533fb62f42053b9849878ef113ec6cd6 497 Gene3D G3DSA:1.20.1530.20 16 401 2.1E-17 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily MADE_1019810 f3a7e9727518531bbc1536a21338e0bc 299 Gene3D G3DSA:3.55.30.10 1 178 2.3E-55 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MADE_1019810 f3a7e9727518531bbc1536a21338e0bc 299 PIRSF PIRSF005261 1 291 7.8E-70 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MADE_1019810 f3a7e9727518531bbc1536a21338e0bc 299 SUPERFAMILY SSF64397 5 239 5.76E-61 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 MADE_1019810 f3a7e9727518531bbc1536a21338e0bc 299 Gene3D G3DSA:1.10.287.480 185 232 4.6E-18 T 13-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily MADE_1019810 f3a7e9727518531bbc1536a21338e0bc 299 SUPERFAMILY SSF118352 233 289 4.97E-17 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MADE_1019810 f3a7e9727518531bbc1536a21338e0bc 299 Pfam PF01430 Hsp33 protein 5 280 1.7E-77 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 MADE_1019810 f3a7e9727518531bbc1536a21338e0bc 299 Gene3D G3DSA:3.90.1280.10 233 291 1.9E-20 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 MADE_1000395 165edf2a1cdc262437484593d131eff1 465 Pfam PF03553 Na+/H+ antiporter family 161 455 7.3E-47 T 13-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MADE_1000395 165edf2a1cdc262437484593d131eff1 465 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 9 459 3.3E-123 T 13-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 Gene3D G3DSA:3.55.50.30 161 275 1.9E-41 T 13-10-2018 MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 Gene3D G3DSA:2.60.40.3470 45 160 5.3E-14 T 13-10-2018 MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 Pfam PF00263 Bacterial type II and III secretion system protein 428 586 5.4E-47 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 Gene3D G3DSA:3.30.1370.120 276 337 4.1E-9 T 13-10-2018 IPR038591 NolW-like superfamily MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 532 565 - T 13-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 SMART SM00965 203 251 2.8E-8 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 Pfam PF03958 Bacterial type II/III secretion system short domain 279 341 1.4E-12 T 13-10-2018 IPR005644 NolW-like MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 178 586 4.5E-153 T 13-10-2018 IPR013355 Type IV pilus secretin PilQ MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 PRINTS PR00811 Bacterial general secretion pathway protein D signature 341 351 4.7E-19 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 PRINTS PR00811 Bacterial general secretion pathway protein D signature 551 569 4.7E-19 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 PRINTS PR00811 Bacterial general secretion pathway protein D signature 574 588 4.7E-19 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1002570 6366c3a711f4df236a64258bf68fc74e 590 PRINTS PR00811 Bacterial general secretion pathway protein D signature 424 448 4.7E-19 T 13-10-2018 IPR001775 GspD/PilQ family MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 Gene3D G3DSA:3.90.400.10 186 261 3.1E-199 T 13-10-2018 MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 SUPERFAMILY SSF51011 573 647 7.85E-11 T 13-10-2018 MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 SMART SM00642 97 525 1.2E-29 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 Pfam PF16657 Maltogenic Amylase, C-terminal domain 572 645 2.2E-9 T 13-10-2018 IPR032091 Maltogenic Amylase, C-terminal MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 Gene3D G3DSA:2.60.40.1180 573 648 8.3E-20 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 Gene3D G3DSA:1.10.1740.10 9 96 3.2E-19 T 13-10-2018 MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 Pfam PF00128 Alpha amylase, catalytic domain 112 317 1.1E-37 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 Gene3D G3DSA:3.20.20.80 99 562 3.1E-199 T 13-10-2018 MADE_000001023410 857d7c3933c6bb8eaebc4154b6ecc0fa 649 SUPERFAMILY SSF51445 19 567 3.06E-116 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1008465 ee69b76f6ce182a950a8622919af8a19 411 SUPERFAMILY SSF53383 9 397 4.33E-74 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1008465 ee69b76f6ce182a950a8622919af8a19 411 Gene3D G3DSA:3.90.1150.10 11 393 2.2E-140 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1008465 ee69b76f6ce182a950a8622919af8a19 411 Pfam PF00266 Aminotransferase class-V 149 318 8.3E-15 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_1008465 ee69b76f6ce182a950a8622919af8a19 411 PIRSF PIRSF038800 2 402 2.5E-139 T 13-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MADE_1008465 ee69b76f6ce182a950a8622919af8a19 411 Gene3D G3DSA:3.40.640.10 42 299 2.2E-140 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1008465 ee69b76f6ce182a950a8622919af8a19 411 TIGRFAM TIGR01814 kynureninase: kynureninase 8 394 5.6E-82 T 13-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 SUPERFAMILY SSF55874 291 452 3.41E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 452 5.6E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 SUPERFAMILY SSF158472 185 236 1.44E-10 T 13-10-2018 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 Pfam PF00672 HAMP domain 185 234 3.3E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 SMART SM00388 239 301 5.4E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 301 3.6E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 SMART SM00387 344 453 2.4E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 SUPERFAMILY SSF47384 222 302 9.61E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 7.0E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 7.0E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 7.0E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 Gene3D G3DSA:1.10.287.130 188 302 1.3E-32 T 13-10-2018 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 SMART SM00304 184 238 1.9E-8 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1002685 00fc70d0594691fbbb3e34de604fc2b9 453 Gene3D G3DSA:3.30.565.10 305 452 4.4E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 13-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 Pfam PF08544 GHMP kinases C terminal 278 358 3.7E-9 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 119 130 - T 13-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 Pfam PF10509 Galactokinase galactose-binding signature 9 56 1.0E-22 T 13-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 SUPERFAMILY SSF54211 6 201 3.04E-62 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 SUPERFAMILY SSF55060 203 378 3.52E-50 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00473 Galactokinase signature 261 275 8.9E-29 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00473 Galactokinase signature 26 44 8.9E-29 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00473 Galactokinase signature 90 101 8.9E-29 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00473 Galactokinase signature 110 128 8.9E-29 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 TIGRFAM TIGR00131 gal_kin: galactokinase 6 377 1.6E-126 T 13-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PIRSF PIRSF000530 2 379 8.6E-117 T 13-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 Pfam PF00288 GHMP kinases N terminal domain 113 180 4.7E-15 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 Gene3D G3DSA:3.30.230.10 21 199 5.4E-125 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 Hamap MF_00246 Galactokinase [galK]. 24 379 41.385 T 13-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00959 Mevalonate kinase family signature 160 179 6.2E-44 T 13-10-2018 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00959 Mevalonate kinase family signature 24 48 6.2E-44 T 13-10-2018 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00959 Mevalonate kinase family signature 117 139 6.2E-44 T 13-10-2018 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 PRINTS PR00959 Mevalonate kinase family signature 326 343 6.2E-44 T 13-10-2018 MADE_1001140 3e13b3a947fb531988aeb72b26b3db25 379 Gene3D G3DSA:3.30.70.890 200 355 5.4E-125 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MADE_1012435 c3aedffa8ea15841ebd2b9e6323b929e 157 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 31.6 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012435 c3aedffa8ea15841ebd2b9e6323b929e 157 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 150 1.3E-57 T 13-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012435 c3aedffa8ea15841ebd2b9e6323b929e 157 SUPERFAMILY SSF52121 4 153 7.46E-60 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012435 c3aedffa8ea15841ebd2b9e6323b929e 157 Gene3D G3DSA:3.40.50.960 1 156 7.3E-63 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012435 c3aedffa8ea15841ebd2b9e6323b929e 157 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 2.2E-55 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1007275 08d0c71a3e8851f5c34664881d14dafa 240 SUPERFAMILY SSF52317 5 218 2.29E-37 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1007275 08d0c71a3e8851f5c34664881d14dafa 240 Pfam PF03575 Peptidase family S51 6 209 1.3E-58 T 13-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 MADE_1007275 08d0c71a3e8851f5c34664881d14dafa 240 Gene3D G3DSA:3.40.50.880 3 232 6.5E-54 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1009875 01ad492c0d04c6559b65158df292786f 509 SUPERFAMILY SSF117457 317 489 2.09E-62 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MADE_1009875 01ad492c0d04c6559b65158df292786f 509 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 326 488 1.6E-47 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MADE_1009875 01ad492c0d04c6559b65158df292786f 509 Pfam PF05683 Fumarase C-terminus 289 491 1.8E-83 T 13-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 MADE_1009875 01ad492c0d04c6559b65158df292786f 509 Pfam PF05681 Fumarate hydratase (Fumerase) 11 285 7.8E-99 T 13-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MADE_1009875 01ad492c0d04c6559b65158df292786f 509 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 285 2.5E-63 T 13-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 MADE_1009875 01ad492c0d04c6559b65158df292786f 509 Gene3D G3DSA:3.20.130.10 308 491 5.5E-59 T 13-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 MADE_1009875 01ad492c0d04c6559b65158df292786f 509 PIRSF PIRSF001394 1 507 1.3E-216 T 13-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 495 512 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 147 166 7.1E-52 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 481 495 7.1E-52 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 495 508 7.1E-52 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 336 357 7.1E-52 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 259 277 7.1E-52 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 463 481 7.1E-52 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 Gene3D G3DSA:3.40.50.10490 95 289 6.7E-220 T 13-10-2018 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 Pfam PF00342 Phosphoglucose isomerase 49 539 1.9E-207 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 263 276 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 Gene3D G3DSA:1.10.1390.10 505 546 6.9E-17 T 13-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 43 522 40.304 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 SUPERFAMILY SSF53697 4 545 5.0E-207 T 13-10-2018 MADE_1015455 4469a9c4910880d3f48c67a09eb9f493 549 Gene3D G3DSA:3.40.50.10490 10 504 6.7E-220 T 13-10-2018 MADE_1004895 0d7ffeea933707ad4c4d2384ef1533f3 518 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 351 511 1.1E-46 T 13-10-2018 IPR000160 GGDEF domain MADE_1004895 0d7ffeea933707ad4c4d2384ef1533f3 518 SUPERFAMILY SSF55073 358 511 2.35E-45 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1004895 0d7ffeea933707ad4c4d2384ef1533f3 518 Gene3D G3DSA:3.30.70.270 348 515 2.4E-53 T 13-10-2018 MADE_1004895 0d7ffeea933707ad4c4d2384ef1533f3 518 SMART SM00267 342 513 3.8E-50 T 13-10-2018 IPR000160 GGDEF domain MADE_1004895 0d7ffeea933707ad4c4d2384ef1533f3 518 Pfam PF00990 Diguanylate cyclase, GGDEF domain 354 508 2.2E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 137 149 1.5E-40 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 82 98 1.5E-40 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 60 76 1.5E-40 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.5E-40 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 106 125 1.5E-40 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 112 146 - T 13-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 SUPERFAMILY SSF53098 1 155 6.07E-55 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 152 47.911 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 Gene3D G3DSA:3.30.420.10 1 158 9.6E-52 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 149 3.2E-60 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_000001021170 952a3aa39d8cfcd2059a0ba99634a91d 172 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 1.8E-66 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 MADE_1015040 83cd55e8c2bf91dc44301a1f92142bd8 75 SUPERFAMILY SSF57716 2 52 2.42E-19 T 13-10-2018 MADE_1015040 83cd55e8c2bf91dc44301a1f92142bd8 75 Gene3D G3DSA:3.30.50.10 1 60 3.4E-22 T 13-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 MADE_1015040 83cd55e8c2bf91dc44301a1f92142bd8 75 Pfam PF03884 DNA gyrase inhibitor YacG 3 51 1.1E-23 T 13-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MADE_1015040 83cd55e8c2bf91dc44301a1f92142bd8 75 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 1 56 16.282 T 13-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 MADE_1019925 9093b640bc2074c157c63a2bd56a3cc0 184 Gene3D G3DSA:2.40.160.20 29 184 7.8E-8 T 13-10-2018 MADE_1019925 9093b640bc2074c157c63a2bd56a3cc0 184 SUPERFAMILY SSF56925 30 181 2.51E-10 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MADE_1019925 9093b640bc2074c157c63a2bd56a3cc0 184 Pfam PF13505 Outer membrane protein beta-barrel domain 10 171 2.3E-14 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel MADE_1003620 0f557f1c05f38ece55c90274363ef2d1 821 Pfam PF07715 TonB-dependent Receptor Plug Domain 118 221 6.5E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1003620 0f557f1c05f38ece55c90274363ef2d1 821 Pfam PF13620 Carboxypeptidase regulatory-like domain 23 82 5.1E-10 T 13-10-2018 MADE_1003620 0f557f1c05f38ece55c90274363ef2d1 821 SUPERFAMILY SSF49464 23 110 3.34E-12 T 13-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily MADE_1003620 0f557f1c05f38ece55c90274363ef2d1 821 Gene3D G3DSA:2.170.130.10 111 231 6.8E-28 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1003620 0f557f1c05f38ece55c90274363ef2d1 821 Gene3D G3DSA:2.60.40.1120 24 110 1.9E-9 T 13-10-2018 MADE_1003620 0f557f1c05f38ece55c90274363ef2d1 821 SUPERFAMILY SSF56935 103 819 5.13E-98 T 13-10-2018 MADE_1003620 0f557f1c05f38ece55c90274363ef2d1 821 Pfam PF00593 TonB dependent receptor 375 818 1.1E-40 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1006780 bea05b74952373b12c2000b80b0111c0 349 SUPERFAMILY SSF53300 84 265 2.82E-40 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1006780 bea05b74952373b12c2000b80b0111c0 349 Gene3D G3DSA:3.40.50.410 87 288 1.5E-55 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1006780 bea05b74952373b12c2000b80b0111c0 349 SMART SM00327 87 288 4.5E-19 T 13-10-2018 IPR002035 von Willebrand factor, type A MADE_1006780 bea05b74952373b12c2000b80b0111c0 349 Pfam PF00092 von Willebrand factor type A domain 90 282 5.3E-26 T 13-10-2018 IPR002035 von Willebrand factor, type A MADE_1001105 93f454ae378fc7063486a3e60fd4baa4 194 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 7 187 1.5E-49 T 13-10-2018 IPR010976 Beta-phosphoglucomutase hydrolase MADE_1001105 93f454ae378fc7063486a3e60fd4baa4 194 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 135 187 3.6E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1001105 93f454ae378fc7063486a3e60fd4baa4 194 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 187 1.5E-23 T 13-10-2018 MADE_1001105 93f454ae378fc7063486a3e60fd4baa4 194 SUPERFAMILY SSF56784 7 191 8.94E-46 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1001105 93f454ae378fc7063486a3e60fd4baa4 194 Gene3D G3DSA:1.10.150.240 20 90 5.1E-44 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MADE_1001105 93f454ae378fc7063486a3e60fd4baa4 194 Gene3D G3DSA:3.40.50.1000 8 189 5.1E-44 T 13-10-2018 IPR023214 HAD superfamily MADE_1018495 94a45ec3303fb26bbd1ce8adca1ca9c4 218 SUPERFAMILY SSF49503 62 145 7.89E-18 T 13-10-2018 IPR008972 Cupredoxin MADE_1018495 94a45ec3303fb26bbd1ce8adca1ca9c4 218 Gene3D G3DSA:2.60.40.420 50 145 1.3E-13 T 13-10-2018 IPR008972 Cupredoxin MADE_1018495 94a45ec3303fb26bbd1ce8adca1ca9c4 218 SUPERFAMILY SSF49452 131 199 7.26E-5 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 MADE_000001022900 dc7715f0422a67b45d780e38fbf67bb0 127 Gene3D G3DSA:3.30.1330.40 1 126 1.1E-39 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MADE_000001022900 dc7715f0422a67b45d780e38fbf67bb0 127 SUPERFAMILY SSF55298 1 126 5.03E-36 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MADE_000001022900 dc7715f0422a67b45d780e38fbf67bb0 127 Pfam PF01042 Endoribonuclease L-PSP 14 125 1.9E-31 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MADE_000001022900 dc7715f0422a67b45d780e38fbf67bb0 127 Hamap MF_00831 Putative aminoacrylate peracid reductase RutC [rutC]. 1 127 41.777 T 13-10-2018 IPR019898 Putative aminoacrylate peracid reductase RutC MADE_000001022900 dc7715f0422a67b45d780e38fbf67bb0 127 TIGRFAM TIGR03610 RutC: pyrimidine utilization protein C 1 127 6.7E-74 T 13-10-2018 IPR019898 Putative aminoacrylate peracid reductase RutC MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 Pfam PF00005 ABC transporter 22 191 2.7E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 Pfam PF12848 ABC transporter 230 304 2.2E-11 T 13-10-2018 IPR032781 ABC-transporter extension domain MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 Gene3D G3DSA:3.40.50.300 286 555 2.1E-75 T 13-10-2018 MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 Gene3D G3DSA:3.40.50.300 1 285 3.1E-84 T 13-10-2018 MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 Pfam PF00005 ABC transporter 340 473 1.6E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 9.6E-294 T 13-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 SMART SM00382 31 236 4.5E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 SMART SM00382 348 521 3.8E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 SUPERFAMILY SSF52540 12 243 9.52E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1012470 ffb52cdcb8c404d0790ce015ecbc4020 555 SUPERFAMILY SSF52540 303 528 2.83E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015365 bbc85cbc0fe6e6242f42d5958b6d4446 173 Gene3D G3DSA:2.60.40.3340 48 173 2.2E-39 T 13-10-2018 MADE_1015365 bbc85cbc0fe6e6242f42d5958b6d4446 173 Pfam PF14467 Domain of unknown function (DUF4426) 55 172 1.5E-44 T 13-10-2018 IPR025218 Domain of unknown function DUF4426 MADE_1019300 3e0098ebac5aa95e5925e9e92f19e6f2 537 Gene3D G3DSA:1.20.1250.20 1 237 3.1E-75 T 13-10-2018 MADE_1019300 3e0098ebac5aa95e5925e9e92f19e6f2 537 Gene3D G3DSA:1.20.1250.20 311 534 1.2E-60 T 13-10-2018 MADE_1019300 3e0098ebac5aa95e5925e9e92f19e6f2 537 SUPERFAMILY SSF103473 253 532 7.46E-19 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1019300 3e0098ebac5aa95e5925e9e92f19e6f2 537 Pfam PF07690 Major Facilitator Superfamily 34 493 9.7E-10 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1019300 3e0098ebac5aa95e5925e9e92f19e6f2 537 SUPERFAMILY SSF103473 1 270 1.13E-15 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1015010 39dbdedf5f6f91fc38135c95d8f229be 141 Gene3D G3DSA:3.30.700.10 12 140 3.3E-29 T 13-10-2018 MADE_1015010 39dbdedf5f6f91fc38135c95d8f229be 141 Pfam PF00114 Pilin (bacterial filament) 40 133 3.4E-9 T 13-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 MADE_1015010 39dbdedf5f6f91fc38135c95d8f229be 141 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1015010 39dbdedf5f6f91fc38135c95d8f229be 141 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 6.1E-11 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1015010 39dbdedf5f6f91fc38135c95d8f229be 141 SUPERFAMILY SSF54523 12 131 1.46E-21 T 13-10-2018 MADE_1015010 39dbdedf5f6f91fc38135c95d8f229be 141 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 32 1.4E-11 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001245 ddd0908151c6c12afff57036123bd286 570 Gene3D G3DSA:3.40.50.300 288 565 2.7E-104 T 13-10-2018 MADE_1001245 ddd0908151c6c12afff57036123bd286 570 Pfam PF00437 Type II/IV secretion system protein 191 453 9.8E-80 T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1001245 ddd0908151c6c12afff57036123bd286 570 SUPERFAMILY SSF52540 170 560 8.47E-96 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1001245 ddd0908151c6c12afff57036123bd286 570 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 42 146 8.4E-23 T 13-10-2018 IPR007831 General secretory system II, protein E, N-terminal MADE_1001245 ddd0908151c6c12afff57036123bd286 570 SUPERFAMILY SSF160246 2 145 3.66E-37 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily MADE_1001245 ddd0908151c6c12afff57036123bd286 570 Gene3D G3DSA:3.30.450.90 149 286 1.2E-43 T 13-10-2018 MADE_1001245 ddd0908151c6c12afff57036123bd286 570 Gene3D G3DSA:3.30.300.160 63 144 2.9E-5 T 13-10-2018 MADE_1001245 ddd0908151c6c12afff57036123bd286 570 SMART SM00382 314 461 2.1E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1001245 ddd0908151c6c12afff57036123bd286 570 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 381 395 - T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1014885 0a4b9a5b8cfc1fddfadf20236928a319 397 Pfam PF00589 Phage integrase family 211 370 5.9E-19 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1014885 0a4b9a5b8cfc1fddfadf20236928a319 397 Pfam PF12167 Arm DNA-binding domain 11 79 4.1E-18 T 13-10-2018 IPR022000 Min27-like integrase, DNA-binding domain MADE_1014885 0a4b9a5b8cfc1fddfadf20236928a319 397 Gene3D G3DSA:1.10.443.10 191 386 8.2E-38 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1014885 0a4b9a5b8cfc1fddfadf20236928a319 397 SUPERFAMILY SSF56349 94 377 1.98E-52 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1014885 0a4b9a5b8cfc1fddfadf20236928a319 397 Gene3D G3DSA:1.10.150.130 95 190 9.6E-12 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1014885 0a4b9a5b8cfc1fddfadf20236928a319 397 Pfam PF13102 Phage integrase SAM-like domain 96 183 1.3E-6 T 13-10-2018 IPR025269 Phage integrase SAM-like domain MADE_000001022045 1211de69e1684807787fe2bd68305e43 523 Gene3D G3DSA:1.20.1530.20 3 364 1.3E-46 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily MADE_000001022045 1211de69e1684807787fe2bd68305e43 523 Pfam PF00999 Sodium/hydrogen exchanger family 6 347 1.5E-39 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MADE_000001022045 1211de69e1684807787fe2bd68305e43 523 SUPERFAMILY SSF51735 387 512 1.09E-17 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001022045 1211de69e1684807787fe2bd68305e43 523 Gene3D G3DSA:3.40.50.720 381 520 6.0E-28 T 13-10-2018 MADE_000001022045 1211de69e1684807787fe2bd68305e43 523 Pfam PF02254 TrkA-N domain 387 502 5.5E-19 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 715 0.0 T 13-10-2018 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-7292|MetaCyc: PWY-7307|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 SUPERFAMILY SSF51735 318 496 1.35E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 13-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 Gene3D G3DSA:1.10.1040.50 498 710 8.0E-71 T 13-10-2018 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 628 694 3.3E-5 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 497 593 4.5E-23 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 Gene3D G3DSA:3.40.50.720 315 497 8.6E-65 T 13-10-2018 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 220 8.5E-37 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 494 518 - T 13-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 SUPERFAMILY SSF48179 625 715 3.57E-24 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 Gene3D G3DSA:3.90.226.10 1 312 3.3E-95 T 13-10-2018 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 SUPERFAMILY SSF52096 2 303 1.71E-69 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 318 495 1.9E-59 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 MADE_1003310 52e7cc51c6c4c081f47dfe21a25e92e9 716 SUPERFAMILY SSF48179 496 617 7.65E-27 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 SUPERFAMILY SSF55073 243 392 2.67E-17 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 Gene3D G3DSA:3.30.1040.50 103 151 6.7E-12 T 13-10-2018 MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 Pfam PF00990 Diguanylate cyclase, GGDEF domain 239 389 1.7E-20 T 13-10-2018 IPR000160 GGDEF domain MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 236 390 2.1E-13 T 13-10-2018 IPR000160 GGDEF domain MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 SMART SM00052 404 645 1.3E-22 T 13-10-2018 IPR001633 EAL domain MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 SMART SM00267 227 396 2.8E-9 T 13-10-2018 IPR000160 GGDEF domain MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 Gene3D G3DSA:3.30.70.270 221 395 1.3E-27 T 13-10-2018 MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 Gene3D G3DSA:3.20.20.450 402 641 1.7E-49 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 SUPERFAMILY SSF141868 410 641 1.57E-47 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 Pfam PF00563 EAL domain 411 640 7.0E-47 T 13-10-2018 IPR001633 EAL domain MADE_1008150 0e9ef23a37b075e6af342c65f1fa07fb 645 Pfam PF16448 LapD/MoxY periplasmic domain 23 147 7.2E-41 T 13-10-2018 IPR032244 LapD/MoxY, periplasmic domain MADE_000001023485 fd1398cf82d3868871419539a3c8c427 202 Gene3D G3DSA:3.40.30.10 1 86 3.9E-25 T 13-10-2018 MADE_000001023485 fd1398cf82d3868871419539a3c8c427 202 SUPERFAMILY SSF52833 1 90 1.04E-22 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_000001023485 fd1398cf82d3868871419539a3c8c427 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 81 1.1E-18 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_000001023485 fd1398cf82d3868871419539a3c8c427 202 SUPERFAMILY SSF47616 78 199 3.9E-24 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_000001023485 fd1398cf82d3868871419539a3c8c427 202 Gene3D G3DSA:1.20.1050.10 87 197 2.4E-39 T 13-10-2018 MADE_000001023485 fd1398cf82d3868871419539a3c8c427 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 138 197 4.5E-10 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal MADE_000001023525 3a7f7fd45f30990ba5f1e5af73ccfaa1 359 Gene3D G3DSA:3.40.50.1400 179 317 3.4E-97 T 13-10-2018 MADE_000001023525 3a7f7fd45f30990ba5f1e5af73ccfaa1 359 Gene3D G3DSA:3.40.50.1400 18 336 3.4E-97 T 13-10-2018 MADE_000001023525 3a7f7fd45f30990ba5f1e5af73ccfaa1 359 Hamap MF_00323 Ferrochelatase [hemH]. 15 336 38.136 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MADE_000001023525 3a7f7fd45f30990ba5f1e5af73ccfaa1 359 TIGRFAM TIGR00109 hemH: ferrochelatase 14 336 7.7E-103 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MADE_000001023525 3a7f7fd45f30990ba5f1e5af73ccfaa1 359 SUPERFAMILY SSF53800 15 341 6.87E-112 T 13-10-2018 MADE_000001023525 3a7f7fd45f30990ba5f1e5af73ccfaa1 359 Pfam PF00762 Ferrochelatase 16 335 4.7E-115 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 SMART SM00490 460 546 8.8E-20 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 SUPERFAMILY SSF52540 5 415 1.24E-138 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Gene3D G3DSA:4.10.860.10 626 671 1.8E-12 T 13-10-2018 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Pfam PF12344 Ultra-violet resistance protein B 552 593 7.6E-20 T 13-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 SUPERFAMILY SSF46600 625 667 2.35E-10 T 13-10-2018 IPR036876 UVR domain superfamily MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Gene3D G3DSA:3.40.50.300 1 243 1.3E-77 T 13-10-2018 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Gene3D G3DSA:3.40.50.300 270 414 7.6E-52 T 13-10-2018 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 SMART SM00487 9 425 6.5E-26 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Pfam PF02151 UvrB/uvrC motif 633 666 2.6E-9 T 13-10-2018 IPR001943 UVR domain GO:0005515 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 664 0.0 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Gene3D G3DSA:3.40.50.300 415 596 2.9E-50 T 13-10-2018 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Pfam PF04851 Type III restriction enzyme, res subunit 13 121 3.6E-9 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Pfam PF00271 Helicase conserved C-terminal domain 437 544 9.9E-18 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 SUPERFAMILY SSF52540 37 583 6.31E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006670 ccd8eae4d9188dc18cd273ba450cfa75 671 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 666 43.71 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 MADE_1009995 c7c9d4fecc788a0c269f4a6e4d710369 589 Gene3D G3DSA:3.30.479.30 71 190 4.9E-24 T 13-10-2018 MADE_1009995 c7c9d4fecc788a0c269f4a6e4d710369 589 Pfam PF15975 Flotillin 418 540 2.0E-34 T 13-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 MADE_1009995 c7c9d4fecc788a0c269f4a6e4d710369 589 SMART SM00244 31 200 9.3E-4 T 13-10-2018 IPR001107 Band 7 domain MADE_1009995 c7c9d4fecc788a0c269f4a6e4d710369 589 Pfam PF01145 SPFH domain / Band 7 family 44 217 7.9E-18 T 13-10-2018 IPR001107 Band 7 domain MADE_1009995 c7c9d4fecc788a0c269f4a6e4d710369 589 SUPERFAMILY SSF117892 62 203 5.23E-21 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily MADE_1007395 456606eed021e83d7806225ac62e88ee 749 SUPERFAMILY SSF47203 290 445 2.9E-23 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 Gene3D G3DSA:2.40.110.10 166 289 1.2E-90 T 13-10-2018 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 Pfam PF09317 Domain of unknown function (DUF1974) 444 726 6.9E-79 T 13-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 Gene3D G3DSA:1.10.540.10 53 165 1.2E-90 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 290 433 4.7E-13 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 71 162 2.7E-13 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 167 267 1.5E-10 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 SUPERFAMILY SSF56645 50 285 7.46E-46 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1007395 456606eed021e83d7806225ac62e88ee 749 Gene3D G3DSA:1.20.140.10 290 435 1.2E-90 T 13-10-2018 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Gene3D G3DSA:3.40.50.300 6 595 3.3E-246 T 13-10-2018 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 925 0.0 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Gene3D G3DSA:3.40.50.300 617 936 1.3E-142 T 13-10-2018 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 940 22.83 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 SUPERFAMILY SSF52540 621 911 2.49E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Gene3D G3DSA:1.10.8.280 287 403 3.3E-246 T 13-10-2018 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Gene3D G3DSA:1.20.1580.10 692 830 1.3E-142 T 13-10-2018 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Gene3D G3DSA:3.30.190.20 130 239 3.3E-246 T 13-10-2018 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Pfam PF00005 ABC transporter 623 860 8.8E-10 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 Gene3D G3DSA:1.20.1580.10 90 492 3.3E-246 T 13-10-2018 MADE_1001095 0cc9928ce50ff8efbd59667b92ea9db4 943 SUPERFAMILY SSF52540 3 569 7.2E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 Pfam PF03237 Terminase-like family 493 712 5.5E-14 T 13-10-2018 IPR004921 Terminase large subunit, T4likevirus-type MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 SUPERFAMILY SSF55608 344 418 4.99E-15 T 13-10-2018 IPR027434 Homing endonuclease MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 Gene3D G3DSA:3.30.420.240 708 879 1.8E-6 T 13-10-2018 MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 Pfam PF17289 Terminase RNaseH-like domain 728 877 1.6E-12 T 13-10-2018 IPR035421 Terminase, large subunit gp17-like MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 740 876 1.9E-16 T 13-10-2018 IPR006517 Archaeophage PsiM2, terminase large subunit MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 Pfam PF14528 LAGLIDADG-like domain 362 410 7.6E-6 T 13-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 SUPERFAMILY SSF51294 150 274 1.96E-8 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MADE_1014625 5f52234e01b9ed23cbfabe7a0c85b53c 915 Gene3D G3DSA:3.10.28.10 243 455 6.5E-44 T 13-10-2018 IPR027434 Homing endonuclease MADE_1008335 f95483418b6e34262127e0500bfa47de 187 Gene3D G3DSA:3.40.50.2020 1 184 2.5E-35 T 13-10-2018 MADE_1008335 f95483418b6e34262127e0500bfa47de 187 Pfam PF00156 Phosphoribosyl transferase domain 9 161 2.2E-13 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MADE_1008335 f95483418b6e34262127e0500bfa47de 187 SUPERFAMILY SSF53271 3 162 7.1E-28 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like MADE_1018290 92539ee8756a2840763aeaf01288f37b 174 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 171 2.2E-85 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MADE_1018290 92539ee8756a2840763aeaf01288f37b 174 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 41.162 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MADE_1018290 92539ee8756a2840763aeaf01288f37b 174 Gene3D G3DSA:3.60.20.10 1 173 2.6E-66 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1018290 92539ee8756a2840763aeaf01288f37b 174 Pfam PF00227 Proteasome subunit 2 169 8.1E-24 T 13-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 MADE_1018290 92539ee8756a2840763aeaf01288f37b 174 PIRSF PIRSF039093 1 174 8.4E-86 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 MADE_1018290 92539ee8756a2840763aeaf01288f37b 174 SUPERFAMILY SSF56235 2 172 2.85E-57 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1015165 5e03ee4c2d6f96278985463deba1625b 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015165 5e03ee4c2d6f96278985463deba1625b 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 9.4E-6 T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015165 5e03ee4c2d6f96278985463deba1625b 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 25.341 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015165 5e03ee4c2d6f96278985463deba1625b 360 Pfam PF00953 Glycosyl transferase family 4 99 283 3.5E-37 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MADE_1015165 5e03ee4c2d6f96278985463deba1625b 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 360 3.3E-146 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015165 5e03ee4c2d6f96278985463deba1625b 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 Pfam PF03466 LysR substrate binding domain 91 292 7.2E-40 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 Gene3D G3DSA:1.10.10.10 1 86 4.2E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 SUPERFAMILY SSF53850 92 321 5.67E-43 T 13-10-2018 MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 Gene3D G3DSA:3.40.190.10 167 267 4.6E-99 T 13-10-2018 MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 SUPERFAMILY SSF46785 1 86 6.03E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 4.0E-14 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009855 a2321562c8c6067a95dd8d0dd4640d00 324 Gene3D G3DSA:3.40.190.10 92 303 4.6E-99 T 13-10-2018 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 PRINTS PR00151 Porphobilinogen deaminase signature 49 69 2.2E-50 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 PRINTS PR00151 Porphobilinogen deaminase signature 147 164 2.2E-50 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 PRINTS PR00151 Porphobilinogen deaminase signature 234 251 2.2E-50 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 PRINTS PR00151 Porphobilinogen deaminase signature 80 99 2.2E-50 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 PRINTS PR00151 Porphobilinogen deaminase signature 128 145 2.2E-50 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 9 301 39.467 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 10 301 4.9E-114 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 230 299 1.2E-20 T 13-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 SUPERFAMILY SSF54782 224 311 1.7E-27 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 SUPERFAMILY SSF53850 8 222 3.15E-86 T 13-10-2018 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 10 216 5.1E-79 T 13-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 Gene3D G3DSA:3.40.190.10 107 206 1.3E-84 T 13-10-2018 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 PIRSF PIRSF001438 1 312 4.5E-123 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 Gene3D G3DSA:3.30.160.40 225 310 1.1E-28 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 235 251 - T 13-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 MADE_1000740 80ec293a14a8f08568288cd055b74acc 312 Gene3D G3DSA:3.40.190.10 10 214 1.3E-84 T 13-10-2018 MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 Pfam PF01455 HupF/HypC family 1 67 1.5E-25 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 73 3.4E-26 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 Gene3D G3DSA:2.40.50.970 1 74 1.5E-25 T 13-10-2018 IPR037254 HupF/HypC superfamily MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 13-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 58 70 4.8E-16 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 4.8E-16 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 4.8E-16 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 4.8E-16 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC MADE_1001685 e0c01c159b54f08d3dc1d8cc6602911b 75 SUPERFAMILY SSF159127 1 72 2.35E-24 T 13-10-2018 IPR037254 HupF/HypC superfamily MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 Pfam PF13353 4Fe-4S single cluster domain 18 120 2.2E-8 T 13-10-2018 MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 Pfam PF04055 Radical SAM superfamily 16 175 5.4E-24 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 SMART SM00729 11 216 1.4E-4 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 Pfam PF06463 Molybdenum Cofactor Synthesis C 181 305 8.7E-33 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 Gene3D G3DSA:3.20.20.70 1 322 5.5E-78 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 2 322 7.2E-98 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 SUPERFAMILY SSF102114 4 272 7.59E-68 T 13-10-2018 MADE_1007315 cafd18d48e59bd7230e50891d7ff1684 322 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 Gene3D G3DSA:1.25.40.10 128 271 6.7E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 SUPERFAMILY SSF81901 69 197 2.88E-12 T 13-10-2018 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 Gene3D G3DSA:1.25.40.10 38 127 3.3E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 SUPERFAMILY SSF48452 310 430 2.15E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 SMART SM00028 381 414 90.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 SMART SM00028 95 128 0.046 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 SMART SM00028 133 166 100.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 SMART SM00028 345 378 500.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 Pfam PF13432 Tetratricopeptide repeat 350 408 2.2E-4 T 13-10-2018 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 Pfam PF13181 Tetratricopeptide repeat 97 126 0.063 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1003900 223ac6df59d86dcd1b9b597651e0ba64 441 Gene3D G3DSA:1.25.40.10 274 412 1.6E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 48 154 4.0E-16 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 SUPERFAMILY SSF52540 5 235 1.49E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 Gene3D G3DSA:1.20.272.10 232 335 1.3E-41 T 13-10-2018 MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 SUPERFAMILY SSF48019 242 423 1.25E-70 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 Gene3D G3DSA:1.10.8.60 160 231 2.2E-14 T 13-10-2018 MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 Pfam PF16193 AAA C-terminal domain 184 257 3.5E-23 T 13-10-2018 IPR032423 AAA C-terminal domain MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 Pfam PF12002 MgsA AAA+ ATPase C terminal 258 421 3.3E-63 T 13-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 Gene3D G3DSA:3.40.50.300 1 159 2.0E-45 T 13-10-2018 MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 SMART SM00382 44 160 6.2E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1010705 0ed056a1a7df73b97e2fcad474108674 435 Gene3D G3DSA:1.10.3710.10 336 435 1.4E-35 T 13-10-2018 MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 SUPERFAMILY SSF52540 343 589 1.23E-89 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 Gene3D G3DSA:1.20.1560.10 22 344 5.9E-108 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 SUPERFAMILY SSF90123 15 340 1.09E-59 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 SMART SM00382 379 559 1.1E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 Gene3D G3DSA:3.40.50.300 345 601 4.7E-95 T 13-10-2018 MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 Pfam PF00664 ABC transporter transmembrane region 33 308 2.7E-40 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_1007310 5f2db15a6223995c75139a98cc8de000 602 Pfam PF00005 ABC transporter 370 519 1.9E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1013245 12dbd4b97b774f1af03c9a22bb6705dd 131 Pfam PF01124 MAPEG family 6 124 1.0E-26 T 13-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein MADE_1013245 12dbd4b97b774f1af03c9a22bb6705dd 131 Gene3D G3DSA:1.20.120.550 3 130 2.3E-27 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MADE_1013245 12dbd4b97b774f1af03c9a22bb6705dd 131 SUPERFAMILY SSF161084 3 127 9.16E-29 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MADE_1012350 2a9e8f42f29096245fb8da884408c289 254 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 4 247 38.547 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD MADE_1012350 2a9e8f42f29096245fb8da884408c289 254 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 8 252 3.7E-90 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD MADE_1012350 2a9e8f42f29096245fb8da884408c289 254 SUPERFAMILY SSF48452 37 122 2.72E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1012350 2a9e8f42f29096245fb8da884408c289 254 Gene3D G3DSA:1.25.40.10 36 253 1.8E-61 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1012350 2a9e8f42f29096245fb8da884408c289 254 Pfam PF13525 Outer membrane lipoprotein 35 239 4.4E-77 T 13-10-2018 IPR039565 Outer membrane lipoprotein BamD-like MADE_1011835 f78e3065701a35d6f625fe7e0ad87acb 223 Pfam PF00881 Nitroreductase family 8 197 5.7E-29 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MADE_1011835 f78e3065701a35d6f625fe7e0ad87acb 223 Gene3D G3DSA:3.40.109.10 1 222 4.0E-52 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_1011835 f78e3065701a35d6f625fe7e0ad87acb 223 SUPERFAMILY SSF55469 1 220 3.53E-40 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 Pfam PF02541 Ppx/GppA phosphatase family 32 315 1.9E-82 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 Gene3D G3DSA:1.10.3210.10 318 517 1.4E-63 T 13-10-2018 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 Gene3D G3DSA:3.30.420.40 20 311 1.1E-89 T 13-10-2018 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 SUPERFAMILY SSF109604 321 509 1.57E-48 T 13-10-2018 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 PIRSF PIRSF001267 10 510 5.6E-185 T 13-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 Gene3D G3DSA:3.30.420.150 123 303 1.1E-89 T 13-10-2018 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 19 314 2.4E-100 T 13-10-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 SUPERFAMILY SSF53067 143 319 1.76E-46 T 13-10-2018 MADE_1004375 6aab821c8b673179cb24cb364ba8a115 520 SUPERFAMILY SSF53067 19 138 1.38E-36 T 13-10-2018 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 SUPERFAMILY SSF47384 233 315 6.08E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 11 466 3.2E-135 T 13-10-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 315 6.0E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 SMART SM00304 195 248 0.0096 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 Gene3D G3DSA:1.10.287.130 199 315 1.2E-22 T 13-10-2018 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 SMART SM00388 249 315 2.8E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 SMART SM00387 359 468 7.7E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 3.5E-6 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 3.5E-6 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 424 3.5E-6 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 461 1.2E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 SUPERFAMILY SSF55874 304 465 1.7E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1001530 343120c6aa6f84b53f4d17ec6310824a 468 Gene3D G3DSA:3.30.565.10 321 468 8.2E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015335 0671f5c0027131634f7b66b0cb976ed4 108 Pfam PF09413 Putative prokaryotic signal transducing protein 2 67 1.1E-10 T 13-10-2018 IPR018551 Domain of unknown function DUF2007 MADE_1015335 0671f5c0027131634f7b66b0cb976ed4 108 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 82 101 - T 13-10-2018 IPR001876 Zinc finger, RanBP2-type MADE_000001022385 ce3d81f26f9ab9a80903566e6e85d7ab 427 SUPERFAMILY SSF53474 67 381 5.78E-6 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001022385 ce3d81f26f9ab9a80903566e6e85d7ab 427 Pfam PF03283 Pectinacetylesterase 68 243 1.2E-17 T 13-10-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 Pfam PF00326 Prolyl oligopeptidase family 508 720 1.2E-64 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 SUPERFAMILY SSF53474 460 700 1.53E-38 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 517 541 1.5E-46 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 491 509 1.5E-46 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 545 564 1.5E-46 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 575 595 1.5E-46 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 633 648 1.5E-46 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 651 673 1.5E-46 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 SUPERFAMILY SSF50993 44 449 5.49E-86 T 13-10-2018 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 Gene3D G3DSA:3.40.50.1820 64 717 1.0E-244 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 Gene3D G3DSA:2.130.10.120 115 448 1.0E-244 T 13-10-2018 MADE_1012155 e489d102aabd5a8252fee7a52c496c90 725 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 49 446 4.8E-98 T 13-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MADE_1003425 4724547c28a519242ea25b617dc194f9 501 Pfam PF01928 CYTH domain 1 201 6.3E-25 T 13-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MADE_1003425 4724547c28a519242ea25b617dc194f9 501 SUPERFAMILY SSF55154 1 224 2.29E-40 T 13-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 MADE_1003425 4724547c28a519242ea25b617dc194f9 501 SMART SM01118 1 207 3.7E-26 T 13-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 MADE_1003425 4724547c28a519242ea25b617dc194f9 501 Gene3D G3DSA:2.40.320.10 1 203 1.5E-28 T 13-10-2018 MADE_1016955 cb318b37186d5fa33a8256a49b9835c0 297 SMART SM00563 89 231 4.0E-14 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1016955 cb318b37186d5fa33a8256a49b9835c0 297 Pfam PF01553 Acyltransferase 79 227 2.0E-14 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1016955 cb318b37186d5fa33a8256a49b9835c0 297 SUPERFAMILY SSF69593 57 291 1.02E-27 T 13-10-2018 MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 3 338 5.4E-156 T 13-10-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 Gene3D G3DSA:3.90.180.10 26 334 1.8E-97 T 13-10-2018 MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 151 172 - T 13-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 SUPERFAMILY SSF50129 13 145 5.19E-32 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 Gene3D G3DSA:3.40.50.720 129 276 1.8E-97 T 13-10-2018 MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 Pfam PF13602 Zinc-binding dehydrogenase 195 335 2.1E-20 T 13-10-2018 MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 SMART SM00829 18 335 1.4E-9 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 SUPERFAMILY SSF51735 118 287 4.65E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009960 a5a592bc5d13691f6fb457b713f29f1e 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 90 6.1E-8 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 PRINTS PR00412 Epoxide hydrolase signature 73 88 3.4E-14 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 PRINTS PR00412 Epoxide hydrolase signature 53 71 3.4E-14 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 PRINTS PR00412 Epoxide hydrolase signature 119 132 3.4E-14 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 PRINTS PR00412 Epoxide hydrolase signature 275 297 3.4E-14 T 13-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 Pfam PF12697 Alpha/beta hydrolase family 49 292 6.1E-15 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 Gene3D G3DSA:3.40.50.1820 1 300 1.6E-75 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 SUPERFAMILY SSF53474 17 300 6.23E-49 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 73 88 9.6E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 9.6E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1008775 907d2efa74e0fe21d16a9ae11b4ffde8 306 PRINTS PR00111 Alpha/beta hydrolase fold signature 119 132 9.6E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1002560 7be5633827d6f64af817ba636817a356 355 Gene3D G3DSA:1.20.1090.10 171 355 2.4E-67 T 13-10-2018 MADE_1002560 7be5633827d6f64af817ba636817a356 355 Gene3D G3DSA:3.40.50.1970 1 170 1.6E-63 T 13-10-2018 MADE_1002560 7be5633827d6f64af817ba636817a356 355 Pfam PF01761 3-dehydroquinate synthase 65 323 1.1E-107 T 13-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MADE_1002560 7be5633827d6f64af817ba636817a356 355 PIRSF PIRSF001455 8 353 4.1E-106 T 13-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MADE_1002560 7be5633827d6f64af817ba636817a356 355 SUPERFAMILY SSF56796 4 354 5.89E-114 T 13-10-2018 MADE_1002560 7be5633827d6f64af817ba636817a356 355 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 349 1.3E-116 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MADE_1002560 7be5633827d6f64af817ba636817a356 355 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 354 70.874 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 MADE_1014270 8c2c2721e2757cf8308624e8c3f36e81 232 Pfam PF01730 UreF 44 189 2.8E-33 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MADE_1014270 8c2c2721e2757cf8308624e8c3f36e81 232 Hamap MF_01385 Urease accessory protein UreF [ureF]. 11 232 28.922 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MADE_1014270 8c2c2721e2757cf8308624e8c3f36e81 232 PIRSF PIRSF009467 8 232 9.0E-55 T 13-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 MADE_1014270 8c2c2721e2757cf8308624e8c3f36e81 232 Gene3D G3DSA:1.10.4190.10 9 210 3.6E-49 T 13-10-2018 IPR038277 UreF domain superfamily MADE_1015805 3f7c610561f8a939cf8edcfc08777aca 233 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 3 231 42.878 T 13-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MADE_1015805 3f7c610561f8a939cf8edcfc08777aca 233 Pfam PF01048 Phosphorylase superfamily 3 228 3.7E-49 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MADE_1015805 3f7c610561f8a939cf8edcfc08777aca 233 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 230 8.2E-80 T 13-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 MADE_1015805 3f7c610561f8a939cf8edcfc08777aca 233 Gene3D G3DSA:3.40.50.1580 1 233 1.2E-67 T 13-10-2018 MADE_1015805 3f7c610561f8a939cf8edcfc08777aca 233 SUPERFAMILY SSF53167 3 231 1.7E-69 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MADE_1020160 114017f39e54fc9037d2feed6407cbaf 612 Gene3D G3DSA:3.10.20.310 127 214 5.3E-15 T 13-10-2018 MADE_1020160 114017f39e54fc9037d2feed6407cbaf 612 Pfam PF01103 Surface antigen 303 597 4.7E-37 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 MADE_1020160 114017f39e54fc9037d2feed6407cbaf 612 Gene3D G3DSA:2.40.160.50 292 612 8.4E-91 T 13-10-2018 MADE_1020160 114017f39e54fc9037d2feed6407cbaf 612 Gene3D G3DSA:3.10.20.310 215 291 1.5E-16 T 13-10-2018 MADE_1020160 114017f39e54fc9037d2feed6407cbaf 612 Pfam PF17243 POTRA domain TamA domain 1 54 124 6.7E-12 T 13-10-2018 IPR035243 TamA, POTRA domain 1 MADE_1020160 114017f39e54fc9037d2feed6407cbaf 612 Gene3D G3DSA:3.10.20.310 51 126 1.4E-7 T 13-10-2018 MADE_1007125 67739a682c283a827cabe3e61f565180 712 Pfam PF01515 Phosphate acetyl/butaryl transferase 394 706 3.8E-121 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MADE_1007125 67739a682c283a827cabe3e61f565180 712 Pfam PF13500 AAA domain 3 229 8.7E-33 T 13-10-2018 MADE_1007125 67739a682c283a827cabe3e61f565180 712 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 406 706 6.3E-127 T 13-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MADE_1007125 67739a682c283a827cabe3e61f565180 712 SUPERFAMILY SSF75138 229 352 8.44E-24 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MADE_1007125 67739a682c283a827cabe3e61f565180 712 Gene3D G3DSA:3.40.50.300 3 225 4.6E-14 T 13-10-2018 MADE_1007125 67739a682c283a827cabe3e61f565180 712 SUPERFAMILY SSF52540 1 240 1.12E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007125 67739a682c283a827cabe3e61f565180 712 PIRSF PIRSF006107 1 712 0.0 T 13-10-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MADE_1007125 67739a682c283a827cabe3e61f565180 712 Gene3D G3DSA:3.40.50.10950 397 709 8.6E-132 T 13-10-2018 MADE_1007125 67739a682c283a827cabe3e61f565180 712 Gene3D G3DSA:3.40.50.10750 529 682 8.6E-132 T 13-10-2018 MADE_1007125 67739a682c283a827cabe3e61f565180 712 Pfam PF07085 DRTGG domain 233 344 2.3E-28 T 13-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 MADE_1007125 67739a682c283a827cabe3e61f565180 712 Gene3D G3DSA:3.40.1390.20 226 363 3.4E-19 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily MADE_1007125 67739a682c283a827cabe3e61f565180 712 SUPERFAMILY SSF53659 394 709 1.4E-92 T 13-10-2018 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 SUPERFAMILY SSF55120 7 352 4.89E-91 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 199 350 3.8E-22 T 13-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 11 173 9.3E-40 T 13-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 79 92 - T 13-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 Gene3D G3DSA:3.30.2340.10 179 316 2.5E-112 T 13-10-2018 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 10 247 2.4E-59 T 13-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 Gene3D G3DSA:3.30.2350.20 19 350 2.5E-112 T 13-10-2018 MADE_1003375 5a21410437f4fbb09ed240924b128976 361 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 7 356 25.78 T 13-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1009705 702b3e709c611cd34239dcfb6c4dcde0 153 Pfam PF06127 Protein of unknown function (DUF962) 1 148 1.9E-19 T 13-10-2018 IPR009305 Protein of unknown function DUF962 MADE_1003690 ffb48d791c2b97989a486f99d6baee95 521 Pfam PF01740 STAS domain 418 505 1.3E-10 T 13-10-2018 IPR002645 STAS domain MADE_1003690 ffb48d791c2b97989a486f99d6baee95 521 Pfam PF00916 Sulfate permease family 13 376 6.4E-54 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MADE_1003690 ffb48d791c2b97989a486f99d6baee95 521 SUPERFAMILY SSF52091 417 500 4.91E-14 T 13-10-2018 IPR036513 STAS domain superfamily MADE_1003690 ffb48d791c2b97989a486f99d6baee95 521 Gene3D G3DSA:3.30.750.24 409 501 1.4E-28 T 13-10-2018 IPR036513 STAS domain superfamily MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 Gene3D G3DSA:1.10.230.10 267 375 1.0E-145 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 Pfam PF00285 Citrate synthase, C-terminal domain 45 410 1.8E-131 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 13 421 1.5E-227 T 13-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 Gene3D G3DSA:2.20.28.60 1 49 1.8E-22 T 13-10-2018 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 ProSitePatterns PS00480 Citrate synthase signature. 302 314 - T 13-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 SUPERFAMILY SSF48256 5 424 3.01E-163 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 Gene3D G3DSA:1.10.580.10 56 410 1.0E-145 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 PRINTS PR00143 Citrate synthase signature 295 315 1.6E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 PRINTS PR00143 Citrate synthase signature 378 392 1.6E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 PRINTS PR00143 Citrate synthase signature 358 374 1.6E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 PRINTS PR00143 Citrate synthase signature 240 268 1.6E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 PRINTS PR00143 Citrate synthase signature 164 177 1.6E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 PRINTS PR00143 Citrate synthase signature 218 233 1.6E-54 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1009470 21037d3611ecd84f57b4b09e72bfa328 425 PIRSF PIRSF001369 37 425 2.9E-167 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 Gene3D G3DSA:1.10.10.1600 432 509 2.9E-34 T 13-10-2018 MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 SUPERFAMILY SSF89550 5 262 1.0E-15 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 290 730 6.5E-181 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 Gene3D G3DSA:2.40.50.140 982 1068 1.2E-5 T 13-10-2018 MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 Pfam PF14579 Helix-hairpin-helix motif 803 892 3.9E-26 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1025 0.0 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 Pfam PF02811 PHP domain 7 170 3.8E-43 T 13-10-2018 IPR004013 PHP domain GO:0003824 MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 SMART SM00481 6 73 2.5E-23 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal MADE_1005390 26d25fa9ccc8db0fe47b265d054e0bed 1154 Gene3D G3DSA:3.20.20.140 1 269 1.0E-89 T 13-10-2018 MADE_000001021825 1974f8b8bdaee4b71cd9b5227aa22a11 105 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 6.8E-38 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MADE_000001021825 1974f8b8bdaee4b71cd9b5227aa22a11 105 Pfam PF02410 Ribosomal silencing factor during starvation 13 104 2.3E-26 T 13-10-2018 MADE_000001021825 1974f8b8bdaee4b71cd9b5227aa22a11 105 SUPERFAMILY SSF81301 2 105 7.19E-38 T 13-10-2018 MADE_000001021825 1974f8b8bdaee4b71cd9b5227aa22a11 105 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.655 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS MADE_000001021825 1974f8b8bdaee4b71cd9b5227aa22a11 105 Gene3D G3DSA:3.30.460.10 1 105 3.5E-37 T 13-10-2018 MADE_1004730 eaf0d494ed8c1fb0a890a08b75994dad 179 Pfam PF02464 Competence-damaged protein 27 175 2.8E-53 T 13-10-2018 IPR008136 CinA, C-terminal MADE_1004730 eaf0d494ed8c1fb0a890a08b75994dad 179 Gene3D G3DSA:3.90.950.20 10 177 6.2E-55 T 13-10-2018 IPR036653 CinA-like, C-terminal MADE_1004730 eaf0d494ed8c1fb0a890a08b75994dad 179 SUPERFAMILY SSF142433 25 176 6.67E-51 T 13-10-2018 IPR036653 CinA-like, C-terminal MADE_1004730 eaf0d494ed8c1fb0a890a08b75994dad 179 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 29 174 7.5E-46 T 13-10-2018 IPR008136 CinA, C-terminal MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 2.4E-14 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 180 200 2.4E-14 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 290 301 2.4E-14 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 SUPERFAMILY SSF53223 4 140 6.72E-41 T 13-10-2018 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 222 331 8.5E-13 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 133 5.6E-26 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 Gene3D G3DSA:3.40.50.720 134 341 1.1E-134 T 13-10-2018 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 Gene3D G3DSA:3.40.50.10860 11 348 1.1E-134 T 13-10-2018 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 SMART SM00839 149 352 2.8E-72 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 13-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 PIRSF PIRSF000188 1 352 4.6E-140 T 13-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 MADE_1006200 5a260162ef1dfc13a9389f07663fcbd5 352 SUPERFAMILY SSF51735 150 348 5.16E-52 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 TIGRFAM TIGR01391 dnaG: DNA primase 5 421 2.4E-148 T 13-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Hamap MF_00974 DNA primase [dnaG]. 4 587 28.813 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 SMART SM00400 36 90 3.9E-38 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Pfam PF01807 CHC2 zinc finger 6 101 5.7E-41 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Gene3D G3DSA:3.90.580.10 1 101 9.2E-39 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 254 1.8E-43 T 13-10-2018 IPR013264 DNA primase, catalytic core, N-terminal MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Gene3D G3DSA:3.90.980.10 118 243 6.2E-47 T 13-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Pfam PF13662 Toprim domain 262 340 1.5E-13 T 13-10-2018 IPR006171 TOPRIM domain MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Pfam PF08278 DNA primase DnaG DnaB-binding 461 585 5.2E-27 T 13-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 SUPERFAMILY SSF56731 119 428 3.27E-108 T 13-10-2018 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 SUPERFAMILY SSF57783 5 101 4.59E-37 T 13-10-2018 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 SUPERFAMILY SSF117023 456 589 4.84E-32 T 13-10-2018 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 SMART SM00493 262 333 3.2E-20 T 13-10-2018 IPR006171 TOPRIM domain MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Gene3D G3DSA:1.10.860.10 444 592 6.1E-31 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 PIRSF PIRSF002811 2 592 3.9E-147 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Pfam PF10410 DnaB-helicase binding domain of primase 372 423 1.9E-6 T 13-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Gene3D G3DSA:3.40.1360.10 244 370 5.3E-40 T 13-10-2018 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 SMART SM00766 459 586 1.1E-27 T 13-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 MADE_000001020790 347ccb930e284c72985deafbd2f769cb 592 Gene3D G3DSA:1.20.50.20 371 428 3.2E-9 T 13-10-2018 MADE_1004675 a7a40c95c2f0f55af48c375584dbbec5 303 Gene3D G3DSA:3.40.50.300 28 186 9.0E-16 T 13-10-2018 MADE_1004675 a7a40c95c2f0f55af48c375584dbbec5 303 SUPERFAMILY SSF52540 5 255 1.77E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004675 a7a40c95c2f0f55af48c375584dbbec5 303 Pfam PF13401 AAA domain 42 172 1.5E-22 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004675 a7a40c95c2f0f55af48c375584dbbec5 303 SMART SM00382 42 196 3.7E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001023590 04907c6bf96cd554cdc4ebe23172837d 363 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 31 40 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MADE_000001023590 04907c6bf96cd554cdc4ebe23172837d 363 Gene3D G3DSA:3.20.20.210 11 363 5.5E-160 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MADE_000001023590 04907c6bf96cd554cdc4ebe23172837d 363 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 14 356 5.6E-142 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MADE_000001023590 04907c6bf96cd554cdc4ebe23172837d 363 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 15 358 50.217 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MADE_000001023590 04907c6bf96cd554cdc4ebe23172837d 363 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 18 356 4.3E-138 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MADE_000001023590 04907c6bf96cd554cdc4ebe23172837d 363 SUPERFAMILY SSF51726 11 362 7.59E-123 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 MADE_000001023590 04907c6bf96cd554cdc4ebe23172837d 363 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 151 167 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 Gene3D G3DSA:3.40.720.10 47 441 6.7E-127 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 SUPERFAMILY SSF53649 35 449 2.88E-101 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 PRINTS PR00113 Alkaline phosphatase signature 250 279 2.0E-27 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 PRINTS PR00113 Alkaline phosphatase signature 43 63 2.0E-27 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 PRINTS PR00113 Alkaline phosphatase signature 185 195 2.0E-27 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 PRINTS PR00113 Alkaline phosphatase signature 98 113 2.0E-27 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 PRINTS PR00113 Alkaline phosphatase signature 135 155 2.0E-27 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 Gene3D G3DSA:1.10.60.40 326 410 6.7E-127 T 13-10-2018 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 ProSitePatterns PS00123 Alkaline phosphatase active site. 98 106 - T 13-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 SMART SM00098 44 451 9.1E-86 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1013045 1bae1524a84c15584ab66719c2372230 488 Pfam PF00245 Alkaline phosphatase 44 447 6.6E-90 T 13-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 Pfam PF03471 Transporter associated domain 208 281 4.4E-19 T 13-10-2018 IPR005170 Transporter-associated domain MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 SUPERFAMILY SSF54631 63 200 4.3E-35 T 13-10-2018 MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 Gene3D G3DSA:3.30.465.10 196 281 3.1E-25 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 SMART SM00116 139 187 0.037 T 13-10-2018 IPR000644 CBS domain MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 SMART SM00116 76 125 1.6 T 13-10-2018 IPR000644 CBS domain MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 Pfam PF00571 CBS domain 67 123 1.0E-6 T 13-10-2018 IPR000644 CBS domain MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 Pfam PF00571 CBS domain 135 187 1.7E-6 T 13-10-2018 IPR000644 CBS domain MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 SMART SM01091 205 283 7.2E-24 T 13-10-2018 IPR005170 Transporter-associated domain MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 SUPERFAMILY SSF56176 203 282 2.67E-20 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_1007140 ab5e53308c3e227d4a8b376837cbe147 285 Gene3D G3DSA:3.10.580.10 46 195 7.3E-54 T 13-10-2018 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 Gene3D G3DSA:3.50.50.60 480 633 2.6E-117 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 SUPERFAMILY SSF51395 11 371 4.64E-107 T 13-10-2018 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 Gene3D G3DSA:3.20.20.70 11 378 6.0E-117 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 386 405 1.1E-15 T 13-10-2018 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 508 526 1.1E-15 T 13-10-2018 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 468 486 1.1E-15 T 13-10-2018 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 626 642 1.1E-15 T 13-10-2018 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 SUPERFAMILY SSF51905 479 635 1.17E-20 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 385 407 3.0E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 504 528 3.0E-6 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 Gene3D G3DSA:3.40.50.720 384 673 2.6E-117 T 13-10-2018 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 15 336 1.4E-75 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 385 660 5.9E-26 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1015370 29f7ea353d2f295452aacc6f6d408b31 680 SUPERFAMILY SSF51971 342 528 1.77E-41 T 13-10-2018 MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 Gene3D G3DSA:3.40.50.300 349 526 6.3E-52 T 13-10-2018 MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 Gene3D G3DSA:3.90.1570.30 191 339 1.9E-27 T 13-10-2018 MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 Pfam PF08463 EcoEI R protein C-terminal 988 1126 4.6E-14 T 13-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 Gene3D G3DSA:3.40.50.300 534 767 4.2E-51 T 13-10-2018 MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 SUPERFAMILY SSF52540 475 727 1.83E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 SUPERFAMILY SSF52540 310 531 5.21E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 SMART SM00487 355 537 1.1E-20 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 Pfam PF04851 Type III restriction enzyme, res subunit 360 512 3.0E-34 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MADE_1016840 6e0ae916a31d43358cb26f17ce08a1fd 1141 Pfam PF13643 Domain of unknown function (DUF4145) 20 112 2.9E-10 T 13-10-2018 IPR025285 Domain of unknown function DUF4145 MADE_1000670 649ca8183b1ff99c6b03d207a4bc3ba7 260 Gene3D G3DSA:3.60.15.10 3 258 3.8E-34 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1000670 649ca8183b1ff99c6b03d207a4bc3ba7 260 Pfam PF00753 Metallo-beta-lactamase superfamily 39 216 2.5E-13 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1000670 649ca8183b1ff99c6b03d207a4bc3ba7 260 SUPERFAMILY SSF56281 15 232 2.49E-35 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1000670 649ca8183b1ff99c6b03d207a4bc3ba7 260 SMART SM00849 17 216 2.1E-18 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 SUPERFAMILY SSF51735 11 242 8.89E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 Gene3D G3DSA:3.40.50.720 3 247 2.1E-68 T 13-10-2018 MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 7.3E-20 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 7.3E-20 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 7.3E-20 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 7.3E-20 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 7.3E-20 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 7.3E-20 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 Pfam PF00106 short chain dehydrogenase 14 210 9.6E-50 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009585 93793cc09de36c2035d43975879a8ed6 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1016130 beff2cc5bbae3b523caf9d9960aa4c75 75 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 20 61 4.3E-9 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MADE_1016130 beff2cc5bbae3b523caf9d9960aa4c75 75 SUPERFAMILY SSF143120 1 71 7.98E-13 T 13-10-2018 IPR036165 YefM-like superfamily MADE_1016130 beff2cc5bbae3b523caf9d9960aa4c75 75 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 20 51 5.6E-8 T 13-10-2018 MADE_1014430 6de10563e705adfc5f9b0482e021fd7f 129 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1014430 6de10563e705adfc5f9b0482e021fd7f 129 SUPERFAMILY SSF51230 3 128 6.02E-48 T 13-10-2018 IPR011053 Single hybrid motif MADE_1014430 6de10563e705adfc5f9b0482e021fd7f 129 Pfam PF01597 Glycine cleavage H-protein 8 128 9.3E-49 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate MADE_1014430 6de10563e705adfc5f9b0482e021fd7f 129 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 128 9.9E-56 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MADE_1014430 6de10563e705adfc5f9b0482e021fd7f 129 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 42.289 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 MADE_1014430 6de10563e705adfc5f9b0482e021fd7f 129 Gene3D G3DSA:2.40.50.100 2 129 1.5E-52 T 13-10-2018 MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 Gene3D G3DSA:3.30.450.20 291 413 4.0E-15 T 13-10-2018 MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 Pfam PF00563 EAL domain 611 843 2.0E-64 T 13-10-2018 IPR001633 EAL domain MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 SMART SM00267 411 591 0.0017 T 13-10-2018 IPR000160 GGDEF domain MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 Gene3D G3DSA:3.30.450.20 157 279 7.8E-6 T 13-10-2018 MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 Pfam PF00990 Diguanylate cyclase, GGDEF domain 422 542 3.5E-7 T 13-10-2018 IPR000160 GGDEF domain MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 SUPERFAMILY SSF55073 428 549 4.94E-7 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 SMART SM00091 164 231 20.0 T 13-10-2018 IPR000014 PAS domain MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 SMART SM00091 295 361 0.0086 T 13-10-2018 IPR000014 PAS domain MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 Pfam PF13426 PAS domain 305 410 5.5E-10 T 13-10-2018 IPR000014 PAS domain MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 Gene3D G3DSA:3.30.70.270 421 577 6.4E-13 T 13-10-2018 MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 Gene3D G3DSA:3.20.20.450 604 856 1.1E-78 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 SUPERFAMILY SSF141868 611 853 4.58E-74 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 SUPERFAMILY SSF55785 300 409 9.83E-12 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 SMART SM00052 604 848 4.6E-89 T 13-10-2018 IPR001633 EAL domain MADE_1007070 4016fb3a49ceab92a6b8ac42a1f39c4d 858 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 299 411 9.0E-12 T 13-10-2018 IPR000014 PAS domain MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:2.40.270.10 791 833 7.0E-7 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:3.90.1100.10 646 714 5.8E-21 T 13-10-2018 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:3.90.1100.10 18 173 3.5E-58 T 13-10-2018 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:2.40.50.100 715 789 2.3E-32 T 13-10-2018 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:3.90.1800.10 1252 1306 8.1E-11 T 13-10-2018 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1342 12.302 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Pfam PF00562 RNA polymerase Rpb2, domain 6 718 1264 8.8E-158 T 13-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:2.40.270.10 1036 1242 7.1E-89 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Pfam PF04560 RNA polymerase Rpb2, domain 7 1266 1341 3.2E-27 T 13-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Pfam PF04565 RNA polymerase Rpb2, domain 3 514 581 4.1E-30 T 13-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Pfam PF04563 RNA polymerase beta subunit 26 501 6.3E-55 T 13-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 357 455 1.6E-16 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 152 225 4.0E-7 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:3.90.1100.10 440 627 4.3E-70 T 13-10-2018 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1064 1076 - T 13-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1339 0.0 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Pfam PF10385 RNA polymerase beta subunit external 1 domain 592 657 3.1E-21 T 13-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:3.90.1110.10 306 439 1.4E-35 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 SUPERFAMILY SSF64484 11 1340 0.0 T 13-10-2018 MADE_000001023300 68ff29a7686ae9f0f8eed39a69ebab13 1342 Gene3D G3DSA:2.40.50.150 834 954 1.1E-43 T 13-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Gene3D G3DSA:2.40.50.180 40 153 1.3E-23 T 13-10-2018 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Gene3D G3DSA:2.40.50.180 387 454 1.3E-34 T 13-10-2018 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 SMART SM00260 364 503 3.6E-24 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 SMART SM00260 19 157 2.0E-17 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 SMART SM00260 190 332 3.9E-26 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Gene3D G3DSA:2.40.50.180 213 327 1.1E-28 T 13-10-2018 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Gene3D G3DSA:2.30.30.40 370 493 1.3E-34 T 13-10-2018 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Pfam PF01584 CheW-like domain 368 505 7.5E-31 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Pfam PF01584 CheW-like domain 194 332 9.2E-27 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Pfam PF01584 CheW-like domain 23 158 3.6E-26 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Gene3D G3DSA:2.30.30.40 25 151 1.3E-23 T 13-10-2018 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 SUPERFAMILY SSF50341 365 505 1.57E-29 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 Gene3D G3DSA:2.30.30.40 196 326 1.1E-28 T 13-10-2018 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 SUPERFAMILY SSF50341 188 335 5.49E-26 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1015095 770950eda76fda4bd59360b356e00a55 515 SUPERFAMILY SSF50341 18 158 5.62E-27 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1013490 fda4d3abb6ef19079fa99c62d07d4288 211 Pfam PF01323 DSBA-like thioredoxin domain 5 205 4.4E-41 T 13-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MADE_1013490 fda4d3abb6ef19079fa99c62d07d4288 211 Gene3D G3DSA:3.40.30.10 1 208 5.3E-70 T 13-10-2018 MADE_1013490 fda4d3abb6ef19079fa99c62d07d4288 211 SUPERFAMILY SSF52833 4 209 2.99E-50 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1010280 7eab2b9a3de5fe99c19f7923e2b901a9 300 Pfam PF01545 Cation efflux family 25 207 1.3E-38 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MADE_1010280 7eab2b9a3de5fe99c19f7923e2b901a9 300 SUPERFAMILY SSF160240 215 292 4.97E-9 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MADE_1010280 7eab2b9a3de5fe99c19f7923e2b901a9 300 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 291 2.1E-63 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MADE_1010280 7eab2b9a3de5fe99c19f7923e2b901a9 300 Gene3D G3DSA:1.20.1510.10 19 210 1.7E-39 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1010280 7eab2b9a3de5fe99c19f7923e2b901a9 300 SUPERFAMILY SSF161111 17 212 1.02E-47 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1006330 ab6bcc283c2a085b859cda4e16303f1f 309 Pfam PF00892 EamA-like transporter family 13 148 8.4E-24 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1006330 ab6bcc283c2a085b859cda4e16303f1f 309 Pfam PF00892 EamA-like transporter family 160 291 4.0E-15 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1006330 ab6bcc283c2a085b859cda4e16303f1f 309 SUPERFAMILY SSF103481 191 296 1.03E-10 T 13-10-2018 MADE_1006330 ab6bcc283c2a085b859cda4e16303f1f 309 SUPERFAMILY SSF103481 47 151 2.35E-14 T 13-10-2018 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 Gene3D G3DSA:3.90.1150.10 21 388 1.1E-149 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 218 255 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 SUPERFAMILY SSF53383 12 395 5.65E-127 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 3 399 7.2E-213 T 13-10-2018 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 Gene3D G3DSA:3.40.640.10 55 300 1.1E-149 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 PIRSF PIRSF000521 163 398 4.2E-34 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 PIRSF PIRSF000521 23 152 3.0E-6 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 12 395 1.6E-146 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 398 69.218 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 MADE_1002510 d5618a1c3772c4ab68392ee57b23f11e 402 Pfam PF00202 Aminotransferase class-III 16 395 2.9E-125 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 ProSitePatterns PS01244 Aconitase family signature 2. 508 521 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 SUPERFAMILY SSF52016 650 903 1.82E-80 T 13-10-2018 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 27 903 0.0 T 13-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 Gene3D G3DSA:3.30.499.20 3 368 1.7E-162 T 13-10-2018 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 ProSitePatterns PS00450 Aconitase family signature 1. 442 458 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 Gene3D G3DSA:3.20.19.10 668 904 7.5E-104 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 198 211 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 508 521 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 212 227 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 274 287 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 288 301 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 446 457 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 141 154 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 165 173 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 PRINTS PR00415 Aconitase family signature 368 382 4.9E-44 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 Pfam PF00330 Aconitase family (aconitate hydratase) 64 577 6.5E-183 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 Pfam PF00694 Aconitase C-terminal domain 706 833 2.7E-48 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 Gene3D G3DSA:1.10.1440.20 606 665 1.8E-18 T 13-10-2018 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 Gene3D G3DSA:3.30.499.10 369 605 4.3E-99 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1002240 efc2b74e58df7ea70763d9025226eee6 905 SUPERFAMILY SSF53732 5 642 1.27E-224 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 SMART SM01134 72 233 4.7E-64 T 13-10-2018 MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 SUPERFAMILY SSF100950 73 233 3.65E-26 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 9.1E-11 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 9.1E-11 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 Pfam PF00455 DeoR C terminal sensor domain 74 232 5.1E-49 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 Gene3D G3DSA:1.10.10.10 1 55 1.9E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 SUPERFAMILY SSF46785 3 73 2.09E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 SMART SM00420 6 58 4.6E-22 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 9.6E-21 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1001190 d95cd2bd51091058fd0c1b0eb77d9d04 252 Gene3D G3DSA:3.30.750.70 69 131 2.9E-8 T 13-10-2018 MADE_000001022920 ef01476264bbbab10f73ee22d40cd1d7 223 Gene3D G3DSA:2.60.120.10 8 130 7.2E-23 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_000001022920 ef01476264bbbab10f73ee22d40cd1d7 223 Pfam PF00027 Cyclic nucleotide-binding domain 27 114 3.0E-15 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain MADE_000001022920 ef01476264bbbab10f73ee22d40cd1d7 223 Pfam PF13545 Crp-like helix-turn-helix domain 148 212 2.2E-7 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MADE_000001022920 ef01476264bbbab10f73ee22d40cd1d7 223 Gene3D G3DSA:1.10.10.10 143 213 5.1E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001022920 ef01476264bbbab10f73ee22d40cd1d7 223 SMART SM00100 7 126 2.1E-4 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain MADE_000001022920 ef01476264bbbab10f73ee22d40cd1d7 223 SUPERFAMILY SSF51206 12 138 8.12E-26 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like MADE_000001022920 ef01476264bbbab10f73ee22d40cd1d7 223 SUPERFAMILY SSF46785 147 214 2.88E-6 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1005805 32c4ed1902126ebb68b8ba8b97679178 222 Gene3D G3DSA:3.10.25.20 161 222 3.3E-17 T 13-10-2018 MADE_1005805 32c4ed1902126ebb68b8ba8b97679178 222 SUPERFAMILY SSF50486 161 219 2.28E-17 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MADE_1005805 32c4ed1902126ebb68b8ba8b97679178 222 Gene3D G3DSA:3.40.50.170 5 158 6.4E-22 T 13-10-2018 MADE_1005805 32c4ed1902126ebb68b8ba8b97679178 222 SUPERFAMILY SSF53328 31 152 2.09E-22 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 Gene3D G3DSA:2.40.50.100 75 153 3.1E-30 T 13-10-2018 MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 1.6E-16 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 1.6E-16 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 1.6E-16 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 Pfam PF00364 Biotin-requiring enzyme 79 152 3.2E-24 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 SUPERFAMILY SSF51230 76 153 3.01E-25 T 13-10-2018 IPR011053 Single hybrid motif MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 109 126 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1019660 3a6cf2c7ee5433ed9cf0c0e32df34251 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 3.6E-57 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 MADE_1018995 aeffb6ecd9ed7d66f1aa79a65079e481 320 SUPERFAMILY SSF161111 24 216 3.92E-48 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1018995 aeffb6ecd9ed7d66f1aa79a65079e481 320 Gene3D G3DSA:1.20.1510.10 25 214 6.2E-39 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1018995 aeffb6ecd9ed7d66f1aa79a65079e481 320 Pfam PF01545 Cation efflux family 29 212 1.5E-40 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MADE_1018995 aeffb6ecd9ed7d66f1aa79a65079e481 320 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 26 294 1.2E-57 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MADE_1018995 aeffb6ecd9ed7d66f1aa79a65079e481 320 SUPERFAMILY SSF160240 222 294 4.71E-6 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 MADE_1001275 2d0f8e13a8302fd437a110773407c7c9 197 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001275 2d0f8e13a8302fd437a110773407c7c9 197 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 32 2.8E-4 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001275 2d0f8e13a8302fd437a110773407c7c9 197 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 32 2.9E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 SUPERFAMILY SSF51011 623 725 1.51E-25 T 13-10-2018 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 SUPERFAMILY SSF51445 242 621 1.44E-111 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 PIRSF PIRSF000463 2 730 2.2E-274 T 13-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 111 723 9.4E-256 T 13-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 130 202 5.0E-19 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 Gene3D G3DSA:3.20.20.80 221 622 3.0E-164 T 13-10-2018 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 95 727 42.077 T 13-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 SUPERFAMILY SSF81296 12 97 2.1E-9 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 Pfam PF00128 Alpha amylase, catalytic domain 275 346 4.5E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 SUPERFAMILY SSF81296 113 223 5.6E-24 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 SMART SM00642 247 610 1.0E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 Gene3D G3DSA:2.60.40.10 2 218 1.0E-47 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 Gene3D G3DSA:2.60.40.1180 623 728 4.2E-30 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1011665 da09c4157cc20e8c26e3a88552dac9be 730 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 628 725 1.4E-15 T 13-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 MADE_1003800 7397acf8328865ae946fbb476d1a891b 117 Gene3D G3DSA:3.30.1130.10 1 116 1.4E-33 T 13-10-2018 MADE_1003800 7397acf8328865ae946fbb476d1a891b 117 SUPERFAMILY SSF55620 1 115 2.95E-30 T 13-10-2018 MADE_1003800 7397acf8328865ae946fbb476d1a891b 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 113 2.9E-25 T 13-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1003800 7397acf8328865ae946fbb476d1a891b 117 SMART SM00905 4 114 1.6E-30 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1003800 7397acf8328865ae946fbb476d1a891b 117 TIGRFAM TIGR00526 folB_dom: FolB domain 2 116 8.7E-25 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1003800 7397acf8328865ae946fbb476d1a891b 117 Pfam PF02152 Dihydroneopterin aldolase 4 112 1.4E-29 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1000895 f3c9a0c9cde845429928617472afe515 381 Gene3D G3DSA:2.40.30.170 58 280 3.5E-71 T 13-10-2018 MADE_1000895 f3c9a0c9cde845429928617472afe515 381 SUPERFAMILY SSF111369 55 293 2.75E-72 T 13-10-2018 MADE_1000895 f3c9a0c9cde845429928617472afe515 381 Gene3D G3DSA:1.10.287.470 99 172 3.5E-71 T 13-10-2018 MADE_1000895 f3c9a0c9cde845429928617472afe515 381 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 289 2.9E-16 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1000895 f3c9a0c9cde845429928617472afe515 381 Gene3D G3DSA:2.40.50.100 64 208 3.5E-71 T 13-10-2018 MADE_1000895 f3c9a0c9cde845429928617472afe515 381 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 369 4.8E-75 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1000895 f3c9a0c9cde845429928617472afe515 381 Gene3D G3DSA:2.40.420.20 281 371 3.0E-23 T 13-10-2018 MADE_1004655 168b93c6db3003af37b74f56075f7ca9 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 6 370 6.3E-127 T 13-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 MADE_1004655 168b93c6db3003af37b74f56075f7ca9 379 Gene3D G3DSA:3.80.30.20 1 294 4.5E-97 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MADE_1004655 168b93c6db3003af37b74f56075f7ca9 379 Pfam PF04055 Radical SAM superfamily 10 174 4.3E-17 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1004655 168b93c6db3003af37b74f56075f7ca9 379 SMART SM00729 5 221 3.4E-49 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1004655 168b93c6db3003af37b74f56075f7ca9 379 SUPERFAMILY SSF102114 2 378 2.09E-110 T 13-10-2018 MADE_1004655 168b93c6db3003af37b74f56075f7ca9 379 Pfam PF06969 HemN C-terminal domain 308 368 9.0E-12 T 13-10-2018 IPR010723 HemN, C-terminal MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 SUPERFAMILY SSF46689 455 505 2.42E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 SUPERFAMILY SSF52540 186 420 2.25E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 273 288 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 211 224 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 Pfam PF01590 GAF domain 19 152 1.0E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 400 409 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 SMART SM00065 15 164 1.3E-6 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 Gene3D G3DSA:1.10.10.60 455 506 6.5E-8 T 13-10-2018 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 Pfam PF00158 Sigma-54 interaction domain 187 353 2.0E-66 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 Gene3D G3DSA:3.30.450.40 5 170 4.1E-8 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 Gene3D G3DSA:3.40.50.300 176 357 6.9E-64 T 13-10-2018 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 SMART SM00382 207 359 7.8E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 Gene3D G3DSA:1.10.8.60 358 420 1.3E-17 T 13-10-2018 MADE_1019400 54b3708034eba8e66f373e2c156368a5 506 SUPERFAMILY SSF55781 20 161 7.85E-10 T 13-10-2018 MADE_1019450 c15f6ef9d70059723b306b8bbcb81fdc 159 TIGRFAM TIGR02826 RNR_activ_nrdG3: anaerobic ribonucleoside-triphosphate reductase activating protein 9 150 2.1E-50 T 13-10-2018 IPR014191 Anaerobic ribonucleoside-triphosphate reductase activator MADE_1019450 c15f6ef9d70059723b306b8bbcb81fdc 159 SUPERFAMILY SSF102114 28 114 2.94E-5 T 13-10-2018 MADE_1019450 c15f6ef9d70059723b306b8bbcb81fdc 159 Pfam PF13353 4Fe-4S single cluster domain 27 87 7.8E-7 T 13-10-2018 MADE_1019450 c15f6ef9d70059723b306b8bbcb81fdc 159 Gene3D G3DSA:3.20.20.70 14 155 1.4E-10 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1003860 493dc345fafff9a2bc1d39542e92f72f 356 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 65 341 5.4E-65 T 13-10-2018 IPR011862 Phosphate binding protein GO:0042301 MADE_1003860 493dc345fafff9a2bc1d39542e92f72f 356 Gene3D G3DSA:3.40.190.10 73 343 7.1E-93 T 13-10-2018 MADE_1003860 493dc345fafff9a2bc1d39542e92f72f 356 Gene3D G3DSA:3.40.190.10 158 300 7.1E-93 T 13-10-2018 MADE_1003860 493dc345fafff9a2bc1d39542e92f72f 356 Pfam PF12849 PBP superfamily domain 72 329 4.9E-28 T 13-10-2018 IPR024370 PBP domain MADE_1003860 493dc345fafff9a2bc1d39542e92f72f 356 SUPERFAMILY SSF53850 72 353 7.02E-62 T 13-10-2018 MADE_1000905 97ab01c32f0e5d677bb53d6f88df0cba 165 SUPERFAMILY SSF53474 3 162 2.06E-20 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1000905 97ab01c32f0e5d677bb53d6f88df0cba 165 Gene3D G3DSA:3.40.50.1820 1 163 9.9E-38 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1000905 97ab01c32f0e5d677bb53d6f88df0cba 165 Pfam PF05728 Uncharacterised protein family (UPF0227) 5 94 2.2E-7 T 13-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 3 334 3.4E-107 T 13-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 7 15 - T 13-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 Gene3D G3DSA:3.40.50.40 208 335 3.4E-43 T 13-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 Gene3D G3DSA:3.40.50.1170 1 207 2.6E-86 T 13-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 83 93 - T 13-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 SUPERFAMILY SSF53774 2 334 1.3E-108 T 13-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 Pfam PF00710 Asparaginase, N-terminal 4 189 1.3E-65 T 13-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 SMART SM00870 4 322 1.6E-132 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 PIRSF PIRSF001220 1 333 9.9E-91 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 PRINTS PR00139 Asparaginase/glutaminase family signature 259 277 6.5E-13 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 PRINTS PR00139 Asparaginase/glutaminase family signature 82 100 6.5E-13 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 6.5E-13 T 13-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 MADE_000001021780 ae1e4eec9381d1f3e9335f5264fd9651 335 PIRSF PIRSF500176 1 331 1.6E-106 T 13-10-2018 MADE_1003880 f35c4e2b8b071bc671950b24433b486d 454 Pfam PF01618 MotA/TolQ/ExbB proton channel family 320 440 4.7E-30 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MADE_1003880 f35c4e2b8b071bc671950b24433b486d 454 PIRSF PIRSF037714 1 454 5.1E-168 T 13-10-2018 IPR017270 Putative MotA/TolQ/ExbB family protein MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 SMART SM00382 188 327 2.1E-26 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Pfam PF06480 FtsH Extracellular 8 97 1.4E-11 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 611 37.57 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Gene3D G3DSA:1.10.8.60 326 400 5.5E-29 T 13-10-2018 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Gene3D G3DSA:3.40.50.300 146 324 2.7E-70 T 13-10-2018 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Gene3D G3DSA:1.20.58.760 401 604 2.3E-73 T 13-10-2018 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 SUPERFAMILY SSF140990 406 607 1.16E-74 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Gene3D G3DSA:2.40.50.920 26 103 6.7E-21 T 13-10-2018 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 8.8E-46 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 104 597 1.7E-244 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 SUPERFAMILY SSF52540 148 395 8.91E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001021885 537a2fa628bc24b38b096ae01f09216b 648 Pfam PF01434 Peptidase family M41 386 595 2.4E-82 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PRINTS PR00073 Coprogen oxidase signature 100 124 2.1E-86 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PRINTS PR00073 Coprogen oxidase signature 41 57 2.1E-86 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PRINTS PR00073 Coprogen oxidase signature 172 201 2.1E-86 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PRINTS PR00073 Coprogen oxidase signature 272 298 2.1E-86 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PRINTS PR00073 Coprogen oxidase signature 58 79 2.1E-86 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PRINTS PR00073 Coprogen oxidase signature 135 157 2.1E-86 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PRINTS PR00073 Coprogen oxidase signature 244 271 2.1E-86 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 13 287 57.873 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 Pfam PF01218 Coproporphyrinogen III oxidase 18 307 5.9E-134 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 Gene3D G3DSA:3.40.1500.10 7 310 1.3E-139 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 SUPERFAMILY SSF102886 15 306 1.1E-139 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 PIRSF PIRSF000166 1 310 1.7E-129 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000135 ed0a340289b848dda703f9e35fa8a1b5 310 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 176 200 - T 13-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Gene3D G3DSA:3.30.450.40 26 204 2.4E-18 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Gene3D G3DSA:3.30.450.40 224 404 2.9E-18 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Gene3D G3DSA:3.20.20.450 619 865 6.9E-63 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Pfam PF00990 Diguanylate cyclase, GGDEF domain 443 600 6.1E-50 T 13-10-2018 IPR000160 GGDEF domain MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Pfam PF13185 GAF domain 52 190 9.8E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Pfam PF13185 GAF domain 250 392 2.5E-15 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SUPERFAMILY SSF55781 35 210 6.32E-19 T 13-10-2018 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SMART SM00065 51 202 0.0015 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SMART SM00065 249 401 1.3E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Gene3D G3DSA:3.30.70.270 438 618 2.1E-61 T 13-10-2018 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 Pfam PF00563 EAL domain 621 853 2.6E-58 T 13-10-2018 IPR001633 EAL domain MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SMART SM00052 615 861 4.2E-49 T 13-10-2018 IPR001633 EAL domain MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SUPERFAMILY SSF55073 448 607 1.02E-48 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SUPERFAMILY SSF55781 233 412 1.92E-22 T 13-10-2018 MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 441 605 8.8E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SUPERFAMILY SSF141868 620 855 2.88E-58 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000370 083133a45bc65a87d81514ea7efc258c 866 SMART SM00267 432 605 7.3E-65 T 13-10-2018 IPR000160 GGDEF domain MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 SUPERFAMILY SSF52317 2 191 2.2E-49 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.0E-5 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.0E-5 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 Pfam PF00117 Glutamine amidotransferase class-I 3 189 7.1E-50 T 13-10-2018 IPR017926 Glutamine amidotransferase MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 1.3E-13 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.3E-33 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.3E-33 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.3E-33 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.3E-33 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.3E-33 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 PRINTS PR00097 Anthranilate synthase component II signature 168 181 1.3E-33 T 13-10-2018 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 2 190 1.1E-75 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1002520 9829ebc7566f99119705898cd1fbfcde 194 Gene3D G3DSA:3.40.50.880 1 190 3.6E-56 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1002750 0be4fae3d9967590a3ca405a9050dcd9 325 Pfam PF02666 Phosphatidylserine decarboxylase 63 280 2.5E-59 T 13-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MADE_1002750 0be4fae3d9967590a3ca405a9050dcd9 325 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 52 283 8.6E-79 T 13-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 MADE_1002750 0be4fae3d9967590a3ca405a9050dcd9 325 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 285 44.351 T 13-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 Gene3D G3DSA:3.50.50.60 304 458 9.0E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 Gene3D G3DSA:3.50.50.60 1 219 4.8E-91 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 Pfam PF01134 Glucose inhibited division protein A 8 399 6.5E-168 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 SMART SM01228 546 617 1.1E-42 T 13-10-2018 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 Gene3D G3DSA:1.10.150.570 570 622 5.7E-23 T 13-10-2018 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 3.2E-284 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 Gene3D G3DSA:1.10.10.1800 459 550 2.0E-29 T 13-10-2018 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 SUPERFAMILY SSF51905 7 261 1.79E-52 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 Pfam PF13932 GidA associated domain 401 616 5.2E-75 T 13-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 MADE_1020510 9f4b0f43a31e2e1820a67dcf560318d7 633 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 42.902 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 MADE_1003125 6f38b8884730746a7b339df881f2cc86 100 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 92 5.9E-18 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1003125 6f38b8884730746a7b339df881f2cc86 100 Gene3D G3DSA:3.30.2310.20 1 95 1.5E-24 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1003125 6f38b8884730746a7b339df881f2cc86 100 PIRSF PIRSF029218 1 98 1.3E-28 T 13-10-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 Gene3D G3DSA:3.10.20.30 1 104 2.5E-35 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 Gene3D G3DSA:1.10.1060.10 105 236 1.6E-59 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 109 4.3E-32 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 SUPERFAMILY SSF54292 1 104 2.91E-30 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 Pfam PF13534 4Fe-4S dicluster domain 146 219 7.1E-10 T 13-10-2018 MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 SUPERFAMILY SSF46548 105 233 5.93E-41 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MADE_1009490 dcd21603e2c7f5d19ec55bae7a1aafb9 236 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 228 9.5E-89 T 13-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1001585 5bb9692f6219e1dd34c6e600e8c46845 160 Pfam PF13474 SnoaL-like domain 74 150 5.3E-10 T 13-10-2018 IPR037401 SnoaL-like domain MADE_1001585 5bb9692f6219e1dd34c6e600e8c46845 160 SUPERFAMILY SSF54427 27 150 1.69E-21 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1001585 5bb9692f6219e1dd34c6e600e8c46845 160 Gene3D G3DSA:3.10.450.50 21 159 1.4E-25 T 13-10-2018 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Gene3D G3DSA:1.10.287.130 538 638 5.1E-26 T 13-10-2018 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 SMART SM00388 575 640 3.3E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 SUPERFAMILY SSF55874 629 800 1.44E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Pfam PF00072 Response regulator receiver domain 823 933 1.8E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 776 7.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 723 737 7.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 741 751 7.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 PRINTS PR00344 Bacterial sensor protein C-terminal signature 782 795 7.9E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 SMART SM00448 821 934 2.2E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Pfam PF02743 Cache domain 206 388 1.4E-13 T 13-10-2018 IPR033479 Double Cache domain 1 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 688 796 7.8E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Pfam PF00512 His Kinase A (phospho-acceptor) domain 575 640 7.3E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Gene3D G3DSA:3.30.450.20 203 355 8.2E-17 T 13-10-2018 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 SUPERFAMILY SSF47384 561 642 1.14E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Gene3D G3DSA:3.30.565.10 639 801 1.4E-49 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 SMART SM00387 687 798 6.0E-36 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 SUPERFAMILY SSF52172 819 936 1.71E-30 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1002870 1473b9ef059325974b3926f9817d3da9 941 Gene3D G3DSA:3.40.50.2300 818 936 4.4E-32 T 13-10-2018 MADE_1019930 1e484499bf3d6d72e20a3776a8d8e697 77 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 68 3.0E-16 T 13-10-2018 IPR010648 Uncharacterised protein family UPF0270 MADE_1019930 1e484499bf3d6d72e20a3776a8d8e697 77 Gene3D G3DSA:1.10.10.610 1 75 4.2E-25 T 13-10-2018 IPR036685 YehU-like superfamily MADE_1019930 1e484499bf3d6d72e20a3776a8d8e697 77 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 69 1.2E-30 T 13-10-2018 IPR010648 Uncharacterised protein family UPF0270 MADE_1019930 1e484499bf3d6d72e20a3776a8d8e697 77 SUPERFAMILY SSF118001 1 71 1.83E-25 T 13-10-2018 IPR036685 YehU-like superfamily MADE_1019930 1e484499bf3d6d72e20a3776a8d8e697 77 PIRSF PIRSF006169 1 76 4.5E-31 T 13-10-2018 IPR010648 Uncharacterised protein family UPF0270 MADE_1020435 e7c84ad37b2cd3038da9b74576b44f19 199 SUPERFAMILY SSF52833 2 78 3.32E-20 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1020435 e7c84ad37b2cd3038da9b74576b44f19 199 Pfam PF00043 Glutathione S-transferase, C-terminal domain 108 188 1.7E-9 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal MADE_1020435 e7c84ad37b2cd3038da9b74576b44f19 199 SUPERFAMILY SSF47616 72 196 5.57E-24 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1020435 e7c84ad37b2cd3038da9b74576b44f19 199 Gene3D G3DSA:3.40.30.10 1 79 1.3E-22 T 13-10-2018 MADE_1020435 e7c84ad37b2cd3038da9b74576b44f19 199 Gene3D G3DSA:1.20.1050.10 81 196 1.7E-34 T 13-10-2018 MADE_1020435 e7c84ad37b2cd3038da9b74576b44f19 199 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 3.7E-14 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1005385 6b209161ac0ab656efd1aa94c2cf6c73 190 Pfam PF01351 Ribonuclease HII 6 182 8.7E-40 T 13-10-2018 IPR024567 Ribonuclease HII/HIII domain MADE_1005385 6b209161ac0ab656efd1aa94c2cf6c73 190 Gene3D G3DSA:3.30.420.10 1 190 1.5E-74 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1005385 6b209161ac0ab656efd1aa94c2cf6c73 190 SUPERFAMILY SSF53098 4 188 1.15E-68 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1005385 6b209161ac0ab656efd1aa94c2cf6c73 190 Hamap MF_00052_B Ribonuclease HII [rnhB]. 4 183 36.45 T 13-10-2018 IPR022898 Ribonuclease HII GO:0004523 MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 PIRSF PIRSF001467 21 198 2.4E-21 T 13-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 40 197 3.9E-37 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 Gene3D G3DSA:2.40.100.10 35 200 5.9E-53 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 79 91 8.9E-9 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 152 167 8.9E-9 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 53 68 8.9E-9 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 74 91 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MADE_1003645 ae340497f6957dc83e6f8b68753dc582 202 SUPERFAMILY SSF50891 38 199 5.41E-47 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_000001022635 9a94ad7b3d5245f5fadafaf60fd72790 871 Pfam PF00593 TonB dependent receptor 356 869 1.1E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_000001022635 9a94ad7b3d5245f5fadafaf60fd72790 871 Gene3D G3DSA:2.40.170.20 233 871 3.0E-66 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_000001022635 9a94ad7b3d5245f5fadafaf60fd72790 871 Pfam PF07715 TonB-dependent Receptor Plug Domain 108 219 2.1E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_000001022635 9a94ad7b3d5245f5fadafaf60fd72790 871 SUPERFAMILY SSF56935 84 871 1.08E-97 T 13-10-2018 MADE_000001022635 9a94ad7b3d5245f5fadafaf60fd72790 871 Gene3D G3DSA:2.170.130.10 85 229 7.3E-24 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1004940 3ee077ab3ac425393fc912fe3be21d04 265 SUPERFAMILY SSF55120 22 259 4.64E-55 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1004940 3ee077ab3ac425393fc912fe3be21d04 265 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 76 90 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1004940 3ee077ab3ac425393fc912fe3be21d04 265 Pfam PF00849 RNA pseudouridylate synthase 36 194 9.1E-32 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1004940 3ee077ab3ac425393fc912fe3be21d04 265 Gene3D G3DSA:3.30.2350.10 29 263 2.3E-55 T 13-10-2018 MADE_1015000 d4e9b50c7822c9e2ee8e7ca5b5c8cfae 172 Gene3D G3DSA:2.40.70.10 49 171 8.4E-31 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_1015000 d4e9b50c7822c9e2ee8e7ca5b5c8cfae 172 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 79 90 - T 13-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 MADE_1015000 d4e9b50c7822c9e2ee8e7ca5b5c8cfae 172 SUPERFAMILY SSF50630 58 161 7.5E-19 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_1015000 d4e9b50c7822c9e2ee8e7ca5b5c8cfae 172 Pfam PF13975 gag-polyprotein putative aspartyl protease 69 157 1.1E-22 T 13-10-2018 MADE_1015000 d4e9b50c7822c9e2ee8e7ca5b5c8cfae 172 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 55 170 3.9E-30 T 13-10-2018 IPR011969 Clan AA aspartic peptidase, C-terminal MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 Gene3D G3DSA:3.90.190.20 317 479 2.2E-49 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 17 464 3.1E-176 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 322 410 1.6E-20 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 Pfam PF08245 Mur ligase middle domain 120 300 3.6E-32 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 Gene3D G3DSA:3.40.50.720 16 103 2.1E-31 T 13-10-2018 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 15 472 43.119 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 SUPERFAMILY SSF51984 16 102 5.76E-28 T 13-10-2018 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 Pfam PF01225 Mur ligase family, catalytic domain 18 114 1.3E-23 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 SUPERFAMILY SSF53623 101 318 1.44E-73 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 SUPERFAMILY SSF53244 319 466 2.75E-48 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015145 6d9d63668e6c8dc7f71360d638615713 481 Gene3D G3DSA:3.40.1190.10 104 316 4.3E-82 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 SUPERFAMILY SSF52540 9 447 4.66E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 SUPERFAMILY SSF52540 494 803 6.63E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 Gene3D G3DSA:3.40.50.300 491 827 3.3E-126 T 13-10-2018 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 ProSitePatterns PS00211 ABC transporters family signature. 721 735 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 Gene3D G3DSA:1.20.1580.10 605 762 3.3E-126 T 13-10-2018 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 Gene3D G3DSA:3.40.50.300 9 466 2.2E-167 T 13-10-2018 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 Gene3D G3DSA:1.20.1580.10 95 365 2.2E-167 T 13-10-2018 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 Gene3D G3DSA:1.10.8.280 153 277 2.2E-167 T 13-10-2018 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 ProSitePatterns PS00211 ABC transporters family signature. 365 379 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1015485 77ecd9885c1b9ef88af8396631f794b9 834 Pfam PF00005 ABC transporter 499 751 4.8E-10 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1009045 8de4e4037c4d16bc8ad28e68a1aa2918 182 SUPERFAMILY SSF88697 27 179 5.84E-60 T 13-10-2018 IPR015947 PUA-like superfamily MADE_1009045 8de4e4037c4d16bc8ad28e68a1aa2918 182 Pfam PF01878 EVE domain 30 177 3.7E-54 T 13-10-2018 IPR002740 EVE domain MADE_1009045 8de4e4037c4d16bc8ad28e68a1aa2918 182 Gene3D G3DSA:3.10.590.10 13 181 6.6E-63 T 13-10-2018 MADE_1001690 f44608111c17925863187d1f3ca37a6d 128 Gene3D G3DSA:3.30.2320.80 1 114 7.2E-25 T 13-10-2018 MADE_1001690 f44608111c17925863187d1f3ca37a6d 128 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 13-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site MADE_1001690 f44608111c17925863187d1f3ca37a6d 128 PIRSF PIRSF004761 1 115 3.3E-24 T 13-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 MADE_1001690 f44608111c17925863187d1f3ca37a6d 128 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 111 1.0E-24 T 13-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 MADE_1001690 f44608111c17925863187d1f3ca37a6d 128 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 17.333 T 13-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 MADE_1014185 c79056cf285126b418e2250e0e18ae52 156 SUPERFAMILY SSF50630 41 139 4.7E-8 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_1014185 c79056cf285126b418e2250e0e18ae52 156 Pfam PF13650 Aspartyl protease 47 134 1.8E-9 T 13-10-2018 MADE_1014185 c79056cf285126b418e2250e0e18ae52 156 Gene3D G3DSA:2.40.70.10 27 153 5.6E-18 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 SUPERFAMILY SSF46894 135 228 3.68E-22 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 SMART SM00448 6 117 1.5E-42 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 Pfam PF00072 Response regulator receiver domain 8 117 1.6E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 SUPERFAMILY SSF52172 4 133 4.13E-41 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 1.6E-17 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 SMART SM00862 153 228 5.3E-17 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 Gene3D G3DSA:1.10.10.10 133 236 1.3E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1014060 aeb1843dfa10830d2c72a2769076e221 236 Gene3D G3DSA:3.40.50.2300 1 132 1.4E-38 T 13-10-2018 MADE_1002265 14614456a75302e4f8d8acfca3b950fb 201 SUPERFAMILY SSF52166 10 200 1.09E-73 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1002265 14614456a75302e4f8d8acfca3b950fb 201 Pfam PF00573 Ribosomal protein L4/L1 family 13 198 1.3E-65 T 13-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 MADE_1002265 14614456a75302e4f8d8acfca3b950fb 201 Gene3D G3DSA:3.40.1370.10 2 201 3.5E-71 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1002265 14614456a75302e4f8d8acfca3b950fb 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 13 198 1.5E-75 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002265 14614456a75302e4f8d8acfca3b950fb 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 201 34.358 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1011485 9f68d9b32c0f1b96de6e91f118efb627 195 Gene3D G3DSA:3.90.550.10 1 191 4.9E-37 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1011485 9f68d9b32c0f1b96de6e91f118efb627 195 Pfam PF00535 Glycosyl transferase family 2 16 178 4.5E-32 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1011485 9f68d9b32c0f1b96de6e91f118efb627 195 SUPERFAMILY SSF53448 14 188 1.76E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1006995 35d1d2194bb873386e02654eef6d0782 386 Gene3D G3DSA:1.20.1090.10 184 386 5.1E-63 T 13-10-2018 MADE_1006995 35d1d2194bb873386e02654eef6d0782 386 SUPERFAMILY SSF56796 6 384 1.44E-118 T 13-10-2018 MADE_1006995 35d1d2194bb873386e02654eef6d0782 386 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 377 4.8E-116 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MADE_1006995 35d1d2194bb873386e02654eef6d0782 386 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 13-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MADE_1006995 35d1d2194bb873386e02654eef6d0782 386 Gene3D G3DSA:3.40.50.1970 1 183 3.9E-52 T 13-10-2018 MADE_1011720 a8ce88973e6bc639938fb355d1d16e70 301 SUPERFAMILY SSF53167 50 292 8.64E-45 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MADE_1011720 a8ce88973e6bc639938fb355d1d16e70 301 Pfam PF01048 Phosphorylase superfamily 50 295 6.1E-33 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MADE_1011720 a8ce88973e6bc639938fb355d1d16e70 301 Gene3D G3DSA:3.40.50.1580 47 300 1.7E-73 T 13-10-2018 MADE_1003875 cb3e74d35201ca8b5cffe6c5cc183ad6 252 PIRSF PIRSF028069 1 252 1.9E-86 T 13-10-2018 IPR016866 Uncharacterised conserved protein UCP028069 MADE_1003875 cb3e74d35201ca8b5cffe6c5cc183ad6 252 Pfam PF11932 Protein of unknown function (DUF3450) 9 248 2.1E-95 T 13-10-2018 IPR016866 Uncharacterised conserved protein UCP028069 MADE_1018155 6995e85f9b7e63858093291469d87e23 261 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 26 260 39.408 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MADE_1018155 6995e85f9b7e63858093291469d87e23 261 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 35 260 1.4E-87 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MADE_1018155 6995e85f9b7e63858093291469d87e23 261 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 168 182 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MADE_1018155 6995e85f9b7e63858093291469d87e23 261 SUPERFAMILY SSF53335 30 259 4.34E-50 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1018155 6995e85f9b7e63858093291469d87e23 261 Pfam PF01209 ubiE/COQ5 methyltransferase family 30 260 1.3E-102 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 MADE_1018155 6995e85f9b7e63858093291469d87e23 261 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 46 61 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 MADE_1018155 6995e85f9b7e63858093291469d87e23 261 Gene3D G3DSA:3.40.50.150 41 261 3.2E-76 T 13-10-2018 MADE_000001022295 fc9ce5505241f0c37c71b966bb0fc3df 423 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 16 355 4.8E-124 T 13-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MADE_000001022295 fc9ce5505241f0c37c71b966bb0fc3df 423 Pfam PF08388 Group II intron, maturase-specific domain 293 367 1.9E-17 T 13-10-2018 IPR013597 Group II intron, maturase-specific MADE_000001022295 fc9ce5505241f0c37c71b966bb0fc3df 423 Gene3D G3DSA:3.30.70.270 188 289 3.7E-5 T 13-10-2018 MADE_000001022295 fc9ce5505241f0c37c71b966bb0fc3df 423 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 280 9.4E-44 T 13-10-2018 IPR000477 Reverse transcriptase domain MADE_000001022295 fc9ce5505241f0c37c71b966bb0fc3df 423 SUPERFAMILY SSF56672 21 367 3.61E-53 T 13-10-2018 MADE_1013170 88481daf193e8d47ce67df80b2a9d733 632 PIRSF PIRSF001589 1 632 1.0E-167 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MADE_1013170 88481daf193e8d47ce67df80b2a9d733 632 Gene3D G3DSA:3.60.20.10 3 185 4.1E-70 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1013170 88481daf193e8d47ce67df80b2a9d733 632 Pfam PF13537 Glutamine amidotransferase domain 47 166 1.0E-50 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain MADE_1013170 88481daf193e8d47ce67df80b2a9d733 632 Pfam PF00733 Asparagine synthase 240 621 1.1E-94 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MADE_1013170 88481daf193e8d47ce67df80b2a9d733 632 SUPERFAMILY SSF56235 2 223 4.29E-69 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1013170 88481daf193e8d47ce67df80b2a9d733 632 SUPERFAMILY SSF52402 230 617 4.93E-76 T 13-10-2018 MADE_1013170 88481daf193e8d47ce67df80b2a9d733 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 557 7.3E-154 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MADE_1020405 71b4f57915660945ff66039b743b9542 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.3E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1020405 71b4f57915660945ff66039b743b9542 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.3E-5 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1020405 71b4f57915660945ff66039b743b9542 333 SUPERFAMILY SSF47413 2 59 1.71E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1020405 71b4f57915660945ff66039b743b9542 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.8E-19 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1020405 71b4f57915660945ff66039b743b9542 333 Gene3D G3DSA:1.10.260.40 1 54 8.1E-23 T 13-10-2018 MADE_1020405 71b4f57915660945ff66039b743b9542 333 SUPERFAMILY SSF53822 61 328 1.23E-78 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1020405 71b4f57915660945ff66039b743b9542 333 Gene3D G3DSA:3.40.50.2300 55 305 7.5E-74 T 13-10-2018 MADE_1020405 71b4f57915660945ff66039b743b9542 333 SMART SM00354 1 71 3.4E-31 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1020405 71b4f57915660945ff66039b743b9542 333 Gene3D G3DSA:3.40.50.2300 160 289 7.5E-74 T 13-10-2018 MADE_1020405 71b4f57915660945ff66039b743b9542 333 Pfam PF13377 Periplasmic binding protein-like domain 168 327 1.5E-29 T 13-10-2018 MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 4.9E-38 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 SUPERFAMILY SSF53901 214 411 2.7E-71 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 410 3.4E-197 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 Gene3D G3DSA:3.40.47.10 257 401 2.5E-53 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 PIRSF PIRSF000447 1 412 8.6E-194 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 Gene3D G3DSA:3.40.47.10 1 255 2.8E-93 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 1.3E-63 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 SUPERFAMILY SSF53901 4 252 6.21E-79 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008710 b790b9196414d88e27e09d724a6860f1 412 SMART SM00825 Beta-ketoacyl synthase 6 412 2.5E-15 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 PIRSF PIRSF039144 1 112 5.0E-57 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 SUPERFAMILY SSF54913 1 112 5.84E-46 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.4E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 SMART SM00938 4 105 7.7E-69 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 Gene3D G3DSA:3.30.70.120 1 112 3.5E-49 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 PRINTS PR00340 P-II protein signature 2 17 2.4E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 PRINTS PR00340 P-II protein signature 52 75 2.4E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 PRINTS PR00340 P-II protein signature 23 41 2.4E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 PRINTS PR00340 P-II protein signature 83 103 2.4E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MADE_1012580 4faa687800179080c786de6a6f3c2be9 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MADE_1009250 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF01548 Transposase 7 145 4.0E-12 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1009250 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 290 4.0E-14 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1003165 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF01548 Transposase 7 145 4.0E-12 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1003165 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 290 4.0E-14 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1003265 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF01548 Transposase 7 145 4.0E-12 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1003265 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 290 4.0E-14 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1011010 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF01548 Transposase 7 145 4.0E-12 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1011010 9cb31a58ab5e426381a4d49d4cc97b41 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 290 4.0E-14 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_000001022020 a379ad7859c2da45d0bd0284d6fdfd2a 772 SUPERFAMILY SSF82866 567 765 1.23E-31 T 13-10-2018 MADE_000001022020 a379ad7859c2da45d0bd0284d6fdfd2a 772 Gene3D G3DSA:1.20.1640.10 204 391 7.3E-7 T 13-10-2018 MADE_000001022020 a379ad7859c2da45d0bd0284d6fdfd2a 772 Gene3D G3DSA:1.20.1640.10 587 770 1.0E-12 T 13-10-2018 MADE_000001022020 a379ad7859c2da45d0bd0284d6fdfd2a 772 SUPERFAMILY SSF82866 174 377 1.11E-26 T 13-10-2018 MADE_000001022020 a379ad7859c2da45d0bd0284d6fdfd2a 772 Pfam PF03176 MMPL family 468 762 3.2E-16 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MADE_000001022020 a379ad7859c2da45d0bd0284d6fdfd2a 772 Pfam PF03176 MMPL family 142 411 1.3E-10 T 13-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 SUPERFAMILY SSF46894 148 213 1.77E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 Gene3D G3DSA:3.40.50.2300 26 142 2.7E-18 T 13-10-2018 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 SMART SM00421 156 213 3.9E-20 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 Gene3D G3DSA:1.10.10.10 148 216 1.9E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 212 9.8E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 1.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 1.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016385 7abe57051865b81d1a3d0ed7daefc7fa 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 1.2E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 SMART SM00341 210 290 6.2E-11 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 Pfam PF00570 HRDC domain 213 280 4.9E-15 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 Gene3D G3DSA:3.30.420.10 1 194 7.6E-65 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 SMART SM00474 3 171 4.9E-38 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 Hamap MF_01899 Ribonuclease D [rnd]. 3 380 39.439 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 SUPERFAMILY SSF47819 301 382 2.8E-15 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 SUPERFAMILY SSF47819 193 290 3.27E-25 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 Pfam PF01612 3'-5' exonuclease 3 170 3.2E-38 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 SUPERFAMILY SSF53098 1 210 1.52E-63 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 TIGRFAM TIGR01388 rnd: ribonuclease D 5 373 3.6E-113 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 Gene3D G3DSA:1.10.150.80 299 384 7.7E-25 T 13-10-2018 MADE_1012205 ff8f044bdb071f3b7d57282ed43e0d09 385 Gene3D G3DSA:1.10.150.80 195 293 5.0E-21 T 13-10-2018 MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 Gene3D G3DSA:3.50.50.60 264 404 3.4E-92 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 Pfam PF04273 Putative phosphatase (DUF442) 3 108 9.8E-34 T 13-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 Gene3D G3DSA:3.90.190.10 1 138 3.3E-37 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 151 272 3.5E-8 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 SUPERFAMILY SSF51905 262 404 1.36E-20 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 5 135 5.3E-38 T 13-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 SUPERFAMILY SSF51905 152 468 6.35E-27 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1000425 9c62ffee1849227b3f99495ee43e11f9 557 Gene3D G3DSA:3.50.50.60 152 468 3.4E-92 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1002515 aad66743cb7deee9de854020a812ef0c 406 Gene3D G3DSA:1.10.3210.10 103 391 1.3E-28 T 13-10-2018 MADE_1002515 aad66743cb7deee9de854020a812ef0c 406 Pfam PF08668 HDOD domain 123 282 1.6E-11 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD MADE_1002515 aad66743cb7deee9de854020a812ef0c 406 SUPERFAMILY SSF109604 123 310 1.76E-19 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 107 315 1.5E-78 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.50.320 413 484 4.6E-15 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.50.320 497 570 3.9E-14 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.50.320 582 656 1.2E-17 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 SUPERFAMILY SSF111369 124 320 3.14E-18 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.30.170 110 123 4.0E-12 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.420.20 98 109 4.0E-12 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.50.100 124 158 4.0E-12 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:1.10.287.470 159 174 4.0E-12 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.420.20 323 412 9.5E-23 T 13-10-2018 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Pfam PF11604 Copper binding periplasmic protein CusF 417 481 1.2E-20 T 13-10-2018 IPR021647 Copper binding periplasmic protein CusF MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Pfam PF11604 Copper binding periplasmic protein CusF 588 653 2.2E-21 T 13-10-2018 IPR021647 Copper binding periplasmic protein CusF MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Pfam PF11604 Copper binding periplasmic protein CusF 502 567 8.7E-18 T 13-10-2018 IPR021647 Copper binding periplasmic protein CusF MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 97 394 3.3E-39 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1001550 843c58358403e3e6c523fd7504e05d88 672 Gene3D G3DSA:2.40.30.170 225 322 1.0E-24 T 13-10-2018 MADE_1015965 36d67b9ca2d61986ad85159492b303b4 391 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 390 6.3E-103 T 13-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 MADE_1015965 36d67b9ca2d61986ad85159492b303b4 391 SUPERFAMILY SSF53383 5 390 8.87E-85 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1015965 36d67b9ca2d61986ad85159492b303b4 391 Pfam PF00155 Aminotransferase class I and II 54 389 3.5E-35 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1015965 36d67b9ca2d61986ad85159492b303b4 391 Gene3D G3DSA:3.90.1150.10 13 389 5.6E-119 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1015965 36d67b9ca2d61986ad85159492b303b4 391 Gene3D G3DSA:3.40.640.10 66 303 5.6E-119 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1004205 1d560c9c3b12c01ff545bb67be860947 182 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 20 171 3.2E-46 T 13-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MADE_1004205 1d560c9c3b12c01ff545bb67be860947 182 PIRSF PIRSF006118 7 181 4.5E-62 T 13-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 MADE_1004205 1d560c9c3b12c01ff545bb67be860947 182 SUPERFAMILY SSF56784 17 175 1.33E-38 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1004205 1d560c9c3b12c01ff545bb67be860947 182 Gene3D G3DSA:3.40.50.1000 1 182 1.4E-51 T 13-10-2018 IPR023214 HAD superfamily MADE_1004205 1d560c9c3b12c01ff545bb67be860947 182 Pfam PF08282 haloacid dehalogenase-like hydrolase 84 152 1.1E-11 T 13-10-2018 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Pfam PF05190 MutS family domain IV 417 505 6.3E-31 T 13-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 SUPERFAMILY SSF55271 1 106 9.02E-40 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 SMART SM00534 596 783 1.4E-114 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 858 0.0 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Pfam PF01624 MutS domain I 1 110 1.7E-40 T 13-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Pfam PF05192 MutS domain III 260 548 1.5E-41 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 SMART SM00533 274 580 3.8E-98 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 SUPERFAMILY SSF52540 556 787 7.34E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Gene3D G3DSA:1.10.1420.10 376 492 2.1E-106 T 13-10-2018 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Pfam PF05188 MutS domain II 119 244 2.5E-29 T 13-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Pfam PF00488 MutS domain V 599 786 3.9E-85 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 677 693 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Gene3D G3DSA:3.40.1170.10 1 112 1.4E-48 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 SUPERFAMILY SSF48334 258 554 1.15E-90 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 853 24.679 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 SUPERFAMILY SSF53150 105 257 1.02E-43 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Gene3D G3DSA:1.10.1420.10 257 548 2.1E-106 T 13-10-2018 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Gene3D G3DSA:3.40.50.300 558 839 1.4E-97 T 13-10-2018 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 Gene3D G3DSA:3.30.420.110 118 253 2.3E-39 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 MADE_1004725 f2d020c02a5f10a8f947b1abd350f01f 863 PIRSF PIRSF037677 1 827 5.5E-149 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 Gene3D G3DSA:2.40.50.180 40 159 3.5E-25 T 13-10-2018 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 Gene3D G3DSA:3.40.50.2300 184 314 1.3E-21 T 13-10-2018 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 Gene3D G3DSA:2.30.30.40 24 153 3.5E-25 T 13-10-2018 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 SMART SM00260 18 159 2.1E-19 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 SMART SM00448 185 306 4.5E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 Pfam PF00072 Response regulator receiver domain 187 303 2.9E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 Pfam PF01584 CheW-like domain 22 161 8.0E-32 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 SUPERFAMILY SSF50341 17 162 6.28E-30 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 PIRSF PIRSF002867 2 313 8.2E-100 T 13-10-2018 IPR024181 Chemotaxis response regulator CheV MADE_1013050 269f70de23a6eed63e05ecdb01aaa39b 319 SUPERFAMILY SSF52172 184 311 2.7E-21 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1010875 1c1e8d35879802047a963ba7056f5c67 465 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 40 370 9.2E-62 T 13-10-2018 IPR018642 Protein of unknown function DUF2066 MADE_000001021255 67eab0a1bca03100526d7f9b3312f4cc 376 Pfam PF07396 Phosphate-selective porin O and P 56 345 1.4E-15 T 13-10-2018 IPR010870 Phosphate-selective porin O/P MADE_000001021255 67eab0a1bca03100526d7f9b3312f4cc 376 Gene3D G3DSA:2.40.160.10 6 374 4.1E-31 T 13-10-2018 IPR023614 Porin domain superfamily MADE_1013735 9240b0991dff493f30138f68d827949a 377 Gene3D G3DSA:1.10.10.60 269 373 5.1E-28 T 13-10-2018 MADE_1013735 9240b0991dff493f30138f68d827949a 377 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 325 367 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MADE_1013735 9240b0991dff493f30138f68d827949a 377 Pfam PF01965 DJ-1/PfpI family 94 233 3.5E-15 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MADE_1013735 9240b0991dff493f30138f68d827949a 377 SMART SM00342 288 371 7.1E-27 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1013735 9240b0991dff493f30138f68d827949a 377 Gene3D G3DSA:3.40.50.880 47 260 1.4E-51 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1013735 9240b0991dff493f30138f68d827949a 377 Pfam PF12833 Helix-turn-helix domain 294 371 1.3E-22 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1013735 9240b0991dff493f30138f68d827949a 377 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 355 371 7.6E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MADE_1013735 9240b0991dff493f30138f68d827949a 377 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 340 355 7.6E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 MADE_1013735 9240b0991dff493f30138f68d827949a 377 SUPERFAMILY SSF46689 324 373 3.4E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1013735 9240b0991dff493f30138f68d827949a 377 SUPERFAMILY SSF52317 55 252 2.11E-36 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1013735 9240b0991dff493f30138f68d827949a 377 SUPERFAMILY SSF46689 274 322 3.29E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1004190 dc9af94ab3c054d4da0f0a0b00b7974f 241 SMART SM00382 28 231 5.1E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004190 dc9af94ab3c054d4da0f0a0b00b7974f 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1004190 dc9af94ab3c054d4da0f0a0b00b7974f 241 SUPERFAMILY SSF52540 4 237 5.99E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004190 dc9af94ab3c054d4da0f0a0b00b7974f 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 214 236 7.9E-7 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MADE_1004190 dc9af94ab3c054d4da0f0a0b00b7974f 241 Pfam PF00005 ABC transporter 20 166 2.5E-37 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004190 dc9af94ab3c054d4da0f0a0b00b7974f 241 Gene3D G3DSA:3.40.50.300 2 241 4.4E-71 T 13-10-2018 MADE_1004190 dc9af94ab3c054d4da0f0a0b00b7974f 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 3 241 4.1E-124 T 13-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Gene3D G3DSA:2.60.40.1180 1043 1120 9.8E-18 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 SUPERFAMILY SSF81296 377 482 4.0E-20 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 379 463 1.0E-12 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Gene3D G3DSA:2.60.40.1110 105 239 8.4E-30 T 13-10-2018 MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Pfam PF11852 Domain of unknown function (DUF3372) 945 1118 6.8E-57 T 13-10-2018 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Pfam PF03714 Bacterial pullanase-associated domain 121 223 6.6E-11 T 13-10-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 SUPERFAMILY SSF81296 242 366 8.26E-29 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Gene3D G3DSA:2.60.40.1130 252 365 5.7E-26 T 13-10-2018 MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 SUPERFAMILY SSF49452 101 238 2.16E-32 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 SUPERFAMILY SSF51011 1007 1128 5.25E-31 T 13-10-2018 MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Gene3D G3DSA:2.60.40.10 371 477 2.1E-26 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 SUPERFAMILY SSF51445 476 1004 1.23E-112 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1009530 e8c5336d1bebecba7f4c1190941a3b18 1472 Gene3D G3DSA:3.20.20.80 478 1039 7.8E-186 T 13-10-2018 MADE_000001023005 0d0d06aac2568318d202623fe53f48f5 163 Pfam PF00141 Peroxidase 29 136 6.4E-10 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_000001023005 0d0d06aac2568318d202623fe53f48f5 163 SUPERFAMILY SSF48113 2 161 6.93E-55 T 13-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_000001023005 0d0d06aac2568318d202623fe53f48f5 163 Gene3D G3DSA:1.10.520.10 1 161 3.1E-77 T 13-10-2018 MADE_000001023005 0d0d06aac2568318d202623fe53f48f5 163 Gene3D G3DSA:1.10.420.10 16 137 3.1E-77 T 13-10-2018 MADE_1018400 bde2cce2417aa7be0c33e8b65cf8a448 200 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 189 1.5E-30 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MADE_1018400 bde2cce2417aa7be0c33e8b65cf8a448 200 Pfam PF01914 MarC family integral membrane protein 4 192 4.6E-54 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 MADE_1020515 d0ebd8fb2c81a30130d582542006dea1 275 Gene3D G3DSA:3.40.50.300 47 239 3.5E-23 T 13-10-2018 MADE_1020515 d0ebd8fb2c81a30130d582542006dea1 275 SUPERFAMILY SSF52540 63 228 6.18E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020515 d0ebd8fb2c81a30130d582542006dea1 275 Pfam PF01695 IstB-like ATP binding protein 105 226 8.4E-11 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MADE_1009900 28d354645a95b777a15db1be5efde180 395 Pfam PF00676 Dehydrogenase E1 component 58 351 6.5E-96 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MADE_1009900 28d354645a95b777a15db1be5efde180 395 Gene3D G3DSA:3.40.50.970 4 392 4.9E-142 T 13-10-2018 MADE_1009900 28d354645a95b777a15db1be5efde180 395 SUPERFAMILY SSF52518 26 388 1.14E-110 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1018095 07c74f994247684f8a1fdfecf79b3c51 468 Gene3D G3DSA:3.40.630.10 35 372 2.6E-58 T 13-10-2018 MADE_1018095 07c74f994247684f8a1fdfecf79b3c51 468 Pfam PF04389 Peptidase family M28 127 328 1.2E-20 T 13-10-2018 IPR007484 Peptidase M28 MADE_1018095 07c74f994247684f8a1fdfecf79b3c51 468 SUPERFAMILY SSF53187 47 373 1.41E-50 T 13-10-2018 MADE_1018095 07c74f994247684f8a1fdfecf79b3c51 468 Gene3D G3DSA:2.60.40.10 373 459 8.3E-9 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1018095 07c74f994247684f8a1fdfecf79b3c51 468 SUPERFAMILY SSF49265 370 455 5.41E-11 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 MADE_1002680 aa08f8d09c58541227656e076feee837 247 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 242 8.4E-18 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1002680 aa08f8d09c58541227656e076feee837 247 Gene3D G3DSA:1.10.10.10 144 246 6.3E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1002680 aa08f8d09c58541227656e076feee837 247 Gene3D G3DSA:3.40.50.2300 6 143 4.6E-37 T 13-10-2018 MADE_1002680 aa08f8d09c58541227656e076feee837 247 Pfam PF00072 Response regulator receiver domain 20 130 3.1E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002680 aa08f8d09c58541227656e076feee837 247 SMART SM00862 167 242 4.9E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1002680 aa08f8d09c58541227656e076feee837 247 SUPERFAMILY SSF46894 147 243 2.01E-22 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1002680 aa08f8d09c58541227656e076feee837 247 SUPERFAMILY SSF52172 18 140 1.12E-41 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1002680 aa08f8d09c58541227656e076feee837 247 SMART SM00448 18 129 2.5E-45 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 2.6E-71 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 SUPERFAMILY SSF51905 3 336 2.31E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 Gene3D G3DSA:3.30.390.30 344 465 2.5E-45 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 41 51 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 3.3E-61 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PIRSF PIRSF000350 1 466 3.8E-88 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 2.0E-39 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 2.0E-39 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 2.0E-39 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 2.0E-39 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.0E-39 T 13-10-2018 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 Gene3D G3DSA:3.50.50.60 8 330 1.6E-118 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 452 9.4E-38 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 SUPERFAMILY SSF55424 341 463 4.12E-40 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 454 1.7E-151 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 MADE_1014970 8f651f8ac8451f4af49d2a67d39ceb98 473 Gene3D G3DSA:3.50.50.60 149 269 1.6E-118 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 SUPERFAMILY SSF55957 403 485 2.09E-18 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 SUPERFAMILY SSF53738 182 290 5.49E-27 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 183 287 4.2E-21 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 2.8E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 267 282 2.8E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 251 2.8E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 199 218 2.8E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Gene3D G3DSA:3.40.120.10 284 400 1.4E-32 T 13-10-2018 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 93 102 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 SUPERFAMILY SSF53738 5 206 7.06E-34 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Gene3D G3DSA:3.40.120.10 201 283 4.5E-29 T 13-10-2018 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 292 401 4.3E-23 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Gene3D G3DSA:3.40.120.10 4 145 6.8E-50 T 13-10-2018 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 SUPERFAMILY SSF53738 292 396 2.32E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 407 483 3.4E-10 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Gene3D G3DSA:3.30.310.50 403 485 7.0E-27 T 13-10-2018 MADE_1009460 7475bb95ec7de817b3785e4a7501e274 486 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 133 5.1E-32 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1003630 5810ee08a5039cc52fea0ac158b42d1b 174 Pfam PF13302 Acetyltransferase (GNAT) domain 12 150 1.3E-18 T 13-10-2018 IPR000182 GNAT domain MADE_1003630 5810ee08a5039cc52fea0ac158b42d1b 174 Gene3D G3DSA:3.40.630.30 1 171 1.2E-30 T 13-10-2018 MADE_1003630 5810ee08a5039cc52fea0ac158b42d1b 174 SUPERFAMILY SSF55729 5 166 1.21E-31 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_000001021805 54a8e660fcae87701d5600493c1a32f4 322 SUPERFAMILY SSF110997 249 317 1.96E-10 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MADE_000001021805 54a8e660fcae87701d5600493c1a32f4 322 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 39 192 24.402 T 13-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 MADE_000001021805 54a8e660fcae87701d5600493c1a32f4 322 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 102 308 1.4E-49 T 13-10-2018 IPR012997 Rare lipoprotein A MADE_000001021805 54a8e660fcae87701d5600493c1a32f4 322 SUPERFAMILY SSF50685 96 189 6.59E-10 T 13-10-2018 IPR036908 RlpA-like domain superfamily MADE_000001021805 54a8e660fcae87701d5600493c1a32f4 322 Pfam PF03330 Lytic transglycolase 101 188 9.6E-26 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain MADE_000001021805 54a8e660fcae87701d5600493c1a32f4 322 Pfam PF05036 Sporulation related domain 250 318 4.9E-8 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 MADE_000001021805 54a8e660fcae87701d5600493c1a32f4 322 Gene3D G3DSA:2.40.40.10 99 193 4.0E-37 T 13-10-2018 IPR036908 RlpA-like domain superfamily MADE_1010690 d71ba0ab8799fedd5eaf45fc8a86ad3d 824 Gene3D G3DSA:2.170.130.10 1 32 2.2E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1010690 d71ba0ab8799fedd5eaf45fc8a86ad3d 824 Pfam PF07715 TonB-dependent Receptor Plug Domain 1 24 8.8E-5 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1010690 d71ba0ab8799fedd5eaf45fc8a86ad3d 824 SUPERFAMILY SSF56935 1 823 2.15E-64 T 13-10-2018 MADE_1010690 d71ba0ab8799fedd5eaf45fc8a86ad3d 824 Pfam PF00593 TonB dependent receptor 371 822 2.3E-40 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 Gene3D G3DSA:1.10.8.630 2 111 2.4E-31 T 13-10-2018 MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 SMART SM00490 492 589 8.2E-6 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 SUPERFAMILY SSF52540 408 609 2.06E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 SUPERFAMILY SSF52540 169 377 2.4E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 Gene3D G3DSA:3.40.50.300 189 379 6.9E-74 T 13-10-2018 MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 Pfam PF00271 Helicase conserved C-terminal domain 518 588 1.9E-5 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 TIGRFAM TIGR00595 priA: primosomal protein N' 221 725 2.5E-178 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 Pfam PF00270 DEAD/DEAH box helicase 221 364 3.3E-13 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 Hamap MF_00983 Probable primosomal protein N' [priA]. 6 728 23.464 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 MADE_1018300 3d1e5e85aa58f6bc6aca650b740e92b6 729 SMART SM00487 195 391 7.8E-16 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 64 5.0E-37 T 13-10-2018 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 PIRSF PIRSF002599 1 71 5.6E-24 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 PRINTS PR00050 Cold shock protein signature 4 19 6.8E-16 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 PRINTS PR00050 Cold shock protein signature 40 58 6.8E-16 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 PRINTS PR00050 Cold shock protein signature 25 34 6.8E-16 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 SUPERFAMILY SSF50249 1 64 1.78E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 Pfam PF00313 'Cold-shock' DNA-binding domain 4 64 7.1E-29 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 Gene3D G3DSA:2.40.50.140 2 65 2.4E-28 T 13-10-2018 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 SMART SM00357 3 67 1.9E-25 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 MADE_000001021720 05752f288623a716c08e43bfce3e1660 72 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site MADE_1008725 d03a66a0638456fd37f97bc70c752000 222 SUPERFAMILY SSF52540 1 207 1.73E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008725 d03a66a0638456fd37f97bc70c752000 222 Pfam PF02223 Thymidylate kinase 8 196 1.9E-51 T 13-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 MADE_1008725 d03a66a0638456fd37f97bc70c752000 222 Hamap MF_00165 Thymidylate kinase [tmk]. 4 204 26.737 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MADE_1008725 d03a66a0638456fd37f97bc70c752000 222 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 196 1.7E-59 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MADE_1008725 d03a66a0638456fd37f97bc70c752000 222 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 13-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 MADE_1008725 d03a66a0638456fd37f97bc70c752000 222 Gene3D G3DSA:3.40.50.300 1 208 2.6E-63 T 13-10-2018 MADE_1018165 4f4c8db4617b37b16d267d1879835b1f 678 SUPERFAMILY SSF55486 8 675 1.17E-201 T 13-10-2018 MADE_1018165 4f4c8db4617b37b16d267d1879835b1f 678 Gene3D G3DSA:1.10.1370.10 140 608 1.2E-261 T 13-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 MADE_1018165 4f4c8db4617b37b16d267d1879835b1f 678 Gene3D G3DSA:1.10.1370.40 15 673 1.2E-261 T 13-10-2018 MADE_1018165 4f4c8db4617b37b16d267d1879835b1f 678 Pfam PF01432 Peptidase family M3 222 675 1.8E-153 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MADE_1020015 ef4787d9236a526ea17881743e9d3ed4 237 Gene3D G3DSA:3.40.50.2020 104 229 5.8E-8 T 13-10-2018 MADE_1020015 ef4787d9236a526ea17881743e9d3ed4 237 SUPERFAMILY SSF53271 50 220 4.97E-15 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like MADE_1013280 9fa2bcc002dd3fa2c09adea977567973 109 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 5.1E-35 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MADE_1013280 9fa2bcc002dd3fa2c09adea977567973 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 23.291 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MADE_1013280 9fa2bcc002dd3fa2c09adea977567973 109 PIRSF PIRSF004555 3 108 7.2E-39 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MADE_1013280 9fa2bcc002dd3fa2c09adea977567973 109 Gene3D G3DSA:3.30.1310.10 1 108 2.5E-45 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MADE_1013280 9fa2bcc002dd3fa2c09adea977567973 109 SUPERFAMILY SSF82607 10 102 1.29E-36 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily MADE_1013280 9fa2bcc002dd3fa2c09adea977567973 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 1.3E-35 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family MADE_1018545 cc6dad57f8755ac07aa76106d87c0e7d 252 Gene3D G3DSA:3.30.420.40 11 239 7.0E-50 T 13-10-2018 MADE_1018545 cc6dad57f8755ac07aa76106d87c0e7d 252 Hamap MF_01274 Type III pantothenate kinase [coaX]. 8 246 15.595 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MADE_1018545 cc6dad57f8755ac07aa76106d87c0e7d 252 SUPERFAMILY SSF53067 118 242 4.32E-24 T 13-10-2018 MADE_1018545 cc6dad57f8755ac07aa76106d87c0e7d 252 Pfam PF03309 Type III pantothenate kinase 10 191 2.1E-36 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MADE_1018545 cc6dad57f8755ac07aa76106d87c0e7d 252 SUPERFAMILY SSF53067 10 113 1.49E-19 T 13-10-2018 MADE_1018545 cc6dad57f8755ac07aa76106d87c0e7d 252 Gene3D G3DSA:3.30.420.490 119 231 7.0E-50 T 13-10-2018 MADE_1018545 cc6dad57f8755ac07aa76106d87c0e7d 252 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 10 241 1.7E-27 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 MADE_1008190 e357fc85b2400534219f2828593b1ecc 488 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 324 463 4.9E-14 T 13-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain MADE_1008190 e357fc85b2400534219f2828593b1ecc 488 Pfam PF13440 Polysaccharide biosynthesis protein 32 320 3.6E-55 T 13-10-2018 MADE_000001022870 84fc6496273bdb389706ed05d2101c1d 499 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 21 452 7.1E-119 T 13-10-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0016020|GO:0022857|GO:0055085 MADE_000001022870 84fc6496273bdb389706ed05d2101c1d 499 Gene3D G3DSA:1.10.4160.10 10 486 6.6E-133 T 13-10-2018 IPR038271 Purine-cytosine permease superfamily MADE_000001022870 84fc6496273bdb389706ed05d2101c1d 499 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 28 474 2.3E-119 T 13-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 Gene3D G3DSA:2.60.40.1760 39 244 1.3E-44 T 13-10-2018 MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 Gene3D G3DSA:2.60.40.1180 685 821 3.5E-28 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 SUPERFAMILY SSF51011 605 683 1.87E-15 T 13-10-2018 MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 SUPERFAMILY SSF51445 254 603 1.69E-69 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 Pfam PF01055 Glycosyl hydrolases family 31 245 686 2.3E-113 T 13-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 Pfam PF17137 Domain of unknown function (DUF5110) 704 778 7.0E-14 T 13-10-2018 IPR033403 Domain of unknown function DUF5110 MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 Pfam PF13802 Galactose mutarotase-like 160 223 2.0E-10 T 13-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 Gene3D G3DSA:2.60.40.1180 635 684 5.0E-15 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 Gene3D G3DSA:3.20.20.80 250 634 1.2E-138 T 13-10-2018 MADE_1019800 b459d44f3c6f88f26fcbb2db75ff4768 821 SUPERFAMILY SSF74650 33 250 5.96E-35 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MADE_1000890 dbf5ce3e065269beb41c3ebb7f50cd2d 227 SMART SM00271 166 222 3.0E-4 T 13-10-2018 IPR001623 DnaJ domain MADE_1000890 dbf5ce3e065269beb41c3ebb7f50cd2d 227 Pfam PF12339 DNA-J related protein 21 152 1.1E-36 T 13-10-2018 IPR021059 DnaJ-related protein, N-terminal MADE_1000890 dbf5ce3e065269beb41c3ebb7f50cd2d 227 Gene3D G3DSA:1.10.287.110 156 220 1.3E-12 T 13-10-2018 IPR036869 Chaperone J-domain superfamily MADE_1000890 dbf5ce3e065269beb41c3ebb7f50cd2d 227 SUPERFAMILY SSF46565 162 218 9.68E-12 T 13-10-2018 IPR036869 Chaperone J-domain superfamily MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 904 0.0 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 SUPERFAMILY SSF50677 187 339 1.31E-65 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Pfam PF08264 Anticodon-binding domain of tRNA 642 797 1.2E-43 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 SUPERFAMILY SSF46589 857 921 8.89E-16 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Gene3D G3DSA:3.90.740.10 202 232 1.9E-5 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 13 599 5.0E-217 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Gene3D G3DSA:1.10.730.10 547 790 9.4E-71 T 13-10-2018 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 51 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 922 16.259 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Gene3D G3DSA:3.90.740.10 233 290 6.8E-7 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Gene3D G3DSA:3.40.50.620 3 201 9.6E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Gene3D G3DSA:3.40.50.620 310 523 6.9E-76 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Gene3D G3DSA:1.10.287.380 850 922 5.9E-18 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 SUPERFAMILY SSF52374 1 609 1.42E-136 T 13-10-2018 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 PRINTS PR00986 Valyl-tRNA synthetase signature 227 244 5.0E-36 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 PRINTS PR00986 Valyl-tRNA synthetase signature 474 492 5.0E-36 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 PRINTS PR00986 Valyl-tRNA synthetase signature 33 44 5.0E-36 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 5.0E-36 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 PRINTS PR00986 Valyl-tRNA synthetase signature 443 464 5.0E-36 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 SUPERFAMILY SSF47323 610 872 2.06E-68 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1016050 33b6c8203a29ec018169fce185ac1192 924 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 857 921 5.8E-15 T 13-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 MADE_000001021310 d545db5cdd4c2274e1c4185b840f6f17 139 SMART SM00116 84 132 2.3E-7 T 13-10-2018 IPR000644 CBS domain MADE_000001021310 d545db5cdd4c2274e1c4185b840f6f17 139 SMART SM00116 10 57 2.4E-8 T 13-10-2018 IPR000644 CBS domain MADE_000001021310 d545db5cdd4c2274e1c4185b840f6f17 139 SUPERFAMILY SSF54631 1 133 3.42E-31 T 13-10-2018 MADE_000001021310 d545db5cdd4c2274e1c4185b840f6f17 139 Pfam PF00571 CBS domain 78 131 2.9E-14 T 13-10-2018 IPR000644 CBS domain MADE_000001021310 d545db5cdd4c2274e1c4185b840f6f17 139 Pfam PF00571 CBS domain 4 56 1.1E-11 T 13-10-2018 IPR000644 CBS domain MADE_000001021310 d545db5cdd4c2274e1c4185b840f6f17 139 Gene3D G3DSA:3.10.580.10 60 138 8.8E-17 T 13-10-2018 MADE_000001021310 d545db5cdd4c2274e1c4185b840f6f17 139 Gene3D G3DSA:3.10.580.10 1 59 1.5E-13 T 13-10-2018 MADE_1003100 5b5a9e339a2aec8b3eece77f1de750d4 348 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 306 3.0E-18 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1003100 5b5a9e339a2aec8b3eece77f1de750d4 348 Pfam PF01548 Transposase 12 156 1.6E-18 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1003150 5b5a9e339a2aec8b3eece77f1de750d4 348 Pfam PF02371 Transposase IS116/IS110/IS902 family 222 306 3.0E-18 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1003150 5b5a9e339a2aec8b3eece77f1de750d4 348 Pfam PF01548 Transposase 12 156 1.6E-18 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1001375 6b13edf1c71a169807c260f4dd8f0af4 239 Gene3D G3DSA:3.40.50.150 30 239 5.3E-71 T 13-10-2018 MADE_1001375 6b13edf1c71a169807c260f4dd8f0af4 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 48 238 1.3E-68 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MADE_1001375 6b13edf1c71a169807c260f4dd8f0af4 239 Pfam PF02390 Putative methyltransferase 64 233 5.2E-62 T 13-10-2018 MADE_1001375 6b13edf1c71a169807c260f4dd8f0af4 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 24 238 30.521 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 MADE_1001375 6b13edf1c71a169807c260f4dd8f0af4 239 SUPERFAMILY SSF53335 16 237 4.72E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 SUPERFAMILY SSF55874 264 416 1.57E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 170 267 3.2E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 Gene3D G3DSA:3.30.565.10 264 416 1.3E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 SMART SM00387 310 418 1.8E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 1.0E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 415 1.0E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 1.0E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 1.0E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 Gene3D G3DSA:3.30.450.20 1 128 1.8E-23 T 13-10-2018 MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 416 1.9E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1016655 3909ad220f0bdf236e1acdf785331496 436 SUPERFAMILY SSF47384 164 203 8.83E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 SUPERFAMILY SSF51735 1 122 1.65E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.611 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 Gene3D G3DSA:3.40.50.261 124 288 5.4E-77 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 SMART SM00881 4 100 3.5E-36 T 13-10-2018 IPR003781 CoA-binding GO:0048037 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 8.4E-41 T 13-10-2018 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 8.4E-41 T 13-10-2018 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 8.4E-41 T 13-10-2018 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 8.4E-41 T 13-10-2018 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 286 3.3E-147 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 13-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 Pfam PF00549 CoA-ligase 151 270 6.9E-21 T 13-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 13-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 Pfam PF02629 CoA binding domain 6 99 5.9E-32 T 13-10-2018 IPR003781 CoA-binding GO:0048037 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 SUPERFAMILY SSF52210 123 285 1.44E-57 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 Gene3D G3DSA:3.40.50.720 1 123 4.4E-52 T 13-10-2018 MADE_1009510 12a5b2031839b0fc8329ee210e9f6e77 290 PIRSF PIRSF001553 1 289 1.4E-135 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1014950 a1c73fd43a0832cf5d00b371399765bb 428 SUPERFAMILY SSF111369 54 298 5.75E-64 T 13-10-2018 MADE_1014950 a1c73fd43a0832cf5d00b371399765bb 428 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 374 2.5E-79 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1014950 a1c73fd43a0832cf5d00b371399765bb 428 Gene3D G3DSA:2.40.30.170 51 304 2.1E-93 T 13-10-2018 MADE_1014950 a1c73fd43a0832cf5d00b371399765bb 428 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 294 1.1E-20 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1014950 a1c73fd43a0832cf5d00b371399765bb 428 Gene3D G3DSA:2.40.420.20 305 373 2.1E-93 T 13-10-2018 MADE_1014950 a1c73fd43a0832cf5d00b371399765bb 428 Gene3D G3DSA:1.10.287.470 99 172 2.1E-93 T 13-10-2018 MADE_1014950 a1c73fd43a0832cf5d00b371399765bb 428 Gene3D G3DSA:2.40.50.100 64 207 2.1E-93 T 13-10-2018 MADE_1006970 9892ec98962a70d659ebc60f48235460 217 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 195 1.4E-54 T 13-10-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 MADE_1006970 9892ec98962a70d659ebc60f48235460 217 Gene3D G3DSA:3.40.50.150 1 211 6.5E-53 T 13-10-2018 MADE_1006970 9892ec98962a70d659ebc60f48235460 217 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 216 35.46 T 13-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 MADE_1006970 9892ec98962a70d659ebc60f48235460 217 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 204 7.8E-71 T 13-10-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 MADE_1006970 9892ec98962a70d659ebc60f48235460 217 PIRSF PIRSF023956 1 217 6.4E-69 T 13-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 MADE_1006970 9892ec98962a70d659ebc60f48235460 217 SUPERFAMILY SSF53335 1 194 1.66E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 Gene3D G3DSA:3.40.50.20 3 96 3.0E-28 T 13-10-2018 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 Gene3D G3DSA:3.30.1490.20 123 192 4.6E-74 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 16 313 6.2E-101 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 PIRSF PIRSF039102 12 57 8.2E-8 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 PIRSF PIRSF039102 54 322 5.4E-83 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 257 285 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 Pfam PF07478 D-ala D-ala ligase C-terminus 115 311 7.6E-61 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 Pfam PF01820 D-ala D-ala ligase N-terminus 16 98 1.2E-15 T 13-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 SUPERFAMILY SSF56059 108 312 2.65E-52 T 13-10-2018 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 15 315 33.641 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 SUPERFAMILY SSF52440 16 108 1.06E-26 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 75 86 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1015140 5bf7f007846dc9190cfbbe0932415f2f 322 Gene3D G3DSA:3.30.470.20 97 309 4.6E-74 T 13-10-2018 MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.1E-10 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.1E-10 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.1E-10 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 1.0E-47 T 13-10-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 Gene3D G3DSA:1.10.1660.10 1 126 7.3E-32 T 13-10-2018 MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 Pfam PF13411 MerR HTH family regulatory protein 1 68 2.9E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 SUPERFAMILY SSF46955 1 118 5.13E-32 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1010250 64752a0dd7f03182159eddfb4fd78ae6 138 SMART SM00422 1 70 1.2E-26 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1019435 7b7eb9c904ae42d2cac1b7e1fdee1f81 148 Pfam PF00005 ABC transporter 7 88 1.5E-12 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1019435 7b7eb9c904ae42d2cac1b7e1fdee1f81 148 Gene3D G3DSA:3.40.50.300 5 143 6.0E-33 T 13-10-2018 MADE_1019435 7b7eb9c904ae42d2cac1b7e1fdee1f81 148 SUPERFAMILY SSF52540 7 140 1.01E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003010 eb4f4a67ec3e52502908ec5da44eb94b 265 SMART SM00062 25 256 8.9E-4 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1003010 eb4f4a67ec3e52502908ec5da44eb94b 265 SUPERFAMILY SSF53850 24 243 1.45E-36 T 13-10-2018 MADE_1003010 eb4f4a67ec3e52502908ec5da44eb94b 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 244 9.3E-22 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1003010 eb4f4a67ec3e52502908ec5da44eb94b 265 Gene3D G3DSA:3.40.190.10 107 207 1.1E-25 T 13-10-2018 MADE_1003010 eb4f4a67ec3e52502908ec5da44eb94b 265 Gene3D G3DSA:3.40.190.10 31 243 1.1E-25 T 13-10-2018 MADE_1013370 b909c9c47bcae563d4da783a1a831baf 245 Pfam PF03746 LamB/YcsF family 2 244 4.2E-86 T 13-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MADE_1013370 b909c9c47bcae563d4da783a1a831baf 245 Gene3D G3DSA:3.20.20.370 1 245 1.3E-89 T 13-10-2018 MADE_1013370 b909c9c47bcae563d4da783a1a831baf 245 SUPERFAMILY SSF88713 1 245 3.34E-84 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 Pfam PF01047 MarR family 35 92 3.5E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 SMART SM00347 28 127 2.5E-19 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 Gene3D G3DSA:1.10.10.10 2 138 4.6E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 SUPERFAMILY SSF46785 3 142 6.39E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 2.6E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 2.6E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1004435 5ee4053c47af98fd9730923053a517f3 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 2.6E-5 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1000995 bf157e722ddfe237af4d2e00de476f45 246 Gene3D G3DSA:3.40.50.1000 12 237 9.3E-52 T 13-10-2018 IPR023214 HAD superfamily MADE_1000995 bf157e722ddfe237af4d2e00de476f45 246 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 209 9.2E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1000995 bf157e722ddfe237af4d2e00de476f45 246 Gene3D G3DSA:1.20.120.1600 24 118 9.3E-52 T 13-10-2018 MADE_1000995 bf157e722ddfe237af4d2e00de476f45 246 SUPERFAMILY SSF56784 9 246 1.27E-33 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1000995 bf157e722ddfe237af4d2e00de476f45 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 214 8.9E-16 T 13-10-2018 MADE_1002650 798714a23f008f68d64e91265a446f16 401 SUPERFAMILY SSF69864 175 400 1.7E-85 T 13-10-2018 MADE_1002650 798714a23f008f68d64e91265a446f16 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 119 130 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002650 798714a23f008f68d64e91265a446f16 401 Gene3D G3DSA:1.20.5.470 366 401 1.0E-7 T 13-10-2018 MADE_1002650 798714a23f008f68d64e91265a446f16 401 Gene3D G3DSA:3.90.1260.10 66 355 8.1E-147 T 13-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002650 798714a23f008f68d64e91265a446f16 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002650 798714a23f008f68d64e91265a446f16 401 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 394 2.8E-140 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002650 798714a23f008f68d64e91265a446f16 401 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 400 51.41 T 13-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002650 798714a23f008f68d64e91265a446f16 401 Pfam PF00764 Arginosuccinate synthase 8 394 3.6E-149 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002650 798714a23f008f68d64e91265a446f16 401 SUPERFAMILY SSF52402 5 167 1.9E-47 T 13-10-2018 MADE_1002650 798714a23f008f68d64e91265a446f16 401 Gene3D G3DSA:3.40.50.620 7 175 8.1E-147 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1001130 2bc43a1ea7e1ae0b9f50d8be2d19ef82 340 SUPERFAMILY SSF74650 3 337 4.58E-102 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MADE_1001130 2bc43a1ea7e1ae0b9f50d8be2d19ef82 340 Pfam PF01263 Aldose 1-epimerase 19 336 1.4E-78 T 13-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MADE_1001130 2bc43a1ea7e1ae0b9f50d8be2d19ef82 340 PIRSF PIRSF005096 1 340 2.2E-109 T 13-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 MADE_1001130 2bc43a1ea7e1ae0b9f50d8be2d19ef82 340 Gene3D G3DSA:2.70.98.10 7 339 3.2E-109 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 3.2E-30 T 13-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 PIRSF PIRSF001529 1 430 2.3E-177 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 Gene3D G3DSA:1.10.287.40 1 104 5.0E-19 T 13-10-2018 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 427 40.621 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 Gene3D G3DSA:3.30.930.10 105 430 4.8E-113 T 13-10-2018 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 226 405 2.1E-32 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 PRINTS PR00981 Seryl-tRNA synthetase signature 338 354 1.8E-33 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 PRINTS PR00981 Seryl-tRNA synthetase signature 281 294 1.8E-33 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 PRINTS PR00981 Seryl-tRNA synthetase signature 321 334 1.8E-33 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 PRINTS PR00981 Seryl-tRNA synthetase signature 269 281 1.8E-33 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 PRINTS PR00981 Seryl-tRNA synthetase signature 356 372 1.8E-33 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 SUPERFAMILY SSF55681 116 427 4.68E-99 T 13-10-2018 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 422 4.4E-169 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 MADE_1010695 f58bb373535572af9ede04f577dbeea8 430 SUPERFAMILY SSF46589 1 112 4.6E-30 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 18 526 1.3E-205 T 13-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 SUPERFAMILY SSF46977 432 531 3.66E-31 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 361 383 2.8E-8 T 13-10-2018 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 2.8E-8 T 13-10-2018 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 Pfam PF00890 FAD binding domain 20 398 2.9E-98 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 SUPERFAMILY SSF56425 244 358 1.64E-42 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 Gene3D G3DSA:1.20.58.100 431 545 2.9E-44 T 13-10-2018 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 Gene3D G3DSA:3.90.700.10 254 364 2.1E-150 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 Pfam PF02910 Fumarate reductase flavoprotein C-term 447 528 2.6E-14 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 PIRSF PIRSF000171 10 545 6.9E-35 T 13-10-2018 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 Gene3D G3DSA:3.50.50.60 20 410 2.1E-150 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1012550 e81930a28f884e52229663f1459cfd08 561 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 20 42 7.4E-5 T 13-10-2018 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 376 383 7.4E-5 T 13-10-2018 MADE_1012550 e81930a28f884e52229663f1459cfd08 561 SUPERFAMILY SSF51905 12 453 2.55E-68 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1015820 70e416f77ebe88740ecea7b521ea0284 136 SMART SM00450 35 132 1.7E-22 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1015820 70e416f77ebe88740ecea7b521ea0284 136 Pfam PF00581 Rhodanese-like domain 42 128 1.4E-18 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1015820 70e416f77ebe88740ecea7b521ea0284 136 Gene3D G3DSA:3.40.250.10 37 135 5.1E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1015820 70e416f77ebe88740ecea7b521ea0284 136 SUPERFAMILY SSF52821 38 133 3.14E-31 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Gene3D G3DSA:3.90.1440.10 229 368 2.9E-176 T 13-10-2018 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 SUPERFAMILY SSF81767 227 368 5.49E-42 T 13-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 PRINTS PR00906 SecA protein signature 117 127 9.7E-73 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 PRINTS PR00906 SecA protein signature 413 426 9.7E-73 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 PRINTS PR00906 SecA protein signature 376 393 9.7E-73 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 PRINTS PR00906 SecA protein signature 63 87 9.7E-73 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 PRINTS PR00906 SecA protein signature 101 115 9.7E-73 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 PRINTS PR00906 SecA protein signature 170 190 9.7E-73 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 PRINTS PR00906 SecA protein signature 339 361 9.7E-73 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Gene3D G3DSA:3.40.50.300 417 620 1.3E-91 T 13-10-2018 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 SUPERFAMILY SSF81886 620 890 3.01E-85 T 13-10-2018 IPR036266 SecA, Wing/Scaffold superfamily MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Pfam PF07516 SecA Wing and Scaffold domain 617 829 4.3E-71 T 13-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 SMART SM00957 6 402 0.0 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 ProSitePatterns PS01312 SecA family signature. 500 515 - T 13-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 SMART SM00958 228 358 9.9E-80 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Gene3D G3DSA:3.40.50.300 22 415 2.9E-176 T 13-10-2018 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 817 0.0 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 SUPERFAMILY SSF52540 416 618 1.26E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015110 9bd86a4a993a1060212794718f61a930 902 SUPERFAMILY SSF52540 5 415 5.53E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 20.022 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Gene3D G3DSA:1.10.3060.10 621 833 2.5E-80 T 13-10-2018 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Pfam PF07517 SecA DEAD-like domain 7 402 5.3E-134 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Pfam PF02810 SEC-C motif 882 900 1.8E-10 T 13-10-2018 IPR004027 SEC-C motif MADE_1015110 9bd86a4a993a1060212794718f61a930 902 Pfam PF01043 SecA preprotein cross-linking domain 232 358 1.3E-37 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 SUPERFAMILY SSF82714 188 268 2.35E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 SUPERFAMILY SSF82693 636 736 7.32E-6 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:1.20.1640.10 526 565 4.3E-161 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:3.30.70.1430 40 131 4.3E-161 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 SUPERFAMILY SSF82693 41 131 3.4E-20 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:3.30.70.1440 738 930 2.6E-140 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:1.20.1640.10 582 1087 2.6E-140 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.2E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 1.2E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 1.2E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 SUPERFAMILY SSF82866 294 506 3.66E-42 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Pfam PF00873 AcrB/AcrD/AcrF family 4 505 6.5E-138 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Pfam PF00873 AcrB/AcrD/AcrF family 579 1090 3.6E-112 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:3.30.70.1320 132 330 4.3E-161 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:1.20.1640.10 10 525 4.3E-161 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:3.30.70.1430 636 737 2.6E-140 T 13-10-2018 MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:3.30.2090.10 183 273 4.3E-161 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 SUPERFAMILY SSF82714 786 872 3.66E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 Gene3D G3DSA:3.30.2090.10 785 873 2.6E-140 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013390 e2aca95bb13f1b3a583923dc68ea77d3 1122 SUPERFAMILY SSF82866 872 1091 1.83E-51 T 13-10-2018 MADE_1016055 8ddd3e632dc85020a9a0ff7b87b6e06b 140 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 135 4.7E-33 T 13-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 MADE_1016055 8ddd3e632dc85020a9a0ff7b87b6e06b 140 SUPERFAMILY SSF102400 1 137 1.57E-36 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily MADE_1016055 8ddd3e632dc85020a9a0ff7b87b6e06b 140 Gene3D G3DSA:3.40.50.10110 1 139 1.5E-40 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 PIRSF PIRSF000804 1 366 3.9E-122 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 365 3.4E-41 T 13-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 SUPERFAMILY SSF55979 1 118 5.3E-30 T 13-10-2018 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 Gene3D G3DSA:3.10.150.10 125 247 1.1E-36 T 13-10-2018 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 6.3E-114 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 Gene3D G3DSA:3.10.150.10 248 366 1.4E-41 T 13-10-2018 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 Gene3D G3DSA:3.10.150.10 1 123 3.3E-42 T 13-10-2018 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 243 3.7E-35 T 13-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 SUPERFAMILY SSF55979 245 366 2.1E-38 T 13-10-2018 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 4.2E-38 T 13-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 SUPERFAMILY SSF55979 125 244 2.08E-29 T 13-10-2018 MADE_1000015 98c76d87d7f9264f6a5e18a9f3d818f9 366 SMART SM00480 17 362 4.5E-154 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 SUPERFAMILY SSF50156 207 300 2.23E-16 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 SMART SM00228 115 186 0.0018 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 SMART SM00228 190 279 4.5E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 Pfam PF02163 Peptidase family M50 10 436 6.6E-84 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 Pfam PF13180 PDZ domain 220 287 3.4E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 SUPERFAMILY SSF50156 88 184 8.54E-14 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 Gene3D G3DSA:2.30.42.10 222 309 4.3E-19 T 13-10-2018 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 Gene3D G3DSA:2.30.42.10 126 219 1.4E-27 T 13-10-2018 MADE_1005355 8456aeabe4a1034f7e1810371939997e 450 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 449 8.7E-136 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 Pfam PF07687 Peptidase dimerisation domain 185 287 3.5E-21 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 12 390 44.169 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 15 387 6.4E-116 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 SUPERFAMILY SSF55031 189 289 2.84E-23 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 Gene3D G3DSA:3.40.630.10 19 377 3.2E-107 T 13-10-2018 MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 SUPERFAMILY SSF53187 7 389 8.2E-55 T 13-10-2018 MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 Gene3D G3DSA:3.30.70.360 189 302 3.2E-107 T 13-10-2018 MADE_1012720 2b8da32c9b62792b21d97cef537ba3e5 390 Pfam PF01546 Peptidase family M20/M25/M40 72 385 1.1E-34 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 SMART SM00267 368 540 1.2E-56 T 13-10-2018 IPR000160 GGDEF domain MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 SMART SM00052 550 796 2.2E-101 T 13-10-2018 IPR001633 EAL domain MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 Pfam PF14827 Double sensory domain of two-component sensor kinase 51 273 2.2E-14 T 13-10-2018 IPR029150 Double Cache domain 3 MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 Gene3D G3DSA:3.30.70.270 373 552 3.7E-56 T 13-10-2018 MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 Pfam PF00990 Diguanylate cyclase, GGDEF domain 379 533 6.4E-47 T 13-10-2018 IPR000160 GGDEF domain MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 SUPERFAMILY SSF141868 557 808 2.48E-85 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 Pfam PF00563 EAL domain 556 791 2.2E-73 T 13-10-2018 IPR001633 EAL domain MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 Gene3D G3DSA:3.20.20.450 553 807 1.5E-91 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 SUPERFAMILY SSF55073 384 541 1.18E-45 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1000310 3dc09de71f9ac4d2bf878f29cc749e13 814 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 375 537 2.4E-43 T 13-10-2018 IPR000160 GGDEF domain MADE_1006640 565c99554575ab5b7cc2c334b910c10d 257 Pfam PF04205 FMN-binding domain 136 215 1.4E-15 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MADE_1006640 565c99554575ab5b7cc2c334b910c10d 257 PIRSF PIRSF006091 1 122 9.8E-29 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MADE_1006640 565c99554575ab5b7cc2c334b910c10d 257 PIRSF PIRSF006091 129 232 2.2E-42 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MADE_1006640 565c99554575ab5b7cc2c334b910c10d 257 SMART SM00900 130 218 4.8E-27 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MADE_1006640 565c99554575ab5b7cc2c334b910c10d 257 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 3 220 25.891 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MADE_1006640 565c99554575ab5b7cc2c334b910c10d 257 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 137 218 6.3E-34 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 Gene3D G3DSA:3.50.50.60 233 358 1.3E-77 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 Gene3D G3DSA:2.102.10.10 2 111 8.8E-25 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 Pfam PF14759 Reductase C-terminal 443 496 1.2E-5 T 13-10-2018 IPR028202 Reductase, C-terminal MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 123 418 1.9E-45 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 SUPERFAMILY SSF51905 119 309 8.17E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 SUPERFAMILY SSF50022 1 102 3.93E-24 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 Gene3D G3DSA:3.30.390.30 443 516 4.6E-8 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 Pfam PF00355 Rieske [2Fe-2S] domain 7 88 1.0E-14 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 123 145 1.2E-7 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 290 1.2E-7 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 390 397 1.2E-7 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 SUPERFAMILY SSF55424 436 499 2.75E-14 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 Gene3D G3DSA:3.50.50.60 124 426 1.3E-77 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 143 8.6E-12 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 367 8.6E-12 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 375 397 8.6E-12 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 220 238 8.6E-12 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 283 8.6E-12 T 13-10-2018 MADE_1016525 e9713634d38dae2d61de36de3d00ac0b 521 SUPERFAMILY SSF51905 265 429 5.64E-20 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Gene3D G3DSA:1.10.287.470 179 209 2.7E-16 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Pfam PF13533 Biotin-lipoyl like 45 89 1.2E-12 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Pfam PF13437 HlyD family secretion protein 209 317 1.5E-13 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Gene3D G3DSA:1.10.287.470 116 171 3.7E-5 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 SUPERFAMILY SSF111369 179 259 3.27E-8 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Gene3D G3DSA:2.40.30.170 245 318 2.7E-16 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 323 338 2.1E-5 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 54 74 2.1E-5 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Gene3D G3DSA:2.40.50.100 210 244 2.7E-16 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Gene3D G3DSA:2.40.50.100 42 75 8.7E-15 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 Gene3D G3DSA:1.10.287.470 76 115 8.7E-15 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 SUPERFAMILY SSF111369 112 172 2.62E-6 T 13-10-2018 MADE_1000630 0af10920ae1b3438f7785de6b5fac6b0 350 SUPERFAMILY SSF111369 36 108 7.06E-8 T 13-10-2018 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 SMART SM00228 499 567 9.1E-7 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 Gene3D G3DSA:2.60.40.3650 5 184 1.2E-52 T 13-10-2018 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 Pfam PF05299 M61 glycyl aminopeptidase 281 397 9.5E-44 T 13-10-2018 IPR007963 Peptidase M61, catalytic domain MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 Pfam PF13180 PDZ domain 500 575 2.0E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 SUPERFAMILY SSF55486 191 429 1.17E-12 T 13-10-2018 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 Gene3D G3DSA:2.30.42.10 499 600 2.4E-15 T 13-10-2018 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 PIRSF PIRSF016493 1 600 7.1E-177 T 13-10-2018 IPR024191 Peptidase M61 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 SUPERFAMILY SSF50156 500 580 1.71E-9 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1009695 6704cf9e44305d26158d323fd4decc99 600 Gene3D G3DSA:1.10.390.60 187 462 6.1E-97 T 13-10-2018 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 140 1.0E-63 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 72.426 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 PIRSF PIRSF001399 1 145 4.7E-61 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 SUPERFAMILY SSF52304 1 144 4.71E-63 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 16 140 2.0E-49 T 13-10-2018 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 Gene3D G3DSA:3.40.50.9100 1 145 8.6E-67 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 13-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MADE_1019655 181a75a376effe9fe5616f36024acac3 146 Pfam PF01220 Dehydroquinase class II 2 138 1.5E-62 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 9 473 63.631 T 13-10-2018 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 353 464 7.3E-30 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 Gene3D G3DSA:3.30.390.30 352 471 1.6E-32 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 2.9E-25 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 2.9E-25 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 285 2.9E-25 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 2.9E-25 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 2.9E-25 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 210 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 414 429 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 349 370 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 48 63 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 284 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 2.1E-51 T 13-10-2018 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 SUPERFAMILY SSF51905 10 330 8.1E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 Gene3D G3DSA:3.50.50.60 14 339 5.9E-95 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 SUPERFAMILY SSF55424 352 470 4.81E-30 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 333 6.6E-58 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 Gene3D G3DSA:3.50.50.60 165 283 5.9E-95 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1016705 60951abfd1d337bc6833d7e74ec3d1ff 473 PIRSF PIRSF000350 1 470 4.0E-71 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MADE_1005380 f0b839999bea055eb564ee7c62413edc 382 SUPERFAMILY SSF53756 6 354 1.18E-32 T 13-10-2018 MADE_1005380 f0b839999bea055eb564ee7c62413edc 382 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 4 381 37.977 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MADE_1005380 f0b839999bea055eb564ee7c62413edc 382 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 3 378 1.5E-116 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MADE_1005380 f0b839999bea055eb564ee7c62413edc 382 Gene3D G3DSA:3.40.50.2000 170 301 2.7E-5 T 13-10-2018 MADE_1005380 f0b839999bea055eb564ee7c62413edc 382 Pfam PF02684 Lipid-A-disaccharide synthetase 8 376 1.2E-111 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 SUPERFAMILY SSF46894 154 213 2.82E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 5.4E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 5.4E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 5.4E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 Gene3D G3DSA:3.40.50.12740 3 219 2.1E-47 T 13-10-2018 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 SUPERFAMILY SSF52172 2 129 2.42E-25 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 211 4.8E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 SMART SM00421 158 215 2.2E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 Pfam PF00072 Response regulator receiver domain 5 116 1.1E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 175 202 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1007025 0ac94cf14635c8bb142d05d0d50865e3 222 SMART SM00448 3 116 1.8E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007465 868556400a7bc6f6f2029bc332471095 299 SUPERFAMILY SSF52540 107 289 2.17E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007465 868556400a7bc6f6f2029bc332471095 299 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 105 293 5.4E-34 T 13-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MADE_1007465 868556400a7bc6f6f2029bc332471095 299 Gene3D G3DSA:3.40.50.300 9 298 1.7E-53 T 13-10-2018 MADE_1007465 868556400a7bc6f6f2029bc332471095 299 Pfam PF13614 AAA domain 109 251 2.4E-11 T 13-10-2018 IPR025669 AAA domain MADE_1007465 868556400a7bc6f6f2029bc332471095 299 TIGRFAM TIGR03018 pepcterm_TyrKin: exopolysaccharide/PEP-CTERM locus tyrosine autokinase 71 278 7.6E-77 T 13-10-2018 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 SUPERFAMILY SSF52467 189 362 2.73E-63 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 SUPERFAMILY SSF52518 3 183 1.63E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 169 1.0E-56 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 Gene3D G3DSA:3.40.50.970 1 178 7.5E-70 T 13-10-2018 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 Gene3D G3DSA:3.40.50.970 365 565 2.3E-63 T 13-10-2018 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 5.5E-45 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 431 450 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 565 4.2E-259 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 542 1.1E-47 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 SUPERFAMILY SSF52518 372 565 5.53E-67 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1002790 e1dc4bc7b91e41fa62e28cce3552cd09 572 Gene3D G3DSA:3.40.50.1220 189 360 7.9E-61 T 13-10-2018 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 Gene3D G3DSA:1.20.272.10 242 361 1.1E-40 T 13-10-2018 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 SUPERFAMILY SSF48019 244 364 1.09E-27 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 Gene3D G3DSA:1.10.8.60 8 239 2.5E-103 T 13-10-2018 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 Gene3D G3DSA:3.40.50.300 13 177 2.5E-103 T 13-10-2018 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 SUPERFAMILY SSF52540 34 222 8.76E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.7E-46 T 13-10-2018 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 SMART SM00382 37 179 2.8E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 7.3E-137 T 13-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 Gene3D G3DSA:3.30.300.150 799 912 2.3E-25 T 13-10-2018 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 367 1.2E-28 T 13-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 MADE_1013285 79054cab4f4f1bfd3c7d89bd6421c28e 930 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 805 926 3.3E-24 T 13-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 Gene3D G3DSA:1.10.40.30 363 433 7.5E-142 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 454 40.007 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 SUPERFAMILY SSF48557 3 449 4.56E-136 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 Pfam PF00206 Lyase 6 301 1.5E-82 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.2E-26 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 2.2E-26 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 2.2E-26 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 2.2E-26 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 9.5E-67 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 9.5E-67 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 9.5E-67 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 9.5E-67 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 9.5E-67 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 9.5E-67 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 Gene3D G3DSA:1.10.275.10 1 107 1.5E-33 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 Gene3D G3DSA:1.20.200.10 108 445 7.5E-142 T 13-10-2018 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 452 6.4E-190 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 1.9E-22 T 13-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 MADE_1002645 f4cb6a5bf4fe18863423baa42020d813 460 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 TIGRFAM TIGR03030 CelA: cellulose synthase catalytic subunit (UDP-forming) 12 681 3.9E-237 T 13-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 PRINTS PR01439 Cellulose synthase subunit A signature 450 469 8.9E-21 T 13-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 PRINTS PR01439 Cellulose synthase subunit A signature 410 429 8.9E-21 T 13-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 PRINTS PR01439 Cellulose synthase subunit A signature 522 543 8.9E-21 T 13-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 PRINTS PR01439 Cellulose synthase subunit A signature 381 407 8.9E-21 T 13-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 PRINTS PR01439 Cellulose synthase subunit A signature 119 138 8.9E-21 T 13-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 PRINTS PR01439 Cellulose synthase subunit A signature 35 55 8.9E-21 T 13-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 Pfam PF00535 Glycosyl transferase family 2 113 301 1.1E-33 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 SUPERFAMILY SSF53448 109 413 6.94E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 Pfam PF07238 PilZ domain 549 645 1.1E-5 T 13-10-2018 IPR009875 PilZ domain GO:0035438 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 Pfam PF03552 Cellulose synthase 303 424 2.7E-9 T 13-10-2018 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 MADE_000001022775 6c13795486231badf2f8152b163f73f3 707 Gene3D G3DSA:3.90.550.10 102 341 2.9E-85 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1005720 f4dfea9162f37776ceece80c9cc8d4ac 461 SUPERFAMILY SSF117143 79 421 5.1E-69 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like MADE_1005720 f4dfea9162f37776ceece80c9cc8d4ac 461 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site MADE_1005720 f4dfea9162f37776ceece80c9cc8d4ac 461 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 443 3.5E-93 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G MADE_1005720 f4dfea9162f37776ceece80c9cc8d4ac 461 Pfam PF07559 Flagellar basal body protein FlaE 182 341 1.6E-27 T 13-10-2018 IPR011491 Flagellar hook protein FlgE MADE_1005720 f4dfea9162f37776ceece80c9cc8d4ac 461 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 386 460 1.8E-12 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MADE_1005720 f4dfea9162f37776ceece80c9cc8d4ac 461 Gene3D G3DSA:2.60.98.20 157 342 8.4E-18 T 13-10-2018 IPR037058 Flagellar hook protein FlgE superfamily MADE_1005720 f4dfea9162f37776ceece80c9cc8d4ac 461 Pfam PF00460 Flagella basal body rod protein 3 33 2.6E-11 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 Gene3D G3DSA:1.10.287.130 173 284 3.5E-24 T 13-10-2018 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 SMART SM00304 176 228 4.7E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 Pfam PF00672 HAMP domain 176 219 5.9E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 Gene3D G3DSA:3.30.565.10 291 439 2.6E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019790 28234d46da2d27017f453cd835b0be09 444 SMART SM00388 229 289 5.5E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 SUPERFAMILY SSF55874 279 436 1.44E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019790 28234d46da2d27017f453cd835b0be09 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 393 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 435 1.2E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 SMART SM00387 328 438 4.0E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1019790 28234d46da2d27017f453cd835b0be09 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 288 3.6E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 SUPERFAMILY SSF47384 213 289 5.3E-15 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1019790 28234d46da2d27017f453cd835b0be09 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 435 1.1E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011085 59046b1132ecde057c0fd5e1836fd279 263 Gene3D G3DSA:3.10.310.10 7 255 2.4E-83 T 13-10-2018 MADE_1011085 59046b1132ecde057c0fd5e1836fd279 263 Pfam PF02567 Phenazine biosynthesis-like protein 8 259 9.6E-54 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MADE_1011085 59046b1132ecde057c0fd5e1836fd279 263 SUPERFAMILY SSF54506 1 262 3.67E-75 T 13-10-2018 MADE_1011085 59046b1132ecde057c0fd5e1836fd279 263 Gene3D G3DSA:3.10.310.10 119 251 2.4E-83 T 13-10-2018 MADE_1011085 59046b1132ecde057c0fd5e1836fd279 263 PIRSF PIRSF016184 1 263 7.3E-49 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MADE_1011085 59046b1132ecde057c0fd5e1836fd279 263 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 263 4.3E-35 T 13-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 MADE_1006415 a14b4dfeedf043af40bab6c98d83c32d 347 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 312 3.6E-49 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MADE_1006415 a14b4dfeedf043af40bab6c98d83c32d 347 SUPERFAMILY SSF53686 19 332 1.83E-70 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MADE_1006415 a14b4dfeedf043af40bab6c98d83c32d 347 Gene3D G3DSA:3.40.50.1100 21 320 1.5E-72 T 13-10-2018 MADE_1006415 a14b4dfeedf043af40bab6c98d83c32d 347 Gene3D G3DSA:3.40.50.1100 48 154 1.5E-72 T 13-10-2018 MADE_1008060 d63edfeb4ed1b5196473339e20cd1a04 384 Gene3D G3DSA:2.30.30.60 150 199 3.1E-10 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1008060 d63edfeb4ed1b5196473339e20cd1a04 384 SUPERFAMILY SSF82689 202 301 3.66E-20 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1008060 d63edfeb4ed1b5196473339e20cd1a04 384 SUPERFAMILY SSF50182 134 200 1.28E-15 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1008060 d63edfeb4ed1b5196473339e20cd1a04 384 Gene3D G3DSA:3.30.70.100 201 294 9.7E-19 T 13-10-2018 MADE_1008060 d63edfeb4ed1b5196473339e20cd1a04 384 Pfam PF00924 Mechanosensitive ion channel 92 290 2.0E-40 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 SUPERFAMILY SSF82171 147 579 9.22E-48 T 13-10-2018 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 SUPERFAMILY SSF51338 676 1066 2.47E-17 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Pfam PF01979 Amidohydrolase family 957 1064 6.6E-14 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Gene3D G3DSA:3.20.20.140 937 1039 9.8E-19 T 13-10-2018 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Gene3D G3DSA:3.20.20.140 735 808 4.9E-21 T 13-10-2018 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Gene3D G3DSA:2.120.10.60 56 173 1.8E-21 T 13-10-2018 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 SUPERFAMILY SSF51556 734 1029 6.67E-39 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Pfam PF07676 WD40-like Beta Propeller Repeat 411 434 0.002 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Pfam PF07676 WD40-like Beta Propeller Repeat 202 218 0.0088 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Pfam PF07676 WD40-like Beta Propeller Repeat 263 279 0.012 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Pfam PF07676 WD40-like Beta Propeller Repeat 95 129 1.1E-5 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Pfam PF07676 WD40-like Beta Propeller Repeat 456 483 0.0017 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Gene3D G3DSA:2.30.40.10 690 734 4.9E-21 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Gene3D G3DSA:2.30.40.10 1040 1060 9.8E-19 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Gene3D G3DSA:2.120.10.30 175 371 4.8E-15 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1018200 d487210abe252fad454e079a71cbc979 1111 Gene3D G3DSA:2.120.10.30 372 597 6.4E-25 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1018200 d487210abe252fad454e079a71cbc979 1111 SUPERFAMILY SSF82171 60 163 1.84E-19 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:1.20.1640.10 21 504 8.3E-253 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Pfam PF00873 AcrB/AcrD/AcrF family 15 1000 1.6E-182 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 SUPERFAMILY SSF82714 192 269 8.76E-13 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:1.20.1640.10 505 997 8.3E-253 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 SUPERFAMILY SSF82714 692 776 1.24E-10 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 SUPERFAMILY SSF82866 776 1006 1.57E-50 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:3.30.70.1320 145 332 8.3E-253 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 SUPERFAMILY SSF82693 51 145 2.09E-20 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 SUPERFAMILY SSF82866 295 493 3.66E-35 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:3.30.2090.10 690 779 8.3E-253 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:3.30.70.1430 555 640 8.3E-253 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:3.30.2090.10 188 274 8.3E-253 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:3.30.70.1430 51 787 8.3E-253 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 4.8E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 PRINTS PR00702 Acriflavin resistance protein family signature 466 489 4.8E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 PRINTS PR00702 Acriflavin resistance protein family signature 21 45 4.8E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 PRINTS PR00702 Acriflavin resistance protein family signature 49 67 4.8E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 PRINTS PR00702 Acriflavin resistance protein family signature 535 552 4.8E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 4.8E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 4.8E-32 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 Gene3D G3DSA:3.30.70.1440 641 837 8.3E-253 T 13-10-2018 MADE_1013395 454ed015d2d966e086edf7f42046271f 1026 SUPERFAMILY SSF82693 145 314 4.03E-12 T 13-10-2018 MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 136 262 2.8E-15 T 13-10-2018 IPR000014 PAS domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 SUPERFAMILY SSF55785 9 128 1.29E-7 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 SMART SM00091 134 207 8.2 T 13-10-2018 IPR000014 PAS domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 SMART SM00091 6 78 0.0018 T 13-10-2018 IPR000014 PAS domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 Gene3D G3DSA:3.30.450.20 5 133 2.1E-8 T 13-10-2018 MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 Pfam PF13426 PAS domain 18 129 2.1E-5 T 13-10-2018 IPR000014 PAS domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 Pfam PF13426 PAS domain 162 254 1.1E-17 T 13-10-2018 IPR000014 PAS domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 Pfam PF00990 Diguanylate cyclase, GGDEF domain 298 456 9.7E-43 T 13-10-2018 IPR000160 GGDEF domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 SMART SM00267 287 461 7.7E-50 T 13-10-2018 IPR000160 GGDEF domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 SMART SM00086 213 255 4.0E-6 T 13-10-2018 IPR001610 PAC motif MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 SUPERFAMILY SSF55785 160 252 2.79E-22 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 Gene3D G3DSA:3.30.70.270 287 461 2.1E-51 T 13-10-2018 MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 SUPERFAMILY SSF55073 303 459 9.42E-41 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 294 460 8.0E-44 T 13-10-2018 IPR000160 GGDEF domain MADE_1016025 ac872eb00a0f6049e992954e926cc022 477 Gene3D G3DSA:3.30.450.20 134 286 1.4E-34 T 13-10-2018 MADE_000001022955 5cafe8a6e072905a86567fa8441a2a2b 341 PIRSF PIRSF006268 3 337 5.9E-95 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 MADE_000001022955 5cafe8a6e072905a86567fa8441a2a2b 341 SUPERFAMILY SSF143631 30 337 1.2E-100 T 13-10-2018 IPR003374 ApbE-like superfamily MADE_000001022955 5cafe8a6e072905a86567fa8441a2a2b 341 Gene3D G3DSA:3.10.520.20 20 341 8.5E-113 T 13-10-2018 MADE_000001022955 5cafe8a6e072905a86567fa8441a2a2b 341 Pfam PF02424 ApbE family 38 315 6.6E-87 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 SUPERFAMILY SSF69075 315 416 9.02E-22 T 13-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 SUPERFAMILY SSF69742 1 156 3.66E-47 T 13-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 401 4.4E-17 T 13-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 416 29.631 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 Gene3D G3DSA:3.30.460.30 1 156 8.8E-56 T 13-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 SUPERFAMILY SSF51735 160 313 1.67E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 PIRSF PIRSF000445 1 424 2.9E-149 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 Gene3D G3DSA:3.40.50.720 159 311 3.0E-43 T 13-10-2018 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 13-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 154 1.2E-48 T 13-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 169 304 5.2E-45 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase MADE_1007640 fcaefd3caeba15f583b017bb147b67b3 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 402 1.6E-134 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:3.30.70.1430 569 669 4.4E-274 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:1.20.1640.10 512 1022 4.4E-274 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:3.30.2090.10 717 804 4.4E-274 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:3.30.70.1440 670 865 4.4E-274 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 SUPERFAMILY SSF82866 294 493 4.84E-35 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:3.30.2090.10 181 272 4.4E-274 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013755 b74617b16613631d54a93423362aeb78 1044 SUPERFAMILY SSF82693 47 139 2.04E-17 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 SUPERFAMILY SSF82866 802 1027 3.4E-44 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Pfam PF00873 AcrB/AcrD/AcrF family 12 1025 2.0E-171 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 SUPERFAMILY SSF82693 143 327 1.23E-14 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:3.30.70.1430 47 812 4.4E-274 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 7.1E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 7.1E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 PRINTS PR00702 Acriflavin resistance protein family signature 45 63 7.1E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 7.1E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 7.1E-21 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:3.30.70.1320 140 329 4.4E-274 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 Gene3D G3DSA:1.20.1640.10 17 511 4.4E-274 T 13-10-2018 MADE_1013755 b74617b16613631d54a93423362aeb78 1044 SUPERFAMILY SSF82714 727 803 1.1E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1013755 b74617b16613631d54a93423362aeb78 1044 SUPERFAMILY SSF82714 185 268 6.15E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 Gene3D G3DSA:1.10.486.10 383 539 2.3E-128 T 13-10-2018 MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 TIGRFAM TIGR01075 uvrD: DNA helicase II 6 721 0.0 T 13-10-2018 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 Gene3D G3DSA:3.40.50.300 282 637 2.3E-128 T 13-10-2018 MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 Pfam PF13361 UvrD-like helicase C-terminal domain 278 617 2.4E-76 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 Gene3D G3DSA:3.40.50.300 10 273 1.6E-101 T 13-10-2018 MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 Gene3D G3DSA:1.10.10.160 114 187 1.6E-101 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 272 3.3E-78 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MADE_1000985 768f8ba95f89eac018428e74216d1ff9 723 SUPERFAMILY SSF52540 6 643 2.57E-180 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 Pfam PF11808 Domain of unknown function (DUF3329) 6 91 1.7E-27 T 13-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 Gene3D G3DSA:3.30.565.10 274 430 1.4E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 SUPERFAMILY SSF55785 90 197 2.51E-7 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 270 3.1E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 SMART SM00387 316 428 8.2E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 95 423 1.7E-137 T 13-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 Gene3D G3DSA:1.10.287.130 199 271 8.6E-24 T 13-10-2018 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 SUPERFAMILY SSF47384 192 270 4.51E-21 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 SUPERFAMILY SSF55874 260 424 4.85E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 427 2.9E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.3E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003855 ff8695d6b40a629f63b1eeadb9b945d7 433 SMART SM00388 205 271 7.4E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002320 1d6c13591a712261cefb76d23a4b144d 423 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 16 355 2.1E-124 T 13-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MADE_1002320 1d6c13591a712261cefb76d23a4b144d 423 Pfam PF08388 Group II intron, maturase-specific domain 293 367 2.2E-17 T 13-10-2018 IPR013597 Group II intron, maturase-specific MADE_1002320 1d6c13591a712261cefb76d23a4b144d 423 SUPERFAMILY SSF56672 21 367 1.29E-53 T 13-10-2018 MADE_1002320 1d6c13591a712261cefb76d23a4b144d 423 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 280 8.7E-44 T 13-10-2018 IPR000477 Reverse transcriptase domain MADE_1006140 2477a9a6122dddb1b6c625786ddb84dd 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 66 2.2E-13 T 13-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain MADE_1006140 2477a9a6122dddb1b6c625786ddb84dd 297 SUPERFAMILY SSF161098 90 278 6.28E-24 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1006140 2477a9a6122dddb1b6c625786ddb84dd 297 Gene3D G3DSA:1.10.3720.10 86 294 4.8E-19 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1006140 2477a9a6122dddb1b6c625786ddb84dd 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 296 4.1E-21 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 Gene3D G3DSA:3.40.1550.10 43 230 1.1E-54 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 3 319 2.7E-115 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 PRINTS PR00955 Flagellar motor switch protein FliM signature 113 132 8.4E-21 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 PRINTS PR00955 Flagellar motor switch protein FliM signature 2 15 8.4E-21 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 PRINTS PR00955 Flagellar motor switch protein FliM signature 88 104 8.4E-21 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 8.4E-21 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 250 319 7.1E-16 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 SUPERFAMILY SSF101801 247 322 7.19E-14 T 13-10-2018 IPR036429 SpoA-like superfamily MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 PIRSF PIRSF002888 1 328 4.2E-93 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 Pfam PF02154 Flagellar motor switch protein FliM 37 229 1.4E-80 T 13-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 MADE_1005935 c95e86545894ff2bc4ed685219d261f6 352 SUPERFAMILY SSF103039 4 230 6.02E-19 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1012680 dad645dfd73481262b647276a52b0eee 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 86 7.0E-27 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1012680 dad645dfd73481262b647276a52b0eee 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 1.3E-31 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1012680 dad645dfd73481262b647276a52b0eee 87 Pfam PF01649 Ribosomal protein S20 2 84 6.4E-29 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1012680 dad645dfd73481262b647276a52b0eee 87 SUPERFAMILY SSF46992 3 86 4.97E-33 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1012680 dad645dfd73481262b647276a52b0eee 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 18.371 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1012680 dad645dfd73481262b647276a52b0eee 87 Gene3D G3DSA:1.20.58.110 1 87 3.6E-32 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 Pfam PF01514 Secretory protein of YscJ/FliF family 47 234 7.3E-51 T 13-10-2018 IPR006182 Secretory protein YscJ/FliF MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 PIRSF PIRSF004862 14 564 1.5E-128 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 Gene3D G3DSA:3.30.300.30 136 235 8.3E-7 T 13-10-2018 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 Pfam PF08345 Flagellar M-ring protein C-terminal 267 434 1.4E-43 T 13-10-2018 IPR013556 Flagellar M-ring C-terminal MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 35 563 4.2E-73 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 PRINTS PR01009 Flagellar M-ring protein signature 135 153 1.3E-22 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 PRINTS PR01009 Flagellar M-ring protein signature 167 181 1.3E-22 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 PRINTS PR01009 Flagellar M-ring protein signature 358 382 1.3E-22 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 PRINTS PR01009 Flagellar M-ring protein signature 210 228 1.3E-22 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MADE_1005900 6078c4f9d7678fd0865dbd5f42680250 564 PRINTS PR01009 Flagellar M-ring protein signature 280 298 1.3E-22 T 13-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 MADE_1013380 5e333daf538decfec425243587154033 130 SUPERFAMILY SSF82784 1 129 7.07E-37 T 13-10-2018 IPR036102 OsmC/Ohr superfamily MADE_1013380 5e333daf538decfec425243587154033 130 Gene3D G3DSA:3.30.300.20 34 130 6.6E-29 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1013380 5e333daf538decfec425243587154033 130 Gene3D G3DSA:2.20.25.10 1 33 8.7E-8 T 13-10-2018 MADE_1013380 5e333daf538decfec425243587154033 130 Pfam PF02566 OsmC-like protein 27 125 8.4E-20 T 13-10-2018 IPR003718 OsmC/Ohr family MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 6 185 4.8E-18 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 182 195 1.8E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.8E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.8E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.8E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 1.8E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 Gene3D G3DSA:1.10.150.240 17 91 9.1E-68 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 31 193 7.2E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 4 198 7.1E-53 T 13-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 192 1.1E-18 T 13-10-2018 MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 SUPERFAMILY SSF56784 3 217 2.71E-42 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1002045 3dbbf5e21a7d85cc2c75eae39780a1f2 223 Gene3D G3DSA:3.40.50.1000 6 217 9.1E-68 T 13-10-2018 IPR023214 HAD superfamily MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 Pfam PF00374 Nickel-dependent hydrogenase 132 610 1.2E-197 T 13-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 Pfam PF00374 Nickel-dependent hydrogenase 44 95 2.2E-20 T 13-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 Gene3D G3DSA:1.10.645.10 128 610 8.5E-212 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 44 69 - T 13-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 SUPERFAMILY SSF56762 8 95 1.96E-32 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 601 610 - T 13-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 SUPERFAMILY SSF56762 134 610 6.15E-130 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1001675 b81fd038b94ae13c46b320a0de8454ea 625 Gene3D G3DSA:1.10.645.10 1 99 1.3E-35 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 SUPERFAMILY SSF55021 298 359 1.76E-12 T 13-10-2018 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 PIRSF PIRSF000726 3 449 5.7E-128 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 ProSitePatterns PS00324 Aspartokinase signature. 7 15 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 Gene3D G3DSA:3.30.70.260 311 383 4.7E-43 T 13-10-2018 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 Gene3D G3DSA:1.20.120.1320 43 136 1.1E-98 T 13-10-2018 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 SUPERFAMILY SSF53633 7 294 2.36E-75 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 Pfam PF00696 Amino acid kinase family 7 279 3.9E-50 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 6 449 1.7E-126 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 Gene3D G3DSA:3.40.1160.10 7 291 1.1E-98 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 Gene3D G3DSA:3.30.70.260 305 446 4.7E-43 T 13-10-2018 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 SUPERFAMILY SSF55021 376 448 6.41E-13 T 13-10-2018 MADE_1003960 1fdf8389428aa1d2e566019589ec8cf7 449 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 5 449 1.3E-122 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 Gene3D G3DSA:3.30.70.270 220 392 6.3E-21 T 13-10-2018 MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 387 2.7E-13 T 13-10-2018 IPR000160 GGDEF domain MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 Pfam PF00563 EAL domain 417 638 1.9E-48 T 13-10-2018 IPR001633 EAL domain MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 SUPERFAMILY SSF141868 409 640 7.59E-49 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 SMART SM00267 225 394 2.7E-5 T 13-10-2018 IPR000160 GGDEF domain MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 Gene3D G3DSA:3.20.20.450 400 639 1.0E-49 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 SMART SM00052 402 643 5.3E-22 T 13-10-2018 IPR001633 EAL domain MADE_1007860 965410e521f99f30e6b50c4483512d9a 644 SUPERFAMILY SSF55073 241 386 2.2E-11 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 SUPERFAMILY SSF51735 19 130 4.44E-24 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 SUPERFAMILY SSF53790 235 477 6.28E-84 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Gene3D G3DSA:3.40.50.720 19 130 1.3E-33 T 13-10-2018 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Gene3D G3DSA:3.40.1010.10 234 351 4.9E-48 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Pfam PF10414 Sirohaem synthase dimerisation region 168 225 5.1E-18 T 13-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 238 447 2.2E-52 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Gene3D G3DSA:1.10.8.210 167 228 8.4E-7 T 13-10-2018 IPR037115 Sirohaem synthase, dimerisation domain superfamily GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Hamap MF_01646 Siroheme synthase [cysG]. 19 479 49.635 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Gene3D G3DSA:3.30.950.10 352 479 9.4E-49 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 316 349 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 SUPERFAMILY SSF75615 132 225 2.88E-22 T 13-10-2018 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Gene3D G3DSA:3.30.160.110 131 166 1.1E-16 T 13-10-2018 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 22 222 1.1E-64 T 13-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 PIRSF PIRSF036426 19 479 3.9E-192 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 236 471 2.7E-96 T 13-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003520 8a6b879f2d93a2fd028a6e60a596e545 479 Pfam PF13241 Putative NAD(P)-binding 24 133 3.7E-27 T 13-10-2018 MADE_1001000 5f0c5a3397e0da549f8d2d109ea0755f 306 SUPERFAMILY SSF56349 12 296 5.3E-55 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1001000 5f0c5a3397e0da549f8d2d109ea0755f 306 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 13 303 54.45 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MADE_1001000 5f0c5a3397e0da549f8d2d109ea0755f 306 Pfam PF00589 Phage integrase family 118 289 8.1E-45 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1001000 5f0c5a3397e0da549f8d2d109ea0755f 306 Gene3D G3DSA:1.10.443.10 115 297 4.2E-56 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1001000 5f0c5a3397e0da549f8d2d109ea0755f 306 Gene3D G3DSA:1.10.150.130 11 103 4.4E-17 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1001000 5f0c5a3397e0da549f8d2d109ea0755f 306 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 15 93 9.7E-16 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MADE_1001000 5f0c5a3397e0da549f8d2d109ea0755f 306 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 17 305 2.6E-102 T 13-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 MADE_1002410 b9f30609ae8609c9abd85dce82c1351a 239 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 191 233 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MADE_1002410 b9f30609ae8609c9abd85dce82c1351a 239 SMART SM00342 154 237 2.8E-21 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1002410 b9f30609ae8609c9abd85dce82c1351a 239 Gene3D G3DSA:1.10.10.60 135 239 1.9E-22 T 13-10-2018 MADE_1002410 b9f30609ae8609c9abd85dce82c1351a 239 SUPERFAMILY SSF46689 137 188 1.7E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1002410 b9f30609ae8609c9abd85dce82c1351a 239 SUPERFAMILY SSF46689 191 238 9.41E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1002410 b9f30609ae8609c9abd85dce82c1351a 239 Pfam PF12833 Helix-turn-helix domain 160 238 9.8E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SUPERFAMILY SSF52540 360 481 5.02E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Gene3D G3DSA:3.40.50.11180 30 344 1.6E-119 T 13-10-2018 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Gene3D G3DSA:3.30.2060.10 139 224 1.6E-119 T 13-10-2018 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Gene3D G3DSA:2.30.30.840 498 556 1.3E-232 T 13-10-2018 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SUPERFAMILY SSF143517 1010 1161 3.14E-41 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Gene3D G3DSA:3.90.1150.50 1019 1164 2.1E-45 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Gene3D G3DSA:3.40.50.11140 365 467 7.9E-11 T 13-10-2018 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Gene3D G3DSA:3.40.50.300 493 1005 1.3E-232 T 13-10-2018 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SUPERFAMILY SSF52540 18 350 3.72E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SUPERFAMILY SSF141259 485 561 7.59E-23 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SMART SM00487 615 805 5.7E-34 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SMART SM00490 842 925 1.3E-15 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Pfam PF00270 DEAD/DEAH box helicase 620 780 1.1E-20 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 38 1142 27.745 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 156 1096 0.0 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Gene3D G3DSA:3.40.50.300 557 796 1.3E-232 T 13-10-2018 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Pfam PF03461 TRCF domain 1024 1115 1.0E-28 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Pfam PF00271 Helicase conserved C-terminal domain 822 924 2.0E-15 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SUPERFAMILY SSF52540 538 798 5.93E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SUPERFAMILY SSF52540 798 1005 4.35E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SMART SM01058 494 591 2.2E-46 T 13-10-2018 IPR003711 CarD-like/TRCF domain MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 Pfam PF02559 CarD-like/TRCF domain 495 590 1.4E-24 T 13-10-2018 IPR003711 CarD-like/TRCF domain MADE_1008320 ae95a439f8b5cb5152215d7aeae3c039 1165 SMART SM00982 1023 1123 5.0E-49 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 MADE_1002610 b9055f3ed93bc4c6713cc73a6bfc7d02 285 Gene3D G3DSA:1.20.1050.10 134 250 1.9E-105 T 13-10-2018 MADE_1002610 b9055f3ed93bc4c6713cc73a6bfc7d02 285 SUPERFAMILY SSF52833 41 132 2.49E-16 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1002610 b9055f3ed93bc4c6713cc73a6bfc7d02 285 SUPERFAMILY SSF47616 118 259 6.96E-33 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1002610 b9055f3ed93bc4c6713cc73a6bfc7d02 285 Pfam PF02798 Glutathione S-transferase, N-terminal domain 68 128 6.6E-7 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1002610 b9055f3ed93bc4c6713cc73a6bfc7d02 285 Pfam PF13410 Glutathione S-transferase, C-terminal domain 178 245 3.1E-8 T 13-10-2018 MADE_1002610 b9055f3ed93bc4c6713cc73a6bfc7d02 285 Gene3D G3DSA:3.40.30.10 19 256 1.9E-105 T 13-10-2018 MADE_1015835 c796d71ce3bef39610205373555dbf31 452 Gene3D G3DSA:3.30.9.10 135 360 1.1E-57 T 13-10-2018 MADE_1015835 c796d71ce3bef39610205373555dbf31 452 SUPERFAMILY SSF51905 20 412 9.5E-37 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1015835 c796d71ce3bef39610205373555dbf31 452 Gene3D G3DSA:3.50.50.60 41 408 1.1E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1015835 c796d71ce3bef39610205373555dbf31 452 Pfam PF01266 FAD dependent oxidoreductase 41 409 3.3E-43 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 SUPERFAMILY SSF57783 817 872 2.04E-20 T 13-10-2018 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 SMART SM00436 140 228 9.2E-48 T 13-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Gene3D G3DSA:3.30.65.10 753 815 3.7E-31 T 13-10-2018 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Gene3D G3DSA:3.30.65.10 704 752 1.4E-5 T 13-10-2018 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Gene3D G3DSA:2.20.25.10 816 875 3.4E-28 T 13-10-2018 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Gene3D G3DSA:1.10.460.10 172 579 3.7E-164 T 13-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Gene3D G3DSA:2.70.20.10 220 481 3.7E-164 T 13-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 SUPERFAMILY SSF56712 3 617 2.75E-203 T 13-10-2018 IPR023405 DNA topoisomerase, type IA, core domain MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 113 126 1.6E-37 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 1.6E-37 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 198 216 1.6E-37 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 498 512 1.6E-37 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 1.6E-37 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Gene3D G3DSA:1.10.290.10 287 411 3.7E-164 T 13-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 SUPERFAMILY SSF57783 708 751 1.36E-6 T 13-10-2018 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 SMART SM00493 3 139 1.2E-32 T 13-10-2018 IPR006171 TOPRIM domain MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Pfam PF01131 DNA topoisomerase 164 572 2.2E-132 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 SMART SM00437 279 535 2.8E-120 T 13-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 316 330 - T 13-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Pfam PF08272 Topoisomerase I zinc-ribbon-like 832 872 3.1E-22 T 13-10-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Pfam PF08272 Topoisomerase I zinc-ribbon-like 766 801 2.5E-11 T 13-10-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 SUPERFAMILY SSF57783 752 815 3.06E-19 T 13-10-2018 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Pfam PF01751 Toprim domain 5 149 2.4E-32 T 13-10-2018 IPR006171 TOPRIM domain MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 643 4.2E-252 T 13-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Gene3D G3DSA:3.40.50.140 1 170 1.7E-65 T 13-10-2018 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 740 55.702 T 13-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 717 752 3.2E-10 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MADE_000001021585 5512cc6cfbce6ff51236fe2f5c85c617 886 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 605 630 1.3E-5 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 PIRSF PIRSF006621 1 328 6.2E-109 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 49.571 T 13-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 SUPERFAMILY SSF51395 10 318 8.42E-93 T 13-10-2018 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 Gene3D G3DSA:1.10.1200.80 252 327 1.3E-7 T 13-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 Pfam PF01207 Dihydrouridine synthase (Dus) 13 318 7.4E-117 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 Gene3D G3DSA:3.20.20.70 6 249 4.0E-81 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 319 1.7E-135 T 13-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 MADE_1019730 9a061e30729960b13fc8ff5677bb530e 332 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 Gene3D G3DSA:1.10.10.160 108 181 2.6E-93 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 1 669 39.406 T 13-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 Gene3D G3DSA:3.40.50.300 4 266 2.6E-93 T 13-10-2018 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 Gene3D G3DSA:3.40.50.300 275 633 3.7E-121 T 13-10-2018 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 Gene3D G3DSA:1.10.486.10 377 540 3.7E-121 T 13-10-2018 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 Pfam PF13361 UvrD-like helicase C-terminal domain 271 614 4.7E-68 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 2 668 0.0 T 13-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 265 2.5E-73 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MADE_1000365 020688f43d88ae2cbc46b4bf40fdca0e 671 SUPERFAMILY SSF52540 1 640 4.31E-158 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 Gene3D G3DSA:3.40.50.720 2 257 3.5E-53 T 13-10-2018 MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 Pfam PF00106 short chain dehydrogenase 8 188 9.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 161 0.0091 T 13-10-2018 MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 SUPERFAMILY SSF51735 2 254 1.02E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.0E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.0E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.0E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1004075 a1ecf50cb6068f4b3f0440221b74fdb3 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.0E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013315 0e487879bb240213ddbe6b1b1594c217 121 SUPERFAMILY SSF49503 4 119 1.7E-34 T 13-10-2018 IPR008972 Cupredoxin MADE_1013315 0e487879bb240213ddbe6b1b1594c217 121 Gene3D G3DSA:2.60.40.420 1 107 1.9E-9 T 13-10-2018 IPR008972 Cupredoxin MADE_1013315 0e487879bb240213ddbe6b1b1594c217 121 Pfam PF08985 DP-EP family 10 118 1.7E-23 T 13-10-2018 IPR015078 DP-EP family MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 Pfam PF00669 Bacterial flagellin N-terminal helical region 25 148 1.0E-21 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 Gene3D G3DSA:1.20.1330.10 187 224 6.4E-8 T 13-10-2018 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 Gene3D G3DSA:1.20.58.1830 26 41 1.6E-38 T 13-10-2018 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 Pfam PF00700 Bacterial flagellin C-terminal helical region 194 278 1.6E-11 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 SUPERFAMILY SSF64518 26 268 4.58E-56 T 13-10-2018 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 PRINTS PR00207 Flagellin signature 45 62 6.7E-14 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 PRINTS PR00207 Flagellin signature 119 142 6.7E-14 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 PRINTS PR00207 Flagellin signature 84 103 6.7E-14 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 Gene3D G3DSA:1.10.8.410 227 279 5.3E-8 T 13-10-2018 MADE_1005875 ed483cc7b0a739972c38d969dc69bc31 279 Gene3D G3DSA:1.20.1330.10 53 173 1.6E-38 T 13-10-2018 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Gene3D G3DSA:2.20.25.90 16 69 4.8E-13 T 13-10-2018 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Gene3D G3DSA:3.40.228.10 148 349 2.3E-167 T 13-10-2018 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Gene3D G3DSA:2.40.40.20 590 727 3.1E-29 T 13-10-2018 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 SUPERFAMILY SSF50692 575 723 1.88E-31 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 16 67 3.3E-14 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 SUPERFAMILY SSF53706 14 589 3.66E-174 T 13-10-2018 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Pfam PF01568 Molydopterin dinucleotide binding domain 603 716 3.1E-20 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 PIRSF PIRSF036643 1 745 3.7E-143 T 13-10-2018 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Gene3D G3DSA:3.40.50.740 83 553 2.3E-167 T 13-10-2018 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Pfam PF00384 Molybdopterin oxidoreductase 84 496 1.7E-79 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Pfam PF04324 BFD-like [2Fe-2S] binding domain 887 932 3.6E-10 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 SMART SM00926 13 71 5.1E-10 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1003705 6db81e86d1d37b225f747f01a89075e4 942 Gene3D G3DSA:1.10.10.1100 887 939 3.9E-11 T 13-10-2018 MADE_1001970 c4aeed291b22c580571171255e39f87d 604 SUPERFAMILY SSF49503 171 382 3.06E-54 T 13-10-2018 IPR008972 Cupredoxin MADE_1001970 c4aeed291b22c580571171255e39f87d 604 Pfam PF00394 Multicopper oxidase 174 345 2.2E-30 T 13-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 MADE_1001970 c4aeed291b22c580571171255e39f87d 604 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 9 603 3.2E-241 T 13-10-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 MADE_1001970 c4aeed291b22c580571171255e39f87d 604 Pfam PF07732 Multicopper oxidase 66 165 7.2E-37 T 13-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 MADE_1001970 c4aeed291b22c580571171255e39f87d 604 Gene3D G3DSA:2.60.40.420 42 164 1.8E-36 T 13-10-2018 IPR008972 Cupredoxin MADE_1001970 c4aeed291b22c580571171255e39f87d 604 SUPERFAMILY SSF49503 449 603 3.32E-36 T 13-10-2018 IPR008972 Cupredoxin MADE_1001970 c4aeed291b22c580571171255e39f87d 604 ProSitePatterns PS00080 Multicopper oxidases signature 2. 586 597 - T 13-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 MADE_1001970 c4aeed291b22c580571171255e39f87d 604 Gene3D G3DSA:2.60.40.420 172 366 3.9E-40 T 13-10-2018 IPR008972 Cupredoxin MADE_1001970 c4aeed291b22c580571171255e39f87d 604 Pfam PF07731 Multicopper oxidase 488 603 1.2E-25 T 13-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 MADE_1001970 c4aeed291b22c580571171255e39f87d 604 SUPERFAMILY SSF49503 62 194 1.66E-35 T 13-10-2018 IPR008972 Cupredoxin MADE_1006055 b119224b481d9971eda8e2d578788848 277 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 45 8.0E-13 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006055 b119224b481d9971eda8e2d578788848 277 SUPERFAMILY SSF46785 1 93 9.01E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1006055 b119224b481d9971eda8e2d578788848 277 Gene3D G3DSA:1.10.10.10 1 71 1.4E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006055 b119224b481d9971eda8e2d578788848 277 Gene3D G3DSA:3.40.190.10 72 271 6.9E-67 T 13-10-2018 MADE_1006055 b119224b481d9971eda8e2d578788848 277 Pfam PF03466 LysR substrate binding domain 70 275 7.9E-35 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1006055 b119224b481d9971eda8e2d578788848 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 12 22 6.6E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006055 b119224b481d9971eda8e2d578788848 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 1 12 6.6E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006055 b119224b481d9971eda8e2d578788848 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.6E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006055 b119224b481d9971eda8e2d578788848 277 Gene3D G3DSA:3.40.190.10 145 250 6.9E-67 T 13-10-2018 MADE_1006055 b119224b481d9971eda8e2d578788848 277 SUPERFAMILY SSF53850 71 271 1.09E-35 T 13-10-2018 MADE_1016945 4c6e1c81d52eadbc1bac7d5ea2bdea38 280 Gene3D G3DSA:3.40.50.1820 1 280 1.2E-95 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1016945 4c6e1c81d52eadbc1bac7d5ea2bdea38 280 Pfam PF00756 Putative esterase 22 271 8.0E-62 T 13-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 MADE_1016945 4c6e1c81d52eadbc1bac7d5ea2bdea38 280 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 2 275 2.0E-121 T 13-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 MADE_1016945 4c6e1c81d52eadbc1bac7d5ea2bdea38 280 SUPERFAMILY SSF53474 1 277 2.13E-90 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 PIRSF PIRSF006294 1 520 8.2E-215 T 13-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 8 520 51.861 T 13-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 Pfam PF01293 Phosphoenolpyruvate carboxykinase 17 474 1.2E-194 T 13-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 244 259 - T 13-10-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 18 518 2.2E-188 T 13-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 SUPERFAMILY SSF68923 17 206 2.62E-70 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 Gene3D G3DSA:2.170.8.10 34 323 1.1E-202 T 13-10-2018 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 SUPERFAMILY SSF53795 207 518 2.56E-128 T 13-10-2018 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 Gene3D G3DSA:3.90.228.20 208 507 1.1E-202 T 13-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MADE_1019805 ed3753ecaebcbb5e6aeff4a8644c06f5 520 Gene3D G3DSA:3.40.449.10 24 207 1.1E-202 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 MADE_1009770 14cd704b5f596aec6cbe21fcc55ebc8a 153 Gene3D G3DSA:1.10.443.10 17 153 1.1E-10 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1009770 14cd704b5f596aec6cbe21fcc55ebc8a 153 Pfam PF00589 Phage integrase family 38 146 4.2E-5 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1009770 14cd704b5f596aec6cbe21fcc55ebc8a 153 SUPERFAMILY SSF56349 18 153 1.59E-15 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_000001021925 395e18c726ad2e75b115942e2199f2b4 151 Gene3D G3DSA:1.20.120.520 1 141 4.5E-9 T 13-10-2018 MADE_000001021925 395e18c726ad2e75b115942e2199f2b4 151 Pfam PF01814 Hemerythrin HHE cation binding domain 3 118 7.5E-14 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MADE_1008630 961ae00037f6970268697babc9f52eb6 268 SUPERFAMILY SSF53927 10 257 3.91E-64 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MADE_1008630 961ae00037f6970268697babc9f52eb6 268 Pfam PF02634 FdhD/NarQ family 24 256 1.6E-61 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MADE_1008630 961ae00037f6970268697babc9f52eb6 268 Gene3D G3DSA:3.40.140.10 114 265 3.7E-39 T 13-10-2018 MADE_1008630 961ae00037f6970268697babc9f52eb6 268 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 245 2.8E-44 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MADE_1008630 961ae00037f6970268697babc9f52eb6 268 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 8 262 26.846 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MADE_1008630 961ae00037f6970268697babc9f52eb6 268 Gene3D G3DSA:3.10.20.10 26 112 1.1E-5 T 13-10-2018 MADE_1008630 961ae00037f6970268697babc9f52eb6 268 PIRSF PIRSF015626 2 261 2.5E-62 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 119 1.6E-31 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 335 3.0E-134 T 13-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 PIRSF PIRSF000148 4 338 2.2E-134 T 13-10-2018 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 SUPERFAMILY SSF51735 5 159 2.33E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 Gene3D G3DSA:3.40.50.720 7 331 1.1E-145 T 13-10-2018 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 320 6.6E-61 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 SMART SM00859 6 121 1.1E-41 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 Gene3D G3DSA:3.30.360.10 130 317 1.1E-145 T 13-10-2018 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 SUPERFAMILY SSF55347 131 321 1.82E-76 T 13-10-2018 MADE_1011915 e36c5cef033a7a363bd00703b7311954 338 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 334 36.743 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1013465 d9e2c1948c248feac9110e18afec26d6 352 SUPERFAMILY SSF56112 15 341 6.83E-62 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1013465 d9e2c1948c248feac9110e18afec26d6 352 Pfam PF01636 Phosphotransferase enzyme family 36 258 3.1E-53 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase MADE_1013465 d9e2c1948c248feac9110e18afec26d6 352 Gene3D G3DSA:3.90.1200.10 113 352 2.6E-85 T 13-10-2018 MADE_1013465 d9e2c1948c248feac9110e18afec26d6 352 Gene3D G3DSA:3.30.200.20 11 112 1.1E-35 T 13-10-2018 MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SMART SM00634 554 647 5.1E-5 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SMART SM00634 267 359 0.039 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SMART SM00634 460 541 0.031 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SMART SM00634 365 450 3.1E-6 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SMART SM00634 58 143 0.19 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SMART SM00634 169 253 0.091 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Gene3D G3DSA:2.60.40.10 544 649 7.9E-10 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Gene3D G3DSA:2.60.40.10 464 543 1.7E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SUPERFAMILY SSF49373 568 644 7.06E-9 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SUPERFAMILY SSF49373 378 451 5.3E-12 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Gene3D G3DSA:2.60.40.10 359 452 3.2E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Gene3D G3DSA:2.60.40.10 149 255 3.7E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Gene3D G3DSA:2.60.40.10 259 358 7.6E-8 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Gene3D G3DSA:2.60.40.10 42 148 3.5E-9 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SUPERFAMILY SSF49373 68 143 9.42E-9 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Pfam PF02369 Bacterial Ig-like domain (group 1) 371 448 3.7E-8 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 Pfam PF02369 Bacterial Ig-like domain (group 1) 566 646 3.2E-10 T 13-10-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SUPERFAMILY SSF49373 470 538 2.94E-11 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SUPERFAMILY SSF49373 268 362 6.8E-10 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments MADE_000001021570 1a615a1c29136db4a1da690d43d11e02 845 SUPERFAMILY SSF49373 176 252 3.66E-6 T 13-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 SMART SM00357 6 70 3.1E-30 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 13-10-2018 IPR019844 Cold-shock conserved site MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 SUPERFAMILY SSF50249 4 69 1.45E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 1.2E-30 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 PIRSF PIRSF002599 1 70 2.0E-25 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 Gene3D G3DSA:2.40.50.140 2 68 2.6E-30 T 13-10-2018 MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 PRINTS PR00050 Cold shock protein signature 43 61 6.9E-18 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 PRINTS PR00050 Cold shock protein signature 28 37 6.9E-18 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1006615 9340a134bc5c75c637dea7dc9b2a7f4a 70 PRINTS PR00050 Cold shock protein signature 7 22 6.9E-18 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1013175 a27c94291194d1e38662a34430ea35e7 368 Gene3D G3DSA:3.40.50.2000 167 349 9.3E-76 T 13-10-2018 MADE_1013175 a27c94291194d1e38662a34430ea35e7 368 Pfam PF13439 Glycosyltransferase Family 4 12 167 6.7E-23 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1013175 a27c94291194d1e38662a34430ea35e7 368 Pfam PF00534 Glycosyl transferases group 1 183 344 3.9E-36 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1013175 a27c94291194d1e38662a34430ea35e7 368 SUPERFAMILY SSF53756 3 367 8.57E-81 T 13-10-2018 MADE_1013175 a27c94291194d1e38662a34430ea35e7 368 Gene3D G3DSA:3.40.50.2000 12 360 9.3E-76 T 13-10-2018 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Gene3D G3DSA:3.40.1440.10 5 101 1.8E-33 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Pfam PF02151 UvrB/uvrC motif 204 237 1.4E-12 T 13-10-2018 IPR001943 UVR domain GO:0005515 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 SMART SM00278 551 570 3.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 SMART SM00278 583 602 14.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Gene3D G3DSA:3.30.420.340 376 547 8.0E-47 T 13-10-2018 IPR038476 UvrC homology region 2 superfamily MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 SUPERFAMILY SSF46600 189 242 7.85E-15 T 13-10-2018 IPR036876 UVR domain superfamily MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Pfam PF01541 GIY-YIG catalytic domain 17 92 1.2E-10 T 13-10-2018 IPR000305 GIY-YIG endonuclease MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Pfam PF14520 Helix-hairpin-helix domain 552 603 5.3E-7 T 13-10-2018 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Gene3D G3DSA:1.10.150.20 550 605 2.1E-22 T 13-10-2018 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 SUPERFAMILY SSF82771 16 99 3.4E-24 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 SMART SM00465 16 97 9.6E-23 T 13-10-2018 IPR000305 GIY-YIG endonuclease MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Hamap MF_00203 UvrABC system protein C [uvrC]. 3 602 28.517 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 383 537 2.2E-47 T 13-10-2018 IPR001162 UvrC family homology region MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 9 584 2.8E-210 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 SUPERFAMILY SSF47781 501 604 6.99E-21 T 13-10-2018 IPR010994 RuvA domain 2-like MADE_1010575 9a5b7107124e595b579e86e9d5c6be82 605 Gene3D G3DSA:4.10.860.10 199 239 5.3E-5 T 13-10-2018 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Pfam PF00360 Phytochrome region 327 499 9.9E-37 T 13-10-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Pfam PF00072 Response regulator receiver domain 741 846 4.0E-7 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 SUPERFAMILY SSF55781 127 311 9.81E-50 T 13-10-2018 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 SUPERFAMILY SSF55781 321 500 2.26E-37 T 13-10-2018 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 SUPERFAMILY SSF55785 13 122 1.24E-22 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Gene3D G3DSA:3.30.450.270 316 490 9.8E-139 T 13-10-2018 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 SMART SM00448 738 846 1.4E-4 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 SUPERFAMILY SSF52172 741 849 1.17E-13 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Pfam PF01590 GAF domain 145 308 8.2E-15 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Gene3D G3DSA:3.30.450.40 14 473 9.8E-139 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Pfam PF07536 HWE histidine kinase 521 602 4.9E-19 T 13-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Gene3D G3DSA:3.30.450.20 19 248 9.8E-139 T 13-10-2018 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 SMART SM00911 521 602 3.1E-19 T 13-10-2018 IPR011102 Signal transduction histidine kinase, HWE region GO:0004673 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 SMART SM00065 144 317 3.7E-4 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 PRINTS PR01033 Phytochrome signature 426 445 1.1E-15 T 13-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 PRINTS PR01033 Phytochrome signature 460 478 1.1E-15 T 13-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 PRINTS PR01033 Phytochrome signature 159 178 1.1E-15 T 13-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 PRINTS PR01033 Phytochrome signature 245 266 1.1E-15 T 13-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 PRINTS PR01033 Phytochrome signature 343 363 1.1E-15 T 13-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Pfam PF08446 PAS fold 15 120 2.3E-11 T 13-10-2018 IPR013654 PAS fold-2 GO:0006355 MADE_1013275 75d2bfbdc307e4bdd659cbbf2f0923da 853 Gene3D G3DSA:3.40.50.2300 736 852 6.1E-21 T 13-10-2018 MADE_1001995 9e3a43bce32c9a2b7ee7d0b60a104626 394 SUPERFAMILY SSF58104 84 322 7.06E-41 T 13-10-2018 MADE_1001995 9e3a43bce32c9a2b7ee7d0b60a104626 394 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 175 307 1.2E-26 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1001995 9e3a43bce32c9a2b7ee7d0b60a104626 394 Gene3D G3DSA:1.10.287.950 70 372 1.4E-42 T 13-10-2018 MADE_1001995 9e3a43bce32c9a2b7ee7d0b60a104626 394 SMART SM00283 93 349 3.3E-12 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1010215 a830cea2fa018a05384275d16f053ca7 512 Gene3D G3DSA:1.10.10.1710 443 512 2.1E-26 T 13-10-2018 MADE_1010215 a830cea2fa018a05384275d16f053ca7 512 SUPERFAMILY SSF48173 229 490 4.58E-59 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 MADE_1010215 a830cea2fa018a05384275d16f053ca7 512 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 5 227 2.3E-81 T 13-10-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein MADE_1010215 a830cea2fa018a05384275d16f053ca7 512 Gene3D G3DSA:3.40.50.620 6 229 4.0E-123 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1010215 a830cea2fa018a05384275d16f053ca7 512 Gene3D G3DSA:1.10.579.10 322 442 4.3E-52 T 13-10-2018 MADE_1010215 a830cea2fa018a05384275d16f053ca7 512 Gene3D G3DSA:1.25.40.80 132 318 4.0E-123 T 13-10-2018 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 Pfam PF00717 Peptidase S24-like 81 162 7.6E-23 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 ProSitePatterns PS00760 Signal peptidases I lysine active site. 141 153 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 SUPERFAMILY SSF51306 73 299 1.06E-67 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 Gene3D G3DSA:2.10.109.10 73 273 7.0E-76 T 13-10-2018 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 Gene3D G3DSA:2.170.230.10 150 232 7.0E-76 T 13-10-2018 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 151 1.3E-26 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 233 252 1.3E-26 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 91 1.3E-26 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 ProSitePatterns PS00761 Signal peptidases I signature 3. 238 251 - T 13-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 62 273 1.4E-46 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 Pfam PF10502 Signal peptidase, peptidase S26 230 270 2.7E-5 T 13-10-2018 IPR019533 Peptidase S26 MADE_1012520 9f0427d7584c6ed6652847c9d436fd49 300 ProSitePatterns PS00501 Signal peptidases I serine active site. 84 91 - T 13-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 MADE_1001310 133b61da515edea51dbb823bf7beff4d 196 Hamap MF_00528 Septum formation protein Maf [maf]. 4 196 30.43 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1001310 133b61da515edea51dbb823bf7beff4d 196 Gene3D G3DSA:3.90.950.10 1 196 1.6E-62 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_1001310 133b61da515edea51dbb823bf7beff4d 196 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 189 1.4E-48 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1001310 133b61da515edea51dbb823bf7beff4d 196 Pfam PF02545 Maf-like protein 5 191 4.9E-53 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1001310 133b61da515edea51dbb823bf7beff4d 196 SUPERFAMILY SSF52972 2 191 1.31E-57 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_1001310 133b61da515edea51dbb823bf7beff4d 196 PIRSF PIRSF006305 1 195 2.1E-50 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1005600 2bbadc835b2f0c1499a0c38479181f6c 140 SMART SM00422 23 92 1.3E-10 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005600 2bbadc835b2f0c1499a0c38479181f6c 140 Pfam PF13411 MerR HTH family regulatory protein 25 91 1.3E-12 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005600 2bbadc835b2f0c1499a0c38479181f6c 140 SUPERFAMILY SSF46955 25 126 9.89E-19 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1005600 2bbadc835b2f0c1499a0c38479181f6c 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 59 79 7.3E-6 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005600 2bbadc835b2f0c1499a0c38479181f6c 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 24 35 7.3E-6 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005600 2bbadc835b2f0c1499a0c38479181f6c 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 35 48 7.3E-6 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005600 2bbadc835b2f0c1499a0c38479181f6c 140 Gene3D G3DSA:1.10.1660.10 25 137 4.6E-20 T 13-10-2018 MADE_1009985 d78b88d844c3d285b91b8155c61e8c4e 498 Pfam PF00128 Alpha amylase, catalytic domain 36 234 4.3E-11 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009985 d78b88d844c3d285b91b8155c61e8c4e 498 PIRSF PIRSF003059 1 493 1.3E-149 T 13-10-2018 IPR016377 Sucrose/Glucosylglycerate phosphorylase-related MADE_1009985 d78b88d844c3d285b91b8155c61e8c4e 498 SUPERFAMILY SSF51445 4 439 2.91E-74 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1009985 d78b88d844c3d285b91b8155c61e8c4e 498 Gene3D G3DSA:3.20.20.80 9 420 4.4E-129 T 13-10-2018 MADE_1009985 d78b88d844c3d285b91b8155c61e8c4e 498 SMART SM00642 8 437 3.3E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009985 d78b88d844c3d285b91b8155c61e8c4e 498 Gene3D G3DSA:3.90.400.10 90 180 4.4E-129 T 13-10-2018 MADE_1009985 d78b88d844c3d285b91b8155c61e8c4e 498 TIGRFAM TIGR03852 sucrose_gtfA: sucrose phosphorylase 5 480 2.5E-128 T 13-10-2018 IPR022527 Sucrose phosphorylase GO:0004645|GO:0044262 MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 Gene3D G3DSA:3.40.30.10 1 84 3.6E-27 T 13-10-2018 MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 PRINTS PR00160 Glutaredoxin signature 61 74 8.2E-16 T 13-10-2018 IPR014025 Glutaredoxin subgroup MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 PRINTS PR00160 Glutaredoxin signature 4 22 8.2E-16 T 13-10-2018 IPR014025 Glutaredoxin subgroup MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 PRINTS PR00160 Glutaredoxin signature 47 60 8.2E-16 T 13-10-2018 IPR014025 Glutaredoxin subgroup MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 SUPERFAMILY SSF52833 1 84 2.96E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 1.6E-35 T 13-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 MADE_1002715 c6709f279162cbf45a0f9458e954c080 86 Pfam PF00462 Glutaredoxin 4 64 3.5E-21 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 SMART SM00842 12 179 0.005 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 SUPERFAMILY SSF53067 12 178 7.3E-10 T 13-10-2018 MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 Gene3D G3DSA:3.30.1490.300 88 147 1.4E-68 T 13-10-2018 MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 Pfam PF11104 Type IV pilus assembly protein PilM; 14 350 2.9E-102 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 12 350 3.8E-73 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 PIRSF PIRSF019169 1 351 4.8E-96 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 Gene3D G3DSA:3.30.420.40 13 348 1.4E-68 T 13-10-2018 MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 SUPERFAMILY SSF53067 189 349 9.15E-12 T 13-10-2018 MADE_1002590 31b725b77edd1faf1924f55fd42819f0 355 Gene3D G3DSA:3.30.420.40 187 314 1.4E-68 T 13-10-2018 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 SUPERFAMILY SSF52440 5 123 8.06E-40 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 Gene3D G3DSA:3.30.470.20 116 296 2.7E-112 T 13-10-2018 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 297 2.5E-71 T 13-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 Gene3D G3DSA:3.30.1490.20 138 202 2.7E-112 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 313 2.2E-124 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 Hamap MF_00162 Glutathione synthetase [gshB]. 1 316 152.023 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 Gene3D G3DSA:3.40.50.20 8 115 2.7E-112 T 13-10-2018 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 SUPERFAMILY SSF56059 124 313 1.86E-53 T 13-10-2018 MADE_1015320 73b1dc3f42aae4a82f093e69b3766d40 316 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 121 2.6E-41 T 13-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MADE_000001022360 4721d434ffa339b44323b2b85f0012a5 423 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 16 355 1.0E-124 T 13-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MADE_000001022360 4721d434ffa339b44323b2b85f0012a5 423 Pfam PF08388 Group II intron, maturase-specific domain 293 367 2.2E-17 T 13-10-2018 IPR013597 Group II intron, maturase-specific MADE_000001022360 4721d434ffa339b44323b2b85f0012a5 423 SUPERFAMILY SSF56672 21 367 1.14E-53 T 13-10-2018 MADE_000001022360 4721d434ffa339b44323b2b85f0012a5 423 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 280 8.7E-44 T 13-10-2018 IPR000477 Reverse transcriptase domain MADE_1006775 97cdb80bf2df957313cbd3f973acd61c 667 Gene3D G3DSA:3.40.50.410 95 291 1.3E-28 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1006775 97cdb80bf2df957313cbd3f973acd61c 667 SUPERFAMILY SSF48452 391 481 9.39E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006775 97cdb80bf2df957313cbd3f973acd61c 667 Pfam PF00515 Tetratricopeptide repeat 437 469 1.5E-8 T 13-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 MADE_1006775 97cdb80bf2df957313cbd3f973acd61c 667 SUPERFAMILY SSF53300 99 217 1.58E-14 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1006775 97cdb80bf2df957313cbd3f973acd61c 667 Gene3D G3DSA:1.25.40.10 371 488 2.7E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006775 97cdb80bf2df957313cbd3f973acd61c 667 SMART SM00028 436 469 1.1E-7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006775 97cdb80bf2df957313cbd3f973acd61c 667 Pfam PF13519 von Willebrand factor type A domain 99 205 2.3E-13 T 13-10-2018 IPR002035 von Willebrand factor, type A MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 SUPERFAMILY SSF54919 1 140 1.7E-60 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 1.5E-41 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 1.5E-41 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 1.5E-41 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 1.5E-41 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 1.5E-41 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 SMART SM00562 3 140 8.2E-88 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 Gene3D G3DSA:3.30.70.141 1 143 2.6E-59 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 13-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 36.874 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1012870 1640937dfb0f69148fd97bd69af16902 143 Pfam PF00334 Nucleoside diphosphate kinase 4 138 6.3E-58 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 MADE_1004430 12ed1d2e7b9377058e55f68105d5c63f 218 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 20 216 2.2E-62 T 13-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 MADE_1004430 12ed1d2e7b9377058e55f68105d5c63f 218 Pfam PF03006 Haemolysin-III related 17 210 1.3E-35 T 13-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 SUPERFAMILY SSF52935 326 477 1.96E-35 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 Gene3D G3DSA:3.20.20.60 3 338 2.1E-153 T 13-10-2018 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 SUPERFAMILY SSF50800 71 166 1.67E-24 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 Gene3D G3DSA:3.40.1380.20 339 473 2.1E-153 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 477 2.8E-165 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 Pfam PF00224 Pyruvate kinase, barrel domain 3 341 1.2E-127 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 Gene3D G3DSA:2.40.33.10 71 169 2.1E-153 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 360 475 2.1E-28 T 13-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 PRINTS PR01050 Pyruvate kinase family signature 60 76 5.4E-52 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 PRINTS PR01050 Pyruvate kinase family signature 187 201 5.4E-52 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 PRINTS PR01050 Pyruvate kinase family signature 297 315 5.4E-52 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 PRINTS PR01050 Pyruvate kinase family signature 316 332 5.4E-52 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 PRINTS PR01050 Pyruvate kinase family signature 247 271 5.4E-52 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 PRINTS PR01050 Pyruvate kinase family signature 272 296 5.4E-52 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 PRINTS PR01050 Pyruvate kinase family signature 220 246 5.4E-52 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 MADE_1011715 e74dd64f4da77547d51cc72bce6abd95 478 SUPERFAMILY SSF51621 2 342 8.64E-86 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MADE_1008635 7d87fa5e5397b596764561e329257e10 779 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 14 762 1.8E-287 T 13-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 MADE_1008635 7d87fa5e5397b596764561e329257e10 779 SUPERFAMILY SSF50692 645 768 2.71E-17 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MADE_1008635 7d87fa5e5397b596764561e329257e10 779 PIRSF PIRSF000144 1 767 0.0 T 13-10-2018 MADE_1008635 7d87fa5e5397b596764561e329257e10 779 SUPERFAMILY SSF53706 48 631 2.22E-146 T 13-10-2018 MADE_1008635 7d87fa5e5397b596764561e329257e10 779 Gene3D G3DSA:3.40.228.10 186 413 5.1E-71 T 13-10-2018 MADE_1008635 7d87fa5e5397b596764561e329257e10 779 Pfam PF00384 Molybdopterin oxidoreductase 110 495 3.1E-24 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1008635 7d87fa5e5397b596764561e329257e10 779 Gene3D G3DSA:3.40.50.740 120 585 5.1E-71 T 13-10-2018 MADE_1008635 7d87fa5e5397b596764561e329257e10 779 Pfam PF01568 Molydopterin dinucleotide binding domain 649 736 1.0E-9 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 Pfam PF00232 Glycosyl hydrolase family 1 12 442 2.8E-143 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 349 357 - T 13-10-2018 IPR018120 Glycoside hydrolase family 1, active site MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 TIGRFAM TIGR03356 BGL: beta-galactosidase 14 436 2.4E-178 T 13-10-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092|MetaCyc: PWY-7913 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 SUPERFAMILY SSF51445 13 443 7.46E-152 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 Gene3D G3DSA:3.20.20.80 4 445 1.9E-158 T 13-10-2018 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 349 357 2.1E-23 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 2.1E-23 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 380 2.1E-23 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 407 2.1E-23 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MADE_1019040 7cf3f77c0b61984e31f991df9e06121a 452 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 426 2.1E-23 T 13-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 SMART SM00354 1 71 1.5E-25 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 Gene3D G3DSA:3.40.50.2300 160 289 3.5E-79 T 13-10-2018 MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 SUPERFAMILY SSF47413 1 59 4.59E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 Gene3D G3DSA:3.40.50.2300 64 308 3.5E-79 T 13-10-2018 MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 8.1E-19 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 Gene3D G3DSA:1.10.260.40 1 58 2.2E-20 T 13-10-2018 MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 SUPERFAMILY SSF53822 63 330 1.1E-80 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1002085 60b4d6214aada9d9aa78b59f3a28d553 334 Pfam PF13377 Periplasmic binding protein-like domain 168 329 2.4E-45 T 13-10-2018 MADE_1019600 bf9cb0eb947d5596084f6ef808837bfc 79 SUPERFAMILY SSF89447 3 67 9.42E-7 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily MADE_1019600 bf9cb0eb947d5596084f6ef808837bfc 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 53 3.9E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MADE_1019600 bf9cb0eb947d5596084f6ef808837bfc 79 Gene3D G3DSA:2.10.260.10 1 77 4.3E-28 T 13-10-2018 MADE_1000745 a98db4791f5bcc768675f0828171e9a0 353 Pfam PF00990 Diguanylate cyclase, GGDEF domain 194 350 7.8E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_1000745 a98db4791f5bcc768675f0828171e9a0 353 SMART SM00267 184 352 2.5E-53 T 13-10-2018 IPR000160 GGDEF domain MADE_1000745 a98db4791f5bcc768675f0828171e9a0 353 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 192 352 1.5E-48 T 13-10-2018 IPR000160 GGDEF domain MADE_1000745 a98db4791f5bcc768675f0828171e9a0 353 SUPERFAMILY SSF55073 199 352 1.6E-44 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1000745 a98db4791f5bcc768675f0828171e9a0 353 Gene3D G3DSA:3.30.70.270 189 353 2.7E-51 T 13-10-2018 MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 SUPERFAMILY SSF53335 79 391 1.29E-69 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 SUPERFAMILY SSF88697 4 72 6.13E-16 T 13-10-2018 IPR015947 PUA-like superfamily MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 Hamap MF_01857 Ribosomal RNA large subunit methyltransferase I [rlmI]. 1 395 69.379 T 13-10-2018 IPR023542 rRNA large subunit methyltransferase I GO:0008649 MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 Gene3D G3DSA:3.40.50.150 181 395 3.5E-67 T 13-10-2018 MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 SMART SM00359 3 88 7.2E-10 T 13-10-2018 IPR002478 PUA domain GO:0003723 MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 Gene3D G3DSA:3.30.750.80 73 180 1.3E-34 T 13-10-2018 MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 Gene3D G3DSA:2.30.130.10 1 72 7.4E-29 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 MADE_1008550 54cf965c6b2362dab43fafa7cc5925b2 397 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 343 4.9E-26 T 13-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MADE_1003385 4daae6cb0e874aac761d02e5f1da31e4 238 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 227 3.1E-79 T 13-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MADE_1003385 4daae6cb0e874aac761d02e5f1da31e4 238 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 5 225 43.07 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MADE_1003385 4daae6cb0e874aac761d02e5f1da31e4 238 SUPERFAMILY SSF53448 6 226 4.38E-63 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1003385 4daae6cb0e874aac761d02e5f1da31e4 238 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 224 1.0E-70 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 MADE_1003385 4daae6cb0e874aac761d02e5f1da31e4 238 Gene3D G3DSA:3.90.550.10 2 232 2.6E-75 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1020175 689b83c20de146594cc10a582a91eeca 170 Gene3D G3DSA:1.10.10.10 100 167 4.0E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1020175 689b83c20de146594cc10a582a91eeca 170 Gene3D G3DSA:1.10.1740.10 4 99 3.2E-14 T 13-10-2018 MADE_1020175 689b83c20de146594cc10a582a91eeca 170 Pfam PF08281 Sigma-70, region 4 112 161 5.9E-11 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1020175 689b83c20de146594cc10a582a91eeca 170 Pfam PF04542 Sigma-70 region 2 11 75 5.0E-12 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1020175 689b83c20de146594cc10a582a91eeca 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 163 1.1E-24 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1020175 689b83c20de146594cc10a582a91eeca 170 SUPERFAMILY SSF88659 107 165 2.4E-11 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1020175 689b83c20de146594cc10a582a91eeca 170 SUPERFAMILY SSF88946 7 81 5.49E-14 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1002325 c59228acad145070eb5be26687417bc8 367 Gene3D G3DSA:3.40.50.2000 160 343 8.4E-58 T 13-10-2018 MADE_1002325 c59228acad145070eb5be26687417bc8 367 Gene3D G3DSA:3.40.50.2000 39 356 8.4E-58 T 13-10-2018 MADE_1002325 c59228acad145070eb5be26687417bc8 367 Pfam PF13439 Glycosyltransferase Family 4 16 162 4.7E-8 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1002325 c59228acad145070eb5be26687417bc8 367 Pfam PF00534 Glycosyl transferases group 1 177 332 3.1E-29 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1002325 c59228acad145070eb5be26687417bc8 367 SUPERFAMILY SSF53756 4 358 3.93E-65 T 13-10-2018 MADE_1018985 f755f9c45227a6ab273473b20b5033d5 360 Gene3D G3DSA:1.10.287.950 4 288 1.7E-45 T 13-10-2018 MADE_1018985 f755f9c45227a6ab273473b20b5033d5 360 Pfam PF13682 Chemoreceptor zinc-binding domain 260 326 8.0E-12 T 13-10-2018 IPR025991 Chemoreceptor zinc-binding domain MADE_1018985 f755f9c45227a6ab273473b20b5033d5 360 SMART SM00283 46 283 4.1E-22 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1018985 f755f9c45227a6ab273473b20b5033d5 360 SUPERFAMILY SSF58104 56 285 2.75E-47 T 13-10-2018 MADE_1018985 f755f9c45227a6ab273473b20b5033d5 360 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 116 253 2.6E-32 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 Gene3D G3DSA:1.20.1560.10 3 299 3.5E-26 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 7 543 6.0E-189 T 13-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 SUPERFAMILY SSF52540 308 542 1.27E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 Gene3D G3DSA:3.40.50.300 311 552 7.4E-70 T 13-10-2018 MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 Pfam PF00005 ABC transporter 335 482 9.3E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 Pfam PF00664 ABC transporter transmembrane region 14 263 3.0E-6 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 SMART SM00382 343 529 7.4E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 SUPERFAMILY SSF90123 9 309 9.42E-36 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1006960 51bb5388a2c0370b24699d89739f1a24 553 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 Pfam PF00849 RNA pseudouridylate synthase 66 202 2.7E-16 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 Pfam PF01479 S4 domain 4 47 1.0E-12 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 SUPERFAMILY SSF55120 66 240 7.2E-44 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 Gene3D G3DSA:3.10.290.10 1 58 2.2E-22 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 SUPERFAMILY SSF55174 5 95 1.62E-14 T 13-10-2018 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 SMART SM00363 3 60 1.3E-7 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 Gene3D G3DSA:3.30.70.1560 128 224 1.1E-54 T 13-10-2018 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 Gene3D G3DSA:3.30.70.580 67 232 1.1E-54 T 13-10-2018 MADE_1006925 e78ccd78c746bd460c18ca1130de294d 298 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 235 3.2E-55 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MADE_1008105 e754062f20a892e82d8765ec08aec3b4 484 SUPERFAMILY SSF51735 164 286 1.77E-7 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008105 e754062f20a892e82d8765ec08aec3b4 484 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 43 484 1.9E-165 T 13-10-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 MADE_1008105 e754062f20a892e82d8765ec08aec3b4 484 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 41 484 5.9E-149 T 13-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MADE_1008105 e754062f20a892e82d8765ec08aec3b4 484 Pfam PF13727 CoA-binding domain 81 258 1.0E-40 T 13-10-2018 MADE_1008105 e754062f20a892e82d8765ec08aec3b4 484 Gene3D G3DSA:3.40.50.720 159 283 4.0E-16 T 13-10-2018 MADE_1008105 e754062f20a892e82d8765ec08aec3b4 484 Pfam PF02397 Bacterial sugar transferase 294 476 2.0E-64 T 13-10-2018 IPR003362 Bacterial sugar transferase MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 SUPERFAMILY SSF55874 560 674 1.06E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 654 4.4E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 605 619 4.4E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 660 673 4.4E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 634 4.4E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 SMART SM00387 566 675 1.6E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 568 673 3.8E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 TIGRFAM TIGR02916 PEP_his_kin: putative PEP-CTERM system histidine kinase 5 673 3.2E-174 T 13-10-2018 IPR014265 Signal transduction histidine kinase, PEP-CTERM system, putative MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 Gene3D G3DSA:3.30.565.10 526 673 8.1E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015280 ac14728b04686f9dc7fe478683ec68e2 675 Gene3D G3DSA:1.10.287.130 469 525 8.1E-33 T 13-10-2018 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SUPERFAMILY SSF55681 467 690 2.58E-50 T 13-10-2018 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Pfam PF03483 B3/4 domain 212 385 4.6E-67 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Gene3D G3DSA:3.50.40.10 197 395 5.3E-77 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Pfam PF03147 Ferredoxin-fold anticodon binding domain 701 794 2.0E-24 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SMART SM00873 212 385 2.6E-93 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Pfam PF01588 Putative tRNA binding domain 46 145 2.6E-25 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Gene3D G3DSA:3.30.930.10 488 692 1.2E-57 T 13-10-2018 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SMART SM00896 701 794 3.5E-36 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SUPERFAMILY SSF56037 197 394 9.15E-73 T 13-10-2018 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SUPERFAMILY SSF50249 35 197 1.17E-51 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Pfam PF03484 tRNA synthetase B5 domain 406 471 5.2E-19 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SMART SM00874 403 471 6.2E-30 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SUPERFAMILY SSF46955 404 475 6.41E-20 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 SUPERFAMILY SSF54991 697 794 3.14E-27 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 794 2.7E-271 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Gene3D G3DSA:3.30.56.10 401 475 3.2E-27 T 13-10-2018 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Gene3D G3DSA:3.30.56.10 7 179 3.9E-75 T 13-10-2018 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Gene3D G3DSA:2.40.50.140 39 154 3.9E-75 T 13-10-2018 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 788 46.489 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MADE_1008280 a637c1a3eeec575457d67b37d606166c 795 Gene3D G3DSA:3.30.70.380 702 795 5.3E-27 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 MADE_1012210 5177fffafa91f10b5e37354994d04fb4 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 542 1.1E-18 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MADE_1012210 5177fffafa91f10b5e37354994d04fb4 550 Gene3D G3DSA:3.30.300.310 456 550 2.2E-30 T 13-10-2018 MADE_1012210 5177fffafa91f10b5e37354994d04fb4 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 13-10-2018 IPR020845 AMP-binding, conserved site MADE_1012210 5177fffafa91f10b5e37354994d04fb4 550 Gene3D G3DSA:3.40.50.12780 12 455 1.9E-118 T 13-10-2018 MADE_1012210 5177fffafa91f10b5e37354994d04fb4 550 SUPERFAMILY SSF56801 21 550 1.05E-148 T 13-10-2018 MADE_1012210 5177fffafa91f10b5e37354994d04fb4 550 Pfam PF00501 AMP-binding enzyme 29 459 2.0E-111 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 SUPERFAMILY SSF52540 79 349 5.48E-89 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 460 3.7E-257 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 343 8.9E-63 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 Gene3D G3DSA:3.40.50.300 77 345 7.4E-111 T 13-10-2018 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 SUPERFAMILY SSF47917 346 460 4.45E-55 T 13-10-2018 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 SUPERFAMILY SSF50615 2 76 2.2E-23 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 461 56.453 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 SMART SM00382 143 328 0.0026 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 Gene3D G3DSA:2.40.10.170 1 76 8.3E-27 T 13-10-2018 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 Gene3D G3DSA:1.10.1140.10 346 461 2.0E-59 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 74 6.4E-18 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020450 da24d0e6ee87d67014bcc982ed31e34a 461 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 334 343 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1015720 b84dce487d576805b80e5773e4498d63 419 Pfam PF00990 Diguanylate cyclase, GGDEF domain 255 405 2.0E-33 T 13-10-2018 IPR000160 GGDEF domain MADE_1015720 b84dce487d576805b80e5773e4498d63 419 Gene3D G3DSA:3.40.50.2300 1 122 2.0E-15 T 13-10-2018 MADE_1015720 b84dce487d576805b80e5773e4498d63 419 SUPERFAMILY SSF52172 1 109 7.12E-17 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015720 b84dce487d576805b80e5773e4498d63 419 SMART SM00448 2 118 1.8E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015720 b84dce487d576805b80e5773e4498d63 419 SMART SM00448 124 238 1.3E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015720 b84dce487d576805b80e5773e4498d63 419 Gene3D G3DSA:3.30.70.270 255 418 6.6E-39 T 13-10-2018 MADE_1015720 b84dce487d576805b80e5773e4498d63 419 SUPERFAMILY SSF52172 125 258 1.71E-33 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015720 b84dce487d576805b80e5773e4498d63 419 Gene3D G3DSA:3.40.50.2300 124 254 4.6E-32 T 13-10-2018 MADE_1015720 b84dce487d576805b80e5773e4498d63 419 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 253 408 3.9E-36 T 13-10-2018 IPR000160 GGDEF domain MADE_1015720 b84dce487d576805b80e5773e4498d63 419 SMART SM00267 244 409 6.6E-42 T 13-10-2018 IPR000160 GGDEF domain MADE_1015720 b84dce487d576805b80e5773e4498d63 419 SUPERFAMILY SSF55073 260 408 6.91E-32 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1015720 b84dce487d576805b80e5773e4498d63 419 Pfam PF00072 Response regulator receiver domain 4 105 1.2E-9 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015720 b84dce487d576805b80e5773e4498d63 419 Pfam PF00072 Response regulator receiver domain 126 234 8.5E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 Pfam PF00700 Bacterial flagellin C-terminal helical region 359 443 8.6E-11 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 Gene3D G3DSA:2.170.280.10 227 351 9.5E-26 T 13-10-2018 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 SUPERFAMILY SSF64518 3 443 3.01E-66 T 13-10-2018 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 Gene3D G3DSA:1.20.1330.10 352 403 9.5E-26 T 13-10-2018 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 Gene3D G3DSA:1.20.1330.10 41 137 1.3E-45 T 13-10-2018 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 Gene3D G3DSA:1.20.58.1830 409 443 9.5E-26 T 13-10-2018 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 Gene3D G3DSA:1.20.58.1830 18 29 1.3E-45 T 13-10-2018 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 Pfam PF00669 Bacterial flagellin N-terminal helical region 18 130 7.9E-29 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 PRINTS PR00207 Flagellin signature 107 130 2.2E-14 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 PRINTS PR00207 Flagellin signature 33 50 2.2E-14 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1013925 8fbc6a9079419ab4cf9973740d85bb3a 449 PRINTS PR00207 Flagellin signature 72 91 2.2E-14 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1009950 ddcc88eb2e99f0eddd8aeb001c246d96 531 Pfam PF00450 Serine carboxypeptidase 88 474 8.2E-15 T 13-10-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 MADE_1009950 ddcc88eb2e99f0eddd8aeb001c246d96 531 Gene3D G3DSA:3.40.50.1820 69 344 9.1E-18 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1009950 ddcc88eb2e99f0eddd8aeb001c246d96 531 SUPERFAMILY SSF53474 61 502 1.11E-78 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1009450 d036875cfd8d459c57e7e36bae5e8c31 320 Gene3D G3DSA:3.40.30.130 6 171 2.4E-65 T 13-10-2018 MADE_1009450 d036875cfd8d459c57e7e36bae5e8c31 320 Pfam PF13410 Glutathione S-transferase, C-terminal domain 196 268 2.1E-13 T 13-10-2018 MADE_1009450 d036875cfd8d459c57e7e36bae5e8c31 320 SUPERFAMILY SSF52833 31 154 3.58E-15 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1009450 d036875cfd8d459c57e7e36bae5e8c31 320 SUPERFAMILY SSF47616 175 317 3.06E-36 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1009450 d036875cfd8d459c57e7e36bae5e8c31 320 PIRSF PIRSF015753 5 317 3.8E-140 T 13-10-2018 IPR016639 Glutathione S-transferase Omega/GSH GO:0004364 MADE_1009450 d036875cfd8d459c57e7e36bae5e8c31 320 Gene3D G3DSA:1.20.1050.10 172 320 3.6E-71 T 13-10-2018 MADE_1009450 d036875cfd8d459c57e7e36bae5e8c31 320 Pfam PF13409 Glutathione S-transferase, N-terminal domain 56 151 3.9E-22 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1012905 728f29e62ba41bc57c04de7bb1312202 478 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 12 469 7.7E-196 T 13-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 MADE_1012905 728f29e62ba41bc57c04de7bb1312202 478 SUPERFAMILY SSF101960 33 475 2.75E-140 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily MADE_1012905 728f29e62ba41bc57c04de7bb1312202 478 Pfam PF01458 Uncharacterized protein family (UPF0051) 217 449 2.1E-66 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MADE_1010955 822997ed54113b2e9b84ec5037aafa23 289 Gene3D G3DSA:3.90.550.10 10 271 4.5E-39 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1010955 822997ed54113b2e9b84ec5037aafa23 289 Pfam PF12804 MobA-like NTP transferase domain 16 242 2.4E-24 T 13-10-2018 IPR025877 MobA-like NTP transferase MADE_1010955 822997ed54113b2e9b84ec5037aafa23 289 SUPERFAMILY SSF53448 14 266 1.2E-15 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1000060 0d2e0df9373e1d4c307eaea23afe635e 232 Pfam PF13489 Methyltransferase domain 81 219 8.0E-16 T 13-10-2018 MADE_1000060 0d2e0df9373e1d4c307eaea23afe635e 232 SUPERFAMILY SSF53335 75 219 5.05E-14 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1000060 0d2e0df9373e1d4c307eaea23afe635e 232 Gene3D G3DSA:3.40.50.150 59 221 1.2E-10 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Gene3D G3DSA:1.20.120.330 319 474 1.7E-50 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 SUPERFAMILY SSF81301 40 320 2.78E-72 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Gene3D G3DSA:1.20.120.1510 486 599 2.0E-27 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 38 987 17.926 T 13-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 SUPERFAMILY SSF81593 321 470 6.04E-40 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Gene3D G3DSA:1.20.120.330 855 987 5.0E-36 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Pfam PF08335 GlnD PII-uridylyltransferase 331 469 1.1E-41 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Pfam PF08335 GlnD PII-uridylyltransferase 869 964 1.8E-9 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Gene3D G3DSA:3.30.460.100 50 309 1.4E-67 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Gene3D G3DSA:3.30.460.100 600 853 1.6E-82 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 SUPERFAMILY SSF81301 563 853 1.6E-80 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 SUPERFAMILY SSF81593 857 986 1.57E-27 T 13-10-2018 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 88 308 1.4E-74 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MADE_1007420 c12bf191d4f74dab4df15588eaf6ac18 990 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 590 845 8.4E-81 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 MADE_000001021265 5dbd52f2ec7a521fc54afc88db2b4db5 119 SUPERFAMILY SSF54593 5 115 1.07E-16 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_000001021265 5dbd52f2ec7a521fc54afc88db2b4db5 119 Gene3D G3DSA:3.10.180.10 1 118 7.4E-13 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 SUPERFAMILY SSF51306 82 204 1.17E-35 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 SUPERFAMILY SSF46785 3 68 2.27E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 156 168 7.1E-13 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 128 139 7.1E-13 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 117 127 7.1E-13 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 Gene3D G3DSA:2.10.109.10 86 208 1.0E-43 T 13-10-2018 MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 Gene3D G3DSA:1.10.10.10 1 69 7.1E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 Pfam PF01726 LexA DNA binding domain 1 65 7.2E-30 T 13-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 TIGRFAM TIGR00498 lexA: repressor LexA 1 205 1.4E-79 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 Hamap MF_00015 LexA repressor [lexA]. 3 205 31.571 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 MADE_1020110 08746eef79a41fed700b38ca0966b4bd 208 Pfam PF00717 Peptidase S24-like 120 186 8.6E-15 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C MADE_1003835 3e8c03d4a52b94e83d0d3b1834d8e493 187 SMART SM00530 18 73 1.1E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1003835 3e8c03d4a52b94e83d0d3b1834d8e493 187 Gene3D G3DSA:2.60.120.10 95 187 5.3E-22 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1003835 3e8c03d4a52b94e83d0d3b1834d8e493 187 SUPERFAMILY SSF47413 12 79 2.01E-15 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1003835 3e8c03d4a52b94e83d0d3b1834d8e493 187 Gene3D G3DSA:1.10.260.40 6 90 1.9E-18 T 13-10-2018 MADE_1003835 3e8c03d4a52b94e83d0d3b1834d8e493 187 Pfam PF01381 Helix-turn-helix 20 71 1.8E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1003835 3e8c03d4a52b94e83d0d3b1834d8e493 187 SUPERFAMILY SSF51182 58 186 1.53E-14 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 Pfam PF03129 Anticodon binding domain 330 422 1.0E-11 T 13-10-2018 IPR004154 Anticodon-binding MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 Pfam PF13393 Histidyl-tRNA synthetase 10 312 1.7E-48 T 13-10-2018 MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 Gene3D G3DSA:3.30.930.10 2 322 1.3E-117 T 13-10-2018 MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 SUPERFAMILY SSF52954 330 424 7.85E-24 T 13-10-2018 MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 408 4.0E-156 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 422 33.302 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 SUPERFAMILY SSF55681 5 318 6.77E-106 T 13-10-2018 MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 Gene3D G3DSA:3.40.50.800 328 424 9.1E-24 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily MADE_1005220 2966a9a86c7141a038025dde7e9e74f8 427 PIRSF PIRSF001549 2 424 3.4E-122 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 Gene3D G3DSA:3.30.499.10 325 466 4.5E-51 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 465 59.73 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 463 1.2E-244 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 ProSitePatterns PS00450 Aconitase family signature 1. 338 354 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 SUPERFAMILY SSF53732 2 464 1.14E-161 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 Pfam PF00330 Aconitase family (aconitate hydratase) 7 456 2.2E-157 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 342 353 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 107 115 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 118 131 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 81 94 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 194 207 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 285 299 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 398 411 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 208 221 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 PRINTS PR00415 Aconitase family signature 132 147 2.9E-47 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 Gene3D G3DSA:3.30.499.20 4 285 5.5E-98 T 13-10-2018 MADE_1004695 34387448ed7ff55171c7b300abd98824 466 ProSitePatterns PS01244 Aconitase family signature 2. 398 411 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MADE_1002745 2cc0b0ceff8bede16cf42d4084ef68be 291 SUPERFAMILY SSF103481 39 137 3.79E-11 T 13-10-2018 MADE_1002745 2cc0b0ceff8bede16cf42d4084ef68be 291 SUPERFAMILY SSF103481 185 277 1.7E-11 T 13-10-2018 MADE_1002745 2cc0b0ceff8bede16cf42d4084ef68be 291 Pfam PF00892 EamA-like transporter family 9 137 5.5E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1002745 2cc0b0ceff8bede16cf42d4084ef68be 291 Pfam PF00892 EamA-like transporter family 148 274 5.6E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 Pfam PF00202 Aminotransferase class-III 45 439 9.2E-128 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 Gene3D G3DSA:3.90.1150.10 28 434 1.4E-167 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 PIRSF PIRSF000521 49 441 7.8E-29 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 31 440 2.5E-183 T 13-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 19 441 48.579 T 13-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 SUPERFAMILY SSF53383 22 441 8.72E-130 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 Gene3D G3DSA:3.40.640.10 79 349 1.4E-167 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1007250 4f6e99ba14a21c55b17a9bea105cc685 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 MADE_000001023240 69be8893c384423c8ccdc4842eba53bd 76 SUPERFAMILY SSF143120 3 44 2.62E-10 T 13-10-2018 IPR036165 YefM-like superfamily MADE_000001023240 69be8893c384423c8ccdc4842eba53bd 76 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 41 1.4E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MADE_000001023240 69be8893c384423c8ccdc4842eba53bd 76 Gene3D G3DSA:3.40.1620.10 2 38 2.3E-10 T 13-10-2018 MADE_000001023240 69be8893c384423c8ccdc4842eba53bd 76 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 40 1.8E-10 T 13-10-2018 MADE_1020410 42b3bac0ed51c99b8f8c7ae47401206f 155 Gene3D G3DSA:3.10.450.50 17 148 1.8E-13 T 13-10-2018 MADE_1020410 42b3bac0ed51c99b8f8c7ae47401206f 155 SUPERFAMILY SSF54427 17 139 1.37E-20 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1020410 42b3bac0ed51c99b8f8c7ae47401206f 155 Pfam PF13474 SnoaL-like domain 26 139 4.9E-31 T 13-10-2018 IPR037401 SnoaL-like domain MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:2.60.40.10 639 762 4.5E-28 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:3.40.50.2300 1061 1200 2.0E-20 T 13-10-2018 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF00512 His Kinase A (phospho-acceptor) domain 828 891 3.5E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SUPERFAMILY SSF63829 387 592 1.4E-17 T 13-10-2018 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF07495 Y_Y_Y domain 687 742 1.2E-15 T 13-10-2018 IPR011123 Two component regulator three Y MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:3.40.50.2300 1209 1349 1.3E-42 T 13-10-2018 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SUPERFAMILY SSF52172 1072 1195 1.99E-20 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 999 1009 6.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 981 995 6.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1040 1053 6.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1016 1034 6.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SMART SM00388 827 892 3.2E-22 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:3.30.565.10 892 1059 2.8E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SUPERFAMILY SSF63829 25 227 1.6E-13 T 13-10-2018 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:2.130.10.10 4 104 1.6E-25 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:2.130.10.10 105 327 5.7E-36 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SUPERFAMILY SSF52172 1224 1350 2.85E-37 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SUPERFAMILY SSF47384 812 893 5.49E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SMART SM00448 1226 1346 2.8E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SMART SM00448 1072 1190 8.8E-7 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SUPERFAMILY SSF63829 202 415 9.37E-12 T 13-10-2018 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:1.10.287.130 792 890 1.2E-28 T 13-10-2018 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SUPERFAMILY SSF55874 881 1052 6.16E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF07494 Two component regulator propeller 109 131 0.0012 T 13-10-2018 IPR011110 Two component regulator propeller MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF07494 Two component regulator propeller 16 35 9.0E-4 T 13-10-2018 IPR011110 Two component regulator propeller MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF07494 Two component regulator propeller 62 83 0.01 T 13-10-2018 IPR011110 Two component regulator propeller MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF07494 Two component regulator propeller 468 490 0.0036 T 13-10-2018 IPR011110 Two component regulator propeller MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Gene3D G3DSA:2.130.10.10 331 635 9.7E-52 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF00072 Response regulator receiver domain 1075 1190 2.4E-12 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF00072 Response regulator receiver domain 1228 1344 2.5E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 SMART SM00387 939 1056 7.9E-36 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1012045 5acc26a17b9eea365a43832245056cb7 1351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 940 1052 8.0E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001022865 b48d53b40a30cbb910e9a3c892bf3938 244 SMART SM00530 10 64 3.0E-4 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_000001022865 b48d53b40a30cbb910e9a3c892bf3938 244 Gene3D G3DSA:1.10.260.40 5 79 1.1E-7 T 13-10-2018 MADE_000001022865 b48d53b40a30cbb910e9a3c892bf3938 244 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 11 68 1.2E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_000001022865 b48d53b40a30cbb910e9a3c892bf3938 244 SUPERFAMILY SSF47413 8 69 2.58E-8 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 SUPERFAMILY SSF50715 340 548 1.67E-72 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 SUPERFAMILY SSF52374 28 346 1.49E-95 T 13-10-2018 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Gene3D G3DSA:1.10.1160.10 261 339 5.1E-35 T 13-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 552 6.2E-268 T 13-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 5.8E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 5.8E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 5.8E-8 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 530 4.2E-58 T 13-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Gene3D G3DSA:3.40.50.620 28 247 1.1E-101 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Gene3D G3DSA:2.40.240.10 340 547 1.4E-76 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Gene3D G3DSA:2.40.240.10 348 466 1.4E-76 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Gene3D G3DSA:3.90.800.10 101 209 1.1E-101 T 13-10-2018 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 550 51.237 T 13-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 MADE_1009580 b9256b8538fd02fe6ba5dfa3a6ea7b71 555 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 6.1E-116 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MADE_1016070 511564e8062b1ecb485f1916b63f3304 353 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 353 2.6E-135 T 13-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 MADE_1016070 511564e8062b1ecb485f1916b63f3304 353 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 353 1.1E-68 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MADE_1014435 edfbefc3953632974214019cece86598 359 Gene3D G3DSA:3.30.70.1400 51 138 4.7E-89 T 13-10-2018 MADE_1014435 edfbefc3953632974214019cece86598 359 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 262 349 1.0E-20 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MADE_1014435 edfbefc3953632974214019cece86598 359 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 254 2.8E-89 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain MADE_1014435 edfbefc3953632974214019cece86598 359 Gene3D G3DSA:3.30.1360.120 7 231 4.7E-89 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MADE_1014435 edfbefc3953632974214019cece86598 359 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 354 45.043 T 13-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 MADE_1014435 edfbefc3953632974214019cece86598 359 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 354 1.5E-146 T 13-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MADE_1014435 edfbefc3953632974214019cece86598 359 SUPERFAMILY SSF103025 4 277 4.55E-93 T 13-10-2018 MADE_1014435 edfbefc3953632974214019cece86598 359 Gene3D G3DSA:4.10.1250.10 232 276 9.5E-28 T 13-10-2018 MADE_1014435 edfbefc3953632974214019cece86598 359 Gene3D G3DSA:2.40.30.110 277 359 1.3E-32 T 13-10-2018 MADE_1014435 edfbefc3953632974214019cece86598 359 SUPERFAMILY SSF101790 273 356 2.13E-25 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MADE_1014435 edfbefc3953632974214019cece86598 359 PIRSF PIRSF006487 1 358 7.7E-88 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MADE_1001725 fcf2685329ba29470617d022c4a53f7b 118 Pfam PF13473 Cupredoxin-like domain 13 117 1.7E-27 T 13-10-2018 IPR028096 EfeO-type cupredoxin-like domain MADE_1001725 fcf2685329ba29470617d022c4a53f7b 118 SUPERFAMILY SSF49503 13 117 8.75E-19 T 13-10-2018 IPR008972 Cupredoxin MADE_1001725 fcf2685329ba29470617d022c4a53f7b 118 Gene3D G3DSA:2.60.40.420 23 118 1.4E-23 T 13-10-2018 IPR008972 Cupredoxin MADE_1013080 2d0b2e1d87f36405031cc64f8bd853c8 541 Gene3D G3DSA:3.30.465.10 101 230 1.3E-34 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1013080 2d0b2e1d87f36405031cc64f8bd853c8 541 SUPERFAMILY SSF56176 14 229 4.16E-24 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_1013080 2d0b2e1d87f36405031cc64f8bd853c8 541 Gene3D G3DSA:3.40.462.10 246 499 6.1E-24 T 13-10-2018 IPR016170 Cytokinin dehydrogenase, C-terminal domain superfamily KEGG: 00908+1.5.99.12 MADE_1013080 2d0b2e1d87f36405031cc64f8bd853c8 541 SUPERFAMILY SSF55103 234 538 4.91E-17 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MADE_1013080 2d0b2e1d87f36405031cc64f8bd853c8 541 Pfam PF01565 FAD binding domain 38 181 7.3E-14 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MADE_1013080 2d0b2e1d87f36405031cc64f8bd853c8 541 Gene3D G3DSA:3.30.43.10 3 100 6.5E-11 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MADE_1005750 95d2fe4a46a324ee744823c47d50bf5f 680 SUPERFAMILY SSF64518 111 677 1.44E-28 T 13-10-2018 MADE_1005750 95d2fe4a46a324ee744823c47d50bf5f 680 Pfam PF00460 Flagella basal body rod protein 10 36 1.1E-6 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MADE_1005750 95d2fe4a46a324ee744823c47d50bf5f 680 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 6 329 5.0E-54 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MADE_1005750 95d2fe4a46a324ee744823c47d50bf5f 680 PRINTS PR01005 Flagellar hook-associated protein signature 13 36 4.3E-6 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MADE_1005750 95d2fe4a46a324ee744823c47d50bf5f 680 PRINTS PR01005 Flagellar hook-associated protein signature 149 173 4.3E-6 T 13-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 MADE_1005750 95d2fe4a46a324ee744823c47d50bf5f 680 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 627 677 1.9E-10 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MADE_1005750 95d2fe4a46a324ee744823c47d50bf5f 680 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site MADE_1014170 004ddd47cb995b12bbd65b097fe7d95a 182 PIRSF PIRSF011484 1 180 9.7E-70 T 13-10-2018 IPR009822 YaeQ MADE_1014170 004ddd47cb995b12bbd65b097fe7d95a 182 Gene3D G3DSA:3.10.640.10 1 180 3.8E-74 T 13-10-2018 IPR038590 YaeQ superfamily MADE_1014170 004ddd47cb995b12bbd65b097fe7d95a 182 Pfam PF07152 YaeQ protein 1 170 1.7E-73 T 13-10-2018 IPR009822 YaeQ MADE_1014170 004ddd47cb995b12bbd65b097fe7d95a 182 SMART SM01322 1 176 1.1E-111 T 13-10-2018 IPR009822 YaeQ MADE_1014170 004ddd47cb995b12bbd65b097fe7d95a 182 SUPERFAMILY SSF52980 2 176 4.56E-69 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MADE_1000615 19b0215319d0ffcc8ce471468b88aef8 722 Pfam PF03235 Protein of unknown function DUF262 40 337 1.4E-48 T 13-10-2018 IPR004919 Domain of unknown function DUF262 MADE_1000615 19b0215319d0ffcc8ce471468b88aef8 722 Pfam PF07510 Protein of unknown function (DUF1524) 572 663 1.0E-6 T 13-10-2018 IPR011089 Domain of unknown function DUF1524 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 49 7.2E-17 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 Pfam PF04552 Sigma-54, DNA binding domain 333 490 1.9E-71 T 13-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 490 1.8E-155 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 Pfam PF04963 Sigma-54 factor, core binding domain 127 319 1.0E-58 T 13-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 PRINTS PR00045 Sigma-54 factor signature 466 484 1.4E-29 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 PRINTS PR00045 Sigma-54 factor signature 392 404 1.4E-29 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 PRINTS PR00045 Sigma-54 factor signature 202 219 1.4E-29 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 PRINTS PR00045 Sigma-54 factor signature 408 419 1.4E-29 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 PIRSF PIRSF000774 1 493 2.6E-151 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 471 478 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 Gene3D G3DSA:1.10.10.60 433 490 5.6E-24 T 13-10-2018 MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 Gene3D G3DSA:1.10.10.1330 129 266 1.7E-22 T 13-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily MADE_1004185 81514bb4410ddcd97e9c5cd5c769443f 493 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 380 399 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 793 224.828 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 Gene3D G3DSA:1.10.1060.10 369 450 7.2E-12 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 Pfam PF13375 RnfC Barrel sandwich hybrid domain 19 120 2.9E-32 T 13-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 Gene3D G3DSA:3.40.50.11540 149 296 5.1E-11 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 SUPERFAMILY SSF142019 99 307 4.32E-62 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 Pfam PF10531 SLBB domain 300 350 2.1E-10 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 SUPERFAMILY SSF46548 340 451 5.36E-21 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 18 451 3.4E-182 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 422 433 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 Pfam PF13237 4Fe-4S dicluster domain 381 433 1.3E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain MADE_1006650 a7c3a84feea9aa9e06badbe16dcbad7e 852 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 145 287 9.2E-47 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SUPERFAMILY SSF50998 10 301 1.8E-51 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 Pfam PF00400 WD domain, G-beta repeat 141 173 7.7E-4 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 Pfam PF00400 WD domain, G-beta repeat 218 258 0.019 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 Gene3D G3DSA:2.130.10.10 3 140 6.3E-13 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SMART SM00320 134 173 7.3E-5 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SMART SM00320 7 46 4.3 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SMART SM00320 217 258 0.0011 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SMART SM00320 93 132 43.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SMART SM00320 269 307 44.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SMART SM00320 49 90 27.0 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 SMART SM00320 176 214 0.4 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 MADE_1019970 0dbef9983c4e01539c9a7dbfa186f205 310 Gene3D G3DSA:2.130.10.10 141 310 2.5E-33 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1008955 a8ec9c7caf515bdefe23777bb00e5313 518 SUPERFAMILY SSF55729 17 151 9.78E-15 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1008955 a8ec9c7caf515bdefe23777bb00e5313 518 SUPERFAMILY SSF56317 231 497 4.45E-60 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_1008955 a8ec9c7caf515bdefe23777bb00e5313 518 Gene3D G3DSA:3.60.110.10 229 513 8.3E-58 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_1008955 a8ec9c7caf515bdefe23777bb00e5313 518 Pfam PF00583 Acetyltransferase (GNAT) family 55 151 1.5E-6 T 13-10-2018 IPR000182 GNAT domain MADE_1008955 a8ec9c7caf515bdefe23777bb00e5313 518 Gene3D G3DSA:3.40.630.30 8 222 4.7E-52 T 13-10-2018 MADE_1008955 a8ec9c7caf515bdefe23777bb00e5313 518 Pfam PF00795 Carbon-nitrogen hydrolase 234 491 1.1E-35 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 Pfam PF00920 Dehydratase family 65 598 3.6E-157 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 601 0.0 T 13-10-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 Hamap MF_02094 Phosphogluconate dehydratase [edd]. 1 602 58.229 T 13-10-2018 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 Gene3D G3DSA:3.50.30.80 419 569 9.0E-50 T 13-10-2018 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 SUPERFAMILY SSF143975 1 418 3.79E-146 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 SUPERFAMILY SSF52016 419 603 2.98E-57 T 13-10-2018 MADE_1011695 098bd3bf56f7ee3703fee5e7ff83f656 608 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 505 516 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1011530 9b944b22231b17547fb9ef0969c89fb8 117 SUPERFAMILY SSF52821 14 103 9.04E-22 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1011530 9b944b22231b17547fb9ef0969c89fb8 117 Pfam PF00581 Rhodanese-like domain 21 106 1.3E-8 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1011530 9b944b22231b17547fb9ef0969c89fb8 117 Gene3D G3DSA:3.40.250.10 2 112 5.9E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1011530 9b944b22231b17547fb9ef0969c89fb8 117 SMART SM00450 19 116 3.1E-8 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 SUPERFAMILY SSF53335 141 379 3.05E-40 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Gene3D G3DSA:3.40.50.150 170 370 2.0E-119 T 13-10-2018 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 SMART SM00981 57 155 3.3E-15 T 13-10-2018 IPR004114 THUMP domain GO:0003723 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 SUPERFAMILY SSF53335 394 695 2.69E-72 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 475 655 9.1E-24 T 13-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Gene3D G3DSA:3.30.750.80 391 482 2.8E-34 T 13-10-2018 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 PIRSF PIRSF037618 1 699 4.9E-281 T 13-10-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Pfam PF02926 THUMP domain 37 154 6.7E-11 T 13-10-2018 IPR004114 THUMP domain GO:0003723 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Pfam PF01170 Putative RNA methylase family UPF0020 163 373 1.2E-45 T 13-10-2018 IPR000241 Putative RNA methylase domain MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 699 30.559 T 13-10-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 304 310 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Gene3D G3DSA:3.30.2130.30 6 255 2.0E-119 T 13-10-2018 MADE_1010175 9843f703b9daf26b5894e4339fc636b7 699 Gene3D G3DSA:3.40.50.150 483 699 7.1E-76 T 13-10-2018 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Gene3D G3DSA:1.10.287.130 169 244 3.3E-17 T 13-10-2018 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Gene3D G3DSA:3.30.565.10 245 401 1.1E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Gene3D G3DSA:3.40.50.2300 418 542 8.1E-31 T 13-10-2018 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SUPERFAMILY SSF52172 422 539 2.7E-30 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Pfam PF00072 Response regulator receiver domain 425 533 3.2E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SUPERFAMILY SSF55781 28 169 7.06E-26 T 13-10-2018 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SUPERFAMILY SSF55874 231 397 1.38E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Pfam PF00512 His Kinase A (phospho-acceptor) domain 174 242 2.6E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SMART SM00448 423 533 3.5E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Pfam PF01590 GAF domain 27 154 3.8E-8 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SMART SM00387 289 399 1.0E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Gene3D G3DSA:3.30.450.40 12 168 2.4E-17 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SMART SM00065 26 168 5.0E-8 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SUPERFAMILY SSF47384 158 244 1.26E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 397 3.3E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 340 2.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 354 2.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 377 2.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 396 2.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014900 f99fd97a74a825b3cf0d1f13865dfbbd 542 SMART SM00388 173 242 3.8E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_000001021685 1a8975115f1078bd746a4ad5609eae39 231 Gene3D G3DSA:3.30.70.1230 14 203 6.8E-24 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001021685 1a8975115f1078bd746a4ad5609eae39 231 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 19 196 4.2E-22 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MADE_000001021685 1a8975115f1078bd746a4ad5609eae39 231 SUPERFAMILY SSF55073 15 192 1.33E-25 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001021685 1a8975115f1078bd746a4ad5609eae39 231 SMART SM00044 2 211 5.3E-4 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 MADE_1009365 840a2ec3a33d876bc715912924b11f22 1195 PIRSF PIRSF005719 657 1195 5.9E-119 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein MADE_1009365 840a2ec3a33d876bc715912924b11f22 1195 PIRSF PIRSF005719 1 541 2.1E-127 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein MADE_1009365 840a2ec3a33d876bc715912924b11f22 1195 SUPERFAMILY SSF52540 2 1171 6.85E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009365 840a2ec3a33d876bc715912924b11f22 1195 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1179 1.0E-58 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MADE_1009365 840a2ec3a33d876bc715912924b11f22 1195 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1188 21.964 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 MADE_1009365 840a2ec3a33d876bc715912924b11f22 1195 Gene3D G3DSA:3.40.50.300 1 251 2.8E-54 T 13-10-2018 MADE_1009365 840a2ec3a33d876bc715912924b11f22 1195 Gene3D G3DSA:3.40.50.300 936 1195 3.1E-45 T 13-10-2018 MADE_1002360 331385b13c840d0aed97dd60ae042d76 729 SUPERFAMILY SSF55486 55 720 1.1E-170 T 13-10-2018 MADE_1002360 331385b13c840d0aed97dd60ae042d76 729 Gene3D G3DSA:1.10.1370.10 188 651 2.5E-206 T 13-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 MADE_1002360 331385b13c840d0aed97dd60ae042d76 729 Pfam PF01432 Peptidase family M3 270 719 1.9E-101 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 MADE_1002360 331385b13c840d0aed97dd60ae042d76 729 Gene3D G3DSA:1.10.1370.40 62 718 2.5E-206 T 13-10-2018 MADE_1002300 3a7778130649692c5dab83084e52cadc 63 SUPERFAMILY SSF46561 1 61 3.01E-22 T 13-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002300 3a7778130649692c5dab83084e52cadc 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 5.0E-22 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002300 3a7778130649692c5dab83084e52cadc 63 Pfam PF00831 Ribosomal L29 protein 5 60 6.2E-24 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002300 3a7778130649692c5dab83084e52cadc 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.642 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002300 3a7778130649692c5dab83084e52cadc 63 Gene3D G3DSA:1.10.287.310 1 63 5.7E-29 T 13-10-2018 MADE_1008075 6d84fdd9bc34fb38c9651effadcbde52 294 SUPERFAMILY SSF56112 4 288 8.6E-36 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1008075 6d84fdd9bc34fb38c9651effadcbde52 294 Gene3D G3DSA:3.30.200.20 1 97 2.0E-16 T 13-10-2018 MADE_1008075 6d84fdd9bc34fb38c9651effadcbde52 294 PIRSF PIRSF006221 1 294 2.8E-85 T 13-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MADE_1008075 6d84fdd9bc34fb38c9651effadcbde52 294 Gene3D G3DSA:3.90.1200.10 102 294 8.6E-58 T 13-10-2018 MADE_1008075 6d84fdd9bc34fb38c9651effadcbde52 294 Pfam PF03881 Fructosamine kinase 1 291 9.4E-93 T 13-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 SUPERFAMILY SSF53067 153 339 2.57E-49 T 13-10-2018 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 Gene3D G3DSA:3.90.640.10 190 263 9.8E-129 T 13-10-2018 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 SUPERFAMILY SSF53067 9 152 7.37E-38 T 13-10-2018 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 6.2E-166 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 Gene3D G3DSA:3.30.420.40 158 321 9.8E-129 T 13-10-2018 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 4.1E-65 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 4.1E-65 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 4.1E-65 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 4.1E-65 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 4.1E-65 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 Pfam PF06723 MreB/Mbl protein 11 337 2.2E-148 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 MADE_1001295 7d3296167bdce690d1bd6ca91c070ab7 347 Gene3D G3DSA:3.30.420.40 14 331 9.8E-129 T 13-10-2018 MADE_000001023310 65c1f8c069c38272c8f33476d31e5480 172 Gene3D G3DSA:3.30.70.1730 6 134 2.0E-27 T 13-10-2018 MADE_000001023310 65c1f8c069c38272c8f33476d31e5480 172 Pfam PF00466 Ribosomal protein L10 6 99 5.5E-23 T 13-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 MADE_000001023310 65c1f8c069c38272c8f33476d31e5480 172 SUPERFAMILY SSF160369 6 171 8.89E-46 T 13-10-2018 MADE_000001023310 65c1f8c069c38272c8f33476d31e5480 172 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 24.176 T 13-10-2018 IPR022973 Ribosomal protein L10 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 SUPERFAMILY SSF53738 214 320 1.77E-8 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 SUPERFAMILY SSF53738 26 240 5.89E-45 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 550 2.1E-262 T 13-10-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-6981|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7900|MetaCyc: PWY-7902 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Gene3D G3DSA:3.30.310.50 449 550 3.4E-33 T 13-10-2018 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Gene3D G3DSA:3.40.120.10 226 323 1.2E-41 T 13-10-2018 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Gene3D G3DSA:3.40.120.10 12 223 8.7E-72 T 13-10-2018 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 215 319 3.8E-16 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 184 2.8E-34 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Gene3D G3DSA:3.40.120.10 324 447 1.6E-30 T 13-10-2018 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 SUPERFAMILY SSF53738 310 453 1.06E-30 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 446 2.4E-26 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 145 154 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 497 543 3.5E-7 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1007745 cb0890cb39a7ab7b3bfda384c51987c0 550 SUPERFAMILY SSF55957 439 549 2.22E-18 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021875 29f2056f3fae9a61a12cce1b1acbaaf4 97 Gene3D G3DSA:3.30.110.60 1 97 4.3E-35 T 13-10-2018 IPR035920 YhbY-like superfamily MADE_000001021875 29f2056f3fae9a61a12cce1b1acbaaf4 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 96 2.3E-35 T 13-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 MADE_000001021875 29f2056f3fae9a61a12cce1b1acbaaf4 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 97 4.0E-35 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MADE_000001021875 29f2056f3fae9a61a12cce1b1acbaaf4 97 SMART SM01103 3 86 5.3E-43 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MADE_000001021875 29f2056f3fae9a61a12cce1b1acbaaf4 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 6.1E-22 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 MADE_000001021875 29f2056f3fae9a61a12cce1b1acbaaf4 97 SUPERFAMILY SSF75471 1 95 8.37E-31 T 13-10-2018 IPR035920 YhbY-like superfamily MADE_1012915 455eced86425a24e30623c3b6035e927 161 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 5.4E-66 T 13-10-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 MADE_1012915 455eced86425a24e30623c3b6035e927 161 SUPERFAMILY SSF46785 2 133 4.27E-36 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1012915 455eced86425a24e30623c3b6035e927 161 Gene3D G3DSA:1.10.10.10 1 144 1.6E-55 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1012915 455eced86425a24e30623c3b6035e927 161 Pfam PF02082 Transcriptional regulator 1 83 1.1E-27 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type MADE_1012915 455eced86425a24e30623c3b6035e927 161 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.9E-46 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Gene3D G3DSA:1.20.140.10 286 455 1.9E-43 T 13-10-2018 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Gene3D G3DSA:2.40.110.10 160 285 4.1E-29 T 13-10-2018 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 SUPERFAMILY SSF47203 286 465 4.35E-45 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 2.8E-5 T 13-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 449 2.1E-18 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 270 3.0E-17 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 SUPERFAMILY SSF56645 35 291 3.14E-53 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 157 3.0E-8 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Gene3D G3DSA:1.10.540.10 26 159 4.6E-12 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1008830 18026229b9f4aa479983fc386e78852d 586 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 481 578 1.0E-9 T 13-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MADE_1013330 6c5fac649ddadd8d65405fdb3c7e93e7 230 SUPERFAMILY SSF53474 7 228 1.31E-35 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1013330 6c5fac649ddadd8d65405fdb3c7e93e7 230 PRINTS PR00111 Alpha/beta hydrolase fold signature 11 26 2.1E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1013330 6c5fac649ddadd8d65405fdb3c7e93e7 230 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 81 2.1E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1013330 6c5fac649ddadd8d65405fdb3c7e93e7 230 PRINTS PR00111 Alpha/beta hydrolase fold signature 172 186 2.1E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1013330 6c5fac649ddadd8d65405fdb3c7e93e7 230 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 67 2.1E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1013330 6c5fac649ddadd8d65405fdb3c7e93e7 230 Pfam PF12697 Alpha/beta hydrolase family 12 220 4.9E-15 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1013330 6c5fac649ddadd8d65405fdb3c7e93e7 230 Gene3D G3DSA:3.40.50.1820 2 228 1.5E-50 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 SUPERFAMILY SSF56281 11 263 3.67E-70 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 Gene3D G3DSA:3.60.15.10 6 263 2.8E-91 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 10 263 44.62 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 176 263 8.3E-26 T 13-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 PIRSF PIRSF005457 6 263 5.7E-98 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 Pfam PF00753 Metallo-beta-lactamase superfamily 22 175 6.0E-13 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 12 263 1.0E-103 T 13-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 MADE_1010045 46e0f457113295e36ef93f20f9c6ff44 263 SMART SM00849 20 175 5.5E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 Gene3D G3DSA:3.20.20.450 723 986 6.6E-79 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 Pfam PF00990 Diguanylate cyclase, GGDEF domain 582 716 1.1E-30 T 13-10-2018 IPR000160 GGDEF domain MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 Gene3D G3DSA:3.30.450.20 405 516 1.6E-11 T 13-10-2018 MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 Pfam PF00563 EAL domain 739 979 2.2E-59 T 13-10-2018 IPR001633 EAL domain MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 SUPERFAMILY SSF141868 738 990 8.5E-69 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 SUPERFAMILY SSF55785 390 516 1.12E-13 T 13-10-2018 IPR035965 PAS domain superfamily MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 589 720 1.2E-32 T 13-10-2018 IPR000160 GGDEF domain MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 SMART SM00052 732 984 8.0E-64 T 13-10-2018 IPR001633 EAL domain MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 401 524 1.1E-10 T 13-10-2018 IPR000014 PAS domain MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 SUPERFAMILY SSF55073 581 722 6.43E-39 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 SMART SM00267 518 720 4.5E-43 T 13-10-2018 IPR000160 GGDEF domain MADE_000001022810 b935aa17f78e540f43267531fc2af586 995 Gene3D G3DSA:3.30.450.20 272 404 4.0E-6 T 13-10-2018 MADE_1007695 62c8c9bf745554db0555d298b3bf886f 365 Gene3D G3DSA:3.30.2300.20 82 180 7.5E-33 T 13-10-2018 MADE_1007695 62c8c9bf745554db0555d298b3bf886f 365 SUPERFAMILY SSF53335 190 287 3.71E-12 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1007695 62c8c9bf745554db0555d298b3bf886f 365 Pfam PF01728 FtsJ-like methyltransferase 191 251 4.3E-5 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 MADE_1007695 62c8c9bf745554db0555d298b3bf886f 365 Gene3D G3DSA:3.30.70.2810 4 81 6.4E-22 T 13-10-2018 MADE_1007695 62c8c9bf745554db0555d298b3bf886f 365 Gene3D G3DSA:3.40.50.150 181 361 2.0E-49 T 13-10-2018 MADE_1007695 62c8c9bf745554db0555d298b3bf886f 365 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 3 360 77.117 T 13-10-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 MADE_1007695 62c8c9bf745554db0555d298b3bf886f 365 PIRSF PIRSF028774 3 365 9.2E-130 T 13-10-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 Gene3D G3DSA:3.30.1330.60 175 290 5.1E-35 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 Gene3D G3DSA:2.60.40.2540 21 174 1.1E-47 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01021 OMPA domain signature 217 232 7.4E-5 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01021 OMPA domain signature 232 248 7.4E-5 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 SUPERFAMILY SSF103088 158 286 1.31E-29 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 Pfam PF00691 OmpA family 186 281 5.2E-20 T 13-10-2018 IPR006665 OmpA-like domain MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 173 200 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 270 290 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 103 120 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 122 144 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 147 166 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 27 43 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 65 83 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 84 102 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 203 229 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 232 249 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 250 269 1.8E-53 T 13-10-2018 MADE_1006600 d282c11ac7ced91f960d298b48da4459 290 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 44 62 1.8E-53 T 13-10-2018 MADE_1015960 b92a5f753dee7154c5d7a648bf790618 398 Pfam PF01566 Natural resistance-associated macrophage protein 20 371 2.5E-80 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 Gene3D G3DSA:3.40.50.10380 1 159 2.0E-67 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 SUPERFAMILY SSF51735 162 408 1.58E-81 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 SMART SM01274 17 150 5.4E-72 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 SMART SM00919 162 398 8.5E-139 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 SUPERFAMILY SSF53223 9 160 9.35E-52 T 13-10-2018 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 PIRSF PIRSF000106 41 411 1.6E-72 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 Gene3D G3DSA:3.40.50.720 160 411 8.8E-84 T 13-10-2018 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 Pfam PF00390 Malic enzyme, N-terminal domain 30 149 5.5E-26 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 Pfam PF03949 Malic enzyme, NAD binding domain 164 356 1.1E-25 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MADE_1018315 3eb5873e4c19d95cc45d496f4efe710c 411 ProSitePatterns PS00331 Malic enzymes signature. 158 174 - T 13-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Gene3D G3DSA:3.30.43.10 11 103 3.4E-122 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 SUPERFAMILY SSF55103 274 565 2.4E-108 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 PIRSF PIRSF000101 2 567 3.3E-270 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Pfam PF01565 FAD binding domain 45 164 4.3E-9 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Pfam PF09330 D-lactate dehydrogenase, membrane binding 276 565 1.1E-133 T 13-10-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 SUPERFAMILY SSF56176 8 271 7.01E-73 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Gene3D G3DSA:3.30.70.610 267 311 3.4E-122 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Gene3D G3DSA:3.30.43.10 518 565 1.5E-74 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Gene3D G3DSA:3.30.465.10 104 266 3.4E-122 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Hamap MF_02092 Quinone-dependent D-lactate dehydrogenase [dld]. 8 566 57.317 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Gene3D G3DSA:3.30.70.610 375 432 1.5E-74 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_1016380 f55b4129b35a0eb9d6c528ff45fe7e01 577 Gene3D G3DSA:3.30.1370.20 433 517 1.5E-74 T 13-10-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_1009370 31beb84c0561f132bc41333c71cc6dad 532 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 393 522 4.0E-56 T 13-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MADE_1009370 31beb84c0561f132bc41333c71cc6dad 532 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 392 518 4.3E-45 T 13-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MADE_1009370 31beb84c0561f132bc41333c71cc6dad 532 SUPERFAMILY SSF64383 391 526 9.29E-48 T 13-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 MADE_1009370 31beb84c0561f132bc41333c71cc6dad 532 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 285 520 6.6E-45 T 13-10-2018 IPR011919 Cell division protein ZipA GO:0016021|GO:0090529 MADE_1009370 31beb84c0561f132bc41333c71cc6dad 532 Hamap MF_00509 Cell division protein ZipA [zipA]. 3 522 23.251 T 13-10-2018 IPR011919 Cell division protein ZipA GO:0016021|GO:0090529 MADE_1009370 31beb84c0561f132bc41333c71cc6dad 532 SMART SM00771 390 520 7.8E-55 T 13-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 MADE_1009370 31beb84c0561f132bc41333c71cc6dad 532 Gene3D G3DSA:3.30.1400.10 388 528 1.3E-49 T 13-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 193 359 5.3E-24 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 154 1.2E-21 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 SUPERFAMILY SSF52540 4 184 5.49E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 SMART SM00382 192 339 0.23 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 SMART SM00382 1 177 1.0 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 Gene3D G3DSA:3.30.300.20 369 451 1.4E-20 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 Gene3D G3DSA:3.40.50.300 188 365 8.6E-49 T 13-10-2018 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 Pfam PF01926 50S ribosome-binding GTPase 5 119 1.6E-28 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 Pfam PF01926 50S ribosome-binding GTPase 196 313 2.4E-24 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 449 2.2E-179 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 369 449 2.2E-26 T 13-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 Hamap MF_00195 GTPase Der [der]. 2 452 39.024 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 Gene3D G3DSA:3.40.50.300 2 159 1.5E-42 T 13-10-2018 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 SUPERFAMILY SSF52540 138 455 2.56E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 PIRSF PIRSF006485 1 457 6.0E-180 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.2E-11 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 2.2E-11 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1005235 5c5ac2bcad6ff0395620f35caf192751 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 2.2E-11 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 SUPERFAMILY SSF53335 15 518 9.15E-101 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1020340 bc1859a5142722cd41a96f91303af364 713 Gene3D G3DSA:3.90.220.20 505 708 3.4E-22 T 13-10-2018 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 Gene3D G3DSA:1.20.1260.30 1 165 1.0E-64 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily MADE_1020340 bc1859a5142722cd41a96f91303af364 713 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 301 307 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 Gene3D G3DSA:3.40.50.150 166 494 4.9E-89 T 13-10-2018 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 SUPERFAMILY SSF116734 524 694 4.25E-20 T 13-10-2018 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 Pfam PF12161 HsdM N-terminal domain 19 159 9.1E-15 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MADE_1020340 bc1859a5142722cd41a96f91303af364 713 Pfam PF01420 Type I restriction modification DNA specificity domain 524 678 6.5E-6 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 Pfam PF02384 N-6 DNA Methylase 170 486 4.0E-64 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 216 230 4.3E-15 T 13-10-2018 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 298 310 4.3E-15 T 13-10-2018 MADE_1020340 bc1859a5142722cd41a96f91303af364 713 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 192 208 4.3E-15 T 13-10-2018 MADE_1009480 75805ea1d8b5d15232eb0171b8902eda 115 PIRSF PIRSF000169 1 115 2.9E-37 T 13-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MADE_1009480 75805ea1d8b5d15232eb0171b8902eda 115 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 10 113 9.8E-30 T 13-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 MADE_1009480 75805ea1d8b5d15232eb0171b8902eda 115 Gene3D G3DSA:1.20.1300.10 1 115 8.6E-26 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009480 75805ea1d8b5d15232eb0171b8902eda 115 SUPERFAMILY SSF81343 5 115 1.24E-25 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1006835 7912bf99eb7e6e3f6ca6f674c8bcc461 298 SUPERFAMILY SSF51735 2 294 1.23E-33 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1006835 7912bf99eb7e6e3f6ca6f674c8bcc461 298 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 292 8.2E-106 T 13-10-2018 IPR010099 Epimerase family protein SDR39U1 MADE_1006835 7912bf99eb7e6e3f6ca6f674c8bcc461 298 Pfam PF08338 Domain of unknown function (DUF1731) 249 295 2.3E-18 T 13-10-2018 IPR013549 Domain of unknown function DUF1731 MADE_1006835 7912bf99eb7e6e3f6ca6f674c8bcc461 298 Gene3D G3DSA:3.40.50.720 1 286 6.5E-70 T 13-10-2018 MADE_1006835 7912bf99eb7e6e3f6ca6f674c8bcc461 298 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 217 1.7E-13 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 SUPERFAMILY SSF52833 3 158 2.95E-61 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 Pfam PF00255 Glutathione peroxidase 4 110 4.7E-42 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 13-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 PIRSF PIRSF000303 2 162 9.8E-65 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 PRINTS PR01011 Glutathione peroxidase family signature 21 38 4.6E-21 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 PRINTS PR01011 Glutathione peroxidase family signature 56 72 4.6E-21 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 PRINTS PR01011 Glutathione peroxidase family signature 122 131 4.6E-21 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1009630 ece7de09fa8c59e79439f23e429cd158 163 Gene3D G3DSA:3.40.30.10 2 163 2.6E-70 T 13-10-2018 MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 Pfam PF05239 PRC-barrel domain 95 168 8.5E-12 T 13-10-2018 IPR027275 PRC-barrel domain MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 7 173 23.008 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 Gene3D G3DSA:2.40.30.60 1 91 3.9E-30 T 13-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 Pfam PF01782 RimM N-terminal domain 10 87 1.3E-24 T 13-10-2018 IPR002676 RimM, N-terminal GO:0006364 MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 Gene3D G3DSA:2.30.30.240 92 173 1.5E-26 T 13-10-2018 MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 8 173 1.2E-48 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 SUPERFAMILY SSF50447 6 91 1.48E-22 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_000001021055 23866c4047d07b1ced1516d5cbd88b70 173 SUPERFAMILY SSF50346 98 173 2.94E-19 T 13-10-2018 IPR011033 PRC-barrel-like superfamily MADE_1018380 542bcb5fee003865ff0a6f73e1636149 237 SMART SM00382 27 213 2.1E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1018380 542bcb5fee003865ff0a6f73e1636149 237 Gene3D G3DSA:3.40.50.300 1 234 1.0E-65 T 13-10-2018 MADE_1018380 542bcb5fee003865ff0a6f73e1636149 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1018380 542bcb5fee003865ff0a6f73e1636149 237 SUPERFAMILY SSF52540 1 227 7.42E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018380 542bcb5fee003865ff0a6f73e1636149 237 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.1E-88 T 13-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 MADE_1018380 542bcb5fee003865ff0a6f73e1636149 237 Pfam PF00005 ABC transporter 18 165 5.7E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1002775 e21b21f1255b030dee163f9e91111924 1028 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 172 2.9E-17 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1002775 e21b21f1255b030dee163f9e91111924 1028 Gene3D G3DSA:2.170.130.10 37 176 2.5E-28 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1002775 e21b21f1255b030dee163f9e91111924 1028 SUPERFAMILY SSF56935 31 1027 4.03E-76 T 13-10-2018 MADE_1002775 e21b21f1255b030dee163f9e91111924 1028 Pfam PF00593 TonB dependent receptor 546 1027 3.4E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1008565 eb0e876350476bcbdcc6fda823c211d6 239 Pfam PF00929 Exonuclease 4 167 2.2E-41 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1008565 eb0e876350476bcbdcc6fda823c211d6 239 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 215 3.1E-78 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1008565 eb0e876350476bcbdcc6fda823c211d6 239 Gene3D G3DSA:3.30.420.10 1 183 1.2E-58 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1008565 eb0e876350476bcbdcc6fda823c211d6 239 SUPERFAMILY SSF53098 1 177 8.68E-58 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1008565 eb0e876350476bcbdcc6fda823c211d6 239 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 232 8.8E-99 T 13-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1008565 eb0e876350476bcbdcc6fda823c211d6 239 SMART SM00479 2 176 2.3E-51 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1016650 64392632dd7d5eb408bb27d31dcf352f 194 SUPERFAMILY SSF103039 7 190 4.45E-37 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1016650 64392632dd7d5eb408bb27d31dcf352f 194 Gene3D G3DSA:3.40.1550.10 5 190 1.0E-38 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1016650 64392632dd7d5eb408bb27d31dcf352f 194 Pfam PF04509 CheC-like family 10 45 2.3E-9 T 13-10-2018 IPR007597 CheC-like protein GO:0016787 MADE_1016650 64392632dd7d5eb408bb27d31dcf352f 194 Pfam PF13690 Chemotaxis phosphatase CheX 69 157 2.6E-7 T 13-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain MADE_1013255 594121b24c0602f61169dee201315f43 640 SUPERFAMILY SSF110942 524 636 2.22E-34 T 13-10-2018 IPR037196 HSP90, C-terminal domain MADE_1013255 594121b24c0602f61169dee201315f43 640 Gene3D G3DSA:3.30.565.10 1 229 8.3E-78 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1013255 594121b24c0602f61169dee201315f43 640 Gene3D G3DSA:3.30.230.80 241 408 5.6E-72 T 13-10-2018 MADE_1013255 594121b24c0602f61169dee201315f43 640 Gene3D G3DSA:1.20.120.790 504 637 1.4E-43 T 13-10-2018 IPR037196 HSP90, C-terminal domain MADE_1013255 594121b24c0602f61169dee201315f43 640 Pfam PF00183 Hsp90 protein 223 637 5.0E-134 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MADE_1013255 594121b24c0602f61169dee201315f43 640 SUPERFAMILY SSF54211 242 497 7.43E-101 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1013255 594121b24c0602f61169dee201315f43 640 SUPERFAMILY SSF55874 8 218 1.83E-69 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1013255 594121b24c0602f61169dee201315f43 640 PRINTS PR00775 90kDa heat shock protein signature 175 192 3.0E-63 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MADE_1013255 594121b24c0602f61169dee201315f43 640 PRINTS PR00775 90kDa heat shock protein signature 8 28 3.0E-63 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MADE_1013255 594121b24c0602f61169dee201315f43 640 PRINTS PR00775 90kDa heat shock protein signature 78 95 3.0E-63 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MADE_1013255 594121b24c0602f61169dee201315f43 640 PRINTS PR00775 90kDa heat shock protein signature 123 145 3.0E-63 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MADE_1013255 594121b24c0602f61169dee201315f43 640 PRINTS PR00775 90kDa heat shock protein signature 96 113 3.0E-63 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MADE_1013255 594121b24c0602f61169dee201315f43 640 PRINTS PR00775 90kDa heat shock protein signature 29 51 3.0E-63 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MADE_1013255 594121b24c0602f61169dee201315f43 640 PRINTS PR00775 90kDa heat shock protein signature 193 211 3.0E-63 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal MADE_1013255 594121b24c0602f61169dee201315f43 640 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 636 32.809 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MADE_1013255 594121b24c0602f61169dee201315f43 640 Gene3D G3DSA:3.40.50.11260 409 498 8.2E-35 T 13-10-2018 MADE_1013255 594121b24c0602f61169dee201315f43 640 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 13-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 MADE_1013255 594121b24c0602f61169dee201315f43 640 SMART SM00387 30 187 1.2E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1013255 594121b24c0602f61169dee201315f43 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 186 3.6E-14 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1013255 594121b24c0602f61169dee201315f43 640 PIRSF PIRSF002583 2 640 2.3E-223 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 MADE_1016145 59917c919e9e0ba4c2e32dc35d1dce44 357 Pfam PF03747 ADP-ribosylglycohydrolase 12 334 1.6E-46 T 13-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 MADE_1016145 59917c919e9e0ba4c2e32dc35d1dce44 357 SUPERFAMILY SSF101478 6 348 1.11E-23 T 13-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily MADE_1016145 59917c919e9e0ba4c2e32dc35d1dce44 357 Gene3D G3DSA:1.10.4080.10 76 355 1.7E-18 T 13-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily MADE_1007760 dd973990e97de769ec0a124c46460051 347 PIRSF PIRSF017020 8 346 4.2E-134 T 13-10-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 MADE_1007760 dd973990e97de769ec0a124c46460051 347 Gene3D G3DSA:2.40.50.630 273 335 7.4E-114 T 13-10-2018 MADE_1007760 dd973990e97de769ec0a124c46460051 347 Gene3D G3DSA:3.40.630.10 34 272 7.4E-114 T 13-10-2018 MADE_1007760 dd973990e97de769ec0a124c46460051 347 TIGRFAM TIGR03242 arg_catab_astE: succinylglutamate desuccinylase 33 337 1.7E-103 T 13-10-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 MADE_1007760 dd973990e97de769ec0a124c46460051 347 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 58 340 3.8E-61 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MADE_1007760 dd973990e97de769ec0a124c46460051 347 Hamap MF_00767 Succinylglutamate desuccinylase [astE]. 1 347 147.445 T 13-10-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 MADE_1007760 dd973990e97de769ec0a124c46460051 347 SUPERFAMILY SSF53187 18 340 5.03E-77 T 13-10-2018 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 10 864 0.0 T 13-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 SUPERFAMILY SSF63737 4 192 6.93E-43 T 13-10-2018 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Gene3D G3DSA:1.10.390.10 279 442 2.3E-64 T 13-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 550 865 1.9E-101 T 13-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 324 4.4E-9 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 126 141 4.4E-9 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 4.4E-9 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 257 267 4.4E-9 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 293 308 4.4E-9 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Gene3D G3DSA:1.10.1740.60 194 278 7.6E-38 T 13-10-2018 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 443 545 1.4E-16 T 13-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Gene3D G3DSA:2.60.40.1840 443 545 2.3E-15 T 13-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Pfam PF01433 Peptidase family M1 domain 207 437 9.6E-62 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 SUPERFAMILY SSF55486 204 450 7.51E-75 T 13-10-2018 MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Gene3D G3DSA:1.25.50.10 549 865 2.6E-100 T 13-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily MADE_1010150 f95ee68289a5d41cb53a14ccfa659432 869 Gene3D G3DSA:2.60.40.1730 13 193 3.8E-68 T 13-10-2018 MADE_1006745 a6095f0489a18b47bddd1b14592a4624 501 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 5 496 1.8E-207 T 13-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MADE_1006745 a6095f0489a18b47bddd1b14592a4624 501 Gene3D G3DSA:1.20.1730.10 5 495 1.8E-91 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_1006745 a6095f0489a18b47bddd1b14592a4624 501 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 156 181 - T 13-10-2018 IPR018212 Sodium/solute symporter, conserved site MADE_1006745 a6095f0489a18b47bddd1b14592a4624 501 Pfam PF00474 Sodium:solute symporter family 34 437 6.6E-101 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_1006745 a6095f0489a18b47bddd1b14592a4624 501 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 437 3.4E-90 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 335 1.4E-12 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Gene3D G3DSA:3.40.50.300 550 764 3.0E-90 T 13-10-2018 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 SUPERFAMILY SSF81923 4 156 3.79E-42 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 SMART SM00382 198 343 7.0E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 SMART SM00382 597 736 1.3E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 SUPERFAMILY SSF52540 546 853 3.65E-84 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 SMART SM01086 766 855 4.5E-35 T 13-10-2018 IPR019489 Clp ATPase, C-terminal MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 1.5E-11 T 13-10-2018 IPR004176 Clp, N-terminal MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 3.0E-13 T 13-10-2018 IPR004176 Clp, N-terminal MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 846 1.7E-24 T 13-10-2018 IPR019489 Clp ATPase, C-terminal MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Gene3D G3DSA:3.40.50.300 348 544 1.3E-65 T 13-10-2018 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.6E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 1.6E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 1.6E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 1.6E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 853 0.0 T 13-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 760 2.0E-56 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Gene3D G3DSA:3.40.50.300 158 347 1.7E-74 T 13-10-2018 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Gene3D G3DSA:1.10.8.60 766 857 6.1E-27 T 13-10-2018 MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 SUPERFAMILY SSF52540 159 545 2.31E-98 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022275 4f4fbd1ecd8b5f621011130c5d9ac34a 858 Gene3D G3DSA:1.10.1780.10 1 148 2.2E-31 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 MADE_1001695 a0e6ccebacc79f4fc58794999b238d62 248 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 24 234 1.2E-77 T 13-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 MADE_1001695 a0e6ccebacc79f4fc58794999b238d62 248 SUPERFAMILY SSF52540 36 235 2.45E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1001695 a0e6ccebacc79f4fc58794999b238d62 248 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 52 214 4.0E-28 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MADE_1001695 a0e6ccebacc79f4fc58794999b238d62 248 PIRSF PIRSF005624 17 247 1.8E-84 T 13-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MADE_1001695 a0e6ccebacc79f4fc58794999b238d62 248 Gene3D G3DSA:3.40.50.300 32 243 4.4E-57 T 13-10-2018 MADE_1008260 58360a9bdf4fed19ef991e6292e7be7d 376 SUPERFAMILY SSF53756 3 372 3.04E-44 T 13-10-2018 MADE_1008260 58360a9bdf4fed19ef991e6292e7be7d 376 Gene3D G3DSA:3.40.50.2000 173 358 5.6E-36 T 13-10-2018 MADE_1008260 58360a9bdf4fed19ef991e6292e7be7d 376 Pfam PF00534 Glycosyl transferases group 1 192 338 9.0E-23 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1008260 58360a9bdf4fed19ef991e6292e7be7d 376 Gene3D G3DSA:3.40.50.2000 14 367 5.6E-36 T 13-10-2018 MADE_1015430 de6b7d4cf27b36d86f9a53e9187ccad3 117 SMART SM00360 2 75 3.8E-25 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 MADE_1015430 de6b7d4cf27b36d86f9a53e9187ccad3 117 Gene3D G3DSA:3.30.70.330 1 97 2.0E-27 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MADE_1015430 de6b7d4cf27b36d86f9a53e9187ccad3 117 SUPERFAMILY SSF54928 2 81 4.03E-27 T 13-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 MADE_1015430 de6b7d4cf27b36d86f9a53e9187ccad3 117 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 3 73 5.9E-22 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 MADE_1013550 3542a5523318830f49da31659c174aef 84 SUPERFAMILY SSF143120 1 81 1.12E-23 T 13-10-2018 IPR036165 YefM-like superfamily MADE_1013550 3542a5523318830f49da31659c174aef 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 55 6.7E-7 T 13-10-2018 MADE_1013550 3542a5523318830f49da31659c174aef 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 73 2.1E-22 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MADE_1013550 3542a5523318830f49da31659c174aef 84 Gene3D G3DSA:3.40.1620.10 1 40 4.4E-8 T 13-10-2018 MADE_1013550 3542a5523318830f49da31659c174aef 84 Gene3D G3DSA:1.10.1220.170 41 84 3.6E-14 T 13-10-2018 MADE_000001020715 c424370bab28083f922d276fb39512d0 300 SUPERFAMILY SSF53649 32 288 2.83E-22 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MADE_000001020715 c424370bab28083f922d276fb39512d0 300 Gene3D G3DSA:3.40.720.10 4 300 2.5E-85 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MADE_000001020715 c424370bab28083f922d276fb39512d0 300 Pfam PF00884 Sulfatase 5 282 6.1E-48 T 13-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MADE_1009820 505fcf34d1d41425d665bfc71f8cb799 80 ProSitePatterns PS00018 EF-hand calcium-binding domain. 21 33 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site MADE_1009820 505fcf34d1d41425d665bfc71f8cb799 80 SMART SM00054 48 76 0.0061 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_1009820 505fcf34d1d41425d665bfc71f8cb799 80 SMART SM00054 12 40 4.4E-5 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_1009820 505fcf34d1d41425d665bfc71f8cb799 80 Gene3D G3DSA:1.10.238.10 1 78 1.4E-18 T 13-10-2018 MADE_1009820 505fcf34d1d41425d665bfc71f8cb799 80 Pfam PF13499 EF-hand domain pair 11 73 5.8E-12 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_1009820 505fcf34d1d41425d665bfc71f8cb799 80 ProSitePatterns PS00018 EF-hand calcium-binding domain. 57 69 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site MADE_1009820 505fcf34d1d41425d665bfc71f8cb799 80 SUPERFAMILY SSF47473 4 74 4.38E-19 T 13-10-2018 IPR011992 EF-hand domain pair MADE_1012015 f04d2a13e03a4a95b76bd1e61d4bf489 345 Pfam PF01548 Transposase 7 145 4.5E-12 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1012015 f04d2a13e03a4a95b76bd1e61d4bf489 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 290 5.4E-13 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_000001021640 f04d2a13e03a4a95b76bd1e61d4bf489 345 Pfam PF01548 Transposase 7 145 4.5E-12 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_000001021640 f04d2a13e03a4a95b76bd1e61d4bf489 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 290 5.4E-13 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1001885 172f8b712a1d76e077a051c65d7d2c98 117 SUPERFAMILY SSF81296 27 117 7.0E-17 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1001885 172f8b712a1d76e077a051c65d7d2c98 117 Gene3D G3DSA:2.60.40.1220 22 117 1.0E-14 T 13-10-2018 MADE_1001885 172f8b712a1d76e077a051c65d7d2c98 117 Pfam PF04234 CopC domain 27 116 1.4E-14 T 13-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 Gene3D G3DSA:1.10.3210.10 312 503 6.9E-49 T 13-10-2018 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 PIRSF PIRSF001267 6 503 6.9E-170 T 13-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 Hamap MF_01550 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [gppA]. 10 503 52.967 T 13-10-2018 IPR023709 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase GO:0008894|GO:0015974 KEGG: 00230+3.6.1.40 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 SUPERFAMILY SSF53067 140 310 9.18E-43 T 13-10-2018 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 Pfam PF02541 Ppx/GppA phosphatase family 29 310 4.0E-79 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 SUPERFAMILY SSF109604 315 501 3.01E-43 T 13-10-2018 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 Gene3D G3DSA:3.30.420.40 17 305 2.3E-79 T 13-10-2018 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 Gene3D G3DSA:3.30.420.150 120 297 2.3E-79 T 13-10-2018 MADE_1002845 ba08b074288d1a6d748957eebc84175c 503 SUPERFAMILY SSF53067 15 134 6.05E-35 T 13-10-2018 MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 Pfam PF00294 pfkB family carbohydrate kinase 6 285 8.1E-46 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 Hamap MF_01987 Ribokinase [rbsK]. 1 292 20.769 T 13-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 PRINTS PR00990 Ribokinase signature 32 51 1.8E-27 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 PRINTS PR00990 Ribokinase signature 168 183 1.8E-27 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 PRINTS PR00990 Ribokinase signature 101 114 1.8E-27 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 PRINTS PR00990 Ribokinase signature 5 26 1.8E-27 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 PRINTS PR00990 Ribokinase signature 208 219 1.8E-27 T 13-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 Gene3D G3DSA:3.40.1190.20 1 298 1.4E-81 T 13-10-2018 IPR029056 Ribokinase-like MADE_1014890 b7666d70768b8dd08950602cd9d4d474 298 SUPERFAMILY SSF53613 1 293 7.48E-68 T 13-10-2018 IPR029056 Ribokinase-like MADE_1009710 4882c741831815ddeade1c45f19184be 357 SMART SM00387 254 354 1.9E-4 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1009710 4882c741831815ddeade1c45f19184be 357 Gene3D G3DSA:3.30.565.10 215 353 2.2E-19 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1009710 4882c741831815ddeade1c45f19184be 357 Pfam PF06580 Histidine kinase 160 239 3.5E-25 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 MADE_1009710 4882c741831815ddeade1c45f19184be 357 SUPERFAMILY SSF55874 215 351 2.88E-17 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 Pfam PF00520 Ion transport protein 27 254 6.9E-34 T 13-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 SUPERFAMILY SSF81324 21 249 8.11E-53 T 13-10-2018 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 PRINTS PR00169 Potassium channel signature 194 216 1.4E-36 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 PRINTS PR00169 Potassium channel signature 20 48 1.4E-36 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 PRINTS PR00169 Potassium channel signature 134 160 1.4E-36 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 PRINTS PR00169 Potassium channel signature 223 249 1.4E-36 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 PRINTS PR00169 Potassium channel signature 163 186 1.4E-36 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 PRINTS PR00169 Potassium channel signature 62 85 1.4E-36 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 MADE_1019765 842a7b840f78b886faac0f492e6efaf0 311 Gene3D G3DSA:1.10.287.70 26 253 1.4E-60 T 13-10-2018 MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 660 2.8E-304 T 13-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 SUPERFAMILY SSF52518 335 526 5.58E-65 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 Pfam PF02780 Transketolase, C-terminal domain 541 656 1.1E-15 T 13-10-2018 IPR033248 Transketolase, C-terminal domain MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 2.0E-42 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 SMART SM00861 355 526 2.8E-63 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 SUPERFAMILY SSF52518 5 330 1.18E-119 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 Gene3D G3DSA:3.40.50.970 327 538 1.6E-79 T 13-10-2018 MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 Gene3D G3DSA:3.40.50.970 3 326 3.5E-131 T 13-10-2018 MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 SUPERFAMILY SSF52922 534 663 6.28E-45 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 6.8E-165 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1004345 3bab417a5160a104c732945aa6fb9f44 663 Gene3D G3DSA:3.40.50.920 539 662 4.0E-43 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1015375 104c1475d83c3a78fa602772f04f4ebc 111 SUPERFAMILY SSF54593 5 110 1.75E-17 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1015375 104c1475d83c3a78fa602772f04f4ebc 111 Gene3D G3DSA:3.10.180.10 6 110 9.3E-11 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1015895 dd4d5c8df2c43aa20be9976c3c375e48 114 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 114 36.155 T 13-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 MADE_1015895 dd4d5c8df2c43aa20be9976c3c375e48 114 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 95 112 - T 13-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 MADE_1015895 dd4d5c8df2c43aa20be9976c3c375e48 114 Pfam PF01521 Iron-sulphur cluster biosynthesis 9 109 1.3E-20 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MADE_1015895 dd4d5c8df2c43aa20be9976c3c375e48 114 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 114 2.0E-38 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MADE_1015895 dd4d5c8df2c43aa20be9976c3c375e48 114 Gene3D G3DSA:2.60.300.12 8 114 2.3E-33 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MADE_1015895 dd4d5c8df2c43aa20be9976c3c375e48 114 SUPERFAMILY SSF89360 6 100 6.41E-31 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MADE_1010070 aaa9c15880d23e8fde454cb44e866429 197 SUPERFAMILY SSF51283 1 191 1.67E-59 T 13-10-2018 IPR036157 dUTPase-like superfamily MADE_1010070 aaa9c15880d23e8fde454cb44e866429 197 Gene3D G3DSA:2.70.40.10 1 162 8.5E-53 T 13-10-2018 IPR036157 dUTPase-like superfamily MADE_1010070 aaa9c15880d23e8fde454cb44e866429 197 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 190 2.4E-68 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MADE_1010070 aaa9c15880d23e8fde454cb44e866429 197 Pfam PF00692 dUTPase 75 185 7.8E-10 T 13-10-2018 IPR029054 dUTPase-like MADE_1010070 aaa9c15880d23e8fde454cb44e866429 197 Hamap MF_00146 dCTP deaminase [dcd]. 1 190 34.24 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 MADE_1012500 54417baf669cda2a9978afc716e8da9d 280 Gene3D G3DSA:3.20.20.140 1 276 3.9E-66 T 13-10-2018 MADE_1012500 54417baf669cda2a9978afc716e8da9d 280 PIRSF PIRSF005902 1 278 3.3E-58 T 13-10-2018 IPR001130 TatD family GO:0016788 MADE_1012500 54417baf669cda2a9978afc716e8da9d 280 SUPERFAMILY SSF51556 1 275 1.71E-63 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1012500 54417baf669cda2a9978afc716e8da9d 280 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 1 9 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MADE_1012500 54417baf669cda2a9978afc716e8da9d 280 Pfam PF01026 TatD related DNase 2 273 1.0E-56 T 13-10-2018 IPR001130 TatD family GO:0016788 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 2.8E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 2.8E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 2.8E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 SMART SM00448 6 120 5.7E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 SUPERFAMILY SSF46894 133 205 2.75E-16 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 SUPERFAMILY SSF52172 7 132 7.12E-28 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 Gene3D G3DSA:3.40.50.12740 7 205 5.4E-50 T 13-10-2018 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 SMART SM00421 142 199 8.8E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 Pfam PF00072 Response regulator receiver domain 8 120 4.4E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015670 8c42f9511dd76dda327f958a1af07526 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 199 1.8E-16 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 SUPERFAMILY SSF50939 321 414 4.41E-6 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 Pfam PF15902 Sortilin, neurotensin receptor 3, 135 260 1.4E-9 T 13-10-2018 IPR031778 Sortilin, N-terminal MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 SUPERFAMILY SSF110296 99 332 5.49E-58 T 13-10-2018 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 Gene3D G3DSA:2.130.10.10 206 265 3.8E-9 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 Gene3D G3DSA:2.130.10.10 54 205 2.9E-27 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 Gene3D G3DSA:2.130.10.10 436 606 4.9E-9 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 SUPERFAMILY SSF110296 51 122 2.14E-10 T 13-10-2018 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 Gene3D G3DSA:2.130.10.10 266 435 5.5E-21 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 Gene3D G3DSA:2.130.10.10 607 710 7.3E-21 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1016305 4debf9541c4e80e2a0d5668996208334 941 SUPERFAMILY SSF50939 442 747 6.47E-48 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 MADE_1010295 5758f48000343a3ab47ea6a389179346 435 SUPERFAMILY SSF111369 140 352 7.19E-18 T 13-10-2018 MADE_1010295 5758f48000343a3ab47ea6a389179346 435 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 127 348 1.6E-34 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1010295 5758f48000343a3ab47ea6a389179346 435 Gene3D G3DSA:2.40.30.170 128 355 1.0E-51 T 13-10-2018 MADE_1010295 5758f48000343a3ab47ea6a389179346 435 Gene3D G3DSA:2.40.50.100 142 277 1.0E-51 T 13-10-2018 MADE_1010295 5758f48000343a3ab47ea6a389179346 435 Gene3D G3DSA:2.40.420.20 116 414 1.0E-51 T 13-10-2018 MADE_1010295 5758f48000343a3ab47ea6a389179346 435 Gene3D G3DSA:1.10.287.470 176 242 1.0E-51 T 13-10-2018 MADE_1010295 5758f48000343a3ab47ea6a389179346 435 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 119 422 5.5E-32 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1013910 d1b7f6962999930df3ed30f9e676f2e2 760 SUPERFAMILY SSF53448 483 737 1.5E-46 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013910 d1b7f6962999930df3ed30f9e676f2e2 760 Pfam PF00535 Glycosyl transferase family 2 490 670 3.0E-20 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1013910 d1b7f6962999930df3ed30f9e676f2e2 760 Pfam PF00535 Glycosyl transferase family 2 231 388 7.9E-24 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1013910 d1b7f6962999930df3ed30f9e676f2e2 760 SUPERFAMILY SSF53448 229 441 1.03E-46 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013910 d1b7f6962999930df3ed30f9e676f2e2 760 Gene3D G3DSA:3.90.550.10 473 722 6.4E-47 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013910 d1b7f6962999930df3ed30f9e676f2e2 760 Gene3D G3DSA:3.90.550.10 180 472 8.7E-62 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1003815 f397f25995d75976e2938e258de13e78 123 Pfam PF01230 HIT domain 12 107 3.5E-27 T 13-10-2018 IPR001310 Histidine triad (HIT) protein MADE_1003815 f397f25995d75976e2938e258de13e78 123 Gene3D G3DSA:3.30.428.10 1 114 7.0E-38 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1003815 f397f25995d75976e2938e258de13e78 123 PRINTS PR00332 Histidine triad family signature 5 21 9.8E-21 T 13-10-2018 IPR001310 Histidine triad (HIT) protein MADE_1003815 f397f25995d75976e2938e258de13e78 123 PRINTS PR00332 Histidine triad family signature 26 44 9.8E-21 T 13-10-2018 IPR001310 Histidine triad (HIT) protein MADE_1003815 f397f25995d75976e2938e258de13e78 123 PRINTS PR00332 Histidine triad family signature 94 104 9.8E-21 T 13-10-2018 IPR001310 Histidine triad (HIT) protein MADE_1003815 f397f25995d75976e2938e258de13e78 123 ProSitePatterns PS00892 HIT domain signature. 87 105 - T 13-10-2018 IPR019808 Histidine triad, conserved site MADE_1003815 f397f25995d75976e2938e258de13e78 123 SUPERFAMILY SSF54197 2 113 2.47E-37 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1018180 2ea6a27563fecb0b329579033471941e 557 Pfam PF00672 HAMP domain 178 229 8.0E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 SMART SM00387 434 545 3.8E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018180 2ea6a27563fecb0b329579033471941e 557 SUPERFAMILY SSF55874 385 548 3.25E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018180 2ea6a27563fecb0b329579033471941e 557 Gene3D G3DSA:1.10.287.130 266 389 4.5E-25 T 13-10-2018 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 Gene3D G3DSA:3.30.565.10 395 549 5.5E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018180 2ea6a27563fecb0b329579033471941e 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 438 544 3.2E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018180 2ea6a27563fecb0b329579033471941e 557 Gene3D G3DSA:1.20.1480.50 140 240 1.2E-5 T 13-10-2018 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 488 1.2E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 542 1.2E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 523 1.2E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 502 1.2E-18 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 Pfam PF00512 His Kinase A (phospho-acceptor) domain 290 393 1.3E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 SMART SM00388 289 394 0.0058 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 SUPERFAMILY SSF47384 284 394 2.75E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1018180 2ea6a27563fecb0b329579033471941e 557 SMART SM00304 176 233 4.1E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1004150 76ab3a5bab17fcbe1ade4aa681118930 210 SUPERFAMILY SSF52833 7 90 4.07E-22 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1004150 76ab3a5bab17fcbe1ade4aa681118930 210 Gene3D G3DSA:3.40.30.10 11 200 9.7E-80 T 13-10-2018 MADE_1004150 76ab3a5bab17fcbe1ade4aa681118930 210 SUPERFAMILY SSF47616 82 205 7.67E-26 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1004150 76ab3a5bab17fcbe1ade4aa681118930 210 Gene3D G3DSA:1.20.1050.10 89 192 9.7E-80 T 13-10-2018 MADE_1004150 76ab3a5bab17fcbe1ade4aa681118930 210 Pfam PF00043 Glutathione S-transferase, C-terminal domain 101 192 2.7E-11 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal MADE_1004150 76ab3a5bab17fcbe1ade4aa681118930 210 Pfam PF13417 Glutathione S-transferase, N-terminal domain 13 87 7.7E-15 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 36 131 5.7E-10 T 13-10-2018 IPR000014 PAS domain MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 263 1.9E-15 T 13-10-2018 IPR000014 PAS domain MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 Pfam PF08447 PAS fold 47 127 2.4E-7 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 Pfam PF08447 PAS fold 166 252 4.5E-13 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 SMART SM00086 217 259 7.1E-4 T 13-10-2018 IPR001610 PAC motif MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 276 433 7.5E-38 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 SMART SM00283 248 435 1.5E-16 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 SMART SM00091 142 212 0.26 T 13-10-2018 IPR000014 PAS domain MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 SMART SM00091 20 90 5.7 T 13-10-2018 IPR000014 PAS domain MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 SUPERFAMILY SSF58104 248 435 2.49E-50 T 13-10-2018 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 SUPERFAMILY SSF55785 154 253 4.01E-22 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 Gene3D G3DSA:3.30.450.20 7 128 3.0E-14 T 13-10-2018 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 SUPERFAMILY SSF55785 35 128 9.42E-14 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 Gene3D G3DSA:3.30.450.20 129 249 1.3E-20 T 13-10-2018 MADE_1003720 f5fe30409f8952cf224c2dfde5e39cf8 438 Gene3D G3DSA:1.10.287.950 250 438 5.0E-47 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 53 577 8.9E-125 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 Gene3D G3DSA:1.10.246.130 284 404 4.5E-34 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 Pfam PF01019 Gamma-glutamyltranspeptidase 67 580 1.4E-148 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 Gene3D G3DSA:3.60.20.40 405 585 9.8E-60 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 SUPERFAMILY SSF56235 44 584 3.28E-162 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 423 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 427 445 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 488 505 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 166 185 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 463 478 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 268 284 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 74 99 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 148 166 2.2E-67 T 13-10-2018 MADE_1011090 71b1ff2e50e1793e774778c51f82cc63 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 298 317 2.2E-67 T 13-10-2018 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SUPERFAMILY SSF51197 560 600 7.0E-5 T 13-10-2018 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Pfam PF13432 Tetratricopeptide repeat 53 106 1.1E-5 T 13-10-2018 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Pfam PF13432 Tetratricopeptide repeat 111 172 0.0015 T 13-10-2018 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Pfam PF13374 Tetratricopeptide repeat 177 206 0.0013 T 13-10-2018 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Pfam PF13759 Putative 2OG-Fe(II) oxygenase 503 595 8.4E-21 T 13-10-2018 IPR012668 Conserved hypothetical protein CHP02466 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Gene3D G3DSA:1.25.40.10 273 411 1.2E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SUPERFAMILY SSF48452 45 303 4.93E-32 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Pfam PF13181 Tetratricopeptide repeat 347 378 0.0069 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Gene3D G3DSA:2.60.120.620 417 602 3.9E-21 T 13-10-2018 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SMART SM00028 175 208 0.0044 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SMART SM00028 141 174 16.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SMART SM00028 209 242 0.35 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SMART SM00028 107 140 52.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SMART SM00028 73 106 14.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SMART SM00028 345 378 34.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SMART SM00028 39 72 210.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 Gene3D G3DSA:1.25.40.10 12 272 1.2E-41 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006240 a6561aa58a052b13b428c0c015bde3c1 604 SUPERFAMILY SSF48452 282 412 2.91E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1012485 f447e573db8b22aec84886cc62ff4777 841 Pfam PF07238 PilZ domain 155 212 1.8E-5 T 13-10-2018 IPR009875 PilZ domain GO:0035438 MADE_1013685 1badb410a34058225627d983561cda52 819 Pfam PF07452 CHRD domain 585 696 3.8E-23 T 13-10-2018 IPR010895 CHRD MADE_1013685 1badb410a34058225627d983561cda52 819 Pfam PF07452 CHRD domain 710 814 2.1E-24 T 13-10-2018 IPR010895 CHRD MADE_1013685 1badb410a34058225627d983561cda52 819 Pfam PF07452 CHRD domain 467 576 8.2E-29 T 13-10-2018 IPR010895 CHRD MADE_1013685 1badb410a34058225627d983561cda52 819 Pfam PF14344 Domain of unknown function (DUF4397) 251 367 8.0E-22 T 13-10-2018 IPR025510 Domain of unknown function DUF4397 MADE_1013685 1badb410a34058225627d983561cda52 819 Pfam PF14344 Domain of unknown function (DUF4397) 36 156 1.1E-21 T 13-10-2018 IPR025510 Domain of unknown function DUF4397 MADE_1013685 1badb410a34058225627d983561cda52 819 SMART SM00754 464 578 4.6E-23 T 13-10-2018 IPR010895 CHRD MADE_1013685 1badb410a34058225627d983561cda52 819 SMART SM00754 584 698 1.8E-18 T 13-10-2018 IPR010895 CHRD MADE_1013685 1badb410a34058225627d983561cda52 819 SMART SM00754 702 816 1.9E-31 T 13-10-2018 IPR010895 CHRD MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 Gene3D G3DSA:3.40.50.720 2 198 1.1E-54 T 13-10-2018 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 14 169 1.2E-49 T 13-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 PIRSF PIRSF000114 7 343 2.2E-101 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 67 94 9.6E-41 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 184 208 9.6E-41 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 249 266 9.6E-41 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 17 34 9.6E-41 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 143 163 9.6E-41 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 209 233 9.6E-41 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 Gene3D G3DSA:1.10.1040.10 200 343 3.0E-52 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 SUPERFAMILY SSF48179 190 342 4.42E-57 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 199 220 - T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 13 333 38.033 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 SUPERFAMILY SSF51735 15 189 4.15E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1002705 1a149bf4d48b6497b8b0084d7ca9381c 343 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 191 330 2.5E-52 T 13-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 Gene3D G3DSA:3.20.20.450 372 628 3.4E-90 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 Gene3D G3DSA:3.30.70.270 193 371 2.3E-52 T 13-10-2018 MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 SUPERFAMILY SSF55073 204 361 4.32E-43 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 SMART SM00052 370 616 2.4E-96 T 13-10-2018 IPR001633 EAL domain MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 SMART SM00267 188 360 1.5E-55 T 13-10-2018 IPR000160 GGDEF domain MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 195 359 5.9E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 Pfam PF00563 EAL domain 376 611 3.1E-66 T 13-10-2018 IPR001633 EAL domain MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 SUPERFAMILY SSF141868 376 623 1.57E-81 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1011830 a5a4ae22b2674d901c9a87f47a2180af 630 Pfam PF00990 Diguanylate cyclase, GGDEF domain 199 356 2.5E-44 T 13-10-2018 IPR000160 GGDEF domain MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 SUPERFAMILY SSF53244 333 470 3.66E-41 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 Pfam PF02875 Mur ligase family, glutamate ligase domain 333 405 1.2E-5 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 Gene3D G3DSA:3.40.50.720 4 100 9.7E-15 T 13-10-2018 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 SUPERFAMILY SSF53623 120 329 1.19E-47 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 8 470 31.933 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 Gene3D G3DSA:3.40.1190.10 101 331 6.3E-56 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 Gene3D G3DSA:3.90.190.20 332 467 1.0E-40 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 Pfam PF08245 Mur ligase middle domain 125 311 3.2E-28 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 SUPERFAMILY SSF51984 5 101 4.58E-12 T 13-10-2018 MADE_1015160 1ca8acae49cb19c1b7434fa6418d27d9 479 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 468 8.2E-119 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MADE_1012595 085bf4838549016032de89fe18b2e658 130 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 36 2.9E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012595 085bf4838549016032de89fe18b2e658 130 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 36 4.7E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012595 085bf4838549016032de89fe18b2e658 130 Gene3D G3DSA:3.30.700.10 17 129 1.3E-7 T 13-10-2018 MADE_1012595 085bf4838549016032de89fe18b2e658 130 SUPERFAMILY SSF54523 17 114 2.51E-10 T 13-10-2018 MADE_1010995 6308c4e2a7794bf36d1bc078de038d5b 282 Pfam PF13365 Trypsin-like peptidase domain 27 204 4.3E-9 T 13-10-2018 MADE_1010995 6308c4e2a7794bf36d1bc078de038d5b 282 SUPERFAMILY SSF50494 7 232 3.9E-14 T 13-10-2018 IPR009003 Peptidase S1, PA clan MADE_1010995 6308c4e2a7794bf36d1bc078de038d5b 282 Gene3D G3DSA:2.40.10.120 1 208 2.2E-8 T 13-10-2018 MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 SMART SM00924 31 134 1.9E-18 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 Pfam PF01769 Divalent cation transporter 316 437 1.4E-25 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 SUPERFAMILY SSF161093 273 444 6.02E-49 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 Gene3D G3DSA:1.10.357.20 271 444 5.3E-48 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 Gene3D G3DSA:1.25.60.10 7 129 8.2E-8 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 SUPERFAMILY SSF158791 20 130 3.4E-16 T 13-10-2018 MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 Pfam PF03448 MgtE intracellular N domain 34 131 2.0E-17 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 Gene3D G3DSA:3.10.580.10 130 255 5.9E-36 T 13-10-2018 MADE_1000970 202037c2fe0ee977685cea22ebf1675e 445 SUPERFAMILY SSF54631 134 270 4.42E-13 T 13-10-2018 MADE_1006480 96b5d793eeee03648d7aa3d580922f0d 279 Gene3D G3DSA:3.30.2350.10 1 236 6.9E-46 T 13-10-2018 MADE_1006480 96b5d793eeee03648d7aa3d580922f0d 279 Pfam PF00849 RNA pseudouridylate synthase 12 192 9.9E-24 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1006480 96b5d793eeee03648d7aa3d580922f0d 279 SUPERFAMILY SSF55120 4 235 2.73E-43 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1018275 4c695d166ecad06e37760e9962867671 109 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 9 106 5.3E-35 T 13-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 MADE_1018275 4c695d166ecad06e37760e9962867671 109 SUPERFAMILY SSF89447 9 48 5.23E-5 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily MADE_1018275 4c695d166ecad06e37760e9962867671 109 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 6 98 3.0E-21 T 13-10-2018 MADE_1015155 9d3c8022ee0af9d1216be18500793c5c 470 Pfam PF01098 Cell cycle protein 30 382 1.0E-110 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015155 9d3c8022ee0af9d1216be18500793c5c 470 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 341 365 - T 13-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015155 9d3c8022ee0af9d1216be18500793c5c 470 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 25 392 41.775 T 13-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015155 9d3c8022ee0af9d1216be18500793c5c 470 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 28 382 2.9E-128 T 13-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1004945 b96991b2f85c8c653694e698fbb02f50 149 Pfam PF00258 Flavodoxin 6 136 2.5E-24 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MADE_1004945 b96991b2f85c8c653694e698fbb02f50 149 Gene3D G3DSA:3.40.50.360 1 148 1.2E-40 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1004945 b96991b2f85c8c653694e698fbb02f50 149 PRINTS PR00369 Flavodoxin signature 5 18 8.5E-5 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1004945 b96991b2f85c8c653694e698fbb02f50 149 PRINTS PR00369 Flavodoxin signature 82 92 8.5E-5 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1004945 b96991b2f85c8c653694e698fbb02f50 149 PRINTS PR00369 Flavodoxin signature 107 126 8.5E-5 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1004945 b96991b2f85c8c653694e698fbb02f50 149 PRINTS PR00369 Flavodoxin signature 51 62 8.5E-5 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1004945 b96991b2f85c8c653694e698fbb02f50 149 SUPERFAMILY SSF52218 1 147 6.01E-36 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1010665 cb9f50c81f13e7d4a9b6a75f7a1c56ee 122 Pfam PF02635 DsrE/DsrF-like family 3 122 6.6E-16 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein MADE_1010665 cb9f50c81f13e7d4a9b6a75f7a1c56ee 122 SUPERFAMILY SSF75169 1 122 1.53E-27 T 13-10-2018 IPR027396 DsrEFH-like MADE_1010665 cb9f50c81f13e7d4a9b6a75f7a1c56ee 122 Gene3D G3DSA:3.40.1260.10 1 122 8.1E-34 T 13-10-2018 IPR027396 DsrEFH-like MADE_1012440 039f1853b89797d12261621f15e3298c 366 PIRSF PIRSF001259 1 365 1.1E-127 T 13-10-2018 MADE_1012440 039f1853b89797d12261621f15e3298c 366 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 39.299 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012440 039f1853b89797d12261621f15e3298c 366 Gene3D G3DSA:3.90.870.10 1 206 1.0E-90 T 13-10-2018 MADE_1012440 039f1853b89797d12261621f15e3298c 366 Pfam PF00925 GTP cyclohydrolase II 208 364 3.0E-34 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MADE_1012440 039f1853b89797d12261621f15e3298c 366 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 199 1.3E-78 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012440 039f1853b89797d12261621f15e3298c 366 SUPERFAMILY SSF55821 2 201 2.52E-88 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MADE_1012440 039f1853b89797d12261621f15e3298c 366 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 7.7E-87 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012440 039f1853b89797d12261621f15e3298c 366 SUPERFAMILY SSF142695 205 365 4.58E-44 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MADE_1003635 e1f4ac09a550098faca5e1cea8be94df 781 Gene3D G3DSA:2.170.130.10 33 153 9.6E-8 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1003635 e1f4ac09a550098faca5e1cea8be94df 781 SUPERFAMILY SSF56935 35 781 5.8E-72 T 13-10-2018 MADE_1003635 e1f4ac09a550098faca5e1cea8be94df 781 Pfam PF00593 TonB dependent receptor 298 779 4.2E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1003635 e1f4ac09a550098faca5e1cea8be94df 781 ProSitePatterns PS00018 EF-hand calcium-binding domain. 298 310 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site MADE_1003635 e1f4ac09a550098faca5e1cea8be94df 781 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 153 1.4E-4 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 SMART SM00862 145 220 6.2E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 Pfam PF00072 Response regulator receiver domain 3 113 3.8E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 Gene3D G3DSA:3.40.50.2300 1 121 3.9E-36 T 13-10-2018 MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 SUPERFAMILY SSF52172 1 118 1.29E-35 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 8.0E-102 T 13-10-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 SUPERFAMILY SSF46894 118 221 6.8E-29 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 Gene3D G3DSA:1.10.10.10 122 227 5.9E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 SMART SM00448 1 112 9.2E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1001535 be0edd0353a1ea05284deb06f119e9ed 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 1.4E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1007150 62176a7bb47edc08e2130dadbd8dc374 373 Gene3D G3DSA:3.40.50.300 114 320 7.4E-75 T 13-10-2018 MADE_1007150 62176a7bb47edc08e2130dadbd8dc374 373 Pfam PF02562 PhoH-like protein 117 320 1.1E-95 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 MADE_1007150 62176a7bb47edc08e2130dadbd8dc374 373 SUPERFAMILY SSF52540 116 292 5.45E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 158 7.0E-32 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 SUPERFAMILY SSF53155 3 83 2.55E-16 T 13-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 157 3.8E-36 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 Gene3D G3DSA:3.30.160.70 1 74 3.3E-13 T 13-10-2018 MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 158 39.47 T 13-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 Gene3D G3DSA:1.10.10.10 77 161 6.5E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 74 7.0E-5 T 13-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 MADE_1019485 79c3f17613b1e78a879587c0fa9a6c79 164 SUPERFAMILY SSF46767 77 158 5.76E-31 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Pfam PF13291 ACT domain 620 697 4.7E-16 T 13-10-2018 IPR002912 ACT domain MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 SMART SM00471 41 153 3.1E-9 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 696 3.7E-253 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Pfam PF13328 HD domain 26 175 3.8E-53 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 SMART SM00954 235 345 1.8E-61 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 SUPERFAMILY SSF81271 375 448 1.59E-19 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Gene3D G3DSA:3.10.20.30 381 456 2.7E-29 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 SUPERFAMILY SSF109604 4 190 1.29E-73 T 13-10-2018 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Gene3D G3DSA:1.10.3210.10 3 190 3.0E-80 T 13-10-2018 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Pfam PF04607 Region found in RelA / SpoT proteins 235 344 3.2E-35 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Gene3D G3DSA:3.30.70.260 621 703 4.7E-14 T 13-10-2018 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Pfam PF02824 TGS domain 388 447 7.6E-19 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 SUPERFAMILY SSF55021 623 699 7.5E-9 T 13-10-2018 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 Gene3D G3DSA:3.30.460.10 193 325 1.3E-45 T 13-10-2018 MADE_1000770 2205e50756c45f1f4f13f7c304cca0ba 703 SUPERFAMILY SSF81301 181 392 4.25E-60 T 13-10-2018 MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 Pfam PF00128 Alpha amylase, catalytic domain 177 279 2.2E-14 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 Pfam PF00128 Alpha amylase, catalytic domain 294 491 3.8E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 54 125 2.4E-17 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 SUPERFAMILY SSF51445 138 523 3.43E-92 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 SUPERFAMILY SSF81296 52 142 6.12E-22 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 PIRSF PIRSF000463 37 597 6.6E-87 T 13-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 Gene3D G3DSA:3.20.20.80 153 522 2.5E-106 T 13-10-2018 MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 SMART SM00642 163 521 5.9E-14 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1016165 f5791bd800b3e2f75f16422f9ee37aa2 623 Gene3D G3DSA:2.60.40.10 39 140 2.2E-25 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1006560 21c193b7cf5568d1627ba347eccc5668 116 Pfam PF00462 Glutaredoxin 22 86 1.5E-17 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MADE_1006560 21c193b7cf5568d1627ba347eccc5668 116 PIRSF PIRSF005894 3 113 1.1E-50 T 13-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 MADE_1006560 21c193b7cf5568d1627ba347eccc5668 116 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 10 106 9.2E-46 T 13-10-2018 IPR004480 Monothiol glutaredoxin-related MADE_1006560 21c193b7cf5568d1627ba347eccc5668 116 SUPERFAMILY SSF52833 8 107 7.23E-34 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1006560 21c193b7cf5568d1627ba347eccc5668 116 Gene3D G3DSA:3.40.30.10 7 113 8.6E-31 T 13-10-2018 MADE_1010265 b14d341bcf202bc9c0daa44ba7dd3cc0 439 SUPERFAMILY SSF56954 17 425 7.59E-55 T 13-10-2018 MADE_1010265 b14d341bcf202bc9c0daa44ba7dd3cc0 439 Gene3D G3DSA:1.20.1600.10 27 426 1.8E-41 T 13-10-2018 MADE_1010265 b14d341bcf202bc9c0daa44ba7dd3cc0 439 Pfam PF02321 Outer membrane efflux protein 253 423 8.0E-9 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1010265 b14d341bcf202bc9c0daa44ba7dd3cc0 439 Pfam PF02321 Outer membrane efflux protein 43 220 8.1E-12 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 636 36.618 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 Gene3D G3DSA:1.20.1270.10 524 607 6.8E-28 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 Gene3D G3DSA:3.30.420.40 5 379 1.6E-167 T 13-10-2018 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 Gene3D G3DSA:3.30.420.40 180 366 1.6E-167 T 13-10-2018 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 SUPERFAMILY SSF53067 4 184 4.07E-66 T 13-10-2018 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 Gene3D G3DSA:2.60.34.10 383 523 6.6E-65 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 4.9E-289 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 Pfam PF00012 Hsp70 protein 4 602 9.9E-264 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 SUPERFAMILY SSF100934 534 606 1.37E-6 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 SUPERFAMILY SSF100920 384 540 5.23E-61 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 Gene3D G3DSA:3.90.640.10 229 316 1.6E-167 T 13-10-2018 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 198 208 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 365 385 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 469 485 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 138 158 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 334 350 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 PRINTS PR00301 70kDa heat shock protein signature 388 407 1.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 SUPERFAMILY SSF53067 187 382 2.86E-67 T 13-10-2018 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MADE_1007055 79b5071af9205358b993b2cd4ffe82f5 642 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.1E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 1 179 2.5E-60 T 13-10-2018 IPR017757 Transcriptional repressor BetI MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 74 180 1.1E-20 T 13-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 186 79.25 T 13-10-2018 IPR017757 Transcriptional repressor BetI MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 Gene3D G3DSA:1.10.357.10 2 185 1.5E-32 T 13-10-2018 MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 SUPERFAMILY SSF48498 71 160 9.93E-10 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 SUPERFAMILY SSF46689 4 63 3.49E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.3E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1006080 24ab3d4b0f9200974fbd6837ea326fd4 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.3E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 286 867 2.1E-270 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Gene3D G3DSA:3.40.50.300 366 539 1.1E-71 T 13-10-2018 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Gene3D G3DSA:3.30.56.50 2 50 8.1E-20 T 13-10-2018 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 SUPERFAMILY SSF46955 3 49 3.11E-10 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 ProSitePatterns PS01176 Initiation factor 2 signature. 819 841 - T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Pfam PF11987 Translation-initiation factor 2 653 758 3.5E-36 T 13-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 59 93 2.0E-10 T 13-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 SUPERFAMILY SSF52156 646 775 2.75E-37 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 371 526 4.2E-34 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Gene3D G3DSA:2.40.30.10 540 658 1.4E-39 T 13-10-2018 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Pfam PF00009 Elongation factor Tu GTP binding domain 372 529 1.2E-35 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 SUPERFAMILY SSF50447 541 623 1.17E-22 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 866 17.272 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 SUPERFAMILY SSF50447 770 866 3.33E-33 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 294 344 2.2E-15 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 1.8E-6 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Gene3D G3DSA:3.40.50.10050 663 769 1.1E-36 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 Gene3D G3DSA:2.40.30.10 770 867 3.4E-34 T 13-10-2018 MADE_1008920 5b4165a557b511da9e0fd805668cb5de 868 SUPERFAMILY SSF52540 366 532 5.22E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004395 3281b45714572bdda8ae3f8bca70bf25 519 SUPERFAMILY SSF161098 247 504 7.19E-36 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1004395 3281b45714572bdda8ae3f8bca70bf25 519 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 289 514 2.2E-17 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1004395 3281b45714572bdda8ae3f8bca70bf25 519 Gene3D G3DSA:1.10.3720.10 262 516 3.6E-31 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1004395 3281b45714572bdda8ae3f8bca70bf25 519 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 254 513 1.5E-72 T 13-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 MADE_1020205 7f880fbfe5d87ebc18f167c54ed3f9bd 821 SUPERFAMILY SSF55486 372 600 4.71E-40 T 13-10-2018 MADE_1020205 7f880fbfe5d87ebc18f167c54ed3f9bd 821 Pfam PF01433 Peptidase family M1 domain 373 594 4.2E-13 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1020205 7f880fbfe5d87ebc18f167c54ed3f9bd 821 Gene3D G3DSA:1.10.390.60 371 598 9.0E-28 T 13-10-2018 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 19 180 2.4E-34 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 TIGRFAM TIGR00436 era: GTP-binding protein Era 21 291 2.6E-104 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 Pfam PF01926 50S ribosome-binding GTPase 22 136 1.1E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 Gene3D G3DSA:3.30.300.20 197 313 1.7E-43 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 Hamap MF_00367 GTPase Era [era]. 17 308 36.172 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 22 42 3.8E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 71 86 3.8E-6 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 SUPERFAMILY SSF52540 22 217 1.97E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 Pfam PF07650 KH domain 220 296 1.1E-20 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 SUPERFAMILY SSF54814 193 308 1.39E-43 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MADE_1012510 26acc3ff324d3ab7fdd014bae3c07b8c 314 Gene3D G3DSA:3.40.50.300 15 195 2.4E-50 T 13-10-2018 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 SUPERFAMILY SSF56024 320 499 4.71E-51 T 13-10-2018 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 7 681 3.6E-249 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Hamap MF_00347 Polyphosphate kinase [ppk]. 4 685 26.393 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 PIRSF PIRSF015589 1 689 4.9E-236 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Gene3D G3DSA:3.30.870.10 504 690 5.6E-74 T 13-10-2018 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 SUPERFAMILY SSF56024 504 686 6.73E-69 T 13-10-2018 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 SUPERFAMILY SSF143724 110 316 5.69E-56 T 13-10-2018 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Gene3D G3DSA:3.30.1840.10 113 311 5.5E-61 T 13-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Gene3D G3DSA:1.20.58.310 9 112 1.0E-32 T 13-10-2018 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Pfam PF13090 Polyphosphate kinase C-terminal domain 334 680 6.7E-141 T 13-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Gene3D G3DSA:3.30.870.10 323 503 6.5E-67 T 13-10-2018 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Pfam PF02503 Polyphosphate kinase middle domain 122 322 4.0E-38 T 13-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 Pfam PF13089 Polyphosphate kinase N-terminal domain 7 112 1.0E-31 T 13-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 MADE_1004380 2bf389d3f5242c7393cebffafbcf77b5 690 SUPERFAMILY SSF140356 6 109 1.7E-29 T 13-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 MADE_1007680 30926eda7f956553cec66948e198cd19 300 Gene3D G3DSA:3.40.190.10 163 261 3.8E-60 T 13-10-2018 MADE_1007680 30926eda7f956553cec66948e198cd19 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1007680 30926eda7f956553cec66948e198cd19 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1007680 30926eda7f956553cec66948e198cd19 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1007680 30926eda7f956553cec66948e198cd19 300 SUPERFAMILY SSF46785 2 85 9.09E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1007680 30926eda7f956553cec66948e198cd19 300 SUPERFAMILY SSF53850 91 295 3.8E-34 T 13-10-2018 MADE_1007680 30926eda7f956553cec66948e198cd19 300 Gene3D G3DSA:3.40.190.10 103 288 3.8E-60 T 13-10-2018 MADE_1007680 30926eda7f956553cec66948e198cd19 300 Gene3D G3DSA:1.10.10.10 7 95 2.2E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1007680 30926eda7f956553cec66948e198cd19 300 Pfam PF03466 LysR substrate binding domain 91 290 8.7E-35 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1007680 30926eda7f956553cec66948e198cd19 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.3E-19 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 SUPERFAMILY SSF51344 3 86 1.1E-25 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 SUPERFAMILY SSF46604 88 137 3.4E-14 T 13-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 132 1.4E-9 T 13-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 21.42 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 132 1.7E-46 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 Gene3D G3DSA:2.60.15.10 3 90 7.2E-33 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 84 1.3E-30 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 Gene3D G3DSA:1.20.5.440 91 133 8.5E-15 T 13-10-2018 MADE_1020445 abb15b184b8188f935dd54e2e486ac63 137 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 86 2.0E-31 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 SUPERFAMILY SSF51735 464 637 8.54E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 SUPERFAMILY SSF53633 1 298 2.79E-70 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Gene3D G3DSA:3.30.2130.10 304 464 2.0E-48 T 13-10-2018 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Gene3D G3DSA:3.30.360.10 626 796 3.6E-118 T 13-10-2018 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Gene3D G3DSA:3.40.1160.10 3 295 4.0E-80 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 460 1.0E-122 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 607 2.1E-24 T 13-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 SUPERFAMILY SSF55021 383 475 8.01E-23 T 13-10-2018 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Pfam PF00742 Homoserine dehydrogenase 615 811 7.2E-49 T 13-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Gene3D G3DSA:1.20.120.1320 41 142 4.0E-80 T 13-10-2018 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Pfam PF00696 Amino acid kinase family 2 284 6.7E-42 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 661 683 - T 13-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Gene3D G3DSA:3.40.50.720 466 812 3.6E-118 T 13-10-2018 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 PIRSF PIRSF000727 1 818 0.0 T 13-10-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+1.1.1.3+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+1.1.1.3+2.7.2.4|KEGG: 00300+1.1.1.3+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 SUPERFAMILY SSF55347 615 798 2.03E-50 T 13-10-2018 MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 Pfam PF01842 ACT domain 324 380 6.3E-8 T 13-10-2018 IPR002912 ACT domain MADE_1015480 438f2214ab59ff33e322c297d809b0f4 821 SUPERFAMILY SSF55021 306 381 7.63E-21 T 13-10-2018 MADE_1012645 58c044549ef679610725c4155ca8df63 314 Gene3D G3DSA:3.40.50.11270 12 96 4.8E-111 T 13-10-2018 MADE_1012645 58c044549ef679610725c4155ca8df63 314 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 284 5.3E-99 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MADE_1012645 58c044549ef679610725c4155ca8df63 314 Gene3D G3DSA:3.40.1010.20 97 196 4.8E-111 T 13-10-2018 MADE_1012645 58c044549ef679610725c4155ca8df63 314 Gene3D G3DSA:3.40.1010.20 6 282 4.8E-111 T 13-10-2018 MADE_1012645 58c044549ef679610725c4155ca8df63 314 Pfam PF02401 LytB protein 3 283 5.2E-92 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MADE_1012645 58c044549ef679610725c4155ca8df63 314 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 286 37.146 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 331 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 10 350 1.6E-74 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 Pfam PF00083 Sugar (and other) transporter 412 518 1.4E-25 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 Pfam PF00083 Sugar (and other) transporter 12 345 1.3E-76 T 13-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 PRINTS PR00171 Sugar transporter signature 19 29 9.6E-16 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 PRINTS PR00171 Sugar transporter signature 271 281 9.6E-16 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 PRINTS PR00171 Sugar transporter signature 419 440 9.6E-16 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 PRINTS PR00171 Sugar transporter signature 442 454 9.6E-16 T 13-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 SUPERFAMILY SSF103473 10 516 8.89E-69 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1019050 7ed8f0849735dece64bb5968823a3fd5 524 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 82 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 SUPERFAMILY SSF51905 16 375 7.87E-52 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PIRSF PIRSF000350 2 479 3.2E-234 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 Gene3D G3DSA:3.50.50.60 20 337 1.1E-103 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 52 62 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PRINTS PR00945 Mercuric reductase class II signature 190 207 4.7E-69 T 13-10-2018 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PRINTS PR00945 Mercuric reductase class II signature 28 46 4.7E-69 T 13-10-2018 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PRINTS PR00945 Mercuric reductase class II signature 452 471 4.7E-69 T 13-10-2018 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PRINTS PR00945 Mercuric reductase class II signature 64 83 4.7E-69 T 13-10-2018 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PRINTS PR00945 Mercuric reductase class II signature 155 172 4.7E-69 T 13-10-2018 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PRINTS PR00945 Mercuric reductase class II signature 210 225 4.7E-69 T 13-10-2018 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 PRINTS PR00945 Mercuric reductase class II signature 387 407 4.7E-69 T 13-10-2018 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 355 461 1.2E-28 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 Gene3D G3DSA:3.50.50.60 163 279 1.1E-103 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 SUPERFAMILY SSF55424 354 476 1.03E-32 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 Gene3D G3DSA:3.30.390.30 354 479 1.7E-42 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 TIGRFAM TIGR02053 MerA: mercury(II) reductase 18 479 2.6E-162 T 13-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 MADE_1005505 1ff9ee4986d6cf2cd45112b38b24eff1 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 336 9.4E-59 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1004860 df714f7e52e65685f0d9ffc810598620 292 Gene3D G3DSA:3.90.550.10 5 205 1.4E-18 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1004860 df714f7e52e65685f0d9ffc810598620 292 SUPERFAMILY SSF53448 5 230 6.43E-26 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1004860 df714f7e52e65685f0d9ffc810598620 292 Pfam PF00535 Glycosyl transferase family 2 17 160 1.4E-9 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1009515 21d1e549dd6d1e4d3635609be28d93e7 938 SUPERFAMILY SSF56935 25 938 1.94E-75 T 13-10-2018 MADE_1009515 21d1e549dd6d1e4d3635609be28d93e7 938 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 162 1.3E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1009515 21d1e549dd6d1e4d3635609be28d93e7 938 Gene3D G3DSA:2.170.130.10 45 166 2.4E-14 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1009515 21d1e549dd6d1e4d3635609be28d93e7 938 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 40 938 2.3E-157 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_1009515 21d1e549dd6d1e4d3635609be28d93e7 938 Pfam PF14905 Outer membrane protein beta-barrel family 558 732 6.6E-7 T 13-10-2018 MADE_1009355 8b14c4eb84d62c9ba5ca5310c263f902 529 Gene3D G3DSA:1.25.40.10 56 263 7.9E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1009355 8b14c4eb84d62c9ba5ca5310c263f902 529 SUPERFAMILY SSF81901 106 248 7.94E-8 T 13-10-2018 MADE_000001022690 bf8983f66bb3e0686f1c4fc5664ab312 320 SUPERFAMILY SSF51126 48 302 6.65E-23 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor MADE_000001022690 bf8983f66bb3e0686f1c4fc5664ab312 320 Gene3D G3DSA:2.160.20.10 47 316 5.7E-11 T 13-10-2018 IPR012334 Pectin lyase fold MADE_1012635 fd28cd32e38d58b0e056284d717ebdfd 286 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012635 fd28cd32e38d58b0e056284d717ebdfd 286 Pfam PF16074 Type IV Pilus-assembly protein W 156 277 7.5E-18 T 13-10-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 MADE_1012635 fd28cd32e38d58b0e056284d717ebdfd 286 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 31 1.4E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012635 fd28cd32e38d58b0e056284d717ebdfd 286 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 8.4E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 PIRSF PIRSF000410 1 279 5.4E-78 T 13-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 PRINTS PR00996 Glutamate methyltransferase family signature 147 163 8.0E-39 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 PRINTS PR00996 Glutamate methyltransferase family signature 33 46 8.0E-39 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 PRINTS PR00996 Glutamate methyltransferase family signature 72 84 8.0E-39 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 PRINTS PR00996 Glutamate methyltransferase family signature 235 258 8.0E-39 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 PRINTS PR00996 Glutamate methyltransferase family signature 112 132 8.0E-39 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 PRINTS PR00996 Glutamate methyltransferase family signature 216 230 8.0E-39 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 Gene3D G3DSA:1.10.155.10 3 77 7.5E-19 T 13-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 Pfam PF03705 CheR methyltransferase, all-alpha domain 12 61 4.9E-14 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 SMART SM00138 11 276 4.2E-78 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 SUPERFAMILY SSF53335 79 267 2.34E-48 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 Pfam PF01739 CheR methyltransferase, SAM binding domain 79 269 8.3E-56 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 Gene3D G3DSA:3.40.50.150 78 278 4.5E-59 T 13-10-2018 MADE_1015080 5150d740a1f84ecfaf42e1fef871b041 284 SUPERFAMILY SSF47757 8 78 1.44E-18 T 13-10-2018 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1043 1254 6.0E-7 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Gene3D G3DSA:1.10.3170.10 177 381 2.2E-100 T 13-10-2018 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Gene3D G3DSA:1.10.486.10 641 783 3.0E-104 T 13-10-2018 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Pfam PF13361 UvrD-like helicase C-terminal domain 497 689 9.7E-7 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 SUPERFAMILY SSF52980 958 1279 4.02E-70 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Gene3D G3DSA:3.40.50.300 31 489 2.2E-100 T 13-10-2018 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 32 1278 8.4E-238 T 13-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 SUPERFAMILY SSF52540 26 882 2.0E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Pfam PF13361 UvrD-like helicase C-terminal domain 737 878 5.8E-10 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 29 1279 19.784 T 13-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Pfam PF00580 UvrD/REP helicase N-terminal domain 36 489 1.3E-54 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 MADE_1013630 1a6c822db711f5c379d643b2fb7797e0 1336 Gene3D G3DSA:3.40.50.300 498 889 3.0E-104 T 13-10-2018 MADE_1016190 aff10e863eced086cce770df18785506 356 SUPERFAMILY SSF46626 213 356 5.06E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1016190 aff10e863eced086cce770df18785506 356 Pfam PF03150 Di-haem cytochrome c peroxidase 62 205 8.5E-38 T 13-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 MADE_1016190 aff10e863eced086cce770df18785506 356 Gene3D G3DSA:1.10.760.10 213 356 3.3E-26 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1016190 aff10e863eced086cce770df18785506 356 PIRSF PIRSF000294 10 356 1.1E-62 T 13-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 MADE_1016190 aff10e863eced086cce770df18785506 356 SUPERFAMILY SSF46626 46 194 2.07E-40 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1016190 aff10e863eced086cce770df18785506 356 Gene3D G3DSA:1.10.760.10 47 212 8.5E-46 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 665 684 1.0E-27 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 688 700 1.0E-27 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 314 328 1.0E-27 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 612 622 1.0E-27 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 601 1.0E-27 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 466 480 1.0E-27 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 197 774 2.6E-188 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 237 744 9.4E-92 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 SUPERFAMILY SSF81665 213 747 1.7E-10 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 Gene3D G3DSA:3.40.50.1000 447 717 1.5E-93 T 13-10-2018 IPR023214 HAD superfamily MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 Pfam PF00122 E1-E2 ATPase 265 445 5.1E-56 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 SUPERFAMILY SSF81653 268 364 4.71E-28 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 468 474 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00943 Copper-transporting ATPase signature 182 201 4.5E-10 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00943 Copper-transporting ATPase signature 642 659 4.5E-10 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00943 Copper-transporting ATPase signature 449 464 4.5E-10 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00943 Copper-transporting ATPase signature 83 103 4.5E-10 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00943 Copper-transporting ATPase signature 387 401 4.5E-10 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 PRINTS PR00943 Copper-transporting ATPase signature 254 272 4.5E-10 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 Gene3D G3DSA:3.30.70.100 43 106 1.2E-16 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 Gene3D G3DSA:2.70.150.20 257 369 7.2E-41 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 Pfam PF00702 haloacid dehalogenase-like hydrolase 462 679 1.6E-42 T 13-10-2018 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 SUPERFAMILY SSF55008 42 109 2.36E-16 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 SUPERFAMILY SSF56784 466 771 4.62E-59 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 Gene3D G3DSA:3.40.1110.10 477 597 1.5E-93 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 Pfam PF00403 Heavy-metal-associated domain 45 101 1.3E-13 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MADE_1001720 cb1de8aa880efb79276ef8ad276d7ee0 782 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 179 775 4.7E-185 T 13-10-2018 MADE_1015250 c6c81106653ac02e485f61f587070786 246 Pfam PF00462 Glutaredoxin 177 235 4.1E-17 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MADE_1015250 c6c81106653ac02e485f61f587070786 246 PRINTS PR00160 Glutaredoxin signature 232 245 2.2E-15 T 13-10-2018 IPR014025 Glutaredoxin subgroup MADE_1015250 c6c81106653ac02e485f61f587070786 246 PRINTS PR00160 Glutaredoxin signature 218 231 2.2E-15 T 13-10-2018 IPR014025 Glutaredoxin subgroup MADE_1015250 c6c81106653ac02e485f61f587070786 246 PRINTS PR00160 Glutaredoxin signature 177 195 2.2E-15 T 13-10-2018 IPR014025 Glutaredoxin subgroup MADE_1015250 c6c81106653ac02e485f61f587070786 246 Gene3D G3DSA:3.40.30.10 8 169 2.3E-60 T 13-10-2018 MADE_1015250 c6c81106653ac02e485f61f587070786 246 Pfam PF08534 Redoxin 9 164 8.8E-33 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MADE_1015250 c6c81106653ac02e485f61f587070786 246 Gene3D G3DSA:3.40.30.10 177 246 1.8E-23 T 13-10-2018 MADE_1015250 c6c81106653ac02e485f61f587070786 246 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 169 246 5.0E-35 T 13-10-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 MADE_1015250 c6c81106653ac02e485f61f587070786 246 SUPERFAMILY SSF52833 8 245 2.4E-43 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1007010 16b794e34a1921c11691c022ff443ce8 477 Gene3D G3DSA:3.40.50.1820 119 454 6.3E-106 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007010 16b794e34a1921c11691c022ff443ce8 477 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 101 470 21.223 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MADE_1007010 16b794e34a1921c11691c022ff443ce8 477 SUPERFAMILY SSF53474 102 470 2.44E-67 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007010 16b794e34a1921c11691c022ff443ce8 477 Pfam PF00561 alpha/beta hydrolase fold 205 359 2.1E-11 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1007010 16b794e34a1921c11691c022ff443ce8 477 Gene3D G3DSA:1.10.1740.110 283 390 6.3E-106 T 13-10-2018 MADE_1007010 16b794e34a1921c11691c022ff443ce8 477 PIRSF PIRSF000443 70 477 7.6E-101 T 13-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SUPERFAMILY SSF52172 779 900 7.26E-32 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Gene3D G3DSA:1.10.287.130 511 597 5.9E-26 T 13-10-2018 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SUPERFAMILY SSF47226 878 1022 1.1E-13 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF00072 Response regulator receiver domain 781 895 1.3E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Gene3D G3DSA:1.20.120.160 925 1039 7.9E-10 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SMART SM00388 534 599 7.7E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Gene3D G3DSA:3.30.565.10 598 759 1.2E-48 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 394 521 5.4E-11 T 13-10-2018 IPR000014 PAS domain MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 393 1.1E-20 T 13-10-2018 IPR000014 PAS domain MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF00512 His Kinase A (phospho-acceptor) domain 535 599 9.9E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 647 756 1.3E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SUPERFAMILY SSF55874 588 755 6.81E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Gene3D G3DSA:3.30.450.20 267 388 2.6E-24 T 13-10-2018 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SMART SM00091 270 336 5.4E-8 T 13-10-2018 IPR000014 PAS domain MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SMART SM00091 398 470 0.028 T 13-10-2018 IPR000014 PAS domain MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SUPERFAMILY SSF55785 385 512 3.35E-20 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SMART SM00448 779 895 3.7E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Gene3D G3DSA:3.40.50.2300 773 899 3.9E-34 T 13-10-2018 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF01627 Hpt domain 948 1024 1.0E-7 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF08447 PAS fold 423 507 5.1E-16 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SUPERFAMILY SSF47384 518 600 1.31E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SUPERFAMILY SSF55785 281 395 1.95E-19 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SMART SM00387 646 757 2.9E-38 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF03707 Bacterial signalling protein N terminal repeat 66 122 1.2E-16 T 13-10-2018 IPR005330 MHYT domain MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF03707 Bacterial signalling protein N terminal repeat 129 174 3.3E-11 T 13-10-2018 IPR005330 MHYT domain MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF03707 Bacterial signalling protein N terminal repeat 199 248 2.1E-8 T 13-10-2018 IPR005330 MHYT domain MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 682 696 2.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 741 754 2.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 700 710 2.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 PRINTS PR00344 Bacterial sensor protein C-terminal signature 717 735 2.8E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SMART SM00086 346 386 190.0 T 13-10-2018 IPR001610 PAC motif MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 SMART SM00086 472 514 7.1E-8 T 13-10-2018 IPR001610 PAC motif MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Gene3D G3DSA:3.30.450.20 396 510 3.6E-24 T 13-10-2018 MADE_1008900 ed6818c98f1738c546415864c425d32c 1111 Pfam PF13426 PAS domain 281 379 2.3E-9 T 13-10-2018 IPR000014 PAS domain MADE_1000915 d959a630fd63a3f30470a6cb109a24b9 326 PRINTS PR01270 Histone deacetylase superfamily signature 137 160 5.2E-17 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MADE_1000915 d959a630fd63a3f30470a6cb109a24b9 326 PRINTS PR01270 Histone deacetylase superfamily signature 248 258 5.2E-17 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MADE_1000915 d959a630fd63a3f30470a6cb109a24b9 326 PRINTS PR01270 Histone deacetylase superfamily signature 171 186 5.2E-17 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MADE_1000915 d959a630fd63a3f30470a6cb109a24b9 326 Pfam PF00850 Histone deacetylase domain 20 317 6.9E-78 T 13-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MADE_1000915 d959a630fd63a3f30470a6cb109a24b9 326 SUPERFAMILY SSF52768 8 319 1.2E-91 T 13-10-2018 IPR023696 Ureohydrolase domain superfamily MADE_1000915 d959a630fd63a3f30470a6cb109a24b9 326 Gene3D G3DSA:3.40.800.20 1 320 4.5E-106 T 13-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 MADE_1006630 33fa7a71987ee6d8ca7ebabaec63a152 237 SUPERFAMILY SSF48150 11 208 6.44E-57 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MADE_1006630 33fa7a71987ee6d8ca7ebabaec63a152 237 SMART SM00478 46 193 1.2E-43 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MADE_1006630 33fa7a71987ee6d8ca7ebabaec63a152 237 Gene3D G3DSA:1.10.1670.10 20 208 8.9E-63 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 MADE_1006630 33fa7a71987ee6d8ca7ebabaec63a152 237 Hamap MF_00942 Endonuclease III [nth]. 8 217 32.379 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 MADE_1006630 33fa7a71987ee6d8ca7ebabaec63a152 237 PIRSF PIRSF001435 7 215 7.5E-42 T 13-10-2018 MADE_1006630 33fa7a71987ee6d8ca7ebabaec63a152 237 Gene3D G3DSA:1.10.340.30 29 140 8.9E-63 T 13-10-2018 MADE_1006630 33fa7a71987ee6d8ca7ebabaec63a152 237 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 42 176 4.1E-19 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 MADE_1006980 6974967fdaf56369207f9e5dff352340 561 SUPERFAMILY SSF52540 1 220 5.67E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006980 6974967fdaf56369207f9e5dff352340 561 Gene3D G3DSA:3.40.50.300 1 266 2.2E-45 T 13-10-2018 MADE_1006980 6974967fdaf56369207f9e5dff352340 561 Gene3D G3DSA:3.40.50.300 328 557 2.6E-43 T 13-10-2018 MADE_1006980 6974967fdaf56369207f9e5dff352340 561 SUPERFAMILY SSF52540 4 507 3.85E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006980 6974967fdaf56369207f9e5dff352340 561 PIRSF PIRSF003128 1 560 1.8E-152 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MADE_1006980 6974967fdaf56369207f9e5dff352340 561 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 516 1.6E-23 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MADE_1006980 6974967fdaf56369207f9e5dff352340 561 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 556 2.6E-167 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 MADE_1009755 eced67be5c520492055a25754b29335b 335 SMART SM00829 19 331 5.1E-45 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1009755 eced67be5c520492055a25754b29335b 335 SUPERFAMILY SSF51735 125 302 9.7E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009755 eced67be5c520492055a25754b29335b 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 94 1.9E-8 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1009755 eced67be5c520492055a25754b29335b 335 Gene3D G3DSA:3.90.180.10 29 319 2.6E-100 T 13-10-2018 MADE_1009755 eced67be5c520492055a25754b29335b 335 SUPERFAMILY SSF50129 7 157 2.13E-37 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1009755 eced67be5c520492055a25754b29335b 335 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 153 174 - T 13-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MADE_1009755 eced67be5c520492055a25754b29335b 335 Pfam PF00107 Zinc-binding dehydrogenase 164 257 9.0E-21 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1009755 eced67be5c520492055a25754b29335b 335 Gene3D G3DSA:3.40.50.720 133 301 2.6E-100 T 13-10-2018 MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 SUPERFAMILY SSF55326 3 136 1.48E-34 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 SUPERFAMILY SSF56042 142 303 1.64E-41 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 27 135 8.1E-24 T 13-10-2018 IPR016188 PurM-like, N-terminal domain MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 Gene3D G3DSA:3.30.1330.10 1 141 1.2E-45 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 148 297 2.3E-9 T 13-10-2018 IPR010918 PurM-like, C-terminal domain MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 320 28.876 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 Gene3D G3DSA:3.90.650.10 143 320 1.3E-54 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 319 4.1E-110 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MADE_1012425 8dd8feccc0d6e62a1e4ff73a37e4ba48 321 PIRSF PIRSF005303 1 320 9.9E-93 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 Gene3D G3DSA:3.40.50.300 1 203 1.8E-70 T 13-10-2018 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 1.3E-234 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 1.7E-33 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 3.6E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 Gene3D G3DSA:2.40.30.10 338 393 1.2E-29 T 13-10-2018 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 SUPERFAMILY SSF50447 205 301 2.95E-30 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 SUPERFAMILY SSF50465 298 393 8.06E-36 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 60.692 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 7.2E-58 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 SUPERFAMILY SSF52540 9 226 3.84E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 Gene3D G3DSA:2.40.30.10 206 334 2.0E-53 T 13-10-2018 MADE_000001023185 40cb5663babe27a8bde00928d1a806dc 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 151 5.6E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 Gene3D G3DSA:3.40.50.300 1 203 1.8E-70 T 13-10-2018 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 1.3E-234 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 1.7E-33 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 3.6E-17 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 Gene3D G3DSA:2.40.30.10 338 393 1.2E-29 T 13-10-2018 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 SUPERFAMILY SSF50447 205 301 2.95E-30 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 SUPERFAMILY SSF50465 298 393 8.06E-36 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.1E-23 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 60.692 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 7.2E-58 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 SUPERFAMILY SSF52540 9 226 3.84E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 Gene3D G3DSA:2.40.30.10 206 334 2.0E-53 T 13-10-2018 MADE_1018535 40cb5663babe27a8bde00928d1a806dc 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 151 5.6E-14 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1001430 992c28743caf44362b067fc35bcec9d0 135 Pfam PF10980 Protein of unknown function (DUF2787) 16 133 6.1E-37 T 13-10-2018 IPR021248 Protein of unknown function DUF2787 MADE_1001430 992c28743caf44362b067fc35bcec9d0 135 Gene3D G3DSA:3.10.450.430 1 135 1.8E-43 T 13-10-2018 MADE_1002535 336e88a8502d10d8f252b3178804084b 273 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 32 265 1.0E-45 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 MADE_1002535 336e88a8502d10d8f252b3178804084b 273 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 61 245 3.5E-26 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 Gene3D G3DSA:3.30.930.10 8 211 6.2E-59 T 13-10-2018 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 Hamap MF_00013 Octanoyltransferase [lipB]. 12 213 36.055 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 PIRSF PIRSF016262 10 223 2.1E-57 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 SUPERFAMILY SSF55681 10 212 1.66E-66 T 13-10-2018 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 34 189 1.9E-68 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 Pfam PF03099 Biotin/lipoate A/B protein ligase family 69 166 5.6E-5 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 78 93 - T 13-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 MADE_000001021790 f886a5e70f897fe6d5c222a2f3d5c71d 223 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 82 135 7.0E-16 T 13-10-2018 MADE_1008760 c2bc33fd74d0c98fd60d4750600b284f 121 Pfam PF09685 Domain of unknown function (DUF4870) 14 119 1.9E-28 T 13-10-2018 IPR019109 Protein of unknown function DUF4870 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Gene3D G3DSA:3.30.70.240 393 486 1.8E-130 T 13-10-2018 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 SUPERFAMILY SSF50447 155 303 2.65E-33 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 SUPERFAMILY SSF54980 306 391 3.6E-14 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 154 4.4E-26 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Gene3D G3DSA:2.40.50.250 487 603 1.8E-130 T 13-10-2018 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Pfam PF00679 Elongation factor G C-terminus 401 481 6.2E-23 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Pfam PF03144 Elongation factor Tu domain 2 223 293 3.3E-8 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Gene3D G3DSA:2.40.30.10 203 303 2.1E-33 T 13-10-2018 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Gene3D G3DSA:3.40.50.300 6 202 1.4E-69 T 13-10-2018 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Gene3D G3DSA:3.30.70.870 310 594 1.8E-130 T 13-10-2018 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 PRINTS PR00315 GTP-binding elongation factor signature 55 63 2.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 PRINTS PR00315 GTP-binding elongation factor signature 75 85 2.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 PRINTS PR00315 GTP-binding elongation factor signature 127 136 2.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 PRINTS PR00315 GTP-binding elongation factor signature 91 102 2.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 PRINTS PR00315 GTP-binding elongation factor signature 11 24 2.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 SUPERFAMILY SSF54980 402 516 5.28E-28 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 SUPERFAMILY SSF52540 5 211 6.95E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 Pfam PF00009 Elongation factor Tu GTP binding domain 8 198 7.3E-57 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1015975 0d6620dd8b3693d9612d522dc7e9a0e1 610 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 9 603 7.4E-293 T 13-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 Gene3D G3DSA:1.10.8.410 266 319 2.1E-22 T 13-10-2018 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 Gene3D G3DSA:1.20.1330.10 45 171 1.3E-72 T 13-10-2018 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 Gene3D G3DSA:2.30.220.10 186 196 1.3E-72 T 13-10-2018 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 Gene3D G3DSA:2.170.280.10 172 185 1.3E-72 T 13-10-2018 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 Gene3D G3DSA:1.20.58.1830 5 33 1.3E-72 T 13-10-2018 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 SUPERFAMILY SSF64518 1 319 1.19E-90 T 13-10-2018 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 Pfam PF00700 Bacterial flagellin C-terminal helical region 236 318 8.0E-24 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 PRINTS PR00207 Flagellin signature 111 134 3.6E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 PRINTS PR00207 Flagellin signature 76 95 3.6E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 PRINTS PR00207 Flagellin signature 37 54 3.6E-24 T 13-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 MADE_1005760 c973b9608ebf733aaf7e296db74be93d 319 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 2.8E-41 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 Pfam PF00709 Adenylosuccinate synthetase 5 424 6.1E-178 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 SMART SM00788 4 425 8.1E-298 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 Gene3D G3DSA:3.90.170.10 267 432 1.0E-68 T 13-10-2018 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 Gene3D G3DSA:3.40.440.10 6 249 1.7E-103 T 13-10-2018 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 SUPERFAMILY SSF52540 3 430 4.78E-179 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 13-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 Gene3D G3DSA:1.10.300.10 102 201 1.7E-103 T 13-10-2018 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 430 3.4E-193 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 216.862 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MADE_1002935 1799e3f25e3051c8c9d36b18ba555e04 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 13-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 MADE_1005640 f4050b53e03794baa641cd980dbc5580 233 Pfam PF00817 impB/mucB/samB family 2 67 4.3E-7 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MADE_1005640 f4050b53e03794baa641cd980dbc5580 233 Pfam PF11799 impB/mucB/samB family C-terminal domain 157 214 4.3E-5 T 13-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MADE_1005640 f4050b53e03794baa641cd980dbc5580 233 Gene3D G3DSA:3.30.70.270 1 71 2.2E-11 T 13-10-2018 MADE_1005640 f4050b53e03794baa641cd980dbc5580 233 Gene3D G3DSA:1.10.150.20 86 144 1.6E-6 T 13-10-2018 MADE_1005640 f4050b53e03794baa641cd980dbc5580 233 SUPERFAMILY SSF56672 1 152 1.67E-31 T 13-10-2018 MADE_1006125 875c86f766091d28e0d19468445625d8 376 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 370 3.1E-168 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 MADE_1006125 875c86f766091d28e0d19468445625d8 376 PIRSF PIRSF015658 1 376 1.4E-174 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 MADE_1006125 875c86f766091d28e0d19468445625d8 376 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 374 2.2E-157 T 13-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 4 387 34.25 T 13-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 SUPERFAMILY SSF48452 37 246 1.76E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 SMART SM00028 216 249 64.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 SMART SM00028 69 102 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 SMART SM00028 107 140 370.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 SMART SM00028 182 215 160.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 SMART SM00028 282 315 86.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 Gene3D G3DSA:1.25.40.10 21 348 1.2E-29 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1010730 6d680fe7c29e3270e690c733be020759 389 SUPERFAMILY SSF48452 187 325 1.47E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Pfam PF00476 DNA polymerase family A 551 928 1.7E-160 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Gene3D G3DSA:3.30.70.370 665 926 1.1E-116 T 13-10-2018 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Gene3D G3DSA:3.40.50.1010 10 284 2.3E-95 T 13-10-2018 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SMART SM00279 173 208 4.7E-10 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 ProSitePatterns PS00447 DNA polymerase family A signature. 755 774 - T 13-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 9 170 7.0E-56 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SUPERFAMILY SSF47807 171 293 8.22E-28 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 TIGRFAM TIGR00593 pola: DNA polymerase I 10 930 3.9E-290 T 13-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SUPERFAMILY SSF88723 3 170 3.36E-58 T 13-10-2018 IPR029060 PIN-like domain superfamily MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Pfam PF01612 3'-5' exonuclease 331 517 4.3E-42 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SUPERFAMILY SSF56672 523 930 1.11E-161 T 13-10-2018 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SUPERFAMILY SSF53098 334 519 2.32E-58 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SMART SM00474 331 518 1.3E-40 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Gene3D G3DSA:1.10.150.20 710 853 1.1E-116 T 13-10-2018 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Gene3D G3DSA:1.20.1060.10 544 659 7.1E-43 T 13-10-2018 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Gene3D G3DSA:3.30.420.10 328 543 4.1E-69 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 656 678 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 731 744 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 755 780 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 877 890 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 679 694 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 701 724 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 792 803 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 814 825 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 PRINTS PR00868 DNA-polymerase family A (pol I) signature 846 862 5.9E-80 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 271 1.0E-26 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 Gene3D G3DSA:1.10.150.20 174 253 2.3E-95 T 13-10-2018 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SMART SM00475 5 268 4.6E-121 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 MADE_1000075 d0c191095d381969d3d6866b82c208b9 930 SMART SM00482 687 894 1.9E-120 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_000001022840 dfec73d3a733c25a077f7acf8583f472 330 Pfam PF03466 LysR substrate binding domain 89 172 3.5E-10 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_000001022840 dfec73d3a733c25a077f7acf8583f472 330 Gene3D G3DSA:3.40.190.10 92 160 1.4E-9 T 13-10-2018 MADE_000001022840 dfec73d3a733c25a077f7acf8583f472 330 Gene3D G3DSA:3.40.190.10 161 280 1.4E-9 T 13-10-2018 MADE_000001022840 dfec73d3a733c25a077f7acf8583f472 330 SUPERFAMILY SSF53850 87 318 1.03E-15 T 13-10-2018 MADE_000001022840 dfec73d3a733c25a077f7acf8583f472 330 SUPERFAMILY SSF46785 2 110 3.03E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001022840 dfec73d3a733c25a077f7acf8583f472 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.8E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_000001022840 dfec73d3a733c25a077f7acf8583f472 330 Gene3D G3DSA:1.10.10.10 5 70 6.7E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015890 f17da89afd7e166107ec0a4271a978b5 190 SUPERFAMILY SSF47616 86 180 5.27E-8 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1015890 f17da89afd7e166107ec0a4271a978b5 190 SUPERFAMILY SSF52833 1 78 1.1E-15 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1015890 f17da89afd7e166107ec0a4271a978b5 190 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 72 1.2E-11 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1015890 f17da89afd7e166107ec0a4271a978b5 190 Gene3D G3DSA:1.20.1050.10 78 180 1.2E-7 T 13-10-2018 MADE_1015890 f17da89afd7e166107ec0a4271a978b5 190 Gene3D G3DSA:3.40.30.10 1 77 1.9E-17 T 13-10-2018 MADE_1006840 e679105e9afc98631e7ccdfca7216710 122 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 7 106 5.6E-21 T 13-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1006840 e679105e9afc98631e7ccdfca7216710 122 TIGRFAM TIGR00526 folB_dom: FolB domain 7 119 4.0E-34 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1006840 e679105e9afc98631e7ccdfca7216710 122 Pfam PF02152 Dihydroneopterin aldolase 8 116 5.1E-28 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1006840 e679105e9afc98631e7ccdfca7216710 122 SMART SM00905 8 118 2.3E-33 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 MADE_1006840 e679105e9afc98631e7ccdfca7216710 122 SUPERFAMILY SSF55620 5 116 7.23E-30 T 13-10-2018 MADE_1006840 e679105e9afc98631e7ccdfca7216710 122 Gene3D G3DSA:3.30.1130.10 1 120 9.8E-42 T 13-10-2018 MADE_1007655 b91ac9cc1935b3b25cab0d6706a268cf 521 Pfam PF00072 Response regulator receiver domain 24 134 1.4E-8 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007655 b91ac9cc1935b3b25cab0d6706a268cf 521 SUPERFAMILY SSF109604 349 505 1.1E-25 T 13-10-2018 MADE_1007655 b91ac9cc1935b3b25cab0d6706a268cf 521 Pfam PF13487 HD domain 396 458 4.1E-16 T 13-10-2018 MADE_1007655 b91ac9cc1935b3b25cab0d6706a268cf 521 Pfam PF11849 Domain of unknown function (DUF3369) 144 319 1.7E-45 T 13-10-2018 IPR021800 Domain of unknown function DUF3369 MADE_1007655 b91ac9cc1935b3b25cab0d6706a268cf 521 Gene3D G3DSA:1.10.3210.10 319 521 8.5E-56 T 13-10-2018 MADE_1007655 b91ac9cc1935b3b25cab0d6706a268cf 521 SUPERFAMILY SSF52172 18 152 9.11E-14 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1007655 b91ac9cc1935b3b25cab0d6706a268cf 521 Gene3D G3DSA:3.40.50.2300 21 168 2.5E-15 T 13-10-2018 MADE_1009110 106c21a114d573a9081a313ef406d91f 123 Gene3D G3DSA:3.30.70.270 1 123 1.9E-30 T 13-10-2018 MADE_1009110 106c21a114d573a9081a313ef406d91f 123 SUPERFAMILY SSF55073 2 122 3.22E-24 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1009110 106c21a114d573a9081a313ef406d91f 123 Pfam PF00990 Diguanylate cyclase, GGDEF domain 2 119 2.9E-23 T 13-10-2018 IPR000160 GGDEF domain MADE_1009110 106c21a114d573a9081a313ef406d91f 123 SMART SM00267 1 123 2.0E-5 T 13-10-2018 IPR000160 GGDEF domain MADE_1009110 106c21a114d573a9081a313ef406d91f 123 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 2 121 3.7E-24 T 13-10-2018 IPR000160 GGDEF domain MADE_1012110 076893468a9c649ed91bbaf528ba7443 201 SUPERFAMILY SSF46689 7 77 5.2E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1012110 076893468a9c649ed91bbaf528ba7443 201 Gene3D G3DSA:1.10.357.10 2 200 4.0E-53 T 13-10-2018 MADE_1012110 076893468a9c649ed91bbaf528ba7443 201 SUPERFAMILY SSF48498 89 196 1.2E-19 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MADE_1012110 076893468a9c649ed91bbaf528ba7443 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 5.3E-12 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1012110 076893468a9c649ed91bbaf528ba7443 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 8.3E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1012110 076893468a9c649ed91bbaf528ba7443 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.3E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1012110 076893468a9c649ed91bbaf528ba7443 201 Pfam PF13305 WHG domain 92 178 3.0E-14 T 13-10-2018 IPR025996 WHG domain MADE_000001022490 e9691eb39eef0c4726669cc92013a728 59 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 1 47 1.2E-14 T 13-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype MADE_000001022490 e9691eb39eef0c4726669cc92013a728 59 Gene3D G3DSA:3.30.70.240 1 36 2.3E-9 T 13-10-2018 MADE_000001022490 e9691eb39eef0c4726669cc92013a728 59 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 1 47 5.5E-16 T 13-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 SMART SM00267 835 1005 9.7E-56 T 13-10-2018 IPR000160 GGDEF domain MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 SUPERFAMILY SSF63829 347 656 2.94E-11 T 13-10-2018 MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 SUPERFAMILY SSF63829 117 350 4.25E-12 T 13-10-2018 MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 Gene3D G3DSA:2.130.10.10 496 664 4.3E-13 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 Gene3D G3DSA:2.130.10.10 51 356 4.8E-51 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 Pfam PF07495 Y_Y_Y domain 723 784 6.7E-16 T 13-10-2018 IPR011123 Two component regulator three Y MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 Gene3D G3DSA:3.30.70.270 832 1004 1.8E-54 T 13-10-2018 MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 Gene3D G3DSA:2.60.40.10 666 790 1.3E-29 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 843 1004 1.8E-50 T 13-10-2018 IPR000160 GGDEF domain MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 Gene3D G3DSA:2.130.10.10 369 495 3.6E-14 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 SUPERFAMILY SSF55073 851 1004 6.04E-46 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1008750 03d9412e8fdd4061dc87ab9b22f7cd5e 1005 Pfam PF00990 Diguanylate cyclase, GGDEF domain 847 1001 4.1E-48 T 13-10-2018 IPR000160 GGDEF domain MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 SMART SM00842 10 196 3.0E-99 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 SUPERFAMILY SSF53067 8 221 1.78E-57 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Gene3D G3DSA:3.90.640.10 235 300 4.8E-120 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 378 3.8E-154 T 13-10-2018 IPR020823 Cell division protein FtsA MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Pfam PF14450 Cell division protein FtsA 11 187 8.3E-8 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 8.4E-32 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Gene3D G3DSA:3.30.420.40 197 352 4.8E-120 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Gene3D G3DSA:3.30.420.40 13 372 4.8E-120 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Gene3D G3DSA:3.30.1490.110 87 169 4.8E-120 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 409 29.779 T 13-10-2018 IPR020823 Cell division protein FtsA MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 Pfam PF14450 Cell division protein FtsA 207 374 6.8E-24 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 SUPERFAMILY SSF53067 198 377 9.09E-48 T 13-10-2018 MADE_000001022605 cb4746fda9129c7d27ae146b33fe7839 409 PIRSF PIRSF003101 1 409 2.3E-153 T 13-10-2018 IPR020823 Cell division protein FtsA MADE_1006660 22628b5def1192bfe7b34c3440923afd 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 190 5.4E-59 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_1006660 22628b5def1192bfe7b34c3440923afd 193 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 2 191 25.878 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 MADE_1006660 22628b5def1192bfe7b34c3440923afd 193 PIRSF PIRSF006102 1 193 4.4E-59 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_1006660 22628b5def1192bfe7b34c3440923afd 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 9.4E-87 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 MADE_1012235 d324af263626a0b08a28bef433a50e09 639 Pfam PF13307 Helicase C-terminal domain 461 618 1.2E-33 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MADE_1012235 d324af263626a0b08a28bef433a50e09 639 SMART SM00487 19 323 1.1E-4 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1012235 d324af263626a0b08a28bef433a50e09 639 Gene3D G3DSA:3.40.50.300 22 281 1.3E-47 T 13-10-2018 MADE_1012235 d324af263626a0b08a28bef433a50e09 639 SMART SM00491 477 606 1.6E-41 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 MADE_1012235 d324af263626a0b08a28bef433a50e09 639 SMART SM00488 21 270 0.0027 T 13-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 MADE_1012235 d324af263626a0b08a28bef433a50e09 639 SUPERFAMILY SSF52540 190 594 1.43E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012235 d324af263626a0b08a28bef433a50e09 639 Gene3D G3DSA:3.40.50.300 443 637 1.5E-37 T 13-10-2018 MADE_1012235 d324af263626a0b08a28bef433a50e09 639 SUPERFAMILY SSF52540 18 602 7.62E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 2.2E-38 T 13-10-2018 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 PRINTS PR00173 Glutamate-aspartate symporter signature 345 364 2.2E-38 T 13-10-2018 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 PRINTS PR00173 Glutamate-aspartate symporter signature 208 227 2.2E-38 T 13-10-2018 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 PRINTS PR00173 Glutamate-aspartate symporter signature 98 123 2.2E-38 T 13-10-2018 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 PRINTS PR00173 Glutamate-aspartate symporter signature 372 392 2.2E-38 T 13-10-2018 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 PRINTS PR00173 Glutamate-aspartate symporter signature 310 336 2.2E-38 T 13-10-2018 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 Gene3D G3DSA:1.10.3860.10 1 435 4.0E-138 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 SUPERFAMILY SSF118215 10 419 9.02E-121 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MADE_000001021565 3c67d945d972c8d919e176df6b039791 448 Pfam PF00375 Sodium:dicarboxylate symporter family 10 417 3.0E-131 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MADE_1010360 70fa6164f23c73e6134c6de9ad766bd5 396 Gene3D G3DSA:1.10.443.10 175 382 5.1E-39 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1010360 70fa6164f23c73e6134c6de9ad766bd5 396 Gene3D G3DSA:1.10.150.130 64 164 1.9E-11 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1010360 70fa6164f23c73e6134c6de9ad766bd5 396 SUPERFAMILY SSF56349 174 388 2.85E-36 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1010360 70fa6164f23c73e6134c6de9ad766bd5 396 Pfam PF00589 Phage integrase family 181 380 1.4E-19 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1010360 70fa6164f23c73e6134c6de9ad766bd5 396 SUPERFAMILY SSF47823 75 150 7.06E-11 T 13-10-2018 MADE_000001023055 dacf61a8f11693871c7eb343acf7b001 403 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 5 77 6.0E-20 T 13-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 MADE_000001023055 dacf61a8f11693871c7eb343acf7b001 403 Pfam PF07670 Nucleoside recognition 89 185 5.1E-9 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 MADE_000001023055 dacf61a8f11693871c7eb343acf7b001 403 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 191 398 1.9E-73 T 13-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 MADE_000001023055 dacf61a8f11693871c7eb343acf7b001 403 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 1 399 3.3E-146 T 13-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 MADE_1020380 4b785bc4948a8d0bfb4d0426e944d554 449 Pfam PF13657 HipA N-terminal domain 22 120 3.3E-15 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 MADE_1020380 4b785bc4948a8d0bfb4d0426e944d554 449 Pfam PF07804 HipA-like C-terminal domain 178 414 1.1E-37 T 13-10-2018 IPR012893 HipA-like, C-terminal MADE_1003710 323589bf00e0cf0a55cacba97710ffb1 313 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 64 78 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003710 323589bf00e0cf0a55cacba97710ffb1 313 Gene3D G3DSA:3.40.1010.10 57 174 5.3E-39 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MADE_1003710 323589bf00e0cf0a55cacba97710ffb1 313 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 59 296 4.1E-78 T 13-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 MADE_1003710 323589bf00e0cf0a55cacba97710ffb1 313 SUPERFAMILY SSF53790 57 300 1.22E-67 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MADE_1003710 323589bf00e0cf0a55cacba97710ffb1 313 Gene3D G3DSA:3.30.950.10 175 304 2.3E-38 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 MADE_1003710 323589bf00e0cf0a55cacba97710ffb1 313 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 61 272 9.0E-49 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 SUPERFAMILY SSF54211 255 454 3.79E-43 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 Gene3D G3DSA:3.30.230.10 309 455 5.1E-22 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 PRINTS PR01874 DNA repair protein radA signature 10 34 5.9E-94 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 PRINTS PR01874 DNA repair protein radA signature 322 345 5.9E-94 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 PRINTS PR01874 DNA repair protein radA signature 248 274 5.9E-94 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 PRINTS PR01874 DNA repair protein radA signature 174 198 5.9E-94 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 PRINTS PR01874 DNA repair protein radA signature 83 111 5.9E-94 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 PRINTS PR01874 DNA repair protein radA signature 124 141 5.9E-94 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 PRINTS PR01874 DNA repair protein radA signature 213 241 5.9E-94 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 Pfam PF13481 AAA domain 75 222 4.9E-10 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 SUPERFAMILY SSF52540 68 292 2.47E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 Gene3D G3DSA:3.40.50.300 67 279 5.6E-37 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 SMART SM00382 91 244 7.5E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 Pfam PF13541 Subunit ChlI of Mg-chelatase 346 430 6.2E-10 T 13-10-2018 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 451 7.8E-219 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MADE_1012480 ee87715460fe813a688326eeec90a6d5 455 Hamap MF_01498 DNA repair protein RadA [radA]. 21 455 42.808 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 MADE_1011735 9312e2767a6f04d8d9d65c46e06b1c13 199 Pfam PF04972 BON domain 35 101 2.1E-18 T 13-10-2018 IPR007055 BON domain MADE_1011735 9312e2767a6f04d8d9d65c46e06b1c13 199 Pfam PF04972 BON domain 126 193 3.3E-18 T 13-10-2018 IPR007055 BON domain MADE_1011735 9312e2767a6f04d8d9d65c46e06b1c13 199 SMART SM00749 39 102 0.16 T 13-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria MADE_1011735 9312e2767a6f04d8d9d65c46e06b1c13 199 SMART SM00749 131 194 3.9E-7 T 13-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 SUPERFAMILY SSF56601 238 573 3.06E-87 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 SUPERFAMILY SSF56519 66 236 1.7E-43 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 Gene3D G3DSA:3.90.1310.30 62 236 1.5E-43 T 13-10-2018 MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 561 2.1E-64 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 22 577 44.636 T 13-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 Gene3D G3DSA:3.40.710.10 298 484 3.3E-102 T 13-10-2018 MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 Gene3D G3DSA:3.30.450.330 238 565 3.3E-102 T 13-10-2018 MADE_1015180 28550bd00b7e508075bf90a2a39d63d0 590 Pfam PF03717 Penicillin-binding Protein dimerisation domain 72 221 1.2E-18 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 SUPERFAMILY SSF53686 3 426 2.1E-123 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 95 109 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 Gene3D G3DSA:3.40.50.1100 101 399 3.0E-133 T 13-10-2018 MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 Gene3D G3DSA:3.40.50.1100 83 392 3.0E-133 T 13-10-2018 MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 86 367 2.6E-25 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 Gene3D G3DSA:3.90.1380.10 1 79 7.7E-25 T 13-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 Pfam PF14821 Threonine synthase N terminus 8 78 1.0E-10 T 13-10-2018 IPR029144 Threonine synthase, N-terminal MADE_1015470 5d894a9a6700df7eb50be57acaf726da 427 TIGRFAM TIGR00260 thrC: threonine synthase 64 391 6.0E-109 T 13-10-2018 IPR004450 Threonine synthase-like MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 PIRSF PIRSF006614 1 135 7.9E-59 T 13-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 Gene3D G3DSA:3.40.50.1380 1 136 2.8E-58 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 SMART SM00851 17 110 1.2E-20 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 4 123 32.536 T 13-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 SUPERFAMILY SSF52335 3 130 3.2E-51 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 5 124 4.8E-54 T 13-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 Pfam PF02142 MGS-like domain 17 109 9.0E-16 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain MADE_1002670 e7976f96529ee58ab18ce19c70d858ab 136 ProSitePatterns PS01335 Methylglyoxal synthase active site. 57 65 - T 13-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 271 1.4E-23 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 Pfam PF01464 Transglycosylase SLT domain 302 398 5.9E-19 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 SMART SM00062 42 272 4.3E-20 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 SUPERFAMILY SSF53955 293 457 4.1E-32 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 Gene3D G3DSA:1.10.530.10 289 462 2.4E-32 T 13-10-2018 MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 9 463 45.39 T 13-10-2018 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 Gene3D G3DSA:3.40.190.10 39 267 3.8E-54 T 13-10-2018 MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 SUPERFAMILY SSF53850 43 271 3.58E-30 T 13-10-2018 MADE_1005430 767ff04bd12ce3cf1b1bdcf96d169310 463 Gene3D G3DSA:3.40.190.10 127 228 3.8E-54 T 13-10-2018 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 SUPERFAMILY SSF56645 6 249 4.97E-86 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 131 143 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 2.1E-43 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 Gene3D G3DSA:1.10.540.10 2 127 5.7E-46 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 Gene3D G3DSA:2.40.110.10 128 241 7.8E-47 T 13-10-2018 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 Gene3D G3DSA:1.20.140.10 242 389 1.1E-46 T 13-10-2018 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 5.5E-36 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 SUPERFAMILY SSF47203 234 387 4.99E-47 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 PIRSF PIRSF016578 15 100 0.013 T 13-10-2018 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 PIRSF PIRSF016578 135 389 2.0E-10 T 13-10-2018 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 13-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 MADE_1008445 8b2c2224a0caa45478b4ced5701bc7af 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 224 4.1E-26 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1005730 235d36d4c10fd8c3c96eb2524bb44bfa 262 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 261 2.5E-109 T 13-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 MADE_1005730 235d36d4c10fd8c3c96eb2524bb44bfa 262 SUPERFAMILY SSF117143 93 223 7.85E-32 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like MADE_1005730 235d36d4c10fd8c3c96eb2524bb44bfa 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 184 260 6.9E-23 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MADE_1005730 235d36d4c10fd8c3c96eb2524bb44bfa 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 148 244 5.5E-29 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G MADE_1005730 235d36d4c10fd8c3c96eb2524bb44bfa 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 137 8.3E-40 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G MADE_1005730 235d36d4c10fd8c3c96eb2524bb44bfa 262 Pfam PF00460 Flagella basal body rod protein 5 35 8.1E-11 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MADE_1005730 235d36d4c10fd8c3c96eb2524bb44bfa 262 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site MADE_1004385 78db7e02e4892b08e1ac580a2ff4f355 168 Gene3D G3DSA:3.30.70.260 82 167 8.7E-19 T 13-10-2018 MADE_1004385 78db7e02e4892b08e1ac580a2ff4f355 168 SUPERFAMILY SSF55021 3 68 1.14E-9 T 13-10-2018 MADE_1004385 78db7e02e4892b08e1ac580a2ff4f355 168 Gene3D G3DSA:3.30.70.260 1 75 9.6E-15 T 13-10-2018 MADE_1004385 78db7e02e4892b08e1ac580a2ff4f355 168 SUPERFAMILY SSF55021 85 166 1.11E-10 T 13-10-2018 MADE_1004385 78db7e02e4892b08e1ac580a2ff4f355 168 PIRSF PIRSF028103 1 168 6.1E-35 T 13-10-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 MADE_1004385 78db7e02e4892b08e1ac580a2ff4f355 168 Pfam PF13740 ACT domain 3 68 2.1E-8 T 13-10-2018 MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 Pfam PF04675 DNA ligase N terminus 3 156 5.1E-6 T 13-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 224 232 - T 13-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 3 574 6.5E-204 T 13-10-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 SUPERFAMILY SSF50249 455 575 6.34E-32 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 SUPERFAMILY SSF56091 158 451 2.56E-44 T 13-10-2018 MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 Gene3D G3DSA:2.40.50.140 454 576 2.9E-31 T 13-10-2018 MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 Pfam PF01068 ATP dependent DNA ligase domain 203 449 1.9E-24 T 13-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 MADE_000001023455 84291c397388fd639f7e183401b3e0e3 576 Pfam PF04679 ATP dependent DNA ligase C terminal region 470 559 6.8E-12 T 13-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 MADE_1009915 9038caaa6c15e37646489f5093d70ec7 292 SUPERFAMILY SSF53335 9 277 1.93E-76 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1009915 9038caaa6c15e37646489f5093d70ec7 292 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 288 1.4E-58 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MADE_1009915 9038caaa6c15e37646489f5093d70ec7 292 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 274 37.941 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 MADE_1009915 9038caaa6c15e37646489f5093d70ec7 292 Gene3D G3DSA:3.40.50.150 1 292 5.3E-95 T 13-10-2018 MADE_1019195 4d4c1838111e8ae9d520f4f80ce52926 689 Gene3D G3DSA:2.170.130.10 19 161 1.4E-17 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1019195 4d4c1838111e8ae9d520f4f80ce52926 689 Gene3D G3DSA:2.40.170.20 180 688 1.8E-65 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1019195 4d4c1838111e8ae9d520f4f80ce52926 689 SUPERFAMILY SSF56935 20 687 1.25E-96 T 13-10-2018 MADE_1019195 4d4c1838111e8ae9d520f4f80ce52926 689 Pfam PF00593 TonB dependent receptor 173 687 1.1E-43 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1019195 4d4c1838111e8ae9d520f4f80ce52926 689 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 154 1.3E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1008300 ab6903f62abf537aa56f73f929ada649 783 PIRSF PIRSF001227 5 773 7.6E-121 T 13-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 MADE_1008300 ab6903f62abf537aa56f73f929ada649 783 Gene3D G3DSA:1.10.1400.10 542 678 1.0E-96 T 13-10-2018 MADE_1008300 ab6903f62abf537aa56f73f929ada649 783 Pfam PF01804 Penicillin amidase 48 766 4.4E-120 T 13-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 MADE_1008300 ab6903f62abf537aa56f73f929ada649 783 Gene3D G3DSA:2.30.120.10 344 395 1.0E-96 T 13-10-2018 MADE_1008300 ab6903f62abf537aa56f73f929ada649 783 SUPERFAMILY SSF56235 44 770 2.83E-162 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1008300 ab6903f62abf537aa56f73f929ada649 783 Gene3D G3DSA:1.10.439.10 17 178 8.6E-38 T 13-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 MADE_1008300 ab6903f62abf537aa56f73f929ada649 783 Gene3D G3DSA:3.60.20.10 268 759 1.0E-96 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 SUPERFAMILY SSF53850 87 257 1.01E-13 T 13-10-2018 MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 SUPERFAMILY SSF46785 1 83 7.39E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 Gene3D G3DSA:3.40.190.10 158 244 2.8E-10 T 13-10-2018 MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 Pfam PF03466 LysR substrate binding domain 93 236 7.0E-9 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.9E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 Gene3D G3DSA:1.10.10.10 1 90 3.4E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1013675 5d74e59a07a2d460eb28d0f851726179 276 Gene3D G3DSA:3.40.190.10 93 157 2.8E-10 T 13-10-2018 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 2.3E-64 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 Gene3D G3DSA:3.40.47.10 131 387 4.1E-135 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 PIRSF PIRSF000429 1 393 9.1E-116 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 3.9E-43 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 SUPERFAMILY SSF53901 1 265 8.11E-69 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 Gene3D G3DSA:3.40.47.10 6 276 4.1E-135 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 SUPERFAMILY SSF53901 272 392 9.87E-42 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 13-10-2018 IPR020613 Thiolase, conserved site GO:0016747 MADE_1008785 ed06eaef964eabbfcc1e4d71224806b9 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.1E-125 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Pfam PF13185 GAF domain 215 356 1.1E-11 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Gene3D G3DSA:3.30.70.270 366 541 3.6E-61 T 13-10-2018 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 PIRSF PIRSF005925 155 794 1.1E-158 T 13-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SUPERFAMILY SSF55073 373 531 7.85E-49 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SMART SM00267 357 529 2.1E-64 T 13-10-2018 IPR000160 GGDEF domain MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Gene3D G3DSA:3.30.450.40 213 365 3.3E-25 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Gene3D G3DSA:3.30.450.40 40 178 3.6E-18 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SMART SM00065 215 365 3.4E-6 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SMART SM00065 43 184 8.9E-11 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 366 528 1.1E-44 T 13-10-2018 IPR000160 GGDEF domain MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Pfam PF00563 EAL domain 545 781 7.3E-74 T 13-10-2018 IPR001633 EAL domain MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SMART SM00052 539 786 6.3E-99 T 13-10-2018 IPR001633 EAL domain MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SUPERFAMILY SSF55781 45 187 2.18E-24 T 13-10-2018 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SUPERFAMILY SSF141868 545 792 1.44E-83 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1010800 de10169ef30f04a18c2050552d255d89 794 SUPERFAMILY SSF55781 183 357 1.2E-23 T 13-10-2018 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Pfam PF00990 Diguanylate cyclase, GGDEF domain 368 524 4.9E-49 T 13-10-2018 IPR000160 GGDEF domain MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Pfam PF01590 GAF domain 45 172 3.0E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1010800 de10169ef30f04a18c2050552d255d89 794 Gene3D G3DSA:3.20.20.450 542 794 2.0E-92 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 SUPERFAMILY SSF48024 15 126 1.01E-39 T 13-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 SUPERFAMILY SSF52540 193 444 2.02E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 Gene3D G3DSA:3.40.50.300 174 454 5.2E-106 T 13-10-2018 MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 17 453 6.3E-176 T 13-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 SMART SM00382 212 418 2.9E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 Pfam PF00772 DnaB-like helicase N terminal domain 17 118 2.5E-38 T 13-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 Gene3D G3DSA:1.10.860.10 9 173 2.3E-56 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal MADE_000001023625 30a403d68adbea4c3fa91048ccfff840 461 Pfam PF03796 DnaB-like helicase C terminal domain 195 451 1.1E-112 T 13-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 SUPERFAMILY SSF51735 5 253 1.11E-70 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.3E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.3E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.3E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-36 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 4.7E-61 T 13-10-2018 MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.1E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.1E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008770 95ebf02dd13a19fbc9118b39e002bf99 254 Gene3D G3DSA:3.40.50.720 4 253 3.4E-76 T 13-10-2018 MADE_1005510 58921c3155464c4b264af9cca545ee02 139 Pfam PF03203 MerC mercury resistance protein 13 124 3.9E-16 T 13-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 MADE_1005510 58921c3155464c4b264af9cca545ee02 139 ProDom PD007347 MERC PLASMID MEMBRANE INNER UPTAKE MERCURY HGII RESISTANCE PRECURSOR TRANSMEMBRANE 25 137 6.0E-58 T 13-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 MADE_1010915 40ceed56798a501728ada66d4400f546 332 SUPERFAMILY SSF53335 93 325 4.26E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1010915 40ceed56798a501728ada66d4400f546 332 Pfam PF08003 Protein of unknown function (DUF1698) 13 331 5.4E-149 T 13-10-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like MADE_1010915 40ceed56798a501728ada66d4400f546 332 Gene3D G3DSA:3.40.50.150 93 311 1.7E-27 T 13-10-2018 MADE_1010915 40ceed56798a501728ada66d4400f546 332 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 17 331 54.483 T 13-10-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MADE_1010915 40ceed56798a501728ada66d4400f546 332 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 13 330 2.1E-149 T 13-10-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 SUPERFAMILY SSF53163 18 172 2.28E-38 T 13-10-2018 IPR023430 Peptidase HybD-like domain superfamily MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 Gene3D G3DSA:3.40.50.1450 19 177 4.5E-37 T 13-10-2018 IPR023430 Peptidase HybD-like domain superfamily MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 Pfam PF01750 Hydrogenase maturation protease 37 163 8.6E-21 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 22 165 6.0E-35 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 PRINTS PR00446 Hydrogen uptake protein signature 73 83 1.4E-13 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 PRINTS PR00446 Hydrogen uptake protein signature 32 43 1.4E-13 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 PRINTS PR00446 Hydrogen uptake protein signature 20 32 1.4E-13 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 PRINTS PR00446 Hydrogen uptake protein signature 52 69 1.4E-13 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MADE_1001660 8a7afc31871c21aeb0ce395e8c2091c9 184 PRINTS PR00446 Hydrogen uptake protein signature 84 100 1.4E-13 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 MADE_1002505 63673f98c97fe5722694ac924e3f4a3e 345 TIGRFAM TIGR03244 arg_catab_AstA: arginine N-succinyltransferase 3 339 9.1E-144 T 13-10-2018 IPR017650 Arginine N-succinyltransferase GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 MADE_1002505 63673f98c97fe5722694ac924e3f4a3e 345 Gene3D G3DSA:3.40.630.30 2 274 2.0E-118 T 13-10-2018 MADE_1002505 63673f98c97fe5722694ac924e3f4a3e 345 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 339 7.0E-145 T 13-10-2018 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 MADE_1002505 63673f98c97fe5722694ac924e3f4a3e 345 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 3 340 3.7E-141 T 13-10-2018 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 MADE_1002505 63673f98c97fe5722694ac924e3f4a3e 345 SUPERFAMILY SSF55729 1 340 1.45E-135 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1002505 63673f98c97fe5722694ac924e3f4a3e 345 Gene3D G3DSA:2.40.40.20 275 342 1.6E-7 T 13-10-2018 MADE_000001021330 434c04756c016e098019c2a4c1c17c8d 693 SUPERFAMILY SSF56935 17 689 5.29E-112 T 13-10-2018 MADE_000001021330 434c04756c016e098019c2a4c1c17c8d 693 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 52 689 2.1E-83 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MADE_000001021330 434c04756c016e098019c2a4c1c17c8d 693 Gene3D G3DSA:2.40.170.20 160 693 3.0E-97 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_000001021330 434c04756c016e098019c2a4c1c17c8d 693 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 146 5.1E-17 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_000001021330 434c04756c016e098019c2a4c1c17c8d 693 Gene3D G3DSA:2.170.130.10 33 157 3.0E-32 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_000001021330 434c04756c016e098019c2a4c1c17c8d 693 Pfam PF00593 TonB dependent receptor 216 688 2.7E-47 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1000145 4e1f33c6575f8d2eff0ed897db51afcb 143 Gene3D G3DSA:1.10.490.10 16 143 1.9E-39 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MADE_1000145 4e1f33c6575f8d2eff0ed897db51afcb 143 Pfam PF01152 Bacterial-like globin 23 140 1.4E-30 T 13-10-2018 IPR001486 Truncated hemoglobin GO:0019825 MADE_1000145 4e1f33c6575f8d2eff0ed897db51afcb 143 SUPERFAMILY SSF46458 21 141 3.24E-31 T 13-10-2018 IPR009050 Globin-like superfamily MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 Pfam PF13538 UvrD-like helicase C-terminal domain 648 698 2.0E-13 T 13-10-2018 IPR027785 UvrD-like helicase C-terminal domain MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 Pfam PF13245 AAA domain 203 353 1.2E-28 T 13-10-2018 MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 Gene3D G3DSA:3.40.50.300 155 384 4.6E-57 T 13-10-2018 MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 SUPERFAMILY SSF52540 197 703 1.93E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 18 721 44.334 T 13-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 19 720 2.6E-121 T 13-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 Gene3D G3DSA:3.40.50.300 612 712 1.3E-21 T 13-10-2018 MADE_1013625 427a97bdab8e39b691c73d38449857fa 731 Gene3D G3DSA:3.40.50.300 432 597 1.5E-8 T 13-10-2018 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Pfam PF02817 e3 binding domain 373 407 5.2E-16 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 SUPERFAMILY SSF51230 127 219 3.8E-21 T 13-10-2018 IPR011053 Single hybrid motif MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 213 679 1.6E-186 T 13-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 448 678 1.7E-75 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Gene3D G3DSA:2.40.50.100 245 322 6.2E-20 T 13-10-2018 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 SUPERFAMILY SSF47005 366 411 3.79E-13 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 SUPERFAMILY SSF51230 244 336 6.81E-22 T 13-10-2018 IPR011053 Single hybrid motif MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 SUPERFAMILY SSF51230 3 95 4.06E-19 T 13-10-2018 IPR011053 Single hybrid motif MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Gene3D G3DSA:3.30.559.10 432 679 4.3E-94 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Pfam PF00364 Biotin-requiring enzyme 129 200 9.6E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Pfam PF00364 Biotin-requiring enzyme 246 317 6.7E-20 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Pfam PF00364 Biotin-requiring enzyme 6 75 2.9E-16 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Gene3D G3DSA:2.40.50.100 126 204 4.3E-18 T 13-10-2018 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 268 297 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 151 180 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Gene3D G3DSA:4.10.320.10 372 416 1.7E-20 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 Gene3D G3DSA:2.40.50.100 4 80 1.7E-16 T 13-10-2018 MADE_1014975 61832843e51196695fc7d8ce98fd6b8f 679 SUPERFAMILY SSF52777 438 678 1.78E-79 T 13-10-2018 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 PIRSF PIRSF005784 6 191 7.3E-89 T 13-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 6 183 2.2E-87 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 Gene3D G3DSA:1.10.15.40 41 85 1.5E-7 T 13-10-2018 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 Pfam PF04060 Putative Fe-S cluster 47 78 1.7E-14 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 148 159 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 Gene3D G3DSA:3.30.70.20 86 181 3.3E-22 T 13-10-2018 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 Pfam PF14697 4Fe-4S dicluster domain 111 165 1.9E-18 T 13-10-2018 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 7 170 25.724 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 MADE_1006655 c4d563a5aa39a25cb6ba38b4562bfecf 193 SUPERFAMILY SSF54862 41 177 1.47E-31 T 13-10-2018 MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 124 196 3.8E-18 T 13-10-2018 IPR006260 TonB/TolA, C-terminal MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 124 199 2.1E-18 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 PRINTS PR01374 Gram-negative bacterial tonB protein signature 118 139 8.1E-16 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 PRINTS PR01374 Gram-negative bacterial tonB protein signature 61 71 8.1E-16 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 PRINTS PR01374 Gram-negative bacterial tonB protein signature 158 175 8.1E-16 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 PRINTS PR01374 Gram-negative bacterial tonB protein signature 139 157 8.1E-16 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 Gene3D G3DSA:3.30.1150.10 105 202 1.4E-28 T 13-10-2018 MADE_1006270 9b65fdda963e87025b34e5264c37ce31 203 SUPERFAMILY SSF74653 114 193 1.12E-25 T 13-10-2018 MADE_1002720 05a32043fa294935617bb7017d96be9d 141 Gene3D G3DSA:3.40.250.10 22 141 1.5E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1002720 05a32043fa294935617bb7017d96be9d 141 SMART SM00450 40 138 2.3E-18 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1002720 05a32043fa294935617bb7017d96be9d 141 Pfam PF00581 Rhodanese-like domain 44 135 8.4E-19 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1002720 05a32043fa294935617bb7017d96be9d 141 SUPERFAMILY SSF52821 17 140 4.19E-31 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Gene3D G3DSA:1.20.120.160 2 141 3.1E-37 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Gene3D G3DSA:3.30.565.10 424 610 2.5E-56 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Pfam PF01584 CheW-like domain 617 744 5.7E-23 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SUPERFAMILY SSF50341 610 742 4.32E-28 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 364 423 5.0E-14 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SMART SM01231 363 423 2.5E-18 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Gene3D G3DSA:2.30.30.40 611 738 1.2E-33 T 13-10-2018 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SUPERFAMILY SSF47384 364 424 1.37E-14 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Pfam PF01627 Hpt domain 8 103 1.3E-18 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SUPERFAMILY SSF47226 6 125 3.53E-31 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SUPERFAMILY SSF55874 426 609 6.55E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SMART SM00260 603 742 3.2E-33 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SMART SM00387 468 611 3.6E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 589 1.0E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 527 1.0E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 608 1.0E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 565 1.0E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 610 1.2E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Gene3D G3DSA:1.10.287.560 363 423 9.3E-20 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 Gene3D G3DSA:2.40.50.180 634 697 1.2E-33 T 13-10-2018 MADE_1006000 b630f79bc1bdac7ebe2748cf2876c3b5 751 SMART SM00073 6 103 3.7E-23 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1017015 5297e085de81d30a10dec875059a4ff0 178 Pfam PF00258 Flavodoxin 10 169 4.4E-26 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MADE_1017015 5297e085de81d30a10dec875059a4ff0 178 Gene3D G3DSA:3.40.50.360 6 178 3.7E-47 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1017015 5297e085de81d30a10dec875059a4ff0 178 PIRSF PIRSF038996 5 178 2.2E-57 T 13-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 MADE_1017015 5297e085de81d30a10dec875059a4ff0 178 ProSitePatterns PS00201 Flavodoxin signature. 10 26 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MADE_1017015 5297e085de81d30a10dec875059a4ff0 178 TIGRFAM TIGR01752 flav_long: flavodoxin 8 176 3.2E-64 T 13-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 MADE_1017015 5297e085de81d30a10dec875059a4ff0 178 SUPERFAMILY SSF52218 8 173 7.74E-47 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1020305 81506c8a94f995124ca30dd72361cb40 106 SMART SM00530 11 66 6.2E-12 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1020305 81506c8a94f995124ca30dd72361cb40 106 Gene3D G3DSA:1.10.260.40 2 74 4.8E-16 T 13-10-2018 MADE_1020305 81506c8a94f995124ca30dd72361cb40 106 Pfam PF01381 Helix-turn-helix 12 63 7.2E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1020305 81506c8a94f995124ca30dd72361cb40 106 SUPERFAMILY SSF47413 4 63 3.94E-14 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 Gene3D G3DSA:3.30.590.10 105 457 1.8E-148 T 13-10-2018 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 Gene3D G3DSA:3.10.20.70 2 104 1.6E-38 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 13-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 SUPERFAMILY SSF54368 3 100 6.8E-34 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 SUPERFAMILY SSF55931 102 468 2.06E-137 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 SMART SM01230 102 379 3.1E-153 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 Pfam PF00120 Glutamine synthetase, catalytic domain 102 466 5.0E-139 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 95 5.6E-30 T 13-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 468 2.2E-210 T 13-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 13-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 MADE_1015985 39f878a6c8ea1c257fc1ea03b3a5ca75 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 13-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 Hamap MF_01618 3-ketoacyl-CoA thiolase [fadI]. 2 436 67.792 T 13-10-2018 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 Pfam PF00108 Thiolase, N-terminal domain 15 288 4.3E-59 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 TIGRFAM TIGR02446 FadI: acetyl-CoA C-acyltransferase FadI 7 436 2.4E-249 T 13-10-2018 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 SUPERFAMILY SSF53901 296 434 3.84E-31 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 PIRSF PIRSF000429 9 436 6.3E-114 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 17 434 7.8E-126 T 13-10-2018 IPR002155 Thiolase GO:0016747 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 SUPERFAMILY SSF53901 15 294 4.48E-58 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 Gene3D G3DSA:3.40.47.10 6 435 4.5E-109 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 Pfam PF02803 Thiolase, C-terminal domain 295 434 1.2E-36 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 MADE_1006800 d8ed9e4ce29a4df7edf534256319b606 436 ProSitePatterns PS00099 Thiolases active site. 417 430 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 MADE_1015385 4e3e0d02c29fd63b12e8e43a7bea38a3 210 SUPERFAMILY SSF52833 1 84 2.74E-23 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1015385 4e3e0d02c29fd63b12e8e43a7bea38a3 210 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 74 1.1E-15 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1015385 4e3e0d02c29fd63b12e8e43a7bea38a3 210 SUPERFAMILY SSF47616 81 201 1.95E-18 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1015385 4e3e0d02c29fd63b12e8e43a7bea38a3 210 Gene3D G3DSA:3.40.30.10 4 196 2.1E-46 T 13-10-2018 MADE_1015385 4e3e0d02c29fd63b12e8e43a7bea38a3 210 Pfam PF00043 Glutathione S-transferase, C-terminal domain 113 194 2.4E-6 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal MADE_1015385 4e3e0d02c29fd63b12e8e43a7bea38a3 210 Gene3D G3DSA:1.20.1050.10 82 193 2.1E-46 T 13-10-2018 MADE_1004235 cc4433f88ddc215e31232bfa14bee229 221 PIRSF PIRSF004649 1 212 6.5E-63 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MADE_1004235 cc4433f88ddc215e31232bfa14bee229 221 Gene3D G3DSA:3.10.450.710 25 205 4.6E-46 T 13-10-2018 MADE_1004235 cc4433f88ddc215e31232bfa14bee229 221 Pfam PF05494 MlaC protein 34 199 4.4E-50 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC MADE_1020315 bd18ec105a02169eed1a68f43c77941f 123 SMART SM00530 60 114 0.0068 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1020315 bd18ec105a02169eed1a68f43c77941f 123 SUPERFAMILY SSF47413 48 115 8.44E-7 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1020315 bd18ec105a02169eed1a68f43c77941f 123 Gene3D G3DSA:1.10.260.40 52 117 2.7E-7 T 13-10-2018 MADE_1008875 9690ddba66bf28a9e5d0c87f44600c0f 153 Pfam PF01575 MaoC like domain 14 123 2.9E-23 T 13-10-2018 IPR002539 MaoC-like dehydratase domain MADE_1008875 9690ddba66bf28a9e5d0c87f44600c0f 153 SUPERFAMILY SSF54637 10 150 2.4E-31 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1008875 9690ddba66bf28a9e5d0c87f44600c0f 153 Gene3D G3DSA:3.10.129.10 5 150 8.5E-34 T 13-10-2018 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 269 42.76 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 SUPERFAMILY SSF46946 130 221 9.42E-29 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 Gene3D G3DSA:3.20.190.10 2 126 6.8E-41 T 13-10-2018 IPR035937 MutM-like, N-terminal MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 SUPERFAMILY SSF57716 217 268 2.22E-16 T 13-10-2018 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 244 268 - T 13-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.6E-33 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 SUPERFAMILY SSF81624 2 138 5.49E-40 T 13-10-2018 IPR035937 MutM-like, N-terminal MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 2.0E-92 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 SMART SM01232 129 221 3.2E-45 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 129 218 1.7E-24 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 SMART SM00898 2 115 5.8E-53 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 Gene3D G3DSA:1.10.8.50 131 269 4.9E-47 T 13-10-2018 MADE_1000280 cb2c83a9b4278172439a2a8c5c6cfe26 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 268 4.0E-10 T 13-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MADE_1014135 12954d40cf8be388522e28285f39767f 679 Gene3D G3DSA:2.170.130.10 91 179 1.5E-16 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1014135 12954d40cf8be388522e28285f39767f 679 Pfam PF00593 TonB dependent receptor 226 674 4.6E-18 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1014135 12954d40cf8be388522e28285f39767f 679 Gene3D G3DSA:2.40.170.20 180 677 9.9E-44 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1014135 12954d40cf8be388522e28285f39767f 679 SUPERFAMILY SSF56935 51 663 3.14E-55 T 13-10-2018 MADE_1014135 12954d40cf8be388522e28285f39767f 679 Pfam PF07715 TonB-dependent Receptor Plug Domain 96 177 4.5E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 SUPERFAMILY SSF55681 4 246 2.16E-110 T 13-10-2018 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 SUPERFAMILY SSF101353 247 454 3.4E-61 T 13-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Pfam PF01411 tRNA synthetases class II (A) 8 544 8.5E-231 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 643 686 7.8E-20 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 PRINTS PR00980 Alanyl-tRNA synthetase signature 76 87 1.4E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 PRINTS PR00980 Alanyl-tRNA synthetase signature 227 240 1.4E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 PRINTS PR00980 Alanyl-tRNA synthetase signature 273 289 1.4E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 PRINTS PR00980 Alanyl-tRNA synthetase signature 200 211 1.4E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 PRINTS PR00980 Alanyl-tRNA synthetase signature 297 310 1.4E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 SUPERFAMILY SSF55186 542 701 4.45E-53 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Pfam PF02272 DHHA1 domain 723 860 1.1E-29 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Gene3D G3DSA:3.30.930.10 2 243 1.4E-117 T 13-10-2018 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Gene3D G3DSA:3.30.54.20 614 667 3.4E-52 T 13-10-2018 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 865 200.345 T 13-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 SUPERFAMILY SSF50447 446 542 6.36E-17 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Gene3D G3DSA:3.30.980.10 552 687 3.4E-52 T 13-10-2018 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Gene3D G3DSA:2.40.30.130 452 542 1.8E-12 T 13-10-2018 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 SMART SM00863 643 686 3.8E-24 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 Gene3D G3DSA:3.10.310.40 754 862 2.0E-32 T 13-10-2018 MADE_1006100 fb234ca0477113668c349e96f3fa59b0 865 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 844 0.0 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 Pfam PF00890 FAD binding domain 9 405 2.3E-119 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 SUPERFAMILY SSF51905 4 437 4.13E-75 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 PIRSF PIRSF000171 1 582 1.5E-48 T 13-10-2018 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 Gene3D G3DSA:4.10.80.40 550 590 1.9E-22 T 13-10-2018 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 6 590 2.4E-273 T 13-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 Gene3D G3DSA:3.90.700.10 246 350 5.8E-171 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 SUPERFAMILY SSF56425 236 356 1.79E-42 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 Pfam PF02910 Fumarate reductase flavoprotein C-term 463 590 1.6E-34 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 590 2.0E-239 T 13-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 Gene3D G3DSA:3.50.50.60 9 416 5.8E-171 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 13-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 Gene3D G3DSA:1.20.58.100 431 549 6.9E-38 T 13-10-2018 MADE_1009485 f6a190cb40a6f1f3f0dd7854753ec566 590 SUPERFAMILY SSF46977 454 590 1.26E-44 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 MADE_1000575 13be395224f3abbc888a6838b12327a4 737 SMART SM00487 274 464 3.4E-18 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1000575 13be395224f3abbc888a6838b12327a4 737 Pfam PF00271 Helicase conserved C-terminal domain 537 659 7.2E-10 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1000575 13be395224f3abbc888a6838b12327a4 737 Pfam PF04851 Type III restriction enzyme, res subunit 277 441 3.5E-22 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MADE_1000575 13be395224f3abbc888a6838b12327a4 737 SUPERFAMILY SSF52540 295 663 5.5E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000575 13be395224f3abbc888a6838b12327a4 737 SMART SM00490 576 660 9.1E-9 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1000575 13be395224f3abbc888a6838b12327a4 737 Gene3D G3DSA:3.40.50.300 267 460 3.5E-29 T 13-10-2018 MADE_1000575 13be395224f3abbc888a6838b12327a4 737 Gene3D G3DSA:3.40.50.300 465 680 1.5E-33 T 13-10-2018 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 SUPERFAMILY SSF53187 192 506 2.2E-122 T 13-10-2018 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 PRINTS PR00481 Cytosol aminopeptidase signature 334 355 3.0E-54 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 PRINTS PR00481 Cytosol aminopeptidase signature 356 376 3.0E-54 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 PRINTS PR00481 Cytosol aminopeptidase signature 297 318 3.0E-54 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 PRINTS PR00481 Cytosol aminopeptidase signature 384 399 3.0E-54 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 PRINTS PR00481 Cytosol aminopeptidase signature 275 292 3.0E-54 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 Gene3D G3DSA:3.40.630.10 193 508 1.1E-136 T 13-10-2018 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 15 508 39.794 T 13-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 SUPERFAMILY SSF52949 14 195 1.35E-49 T 13-10-2018 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 Gene3D G3DSA:3.40.220.10 13 171 2.5E-57 T 13-10-2018 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 31 159 3.7E-33 T 13-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 198 499 6.6E-123 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MADE_1016060 2263d624b98e7b707b574ba1e0f44d76 513 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 360 367 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 15 608 3.3E-254 T 13-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 SUPERFAMILY SSF63380 238 455 2.89E-62 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 Pfam PF00258 Flavodoxin 73 200 3.5E-32 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 Pfam PF00175 Oxidoreductase NAD-binding domain 466 572 3.5E-18 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 SUPERFAMILY SSF52218 70 217 2.1E-47 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 Gene3D G3DSA:3.40.50.80 454 608 8.3E-59 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 Gene3D G3DSA:2.40.30.10 241 448 7.4E-71 T 13-10-2018 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 SUPERFAMILY SSF52343 453 608 2.62E-51 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PIRSF PIRSF000207 1 608 3.1E-256 T 13-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 Pfam PF00667 FAD binding domain 241 433 2.6E-24 T 13-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 Gene3D G3DSA:3.40.50.360 63 225 1.3E-49 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00369 Flavodoxin signature 152 162 3.4E-13 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00369 Flavodoxin signature 176 195 3.4E-13 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00369 Flavodoxin signature 72 85 3.4E-13 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00369 Flavodoxin signature 120 131 3.4E-13 T 13-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 465 484 3.5E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 395 402 3.5E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 279 289 3.5E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 490 499 3.5E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 503 514 3.5E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 534 550 3.5E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 557 565 3.5E-25 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1016740 16d1d29635b281428e5fa452caf745d0 608 Gene3D G3DSA:1.20.990.10 289 393 7.4E-71 T 13-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 MADE_1000410 f7e3352c100ed003cf159c82f10940f7 150 SUPERFAMILY SSF46785 2 134 1.06E-32 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1000410 f7e3352c100ed003cf159c82f10940f7 150 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 1.9E-29 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type MADE_1000410 f7e3352c100ed003cf159c82f10940f7 150 Pfam PF02082 Transcriptional regulator 1 81 2.5E-19 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type MADE_1000410 f7e3352c100ed003cf159c82f10940f7 150 Gene3D G3DSA:1.10.10.10 1 143 3.4E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009260 13596a4a509fbe6bdf5ef4d19bf33e35 366 SUPERFAMILY SSF56601 42 334 2.63E-60 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1009260 13596a4a509fbe6bdf5ef4d19bf33e35 366 Gene3D G3DSA:3.40.710.10 40 345 1.0E-63 T 13-10-2018 MADE_1009260 13596a4a509fbe6bdf5ef4d19bf33e35 366 Pfam PF00144 Beta-lactamase 55 280 6.0E-47 T 13-10-2018 IPR001466 Beta-lactamase-related MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 PIRSF PIRSF039144 1 112 5.1E-55 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 Gene3D G3DSA:3.30.70.120 1 112 8.8E-47 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 PRINTS PR00340 P-II protein signature 23 41 3.8E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 PRINTS PR00340 P-II protein signature 2 17 3.8E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 PRINTS PR00340 P-II protein signature 83 103 3.8E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 PRINTS PR00340 P-II protein signature 52 75 3.8E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 SMART SM00938 4 105 5.9E-66 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.2E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 MADE_1002420 7941d919c1085f14ddf1ffa16bf6baff 112 SUPERFAMILY SSF54913 1 112 5.72E-45 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 Gene3D G3DSA:3.30.420.40 127 255 1.2E-22 T 13-10-2018 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 SUPERFAMILY SSF53067 3 252 3.89E-22 T 13-10-2018 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 Gene3D G3DSA:3.30.420.40 435 482 4.3E-10 T 13-10-2018 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 Gene3D G3DSA:3.90.640.10 301 312 1.2E-22 T 13-10-2018 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 Gene3D G3DSA:3.30.420.40 483 494 4.3E-10 T 13-10-2018 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 Gene3D G3DSA:3.90.640.10 375 434 4.3E-10 T 13-10-2018 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 Pfam PF00012 Hsp70 protein 179 310 2.2E-9 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 Gene3D G3DSA:3.30.420.40 256 300 1.2E-22 T 13-10-2018 MADE_1001085 32b889def80ee34414cf2fbb93f09a24 500 SUPERFAMILY SSF53067 258 497 1.37E-25 T 13-10-2018 MADE_1020495 ceb1c54007433bfe8229b58f4a6e6363 292 Gene3D G3DSA:3.90.1530.30 53 116 6.4E-28 T 13-10-2018 MADE_1020495 ceb1c54007433bfe8229b58f4a6e6363 292 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 37 211 8.7E-60 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 MADE_1020495 ceb1c54007433bfe8229b58f4a6e6363 292 SMART SM00470 40 130 5.8E-38 T 13-10-2018 IPR003115 ParB/Sulfiredoxin MADE_1020495 ceb1c54007433bfe8229b58f4a6e6363 292 Pfam PF02195 ParB-like nuclease domain 42 130 2.4E-30 T 13-10-2018 IPR003115 ParB/Sulfiredoxin MADE_1020495 ceb1c54007433bfe8229b58f4a6e6363 292 SUPERFAMILY SSF110849 39 175 5.75E-36 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily MADE_1020495 ceb1c54007433bfe8229b58f4a6e6363 292 Gene3D G3DSA:1.10.10.2830 117 230 2.2E-35 T 13-10-2018 MADE_1004515 ddc7ff1e9faf48719acfb2b78fa50af6 170 Pfam PF05981 CreA protein 40 162 1.7E-45 T 13-10-2018 IPR010292 Uncharacterised protein family CreA MADE_1004515 ddc7ff1e9faf48719acfb2b78fa50af6 170 PIRSF PIRSF003174 12 170 1.4E-48 T 13-10-2018 IPR010292 Uncharacterised protein family CreA MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 Gene3D G3DSA:3.40.50.2300 122 251 1.7E-11 T 13-10-2018 MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 Gene3D G3DSA:3.30.70.270 252 415 3.7E-46 T 13-10-2018 MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 Pfam PF00072 Response regulator receiver domain 129 232 4.3E-9 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 Gene3D G3DSA:3.40.50.2300 1 121 4.2E-6 T 13-10-2018 MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 SUPERFAMILY SSF52172 128 259 1.85E-14 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 SMART SM00448 127 241 2.9E-4 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 SUPERFAMILY SSF55073 263 411 7.85E-38 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 256 412 1.5E-39 T 13-10-2018 IPR000160 GGDEF domain MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 SMART SM00267 247 413 7.6E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 Pfam PF00990 Diguanylate cyclase, GGDEF domain 258 409 3.6E-35 T 13-10-2018 IPR000160 GGDEF domain MADE_1000980 0421d83786bb6e92ca12d59a2bb34c3d 426 SUPERFAMILY SSF52172 4 118 7.54E-7 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1019395 74aae3eb69a1d9b92fb2fab1c9240fe0 229 Gene3D G3DSA:1.20.120.520 78 213 5.5E-27 T 13-10-2018 MADE_1019395 74aae3eb69a1d9b92fb2fab1c9240fe0 229 Pfam PF01814 Hemerythrin HHE cation binding domain 76 211 1.3E-21 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MADE_1019395 74aae3eb69a1d9b92fb2fab1c9240fe0 229 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 7 211 1.1E-70 T 13-10-2018 IPR019903 Repair of iron centres family MADE_1019395 74aae3eb69a1d9b92fb2fab1c9240fe0 229 Pfam PF04405 Domain of Unknown function (DUF542) 4 58 2.9E-20 T 13-10-2018 IPR019903 Repair of iron centres family MADE_1009975 8e231342c9cce863daed12f6690b7dec 329 Gene3D G3DSA:3.40.50.720 129 297 7.1E-118 T 13-10-2018 MADE_1009975 8e231342c9cce863daed12f6690b7dec 329 Gene3D G3DSA:3.90.180.10 21 328 7.1E-118 T 13-10-2018 MADE_1009975 8e231342c9cce863daed12f6690b7dec 329 Pfam PF00107 Zinc-binding dehydrogenase 162 271 2.0E-15 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1009975 8e231342c9cce863daed12f6690b7dec 329 SUPERFAMILY SSF51735 119 296 3.18E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009975 8e231342c9cce863daed12f6690b7dec 329 SUPERFAMILY SSF50129 12 149 2.04E-38 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1009975 8e231342c9cce863daed12f6690b7dec 329 SMART SM00829 12 327 2.7E-5 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1009975 8e231342c9cce863daed12f6690b7dec 329 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 5 329 1.2E-137 T 13-10-2018 IPR014188 Acrylyl-CoA reductase AcuI MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 SMART SM00448 2 115 1.1E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 Pfam PF00072 Response regulator receiver domain 4 115 1.2E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 SMART SM00421 146 203 1.7E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 Gene3D G3DSA:3.40.50.12740 2 209 8.6E-59 T 13-10-2018 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 SUPERFAMILY SSF46894 142 211 4.76E-18 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.1E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 4.9E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 4.9E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 4.9E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001022075 b64737daa8f7a0b89c5e265f259cacdf 214 SUPERFAMILY SSF52172 2 131 2.28E-32 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1008230 802c72a2eb146fbac71d94b6791977db 248 SUPERFAMILY SSF53448 9 218 1.41E-39 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008230 802c72a2eb146fbac71d94b6791977db 248 Pfam PF00535 Glycosyl transferase family 2 10 160 8.2E-26 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1008230 802c72a2eb146fbac71d94b6791977db 248 Gene3D G3DSA:3.90.550.10 1 245 1.2E-43 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1006825 e66f7fd41d26c0042103350707022ca9 232 SMART SM00382 30 216 2.2E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1006825 e66f7fd41d26c0042103350707022ca9 232 Pfam PF00005 ABC transporter 21 167 2.4E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1006825 e66f7fd41d26c0042103350707022ca9 232 Gene3D G3DSA:3.40.50.300 1 231 7.4E-67 T 13-10-2018 MADE_1006825 e66f7fd41d26c0042103350707022ca9 232 SUPERFAMILY SSF52540 1 223 6.05E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006825 e66f7fd41d26c0042103350707022ca9 232 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1009665 e52088bb075d9f221919b4006f89342e 71 Pfam PF13242 HAD-hyrolase-like 1 66 2.1E-7 T 13-10-2018 MADE_1009665 e52088bb075d9f221919b4006f89342e 71 SUPERFAMILY SSF56784 1 68 1.91E-10 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1009665 e52088bb075d9f221919b4006f89342e 71 Gene3D G3DSA:3.40.50.1000 1 70 2.2E-11 T 13-10-2018 IPR023214 HAD superfamily MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 Gene3D G3DSA:3.40.50.2300 61 324 3.2E-44 T 13-10-2018 MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 Pfam PF13377 Periplasmic binding protein-like domain 204 331 5.0E-23 T 13-10-2018 MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 SUPERFAMILY SSF47413 5 64 1.44E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 50 1.8E-8 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 SUPERFAMILY SSF53822 64 329 9.97E-37 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 SMART SM00354 5 76 1.3E-11 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 Gene3D G3DSA:1.10.260.40 1 60 3.4E-16 T 13-10-2018 MADE_000001022375 a78e58c32455dd78be1320493cce215e 341 Gene3D G3DSA:3.40.50.2300 161 307 3.2E-44 T 13-10-2018 MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 13-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 SMART SM01403 7 101 3.8E-57 T 13-10-2018 IPR027486 Ribosomal protein S10 domain MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 SUPERFAMILY SSF54999 5 101 5.89E-37 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 Gene3D G3DSA:3.30.70.600 1 103 5.6E-38 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.2E-35 T 13-10-2018 IPR027486 Ribosomal protein S10 domain MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 9.5E-47 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.185 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 8.3E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 8.3E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002255 606e6d2095dfb9e5b5cda28463815b76 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 8.3E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 SUPERFAMILY SSF52172 2 107 5.83E-25 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 340 39.861 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 SMART SM00448 3 116 3.2E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 Gene3D G3DSA:3.40.50.2300 1 132 3.2E-26 T 13-10-2018 MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 SUPERFAMILY SSF52738 152 340 9.42E-69 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 PIRSF PIRSF000876 1 344 7.4E-131 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 Pfam PF00072 Response regulator receiver domain 5 107 2.3E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 Gene3D G3DSA:3.40.50.180 146 344 3.7E-74 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal MADE_1002020 15d30a3ebb3181502928d51900a45f21 348 Pfam PF01339 CheB methylesterase 157 334 5.1E-58 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 Pfam PF00664 ABC transporter transmembrane region 177 442 1.1E-31 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 SUPERFAMILY SSF90123 164 465 1.31E-51 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 ProSitePatterns PS00211 ABC transporters family signature. 630 644 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 SUPERFAMILY SSF52540 496 704 5.14E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 Gene3D G3DSA:1.20.1560.10 161 474 1.1E-59 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 Gene3D G3DSA:3.90.70.10 10 154 4.0E-41 T 13-10-2018 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 SMART SM00382 527 702 2.3E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 Pfam PF03412 Peptidase C39 family 20 148 1.3E-34 T 13-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 Gene3D G3DSA:3.40.50.300 476 714 7.9E-62 T 13-10-2018 MADE_1018255 84e66dfd1594faeab4f4494fd4cbdf57 724 Pfam PF00005 ABC transporter 519 657 5.8E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Gene3D G3DSA:2.40.50.100 124 157 2.0E-6 T 13-10-2018 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Gene3D G3DSA:2.40.30.170 158 202 2.0E-6 T 13-10-2018 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Gene3D G3DSA:2.40.30.170 72 85 7.5E-10 T 13-10-2018 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Gene3D G3DSA:2.40.420.20 235 310 5.9E-14 T 13-10-2018 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Gene3D G3DSA:2.40.50.100 86 119 7.5E-10 T 13-10-2018 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Gene3D G3DSA:2.40.420.20 61 71 7.5E-10 T 13-10-2018 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 SUPERFAMILY SSF51230 79 150 1.96E-11 T 13-10-2018 IPR011053 Single hybrid motif MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Pfam PF13437 HlyD family secretion protein 128 206 1.2E-6 T 13-10-2018 MADE_1010270 ce9761184e875630c8f249fe740cac96 311 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 69 123 9.6E-9 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1015685 5f0d9099313f479accebb2d692f078a0 754 Gene3D G3DSA:2.40.170.20 53 754 1.8E-114 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1015685 5f0d9099313f479accebb2d692f078a0 754 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 170 4.8E-17 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1015685 5f0d9099313f479accebb2d692f078a0 754 SUPERFAMILY SSF56935 38 733 3.36E-101 T 13-10-2018 MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 Pfam PF16657 Maltogenic Amylase, C-terminal domain 359 429 1.3E-6 T 13-10-2018 IPR032091 Maltogenic Amylase, C-terminal MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 Gene3D G3DSA:2.60.40.1180 363 432 7.4E-8 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 Pfam PF00128 Alpha amylase, catalytic domain 36 130 1.9E-18 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 Pfam PF00128 Alpha amylase, catalytic domain 155 313 9.6E-12 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 SMART SM00642 26 343 1.8E-16 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 SUPERFAMILY SSF51445 11 351 5.86E-78 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 Gene3D G3DSA:3.20.20.80 12 349 3.5E-101 T 13-10-2018 MADE_1012260 a5a8765e70ffa6d0c11d12d94b216e28 434 SUPERFAMILY SSF51011 367 433 2.08E-9 T 13-10-2018 MADE_1014395 4344074d8f320ffadb54098e0d5225f0 231 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 1 34 3.9E-7 T 13-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal MADE_1014395 4344074d8f320ffadb54098e0d5225f0 231 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 1 222 1.4E-45 T 13-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 MADE_1014395 4344074d8f320ffadb54098e0d5225f0 231 Gene3D G3DSA:3.30.70.2660 1 227 1.2E-52 T 13-10-2018 MADE_1014395 4344074d8f320ffadb54098e0d5225f0 231 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 1 223 1.1E-47 T 13-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 MADE_000001021650 491c3f72e9d0ff538ae0f16e605a18c2 168 SUPERFAMILY SSF47741 72 153 9.29E-31 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MADE_000001021650 491c3f72e9d0ff538ae0f16e605a18c2 168 Gene3D G3DSA:1.10.150.120 74 165 2.1E-26 T 13-10-2018 MADE_000001021650 491c3f72e9d0ff538ae0f16e605a18c2 168 SUPERFAMILY SSF54292 2 77 1.27E-25 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_000001021650 491c3f72e9d0ff538ae0f16e605a18c2 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 54 1.5E-6 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MADE_000001021650 491c3f72e9d0ff538ae0f16e605a18c2 168 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MADE_000001021650 491c3f72e9d0ff538ae0f16e605a18c2 168 Pfam PF01799 [2Fe-2S] binding domain 72 144 1.4E-28 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MADE_000001021650 491c3f72e9d0ff538ae0f16e605a18c2 168 Gene3D G3DSA:3.10.20.30 1 73 3.7E-29 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1006430 d2148cf0cf14c2c803afd0914d58e5c4 292 Pfam PF04224 Protein of unknown function, DUF417 142 269 4.2E-18 T 13-10-2018 IPR007339 Inner membrane protein RclC-like MADE_1005500 dd5d7bbf435f9cc003c7cc58a244af38 145 Gene3D G3DSA:1.10.1660.10 34 145 4.5E-14 T 13-10-2018 MADE_1005500 dd5d7bbf435f9cc003c7cc58a244af38 145 Pfam PF13411 MerR HTH family regulatory protein 39 104 4.3E-8 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005500 dd5d7bbf435f9cc003c7cc58a244af38 145 SUPERFAMILY SSF46955 38 139 1.39E-13 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1005500 dd5d7bbf435f9cc003c7cc58a244af38 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 50 63 1.7E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005500 dd5d7bbf435f9cc003c7cc58a244af38 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 74 94 1.7E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005500 dd5d7bbf435f9cc003c7cc58a244af38 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 50 1.7E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005500 dd5d7bbf435f9cc003c7cc58a244af38 145 SMART SM00422 38 107 1.7E-5 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 61 205 1.6E-30 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 Gene3D G3DSA:4.10.480.10 225 312 4.3E-38 T 13-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 Gene3D G3DSA:3.40.50.700 45 224 6.4E-64 T 13-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 15 38 4.6E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 SUPERFAMILY SSF56770 47 308 8.77E-85 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PIRSF PIRSF000310 4 328 1.9E-128 T 13-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 212 229 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 186 209 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 69 93 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 254 280 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 46 68 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 115 138 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 157 181 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 282 295 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 230 248 5.2E-73 T 13-10-2018 MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 225 307 4.0E-32 T 13-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal MADE_1001670 490dcc5d45a7ea24e7cf2e8563ec29f7 332 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 5 328 2.7E-126 T 13-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 MADE_1020050 ebc5378fb929b6340af606e35b8e2dac 400 SUPERFAMILY SSF88713 90 309 1.21E-33 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MADE_1020050 ebc5378fb929b6340af606e35b8e2dac 400 Pfam PF01522 Polysaccharide deacetylase 127 258 1.4E-20 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MADE_1020050 ebc5378fb929b6340af606e35b8e2dac 400 Gene3D G3DSA:3.20.20.370 71 293 3.1E-53 T 13-10-2018 MADE_1010805 8b7061cc201371f4ad904066c81614e1 291 Pfam PF00892 EamA-like transporter family 159 289 2.1E-15 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1010805 8b7061cc201371f4ad904066c81614e1 291 Pfam PF00892 EamA-like transporter family 3 145 1.8E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1010805 8b7061cc201371f4ad904066c81614e1 291 SUPERFAMILY SSF103481 201 289 9.42E-12 T 13-10-2018 MADE_1010805 8b7061cc201371f4ad904066c81614e1 291 SUPERFAMILY SSF103481 74 149 1.7E-6 T 13-10-2018 MADE_1003000 f8cf0173dbf59d9fc62235401770702a 135 Gene3D G3DSA:3.10.180.10 8 135 3.7E-27 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1003000 f8cf0173dbf59d9fc62235401770702a 135 SUPERFAMILY SSF54593 7 134 2.69E-18 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1003000 f8cf0173dbf59d9fc62235401770702a 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 130 1.0E-10 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_1016975 0df610e76fbac838eb825c00ca235902 270 SUPERFAMILY SSF51735 14 260 2.2E-21 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1016975 0df610e76fbac838eb825c00ca235902 270 Pfam PF01370 NAD dependent epimerase/dehydratase family 86 187 5.0E-10 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MADE_1016975 0df610e76fbac838eb825c00ca235902 270 Gene3D G3DSA:3.40.50.720 1 268 2.6E-45 T 13-10-2018 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 Pfam PF05649 Peptidase family M13 55 432 9.1E-102 T 13-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 Gene3D G3DSA:3.40.390.10 50 688 5.3E-244 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 Gene3D G3DSA:1.10.1380.10 81 471 5.3E-244 T 13-10-2018 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 476 488 1.9E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 515 531 1.9E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 586 597 1.9E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 494 506 1.9E-22 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 Pfam PF01431 Peptidase family M13 484 685 7.3E-74 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_000001023365 f2a8719bd785f65ae511a2576191656c 688 SUPERFAMILY SSF55486 40 688 6.1E-215 T 13-10-2018 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 8.9E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 8.9E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 8.9E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 8.9E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 8.9E-55 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Gene3D G3DSA:3.30.980.10 69 222 3.9E-64 T 13-10-2018 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 SUPERFAMILY SSF55681 243 525 1.17E-98 T 13-10-2018 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 SUPERFAMILY SSF55186 63 241 2.22E-65 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Gene3D G3DSA:3.30.54.20 130 187 3.9E-64 T 13-10-2018 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 SUPERFAMILY SSF81271 3 61 1.7E-15 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Gene3D G3DSA:3.40.50.800 532 638 2.0E-30 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 SMART SM00863 170 219 2.0E-19 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Gene3D G3DSA:3.10.20.30 3 62 4.2E-22 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 319 528 1.0E-47 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Pfam PF03129 Anticodon binding domain 541 630 2.2E-22 T 13-10-2018 IPR004154 Anticodon-binding MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Gene3D G3DSA:3.30.930.10 223 531 1.8E-130 T 13-10-2018 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 SUPERFAMILY SSF52954 530 632 4.38E-31 T 13-10-2018 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 219 9.1E-14 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Pfam PF02824 TGS domain 4 61 8.3E-11 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 631 1.9E-243 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MADE_1008080 fe3a70d62b0ada99d4fb28317ae42cb8 638 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 634 34.412 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 Gene3D G3DSA:2.70.150.20 222 334 3.2E-42 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 162 739 1.9E-188 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 Pfam PF00403 Heavy-metal-associated domain 12 66 3.8E-12 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 SUPERFAMILY SSF81653 233 329 9.15E-30 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 566 5.3E-28 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 279 293 5.3E-28 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 665 5.3E-28 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 577 587 5.3E-28 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 630 649 5.3E-28 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 431 445 5.3E-28 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 Gene3D G3DSA:3.40.1110.10 442 562 4.4E-94 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 Pfam PF00122 E1-E2 ATPase 230 410 1.6E-55 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 SUPERFAMILY SSF55008 4 73 2.62E-16 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 Gene3D G3DSA:3.30.70.100 8 70 1.7E-15 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 SUPERFAMILY SSF56784 431 736 7.66E-54 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 602 618 2.8E-10 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 630 646 2.8E-10 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 661 686 2.8E-10 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 207 707 1.0E-90 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 433 439 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 SUPERFAMILY SSF81665 202 707 6.54E-10 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 Pfam PF00702 haloacid dehalogenase-like hydrolase 428 644 6.7E-41 T 13-10-2018 MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 Gene3D G3DSA:3.40.50.1000 412 682 4.4E-94 T 13-10-2018 IPR023214 HAD superfamily MADE_1001920 2c2db4180ee9e64d1bac497acc698af8 747 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 144 740 1.9E-186 T 13-10-2018 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 Gene3D G3DSA:3.30.1130.10 149 286 9.1E-58 T 13-10-2018 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 Pfam PF14489 QueF-like protein 200 275 3.0E-27 T 13-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 TIGRFAM TIGR03138 QueF: queuine synthase 16 286 1.1E-123 T 13-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 Gene3D G3DSA:3.30.1130.10 26 144 1.3E-42 T 13-10-2018 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 286 148.093 T 13-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 26 136 5.1E-47 T 13-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 PIRSF PIRSF004750 12 286 2.1E-122 T 13-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 MADE_1004900 5e855cbedf74726c6b77ce88a3478e60 286 SUPERFAMILY SSF55620 188 270 4.52E-9 T 13-10-2018 MADE_1006295 34d523e17a80031a7b86cb0ef3f649ff 696 SUPERFAMILY SSF56935 32 696 2.62E-82 T 13-10-2018 MADE_1006295 34d523e17a80031a7b86cb0ef3f649ff 696 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 679 696 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site MADE_1006295 34d523e17a80031a7b86cb0ef3f649ff 696 Pfam PF07715 TonB-dependent Receptor Plug Domain 51 156 1.7E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1006295 34d523e17a80031a7b86cb0ef3f649ff 696 Pfam PF00593 TonB dependent receptor 238 695 2.0E-27 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1006295 34d523e17a80031a7b86cb0ef3f649ff 696 Gene3D G3DSA:2.40.170.20 44 696 2.8E-103 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1010040 b5056f506ca953e92e304adec6880176 554 SUPERFAMILY SSF54106 366 411 1.44E-11 T 13-10-2018 MADE_1010040 b5056f506ca953e92e304adec6880176 554 Pfam PF01464 Transglycosylase SLT domain 146 245 6.5E-23 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 MADE_1010040 b5056f506ca953e92e304adec6880176 554 Gene3D G3DSA:1.10.530.10 132 287 1.2E-31 T 13-10-2018 MADE_1010040 b5056f506ca953e92e304adec6880176 554 SUPERFAMILY SSF53955 136 285 2.06E-43 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1010040 b5056f506ca953e92e304adec6880176 554 SMART SM00257 368 411 1.4E-15 T 13-10-2018 IPR018392 LysM domain MADE_1010040 b5056f506ca953e92e304adec6880176 554 SMART SM00257 442 486 7.6E-17 T 13-10-2018 IPR018392 LysM domain MADE_1010040 b5056f506ca953e92e304adec6880176 554 SMART SM00257 500 544 2.9E-12 T 13-10-2018 IPR018392 LysM domain MADE_1010040 b5056f506ca953e92e304adec6880176 554 SUPERFAMILY SSF54106 499 544 1.7E-10 T 13-10-2018 MADE_1010040 b5056f506ca953e92e304adec6880176 554 SUPERFAMILY SSF54106 441 486 9.29E-13 T 13-10-2018 MADE_1010040 b5056f506ca953e92e304adec6880176 554 Pfam PF01476 LysM domain 501 543 1.2E-12 T 13-10-2018 IPR018392 LysM domain MADE_1010040 b5056f506ca953e92e304adec6880176 554 Pfam PF01476 LysM domain 443 486 8.9E-16 T 13-10-2018 IPR018392 LysM domain MADE_1010040 b5056f506ca953e92e304adec6880176 554 Pfam PF01476 LysM domain 369 411 3.7E-13 T 13-10-2018 IPR018392 LysM domain MADE_1010040 b5056f506ca953e92e304adec6880176 554 Gene3D G3DSA:3.10.350.10 429 496 5.6E-18 T 13-10-2018 IPR036779 LysM domain superfamily MADE_1010040 b5056f506ca953e92e304adec6880176 554 Gene3D G3DSA:3.10.350.10 356 418 4.1E-16 T 13-10-2018 IPR036779 LysM domain superfamily MADE_1010040 b5056f506ca953e92e304adec6880176 554 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 157 185 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 MADE_1010040 b5056f506ca953e92e304adec6880176 554 Gene3D G3DSA:3.10.350.10 498 546 4.6E-15 T 13-10-2018 IPR036779 LysM domain superfamily MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 ProSitePatterns PS00460 Glutathione peroxidases active site. 50 65 - T 13-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 Pfam PF00255 Glutathione peroxidase 32 136 1.9E-26 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 SUPERFAMILY SSF52833 36 182 3.06E-42 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 PRINTS PR01011 Glutathione peroxidase family signature 48 65 1.0E-11 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 PRINTS PR01011 Glutathione peroxidase family signature 143 152 1.0E-11 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 PRINTS PR01011 Glutathione peroxidase family signature 83 99 1.0E-11 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 Gene3D G3DSA:3.40.30.10 18 184 6.5E-47 T 13-10-2018 MADE_1007335 31de9ce656169e1e1ffbd232a1adce09 184 PIRSF PIRSF000303 1 184 4.9E-55 T 13-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 MADE_1016670 fecc664214690a243b1d8f754b7e1e0e 192 Gene3D G3DSA:1.10.238.10 125 191 2.0E-9 T 13-10-2018 MADE_1016670 fecc664214690a243b1d8f754b7e1e0e 192 SUPERFAMILY SSF47473 29 189 2.16E-14 T 13-10-2018 IPR011992 EF-hand domain pair MADE_1016670 fecc664214690a243b1d8f754b7e1e0e 192 Gene3D G3DSA:1.10.238.10 9 106 5.0E-8 T 13-10-2018 MADE_1016670 fecc664214690a243b1d8f754b7e1e0e 192 Pfam PF13202 EF hand 141 157 0.0015 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 Gene3D G3DSA:3.50.7.10 192 372 1.2E-241 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 13-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 Gene3D G3DSA:1.10.560.10 8 521 1.2E-241 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 Gene3D G3DSA:3.30.260.10 136 410 1.2E-241 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 PRINTS PR00298 60kDa chaperonin signature 398 419 1.6E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 PRINTS PR00298 60kDa chaperonin signature 83 110 1.6E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 PRINTS PR00298 60kDa chaperonin signature 27 53 1.6E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 PRINTS PR00298 60kDa chaperonin signature 350 375 1.6E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 PRINTS PR00298 60kDa chaperonin signature 268 291 1.6E-74 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 SUPERFAMILY SSF54849 138 203 9.84E-24 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 6.9E-257 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 8.4E-97 T 13-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 SUPERFAMILY SSF52029 185 376 1.45E-85 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 SUPERFAMILY SSF48592 7 521 4.91E-78 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily MADE_1019625 d1b04ebc832c95f49b7544537f3cff1d 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.787 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 MADE_1008480 6b877c4fea5d96f41faace31929738ec 521 PIRSF PIRSF000977 44 521 1.1E-185 T 13-10-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 MADE_1008480 6b877c4fea5d96f41faace31929738ec 521 Pfam PF00929 Exonuclease 52 233 1.8E-23 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1008480 6b877c4fea5d96f41faace31929738ec 521 Gene3D G3DSA:3.30.420.10 45 241 1.1E-68 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1008480 6b877c4fea5d96f41faace31929738ec 521 SUPERFAMILY SSF53098 50 521 1.3E-125 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1008480 6b877c4fea5d96f41faace31929738ec 521 Gene3D G3DSA:2.30.30.450 254 394 4.0E-44 T 13-10-2018 IPR038649 Exonuclease I, SH3-like domain superfamily MADE_1008480 6b877c4fea5d96f41faace31929738ec 521 Gene3D G3DSA:1.20.1280.70 401 461 2.3E-16 T 13-10-2018 MADE_1008480 6b877c4fea5d96f41faace31929738ec 521 Pfam PF08411 Exonuclease C-terminal 252 519 5.5E-90 T 13-10-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 SUPERFAMILY SSF55035 114 228 7.85E-37 T 13-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 Gene3D G3DSA:3.90.770.10 59 372 1.7E-110 T 13-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 48 69 6.9E-37 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 168 186 6.9E-37 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 311 332 6.9E-37 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 259 285 6.9E-37 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 79 99 6.9E-37 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 209 234 6.9E-37 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 Gene3D G3DSA:3.30.70.420 113 228 1.7E-110 T 13-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 18 386 3.1E-120 T 13-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1004060 e2a9e477c11dd65d401b713ab5b52880 388 SUPERFAMILY SSF56542 13 375 5.49E-70 T 13-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 MADE_1012010 6657b819d0687e105d1c5d044d2c7777 195 Gene3D G3DSA:3.90.180.10 151 176 5.2E-54 T 13-10-2018 MADE_1012010 6657b819d0687e105d1c5d044d2c7777 195 Gene3D G3DSA:3.40.50.720 2 150 5.2E-54 T 13-10-2018 MADE_1012010 6657b819d0687e105d1c5d044d2c7777 195 SMART SM00829 1 177 0.001 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1012010 6657b819d0687e105d1c5d044d2c7777 195 SUPERFAMILY SSF51735 2 155 3.56E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1012010 6657b819d0687e105d1c5d044d2c7777 195 Pfam PF00107 Zinc-binding dehydrogenase 21 137 3.2E-20 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1012010 6657b819d0687e105d1c5d044d2c7777 195 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 10 31 - T 13-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 MADE_1006170 2b2ba3c096e730c689a5ade8844be703 148 Pfam PF04024 PspC domain 5 63 7.6E-19 T 13-10-2018 IPR007168 Phage shock protein, PspC, N-terminal MADE_1006170 2b2ba3c096e730c689a5ade8844be703 148 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 5 148 1.2E-43 T 13-10-2018 IPR014320 Phage shock protein, PspC MADE_1014115 d1d4fe743a7a03ac68d9bcfffa644e3e 165 Gene3D G3DSA:3.10.20.30 1 73 9.2E-30 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1014115 d1d4fe743a7a03ac68d9bcfffa644e3e 165 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MADE_1014115 d1d4fe743a7a03ac68d9bcfffa644e3e 165 Gene3D G3DSA:1.10.150.120 74 165 1.1E-29 T 13-10-2018 MADE_1014115 d1d4fe743a7a03ac68d9bcfffa644e3e 165 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 55 9.6E-9 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MADE_1014115 d1d4fe743a7a03ac68d9bcfffa644e3e 165 Pfam PF01799 [2Fe-2S] binding domain 72 156 1.3E-28 T 13-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 MADE_1014115 d1d4fe743a7a03ac68d9bcfffa644e3e 165 SUPERFAMILY SSF47741 83 162 1.44E-25 T 13-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily MADE_1014115 d1d4fe743a7a03ac68d9bcfffa644e3e 165 SUPERFAMILY SSF54292 3 87 2.62E-26 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_1019605 130fa93edf60fe88e67f3d2b16ab260f 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 10.938 T 13-10-2018 IPR022907 VapC family GO:0004540 MADE_1019605 130fa93edf60fe88e67f3d2b16ab260f 133 SMART SM00670 2 121 6.3E-4 T 13-10-2018 IPR002716 PIN domain MADE_1019605 130fa93edf60fe88e67f3d2b16ab260f 133 Pfam PF01850 PIN domain 4 124 1.3E-15 T 13-10-2018 IPR002716 PIN domain MADE_1019605 130fa93edf60fe88e67f3d2b16ab260f 133 SUPERFAMILY SSF88723 1 131 3.64E-34 T 13-10-2018 IPR029060 PIN-like domain superfamily MADE_1019605 130fa93edf60fe88e67f3d2b16ab260f 133 Gene3D G3DSA:3.40.50.1010 1 132 1.8E-37 T 13-10-2018 MADE_1016240 e58c23edc5de7008f991c5a8e87e0efd 243 Pfam PF10615 Protein of unknown function (DUF2470) 160 228 5.2E-12 T 13-10-2018 IPR019595 Domain of unknown function DUF2470 MADE_1016240 e58c23edc5de7008f991c5a8e87e0efd 243 SUPERFAMILY SSF50475 3 233 1.87E-47 T 13-10-2018 MADE_1016240 e58c23edc5de7008f991c5a8e87e0efd 243 Pfam PF13883 Pyridoxamine 5'-phosphate oxidase 3 147 3.0E-18 T 13-10-2018 MADE_1016240 e58c23edc5de7008f991c5a8e87e0efd 243 Gene3D G3DSA:3.20.180.10 154 241 7.3E-18 T 13-10-2018 IPR037119 Haem oxygenase HugZ-like superfamily MADE_1016240 e58c23edc5de7008f991c5a8e87e0efd 243 Gene3D G3DSA:2.30.110.10 1 145 8.1E-41 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_1006595 7daedc01a014e3809a180f1f9725be75 210 Pfam PF00929 Exonuclease 18 192 7.1E-37 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1006595 7daedc01a014e3809a180f1f9725be75 210 Hamap MF_00157 Ribonuclease T [rnt]. 1 210 107.89 T 13-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MADE_1006595 7daedc01a014e3809a180f1f9725be75 210 SUPERFAMILY SSF53098 7 205 1.11E-57 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1006595 7daedc01a014e3809a180f1f9725be75 210 Gene3D G3DSA:3.30.420.10 7 210 9.2E-55 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1006595 7daedc01a014e3809a180f1f9725be75 210 SMART SM00479 16 201 1.0E-30 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1006595 7daedc01a014e3809a180f1f9725be75 210 TIGRFAM TIGR01298 RNaseT: ribonuclease T 8 206 1.9E-97 T 13-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 Gene3D G3DSA:2.30.30.30 2 104 2.9E-41 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 Pfam PF00467 KOW motif 8 38 6.0E-7 T 13-10-2018 IPR005824 KOW MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 98 21.853 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 102 5.5E-26 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 13-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 2.9E-41 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 SUPERFAMILY SSF50104 4 102 1.12E-36 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily MADE_1014005 eb06e5b79af179be759a1c4f894ff4af 104 SMART SM00739 4 31 1.1E-4 T 13-10-2018 IPR005824 KOW MADE_1015045 1649736fbc3e9086b7035373b05adc3c 290 Gene3D G3DSA:2.20.25.160 217 264 7.0E-102 T 13-10-2018 MADE_1015045 1649736fbc3e9086b7035373b05adc3c 290 Gene3D G3DSA:3.40.630.10 5 287 7.0E-102 T 13-10-2018 MADE_1015045 1649736fbc3e9086b7035373b05adc3c 290 SUPERFAMILY SSF53187 3 287 1.33E-66 T 13-10-2018 MADE_1015045 1649736fbc3e9086b7035373b05adc3c 290 PIRSF PIRSF018001 1 290 7.2E-70 T 13-10-2018 IPR016708 Aspartoacylase GO:0016811 MADE_1015045 1649736fbc3e9086b7035373b05adc3c 290 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 4 282 1.2E-39 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MADE_1015045 1649736fbc3e9086b7035373b05adc3c 290 Hamap MF_00704 Probable aspartoacylase. 1 290 28.535 T 13-10-2018 IPR016708 Aspartoacylase GO:0016811 MADE_1000095 71322c69598f281cd56711b67112ffc1 439 Gene3D G3DSA:1.10.940.10 6 143 5.7E-36 T 13-10-2018 IPR035926 NusB-like superfamily MADE_1000095 71322c69598f281cd56711b67112ffc1 439 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 18 436 4.8E-123 T 13-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 MADE_1000095 71322c69598f281cd56711b67112ffc1 439 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 321 332 - T 13-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 MADE_1000095 71322c69598f281cd56711b67112ffc1 439 Gene3D G3DSA:3.40.50.150 235 437 6.7E-68 T 13-10-2018 MADE_1000095 71322c69598f281cd56711b67112ffc1 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 372 388 6.5E-29 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MADE_1000095 71322c69598f281cd56711b67112ffc1 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 6.5E-29 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MADE_1000095 71322c69598f281cd56711b67112ffc1 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 6.5E-29 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MADE_1000095 71322c69598f281cd56711b67112ffc1 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 6.5E-29 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MADE_1000095 71322c69598f281cd56711b67112ffc1 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 419 436 6.5E-29 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase MADE_1000095 71322c69598f281cd56711b67112ffc1 439 Pfam PF01029 NusB family 17 132 1.8E-16 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MADE_1000095 71322c69598f281cd56711b67112ffc1 439 Gene3D G3DSA:3.30.70.1170 177 234 2.3E-10 T 13-10-2018 MADE_1000095 71322c69598f281cd56711b67112ffc1 439 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 434 2.3E-67 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 MADE_1000095 71322c69598f281cd56711b67112ffc1 439 SUPERFAMILY SSF48013 11 153 3.66E-26 T 13-10-2018 IPR035926 NusB-like superfamily MADE_1000095 71322c69598f281cd56711b67112ffc1 439 SUPERFAMILY SSF53335 143 436 4.96E-69 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 206 281 4.4E-10 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Pfam PF13533 Biotin-lipoyl like 170 203 6.9E-6 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Gene3D G3DSA:2.40.30.170 154 167 2.2E-10 T 13-10-2018 MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Gene3D G3DSA:2.40.50.100 168 201 2.2E-10 T 13-10-2018 MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Gene3D G3DSA:2.40.50.100 205 239 9.9E-11 T 13-10-2018 MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Gene3D G3DSA:2.40.30.170 240 308 9.9E-11 T 13-10-2018 MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 SUPERFAMILY SSF51230 173 237 5.49E-8 T 13-10-2018 IPR011053 Single hybrid motif MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Gene3D G3DSA:2.40.420.20 312 393 2.0E-11 T 13-10-2018 MADE_1001810 21df0c82c5c1f5565ff06bc395e885d2 393 Gene3D G3DSA:2.40.420.20 142 153 2.2E-10 T 13-10-2018 MADE_1015750 cd33538d9399b84d7a34a5d22794504f 433 Pfam PF01204 Trehalase 106 386 5.6E-14 T 13-10-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 MADE_1015750 cd33538d9399b84d7a34a5d22794504f 433 Gene3D G3DSA:1.50.10.10 9 425 2.3E-112 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MADE_1015750 cd33538d9399b84d7a34a5d22794504f 433 SUPERFAMILY SSF48208 5 425 3.98E-70 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 SMART SM01002 149 297 6.2E-91 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 13-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 SUPERFAMILY SSF51735 137 303 1.63E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 Gene3D G3DSA:3.40.50.720 130 305 1.8E-138 T 13-10-2018 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 353 1.1E-83 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 371 1.1E-154 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 1.1E-6 T 13-10-2018 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 1.1E-6 T 13-10-2018 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 1.5E-48 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 SMART SM01003 4 137 1.6E-79 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 PIRSF PIRSF000183 1 375 2.2E-153 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 SUPERFAMILY SSF52283 1 360 8.42E-67 T 13-10-2018 MADE_1010710 2b59cd99304cdd8bd7dba0c40f48aeda 377 Gene3D G3DSA:3.40.50.720 3 353 1.8E-138 T 13-10-2018 MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Gene3D G3DSA:3.40.50.10070 22 181 6.4E-46 T 13-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 14 447 1.6E-157 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 4 446 49.518 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 SUPERFAMILY SSF69304 173 448 2.09E-60 T 13-10-2018 MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Gene3D G3DSA:2.120.10.30 183 450 4.8E-95 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 SUPERFAMILY SSF52964 28 179 1.23E-38 T 13-10-2018 MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Pfam PF07676 WD40-like Beta Propeller Repeat 213 248 2.0E-8 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Pfam PF07676 WD40-like Beta Propeller Repeat 257 292 1.5E-9 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Pfam PF07676 WD40-like Beta Propeller Repeat 300 335 3.4E-10 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Pfam PF07676 WD40-like Beta Propeller Repeat 388 412 0.18 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_000001021210 c48cbd519813a286e84aac74fb39183d 451 Pfam PF04052 TolB amino-terminal domain 23 125 4.7E-31 T 13-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 1.4E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 1.4E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.4E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.4E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.4E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.4E-34 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 SUPERFAMILY SSF51735 26 267 7.65E-68 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 35 266 1.9E-51 T 13-10-2018 MADE_1008825 eb68a1371318b5fe31823b7044d49432 268 Gene3D G3DSA:3.40.50.720 4 268 7.2E-67 T 13-10-2018 MADE_000001023395 ecad8e9ec52d8fe857df0c58eb0e2df5 127 Gene3D G3DSA:3.10.180.10 7 126 1.3E-34 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_000001023395 ecad8e9ec52d8fe857df0c58eb0e2df5 127 SUPERFAMILY SSF54593 1 126 5.24E-34 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_000001023395 ecad8e9ec52d8fe857df0c58eb0e2df5 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 1.1E-21 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 SUPERFAMILY SSF50249 67 147 2.09E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 Pfam PF00773 RNB domain 260 587 5.9E-109 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 SMART SM00316 639 722 1.4E-15 T 13-10-2018 IPR022967 RNA-binding domain, S1 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 SMART SM00955 260 588 2.1E-183 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 72 719 2.4E-253 T 13-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 SUPERFAMILY SSF50249 641 720 5.54E-23 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 SMART SM00357 150 214 4.3 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 SMART SM00357 86 145 4.8E-9 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 SUPERFAMILY SSF50249 187 640 5.63E-147 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 Gene3D G3DSA:2.40.50.140 69 148 4.7E-16 T 13-10-2018 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 Hamap MF_01895 Ribonuclease R [rnr]. 38 722 55.825 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 TIGRFAM TIGR02063 RNase_R: ribonuclease R 19 721 3.8E-270 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 Pfam PF08206 Ribonuclease B OB domain 87 141 4.3E-18 T 13-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 ProSitePatterns PS01175 Ribonuclease II family signature. 555 579 - T 13-10-2018 IPR022966 Ribonuclease II/R, conserved site MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 Gene3D G3DSA:2.40.50.140 642 752 7.1E-23 T 13-10-2018 MADE_1018020 a211c27890497c88442c1ea3aa9fb892 805 Pfam PF00575 S1 RNA binding domain 639 719 9.6E-15 T 13-10-2018 IPR003029 S1 domain GO:0003676 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 SUPERFAMILY SSF46955 2 102 1.17E-22 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 Pfam PF13411 MerR HTH family regulatory protein 2 69 8.5E-17 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 3.5E-5 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.5E-5 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 3.5E-5 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 SMART SM00422 2 70 1.1E-20 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 Gene3D G3DSA:1.10.1660.10 1 113 2.0E-24 T 13-10-2018 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 Pfam PF13649 Methyltransferase domain 187 281 7.1E-16 T 13-10-2018 MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 SUPERFAMILY SSF53335 134 388 1.17E-37 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1020370 e77bd9d7c3c531caa6ba6201b506ec11 390 Gene3D G3DSA:3.40.50.150 141 388 7.4E-61 T 13-10-2018 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 Gene3D G3DSA:3.30.360.10 175 476 4.2E-168 T 13-10-2018 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 188 488 9.9E-118 T 13-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 185 3.3E-54 T 13-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 PIRSF PIRSF000110 1 492 3.3E-173 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 SUPERFAMILY SSF51735 6 187 2.23E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 490 85.302 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 490 6.4E-185 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 165 193 2.9E-49 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 326 352 2.9E-49 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 141 154 2.9E-49 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 235 251 2.9E-49 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 217 234 2.9E-49 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 SUPERFAMILY SSF55347 175 489 7.85E-114 T 13-10-2018 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 Gene3D G3DSA:3.40.50.720 12 438 4.2E-168 T 13-10-2018 MADE_1011705 69b80430a0800ddd0195dfd0ccaeddf8 497 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 175 181 - T 13-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 MADE_000001023030 e81d6bf1c053cc8837389afad26b9954 227 SUPERFAMILY SSF52317 1 226 1.39E-73 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_000001023030 e81d6bf1c053cc8837389afad26b9954 227 Gene3D G3DSA:3.40.50.880 1 227 2.9E-78 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_000001023030 e81d6bf1c053cc8837389afad26b9954 227 Pfam PF01965 DJ-1/PfpI family 27 217 3.3E-17 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 SUPERFAMILY SSF55424 579 695 3.61E-34 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 Gene3D G3DSA:3.50.50.60 239 566 6.3E-100 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 SUPERFAMILY SSF51905 239 615 1.02E-54 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 285 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 541 548 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 579 600 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 666 686 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 372 381 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 412 437 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 260 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 500 514 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 644 659 1.3E-54 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 583 691 3.5E-26 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 412 430 2.7E-27 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 258 2.7E-27 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 526 548 2.7E-27 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 369 387 2.7E-27 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 499 515 2.7E-27 T 13-10-2018 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 Pfam PF09335 SNARE associated Golgi protein 67 183 3.1E-24 T 13-10-2018 IPR032816 SNARE associated Golgi protein MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 271 281 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 Gene3D G3DSA:3.30.390.30 582 702 8.5E-36 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 238 561 1.3E-59 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1009060 666012b1dc2a83298a3f74ba85d8da7f 717 Gene3D G3DSA:3.50.50.60 388 513 6.3E-100 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_000001022675 29fc100f047d7a23ab1ede2d9a5cbc82 149 Gene3D G3DSA:3.30.70.100 44 149 2.7E-26 T 13-10-2018 MADE_000001022675 29fc100f047d7a23ab1ede2d9a5cbc82 149 SUPERFAMILY SSF54909 47 146 1.07E-24 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel MADE_000001022675 29fc100f047d7a23ab1ede2d9a5cbc82 149 SMART SM00886 50 148 1.3E-24 T 13-10-2018 IPR013097 Stress responsive alpha-beta barrel MADE_000001022675 29fc100f047d7a23ab1ede2d9a5cbc82 149 Pfam PF07876 Stress responsive A/B Barrel Domain 50 146 2.7E-17 T 13-10-2018 IPR013097 Stress responsive alpha-beta barrel MADE_1004700 977a5e2f469c5186eee1ebc002dd7bf1 365 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 4 361 49.698 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MADE_1004700 977a5e2f469c5186eee1ebc002dd7bf1 365 SUPERFAMILY SSF53659 3 361 2.88E-121 T 13-10-2018 MADE_1004700 977a5e2f469c5186eee1ebc002dd7bf1 365 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 246 265 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MADE_1004700 977a5e2f469c5186eee1ebc002dd7bf1 365 SMART SM01329 5 357 3.4E-197 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MADE_1004700 977a5e2f469c5186eee1ebc002dd7bf1 365 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 6 356 2.8E-154 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 MADE_1004700 977a5e2f469c5186eee1ebc002dd7bf1 365 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 357 5.0E-130 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MADE_1004700 977a5e2f469c5186eee1ebc002dd7bf1 365 Gene3D G3DSA:3.40.718.10 1 364 7.2E-155 T 13-10-2018 MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 253 2.2E-48 T 13-10-2018 MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.6E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.6E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.6E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.8E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.8E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.8E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 3.8E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.8E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.8E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 Gene3D G3DSA:3.40.50.720 1 257 1.4E-73 T 13-10-2018 MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_000001021870 6b2829d6d5abdca51015f0569d04b6d9 258 SUPERFAMILY SSF51735 3 255 1.63E-64 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009435 bed51d93448109657d167c619260a67c 156 Pfam PF11143 Protein of unknown function (DUF2919) 5 150 2.1E-32 T 13-10-2018 IPR021318 Protein of unknown function DUF2919 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 Gene3D G3DSA:1.10.510.10 276 531 6.6E-39 T 13-10-2018 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 SMART SM00220 281 555 1.2E-10 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 Pfam PF00069 Protein kinase domain 292 502 4.5E-31 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 SMART SM00331 32 248 1.0E-5 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 SMART SM00332 10 246 5.6E-19 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 SUPERFAMILY SSF56112 264 543 5.66E-46 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 Pfam PF13672 Protein phosphatase 2C 46 217 7.1E-14 T 13-10-2018 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 SUPERFAMILY SSF81606 20 249 9.94E-47 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1019425 ba7d0d69113fd7becdd114133b281a44 586 Gene3D G3DSA:3.60.40.10 2 250 1.6E-44 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 Pfam PF01979 Amidohydrolase family 11 304 8.4E-15 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 ProSitePatterns PS00483 Dihydroorotase signature 2. 244 255 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 Hamap MF_00219 Dihydroorotase [pyrC]. 2 343 45.392 T 13-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 Gene3D G3DSA:3.20.20.140 2 344 7.3E-108 T 13-10-2018 MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 SUPERFAMILY SSF51556 1 342 3.79E-144 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 4 342 5.9E-134 T 13-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 PIRSF PIRSF001237 1 345 2.0E-142 T 13-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_000001023380 ea84a30723cf2ee08dc32c1568692a5d 348 ProSitePatterns PS00482 Dihydroorotase signature 1. 11 19 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007135 db3f3bbeef3ba79f3cb4dfa6ce24a5f0 504 Gene3D G3DSA:3.60.110.10 243 468 9.2E-9 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_1007135 db3f3bbeef3ba79f3cb4dfa6ce24a5f0 504 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 4 489 21.917 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MADE_1007135 db3f3bbeef3ba79f3cb4dfa6ce24a5f0 504 SUPERFAMILY SSF56317 207 477 4.32E-34 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_1007135 db3f3bbeef3ba79f3cb4dfa6ce24a5f0 504 Pfam PF00795 Carbon-nitrogen hydrolase 248 463 3.7E-26 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MADE_1007135 db3f3bbeef3ba79f3cb4dfa6ce24a5f0 504 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 56 448 7.0E-88 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SUPERFAMILY SSF47384 515 593 5.3E-17 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Gene3D G3DSA:3.30.450.20 17 259 2.1E-123 T 13-10-2018 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Pfam PF00360 Phytochrome region 340 506 5.0E-25 T 13-10-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SUPERFAMILY SSF52172 768 883 3.98E-20 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SUPERFAMILY SSF55781 145 318 1.01E-48 T 13-10-2018 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SMART SM00065 154 333 0.0047 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Gene3D G3DSA:1.10.287.130 517 592 4.8E-17 T 13-10-2018 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SUPERFAMILY SSF55781 307 504 1.86E-29 T 13-10-2018 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Pfam PF08446 PAS fold 13 125 1.5E-8 T 13-10-2018 IPR013654 PAS fold-2 GO:0006355 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Gene3D G3DSA:3.30.565.10 593 753 3.5E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Gene3D G3DSA:3.30.450.40 13 483 2.1E-123 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Gene3D G3DSA:3.30.450.270 327 500 2.1E-123 T 13-10-2018 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 689 2.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 710 728 2.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 735 748 2.0E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SUPERFAMILY SSF55874 581 749 2.23E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SMART SM00388 527 592 5.0E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SUPERFAMILY SSF55785 3 125 1.15E-21 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 638 749 6.9E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Pfam PF00512 His Kinase A (phospho-acceptor) domain 528 591 7.7E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SMART SM00448 770 883 8.5E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Pfam PF01590 GAF domain 155 303 2.1E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Gene3D G3DSA:3.40.50.2300 755 884 3.2E-20 T 13-10-2018 MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 SMART SM00387 638 751 4.7E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014245 1f019bd2f4e715c708f1931208749bb0 884 Pfam PF00072 Response regulator receiver domain 772 882 1.4E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004305 23580c100803e381b543d13a84946e9d 823 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 806 823 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site MADE_1004305 23580c100803e381b543d13a84946e9d 823 Pfam PF00593 TonB dependent receptor 301 821 4.6E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1004305 23580c100803e381b543d13a84946e9d 823 SUPERFAMILY SSF56935 58 823 1.94E-94 T 13-10-2018 MADE_1004305 23580c100803e381b543d13a84946e9d 823 Pfam PF07715 TonB-dependent Receptor Plug Domain 80 190 9.1E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1004305 23580c100803e381b543d13a84946e9d 823 Gene3D G3DSA:2.40.170.20 71 823 1.9E-109 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1016485 31123e669519fae7dba02bef7b5b19be 353 Pfam PF06054 Competence protein CoiA-like family 33 58 2.3E-6 T 13-10-2018 IPR010330 Competence-induced protein CoiA-like MADE_1010880 d856761baae17030579b40b67b01218c 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 65 165 9.0E-16 T 13-10-2018 IPR016188 PurM-like, N-terminal domain MADE_1010880 d856761baae17030579b40b67b01218c 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 8 344 46.507 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MADE_1010880 d856761baae17030579b40b67b01218c 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 339 1.4E-38 T 13-10-2018 IPR010918 PurM-like, C-terminal domain MADE_1010880 d856761baae17030579b40b67b01218c 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 334 4.0E-148 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MADE_1010880 d856761baae17030579b40b67b01218c 346 Gene3D G3DSA:3.30.1330.10 7 171 1.4E-66 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1010880 d856761baae17030579b40b67b01218c 346 SUPERFAMILY SSF55326 8 171 5.68E-52 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1010880 d856761baae17030579b40b67b01218c 346 Gene3D G3DSA:3.90.650.10 172 345 4.2E-70 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1010880 d856761baae17030579b40b67b01218c 346 SUPERFAMILY SSF56042 172 340 7.18E-61 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1012345 8094b85af15a650eb65855388c212e73 327 SUPERFAMILY SSF55120 82 319 8.63E-81 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1012345 8094b85af15a650eb65855388c212e73 327 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1012345 8094b85af15a650eb65855388c212e73 327 Pfam PF00849 RNA pseudouridylate synthase 95 245 5.8E-33 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1012345 8094b85af15a650eb65855388c212e73 327 Pfam PF01479 S4 domain 22 61 9.5E-10 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1012345 8094b85af15a650eb65855388c212e73 327 SMART SM00363 21 86 3.5E-5 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1012345 8094b85af15a650eb65855388c212e73 327 Gene3D G3DSA:3.30.2350.10 87 319 2.0E-74 T 13-10-2018 MADE_1012345 8094b85af15a650eb65855388c212e73 327 Gene3D G3DSA:3.10.290.10 6 77 8.9E-18 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MADE_1012345 8094b85af15a650eb65855388c212e73 327 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 20 315 1.1E-105 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1012345 8094b85af15a650eb65855388c212e73 327 SUPERFAMILY SSF55174 21 73 3.7E-10 T 13-10-2018 MADE_1003440 e93d7fd33039e111bfcf78bdf7ec2c1a 180 Gene3D G3DSA:3.90.79.10 1 160 9.5E-48 T 13-10-2018 MADE_1003440 e93d7fd33039e111bfcf78bdf7ec2c1a 180 PRINTS PR00502 NUDIX hydrolase family signature 47 62 8.4E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MADE_1003440 e93d7fd33039e111bfcf78bdf7ec2c1a 180 PRINTS PR00502 NUDIX hydrolase family signature 33 47 8.4E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MADE_1003440 e93d7fd33039e111bfcf78bdf7ec2c1a 180 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MADE_1003440 e93d7fd33039e111bfcf78bdf7ec2c1a 180 Pfam PF00293 NUDIX domain 7 146 6.8E-26 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MADE_1003440 e93d7fd33039e111bfcf78bdf7ec2c1a 180 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 36.583 T 13-10-2018 IPR022927 RNA pyrophosphohydrolase RppH MADE_1003440 e93d7fd33039e111bfcf78bdf7ec2c1a 180 SUPERFAMILY SSF55811 7 153 5.82E-31 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_1015945 6fdd6d8faf800c754553cda7a72fdb67 142 PIRSF PIRSF004638 1 142 5.0E-49 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 MADE_1015945 6fdd6d8faf800c754553cda7a72fdb67 142 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 142 1.6E-47 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 SUPERFAMILY SSF53850 92 304 1.95E-22 T 13-10-2018 MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 Pfam PF03466 LysR substrate binding domain 90 301 2.2E-22 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 SUPERFAMILY SSF46785 3 85 1.17E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.8E-19 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.8E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 Gene3D G3DSA:1.10.10.10 1 86 5.4E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016625 ac7283d54345ca1c44e3903582c17b47 326 Gene3D G3DSA:3.40.190.290 92 307 1.7E-23 T 13-10-2018 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 239 2.1E-69 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 34.428 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 SUPERFAMILY SSF55120 2 254 3.6E-86 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 Gene3D G3DSA:3.30.70.580 1 105 1.2E-37 T 13-10-2018 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 Pfam PF01416 tRNA pseudouridine synthase 143 245 1.1E-27 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 Pfam PF01416 tRNA pseudouridine synthase 9 103 6.2E-8 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 PIRSF PIRSF001430 1 256 3.1E-75 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1011905 feadfaffd0bb8d05925b7557e81c081a 302 Gene3D G3DSA:3.30.70.660 106 243 1.9E-46 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 MADE_1019095 fd5320c034cfbc09473395d9e752f44f 705 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 688 705 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site MADE_1019095 fd5320c034cfbc09473395d9e752f44f 705 SUPERFAMILY SSF56935 29 705 1.61E-61 T 13-10-2018 MADE_1019095 fd5320c034cfbc09473395d9e752f44f 705 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 146 6.7E-6 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1019095 fd5320c034cfbc09473395d9e752f44f 705 Pfam PF00593 TonB dependent receptor 210 704 7.2E-30 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1019095 fd5320c034cfbc09473395d9e752f44f 705 Gene3D G3DSA:2.170.130.10 40 146 6.8E-5 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1019095 fd5320c034cfbc09473395d9e752f44f 705 Gene3D G3DSA:2.40.170.20 153 705 1.9E-52 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 Gene3D G3DSA:1.10.287.110 13 124 4.1E-37 T 13-10-2018 IPR036869 Chaperone J-domain superfamily MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 Pfam PF00684 DnaJ central domain 158 218 1.1E-15 T 13-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 Gene3D G3DSA:2.10.230.10 150 220 2.1E-25 T 13-10-2018 MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 Gene3D G3DSA:2.60.260.20 266 374 1.5E-28 T 13-10-2018 MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 ProSitePatterns PS00636 Nt-dnaJ domain signature. 59 78 - T 13-10-2018 IPR018253 DnaJ domain, conserved site MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 14 383 42.54 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 SUPERFAMILY SSF57938 145 221 2.75E-23 T 13-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 SUPERFAMILY SSF49493 270 355 6.02E-22 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 Pfam PF01556 DnaJ C terminal domain 132 344 2.0E-46 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 SUPERFAMILY SSF46565 12 119 9.16E-38 T 13-10-2018 IPR036869 Chaperone J-domain superfamily MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 PRINTS PR00625 DnaJ domain signature 19 37 8.6E-32 T 13-10-2018 IPR001623 DnaJ domain MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 PRINTS PR00625 DnaJ domain signature 74 93 8.6E-32 T 13-10-2018 IPR001623 DnaJ domain MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 PRINTS PR00625 DnaJ domain signature 37 52 8.6E-32 T 13-10-2018 IPR001623 DnaJ domain MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 PRINTS PR00625 DnaJ domain signature 54 74 8.6E-32 T 13-10-2018 IPR001623 DnaJ domain MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 Pfam PF00226 DnaJ domain 17 79 1.3E-27 T 13-10-2018 IPR001623 DnaJ domain MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 17 361 4.6E-141 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 SUPERFAMILY SSF49493 125 272 3.27E-20 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 MADE_1007060 7359be78e67d8b3c25816cd5a95f84a3 389 SMART SM00271 16 74 2.5E-29 T 13-10-2018 IPR001623 DnaJ domain MADE_000001023285 13a7e95354ee516437e7cf4bf6e11774 156 PIRSF PIRSF002122 3 156 6.3E-61 T 13-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 MADE_000001023285 13a7e95354ee516437e7cf4bf6e11774 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 13-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_000001023285 13a7e95354ee516437e7cf4bf6e11774 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.836 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MADE_000001023285 13a7e95354ee516437e7cf4bf6e11774 156 SUPERFAMILY SSF47973 6 149 1.28E-59 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MADE_000001023285 13a7e95354ee516437e7cf4bf6e11774 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 9.9E-70 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 MADE_000001023285 13a7e95354ee516437e7cf4bf6e11774 156 Gene3D G3DSA:1.10.455.10 2 155 2.2E-63 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily MADE_000001023285 13a7e95354ee516437e7cf4bf6e11774 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.0E-65 T 13-10-2018 IPR023798 Ribosomal protein S7 domain MADE_1006870 feee30b88675786516d4ae54689b28e3 99 Pfam PF03795 YCII-related domain 1 94 9.8E-28 T 13-10-2018 IPR005545 YCII-related MADE_1006870 feee30b88675786516d4ae54689b28e3 99 SUPERFAMILY SSF54909 1 97 1.05E-30 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel MADE_1006870 feee30b88675786516d4ae54689b28e3 99 Gene3D G3DSA:3.30.70.1060 1 98 1.5E-35 T 13-10-2018 MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 Gene3D G3DSA:1.10.150.130 15 111 1.7E-21 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 Pfam PF00589 Phage integrase family 125 294 3.7E-57 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 15 308 57.168 T 13-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 21 307 4.8E-116 T 13-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 17 308 56.017 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 Gene3D G3DSA:1.10.443.10 123 301 1.1E-71 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 SUPERFAMILY SSF56349 20 298 9.42E-60 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1004005 2b8f0288e449224d4d86133d2c0f16f4 308 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 19 101 2.1E-22 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MADE_1016695 d299c188a442d119318513d3b7eb676a 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 1.4E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1016695 d299c188a442d119318513d3b7eb676a 197 Gene3D G3DSA:1.10.10.60 1 51 1.2E-22 T 13-10-2018 MADE_1016695 d299c188a442d119318513d3b7eb676a 197 Gene3D G3DSA:1.10.357.10 52 197 4.1E-35 T 13-10-2018 MADE_1016695 d299c188a442d119318513d3b7eb676a 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MADE_1016695 d299c188a442d119318513d3b7eb676a 197 SUPERFAMILY SSF46689 10 68 2.84E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 67 121 3.8E-17 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 Hamap MF_00422 Protein translocase subunit SecE [secE]. 64 119 12.916 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 PRINTS PR01650 Bacterial translocase SecE signature 107 123 2.0E-32 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 PRINTS PR01650 Bacterial translocase SecE signature 42 63 2.0E-32 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 PRINTS PR01650 Bacterial translocase SecE signature 63 83 2.0E-32 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 PRINTS PR01650 Bacterial translocase SecE signature 87 107 2.0E-32 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 69 97 - T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 Gene3D G3DSA:1.20.5.1030 64 121 7.9E-16 T 13-10-2018 IPR038379 SecE superfamily MADE_000001023345 8059902e91eb3e13cf6268004b2ef127 125 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 68 120 1.3E-19 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Gene3D G3DSA:2.40.50.180 802 864 2.7E-27 T 13-10-2018 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Pfam PF01584 CheW-like domain 784 910 2.3E-23 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SUPERFAMILY SSF50341 778 909 3.01E-28 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SMART SM00260 771 909 4.5E-26 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SMART SM00387 636 779 2.7E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SMART SM00073 1 98 1.4E-21 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 PRINTS PR00344 Bacterial sensor protein C-terminal signature 681 695 2.5E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 PRINTS PR00344 Bacterial sensor protein C-terminal signature 763 776 2.5E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 PRINTS PR00344 Bacterial sensor protein C-terminal signature 739 757 2.5E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SMART SM01231 523 591 3.7E-11 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 639 778 2.6E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Gene3D G3DSA:3.30.565.10 592 778 1.4E-54 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SUPERFAMILY SSF47226 1 112 3.27E-26 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SUPERFAMILY SSF55874 593 776 7.33E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Pfam PF01627 Hpt domain 3 95 5.6E-15 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 SUPERFAMILY SSF47384 524 592 1.53E-9 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Gene3D G3DSA:1.10.287.560 524 591 4.3E-9 T 13-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Gene3D G3DSA:2.30.30.40 779 905 2.7E-27 T 13-10-2018 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 525 591 1.2E-12 T 13-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 MADE_1015070 4b7d997f9794d503928f0c94ceea736a 913 Gene3D G3DSA:1.20.120.160 1 138 2.1E-30 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1008020 419f971df28e9fe9c25cdfb4ef5bd381 426 SUPERFAMILY SSF53383 14 396 1.0E-91 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1008020 419f971df28e9fe9c25cdfb4ef5bd381 426 Pfam PF00266 Aminotransferase class-V 49 223 9.5E-25 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_1008020 419f971df28e9fe9c25cdfb4ef5bd381 426 Gene3D G3DSA:3.90.1150.10 22 391 8.1E-135 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1008020 419f971df28e9fe9c25cdfb4ef5bd381 426 Gene3D G3DSA:3.40.640.10 33 294 8.1E-135 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1008020 419f971df28e9fe9c25cdfb4ef5bd381 426 PIRSF PIRSF000524 16 421 1.1E-104 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 MADE_000001021840 1ee27b829c7cc7355a374bbf38201af1 171 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 5 163 24.745 T 13-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MADE_000001021840 1ee27b829c7cc7355a374bbf38201af1 171 Gene3D G3DSA:3.30.160.150 17 166 9.7E-48 T 13-10-2018 MADE_000001021840 1ee27b829c7cc7355a374bbf38201af1 171 Pfam PF04390 Lipopolysaccharide-assembly 36 158 2.1E-12 T 13-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.4E-34 T 13-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 Gene3D G3DSA:4.10.950.10 196 274 4.4E-37 T 13-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 SMART SM01382 124 252 6.6E-96 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 SUPERFAMILY SSF50249 4 125 4.11E-49 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 13-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.635 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 PIRSF PIRSF002158 12 274 6.4E-103 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 SMART SM01383 42 118 1.3E-47 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 SUPERFAMILY SSF50104 127 272 4.39E-63 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 5 273 1.4E-132 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 Gene3D G3DSA:2.40.50.140 1 114 1.9E-49 T 13-10-2018 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 Gene3D G3DSA:2.30.30.30 115 195 6.6E-34 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 MADE_1002275 dced80a2bea16dc13556573adf82bc90 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 2.3E-58 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 MADE_1015475 63970f02489392a7466db1becbf447a7 315 Hamap MF_00384 Homoserine kinase [thrB]. 6 314 27.434 T 13-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MADE_1015475 63970f02489392a7466db1becbf447a7 315 PIRSF PIRSF000676 1 315 1.5E-76 T 13-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MADE_1015475 63970f02489392a7466db1becbf447a7 315 PRINTS PR00958 Homoserine kinase signature 103 118 2.3E-27 T 13-10-2018 MADE_1015475 63970f02489392a7466db1becbf447a7 315 PRINTS PR00958 Homoserine kinase signature 181 198 2.3E-27 T 13-10-2018 MADE_1015475 63970f02489392a7466db1becbf447a7 315 PRINTS PR00958 Homoserine kinase signature 260 275 2.3E-27 T 13-10-2018 MADE_1015475 63970f02489392a7466db1becbf447a7 315 PRINTS PR00958 Homoserine kinase signature 143 156 2.3E-27 T 13-10-2018 MADE_1015475 63970f02489392a7466db1becbf447a7 315 PRINTS PR00958 Homoserine kinase signature 11 26 2.3E-27 T 13-10-2018 MADE_1015475 63970f02489392a7466db1becbf447a7 315 Gene3D G3DSA:3.30.230.10 7 173 3.8E-85 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1015475 63970f02489392a7466db1becbf447a7 315 SUPERFAMILY SSF54211 4 164 1.97E-29 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1015475 63970f02489392a7466db1becbf447a7 315 Gene3D G3DSA:3.30.70.890 174 283 3.8E-85 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MADE_1015475 63970f02489392a7466db1becbf447a7 315 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 13-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 MADE_1015475 63970f02489392a7466db1becbf447a7 315 SUPERFAMILY SSF55060 180 294 6.62E-27 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily MADE_1015475 63970f02489392a7466db1becbf447a7 315 TIGRFAM TIGR00191 thrB: homoserine kinase 6 313 9.1E-89 T 13-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 MADE_1015475 63970f02489392a7466db1becbf447a7 315 Pfam PF00288 GHMP kinases N terminal domain 90 156 1.7E-13 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 MADE_1015475 63970f02489392a7466db1becbf447a7 315 Pfam PF08544 GHMP kinases C terminal 218 294 7.9E-12 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain MADE_1012880 68f732bd749bb6e9a52690cd38507c11 194 TIGRFAM TIGR03406 FeS_long_SufT: probable FeS assembly SUF system protein SufT 23 192 1.3E-75 T 13-10-2018 IPR017776 FeS assembly SUF system protein SufT, putative MADE_1012880 68f732bd749bb6e9a52690cd38507c11 194 Pfam PF01883 Iron-sulfur cluster assembly protein 96 170 1.8E-19 T 13-10-2018 IPR002744 MIP18 family-like MADE_1012880 68f732bd749bb6e9a52690cd38507c11 194 Gene3D G3DSA:3.30.300.130 89 193 2.5E-34 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MADE_1012880 68f732bd749bb6e9a52690cd38507c11 194 SUPERFAMILY SSF117916 94 190 9.48E-31 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MADE_1000755 45b2b04a2ea00c88f5105cc5cc646ba5 223 Pfam PF02230 Phospholipase/Carboxylesterase 12 221 2.6E-57 T 13-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 MADE_1000755 45b2b04a2ea00c88f5105cc5cc646ba5 223 SUPERFAMILY SSF53474 11 222 2.57E-48 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1000755 45b2b04a2ea00c88f5105cc5cc646ba5 223 Gene3D G3DSA:3.40.50.1820 2 223 5.4E-65 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1005715 210201312b3b9b63e4166715dbe9da2b 228 Gene3D G3DSA:2.30.30.910 88 221 1.1E-35 T 13-10-2018 MADE_1005715 210201312b3b9b63e4166715dbe9da2b 228 Pfam PF13861 FlgD Tudor-like domain 87 223 1.2E-16 T 13-10-2018 IPR025963 FlgD Tudor-like domain MADE_1005715 210201312b3b9b63e4166715dbe9da2b 228 Pfam PF13860 FlgD Ig-like domain 122 180 1.5E-18 T 13-10-2018 IPR025965 FlgD Ig-like domain MADE_1005715 210201312b3b9b63e4166715dbe9da2b 228 Pfam PF03963 Flagellar hook capping protein - N-terminal region 17 79 2.5E-20 T 13-10-2018 IPR005648 Flagellar hook capping protein MADE_1005715 210201312b3b9b63e4166715dbe9da2b 228 Gene3D G3DSA:2.60.40.4070 104 191 1.1E-35 T 13-10-2018 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SUPERFAMILY SSF56042 431 615 9.72E-54 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SUPERFAMILY SSF56042 826 1035 5.53E-51 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1295 21.247 T 13-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SUPERFAMILY SSF52317 1037 1294 8.48E-94 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Gene3D G3DSA:3.90.650.10 422 606 3.3E-55 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Gene3D G3DSA:1.10.8.750 153 213 7.7E-27 T 13-10-2018 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 432 588 1.2E-28 T 13-10-2018 IPR010918 PurM-like, C-terminal domain MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 838 959 1.1E-12 T 13-10-2018 IPR010918 PurM-like, C-terminal domain MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Gene3D G3DSA:3.40.50.880 982 1295 1.5E-135 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SMART SM01211 1041 1294 2.6E-149 T 13-10-2018 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Gene3D G3DSA:3.90.650.10 810 981 8.2E-27 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SUPERFAMILY SSF109736 156 220 4.45E-22 T 13-10-2018 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Gene3D G3DSA:3.30.1330.10 614 809 9.4E-23 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1041 1294 4.4E-106 T 13-10-2018 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1293 0.0 T 13-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SUPERFAMILY SSF55326 221 428 5.58E-64 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SUPERFAMILY SSF82697 1 152 3.71E-48 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 Gene3D G3DSA:3.30.1330.10 214 421 2.6E-41 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1005435 cc8e6de71de19309842c608344ea805e 1295 SUPERFAMILY SSF55326 622 816 6.8E-66 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1010555 ae5e53f266054231d76c5b75057bfccb 70 Gene3D G3DSA:1.10.238.160 13 69 4.2E-8 T 13-10-2018 MADE_1010555 ae5e53f266054231d76c5b75057bfccb 70 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 12 59 6.6E-20 T 13-10-2018 IPR010260 DNA-binding transcriptional activator AlpA MADE_000001021715 64ba4319e82ad9b16ba57d602e252e4a 739 Gene3D G3DSA:3.40.718.10 382 648 8.6E-6 T 13-10-2018 MADE_000001021715 64ba4319e82ad9b16ba57d602e252e4a 739 Gene3D G3DSA:3.40.718.10 146 292 1.1E-5 T 13-10-2018 MADE_000001021715 64ba4319e82ad9b16ba57d602e252e4a 739 Pfam PF03971 Monomeric isocitrate dehydrogenase 5 737 0.0 T 13-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MADE_000001021715 64ba4319e82ad9b16ba57d602e252e4a 739 SUPERFAMILY SSF53659 3 738 0.0 T 13-10-2018 MADE_000001021715 64ba4319e82ad9b16ba57d602e252e4a 739 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 738 0.0 T 13-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MADE_000001021715 64ba4319e82ad9b16ba57d602e252e4a 739 PIRSF PIRSF009407 1 739 0.0 T 13-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 MADE_1001925 ac594a625b30bb59b1ebd9f68b1717c6 117 Pfam PF13473 Cupredoxin-like domain 12 116 1.9E-25 T 13-10-2018 IPR028096 EfeO-type cupredoxin-like domain MADE_1001925 ac594a625b30bb59b1ebd9f68b1717c6 117 SUPERFAMILY SSF49503 15 116 3.86E-13 T 13-10-2018 IPR008972 Cupredoxin MADE_1001925 ac594a625b30bb59b1ebd9f68b1717c6 117 Gene3D G3DSA:2.60.40.420 23 117 1.1E-21 T 13-10-2018 IPR008972 Cupredoxin MADE_000001021510 1e46992973631228423bf5874973048e 129 SUPERFAMILY SSF55021 61 122 1.3E-16 T 13-10-2018 MADE_000001021510 1e46992973631228423bf5874973048e 129 PIRSF PIRSF008459 2 128 1.1E-36 T 13-10-2018 IPR016540 Uncharacterised conserved protein UCP008459 MADE_000001021510 1e46992973631228423bf5874973048e 129 SUPERFAMILY SSF55021 1 55 2.65E-12 T 13-10-2018 MADE_000001021510 1e46992973631228423bf5874973048e 129 Pfam PF13840 ACT domain 58 119 1.8E-16 T 13-10-2018 IPR027795 CASTOR, ACT domain MADE_000001021510 1e46992973631228423bf5874973048e 129 Gene3D G3DSA:3.30.2130.10 1 129 4.6E-35 T 13-10-2018 MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 18 415 5.4E-119 T 13-10-2018 IPR017687 Outer membrane protein assembly factor BamB MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 SMART SM00564 310 341 1.4 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 SMART SM00564 77 108 0.07 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 SMART SM00564 272 303 0.069 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 SMART SM00564 135 167 0.023 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 SMART SM00564 176 207 0.18 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 SMART SM00564 351 382 10.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 11 417 38.934 T 13-10-2018 IPR017687 Outer membrane protein assembly factor BamB MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 Gene3D G3DSA:2.130.10.10 36 418 7.1E-95 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 Pfam PF13360 PQQ-like domain 58 112 9.0E-5 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 Pfam PF13360 PQQ-like domain 122 340 1.3E-45 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat MADE_1005230 13703e6ef78ce565ff8c2082961e02ce 419 SUPERFAMILY SSF50998 50 386 1.14E-77 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MADE_1013165 84cdd95d96719562c3fda4e66fb4a3da 357 SUPERFAMILY SSF55729 148 312 4.1E-36 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1013165 84cdd95d96719562c3fda4e66fb4a3da 357 Gene3D G3DSA:3.40.630.30 142 298 1.6E-21 T 13-10-2018 MADE_1013165 84cdd95d96719562c3fda4e66fb4a3da 357 Pfam PF13480 Acetyltransferase (GNAT) domain 153 283 3.6E-14 T 13-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MADE_1010735 e1dfb8a33da28789ecfb3779ba9f7de3 85 Pfam PF06305 Lipopolysaccharide assembly protein A domain 23 84 4.2E-18 T 13-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 MADE_1010735 e1dfb8a33da28789ecfb3779ba9f7de3 85 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 1 85 16.461 T 13-10-2018 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 SMART SM01134 84 245 8.6E-49 T 13-10-2018 MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 SUPERFAMILY SSF100950 92 245 1.48E-25 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 Pfam PF00455 DeoR C terminal sensor domain 92 244 1.7E-39 T 13-10-2018 IPR014036 DeoR C-terminal sensor domain MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 ProSitePatterns PS00894 DeoR-type HTH domain signature. 10 44 - T 13-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 SMART SM00420 10 62 5.3E-15 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 Pfam PF08220 DeoR-like helix-turn-helix domain 10 61 8.5E-16 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 SUPERFAMILY SSF46785 8 67 3.72E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 42 60 7.4E-5 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1019460 1c677976758dbcdab1cff270c5b8736f 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 28 42 7.4E-5 T 13-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 MADE_1012405 d188a50c988c341625f52fc032e67f21 129 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 54 98 2.0E-9 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MADE_1012405 d188a50c988c341625f52fc032e67f21 129 Pfam PF02609 Exonuclease VII small subunit 59 110 8.1E-20 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MADE_1012405 d188a50c988c341625f52fc032e67f21 129 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 58 113 1.3E-21 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MADE_1012405 d188a50c988c341625f52fc032e67f21 129 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 58 118 15.591 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MADE_1012405 d188a50c988c341625f52fc032e67f21 129 Gene3D G3DSA:1.10.287.1040 52 127 2.2E-23 T 13-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 MADE_1012405 d188a50c988c341625f52fc032e67f21 129 SUPERFAMILY SSF116842 53 119 4.97E-20 T 13-10-2018 MADE_1012405 d188a50c988c341625f52fc032e67f21 129 PIRSF PIRSF006488 47 129 1.8E-21 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 MADE_1004875 bd2c281146d323576c5cc3cb6040b49d 335 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 227 246 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 MADE_1004875 bd2c281146d323576c5cc3cb6040b49d 335 Gene3D G3DSA:3.40.718.10 1 335 5.3E-141 T 13-10-2018 MADE_1004875 bd2c281146d323576c5cc3cb6040b49d 335 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 330 3.6E-109 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MADE_1004875 bd2c281146d323576c5cc3cb6040b49d 335 SMART SM01329 5 331 4.2E-181 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 MADE_1004875 bd2c281146d323576c5cc3cb6040b49d 335 SUPERFAMILY SSF53659 3 335 9.02E-126 T 13-10-2018 MADE_000001020830 cf2f16fa5a267e053f61ca9fe54ef60d 89 Gene3D G3DSA:1.10.443.10 3 87 3.9E-10 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_000001020830 cf2f16fa5a267e053f61ca9fe54ef60d 89 SUPERFAMILY SSF56349 15 81 1.56E-9 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_000001020830 cf2f16fa5a267e053f61ca9fe54ef60d 89 Pfam PF00589 Phage integrase family 13 63 4.7E-5 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 SUPERFAMILY SSF53706 4 1074 0.0 T 13-10-2018 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 1.3E-18 T 13-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 Pfam PF01568 Molydopterin dinucleotide binding domain 1093 1207 1.7E-19 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1240 0.0 T 13-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 Pfam PF00384 Molybdopterin oxidoreductase 108 837 9.3E-168 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 781 798 - T 13-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 SUPERFAMILY SSF50692 1087 1240 1.15E-44 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 Gene3D G3DSA:3.40.50.12440 44 1250 0.0 T 13-10-2018 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 SMART SM00926 43 105 2.0E-8 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 13-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 MADE_1019275 5e59583b04e302cfbacd4bbdb806e9cc 1258 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1130 1157 - T 13-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.91 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 4.5E-42 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 13-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 Pfam PF01016 Ribosomal L27 protein 2 82 1.6E-38 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 1.0E-17 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 Gene3D G3DSA:2.40.50.100 21 85 3.4E-30 T 13-10-2018 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.3E-37 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.3E-37 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.3E-37 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003340 d06e9bfab7dc88e1604623c978d9b335 85 SUPERFAMILY SSF110324 2 82 2.02E-33 T 13-10-2018 MADE_000001023155 5c175c5c0b70fc02927d1f16b0f504ca 354 SMART SM01358 29 259 1.9E-8 T 13-10-2018 IPR032255 Helical bimodular sensor domain MADE_1014025 78797aaa4364af29a917c346975008b1 266 Pfam PF08223 PaaX-like protein C-terminal domain 173 260 2.5E-6 T 13-10-2018 IPR013225 PaaX-like, C-terminal MADE_1014025 78797aaa4364af29a917c346975008b1 266 Gene3D G3DSA:1.10.10.10 10 75 2.0E-5 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 SMART SM00490 311 396 3.2E-16 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 Pfam PF00271 Helicase conserved C-terminal domain 288 391 2.7E-17 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 Pfam PF08494 DEAD/H associated 638 821 1.1E-38 T 13-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 Pfam PF00270 DEAD/DEAH box helicase 21 238 6.4E-20 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 SMART SM00487 15 270 4.5E-26 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 PIRSF PIRSF037307 1 856 1.1E-182 T 13-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 Gene3D G3DSA:3.40.50.300 282 424 1.4E-25 T 13-10-2018 MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 SUPERFAMILY SSF52540 114 394 2.1E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023445 3d0277c04e7a317ba52dc8df2cfc1882 868 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 110 846 7.3E-292 T 13-10-2018 IPR026362 DEXH box helicase, DNA ligase-associated MADE_1015905 7ab755a6167ebff3e4ccbd86a728e46a 279 Gene3D G3DSA:3.40.50.300 6 267 6.7E-92 T 13-10-2018 MADE_1015905 7ab755a6167ebff3e4ccbd86a728e46a 279 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 24 243 8.5E-78 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related MADE_1015905 7ab755a6167ebff3e4ccbd86a728e46a 279 SUPERFAMILY SSF52540 54 244 5.8E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015905 7ab755a6167ebff3e4ccbd86a728e46a 279 PIRSF PIRSF028756 5 276 7.0E-72 T 13-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 2.7E-87 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 SMART SM00363 96 160 2.1E-20 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.97 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 Pfam PF01479 S4 domain 96 143 2.3E-20 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 Gene3D G3DSA:3.10.290.10 95 191 1.8E-81 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 Gene3D G3DSA:1.10.1050.10 6 206 1.8E-81 T 13-10-2018 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 SUPERFAMILY SSF55174 3 206 1.7E-74 T 13-10-2018 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 1.4E-33 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 13-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013940 b02054c0e861081b087366f16f80f1ea 206 SMART SM01390 3 95 4.5E-52 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 MADE_1012715 4f4b2eec44389177b689860eba1c4aef 585 SUPERFAMILY SSF69593 43 276 5.1E-15 T 13-10-2018 MADE_1012715 4f4b2eec44389177b689860eba1c4aef 585 Pfam PF13444 Acetyltransferase (GNAT) domain 337 437 1.0E-22 T 13-10-2018 MADE_1012715 4f4b2eec44389177b689860eba1c4aef 585 Pfam PF01553 Acyltransferase 83 208 1.3E-10 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1012715 4f4b2eec44389177b689860eba1c4aef 585 SMART SM00563 94 211 5.3E-8 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1012715 4f4b2eec44389177b689860eba1c4aef 585 SUPERFAMILY SSF55729 319 475 4.77E-23 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1019085 4cec705bc01b401735655fcd200039df 448 Gene3D G3DSA:3.40.50.300 118 299 1.2E-61 T 13-10-2018 MADE_1019085 4cec705bc01b401735655fcd200039df 448 Gene3D G3DSA:1.10.8.60 300 370 5.3E-20 T 13-10-2018 MADE_1019085 4cec705bc01b401735655fcd200039df 448 SUPERFAMILY SSF52540 129 366 2.24E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019085 4cec705bc01b401735655fcd200039df 448 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 153 166 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MADE_1019085 4cec705bc01b401735655fcd200039df 448 SMART SM00382 149 292 1.8E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1019085 4cec705bc01b401735655fcd200039df 448 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 215 230 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_1019085 4cec705bc01b401735655fcd200039df 448 Gene3D G3DSA:1.10.10.60 398 446 2.1E-7 T 13-10-2018 MADE_1019085 4cec705bc01b401735655fcd200039df 448 Pfam PF02954 Bacterial regulatory protein, Fis family 402 441 4.2E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1019085 4cec705bc01b401735655fcd200039df 448 Pfam PF00158 Sigma-54 interaction domain 129 295 5.5E-64 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1019085 4cec705bc01b401735655fcd200039df 448 SUPERFAMILY SSF46689 338 444 2.06E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1019085 4cec705bc01b401735655fcd200039df 448 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 337 346 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_1010775 0204659da6476e06a8aea47626496c4f 376 SUPERFAMILY SSF47240 3 341 5.31E-114 T 13-10-2018 IPR009078 Ferritin-like superfamily MADE_1010775 0204659da6476e06a8aea47626496c4f 376 Gene3D G3DSA:1.10.620.20 2 340 6.2E-144 T 13-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 MADE_1010775 0204659da6476e06a8aea47626496c4f 376 Pfam PF00268 Ribonucleotide reductase, small chain 33 332 6.4E-49 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 MADE_1013415 80ea2a7aabc53988347b53e389a720da 199 SUPERFAMILY SSF109604 5 186 2.28E-48 T 13-10-2018 MADE_1013415 80ea2a7aabc53988347b53e389a720da 199 SMART SM00471 27 152 3.2E-8 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1013415 80ea2a7aabc53988347b53e389a720da 199 Gene3D G3DSA:1.10.3210.10 2 199 1.9E-84 T 13-10-2018 MADE_1013415 80ea2a7aabc53988347b53e389a720da 199 Pfam PF13023 HD domain 12 170 8.4E-20 T 13-10-2018 IPR006674 HD domain MADE_1013415 80ea2a7aabc53988347b53e389a720da 199 Hamap MF_01100 5'-deoxynucleotidase YfbR [yfbR]. 4 196 42.441 T 13-10-2018 IPR022971 5'-deoxynucleotidase YfbR KEGG: 00240+3.1.3.89 MADE_1013415 80ea2a7aabc53988347b53e389a720da 199 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 81 177 1.0E-30 T 13-10-2018 MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 SUPERFAMILY SSF117892 104 236 2.88E-21 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 PRINTS PR00721 Stomatin signature 125 146 1.0E-5 T 13-10-2018 IPR001972 Stomatin family GO:0016020 MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 PRINTS PR00721 Stomatin signature 78 100 1.0E-5 T 13-10-2018 IPR001972 Stomatin family GO:0016020 MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 PRINTS PR00721 Stomatin signature 207 225 1.0E-5 T 13-10-2018 IPR001972 Stomatin family GO:0016020 MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 SMART SM00244 71 231 1.5E-38 T 13-10-2018 IPR001107 Band 7 domain MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 Pfam PF01145 SPFH domain / Band 7 family 75 246 4.7E-25 T 13-10-2018 IPR001107 Band 7 domain MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 Pfam PF12221 Bacterial membrane protein N terminal 1 43 4.2E-11 T 13-10-2018 IPR020980 Menbrane protein HflK, N-terminal MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 Gene3D G3DSA:3.30.479.30 100 233 4.4E-18 T 13-10-2018 MADE_000001023540 d2b07494462eb42aefc6697b052136cf 383 TIGRFAM TIGR01933 hflK: HflK protein 73 333 1.3E-108 T 13-10-2018 IPR010201 HflK GO:0016021 MADE_000001021550 8f2ac0e015caf9a94737b91e200aa813 516 Pfam PF00563 EAL domain 274 503 2.8E-51 T 13-10-2018 IPR001633 EAL domain MADE_000001021550 8f2ac0e015caf9a94737b91e200aa813 516 Pfam PF12792 CSS motif domain associated with EAL 42 175 5.2E-21 T 13-10-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain MADE_000001021550 8f2ac0e015caf9a94737b91e200aa813 516 SMART SM00052 267 508 5.5E-59 T 13-10-2018 IPR001633 EAL domain MADE_000001021550 8f2ac0e015caf9a94737b91e200aa813 516 Gene3D G3DSA:3.20.20.450 265 515 1.6E-64 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001021550 8f2ac0e015caf9a94737b91e200aa813 516 SUPERFAMILY SSF141868 273 513 5.49E-61 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000315 d6835a97d60b975470e6e86a40bc0891 398 Gene3D G3DSA:3.40.640.10 58 296 3.3E-134 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1000315 d6835a97d60b975470e6e86a40bc0891 398 Gene3D G3DSA:3.90.1150.10 40 387 3.3E-134 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1000315 d6835a97d60b975470e6e86a40bc0891 398 SUPERFAMILY SSF53383 5 396 7.31E-122 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1000315 d6835a97d60b975470e6e86a40bc0891 398 Pfam PF00155 Aminotransferase class I and II 43 386 7.3E-75 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1000315 d6835a97d60b975470e6e86a40bc0891 398 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MADE_1000315 d6835a97d60b975470e6e86a40bc0891 398 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 7 397 4.4E-211 T 13-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 MADE_1000315 d6835a97d60b975470e6e86a40bc0891 398 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 395 53.92 T 13-10-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 Pfam PF00614 Phospholipase D Active site motif 132 155 1.8E-5 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 SMART SM00155 132 159 0.007 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 SMART SM00155 358 385 8.1E-4 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 Gene3D G3DSA:3.30.870.10 256 417 2.8E-18 T 13-10-2018 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 Pfam PF09335 SNARE associated Golgi protein 558 674 3.1E-17 T 13-10-2018 IPR032816 SNARE associated Golgi protein MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 Gene3D G3DSA:3.30.870.10 10 228 4.3E-23 T 13-10-2018 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 Pfam PF13091 PLD-like domain 267 397 2.6E-12 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 SUPERFAMILY SSF56024 260 423 3.81E-20 T 13-10-2018 MADE_1016615 86f682e9cb466a5fc7b0718a77bb56b0 738 SUPERFAMILY SSF56024 7 252 3.41E-25 T 13-10-2018 MADE_1000665 7b36bdfa98b5828cc50640cf48931584 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 74 9.0E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1000665 7b36bdfa98b5828cc50640cf48931584 311 Gene3D G3DSA:1.10.10.10 6 96 3.1E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1000665 7b36bdfa98b5828cc50640cf48931584 311 Pfam PF03466 LysR substrate binding domain 104 302 3.7E-16 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1000665 7b36bdfa98b5828cc50640cf48931584 311 Gene3D G3DSA:3.40.190.10 179 275 8.2E-46 T 13-10-2018 MADE_1000665 7b36bdfa98b5828cc50640cf48931584 311 SUPERFAMILY SSF46785 13 93 2.0E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1000665 7b36bdfa98b5828cc50640cf48931584 311 Gene3D G3DSA:3.40.190.10 98 300 8.2E-46 T 13-10-2018 MADE_1000665 7b36bdfa98b5828cc50640cf48931584 311 SUPERFAMILY SSF53850 98 301 9.77E-32 T 13-10-2018 MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 Gene3D G3DSA:3.40.1350.30 175 312 6.4E-98 T 13-10-2018 MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 411 441 - T 13-10-2018 IPR030390 RNA methyltransferase TrmA, active site MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 65 472 2.7E-88 T 13-10-2018 MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 SUPERFAMILY SSF50249 59 107 5.14E-6 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 Gene3D G3DSA:2.40.50.140 39 127 8.6E-18 T 13-10-2018 MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 Gene3D G3DSA:3.40.50.150 128 474 6.4E-98 T 13-10-2018 MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 306 477 1.9E-17 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 SUPERFAMILY SSF53335 116 478 1.53E-64 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1004040 5f121e18de6ef6f7ef5bbf3b9b384471 482 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 59 480 60.074 T 13-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 MADE_1002090 a1cb9ce4d75f06432b505b74fd5d09ff 384 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 148 236 3.2E-5 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MADE_1002090 a1cb9ce4d75f06432b505b74fd5d09ff 384 Gene3D G3DSA:3.30.360.10 141 375 6.3E-117 T 13-10-2018 MADE_1002090 a1cb9ce4d75f06432b505b74fd5d09ff 384 SUPERFAMILY SSF55347 142 316 4.91E-33 T 13-10-2018 MADE_1002090 a1cb9ce4d75f06432b505b74fd5d09ff 384 Gene3D G3DSA:3.40.50.720 9 351 6.3E-117 T 13-10-2018 MADE_1002090 a1cb9ce4d75f06432b505b74fd5d09ff 384 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 131 1.5E-17 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MADE_1002090 a1cb9ce4d75f06432b505b74fd5d09ff 384 SUPERFAMILY SSF51735 3 167 3.26E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013015 32f1fe37ced0dad3a9b75ebababc7d7f 179 SUPERFAMILY SSF144091 10 178 4.45E-25 T 13-10-2018 MADE_1013015 32f1fe37ced0dad3a9b75ebababc7d7f 179 Pfam PF01694 Rhomboid family 48 178 2.4E-19 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MADE_1013015 32f1fe37ced0dad3a9b75ebababc7d7f 179 Gene3D G3DSA:1.20.1540.10 7 178 6.0E-13 T 13-10-2018 IPR035952 Rhomboid-like superfamily MADE_1003095 5753329496ca941501c048e492b77386 77 SUPERFAMILY SSF47598 5 40 1.96E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1005335 e59018739ce0243658d76849d0fab04f 185 SUPERFAMILY SSF55194 3 184 7.33E-69 T 13-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 MADE_1005335 e59018739ce0243658d76849d0fab04f 185 Gene3D G3DSA:3.30.1360.40 31 105 1.6E-65 T 13-10-2018 MADE_1005335 e59018739ce0243658d76849d0fab04f 185 Gene3D G3DSA:1.10.132.20 12 182 1.6E-65 T 13-10-2018 MADE_1005335 e59018739ce0243658d76849d0fab04f 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.4E-73 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MADE_1005335 e59018739ce0243658d76849d0fab04f 185 Pfam PF01765 Ribosome recycling factor 20 183 1.4E-60 T 13-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 MADE_1005335 e59018739ce0243658d76849d0fab04f 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.964 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 MADE_1009160 3a831ecbfdfcacacdb21a141b1c92302 407 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 17 342 1.7E-53 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MADE_1009160 3a831ecbfdfcacacdb21a141b1c92302 407 Gene3D G3DSA:3.20.20.70 5 354 8.5E-112 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1009160 3a831ecbfdfcacacdb21a141b1c92302 407 SUPERFAMILY SSF51395 5 350 1.31E-99 T 13-10-2018 MADE_1012585 58014e6f22f227dd6a3d8f35b4046fda 278 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 274 45.9 T 13-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 MADE_1012585 58014e6f22f227dd6a3d8f35b4046fda 278 Gene3D G3DSA:3.40.50.620 1 276 4.8E-83 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1012585 58014e6f22f227dd6a3d8f35b4046fda 278 TIGRFAM TIGR00552 nadE: NAD+ synthetase 22 274 4.4E-68 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 MADE_1012585 58014e6f22f227dd6a3d8f35b4046fda 278 SUPERFAMILY SSF52402 3 276 1.79E-79 T 13-10-2018 MADE_1012585 58014e6f22f227dd6a3d8f35b4046fda 278 Pfam PF02540 NAD synthase 22 268 2.5E-65 T 13-10-2018 IPR022310 NAD/GMP synthase MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Gene3D G3DSA:3.10.196.10 559 872 1.5E-141 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 SUPERFAMILY SSF51717 8 282 5.76E-94 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Gene3D G3DSA:3.20.20.20 2 295 1.6E-133 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Pfam PF02310 B12 binding domain 399 492 2.8E-20 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 SUPERFAMILY SSF47644 302 389 1.57E-29 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Gene3D G3DSA:3.40.50.280 394 546 1.8E-56 T 13-10-2018 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Pfam PF02607 B12 binding domain 310 382 3.7E-26 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Gene3D G3DSA:1.10.1240.10 299 387 5.9E-41 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 SMART SM01018 307 390 1.5E-45 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 TIGRFAM TIGR02082 metH: methionine synthase 5 842 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 587 858 7.7E-124 T 13-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Pfam PF00809 Pterin binding enzyme 12 250 1.2E-60 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 Gene3D G3DSA:1.10.288.10 586 742 1.5E-141 T 13-10-2018 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 SUPERFAMILY SSF52242 393 545 6.41E-47 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 SUPERFAMILY SSF56507 553 872 5.23E-127 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1006040 29abceac43d07e34dac215ca7e006270 874 PIRSF PIRSF000381 2 845 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1016515 eae3363fed56c3b667a7fdedf4132a32 85 SMART SM00966 6 51 6.8E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MADE_1016515 eae3363fed56c3b667a7fdedf4132a32 85 SUPERFAMILY SSF89447 1 70 1.62E-17 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily MADE_1016515 eae3363fed56c3b667a7fdedf4132a32 85 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 49 1.2E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 MADE_1016515 eae3363fed56c3b667a7fdedf4132a32 85 Gene3D G3DSA:2.10.260.10 1 84 4.8E-19 T 13-10-2018 MADE_1009520 789be795728819590a7e9196da1cb0ac 506 Pfam PF04820 Tryptophan halogenase 11 465 3.3E-183 T 13-10-2018 IPR006905 Flavin-dependent halogenase MADE_1009520 789be795728819590a7e9196da1cb0ac 506 Gene3D G3DSA:3.50.50.60 5 500 1.1E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009520 789be795728819590a7e9196da1cb0ac 506 SUPERFAMILY SSF51905 9 414 6.39E-27 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009520 789be795728819590a7e9196da1cb0ac 506 PIRSF PIRSF011396 4 502 3.1E-198 T 13-10-2018 IPR033856 Flavin-dependent tryptophan halogenase MADE_1020275 7257a0bb25ae5cdcc5bafc5979032bbe 213 SUPERFAMILY SSF53271 2 211 1.42E-46 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like MADE_1020275 7257a0bb25ae5cdcc5bafc5979032bbe 213 Pfam PF00156 Phosphoribosyl transferase domain 47 156 1.2E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MADE_1020275 7257a0bb25ae5cdcc5bafc5979032bbe 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 33.402 T 13-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1020275 7257a0bb25ae5cdcc5bafc5979032bbe 213 Gene3D G3DSA:3.40.50.2020 1 213 3.3E-74 T 13-10-2018 MADE_1020275 7257a0bb25ae5cdcc5bafc5979032bbe 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 187 1.9E-63 T 13-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1018040 d50e769e22bb4541b13f97888cbf3b23 98 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 2 94 3.3E-9 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1018040 d50e769e22bb4541b13f97888cbf3b23 98 Gene3D G3DSA:3.30.2310.20 1 95 2.8E-19 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1018040 d50e769e22bb4541b13f97888cbf3b23 98 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 94 6.9E-11 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1002940 1dd3a80af628839b6938139f1c7d58d8 468 SUPERFAMILY SSF53720 22 455 4.06E-118 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1002940 1dd3a80af628839b6938139f1c7d58d8 468 Gene3D G3DSA:3.40.605.10 26 440 2.5E-175 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1002940 1dd3a80af628839b6938139f1c7d58d8 468 PIRSF PIRSF036492 5 468 1.6E-189 T 13-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 MADE_1002940 1dd3a80af628839b6938139f1c7d58d8 468 Gene3D G3DSA:3.40.309.10 225 420 2.5E-175 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_1002940 1dd3a80af628839b6938139f1c7d58d8 468 Pfam PF00171 Aldehyde dehydrogenase family 25 440 4.0E-81 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_1002940 1dd3a80af628839b6938139f1c7d58d8 468 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 221 228 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 73.76 T 13-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 5.6E-30 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 Gene3D G3DSA:3.80.30.20 145 377 7.4E-80 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 SUPERFAMILY SSF102114 129 372 2.35E-61 T 13-10-2018 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 Gene3D G3DSA:3.40.50.12160 3 134 6.4E-34 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 Pfam PF01938 TRAM domain 379 440 2.7E-20 T 13-10-2018 IPR002792 TRAM domain MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 1.3E-151 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 2.1E-201 T 13-10-2018 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 SMART SM00729 147 367 4.3E-59 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1007155 8e9f7211de68f355af1a9717ce7e58bd 477 Pfam PF04055 Radical SAM superfamily 151 325 3.6E-28 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1001065 fe85a0ac0f4ad2bacb85c18b38a3368b 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.764 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MADE_1001065 fe85a0ac0f4ad2bacb85c18b38a3368b 176 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MADE_1001065 fe85a0ac0f4ad2bacb85c18b38a3368b 176 Pfam PF00719 Inorganic pyrophosphatase 18 173 2.9E-54 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MADE_1001065 fe85a0ac0f4ad2bacb85c18b38a3368b 176 Gene3D G3DSA:3.90.80.10 1 175 1.5E-71 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MADE_1001065 fe85a0ac0f4ad2bacb85c18b38a3368b 176 SUPERFAMILY SSF50324 4 173 1.57E-66 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 Gene3D G3DSA:3.40.190.10 64 279 8.9E-52 T 13-10-2018 MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 SUPERFAMILY SSF53850 65 282 1.83E-40 T 13-10-2018 MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 SMART SM00267 335 502 8.6E-17 T 13-10-2018 IPR000160 GGDEF domain MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 280 6.6E-29 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 Gene3D G3DSA:3.40.190.10 149 242 8.9E-52 T 13-10-2018 MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 SUPERFAMILY SSF55073 352 500 6.59E-22 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 SMART SM00062 64 283 1.5E-19 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 344 499 5.1E-22 T 13-10-2018 IPR000160 GGDEF domain MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 Gene3D G3DSA:3.30.70.270 332 502 1.5E-25 T 13-10-2018 MADE_1008470 92f900e02271d103ed40b6fb75f36de4 503 Pfam PF00990 Diguanylate cyclase, GGDEF domain 347 496 4.1E-18 T 13-10-2018 IPR000160 GGDEF domain MADE_1005945 30628f9f7d15599a45063d71ace66f49 150 Pfam PF04347 Flagellar biosynthesis protein, FliO 43 130 5.4E-16 T 13-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 MADE_1005945 30628f9f7d15599a45063d71ace66f49 150 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 31 97 3.2E-20 T 13-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 20 106 5.7E-16 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 SMART SM00642 183 557 1.8E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 SUPERFAMILY SSF81296 16 136 2.33E-32 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 Gene3D G3DSA:3.20.20.80 137 580 3.5E-155 T 13-10-2018 MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 SUPERFAMILY SSF51011 587 688 6.26E-18 T 13-10-2018 MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 Gene3D G3DSA:2.60.40.1180 586 688 7.7E-15 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 16 681 2.8E-236 T 13-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 Pfam PF00128 Alpha amylase, catalytic domain 188 282 4.8E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 SUPERFAMILY SSF51445 133 572 1.15E-111 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1011660 c4dbd9d3690a7ee303c6149041d28f1e 695 Gene3D G3DSA:2.60.40.10 10 135 2.7E-34 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 3.2E-142 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.47 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 Gene3D G3DSA:3.60.150.10 1 363 6.4E-156 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 SUPERFAMILY SSF103263 4 352 3.92E-147 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 Pfam PF01264 Chorismate synthase 10 345 5.0E-141 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1006530 9fad215feac03f635807eb3bc5cf2aa9 365 PIRSF PIRSF001456 3 362 4.0E-142 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 Gene3D G3DSA:3.50.50.60 4 317 2.4E-118 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PIRSF PIRSF000350 1 445 6.1E-87 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 Gene3D G3DSA:3.30.390.30 337 449 1.5E-47 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 448 3.6E-212 T 13-10-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 Gene3D G3DSA:3.50.50.60 143 260 2.4E-118 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 SUPERFAMILY SSF51905 1 358 1.78E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 7.8E-27 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 7.8E-27 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 7.8E-27 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 7.8E-27 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.8E-27 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 317 6.3E-65 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.2E-65 T 13-10-2018 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 448 1.1E-33 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MADE_1018190 3ccdc6ef03500b7b1496ec4ce8f96a72 449 SUPERFAMILY SSF55424 335 448 7.04E-35 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 SUPERFAMILY SSF56322 16 542 3.14E-146 T 13-10-2018 IPR005801 ADC synthase GO:0009058 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 PRINTS PR00095 Anthranilate synthase component I signature 395 408 1.5E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 PRINTS PR00095 Anthranilate synthase component I signature 381 394 1.5E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 PRINTS PR00095 Anthranilate synthase component I signature 475 489 1.5E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 PRINTS PR00095 Anthranilate synthase component I signature 490 504 1.5E-21 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 PIRSF PIRSF001373 3 551 6.1E-243 T 13-10-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 Gene3D G3DSA:3.60.120.10 8 550 1.7E-174 T 13-10-2018 IPR005801 ADC synthase GO:0009058 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 Pfam PF00425 chorismate binding enzyme 273 533 1.1E-83 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 Pfam PF04715 Anthranilate synthase component I, N terminal region 23 200 1.1E-17 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1006900 a9510d5ef38bb4e553e54df02a2f20d0 562 TIGRFAM TIGR00565 trpE_proteo: anthranilate synthase component I 22 543 1.7E-212 T 13-10-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 Gene3D G3DSA:3.30.420.10 4 189 2.2E-14 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 SMART SM00482 361 613 4.1E-9 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 Gene3D G3DSA:3.30.70.370 341 629 2.6E-29 T 13-10-2018 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 PRINTS PR00868 DNA-polymerase family A (pol I) signature 405 418 2.8E-5 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 PRINTS PR00868 DNA-polymerase family A (pol I) signature 430 455 2.8E-5 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 PRINTS PR00868 DNA-polymerase family A (pol I) signature 375 398 2.8E-5 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 Gene3D G3DSA:1.10.150.20 384 576 2.6E-29 T 13-10-2018 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 Pfam PF00476 DNA polymerase family A 244 640 1.3E-25 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 SUPERFAMILY SSF56672 173 649 4.23E-48 T 13-10-2018 MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 SUPERFAMILY SSF53098 45 194 3.14E-13 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_000001022515 545fbf2295878fdd53ebadadf22d4149 650 Pfam PF01612 3'-5' exonuclease 54 172 3.0E-6 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 MADE_1006395 2eddffd85039614454caa98e65ffdf79 423 Pfam PF08388 Group II intron, maturase-specific domain 293 367 2.8E-17 T 13-10-2018 IPR013597 Group II intron, maturase-specific MADE_1006395 2eddffd85039614454caa98e65ffdf79 423 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 16 355 4.8E-123 T 13-10-2018 IPR030931 Group II intron reverse transcriptase/maturase MADE_1006395 2eddffd85039614454caa98e65ffdf79 423 SUPERFAMILY SSF56672 20 367 3.21E-52 T 13-10-2018 MADE_1006395 2eddffd85039614454caa98e65ffdf79 423 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 71 280 2.9E-43 T 13-10-2018 IPR000477 Reverse transcriptase domain MADE_1010005 282c09c48baaf118d16285f934c6a16f 241 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 241 116.2 T 13-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MADE_1010005 282c09c48baaf118d16285f934c6a16f 241 SUPERFAMILY SSF56300 5 220 1.39E-28 T 13-10-2018 MADE_1010005 282c09c48baaf118d16285f934c6a16f 241 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 4 232 1.4E-95 T 13-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 MADE_1010005 282c09c48baaf118d16285f934c6a16f 241 Gene3D G3DSA:3.60.21.10 4 238 7.7E-15 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like MADE_1010005 282c09c48baaf118d16285f934c6a16f 241 Pfam PF00149 Calcineurin-like phosphoesterase 5 199 3.6E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MADE_000001022935 071d5cc84cc1f7e35dd149d371b731bd 296 Pfam PF00753 Metallo-beta-lactamase superfamily 56 230 9.7E-17 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_000001022935 071d5cc84cc1f7e35dd149d371b731bd 296 SUPERFAMILY SSF56281 3 293 1.06E-55 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_000001022935 071d5cc84cc1f7e35dd149d371b731bd 296 SMART SM00849 56 230 5.4E-29 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_000001022935 071d5cc84cc1f7e35dd149d371b731bd 296 Gene3D G3DSA:3.60.15.10 39 256 1.3E-50 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1015625 58faebf13f2d2530d9e7c64d9698b0ed 113 SUPERFAMILY SSF52980 8 108 9.98E-21 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MADE_1015625 58faebf13f2d2530d9e7c64d9698b0ed 113 Pfam PF02021 Uncharacterised protein family UPF0102 9 101 1.1E-24 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 MADE_1015625 58faebf13f2d2530d9e7c64d9698b0ed 113 Gene3D G3DSA:3.40.1350.10 8 112 6.7E-26 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MADE_1015625 58faebf13f2d2530d9e7c64d9698b0ed 113 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 4 110 1.6E-20 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 MADE_1015625 58faebf13f2d2530d9e7c64d9698b0ed 113 Hamap MF_00048 UPF0102 protein YraN [yraN]. 2 113 18.203 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 Gene3D G3DSA:3.10.25.10 208 312 2.1E-35 T 13-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 Gene3D G3DSA:3.40.50.170 1 207 5.7E-85 T 13-10-2018 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 Pfam PF02911 Formyl transferase, C-terminal domain 205 301 7.8E-30 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 305 37.331 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 SUPERFAMILY SSF53328 4 205 2.75E-67 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 SUPERFAMILY SSF50486 206 309 6.75E-33 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 308 1.8E-107 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 MADE_1000100 cec1b3040ef5bba3135b66777c487793 316 Pfam PF00551 Formyl transferase 7 184 1.6E-52 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1004850 38a1bcd2e5513ba8adb2cdf68b788ba3 353 ProSitePatterns PS01348 MraY family signature 2. 150 161 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1004850 38a1bcd2e5513ba8adb2cdf68b788ba3 353 Hamap MF_02030 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase [wecA]. 9 353 25.549 T 13-10-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819|MetaCyc: PWY-7905 MADE_1004850 38a1bcd2e5513ba8adb2cdf68b788ba3 353 TIGRFAM TIGR02380 ECA_wecA: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 10 350 1.2E-108 T 13-10-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819|MetaCyc: PWY-7905 MADE_1004850 38a1bcd2e5513ba8adb2cdf68b788ba3 353 Pfam PF00953 Glycosyl transferase family 4 75 233 1.5E-30 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 MADE_1006475 45e02014844be0357d2fbca5335c6ca9 313 SUPERFAMILY SSF51735 3 155 6.13E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1006475 45e02014844be0357d2fbca5335c6ca9 313 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 189 311 5.6E-35 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain MADE_1006475 45e02014844be0357d2fbca5335c6ca9 313 Gene3D G3DSA:3.40.50.720 3 172 1.5E-33 T 13-10-2018 MADE_1006475 45e02014844be0357d2fbca5335c6ca9 313 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 150 8.9E-18 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain MADE_1006475 45e02014844be0357d2fbca5335c6ca9 313 Gene3D G3DSA:1.10.1040.10 189 312 3.7E-39 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_1006475 45e02014844be0357d2fbca5335c6ca9 313 SUPERFAMILY SSF48179 189 311 6.46E-35 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1006475 45e02014844be0357d2fbca5335c6ca9 313 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 312 1.3E-61 T 13-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 MADE_1013650 f63622c6229a317d7c2da7941157e67c 559 Gene3D G3DSA:3.30.300.30 438 544 9.4E-8 T 13-10-2018 MADE_1013650 f63622c6229a317d7c2da7941157e67c 559 SUPERFAMILY SSF56801 15 550 3.14E-112 T 13-10-2018 MADE_1013650 f63622c6229a317d7c2da7941157e67c 559 Gene3D G3DSA:3.40.50.12780 8 433 4.3E-83 T 13-10-2018 MADE_1013650 f63622c6229a317d7c2da7941157e67c 559 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 13-10-2018 IPR020845 AMP-binding, conserved site MADE_1013650 f63622c6229a317d7c2da7941157e67c 559 Pfam PF00501 AMP-binding enzyme 26 437 8.6E-90 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_000001022610 2f645c003589c4d99575dc842addc688 256 Gene3D G3DSA:3.10.20.310 53 123 2.5E-19 T 13-10-2018 MADE_000001022610 2f645c003589c4d99575dc842addc688 256 Gene3D G3DSA:3.40.50.11690 124 251 7.2E-39 T 13-10-2018 MADE_000001022610 2f645c003589c4d99575dc842addc688 256 Pfam PF08478 POTRA domain, FtsQ-type 55 123 1.3E-13 T 13-10-2018 IPR013685 POTRA domain, FtsQ-type MADE_000001022610 2f645c003589c4d99575dc842addc688 256 Pfam PF03799 Cell division protein FtsQ 127 237 1.7E-21 T 13-10-2018 IPR005548 Cell division protein FtsQ/DivIB MADE_000001022610 2f645c003589c4d99575dc842addc688 256 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 24 245 19.707 T 13-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 Pfam PF02581 Thiamine monophosphate synthase 337 506 5.8E-56 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 319 524 19.92 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 Gene3D G3DSA:3.20.20.70 318 524 2.0E-60 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 Gene3D G3DSA:3.40.1190.20 2 273 1.5E-61 T 13-10-2018 IPR029056 Ribokinase-like MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 SUPERFAMILY SSF51391 328 519 1.01E-61 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 Pfam PF08543 Phosphomethylpyrimidine kinase 23 256 1.0E-48 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 SUPERFAMILY SSF53613 13 254 3.76E-49 T 13-10-2018 IPR029056 Ribokinase-like MADE_1000715 143eb6a0ce7489cbd4abcd549705c878 526 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 337 516 1.2E-52 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 MADE_000001022880 7bc05bbc55c888f9c45475078ee2dadb 496 Gene3D G3DSA:3.40.605.10 22 458 4.1E-155 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_000001022880 7bc05bbc55c888f9c45475078ee2dadb 496 Pfam PF00171 Aldehyde dehydrogenase family 18 477 2.0E-137 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_000001022880 7bc05bbc55c888f9c45475078ee2dadb 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MADE_000001022880 7bc05bbc55c888f9c45475078ee2dadb 496 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 481 1.4E-207 T 13-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 MADE_000001022880 7bc05bbc55c888f9c45475078ee2dadb 496 SUPERFAMILY SSF53720 2 482 3.4E-145 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_000001022880 7bc05bbc55c888f9c45475078ee2dadb 496 Gene3D G3DSA:3.40.309.10 248 450 4.1E-155 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_000001022225 a0ad70aa06f3934c57d79d913d767591 270 SUPERFAMILY SSF51366 1 256 1.81E-68 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MADE_000001022225 a0ad70aa06f3934c57d79d913d767591 270 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 42.763 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MADE_000001022225 a0ad70aa06f3934c57d79d913d767591 270 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 6.9E-107 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 MADE_000001022225 a0ad70aa06f3934c57d79d913d767591 270 Pfam PF00977 Histidine biosynthesis protein 5 239 2.2E-75 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MADE_000001022225 a0ad70aa06f3934c57d79d913d767591 270 Gene3D G3DSA:3.20.20.70 1 266 7.0E-90 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1007110 3b1879b2b5e7b6749b79ccc00eca6588 130 Pfam PF11528 Protein of unknown function (DUF3224) 4 125 1.4E-32 T 13-10-2018 IPR021607 Protein of unknown function DUF3224 MADE_1007110 3b1879b2b5e7b6749b79ccc00eca6588 130 Gene3D G3DSA:2.40.350.10 1 130 6.2E-40 T 13-10-2018 IPR023159 SO1590-like superfamily MADE_1007110 3b1879b2b5e7b6749b79ccc00eca6588 130 SUPERFAMILY SSF159238 1 126 4.05E-36 T 13-10-2018 IPR023159 SO1590-like superfamily MADE_1008670 44f10a4d72f0d4800ff9e17196732204 206 Gene3D G3DSA:3.90.950.10 2 199 2.1E-52 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_1008670 44f10a4d72f0d4800ff9e17196732204 206 PIRSF PIRSF006305 2 198 1.1E-38 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1008670 44f10a4d72f0d4800ff9e17196732204 206 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 192 5.5E-46 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1008670 44f10a4d72f0d4800ff9e17196732204 206 Pfam PF02545 Maf-like protein 3 193 1.1E-43 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1008670 44f10a4d72f0d4800ff9e17196732204 206 SUPERFAMILY SSF52972 3 192 1.9E-50 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_1008670 44f10a4d72f0d4800ff9e17196732204 206 Hamap MF_00528 Septum formation protein Maf [maf]. 3 198 24.355 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 MADE_1010190 6f1ee229ec3c7697d98c7abd9222aa2f 585 Pfam PF11949 Protein of unknown function (DUF3466) 6 582 5.6E-84 T 13-10-2018 IPR022562 Protein of unknown function DUF3466 MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 SUPERFAMILY SSF53383 1 358 2.12E-113 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 Pfam PF00266 Aminotransferase class-V 4 348 2.8E-55 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 188 207 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 PIRSF PIRSF000525 1 361 3.3E-146 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 360 50.027 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 358 5.8E-152 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 Gene3D G3DSA:3.40.640.10 16 258 2.5E-85 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_000001022120 ba16626a19f1c30d00f9e7e453604027 361 Gene3D G3DSA:3.90.1150.10 259 361 1.1E-40 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 Pfam PF00072 Response regulator receiver domain 21 107 4.6E-5 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 SUPERFAMILY SSF52172 18 153 3.27E-10 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 Gene3D G3DSA:3.40.50.2300 10 161 1.3E-12 T 13-10-2018 MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 Gene3D G3DSA:1.10.3210.10 305 506 2.7E-69 T 13-10-2018 MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 SUPERFAMILY SSF109604 320 494 4.08E-37 T 13-10-2018 MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 SMART SM00471 327 464 1.6E-7 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 Pfam PF13487 HD domain 382 446 2.6E-17 T 13-10-2018 MADE_1011840 a7dedae7b55d8dbc5425acd8aa89c450 509 Pfam PF11849 Domain of unknown function (DUF3369) 141 308 2.2E-37 T 13-10-2018 IPR021800 Domain of unknown function DUF3369 MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 PIRSF PIRSF000089 1 308 8.6E-108 T 13-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 SUPERFAMILY SSF52402 2 183 1.4E-58 T 13-10-2018 MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 SUPERFAMILY SSF52467 188 306 2.09E-48 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 Gene3D G3DSA:3.40.50.1220 183 308 2.6E-58 T 13-10-2018 MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 SMART SM00893 3 181 2.8E-53 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 271 2.9E-36 T 13-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 Gene3D G3DSA:3.40.50.620 2 182 1.1E-57 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 252 278 - T 13-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 MADE_1013770 9f2d637991dda51fcb49d6a7e39bcaf6 308 Pfam PF01012 Electron transfer flavoprotein domain 3 168 1.2E-38 T 13-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 MADE_1019550 110fab28026ce640cd4d41568817b9ff 196 SUPERFAMILY SSF88946 6 84 6.67E-9 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1019550 110fab28026ce640cd4d41568817b9ff 196 Gene3D G3DSA:1.10.10.10 108 165 6.8E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1019550 110fab28026ce640cd4d41568817b9ff 196 Pfam PF04542 Sigma-70 region 2 22 74 7.5E-8 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1019550 110fab28026ce640cd4d41568817b9ff 196 SUPERFAMILY SSF88659 107 163 2.4E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1019550 110fab28026ce640cd4d41568817b9ff 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 162 2.3E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1019550 110fab28026ce640cd4d41568817b9ff 196 Gene3D G3DSA:1.10.1740.10 4 107 9.5E-7 T 13-10-2018 MADE_1019550 110fab28026ce640cd4d41568817b9ff 196 Pfam PF08281 Sigma-70, region 4 115 162 7.0E-14 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1007285 b8a1e9ae6520a563da27e693eae3c833 323 SUPERFAMILY SSF81345 40 318 8.76E-62 T 13-10-2018 IPR037294 ABC transporter, BtuC-like MADE_1007285 b8a1e9ae6520a563da27e693eae3c833 323 Pfam PF01032 FecCD transport family 37 318 3.7E-70 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MADE_1007285 b8a1e9ae6520a563da27e693eae3c833 323 Gene3D G3DSA:1.10.3470.10 30 322 4.9E-77 T 13-10-2018 IPR037294 ABC transporter, BtuC-like MADE_000001023090 28e176772e423b8343e3c23264a0818c 568 Gene3D G3DSA:1.20.1730.10 348 560 2.0E-26 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_000001023090 28e176772e423b8343e3c23264a0818c 568 Gene3D G3DSA:1.20.1730.10 8 330 8.9E-39 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_000001023090 28e176772e423b8343e3c23264a0818c 568 Pfam PF00474 Sodium:solute symporter family 375 490 4.4E-15 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_000001023090 28e176772e423b8343e3c23264a0818c 568 Pfam PF00474 Sodium:solute symporter family 33 304 1.7E-36 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_000001023090 28e176772e423b8343e3c23264a0818c 568 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 8 559 4.1E-263 T 13-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily MADE_1005290 e12840f5c6265474dbc42c13371eb7bb 280 SUPERFAMILY SSF56281 1 279 6.94E-38 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1005290 e12840f5c6265474dbc42c13371eb7bb 280 Pfam PF12706 Beta-lactamase superfamily domain 39 236 3.9E-16 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1005290 e12840f5c6265474dbc42c13371eb7bb 280 Gene3D G3DSA:3.60.15.10 2 280 2.0E-38 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1004175 76d3176c531c112c33ad5c137e3d8a8e 147 Gene3D G3DSA:3.40.930.10 1 147 3.3E-47 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MADE_1004175 76d3176c531c112c33ad5c137e3d8a8e 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 10 146 4.4E-34 T 13-10-2018 IPR002178 PTS EIIA type-2 domain MADE_1004175 76d3176c531c112c33ad5c137e3d8a8e 147 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 6 142 5.5E-43 T 13-10-2018 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 MADE_1004175 76d3176c531c112c33ad5c137e3d8a8e 147 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 13-10-2018 IPR002178 PTS EIIA type-2 domain MADE_1004175 76d3176c531c112c33ad5c137e3d8a8e 147 SUPERFAMILY SSF55804 1 146 7.72E-35 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 MADE_1000235 ff739e17314fb7f43a14c52eee40b69c 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 6.4E-69 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 MADE_1000235 ff739e17314fb7f43a14c52eee40b69c 225 Gene3D G3DSA:3.40.140.10 101 224 1.1E-40 T 13-10-2018 MADE_1000235 ff739e17314fb7f43a14c52eee40b69c 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site MADE_1000235 ff739e17314fb7f43a14c52eee40b69c 225 Pfam PF04002 RadC-like JAB domain 104 222 3.1E-41 T 13-10-2018 IPR025657 RadC-like JAB domain MADE_1000235 ff739e17314fb7f43a14c52eee40b69c 225 SUPERFAMILY SSF102712 119 192 5.62E-5 T 13-10-2018 MADE_1000235 ff739e17314fb7f43a14c52eee40b69c 225 SUPERFAMILY SSF47781 17 87 8.45E-8 T 13-10-2018 IPR010994 RuvA domain 2-like MADE_1005520 e3ee06a277f8f365913ed7a64faff6a1 115 Pfam PF02411 MerT mercuric transport protein 4 115 2.2E-48 T 13-10-2018 IPR003457 Mercuric transport protein MerT GO:0015097|GO:0015694|GO:0016020 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 SUPERFAMILY SSF56176 38 194 2.9E-37 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 Gene3D G3DSA:3.90.78.10 217 359 1.6E-36 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 Gene3D G3DSA:3.30.465.10 69 216 1.1E-53 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 Pfam PF01565 FAD binding domain 40 147 2.7E-17 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 360 66.016 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 4 353 3.3E-70 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 SUPERFAMILY SSF56194 200 354 2.88E-35 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 Gene3D G3DSA:3.30.43.10 3 68 1.4E-12 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MADE_1017380 ead0fe539feaaa8699342c18a6d7aa7b 360 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 204 351 4.5E-30 T 13-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 Gene3D G3DSA:1.10.287.470 180 309 4.4E-16 T 13-10-2018 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 95 115 1.3E-45 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 322 343 1.3E-45 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 434 454 1.3E-45 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 53 76 1.3E-45 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 355 379 1.3E-45 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 379 402 1.3E-45 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 419 434 1.3E-45 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 SUPERFAMILY SSF111369 92 154 3.79E-7 T 13-10-2018 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 Pfam PF13533 Biotin-lipoyl like 91 124 1.1E-7 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 Gene3D G3DSA:2.40.30.170 347 432 4.4E-16 T 13-10-2018 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 Pfam PF13437 HlyD family secretion protein 310 422 1.7E-17 T 13-10-2018 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 Gene3D G3DSA:2.40.50.100 86 155 1.2E-7 T 13-10-2018 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 45 455 5.3E-113 T 13-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 Gene3D G3DSA:2.40.50.100 175 346 4.4E-16 T 13-10-2018 MADE_1005650 b81d7c9568b9fc2e7b06f94ceae91dc3 455 ProSitePatterns PS00543 HlyD family secretion proteins signature. 419 441 - T 13-10-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 MADE_1000565 43f451bdb690908054b1f440674eeba8 704 Pfam PF13476 AAA domain 5 266 2.3E-10 T 13-10-2018 IPR038729 Rad50/SbcC-type AAA domain MADE_1000565 43f451bdb690908054b1f440674eeba8 704 SUPERFAMILY SSF52540 1 654 2.48E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000565 43f451bdb690908054b1f440674eeba8 704 Gene3D G3DSA:3.40.50.300 364 678 2.3E-5 T 13-10-2018 MADE_1000565 43f451bdb690908054b1f440674eeba8 704 Gene3D G3DSA:3.40.50.300 1 304 1.4E-22 T 13-10-2018 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 Gene3D G3DSA:2.40.50.100 66 187 6.6E-6 T 13-10-2018 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 Gene3D G3DSA:1.10.287.470 224 287 8.7E-14 T 13-10-2018 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 357 380 6.5E-53 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 333 357 6.5E-53 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 400 415 6.5E-53 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 27 50 6.5E-53 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 415 435 6.5E-53 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 69 89 6.5E-53 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 300 321 6.5E-53 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 Pfam PF13533 Biotin-lipoyl like 65 93 1.1E-6 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 22 436 3.4E-118 T 13-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 Gene3D G3DSA:2.40.50.100 219 324 8.7E-14 T 13-10-2018 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 Gene3D G3DSA:2.40.30.170 325 412 8.7E-14 T 13-10-2018 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 Gene3D G3DSA:1.10.287.470 91 161 6.6E-6 T 13-10-2018 MADE_1006965 42837dcf5a52d2347752ecefbb012424 436 Pfam PF13437 HlyD family secretion protein 287 391 4.9E-15 T 13-10-2018 MADE_1005915 de658ff4f5dfe7abac3ad50d5bb0bac8 444 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 25 436 2.7E-194 T 13-10-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1005915 de658ff4f5dfe7abac3ad50d5bb0bac8 444 Gene3D G3DSA:3.40.50.12240 17 440 8.7E-153 T 13-10-2018 MADE_1005915 de658ff4f5dfe7abac3ad50d5bb0bac8 444 SMART SM00382 159 342 3.0E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005915 de658ff4f5dfe7abac3ad50d5bb0bac8 444 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 349 358 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1005915 de658ff4f5dfe7abac3ad50d5bb0bac8 444 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 147 358 3.9E-73 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1005915 de658ff4f5dfe7abac3ad50d5bb0bac8 444 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 10 437 4.2E-172 T 13-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1005915 de658ff4f5dfe7abac3ad50d5bb0bac8 444 SUPERFAMILY SSF52540 95 364 1.23E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007005 48def8a7d239f8388ecb52b3e36bd6b4 353 Gene3D G3DSA:3.40.50.1820 19 187 4.4E-14 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007005 48def8a7d239f8388ecb52b3e36bd6b4 353 SUPERFAMILY SSF53474 34 341 4.17E-77 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007005 48def8a7d239f8388ecb52b3e36bd6b4 353 Pfam PF00326 Prolyl oligopeptidase family 39 187 1.9E-5 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MADE_1007005 48def8a7d239f8388ecb52b3e36bd6b4 353 Gene3D G3DSA:3.40.50.1820 217 346 3.1E-9 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007005 48def8a7d239f8388ecb52b3e36bd6b4 353 Pfam PF10503 Esterase PHB depolymerase 242 328 5.6E-7 T 13-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 MADE_000001023150 50efdab6cf6c493259f5eec08264185c 350 Gene3D G3DSA:3.20.20.100 1 349 2.8E-107 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_000001023150 50efdab6cf6c493259f5eec08264185c 350 SUPERFAMILY SSF51430 1 348 4.58E-91 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_000001023150 50efdab6cf6c493259f5eec08264185c 350 Pfam PF00248 Aldo/keto reductase family 16 341 3.5E-62 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 SMART SM00650 24 200 7.9E-85 T 13-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 Gene3D G3DSA:1.10.8.100 203 269 1.8E-22 T 13-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 40 67 - T 13-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 9 265 6.7E-89 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 SUPERFAMILY SSF53335 7 266 2.04E-75 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 8 267 55.876 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 Gene3D G3DSA:3.40.50.150 2 201 1.8E-64 T 13-10-2018 MADE_1003980 2b3e7d134cd0fc399b153fe5d3ad87ea 275 Pfam PF00398 Ribosomal RNA adenine dimethylase 8 265 5.9E-77 T 13-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm MADE_1012900 d21d61b1b92e4acf7715bfc37aea94fd 253 Pfam PF00005 ABC transporter 18 172 1.6E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1012900 d21d61b1b92e4acf7715bfc37aea94fd 253 SUPERFAMILY SSF52540 2 229 2.66E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012900 d21d61b1b92e4acf7715bfc37aea94fd 253 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 242 1.9E-107 T 13-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 MADE_1012900 d21d61b1b92e4acf7715bfc37aea94fd 253 SMART SM00382 26 229 6.4E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012900 d21d61b1b92e4acf7715bfc37aea94fd 253 Gene3D G3DSA:3.40.50.300 1 247 1.9E-59 T 13-10-2018 MADE_1003455 664d385eae61160e892eb9e5650a8f51 267 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MADE_1003455 664d385eae61160e892eb9e5650a8f51 267 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 5 262 1.2E-81 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MADE_1003455 664d385eae61160e892eb9e5650a8f51 267 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 11 261 19.896 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MADE_1003455 664d385eae61160e892eb9e5650a8f51 267 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 14 255 3.8E-81 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 Pfam PF13180 PDZ domain 288 357 1.6E-17 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 Pfam PF13365 Trypsin-like peptidase domain 92 227 2.3E-33 T 13-10-2018 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 Gene3D G3DSA:2.40.10.120 39 260 1.5E-87 T 13-10-2018 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 PRINTS PR00834 HtrA/DegQ protease family signature 102 114 1.3E-57 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 PRINTS PR00834 HtrA/DegQ protease family signature 163 187 1.3E-57 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 PRINTS PR00834 HtrA/DegQ protease family signature 198 215 1.3E-57 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 PRINTS PR00834 HtrA/DegQ protease family signature 123 143 1.3E-57 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 PRINTS PR00834 HtrA/DegQ protease family signature 220 237 1.3E-57 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 PRINTS PR00834 HtrA/DegQ protease family signature 306 318 1.3E-57 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 SUPERFAMILY SSF50156 387 454 1.31E-13 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 SUPERFAMILY SSF50494 40 257 2.16E-67 T 13-10-2018 IPR009003 Peptidase S1, PA clan MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 Gene3D G3DSA:2.30.42.10 264 363 9.0E-27 T 13-10-2018 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 375 442 1.1E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 41 452 8.7E-156 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 SUPERFAMILY SSF50156 224 349 8.15E-25 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 Gene3D G3DSA:2.30.42.10 364 455 3.8E-25 T 13-10-2018 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 SMART SM00228 373 446 3.3E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1004260 e24ef8481ae10e35f789bb75f3100229 455 SMART SM00228 266 348 4.6E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 Gene3D G3DSA:3.30.70.1450 645 718 4.1E-10 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 Pfam PF02080 TrkA-C domain 649 716 3.4E-10 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 SUPERFAMILY SSF116726 642 714 3.4E-11 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 Pfam PF02254 TrkA-N domain 472 585 9.4E-23 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 SUPERFAMILY SSF51735 468 611 5.42E-31 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 Gene3D G3DSA:3.40.50.720 467 627 1.8E-34 T 13-10-2018 MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 Pfam PF00999 Sodium/hydrogen exchanger family 73 438 9.3E-64 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MADE_1005410 6497c7d6308fd3a77ac47d2702f9f079 720 Gene3D G3DSA:1.20.1530.20 67 452 3.2E-83 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 Gene3D G3DSA:3.50.50.60 8 344 8.3E-79 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 8 341 7.8E-87 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 Pfam PF01494 FAD binding domain 7 338 4.9E-21 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 Gene3D G3DSA:3.30.9.50 94 289 8.3E-79 T 13-10-2018 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 314 327 - T 13-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 1.6E-10 T 13-10-2018 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 315 1.6E-10 T 13-10-2018 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 331 1.6E-10 T 13-10-2018 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 1.6E-10 T 13-10-2018 MADE_1014485 723021d2e36042bf2486a70b5d20c3fe 447 SUPERFAMILY SSF51905 7 426 3.03E-37 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:3.30.2090.10 714 802 7.2E-268 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 SUPERFAMILY SSF82866 800 1036 3.53E-45 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1037 0.0 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Pfam PF00873 AcrB/AcrD/AcrF family 6 1032 9.9E-238 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 6.6E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 6.6E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 6.6E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 6.6E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 6.6E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 6.6E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 6.6E-31 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:3.30.70.1320 135 330 7.2E-268 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:3.30.70.1430 42 810 7.2E-268 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:1.20.1640.10 510 1030 7.2E-268 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:3.30.70.1440 663 860 7.2E-268 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 SUPERFAMILY SSF82866 294 499 3.01E-40 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 SUPERFAMILY SSF82714 716 799 5.23E-19 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 SUPERFAMILY SSF82693 46 128 1.02E-20 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:3.30.70.1430 560 662 7.2E-268 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:1.20.1640.10 12 509 7.2E-268 T 13-10-2018 MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 Gene3D G3DSA:3.30.2090.10 181 272 7.2E-268 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 SUPERFAMILY SSF82714 185 269 4.05E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001555 6a0c35957777a12558c6cdd61df5118d 1045 SUPERFAMILY SSF82693 137 328 4.19E-23 T 13-10-2018 MADE_1018185 2d8295f50428a4b5cb01ddd31c497cea 434 SUPERFAMILY SSF52172 11 177 1.57E-32 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1018185 2d8295f50428a4b5cb01ddd31c497cea 434 Gene3D G3DSA:1.10.3210.10 172 364 6.2E-23 T 13-10-2018 MADE_1018185 2d8295f50428a4b5cb01ddd31c497cea 434 Gene3D G3DSA:3.40.50.2300 2 149 1.4E-31 T 13-10-2018 MADE_1018185 2d8295f50428a4b5cb01ddd31c497cea 434 Pfam PF13487 HD domain 250 310 7.4E-7 T 13-10-2018 MADE_1018185 2d8295f50428a4b5cb01ddd31c497cea 434 Pfam PF00072 Response regulator receiver domain 13 123 2.3E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1018185 2d8295f50428a4b5cb01ddd31c497cea 434 SMART SM00448 11 123 2.0E-19 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1009715 2a01ea9b3129e2a215bc433f5a049508 275 Gene3D G3DSA:2.40.50.40 168 237 4.1E-13 T 13-10-2018 MADE_1009715 2a01ea9b3129e2a215bc433f5a049508 275 SMART SM00448 6 118 3.2E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1009715 2a01ea9b3129e2a215bc433f5a049508 275 Pfam PF00072 Response regulator receiver domain 9 118 1.6E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1009715 2a01ea9b3129e2a215bc433f5a049508 275 Pfam PF04397 LytTr DNA-binding domain 178 273 1.1E-22 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MADE_1009715 2a01ea9b3129e2a215bc433f5a049508 275 SUPERFAMILY SSF52172 8 138 7.68E-34 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1009715 2a01ea9b3129e2a215bc433f5a049508 275 Gene3D G3DSA:3.40.50.2300 1 139 4.4E-36 T 13-10-2018 MADE_1009715 2a01ea9b3129e2a215bc433f5a049508 275 SMART SM00850 177 274 6.2E-32 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 Gene3D G3DSA:3.60.20.40 373 563 1.2E-68 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 SUPERFAMILY SSF56235 29 563 2.76E-184 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 250 266 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 428 443 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 452 469 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 279 298 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 397 415 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 63 88 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 134 152 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 152 171 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 373 391 8.0E-48 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 Pfam PF01019 Gamma-glutamyltranspeptidase 56 558 5.3E-166 T 13-10-2018 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 41 555 1.3E-126 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 MADE_1002430 b53b6206d81238765ddd7c26354dd1cc 563 Gene3D G3DSA:1.10.246.130 266 372 2.4E-38 T 13-10-2018 MADE_1005215 e70426faf0e2240a5646a977115a665d 372 SUPERFAMILY SSF56014 265 354 3.78E-14 T 13-10-2018 MADE_1005215 e70426faf0e2240a5646a977115a665d 372 Gene3D G3DSA:3.30.413.10 262 361 2.1E-25 T 13-10-2018 MADE_1005215 e70426faf0e2240a5646a977115a665d 372 Pfam PF04551 GcpE protein 13 354 1.5E-135 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MADE_1005215 e70426faf0e2240a5646a977115a665d 372 PIRSF PIRSF004640 1 364 1.5E-148 T 13-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MADE_1005215 e70426faf0e2240a5646a977115a665d 372 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 358 35.483 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MADE_1005215 e70426faf0e2240a5646a977115a665d 372 SUPERFAMILY SSF51604 40 139 8.83E-8 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily MADE_1005215 e70426faf0e2240a5646a977115a665d 372 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 352 5.1E-131 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 MADE_1005215 e70426faf0e2240a5646a977115a665d 372 Gene3D G3DSA:3.20.20.20 1 261 3.3E-108 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 MADE_1019410 5fd133970eb93e9f5e935f247957bf61 400 Pfam PF05940 NnrS protein 15 394 1.0E-106 T 13-10-2018 IPR010266 NnrS MADE_000001023400 de18b866810be965e0d757f228d6706f 271 SUPERFAMILY SSF82861 22 106 6.02E-17 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MADE_000001023400 de18b866810be965e0d757f228d6706f 271 Gene3D G3DSA:2.30.30.60 123 171 5.9E-10 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_000001023400 de18b866810be965e0d757f228d6706f 271 SUPERFAMILY SSF50182 108 171 5.23E-13 T 13-10-2018 IPR010920 LSM domain superfamily MADE_000001023400 de18b866810be965e0d757f228d6706f 271 SUPERFAMILY SSF82689 174 269 2.62E-28 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_000001023400 de18b866810be965e0d757f228d6706f 271 Gene3D G3DSA:3.30.70.100 173 264 2.6E-23 T 13-10-2018 MADE_000001023400 de18b866810be965e0d757f228d6706f 271 Pfam PF05552 Conserved TM helix 13 58 8.3E-12 T 13-10-2018 IPR008910 Conserved TM helix MADE_000001023400 de18b866810be965e0d757f228d6706f 271 Pfam PF00924 Mechanosensitive ion channel 66 260 2.3E-41 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1008045 4a36096e37a995d56fc7ea457cf727b6 187 SUPERFAMILY SSF48452 6 182 1.06E-63 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008045 4a36096e37a995d56fc7ea457cf727b6 187 Gene3D G3DSA:1.25.40.10 87 186 2.7E-31 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008045 4a36096e37a995d56fc7ea457cf727b6 187 Pfam PF06041 Bacterial protein of unknown function (DUF924) 14 182 1.1E-58 T 13-10-2018 IPR010323 Protein of unknown function DUF924 MADE_1008045 4a36096e37a995d56fc7ea457cf727b6 187 Gene3D G3DSA:1.20.58.320 5 86 8.9E-26 T 13-10-2018 MADE_1008005 4e6b2e721c7bbe18a97d480a4c680e9d 517 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 356 376 - T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MADE_1008005 4e6b2e721c7bbe18a97d480a4c680e9d 517 Pfam PF00860 Permease family 22 408 1.1E-79 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MADE_1008005 4e6b2e721c7bbe18a97d480a4c680e9d 517 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 18 437 1.1E-99 T 13-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 MADE_1015205 dbadf758c98f719cdbacc10b6e16f8f1 256 Pfam PF07277 SapC 8 224 1.4E-66 T 13-10-2018 IPR010836 SapC MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 Gene3D G3DSA:3.90.1310.10 65 250 1.8E-49 T 13-10-2018 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 612 3.1E-70 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 SUPERFAMILY SSF56519 58 253 1.05E-51 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 240 4.9E-45 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 4 619 50.923 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 Gene3D G3DSA:3.30.1390.30 86 161 1.8E-49 T 13-10-2018 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 20 616 1.8E-230 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 Gene3D G3DSA:3.40.710.10 255 621 1.8E-91 T 13-10-2018 MADE_000001021815 52465d0ae1be8a179da12855ed10ece5 637 SUPERFAMILY SSF56601 255 616 1.94E-94 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_000001022815 02b8002c79c0dffbdefd5ba580253665 338 Gene3D G3DSA:3.40.50.1100 53 149 3.3E-93 T 13-10-2018 MADE_000001022815 02b8002c79c0dffbdefd5ba580253665 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 307 4.4E-68 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MADE_000001022815 02b8002c79c0dffbdefd5ba580253665 338 Gene3D G3DSA:3.40.50.1100 15 311 3.3E-93 T 13-10-2018 MADE_000001022815 02b8002c79c0dffbdefd5ba580253665 338 SUPERFAMILY SSF53686 6 311 1.07E-78 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MADE_1000500 cb4356e814009ea1e0db4c308249f7bf 339 Gene3D G3DSA:2.40.30.170 200 263 4.6E-13 T 13-10-2018 MADE_1000500 cb4356e814009ea1e0db4c308249f7bf 339 Gene3D G3DSA:2.40.420.20 264 310 4.6E-13 T 13-10-2018 MADE_1000500 cb4356e814009ea1e0db4c308249f7bf 339 Gene3D G3DSA:1.10.287.470 92 163 4.6E-13 T 13-10-2018 MADE_1000500 cb4356e814009ea1e0db4c308249f7bf 339 Gene3D G3DSA:2.40.50.100 72 199 4.6E-13 T 13-10-2018 MADE_1014050 537023926cc36d2850df80d263f9fd50 200 Gene3D G3DSA:3.30.160.670 34 195 2.2E-12 T 13-10-2018 MADE_1014050 537023926cc36d2850df80d263f9fd50 200 Pfam PF13590 Domain of unknown function (DUF4136) 44 193 1.3E-11 T 13-10-2018 IPR025411 Domain of unknown function DUF4136 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 SUPERFAMILY SSF88659 165 239 6.98E-17 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 3 326 39.558 T 13-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Gene3D G3DSA:1.10.10.10 243 317 5.1E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1003355 74db8d070226058fc31f92ca420ea681 330 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 46 326 2.4E-139 T 13-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 89 315 5.0E-37 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 PRINTS PR00046 Major sigma-70 factor signature 264 276 9.6E-28 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 PRINTS PR00046 Major sigma-70 factor signature 285 300 9.6E-28 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 PRINTS PR00046 Major sigma-70 factor signature 300 311 9.6E-28 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 PRINTS PR00046 Major sigma-70 factor signature 116 129 9.6E-28 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 PRINTS PR00046 Major sigma-70 factor signature 140 148 9.6E-28 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Pfam PF04545 Sigma-70, region 4 260 313 5.4E-18 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Pfam PF04539 Sigma-70 region 3 172 247 1.2E-23 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Pfam PF04542 Sigma-70 region 2 93 161 2.0E-20 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 116 129 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Gene3D G3DSA:1.10.601.10 79 164 1.1E-45 T 13-10-2018 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 SUPERFAMILY SSF88946 54 162 3.14E-44 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Gene3D G3DSA:1.10.10.10 165 240 1.1E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1003355 74db8d070226058fc31f92ca420ea681 330 Pfam PF00140 Sigma-70 factor, region 1.2 54 84 5.6E-10 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 285 311 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 MADE_1003355 74db8d070226058fc31f92ca420ea681 330 SUPERFAMILY SSF88659 222 320 7.29E-26 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 Gene3D G3DSA:3.20.20.300 55 416 1.4E-142 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 SUPERFAMILY SSF52279 434 641 4.97E-48 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 Gene3D G3DSA:2.60.120.430 657 850 4.2E-23 T 13-10-2018 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 70 393 4.1E-86 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 PRINTS PR00133 Glycosyl hydrolase family 3 signature 160 179 1.5E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 PRINTS PR00133 Glycosyl hydrolase family 3 signature 136 152 1.5E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 PRINTS PR00133 Glycosyl hydrolase family 3 signature 206 222 1.5E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 PRINTS PR00133 Glycosyl hydrolase family 3 signature 316 334 1.5E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 PRINTS PR00133 Glycosyl hydrolase family 3 signature 246 262 1.5E-21 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 SUPERFAMILY SSF51445 53 433 7.37E-114 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 Gene3D G3DSA:3.40.50.1700 419 644 1.6E-71 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 SUPERFAMILY SSF49785 700 838 4.17E-5 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1019030 2c7e63d053a6cd2b1cfc3552eb090a99 850 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 434 639 4.6E-38 T 13-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Pfam PF07495 Y_Y_Y domain 668 728 8.7E-12 T 13-10-2018 IPR011123 Two component regulator three Y MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 788 950 1.5E-44 T 13-10-2018 IPR000160 GGDEF domain MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Gene3D G3DSA:2.130.10.10 10 112 1.9E-10 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 SMART SM00267 780 951 1.1E-54 T 13-10-2018 IPR000160 GGDEF domain MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Pfam PF00990 Diguanylate cyclase, GGDEF domain 791 947 1.0E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 SUPERFAMILY SSF63829 90 342 6.98E-10 T 13-10-2018 MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 SUPERFAMILY SSF63829 377 553 5.1E-7 T 13-10-2018 MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Gene3D G3DSA:2.60.40.10 619 736 3.4E-19 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 SUPERFAMILY SSF55073 796 951 1.65E-44 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Gene3D G3DSA:2.130.10.10 121 351 9.9E-38 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Gene3D G3DSA:2.130.10.10 355 618 2.6E-35 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Gene3D G3DSA:3.30.70.270 777 952 1.6E-53 T 13-10-2018 MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Pfam PF07494 Two component regulator propeller 277 300 0.0098 T 13-10-2018 IPR011110 Two component regulator propeller MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Pfam PF07494 Two component regulator propeller 35 57 2.2E-4 T 13-10-2018 IPR011110 Two component regulator propeller MADE_1006425 c7e6d9bd764920ee0a7e8b97bd93d589 952 Pfam PF07494 Two component regulator propeller 235 258 0.012 T 13-10-2018 IPR011110 Two component regulator propeller MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 PRINTS PR00069 Aldo-keto reductase signature 82 100 3.0E-46 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 PRINTS PR00069 Aldo-keto reductase signature 26 50 3.0E-46 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 PRINTS PR00069 Aldo-keto reductase signature 187 211 3.0E-46 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 PRINTS PR00069 Aldo-keto reductase signature 150 179 3.0E-46 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 PRINTS PR00069 Aldo-keto reductase signature 115 132 3.0E-46 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 115 132 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 Pfam PF00248 Aldo/keto reductase family 7 251 6.3E-47 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 SUPERFAMILY SSF51430 3 262 3.8E-78 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 30 47 - T 13-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 PIRSF PIRSF000097 1 266 1.6E-62 T 13-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 MADE_1006930 bf044cc87e1432e3c5654be4bc73967a 267 Gene3D G3DSA:3.20.20.100 1 267 2.0E-86 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 Gene3D G3DSA:3.30.428.10 176 350 1.2E-67 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 SUPERFAMILY SSF54197 180 345 9.7E-47 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 Gene3D G3DSA:3.30.428.10 46 175 5.1E-54 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 3 347 6.9E-166 T 13-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 SUPERFAMILY SSF54197 5 176 1.02E-68 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 151 168 - T 13-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 PIRSF PIRSF000808 2 340 1.2E-117 T 13-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 5 176 4.2E-70 T 13-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MADE_1001135 9a295ac4315ba8e175870372a472fa5b 351 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 183 346 2.7E-63 T 13-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 930 21.335 T 13-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 Gene3D G3DSA:1.10.730.20 643 930 5.3E-87 T 13-10-2018 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 Pfam PF08264 Anticodon-binding domain of tRNA 687 843 2.4E-27 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 SUPERFAMILY SSF50677 203 407 2.93E-56 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 844 8.4E-290 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 Gene3D G3DSA:3.40.50.620 25 632 1.3E-240 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 SUPERFAMILY SSF47323 655 930 5.98E-73 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 643 1.4E-212 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 SUPERFAMILY SSF52374 4 651 1.25E-139 T 13-10-2018 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 Pfam PF06827 Zinc finger found in FPG and IleRS 899 927 3.7E-8 T 13-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 405 420 2.7E-33 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 530 543 2.7E-33 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 2.7E-33 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 564 573 2.7E-33 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 241 264 2.7E-33 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 MADE_000001022280 757f75d4ef03eb8bf1ed62c3e1f1dc5d 939 Gene3D G3DSA:3.90.740.10 195 412 1.3E-240 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 Gene3D G3DSA:3.30.160.20 1 73 1.4E-32 T 13-10-2018 MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 35.131 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 12 74 2.2E-29 T 13-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 163 3.7E-69 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 Gene3D G3DSA:3.30.230.10 74 166 9.6E-38 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.2E-30 T 13-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 SUPERFAMILY SSF54768 8 76 4.29E-24 T 13-10-2018 MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 13-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site MADE_1013975 926c26ffd6cf1f5a836435192fc10100 166 SUPERFAMILY SSF54211 79 158 1.77E-27 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 SMART SM01097 71 201 1.8E-91 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 SUPERFAMILY SSF52021 72 207 1.2E-56 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 Gene3D G3DSA:3.50.30.20 70 219 1.8E-60 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 SUPERFAMILY SSF52317 222 443 2.37E-61 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 73 440 4.1E-147 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 Gene3D G3DSA:3.40.50.880 220 443 3.5E-74 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 Pfam PF00117 Glutamine amidotransferase class-I 262 437 1.2E-49 T 13-10-2018 IPR017926 Glutamine amidotransferase MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 273 1.9E-40 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 298 312 1.9E-40 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 329 345 1.9E-40 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 371 382 1.9E-40 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 346 363 1.9E-40 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 73 200 2.6E-53 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00096 Glutamine amidotransferase superfamily signature 329 340 1.5E-10 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00096 Glutamine amidotransferase superfamily signature 414 427 1.5E-10 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 PRINTS PR00096 Glutamine amidotransferase superfamily signature 301 310 1.5E-10 T 13-10-2018 MADE_1007090 8b442b3441d144512703b4acbdc3f27d 444 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 71 443 48.852 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 MADE_1015535 ecdaa99eedebc4ad3f620935b427e3ea 226 SMART SM00862 146 221 3.3E-29 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1015535 ecdaa99eedebc4ad3f620935b427e3ea 226 Gene3D G3DSA:1.10.10.10 118 224 2.4E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015535 ecdaa99eedebc4ad3f620935b427e3ea 226 Pfam PF00072 Response regulator receiver domain 3 113 5.1E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015535 ecdaa99eedebc4ad3f620935b427e3ea 226 Gene3D G3DSA:3.40.50.2300 1 117 3.5E-34 T 13-10-2018 MADE_1015535 ecdaa99eedebc4ad3f620935b427e3ea 226 SMART SM00448 1 112 3.4E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015535 ecdaa99eedebc4ad3f620935b427e3ea 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.1E-28 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1015535 ecdaa99eedebc4ad3f620935b427e3ea 226 SUPERFAMILY SSF52172 1 181 2.61E-35 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1009080 eee73bf99b1db0885346298fba18eed7 212 SUPERFAMILY SSF52540 5 209 9.35E-49 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009080 eee73bf99b1db0885346298fba18eed7 212 SMART SM00382 26 212 3.7E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1009080 eee73bf99b1db0885346298fba18eed7 212 Gene3D G3DSA:3.40.50.300 3 211 3.3E-48 T 13-10-2018 MADE_1009080 eee73bf99b1db0885346298fba18eed7 212 Pfam PF00005 ABC transporter 18 163 1.3E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1009080 eee73bf99b1db0885346298fba18eed7 212 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1013530 0d76bed156524a4545924728518bbe62 162 Pfam PF01967 MoaC family 15 150 2.3E-52 T 13-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1013530 0d76bed156524a4545924728518bbe62 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 151 2.6E-60 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1013530 0d76bed156524a4545924728518bbe62 162 Gene3D G3DSA:3.30.70.640 1 161 7.5E-66 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1013530 0d76bed156524a4545924728518bbe62 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 158 33.532 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1013530 0d76bed156524a4545924728518bbe62 162 SUPERFAMILY SSF55040 11 155 1.01E-57 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_000001020780 5b1e36a1d1c85ed1dcb79bfdb9cf1b21 539 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 504 4.0E-41 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_000001020780 5b1e36a1d1c85ed1dcb79bfdb9cf1b21 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 3.9E-7 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_000001020780 5b1e36a1d1c85ed1dcb79bfdb9cf1b21 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 305 334 3.9E-7 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_000001020780 5b1e36a1d1c85ed1dcb79bfdb9cf1b21 539 SMART SM00283 277 538 1.1E-78 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_000001020780 5b1e36a1d1c85ed1dcb79bfdb9cf1b21 539 SMART SM00304 208 262 1.0E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_000001020780 5b1e36a1d1c85ed1dcb79bfdb9cf1b21 539 SUPERFAMILY SSF58104 230 539 1.05E-80 T 13-10-2018 MADE_000001020780 5b1e36a1d1c85ed1dcb79bfdb9cf1b21 539 Gene3D G3DSA:1.10.287.950 207 539 2.2E-72 T 13-10-2018 MADE_1003120 d77fc603248eede3383f13ed4c57907a 80 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 70 1.8E-29 T 13-10-2018 IPR022789 Antitoxin ParD MADE_1003120 d77fc603248eede3383f13ed4c57907a 80 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 1 75 2.6E-35 T 13-10-2018 IPR022789 Antitoxin ParD MADE_1003120 d77fc603248eede3383f13ed4c57907a 80 SUPERFAMILY SSF47598 4 45 2.22E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1003120 d77fc603248eede3383f13ed4c57907a 80 Gene3D G3DSA:1.10.8.1250 10 79 4.8E-24 T 13-10-2018 IPR038296 Antitoxin ParD superfamily MADE_1003905 010729c18a7a57e1e422a602847414fe 362 SUPERFAMILY SSF109604 153 336 2.2E-39 T 13-10-2018 MADE_1003905 010729c18a7a57e1e422a602847414fe 362 Gene3D G3DSA:1.10.3210.10 147 348 1.9E-70 T 13-10-2018 MADE_1003905 010729c18a7a57e1e422a602847414fe 362 Pfam PF00072 Response regulator receiver domain 17 123 1.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1003905 010729c18a7a57e1e422a602847414fe 362 Gene3D G3DSA:3.40.50.2300 3 145 6.3E-38 T 13-10-2018 MADE_1003905 010729c18a7a57e1e422a602847414fe 362 Pfam PF01966 HD domain 175 296 2.2E-19 T 13-10-2018 IPR006674 HD domain MADE_1003905 010729c18a7a57e1e422a602847414fe 362 SMART SM00471 169 306 7.5E-8 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1003905 010729c18a7a57e1e422a602847414fe 362 SUPERFAMILY SSF52172 11 143 7.26E-38 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1003905 010729c18a7a57e1e422a602847414fe 362 SMART SM00448 15 127 3.8E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1003435 5940917a1ad03d9b4684d4c50a54b2b6 225 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 225 130.96 T 13-10-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 MADE_1003435 5940917a1ad03d9b4684d4c50a54b2b6 225 SMART SM00927 56 154 2.4E-50 T 13-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 MADE_1003435 5940917a1ad03d9b4684d4c50a54b2b6 225 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 9 221 7.5E-88 T 13-10-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 MADE_1003435 5940917a1ad03d9b4684d4c50a54b2b6 225 SUPERFAMILY SSF52980 6 223 1.07E-68 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MADE_1003435 5940917a1ad03d9b4684d4c50a54b2b6 225 Pfam PF02976 DNA mismatch repair enzyme MutH 56 154 2.0E-30 T 13-10-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 MADE_1003435 5940917a1ad03d9b4684d4c50a54b2b6 225 Gene3D G3DSA:3.40.600.10 2 223 2.1E-51 T 13-10-2018 IPR037057 DNA mismatch repair MutH/Restriction endonuclease, type II superfamily GO:0003677|GO:0004519 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 Gene3D G3DSA:2.40.50.140 67 129 8.3E-14 T 13-10-2018 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 SUPERFAMILY SSF50249 69 129 1.76E-10 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 Gene3D G3DSA:2.30.30.30 1 64 2.0E-12 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 SMART SM01185 69 124 5.6E-16 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 PIRSF PIRSF005901 1 189 8.5E-62 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 2.9E-17 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 Pfam PF09285 Elongation factor P, C-terminal 132 187 3.6E-22 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 188 41.042 T 13-10-2018 IPR011897 Translation elongation factor P-like, YeiP MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 124 1.2E-13 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 TIGRFAM TIGR02178 yeiP: elongation factor P-like protein YeiP 3 188 6.2E-80 T 13-10-2018 IPR011897 Translation elongation factor P-like, YeiP MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 ProSitePatterns PS01275 Elongation factor P signature. 153 172 - T 13-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 SMART SM00841 132 187 3.6E-31 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 SUPERFAMILY SSF50249 132 188 4.28E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 Gene3D G3DSA:2.40.50.140 131 188 1.4E-23 T 13-10-2018 MADE_000001023460 6f6a8aa61ed50674afaee0e1e49a19da 191 SUPERFAMILY SSF50104 1 65 1.3E-13 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily MADE_1013010 b683a05ce38859dc6965efe86871ce61 388 SUPERFAMILY SSF52440 174 280 1.52E-38 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1013010 b683a05ce38859dc6965efe86871ce61 388 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 387 1.6E-152 T 13-10-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain MADE_1013010 b683a05ce38859dc6965efe86871ce61 388 SUPERFAMILY SSF56059 1 386 2.22E-86 T 13-10-2018 MADE_1013010 b683a05ce38859dc6965efe86871ce61 388 Gene3D G3DSA:3.30.1490.330 264 345 9.3E-21 T 13-10-2018 MADE_1003750 63073b5c955206975bb9f07a3417c2c6 210 SUPERFAMILY SSF52833 27 203 2.07E-40 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1003750 63073b5c955206975bb9f07a3417c2c6 210 PIRSF PIRSF001488 1 210 8.7E-50 T 13-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL MADE_1003750 63073b5c955206975bb9f07a3417c2c6 210 ProSitePatterns PS00194 Thioredoxin family active site. 46 64 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_1003750 63073b5c955206975bb9f07a3417c2c6 210 Pfam PF01323 DSBA-like thioredoxin domain 46 199 3.6E-19 T 13-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 MADE_1003750 63073b5c955206975bb9f07a3417c2c6 210 Gene3D G3DSA:3.40.30.10 23 209 7.7E-48 T 13-10-2018 MADE_1004440 203df5ab45776a1e9acc1700fbc1cc11 142 Gene3D G3DSA:2.20.25.10 1 48 6.9E-22 T 13-10-2018 MADE_1004440 203df5ab45776a1e9acc1700fbc1cc11 142 Gene3D G3DSA:3.30.300.20 49 141 9.7E-33 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1004440 203df5ab45776a1e9acc1700fbc1cc11 142 Pfam PF02566 OsmC-like protein 44 139 1.5E-20 T 13-10-2018 IPR003718 OsmC/Ohr family MADE_1004440 203df5ab45776a1e9acc1700fbc1cc11 142 SUPERFAMILY SSF82784 6 141 1.57E-43 T 13-10-2018 IPR036102 OsmC/Ohr superfamily MADE_1004440 203df5ab45776a1e9acc1700fbc1cc11 142 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 8 140 1.1E-55 T 13-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 361 368 2.1E-8 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.1E-8 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 2.1E-8 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 368 1.1E-6 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 1.1E-6 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-6 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 Gene3D G3DSA:3.50.50.60 6 390 4.6E-129 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 Gene3D G3DSA:1.10.8.260 261 321 4.6E-129 T 13-10-2018 IPR023166 HI0933-like insert domain superfamily MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 391 8.5E-132 T 13-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 Pfam PF03486 HI0933-like protein 5 391 2.5E-153 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 SUPERFAMILY SSF160996 190 337 6.67E-42 T 13-10-2018 MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 SUPERFAMILY SSF51905 4 393 1.45E-60 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1000825 e3ae5d331105722a2f18d54adceda661 393 Gene3D G3DSA:2.40.30.10 188 338 4.6E-129 T 13-10-2018 MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 387 406 2.3E-36 T 13-10-2018 IPR003004 GspF/PilC family MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 69 81 2.3E-36 T 13-10-2018 IPR003004 GspF/PilC family MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 371 385 2.3E-36 T 13-10-2018 IPR003004 GspF/PilC family MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 PRINTS PR00812 Bacterial general secretion pathway protein F signature 168 196 2.3E-36 T 13-10-2018 IPR003004 GspF/PilC family MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 406 4.2E-160 T 13-10-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 Gene3D G3DSA:1.20.81.30 260 369 4.4E-25 T 13-10-2018 MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 Gene3D G3DSA:1.20.81.30 58 175 4.0E-32 T 13-10-2018 MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 168 196 - T 13-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 Pfam PF00482 Type II secretion system (T2SS), protein F 74 196 1.4E-30 T 13-10-2018 IPR018076 Type II secretion system F domain MADE_1019835 4565556dab63a61812b25f0ce3948c41 408 Pfam PF00482 Type II secretion system (T2SS), protein F 276 397 6.1E-25 T 13-10-2018 IPR018076 Type II secretion system F domain MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 SUPERFAMILY SSF103088 92 207 1.7E-38 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 ProSitePatterns PS01068 OmpA-like domain. 137 181 - T 13-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 Pfam PF00691 OmpA family 104 199 1.5E-22 T 13-10-2018 IPR006665 OmpA-like domain MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 Pfam PF13488 Glycine zipper 29 74 7.0E-14 T 13-10-2018 IPR039567 Glycine zipper domain MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 Gene3D G3DSA:3.30.1330.60 68 213 4.7E-47 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 PRINTS PR01021 OMPA domain signature 105 127 1.7E-13 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 PRINTS PR01021 OMPA domain signature 150 166 1.7E-13 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1020415 511dec31d10a832b0fb2587860fc47cd 213 PRINTS PR01021 OMPA domain signature 135 150 1.7E-13 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1002495 25b1f211f74aac360adae8da0e0ed4a6 268 SMART SM01150 5 266 1.3E-111 T 13-10-2018 IPR009770 Domain of unknown function DUF1338 MADE_1002495 25b1f211f74aac360adae8da0e0ed4a6 268 Pfam PF07063 Domain of unknown function (DUF1338) 138 265 1.1E-25 T 13-10-2018 IPR009770 Domain of unknown function DUF1338 MADE_1002495 25b1f211f74aac360adae8da0e0ed4a6 268 Pfam PF07063 Domain of unknown function (DUF1338) 7 124 1.9E-24 T 13-10-2018 IPR009770 Domain of unknown function DUF1338 MADE_1002495 25b1f211f74aac360adae8da0e0ed4a6 268 Gene3D G3DSA:3.10.180.50 2 243 1.8E-93 T 13-10-2018 MADE_000001023580 b147ea9e63dc1d2500e921bfd66f992b 380 Pfam PF13484 4Fe-4S double cluster binding domain 195 258 1.2E-19 T 13-10-2018 MADE_000001023580 b147ea9e63dc1d2500e921bfd66f992b 380 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 195 206 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site MADE_000001023580 b147ea9e63dc1d2500e921bfd66f992b 380 Pfam PF08331 Domain of unknown function (DUF1730) 64 142 2.3E-24 T 13-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 MADE_000001023580 b147ea9e63dc1d2500e921bfd66f992b 380 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 9 317 50.431 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MADE_000001023580 b147ea9e63dc1d2500e921bfd66f992b 380 SUPERFAMILY SSF46548 141 258 1.15E-18 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 MADE_000001023580 b147ea9e63dc1d2500e921bfd66f992b 380 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 16 351 2.8E-155 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 MADE_1005990 1c16a78db10d0e9bb120ddba764e3a50 127 Pfam PF00072 Response regulator receiver domain 7 119 7.0E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1005990 1c16a78db10d0e9bb120ddba764e3a50 127 SUPERFAMILY SSF52172 4 125 3.56E-38 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1005990 1c16a78db10d0e9bb120ddba764e3a50 127 Gene3D G3DSA:3.40.50.2300 1 126 7.6E-41 T 13-10-2018 MADE_1005990 1c16a78db10d0e9bb120ddba764e3a50 127 SMART SM00448 5 119 2.2E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011945 0d73d53dd60086eec2c46d4f8dad8986 573 Gene3D G3DSA:3.40.710.10 49 370 4.6E-96 T 13-10-2018 MADE_1011945 0d73d53dd60086eec2c46d4f8dad8986 573 SUPERFAMILY SSF56601 42 367 6.2E-89 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1011945 0d73d53dd60086eec2c46d4f8dad8986 573 Pfam PF00144 Beta-lactamase 41 351 2.1E-63 T 13-10-2018 IPR001466 Beta-lactamase-related MADE_1013350 e0c9d1088c50bb969d7295fbd64162ba 142 Pfam PF01475 Ferric uptake regulator family 9 129 7.3E-47 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MADE_1013350 e0c9d1088c50bb969d7295fbd64162ba 142 Gene3D G3DSA:3.30.1490.190 84 140 4.3E-23 T 13-10-2018 MADE_1013350 e0c9d1088c50bb969d7295fbd64162ba 142 Gene3D G3DSA:1.10.10.10 1 83 2.8E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1013350 e0c9d1088c50bb969d7295fbd64162ba 142 SUPERFAMILY SSF46785 3 133 4.74E-44 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1006875 f1f14aa6a8e5674370281c4fb31b3602 269 SUPERFAMILY SSF51366 1 266 6.69E-87 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MADE_1006875 f1f14aa6a8e5674370281c4fb31b3602 269 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 36.354 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1006875 f1f14aa6a8e5674370281c4fb31b3602 269 Gene3D G3DSA:3.20.20.70 1 268 8.5E-93 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1006875 f1f14aa6a8e5674370281c4fb31b3602 269 Pfam PF00290 Tryptophan synthase alpha chain 9 266 1.7E-89 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1006875 f1f14aa6a8e5674370281c4fb31b3602 269 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 9 263 1.3E-96 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1006875 f1f14aa6a8e5674370281c4fb31b3602 269 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 13-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1019650 3cc964fa15ccebad4d92dcf407f2b3f0 299 Gene3D G3DSA:2.70.70.10 158 295 1.1E-37 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1019650 3cc964fa15ccebad4d92dcf407f2b3f0 299 Pfam PF01551 Peptidase family M23 183 280 8.6E-22 T 13-10-2018 IPR016047 Peptidase M23 MADE_1019650 3cc964fa15ccebad4d92dcf407f2b3f0 299 SUPERFAMILY SSF51261 87 282 2.72E-30 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1007235 23ab615b96d7e87de63d6f4d3591d966 429 Pfam PF11814 Peptidase_C39 like family 224 425 5.6E-83 T 13-10-2018 IPR021770 Protein of unknown function DUF3335 MADE_1007235 23ab615b96d7e87de63d6f4d3591d966 429 Pfam PF00583 Acetyltransferase (GNAT) family 89 190 6.6E-12 T 13-10-2018 IPR000182 GNAT domain MADE_1007235 23ab615b96d7e87de63d6f4d3591d966 429 Gene3D G3DSA:3.40.630.30 47 231 2.1E-29 T 13-10-2018 MADE_1007235 23ab615b96d7e87de63d6f4d3591d966 429 SUPERFAMILY SSF55729 47 213 1.35E-24 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1009070 1808bdb826877869d52d378cc4c491a8 441 PIRSF PIRSF029172 36 440 6.8E-124 T 13-10-2018 IPR027020 Protein ynjB MADE_1009070 1808bdb826877869d52d378cc4c491a8 441 Gene3D G3DSA:3.40.190.10 191 340 1.1E-12 T 13-10-2018 MADE_1009070 1808bdb826877869d52d378cc4c491a8 441 SUPERFAMILY SSF53850 73 437 1.63E-30 T 13-10-2018 MADE_1009070 1808bdb826877869d52d378cc4c491a8 441 Pfam PF13416 Bacterial extracellular solute-binding protein 96 377 1.6E-20 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein MADE_1009070 1808bdb826877869d52d378cc4c491a8 441 Gene3D G3DSA:3.40.190.10 116 377 1.1E-12 T 13-10-2018 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 Gene3D G3DSA:1.10.1740.10 308 392 1.4E-25 T 13-10-2018 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 PIRSF PIRSF006205 1 394 2.8E-146 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 SUPERFAMILY SSF55347 126 270 1.34E-60 T 13-10-2018 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 Pfam PF13288 DXP reductoisomerase C-terminal domain 267 382 5.0E-36 T 13-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 235 1.2E-36 T 13-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 388 45.231 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 385 1.1E-153 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 SUPERFAMILY SSF51735 2 150 5.06E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 2.0E-44 T 13-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 SUPERFAMILY SSF69055 298 390 2.75E-28 T 13-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 MADE_1005350 0d9b97abed9c72a41e116c965b25f720 395 Gene3D G3DSA:3.40.50.720 1 150 1.6E-51 T 13-10-2018 MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 24 173 3.2E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 SUPERFAMILY SSF88946 20 111 9.02E-20 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 Pfam PF08281 Sigma-70, region 4 117 169 1.6E-12 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 Gene3D G3DSA:1.10.10.10 112 176 2.4E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 Pfam PF04542 Sigma-70 region 2 26 92 1.5E-14 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 Gene3D G3DSA:1.10.1740.10 3 88 2.6E-18 T 13-10-2018 MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 SUPERFAMILY SSF88659 115 174 1.5E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1006760 5b6b0aa7e0bfcfa816ece609ede10e5d 185 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 48 79 - T 13-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1007780 44d84b2885188a11bde7cb38ee79aab1 99 Pfam PF11446 Protein of unknown function (DUF2897) 3 44 3.2E-15 T 13-10-2018 IPR021550 Protein of unknown function DUF2897 MADE_1013290 76788e0bed76c20b913b9146d83826a6 178 Pfam PF00156 Phosphoribosyl transferase domain 28 144 3.6E-10 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MADE_1013290 76788e0bed76c20b913b9146d83826a6 178 SUPERFAMILY SSF53271 6 175 1.2E-48 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like MADE_1013290 76788e0bed76c20b913b9146d83826a6 178 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 6 175 36.988 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MADE_1013290 76788e0bed76c20b913b9146d83826a6 178 Gene3D G3DSA:3.40.50.2020 2 178 1.3E-62 T 13-10-2018 MADE_1013290 76788e0bed76c20b913b9146d83826a6 178 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 6 174 3.7E-68 T 13-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 MADE_1013880 ac7b1266ff1e5366e65fd84e1fc63e7f 225 Pfam PF03567 Sulfotransferase family 3 220 5.8E-20 T 13-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 MADE_1013880 ac7b1266ff1e5366e65fd84e1fc63e7f 225 Gene3D G3DSA:3.40.50.300 80 225 6.8E-6 T 13-10-2018 MADE_1013880 ac7b1266ff1e5366e65fd84e1fc63e7f 225 SUPERFAMILY SSF52540 10 224 3.72E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012555 8a78cefd766a7e70c44faf00b08cc8fb 291 PRINTS PR01483 Fatty acid synthase signature 180 202 4.5E-6 T 13-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MADE_1012555 8a78cefd766a7e70c44faf00b08cc8fb 291 PRINTS PR01483 Fatty acid synthase signature 202 223 4.5E-6 T 13-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 MADE_1012555 8a78cefd766a7e70c44faf00b08cc8fb 291 Gene3D G3DSA:3.10.129.10 26 286 2.1E-53 T 13-10-2018 MADE_1012555 8a78cefd766a7e70c44faf00b08cc8fb 291 SUPERFAMILY SSF54637 180 285 5.67E-23 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1012555 8a78cefd766a7e70c44faf00b08cc8fb 291 Pfam PF01575 MaoC like domain 184 273 1.1E-20 T 13-10-2018 IPR002539 MaoC-like dehydratase domain MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 PIRSF PIRSF000109 9 513 1.2E-185 T 13-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 Gene3D G3DSA:1.20.5.320 472 506 9.1E-18 T 13-10-2018 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 SUPERFAMILY SSF51735 14 181 2.18E-38 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 15 507 2.6E-182 T 13-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 284 311 6.5E-38 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 83 112 6.5E-38 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 14 37 6.5E-38 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 393 415 6.5E-38 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 Gene3D G3DSA:1.10.1040.10 215 471 1.1E-105 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 SMART SM01350 213 506 5.9E-212 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 Gene3D G3DSA:3.40.50.720 3 214 2.0E-45 T 13-10-2018 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 15 181 8.9E-36 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 SUPERFAMILY SSF48179 211 507 7.48E-123 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 288 300 - T 13-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_1011655 1d9c3013d71fd44d3d96fdd76ca1a852 517 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 213 505 7.1E-128 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 MADE_000001022940 483b4bfc79e7273de98d456658404365 82 Pfam PF07866 Protein of unknown function (DUF1653) 11 71 6.3E-27 T 13-10-2018 IPR023387 DUF1653-like domain MADE_000001022940 483b4bfc79e7273de98d456658404365 82 Gene3D G3DSA:2.30.30.320 2 81 4.0E-28 T 13-10-2018 IPR037135 DUF1653-like domain superfamily MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82693 138 332 1.34E-28 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82714 187 274 8.89E-19 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:1.20.1640.10 10 522 0.0 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 2.7E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:3.30.2090.10 731 819 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:3.30.70.1440 679 876 0.0 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:3.30.70.1430 40 827 0.0 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82693 575 681 2.67E-26 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82866 841 1038 4.32E-45 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:1.20.1640.10 523 1033 0.0 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:3.30.2090.10 181 277 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Pfam PF00873 AcrB/AcrD/AcrF family 3 1036 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82693 41 134 3.4E-27 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:3.30.70.1430 577 678 0.0 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82866 298 498 1.24E-51 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1038 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 Gene3D G3DSA:3.30.70.1320 135 334 0.0 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82693 682 867 3.4E-25 T 13-10-2018 MADE_1014945 c9433aab4fce03ab8d86a41bacf6db30 1040 SUPERFAMILY SSF82714 732 817 3.66E-20 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 Gene3D G3DSA:3.40.50.300 347 562 3.7E-50 T 13-10-2018 MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 SUPERFAMILY SSF52540 359 553 5.06E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 Pfam PF00005 ABC transporter 379 517 6.7E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 Gene3D G3DSA:1.20.1560.10 5 341 3.8E-34 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 SUPERFAMILY SSF90123 24 335 1.44E-39 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 SMART SM00382 386 563 1.2E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 Pfam PF00664 ABC transporter transmembrane region 35 295 6.0E-20 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_1000450 9698cd2c8b4702da9a879dcd0f72163e 563 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 28 554 9.7E-138 T 13-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 Pfam PF00154 recA bacterial DNA recombination protein 7 268 2.8E-145 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 Gene3D G3DSA:3.30.250.10 268 343 3.9E-27 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 SUPERFAMILY SSF52540 3 267 1.59E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 Gene3D G3DSA:3.40.50.300 26 267 1.2E-82 T 13-10-2018 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 ProSitePatterns PS00321 recA signature. 213 221 - T 13-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 SMART SM00382 57 228 1.2E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 3.7E-174 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 PRINTS PR00142 RecA protein signature 165 194 6.9E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 PRINTS PR00142 RecA protein signature 297 314 6.9E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 PRINTS PR00142 RecA protein signature 127 156 6.9E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 PRINTS PR00142 RecA protein signature 210 238 6.9E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 PRINTS PR00142 RecA protein signature 243 272 6.9E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 PRINTS PR00142 RecA protein signature 93 122 6.9E-84 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 SUPERFAMILY SSF54752 268 324 3.79E-21 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal MADE_1004735 5b8baf6e93f7f242d562846dfa36d44e 348 Hamap MF_00268 Protein RecA [recA]. 5 329 51.519 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 MADE_000001020870 4d70e06258d4ddcfb49ef995252e4df1 207 Pfam PF02796 Helix-turn-helix domain of resolvase 161 199 3.5E-6 T 13-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 MADE_000001020870 4d70e06258d4ddcfb49ef995252e4df1 207 Pfam PF00239 Resolvase, N terminal domain 5 157 1.0E-24 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MADE_000001020870 4d70e06258d4ddcfb49ef995252e4df1 207 SUPERFAMILY SSF53041 1 159 3.14E-28 T 13-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 MADE_000001020870 4d70e06258d4ddcfb49ef995252e4df1 207 Gene3D G3DSA:3.40.50.1390 3 141 1.5E-27 T 13-10-2018 MADE_000001020870 4d70e06258d4ddcfb49ef995252e4df1 207 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 13-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 MADE_000001020870 4d70e06258d4ddcfb49ef995252e4df1 207 SMART SM00857 3 159 3.0E-29 T 13-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 MADE_1000420 c3c3098b087bce216595a4e320d86804 284 SMART SM00849 12 202 9.2E-24 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1000420 c3c3098b087bce216595a4e320d86804 284 Pfam PF00753 Metallo-beta-lactamase superfamily 54 202 6.0E-20 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1000420 c3c3098b087bce216595a4e320d86804 284 SUPERFAMILY SSF56281 6 213 6.91E-43 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1000420 c3c3098b087bce216595a4e320d86804 284 Gene3D G3DSA:3.60.15.10 1 284 3.4E-97 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 Pfam PF13437 HlyD family secretion protein 180 282 3.5E-11 T 13-10-2018 MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 SUPERFAMILY SSF111369 57 277 7.45E-22 T 13-10-2018 MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 Gene3D G3DSA:2.40.420.20 304 367 1.1E-42 T 13-10-2018 MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 Pfam PF13533 Biotin-lipoyl like 66 117 8.2E-7 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 42 369 6.4E-39 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 Gene3D G3DSA:2.40.30.170 54 303 1.1E-42 T 13-10-2018 MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 Gene3D G3DSA:1.10.287.470 103 177 1.1E-42 T 13-10-2018 MADE_000001021345 68aa295517276c44c5b81a0cf6c4cebf 382 Gene3D G3DSA:2.40.50.100 66 211 1.1E-42 T 13-10-2018 MADE_1008730 fb815a508ccc9919920d49feb55404ab 295 Pfam PF13177 DNA polymerase III, delta subunit 10 158 6.3E-45 T 13-10-2018 MADE_1008730 fb815a508ccc9919920d49feb55404ab 295 SUPERFAMILY SSF52540 4 188 1.42E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008730 fb815a508ccc9919920d49feb55404ab 295 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 16 189 3.1E-54 T 13-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1008730 fb815a508ccc9919920d49feb55404ab 295 Gene3D G3DSA:3.40.50.300 2 162 9.2E-49 T 13-10-2018 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 SUPERFAMILY SSF47240 1 153 2.5E-47 T 13-10-2018 IPR009078 Ferritin-like superfamily MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PIRSF PIRSF002560 1 157 1.5E-64 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 Pfam PF00210 Ferritin-like domain 9 137 1.2E-33 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PRINTS PR00601 Bacterioferritin signature 86 106 1.3E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PRINTS PR00601 Bacterioferritin signature 65 85 1.3E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PRINTS PR00601 Bacterioferritin signature 3 22 1.3E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PRINTS PR00601 Bacterioferritin signature 23 43 1.3E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PRINTS PR00601 Bacterioferritin signature 44 64 1.3E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PRINTS PR00601 Bacterioferritin signature 107 127 1.3E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 PRINTS PR00601 Bacterioferritin signature 128 149 1.3E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 3.1E-68 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001022050 832c44caaa1b57116559d5c3d28deaa7 158 Gene3D G3DSA:1.20.1260.10 1 157 5.7E-63 T 13-10-2018 IPR012347 Ferritin-like MADE_1013915 b6f62115b73775720fa66ed08be795d7 468 Gene3D G3DSA:3.90.550.10 1 341 2.6E-123 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013915 b6f62115b73775720fa66ed08be795d7 468 Gene3D G3DSA:2.60.120.10 342 453 6.5E-21 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1013915 b6f62115b73775720fa66ed08be795d7 468 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1 465 5.5E-229 T 13-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MADE_1013915 b6f62115b73775720fa66ed08be795d7 468 Pfam PF00483 Nucleotidyl transferase 2 283 1.9E-73 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MADE_1013915 b6f62115b73775720fa66ed08be795d7 468 SUPERFAMILY SSF53448 1 276 8.56E-74 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013915 b6f62115b73775720fa66ed08be795d7 468 Pfam PF01050 Mannose-6-phosphate isomerase 311 461 1.4E-73 T 13-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MADE_1013915 b6f62115b73775720fa66ed08be795d7 468 SUPERFAMILY SSF51182 181 465 7.33E-91 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1001370 b034e68f2c85e383f9222f54fa9fb88d 360 Gene3D G3DSA:3.40.50.150 1 177 3.8E-34 T 13-10-2018 MADE_1001370 b034e68f2c85e383f9222f54fa9fb88d 360 Gene3D G3DSA:3.40.50.150 179 360 8.1E-39 T 13-10-2018 MADE_1001370 b034e68f2c85e383f9222f54fa9fb88d 360 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 289 295 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1001370 b034e68f2c85e383f9222f54fa9fb88d 360 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 3 360 39.239 T 13-10-2018 IPR023543 rRNA small subunit methyltransferase C GO:0008649 MADE_1001370 b034e68f2c85e383f9222f54fa9fb88d 360 SUPERFAMILY SSF53335 178 339 1.91E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1001370 b034e68f2c85e383f9222f54fa9fb88d 360 Pfam PF08468 Methyltransferase small domain N-terminal 7 181 7.2E-29 T 13-10-2018 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 MADE_1001370 b034e68f2c85e383f9222f54fa9fb88d 360 Pfam PF05175 Methyltransferase small domain 191 357 1.9E-51 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MADE_1015305 907fd3a457e124348b74ad94fe8609a6 265 Pfam PF01435 Peptidase family M48 68 246 1.5E-39 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MADE_1015305 907fd3a457e124348b74ad94fe8609a6 265 Gene3D G3DSA:3.30.2010.10 54 144 2.3E-6 T 13-10-2018 MADE_1003615 49af65a60a8f71b27629a96476a30c72 322 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 15 317 7.6E-123 T 13-10-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 MADE_1003615 49af65a60a8f71b27629a96476a30c72 322 PRINTS PR00982 Lysyl-tRNA synthetase signature 96 113 2.5E-5 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1003615 49af65a60a8f71b27629a96476a30c72 322 PRINTS PR00982 Lysyl-tRNA synthetase signature 28 38 2.5E-5 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 MADE_1003615 49af65a60a8f71b27629a96476a30c72 322 Pfam PF00152 tRNA synthetases class II (D, K and N) 14 318 2.3E-38 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1003615 49af65a60a8f71b27629a96476a30c72 322 Gene3D G3DSA:3.30.930.10 1 322 3.5E-104 T 13-10-2018 MADE_1003615 49af65a60a8f71b27629a96476a30c72 322 SUPERFAMILY SSF55681 11 317 2.9E-77 T 13-10-2018 MADE_1014195 921cb54afec8c90baaeed8ccace06059 224 SUPERFAMILY SSF55469 19 223 1.7E-41 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_1014195 921cb54afec8c90baaeed8ccace06059 224 Gene3D G3DSA:3.40.109.10 9 223 1.6E-51 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_1014195 921cb54afec8c90baaeed8ccace06059 224 Pfam PF00881 Nitroreductase family 32 200 6.7E-20 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MADE_1010765 361c61dd85509ddf752b884eb7ec3569 234 Pfam PF13489 Methyltransferase domain 50 198 1.0E-22 T 13-10-2018 MADE_1010765 361c61dd85509ddf752b884eb7ec3569 234 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 8 233 37.022 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MADE_1010765 361c61dd85509ddf752b884eb7ec3569 234 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 8 227 7.9E-85 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MADE_1010765 361c61dd85509ddf752b884eb7ec3569 234 SUPERFAMILY SSF53335 11 211 1.59E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1010765 361c61dd85509ddf752b884eb7ec3569 234 Gene3D G3DSA:3.40.50.150 8 232 2.6E-74 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Hamap MF_01973 Lon protease [lon]. 11 772 72.293 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Gene3D G3DSA:3.30.230.10 585 772 1.3E-85 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 1.1E-55 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 1.1E-55 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 1.1E-55 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 1.1E-55 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 1.1E-55 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 SUPERFAMILY SSF52540 314 588 2.07E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Gene3D G3DSA:3.40.50.300 314 490 1.5E-61 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 SMART SM00382 348 492 7.8E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Gene3D G3DSA:1.10.8.60 491 584 1.3E-32 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 PIRSF PIRSF001174 1 774 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 SMART SM00464 10 202 1.5E-80 T 13-10-2018 IPR003111 Lon, substrate-binding domain MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 SUPERFAMILY SSF54211 595 770 2.39E-59 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 13-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Gene3D G3DSA:1.20.58.1480 121 245 2.0E-45 T 13-10-2018 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 SUPERFAMILY SSF88697 10 201 3.23E-50 T 13-10-2018 IPR015947 PUA-like superfamily MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 1.1E-99 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 5.0E-17 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 201 8.8E-42 T 13-10-2018 IPR003111 Lon, substrate-binding domain MADE_1012745 4b3794ca19f9e031723d7088f36c054a 783 Gene3D G3DSA:2.30.130.40 1 118 1.2E-36 T 13-10-2018 MADE_1002630 0c6ca123de77a9ce222e1b0b4973349f 288 PIRSF PIRSF037442 2 286 3.5E-75 T 13-10-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 MADE_1002630 0c6ca123de77a9ce222e1b0b4973349f 288 Pfam PF12146 Serine aminopeptidase, S33 29 119 1.6E-11 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 MADE_1002630 0c6ca123de77a9ce222e1b0b4973349f 288 SUPERFAMILY SSF53474 8 284 1.13E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1002630 0c6ca123de77a9ce222e1b0b4973349f 288 Gene3D G3DSA:3.40.50.1820 5 288 3.1E-21 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1009765 10acf2b6a1acd34e8bce11e674b36ddb 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 4.4E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009765 10acf2b6a1acd34e8bce11e674b36ddb 300 SUPERFAMILY SSF46785 6 116 5.2E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1009765 10acf2b6a1acd34e8bce11e674b36ddb 300 Gene3D G3DSA:1.10.10.10 7 91 1.8E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009765 10acf2b6a1acd34e8bce11e674b36ddb 300 Pfam PF03466 LysR substrate binding domain 93 297 2.8E-35 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1009765 10acf2b6a1acd34e8bce11e674b36ddb 300 SUPERFAMILY SSF53850 94 297 4.89E-39 T 13-10-2018 MADE_1009765 10acf2b6a1acd34e8bce11e674b36ddb 300 Gene3D G3DSA:3.40.190.290 96 297 2.0E-53 T 13-10-2018 MADE_000001021555 fa9785ffea2dd2df4d6b345615089b95 252 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_000001021555 fa9785ffea2dd2df4d6b345615089b95 252 SUPERFAMILY SSF52540 23 246 1.0E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001021555 fa9785ffea2dd2df4d6b345615089b95 252 Pfam PF00005 ABC transporter 40 188 1.9E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_000001021555 fa9785ffea2dd2df4d6b345615089b95 252 SMART SM00382 49 237 1.5E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001021555 fa9785ffea2dd2df4d6b345615089b95 252 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 23 239 9.0E-102 T 13-10-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0016020|GO:0044873 MADE_000001021555 fa9785ffea2dd2df4d6b345615089b95 252 Gene3D G3DSA:3.40.50.300 22 251 2.1E-71 T 13-10-2018 MADE_1018920 8a65be1af71f1e3e87beb15bc964e090 191 SUPERFAMILY SSF88946 17 112 4.91E-29 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1018920 8a65be1af71f1e3e87beb15bc964e090 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 183 2.2E-24 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1018920 8a65be1af71f1e3e87beb15bc964e090 191 Pfam PF08281 Sigma-70, region 4 138 182 4.4E-10 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1018920 8a65be1af71f1e3e87beb15bc964e090 191 Pfam PF04542 Sigma-70 region 2 38 104 1.0E-16 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1018920 8a65be1af71f1e3e87beb15bc964e090 191 SUPERFAMILY SSF88659 131 186 5.89E-10 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1018920 8a65be1af71f1e3e87beb15bc964e090 191 Gene3D G3DSA:1.10.1740.10 15 128 2.0E-30 T 13-10-2018 MADE_1018920 8a65be1af71f1e3e87beb15bc964e090 191 Gene3D G3DSA:1.10.10.10 129 187 3.5E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015755 45cddd31237c49736308b4028d99386a 401 SUPERFAMILY SSF48208 7 398 2.09E-116 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MADE_1015755 45cddd31237c49736308b4028d99386a 401 Gene3D G3DSA:1.50.10.10 4 400 1.5E-138 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MADE_1015755 45cddd31237c49736308b4028d99386a 401 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 34 389 5.3E-101 T 13-10-2018 MADE_1004495 2667c0d7aab82b6fd31fb6ecbd628995 419 TIGRFAM TIGR01224 hutI: imidazolonepropionase 79 417 1.7E-127 T 13-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004495 2667c0d7aab82b6fd31fb6ecbd628995 419 Pfam PF01979 Amidohydrolase family 79 419 3.4E-15 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_1004495 2667c0d7aab82b6fd31fb6ecbd628995 419 SUPERFAMILY SSF51556 81 378 1.68E-79 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1004495 2667c0d7aab82b6fd31fb6ecbd628995 419 Gene3D G3DSA:2.30.40.10 11 416 3.5E-150 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1004495 2667c0d7aab82b6fd31fb6ecbd628995 419 Hamap MF_00372 Imidazolonepropionase [hutI]. 6 419 38.063 T 13-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004495 2667c0d7aab82b6fd31fb6ecbd628995 419 Gene3D G3DSA:3.20.20.140 82 379 3.5E-150 T 13-10-2018 MADE_1004495 2667c0d7aab82b6fd31fb6ecbd628995 419 SUPERFAMILY SSF51338 5 418 1.07E-20 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1004490 756c682817440fb16d44e006a8857ddc 334 PIRSF PIRSF036979 25 333 1.3E-26 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 MADE_1004490 756c682817440fb16d44e006a8857ddc 334 SUPERFAMILY SSF52768 4 329 1.8E-68 T 13-10-2018 IPR023696 Ureohydrolase domain superfamily MADE_1004490 756c682817440fb16d44e006a8857ddc 334 TIGRFAM TIGR01227 hutG: formimidoylglutamase 4 327 1.5E-85 T 13-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MADE_1004490 756c682817440fb16d44e006a8857ddc 334 Gene3D G3DSA:3.40.800.10 1 333 6.3E-96 T 13-10-2018 MADE_1004490 756c682817440fb16d44e006a8857ddc 334 Pfam PF00491 Arginase family 50 326 1.0E-49 T 13-10-2018 IPR006035 Ureohydrolase GO:0046872 MADE_1004490 756c682817440fb16d44e006a8857ddc 334 Hamap MF_00737 Formimidoylglutamase [hutG]. 3 328 35.957 T 13-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 MADE_1011900 3c3b7a823fec17d659ed5c63060611f4 270 SUPERFAMILY SSF53850 34 262 3.75E-21 T 13-10-2018 MADE_1011900 3c3b7a823fec17d659ed5c63060611f4 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 250 1.6E-8 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1011900 3c3b7a823fec17d659ed5c63060611f4 270 Gene3D G3DSA:3.40.190.10 33 245 6.9E-14 T 13-10-2018 MADE_1011900 3c3b7a823fec17d659ed5c63060611f4 270 Gene3D G3DSA:3.40.190.10 119 217 6.9E-14 T 13-10-2018 MADE_1015605 0d1fca2f386e730bff019dc5664aa089 376 PIRSF PIRSF038941 2 376 4.1E-161 T 13-10-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 MADE_1015605 0d1fca2f386e730bff019dc5664aa089 376 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 173 332 8.6E-9 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 MADE_1015605 0d1fca2f386e730bff019dc5664aa089 376 TIGRFAM TIGR01047 nspC: carboxynorspermidine decarboxylase 10 374 3.2E-159 T 13-10-2018 IPR005730 Carboxynorspermidine decarboxylase GO:0016831|GO:0045312 KEGG: 00330+4.1.1.96|MetaCyc: PWY-6562 MADE_1015605 0d1fca2f386e730bff019dc5664aa089 376 Gene3D G3DSA:3.20.20.10 19 244 1.8E-153 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1015605 0d1fca2f386e730bff019dc5664aa089 376 Gene3D G3DSA:2.40.37.10 10 371 1.8E-153 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1015605 0d1fca2f386e730bff019dc5664aa089 376 SUPERFAMILY SSF50621 212 365 6.7E-31 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1015605 0d1fca2f386e730bff019dc5664aa089 376 SUPERFAMILY SSF51419 19 247 6.32E-43 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1012120 a6ecf8b4342d0827bc604f7aa352b654 241 Pfam PF07273 Protein of unknown function (DUF1439) 31 131 3.7E-7 T 13-10-2018 IPR010835 Protein of unknown function DUF1439 MADE_1015300 2d6da5c272fca9513865feb4be4a9594 600 Gene3D G3DSA:2.130.10.10 67 320 5.5E-7 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1015300 2d6da5c272fca9513865feb4be4a9594 600 SUPERFAMILY SSF75011 74 535 7.19E-9 T 13-10-2018 MADE_1015300 2d6da5c272fca9513865feb4be4a9594 600 Gene3D G3DSA:1.20.5.320 24 66 7.9E-7 T 13-10-2018 MADE_000001021960 29d120572498c0d730826332c0025893 350 Gene3D G3DSA:3.90.15.10 121 241 2.3E-68 T 13-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 MADE_000001021960 29d120572498c0d730826332c0025893 350 Gene3D G3DSA:3.30.66.10 10 97 3.0E-25 T 13-10-2018 IPR035447 DNA topoisomerase I, N-terminal MADE_000001021960 29d120572498c0d730826332c0025893 350 SUPERFAMILY SSF56349 86 326 8.24E-51 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_000001021960 29d120572498c0d730826332c0025893 350 SUPERFAMILY SSF55869 30 90 9.42E-17 T 13-10-2018 IPR035447 DNA topoisomerase I, N-terminal MADE_000001021960 29d120572498c0d730826332c0025893 350 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 89 317 1.9E-22 T 13-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 MADE_000001021960 29d120572498c0d730826332c0025893 350 Gene3D G3DSA:1.10.132.120 98 321 2.3E-68 T 13-10-2018 MADE_1004935 a3e88738c088fc70ca2bc5eea0159b52 112 Gene3D G3DSA:1.20.1440.40 5 108 2.4E-22 T 13-10-2018 IPR036814 YqcC-like superfamily MADE_1004935 a3e88738c088fc70ca2bc5eea0159b52 112 Pfam PF04287 tRNA pseudouridine synthase C 11 105 1.7E-21 T 13-10-2018 IPR023376 YqcC-like domain MADE_1004935 a3e88738c088fc70ca2bc5eea0159b52 112 SUPERFAMILY SSF158452 10 108 2.62E-23 T 13-10-2018 IPR036814 YqcC-like superfamily MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 SUPERFAMILY SSF55008 16 89 1.83E-16 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 Pfam PF00403 Heavy-metal-associated domain 24 84 1.6E-9 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 PRINTS PR00946 Mercury scavenger protein signature 30 46 2.5E-26 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 PRINTS PR00946 Mercury scavenger protein signature 61 75 2.5E-26 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 PRINTS PR00946 Mercury scavenger protein signature 19 30 2.5E-26 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 PRINTS PR00946 Mercury scavenger protein signature 46 61 2.5E-26 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 PRINTS PR00946 Mercury scavenger protein signature 75 89 2.5E-26 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 TIGRFAM TIGR02052 MerP: mercuric transport protein periplasmic component 1 89 2.2E-34 T 13-10-2018 IPR011795 Mercuric transport protein periplasmic component GO:0015097|GO:0015694|GO:0042597|GO:0045340|GO:0046689 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 Gene3D G3DSA:3.30.70.100 15 92 2.3E-16 T 13-10-2018 MADE_1010350 3be9cd80b2c5726ba339068c3faa5bdb 92 ProSitePatterns PS01047 Heavy-metal-associated domain. 27 56 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MADE_1007480 c0f2f3b042bd8f4da915ce219a4c4b11 470 Gene3D G3DSA:3.40.50.720 141 258 2.3E-7 T 13-10-2018 MADE_1007480 c0f2f3b042bd8f4da915ce219a4c4b11 470 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 20 469 1.7E-108 T 13-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase MADE_1007480 c0f2f3b042bd8f4da915ce219a4c4b11 470 Pfam PF02397 Bacterial sugar transferase 281 465 5.4E-63 T 13-10-2018 IPR003362 Bacterial sugar transferase MADE_1007480 c0f2f3b042bd8f4da915ce219a4c4b11 470 TIGRFAM TIGR03013 EpsB_2: sugar transferase, PEP-CTERM system associated 28 469 3.6E-162 T 13-10-2018 IPR017464 Sugar transferase, PEP-CTERM system associated MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 Gene3D G3DSA:1.10.579.10 153 276 4.8E-52 T 13-10-2018 MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 TIGRFAM TIGR02765 crypto_DASH: cryptochrome, DASH family 1 276 1.7E-115 T 13-10-2018 IPR014133 Cryptochrome DASH GO:0003913|GO:0006281 MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 Pfam PF03441 FAD binding domain of DNA photolyase 132 276 4.2E-42 T 13-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 PRINTS PR00147 DNA photolyase signature 199 217 1.3E-11 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 PRINTS PR00147 DNA photolyase signature 179 195 1.3E-11 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 PRINTS PR00147 DNA photolyase signature 238 252 1.3E-11 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 Gene3D G3DSA:1.25.40.80 1 152 5.3E-42 T 13-10-2018 MADE_1010200 66e8760c72003cc6f5dbe08467108485 276 SUPERFAMILY SSF48173 52 276 5.23E-70 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 150 251 4.6E-9 T 13-10-2018 IPR000014 PAS domain MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1 122 3.2E-24 T 13-10-2018 IPR000014 PAS domain MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 Gene3D G3DSA:3.30.70.270 256 426 2.7E-46 T 13-10-2018 MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 Gene3D G3DSA:3.30.450.20 139 249 1.4E-17 T 13-10-2018 MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SMART SM00086 73 115 3.1E-10 T 13-10-2018 IPR001610 PAC motif MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SMART SM00086 202 244 0.0025 T 13-10-2018 IPR001610 PAC motif MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 258 420 7.5E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SUPERFAMILY SSF55785 10 117 4.99E-22 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SUPERFAMILY SSF55073 267 420 6.28E-39 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 Gene3D G3DSA:3.30.450.20 2 138 4.2E-24 T 13-10-2018 MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SMART SM00267 251 422 1.2E-37 T 13-10-2018 IPR000160 GGDEF domain MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 Pfam PF00990 Diguanylate cyclase, GGDEF domain 263 415 3.7E-39 T 13-10-2018 IPR000160 GGDEF domain MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 Pfam PF08447 PAS fold 23 109 1.5E-12 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 Pfam PF08447 PAS fold 154 237 8.6E-12 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SUPERFAMILY SSF55785 141 245 1.9E-13 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SMART SM00091 1 66 0.0037 T 13-10-2018 IPR000014 PAS domain MADE_1007905 6d1170ee9f2e7de5985a2374ca616f3f 427 SMART SM00091 127 198 0.6 T 13-10-2018 IPR000014 PAS domain MADE_1009115 dff11565160e57a672b30c6b63f18533 252 Gene3D G3DSA:3.30.70.1230 24 143 5.6E-6 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1009115 dff11565160e57a672b30c6b63f18533 252 SUPERFAMILY SSF55073 47 124 2.75E-5 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 Gene3D G3DSA:1.10.10.10 3 93 2.8E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 Pfam PF03466 LysR substrate binding domain 92 292 5.5E-30 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 SUPERFAMILY SSF46785 4 112 5.68E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 SUPERFAMILY SSF53850 92 293 3.41E-32 T 13-10-2018 MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.4E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.4E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.4E-9 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.0E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1009840 a9d868e2adaeca95c3669858e31aecc5 294 Gene3D G3DSA:3.40.190.290 94 294 9.9E-36 T 13-10-2018 MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 414 553 1.4E-16 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 Gene3D G3DSA:3.40.50.1220 224 373 1.1E-24 T 13-10-2018 MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 Gene3D G3DSA:3.40.50.970 10 210 2.2E-32 T 13-10-2018 MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 25 204 2.1E-21 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 SUPERFAMILY SSF52518 384 566 5.08E-27 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 Gene3D G3DSA:3.40.50.970 379 579 1.5E-26 T 13-10-2018 MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 SUPERFAMILY SSF52518 20 207 4.22E-20 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 SUPERFAMILY SSF52467 189 354 1.81E-21 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MADE_1019370 182c5337f5c7c4ddeba913fe29916e2b 600 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 230 343 2.2E-14 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 SUPERFAMILY SSF55031 181 291 5.68E-30 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 Gene3D G3DSA:3.40.630.10 10 364 1.2E-124 T 13-10-2018 MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 Gene3D G3DSA:3.30.70.360 181 294 1.2E-124 T 13-10-2018 MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 375 7.9E-167 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 SUPERFAMILY SSF53187 4 376 2.62E-63 T 13-10-2018 MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 Pfam PF07687 Peptidase dimerisation domain 177 283 9.0E-23 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 Pfam PF01546 Peptidase family M20/M25/M40 64 373 4.0E-44 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 MADE_1007790 c369fb69b29e36d35ddfefa75cf2c9d0 378 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 377 51.193 T 13-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 MADE_1015660 eb0dd1d9402c5ad0f618248f59055e0c 109 Gene3D G3DSA:1.10.3730.20 1 107 3.2E-27 T 13-10-2018 MADE_1015660 eb0dd1d9402c5ad0f618248f59055e0c 109 SUPERFAMILY SSF103481 5 104 1.31E-16 T 13-10-2018 MADE_1015660 eb0dd1d9402c5ad0f618248f59055e0c 109 Pfam PF00893 Small Multidrug Resistance protein 1 93 6.0E-23 T 13-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MADE_1005570 fd4fbb6898db17eb2de32d3614a3422f 831 Pfam PF13700 Domain of unknown function (DUF4158) 9 173 1.1E-30 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 MADE_1005570 fd4fbb6898db17eb2de32d3614a3422f 831 Pfam PF01526 Tn3 transposase DDE domain 581 831 7.4E-71 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 Pfam PF00106 short chain dehydrogenase 2 181 4.1E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 6.7E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 6.7E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 SUPERFAMILY SSF51735 2 219 3.95E-63 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 Gene3D G3DSA:3.40.50.720 1 219 2.9E-56 T 13-10-2018 MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.4E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.4E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 1.4E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009425 1a283ac4f3c1f1ccc774e83d944c40a5 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.4E-17 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013830 7c5d90ae0523344ba54d47a927d52008 648 SUPERFAMILY SSF53756 16 322 8.16E-7 T 13-10-2018 MADE_1013830 7c5d90ae0523344ba54d47a927d52008 648 Pfam PF13692 Glycosyl transferases group 1 221 322 5.1E-7 T 13-10-2018 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Gene3D G3DSA:3.30.310.50 403 485 2.0E-27 T 13-10-2018 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 SUPERFAMILY SSF53738 182 290 2.24E-26 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 407 484 2.3E-9 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 199 218 9.9E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 9.9E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 267 282 9.9E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 251 9.9E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Gene3D G3DSA:3.40.120.10 284 401 1.1E-31 T 13-10-2018 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 93 102 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 184 287 1.2E-19 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 292 401 6.6E-22 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Gene3D G3DSA:3.40.120.10 201 283 7.9E-29 T 13-10-2018 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 SUPERFAMILY SSF55957 403 485 7.72E-19 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Gene3D G3DSA:3.40.120.10 3 145 2.0E-49 T 13-10-2018 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 SUPERFAMILY SSF53738 292 396 1.96E-28 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 SUPERFAMILY SSF53738 7 123 8.83E-34 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1013920 91a2558f74b7cbddc1a8c77ff703e36a 486 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 134 5.1E-32 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001022845 fba69bfee33bda138aeabfe71c05d09f 277 SUPERFAMILY SSF56235 2 251 2.22E-47 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_000001022845 fba69bfee33bda138aeabfe71c05d09f 277 Pfam PF13230 Glutamine amidotransferases class-II 2 266 2.2E-107 T 13-10-2018 IPR026869 Putative glutamine amidotransferase type 2 MADE_000001022845 fba69bfee33bda138aeabfe71c05d09f 277 Gene3D G3DSA:3.60.20.10 1 257 1.1E-93 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1015400 c1517bc24fbc3073341fd37b10565aef 111 SUPERFAMILY SSF55068 7 98 6.02E-20 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1015400 c1517bc24fbc3073341fd37b10565aef 111 Pfam PF01625 Peptide methionine sulfoxide reductase 7 86 3.0E-13 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1015400 c1517bc24fbc3073341fd37b10565aef 111 Gene3D G3DSA:3.30.1060.10 5 91 1.8E-13 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 Pfam PF00581 Rhodanese-like domain 44 125 1.1E-7 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 Pfam PF00581 Rhodanese-like domain 156 265 3.8E-10 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 Gene3D G3DSA:3.40.250.10 153 275 2.5E-37 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 SUPERFAMILY SSF52821 2 143 1.83E-27 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 SMART SM00450 20 129 7.8E-7 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 SMART SM00450 151 270 1.1E-14 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 SUPERFAMILY SSF52821 161 275 3.67E-32 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 ProSitePatterns PS00683 Rhodanese C-terminal signature. 254 264 - T 13-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 MADE_1010510 cd4ec1297fd8bd92078dc689f5ceece8 276 Gene3D G3DSA:3.40.250.10 2 145 9.7E-33 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1018065 d7750e8388194a9634202384c168b7a4 214 SUPERFAMILY SSF81901 74 191 9.29E-19 T 13-10-2018 MADE_1018065 d7750e8388194a9634202384c168b7a4 214 Gene3D G3DSA:1.25.40.10 25 214 2.9E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1018065 d7750e8388194a9634202384c168b7a4 214 SMART SM00671 112 147 1.1E-5 T 13-10-2018 IPR006597 Sel1-like repeat MADE_1018065 d7750e8388194a9634202384c168b7a4 214 SMART SM00671 148 183 58.0 T 13-10-2018 IPR006597 Sel1-like repeat MADE_1018065 d7750e8388194a9634202384c168b7a4 214 SMART SM00671 76 111 27.0 T 13-10-2018 IPR006597 Sel1-like repeat MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 Pfam PF14559 Tetratricopeptide repeat 312 381 4.3E-6 T 13-10-2018 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 Gene3D G3DSA:1.25.40.10 192 294 1.1E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 SMART SM00028 268 301 330.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 SMART SM00028 302 335 38.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 SMART SM00028 200 233 36.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 SMART SM00028 336 369 0.51 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 SMART SM00028 234 267 0.013 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 Gene3D G3DSA:1.25.40.10 295 385 7.9E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 SUPERFAMILY SSF48452 200 369 2.85E-27 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001023065 d4b9261ffb16299fcb63078c7b206dd0 385 Pfam PF13176 Tetratricopeptide repeat 236 266 0.0036 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 9 205 36.718 T 13-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 118 203 1.4E-15 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 57 106 5.0E-18 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 34 107 3.3E-31 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 114 200 18.746 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 117 200 1.5E-29 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 Gene3D G3DSA:3.10.20.400 3 98 4.6E-34 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 Gene3D G3DSA:1.10.287.1080 114 205 4.0E-29 T 13-10-2018 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 SUPERFAMILY SSF101386 116 205 7.29E-25 T 13-10-2018 MADE_000001022230 a7e4d4eead45ef4138fc1832207acf5b 205 SUPERFAMILY SSF141734 9 120 1.44E-44 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MADE_1012240 90f32deadd0ae10ef36ac6896d8d1c1d 221 Gene3D G3DSA:1.10.238.10 22 78 8.3E-7 T 13-10-2018 MADE_1012240 90f32deadd0ae10ef36ac6896d8d1c1d 221 Gene3D G3DSA:1.10.238.10 159 218 7.2E-7 T 13-10-2018 MADE_1012240 90f32deadd0ae10ef36ac6896d8d1c1d 221 SUPERFAMILY SSF47473 22 211 1.64E-13 T 13-10-2018 IPR011992 EF-hand domain pair MADE_1012240 90f32deadd0ae10ef36ac6896d8d1c1d 221 Pfam PF13202 EF hand 165 182 0.025 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_1012240 90f32deadd0ae10ef36ac6896d8d1c1d 221 Pfam PF13202 EF hand 28 46 0.11 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_1013810 7f29f754f94b735ef3b7e148b0cc83aa 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 175 9.4E-74 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MADE_1013810 7f29f754f94b735ef3b7e148b0cc83aa 181 SUPERFAMILY SSF51182 1 178 1.19E-77 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1013810 7f29f754f94b735ef3b7e148b0cc83aa 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 5.7E-83 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MADE_1013810 7f29f754f94b735ef3b7e148b0cc83aa 181 Gene3D G3DSA:2.60.120.10 1 180 3.5E-74 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1013810 7f29f754f94b735ef3b7e148b0cc83aa 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 179 4.0E-69 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 145 1.6E-45 T 13-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 SUPERFAMILY SSF56327 146 311 1.18E-41 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 Hamap MF_01516 Malate dehydrogenase [mdh]. 1 311 54.286 T 13-10-2018 IPR023958 Malate dehydrogenase, type 1, bacterial GO:0006099|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 PIRSF PIRSF000102 1 300 8.9E-63 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 310 2.2E-46 T 13-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 SUPERFAMILY SSF51735 1 145 7.93E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 TIGRFAM TIGR01772 MDH_euk_gproteo: malate dehydrogenase, NAD-dependent 2 311 3.5E-131 T 13-10-2018 IPR010097 Malate dehydrogenase, type 1 GO:0006099|GO:0030060 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263|Reactome: R-HSA-71403 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 146 158 - T 13-10-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 Gene3D G3DSA:3.90.110.10 147 312 3.5E-52 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 MADE_000001023020 c1886d1ca964feac41a5a5e393f81e82 312 Gene3D G3DSA:3.40.50.720 1 146 1.2E-63 T 13-10-2018 MADE_1000265 260ca2950d6586fbb84fa7e580b06b5d 78 Gene3D G3DSA:2.30.170.40 2 78 7.8E-33 T 13-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1000265 260ca2950d6586fbb84fa7e580b06b5d 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.519 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1000265 260ca2950d6586fbb84fa7e580b06b5d 78 SUPERFAMILY SSF143800 2 77 1.55E-29 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1000265 260ca2950d6586fbb84fa7e580b06b5d 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 4.8E-27 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1000265 260ca2950d6586fbb84fa7e580b06b5d 78 Pfam PF00830 Ribosomal L28 family 3 62 1.1E-25 T 13-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013575 7ba26624975a9993d75c0afe5e7697c8 391 Gene3D G3DSA:3.40.50.720 8 172 1.1E-37 T 13-10-2018 MADE_1013575 7ba26624975a9993d75c0afe5e7697c8 391 SUPERFAMILY SSF51735 9 162 7.48E-15 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013575 7ba26624975a9993d75c0afe5e7697c8 391 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 9 137 4.6E-17 T 13-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 Gene3D G3DSA:1.20.200.10 118 446 5.0E-156 T 13-10-2018 MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 2.1E-51 T 13-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 7.4E-18 T 13-10-2018 IPR000362 Fumarate lyase family MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 7.4E-18 T 13-10-2018 IPR000362 Fumarate lyase family MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 7.4E-18 T 13-10-2018 IPR000362 Fumarate lyase family MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 7.4E-18 T 13-10-2018 IPR000362 Fumarate lyase family MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 455 1.6E-140 T 13-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 Gene3D G3DSA:1.10.40.30 382 445 5.0E-156 T 13-10-2018 MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 Gene3D G3DSA:1.10.275.10 1 117 4.0E-50 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 Pfam PF00206 Lyase 14 312 9.3E-72 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal MADE_000001021690 dd01f8a37071c6b6cfdc0a0563d42c04 455 SUPERFAMILY SSF48557 4 446 5.5E-107 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Pfam PF00563 EAL domain 1260 1493 3.4E-69 T 13-10-2018 IPR001633 EAL domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 959 1081 4.4E-16 T 13-10-2018 IPR000014 PAS domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SUPERFAMILY SSF141868 1257 1508 2.22E-85 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SMART SM00091 963 1030 0.0068 T 13-10-2018 IPR000014 PAS domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Pfam PF08447 PAS fold 875 948 6.3E-12 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SMART SM00052 1252 1498 1.9E-105 T 13-10-2018 IPR001633 EAL domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Gene3D G3DSA:3.30.450.20 832 950 1.2E-17 T 13-10-2018 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Gene3D G3DSA:2.60.40.10 676 807 3.2E-26 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Gene3D G3DSA:3.30.70.270 1080 1255 1.1E-56 T 13-10-2018 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1085 1237 3.0E-43 T 13-10-2018 IPR000160 GGDEF domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Gene3D G3DSA:3.20.20.450 1256 1508 1.9E-95 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SMART SM00086 1032 1074 7.8E-6 T 13-10-2018 IPR001610 PAC motif MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SMART SM00086 912 955 110.0 T 13-10-2018 IPR001610 PAC motif MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Gene3D G3DSA:2.130.10.10 31 351 2.0E-56 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Gene3D G3DSA:3.30.450.20 957 1077 3.2E-26 T 13-10-2018 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Pfam PF13426 PAS domain 974 1072 2.3E-13 T 13-10-2018 IPR000014 PAS domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SUPERFAMILY SSF63829 87 291 3.11E-13 T 13-10-2018 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SUPERFAMILY SSF55073 1090 1244 8.63E-46 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1083 1240 1.3E-34 T 13-10-2018 IPR000160 GGDEF domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SUPERFAMILY SSF55785 969 1072 7.68E-20 T 13-10-2018 IPR035965 PAS domain superfamily MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SUPERFAMILY SSF63829 331 573 8.5E-9 T 13-10-2018 MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Pfam PF07494 Two component regulator propeller 87 109 1.8E-4 T 13-10-2018 IPR011110 Two component regulator propeller MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Pfam PF07495 Y_Y_Y domain 735 795 2.8E-13 T 13-10-2018 IPR011123 Two component regulator three Y MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SUPERFAMILY SSF55785 866 958 9.42E-9 T 13-10-2018 IPR035965 PAS domain superfamily MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 SMART SM00267 1074 1242 2.9E-56 T 13-10-2018 IPR000160 GGDEF domain MADE_000001020950 4b6c6d68faaf307ecb8f729738caacbe 1518 Gene3D G3DSA:2.130.10.10 419 661 8.7E-16 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1013300 551650fdeecd926d1face4fef00c4b73 283 Gene3D G3DSA:3.20.20.150 3 279 5.4E-84 T 13-10-2018 MADE_1013300 551650fdeecd926d1face4fef00c4b73 283 Pfam PF05114 Protein of unknown function (DUF692) 6 267 1.8E-99 T 13-10-2018 IPR007801 Uncharacterised protein family UPF0276 MADE_1013300 551650fdeecd926d1face4fef00c4b73 283 SUPERFAMILY SSF51658 27 205 3.3E-8 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily MADE_1008345 1fb04a11797b4bb8a6dad0209b3a891f 391 Pfam PF10442 FIST C domain 253 371 5.1E-16 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MADE_1008345 1fb04a11797b4bb8a6dad0209b3a891f 391 SMART SM01204 225 372 1.5E-25 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 MADE_1008345 1fb04a11797b4bb8a6dad0209b3a891f 391 SMART SM00897 28 224 1.5E-11 T 13-10-2018 IPR013702 FIST domain, N-terminal MADE_1008345 1fb04a11797b4bb8a6dad0209b3a891f 391 Pfam PF08495 FIST N domain 86 222 3.2E-15 T 13-10-2018 IPR013702 FIST domain, N-terminal MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 TIGRFAM TIGR00433 bioB: biotin synthase 26 321 8.2E-126 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 SUPERFAMILY SSF102114 16 321 9.68E-93 T 13-10-2018 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 SMART SM00729 54 266 4.7E-38 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 Pfam PF04055 Radical SAM superfamily 61 214 8.9E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 Gene3D G3DSA:3.20.20.70 15 326 5.7E-132 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 SMART SM00876 231 323 3.0E-46 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 231 321 1.7E-20 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 PIRSF PIRSF001619 3 330 3.5E-138 T 13-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MADE_1007255 d00f419ffa15d55a10709c56be8be63c 374 Hamap MF_01694 Biotin synthase [bioB]. 16 324 42.498 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MADE_1013240 d3de1ff422e030df2a6e5f5e9f512f84 864 Gene3D G3DSA:2.170.130.10 33 175 1.9E-36 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1013240 d3de1ff422e030df2a6e5f5e9f512f84 864 SUPERFAMILY SSF56935 30 864 1.6E-108 T 13-10-2018 MADE_1013240 d3de1ff422e030df2a6e5f5e9f512f84 864 Gene3D G3DSA:2.40.170.20 294 864 1.1E-63 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1013240 d3de1ff422e030df2a6e5f5e9f512f84 864 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 171 1.7E-23 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1013240 d3de1ff422e030df2a6e5f5e9f512f84 864 Pfam PF00593 TonB dependent receptor 337 863 5.7E-51 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_000001022885 bc3cccd8353b295167d8c16d787bfa6f 176 SMART SM00903 26 171 9.4E-50 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MADE_000001022885 bc3cccd8353b295167d8c16d787bfa6f 176 Gene3D G3DSA:2.30.110.10 4 175 2.6E-42 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_000001022885 bc3cccd8353b295167d8c16d787bfa6f 176 SUPERFAMILY SSF50475 16 172 6.38E-42 T 13-10-2018 MADE_000001022885 bc3cccd8353b295167d8c16d787bfa6f 176 Pfam PF01613 Flavin reductase like domain 26 171 6.9E-31 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 39 466 9.4E-103 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 37 469 61.575 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 38 466 7.4E-179 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 173 193 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 Gene3D G3DSA:3.80.30.20 167 408 5.9E-74 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 Gene3D G3DSA:3.40.50.12160 37 162 2.0E-30 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 Gene3D G3DSA:2.40.50.140 409 477 2.2E-15 T 13-10-2018 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 Pfam PF00919 Uncharacterized protein family UPF0004 38 129 9.1E-22 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 SUPERFAMILY SSF102114 133 399 1.96E-54 T 13-10-2018 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 Pfam PF04055 Radical SAM superfamily 175 352 1.4E-30 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1009430 c9447352102c4bab2e33fcccd639fae6 485 SMART SM00729 169 394 7.4E-55 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 Pfam PF00206 Lyase 12 337 2.5E-91 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 Gene3D G3DSA:1.20.200.10 134 400 4.0E-94 T 13-10-2018 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 SUPERFAMILY SSF48557 2 451 5.97E-132 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 PRINTS PR00149 Fumarate lyase superfamily signature 266 293 1.6E-29 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 PRINTS PR00149 Fumarate lyase superfamily signature 129 147 1.6E-29 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 PRINTS PR00149 Fumarate lyase superfamily signature 175 193 1.6E-29 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 PRINTS PR00149 Fumarate lyase superfamily signature 312 328 1.6E-29 T 13-10-2018 IPR000362 Fumarate lyase family MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 Pfam PF10415 Fumarase C C-terminus 403 456 1.3E-18 T 13-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 457 72.225 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 ProSitePatterns PS00163 Fumarate lyases signature. 312 321 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 Gene3D G3DSA:1.10.40.30 403 457 6.7E-18 T 13-10-2018 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 PRINTS PR00145 Argininosuccinate lyase family signature 312 328 1.9E-6 T 13-10-2018 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 PRINTS PR00145 Argininosuccinate lyase family signature 128 150 1.9E-6 T 13-10-2018 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 PRINTS PR00145 Argininosuccinate lyase family signature 170 190 1.9E-6 T 13-10-2018 MADE_1015925 174af8e24fe1e5ab2403f8eca535afd0 457 Gene3D G3DSA:1.10.275.10 5 133 1.1E-50 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal MADE_1013385 75545f571c0d36f26b8ddb2d8cf0c7bd 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 66 373 1.2E-69 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1013385 75545f571c0d36f26b8ddb2d8cf0c7bd 376 Gene3D G3DSA:1.10.287.470 125 184 4.3E-70 T 13-10-2018 MADE_1013385 75545f571c0d36f26b8ddb2d8cf0c7bd 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 88 292 1.0E-25 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1013385 75545f571c0d36f26b8ddb2d8cf0c7bd 376 Gene3D G3DSA:2.40.420.20 304 371 4.3E-70 T 13-10-2018 MADE_1013385 75545f571c0d36f26b8ddb2d8cf0c7bd 376 Gene3D G3DSA:2.40.50.100 90 220 4.3E-70 T 13-10-2018 MADE_1013385 75545f571c0d36f26b8ddb2d8cf0c7bd 376 Gene3D G3DSA:2.40.30.170 77 303 4.3E-70 T 13-10-2018 MADE_1013385 75545f571c0d36f26b8ddb2d8cf0c7bd 376 SUPERFAMILY SSF111369 79 299 1.44E-38 T 13-10-2018 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 SUPERFAMILY SSF52374 6 331 2.64E-99 T 13-10-2018 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 4.7E-29 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 143 164 4.7E-29 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 196 206 4.7E-29 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 17 33 4.7E-29 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 13 22 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 Pfam PF00579 tRNA synthetases class I (W and Y) 4 286 2.4E-81 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 Gene3D G3DSA:3.40.50.620 7 330 2.9E-140 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 Gene3D G3DSA:1.10.240.10 187 299 2.9E-140 T 13-10-2018 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 4 332 41.659 T 13-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 MADE_1002525 5b1b1ee4911dc5215500b1703074d584 335 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 331 2.9E-115 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 MADE_000001021610 7538f07e7e8a873985b3141d673a91d1 224 SUPERFAMILY SSF56784 6 207 9.65E-48 T 13-10-2018 IPR036412 HAD-like superfamily MADE_000001021610 7538f07e7e8a873985b3141d673a91d1 224 Gene3D G3DSA:1.10.150.240 21 87 7.5E-53 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MADE_000001021610 7538f07e7e8a873985b3141d673a91d1 224 Gene3D G3DSA:3.40.50.1000 9 194 7.5E-53 T 13-10-2018 IPR023214 HAD superfamily MADE_000001021610 7538f07e7e8a873985b3141d673a91d1 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 184 9.1E-26 T 13-10-2018 MADE_000001021610 7538f07e7e8a873985b3141d673a91d1 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 9 185 2.7E-18 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 319 3.3E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 SMART SM00387 363 488 4.8E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 Gene3D G3DSA:1.10.287.130 218 320 4.2E-14 T 13-10-2018 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 Gene3D G3DSA:1.20.1440.210 47 174 3.0E-21 T 13-10-2018 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 SMART SM00388 254 322 2.6E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 Pfam PF05227 CHASE3 domain 47 171 6.0E-19 T 13-10-2018 IPR007891 CHASE3 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 SUPERFAMILY SSF55874 312 486 4.98E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 Gene3D G3DSA:3.30.565.10 324 489 2.3E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 SUPERFAMILY SSF47384 240 320 8.63E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 363 486 1.5E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 466 3.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 443 3.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 485 3.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011555 f6f722d7d7e92bbf436df8e04ab2dc23 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 429 3.1E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 Gene3D G3DSA:3.90.190.20 312 448 3.3E-30 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 SUPERFAMILY SSF53244 309 446 1.57E-39 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 Pfam PF01225 Mur ligase family, catalytic domain 2 95 4.5E-16 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 447 58.429 T 13-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 309 357 7.1E-11 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 Pfam PF08245 Mur ligase middle domain 109 289 1.8E-20 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 Gene3D G3DSA:3.40.1190.10 91 311 1.4E-54 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 SUPERFAMILY SSF51984 1 90 1.57E-23 T 13-10-2018 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 SUPERFAMILY SSF53623 94 306 1.7E-49 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 446 5.3E-230 T 13-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 MADE_1001050 f9f29c193073cfaf42ef867ed0a37602 452 Gene3D G3DSA:3.40.50.720 1 90 2.5E-34 T 13-10-2018 MADE_1001150 5df9225ad5d75773d2360262bdaac9ea 196 Pfam PF00436 Single-strand binding protein family 6 109 1.3E-44 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 MADE_1001150 5df9225ad5d75773d2360262bdaac9ea 196 SUPERFAMILY SSF50249 5 196 1.03E-56 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1001150 5df9225ad5d75773d2360262bdaac9ea 196 Hamap MF_00984 Single-stranded DNA-binding protein. 6 113 39.061 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MADE_1001150 5df9225ad5d75773d2360262bdaac9ea 196 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 4 196 3.0E-63 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 MADE_1001150 5df9225ad5d75773d2360262bdaac9ea 196 Gene3D G3DSA:2.40.50.140 2 121 2.0E-49 T 13-10-2018 MADE_1010335 7c182cf7b29e59182157d118f16e4337 412 Gene3D G3DSA:1.10.443.10 195 411 1.8E-18 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1010335 7c182cf7b29e59182157d118f16e4337 412 Pfam PF00589 Phage integrase family 201 398 7.3E-13 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1010335 7c182cf7b29e59182157d118f16e4337 412 SUPERFAMILY SSF56349 43 398 3.53E-27 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 3.7E-260 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 Pfam PF13522 Glutamine amidotransferase domain 54 182 2.5E-19 T 13-10-2018 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 Gene3D G3DSA:3.40.50.10490 448 595 3.8E-150 T 13-10-2018 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 40.75 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 Gene3D G3DSA:3.60.20.10 2 242 3.3E-77 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 Pfam PF01380 SIS domain 291 419 2.2E-34 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 Pfam PF01380 SIS domain 463 592 6.5E-27 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 SUPERFAMILY SSF56235 2 235 1.63E-73 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 Gene3D G3DSA:3.40.50.10490 250 609 3.8E-150 T 13-10-2018 MADE_1019455 08b0e6e459345bf92b66ecfd467571dc 610 SUPERFAMILY SSF53697 246 610 1.39E-113 T 13-10-2018 MADE_1011690 9f9bd0f064b88b4bb7a60d5d13df936d 317 Pfam PF02685 Glucokinase 6 313 6.6E-108 T 13-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MADE_1011690 9f9bd0f064b88b4bb7a60d5d13df936d 317 Gene3D G3DSA:3.30.420.40 6 308 2.3E-99 T 13-10-2018 MADE_1011690 9f9bd0f064b88b4bb7a60d5d13df936d 317 Gene3D G3DSA:3.40.367.20 98 297 2.3E-99 T 13-10-2018 MADE_1011690 9f9bd0f064b88b4bb7a60d5d13df936d 317 TIGRFAM TIGR00749 glk: glucokinase 6 308 2.2E-91 T 13-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MADE_1011690 9f9bd0f064b88b4bb7a60d5d13df936d 317 SUPERFAMILY SSF53067 6 313 9.43E-61 T 13-10-2018 MADE_1011690 9f9bd0f064b88b4bb7a60d5d13df936d 317 Hamap MF_00524 Glucokinase [glk]. 3 314 32.438 T 13-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 MADE_000001022440 129a6492773b5abf36412b77da794216 550 TIGRFAM TIGR01810 betA: choline dehydrogenase 5 532 3.0E-235 T 13-10-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 MADE_000001022440 129a6492773b5abf36412b77da794216 550 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 81 104 - T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_000001022440 129a6492773b5abf36412b77da794216 550 Gene3D G3DSA:3.30.410.40 150 469 2.1E-181 T 13-10-2018 MADE_000001022440 129a6492773b5abf36412b77da794216 550 PIRSF PIRSF000137 1 536 9.4E-156 T 13-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_000001022440 129a6492773b5abf36412b77da794216 550 SUPERFAMILY SSF54373 290 472 3.63E-61 T 13-10-2018 MADE_000001022440 129a6492773b5abf36412b77da794216 550 Gene3D G3DSA:3.50.50.60 4 526 2.1E-181 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_000001022440 129a6492773b5abf36412b77da794216 550 SUPERFAMILY SSF51905 3 530 4.44E-87 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_000001022440 129a6492773b5abf36412b77da794216 550 Gene3D G3DSA:4.10.450.10 37 196 2.1E-181 T 13-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 MADE_000001022440 129a6492773b5abf36412b77da794216 550 Pfam PF00732 GMC oxidoreductase 4 295 2.1E-96 T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_000001022440 129a6492773b5abf36412b77da794216 550 Gene3D G3DSA:1.10.1220.110 96 149 2.1E-181 T 13-10-2018 MADE_000001022440 129a6492773b5abf36412b77da794216 550 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 13-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 MADE_000001022440 129a6492773b5abf36412b77da794216 550 Pfam PF05199 GMC oxidoreductase 386 522 1.1E-40 T 13-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Gene3D G3DSA:3.20.19.10 162 361 5.0E-72 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 ProSitePatterns PS00450 Aconitase family signature 1. 702 719 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Gene3D G3DSA:3.30.499.10 402 529 8.1E-149 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Pfam PF00330 Aconitase family (aconitate hydratase) 472 818 7.4E-41 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Pfam PF06434 Aconitate hydratase 2 N-terminus 169 382 1.9E-93 T 13-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 853 0.0 T 13-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 PIRSF PIRSF036687 1 859 0.0 T 13-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 SUPERFAMILY SSF74778 2 159 6.8E-66 T 13-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 SUPERFAMILY SSF53732 379 856 1.31E-147 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Gene3D G3DSA:3.40.1060.10 385 681 8.1E-149 T 13-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Gene3D G3DSA:1.25.40.310 1 160 3.4E-68 T 13-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Gene3D G3DSA:3.30.499.10 683 864 8.6E-65 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 Pfam PF11791 Aconitate B N-terminal domain 4 156 1.8E-64 T 13-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003950 78ac4ddc50f300f330c01d76ff89227c 870 SUPERFAMILY SSF52016 164 372 1.41E-67 T 13-10-2018 MADE_1019255 7a91689841caaf40922ec214a32525e7 264 SUPERFAMILY SSF54534 100 206 2.16E-22 T 13-10-2018 MADE_1019255 7a91689841caaf40922ec214a32525e7 264 Pfam PF00639 PPIC-type PPIASE domain 114 206 1.6E-19 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MADE_1019255 7a91689841caaf40922ec214a32525e7 264 SUPERFAMILY SSF109998 7 123 2.55E-7 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily MADE_1019255 7a91689841caaf40922ec214a32525e7 264 Gene3D G3DSA:3.10.50.40 109 210 7.5E-21 T 13-10-2018 MADE_1002695 d827238dc936ec3c7300836468a43876 154 SUPERFAMILY SSF75217 2 152 5.1E-45 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_1002695 d827238dc936ec3c7300836468a43876 154 Gene3D G3DSA:3.40.1280.10 1 154 6.8E-67 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_1002695 d827238dc936ec3c7300836468a43876 154 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.4E-34 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MADE_1002695 d827238dc936ec3c7300836468a43876 154 PIRSF PIRSF029256 1 154 3.8E-66 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MADE_1002695 d827238dc936ec3c7300836468a43876 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 32.797 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MADE_1002695 d827238dc936ec3c7300836468a43876 154 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 153 1.4E-63 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 MADE_1013785 0bcab9ad5bb6972f4ef2270c042d35ba 132 SUPERFAMILY SSF81273 88 131 7.85E-10 T 13-10-2018 MADE_1013785 0bcab9ad5bb6972f4ef2270c042d35ba 132 Gene3D G3DSA:4.10.430.10 88 132 1.8E-18 T 13-10-2018 IPR037150 Histone-like protein H-NS, C-terminal domain superfamily GO:0003677 MADE_1013785 0bcab9ad5bb6972f4ef2270c042d35ba 132 SMART SM00528 84 131 3.8E-14 T 13-10-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 MADE_1013785 0bcab9ad5bb6972f4ef2270c042d35ba 132 SUPERFAMILY SSF81273 2 58 5.49E-12 T 13-10-2018 MADE_1013785 0bcab9ad5bb6972f4ef2270c042d35ba 132 PIRSF PIRSF002096 1 131 9.7E-43 T 13-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 MADE_1013785 0bcab9ad5bb6972f4ef2270c042d35ba 132 Gene3D G3DSA:1.10.287.1050 1 81 2.6E-16 T 13-10-2018 IPR027454 Histone-like protein H-NS, N-terminal GO:0046983 MADE_1013785 0bcab9ad5bb6972f4ef2270c042d35ba 132 Pfam PF00816 H-NS histone family 37 125 3.0E-15 T 13-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 MADE_1009455 9f04a290139e3b52f6d82f84c6c3cd60 287 Gene3D G3DSA:2.60.120.10 148 255 4.4E-97 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1009455 9f04a290139e3b52f6d82f84c6c3cd60 287 Pfam PF05726 Pirin C-terminal cupin domain 181 284 6.1E-26 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 MADE_1009455 9f04a290139e3b52f6d82f84c6c3cd60 287 Pfam PF02678 Pirin 27 126 1.7E-36 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 MADE_1009455 9f04a290139e3b52f6d82f84c6c3cd60 287 PIRSF PIRSF006232 7 287 1.8E-93 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 MADE_1009455 9f04a290139e3b52f6d82f84c6c3cd60 287 SUPERFAMILY SSF51182 10 283 1.24E-84 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1009455 9f04a290139e3b52f6d82f84c6c3cd60 287 Gene3D G3DSA:2.60.120.10 22 281 4.4E-97 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_000001021810 2a7f7c66814ee0febb4c7cf999c6eff6 371 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 14 369 27.808 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_000001021810 2a7f7c66814ee0febb4c7cf999c6eff6 371 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 20 366 1.1E-131 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_000001021810 2a7f7c66814ee0febb4c7cf999c6eff6 371 Pfam PF01098 Cell cycle protein 23 367 1.8E-106 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1004690 2b5f9f815ea0308b58fda41b5a6403d3 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 3 201 41.54 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MADE_1004690 2b5f9f815ea0308b58fda41b5a6403d3 201 Pfam PF00694 Aconitase C-terminal domain 5 127 1.6E-34 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 MADE_1004690 2b5f9f815ea0308b58fda41b5a6403d3 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 5 190 4.1E-79 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 MADE_1004690 2b5f9f815ea0308b58fda41b5a6403d3 201 Gene3D G3DSA:3.20.19.10 1 182 1.1E-74 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MADE_1004690 2b5f9f815ea0308b58fda41b5a6403d3 201 SUPERFAMILY SSF52016 4 196 1.51E-56 T 13-10-2018 MADE_1001775 01ab3d8ba0641130b1fb4d7d98996f22 135 SUPERFAMILY SSF53098 1 134 8.35E-26 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1001775 01ab3d8ba0641130b1fb4d7d98996f22 135 Gene3D G3DSA:3.30.420.10 1 134 4.6E-15 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1001775 01ab3d8ba0641130b1fb4d7d98996f22 135 Pfam PF00665 Integrase core domain 1 104 1.7E-18 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1001825 d8a4e81378eb2bbaba265d2eed19f14d 71 Pfam PF13127 Protein of unknown function (DUF3955) 7 64 1.5E-13 T 13-10-2018 IPR025016 Protein of unknown function DUF3955 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 278 9.0E-133 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 279 36.687 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 141 7.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 249 258 7.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 161 179 7.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 198 215 7.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 227 238 7.6E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 Gene3D G3DSA:3.90.226.10 23 281 1.0E-86 T 13-10-2018 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 Pfam PF01039 Carboxyl transferase domain 99 238 9.8E-16 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MADE_1011895 53c8022ec31f5d4e9a52cca273ea47d8 281 SUPERFAMILY SSF52096 23 278 1.12E-87 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1004250 00e3652b327f5a56dfca7932b451b79d 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 417 2.8E-179 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1004250 00e3652b327f5a56dfca7932b451b79d 420 Gene3D G3DSA:3.65.10.10 6 415 1.6E-168 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MADE_1004250 00e3652b327f5a56dfca7932b451b79d 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 44.648 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 MADE_1004250 00e3652b327f5a56dfca7932b451b79d 420 Gene3D G3DSA:3.65.10.10 21 230 1.6E-168 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MADE_1004250 00e3652b327f5a56dfca7932b451b79d 420 SUPERFAMILY SSF55205 2 419 1.39E-143 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MADE_1004250 00e3652b327f5a56dfca7932b451b79d 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 8.1E-118 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MADE_1014285 c49153b0e9cf74e6c2722bc65a14f7a3 102 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 101 2.4E-43 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014285 c49153b0e9cf74e6c2722bc65a14f7a3 102 SUPERFAMILY SSF51278 1 101 7.19E-45 T 13-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014285 c49153b0e9cf74e6c2722bc65a14f7a3 102 Gene3D G3DSA:2.10.150.10 1 102 6.2E-45 T 13-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014285 c49153b0e9cf74e6c2722bc65a14f7a3 102 Pfam PF00699 Urease beta subunit 3 99 1.8E-43 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014285 c49153b0e9cf74e6c2722bc65a14f7a3 102 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 30.258 T 13-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_000001021990 483bce8ffd03033b0901c0d88596d0bc 65 Gene3D G3DSA:2.180.10.10 2 65 4.9E-13 T 13-10-2018 MADE_000001021990 483bce8ffd03033b0901c0d88596d0bc 65 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 17 64 2.1E-12 T 13-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 1227 1268 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Pfam PF00512 His Kinase A (phospho-acceptor) domain 787 841 9.3E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SUPERFAMILY SSF47384 778 841 4.12E-8 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Gene3D G3DSA:3.30.565.10 861 1002 1.8E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Gene3D G3DSA:3.40.50.2300 1006 1153 7.5E-30 T 13-10-2018 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Pfam PF12833 Helix-turn-helix domain 1197 1273 9.7E-14 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Pfam PF00072 Response regulator receiver domain 1025 1134 8.1E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SMART SM00448 1022 1134 2.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SUPERFAMILY SSF55874 863 999 1.27E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Gene3D G3DSA:1.10.287.130 776 843 1.3E-10 T 13-10-2018 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Gene3D G3DSA:2.130.10.10 379 579 3.5E-5 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SMART SM00342 1190 1272 1.4E-11 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 896 999 1.2E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SUPERFAMILY SSF46689 1227 1275 1.03E-5 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SUPERFAMILY SSF52172 1020 1146 2.7E-29 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SMART SM00388 787 850 1.6E-4 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 PRINTS PR00344 Bacterial sensor protein C-terminal signature 948 958 8.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 PRINTS PR00344 Bacterial sensor protein C-terminal signature 961 979 8.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 PRINTS PR00344 Bacterial sensor protein C-terminal signature 985 998 8.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 PRINTS PR00344 Bacterial sensor protein C-terminal signature 930 944 8.4E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Gene3D G3DSA:2.130.10.10 42 284 4.5E-13 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SUPERFAMILY SSF63829 70 555 3.27E-5 T 13-10-2018 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 Gene3D G3DSA:1.10.10.60 1176 1273 2.6E-15 T 13-10-2018 MADE_1002070 bad23e5d4d06ea473b5d54794a54570f 1280 SMART SM00387 893 1001 2.5E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1010645 5388bb2a36bde4b1b09715a681ae08aa 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.2E-19 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1010645 5388bb2a36bde4b1b09715a681ae08aa 301 Pfam PF03466 LysR substrate binding domain 89 289 1.7E-38 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1010645 5388bb2a36bde4b1b09715a681ae08aa 301 SUPERFAMILY SSF46785 4 83 3.49E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1010645 5388bb2a36bde4b1b09715a681ae08aa 301 Gene3D G3DSA:3.40.190.290 91 294 1.1E-57 T 13-10-2018 MADE_1010645 5388bb2a36bde4b1b09715a681ae08aa 301 SUPERFAMILY SSF53850 90 297 3.57E-42 T 13-10-2018 MADE_1010645 5388bb2a36bde4b1b09715a681ae08aa 301 Gene3D G3DSA:1.10.10.10 3 89 4.0E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009100 87ec1f7eb047906719a3a77f5c68c53b 191 Pfam PF06055 Exopolysaccharide synthesis, ExoD 7 184 1.3E-51 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD MADE_1009100 87ec1f7eb047906719a3a77f5c68c53b 191 PIRSF PIRSF033239 1 191 8.0E-52 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 Pfam PF00842 Alanine racemase, C-terminal domain 232 354 2.3E-45 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 286 303 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 27 43 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 338 351 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 155 166 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 192 219 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 122 134 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 248 263 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 265 280 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 PRINTS PR00992 Alanine racemase signature 62 80 9.2E-58 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 SMART SM01005 232 356 2.2E-68 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 13-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 Pfam PF01168 Alanine racemase, N-terminal domain 9 217 1.6E-55 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 Gene3D G3DSA:3.20.20.10 11 217 2.3E-118 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 Gene3D G3DSA:2.40.37.10 9 351 2.3E-118 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 SUPERFAMILY SSF51419 9 228 2.47E-57 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 TIGRFAM TIGR00492 alr: alanine racemase 3 354 1.1E-101 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 Hamap MF_01201 Alanine racemase. 2 356 32.052 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1002985 f10bbb0f5c02dc4ed60613bb0bbebd09 358 SUPERFAMILY SSF50621 226 355 1.12E-48 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 MADE_1003390 a364f45bff2affeed171b5d3df1bc7e4 96 Hamap MF_00599 Cell division protein FtsB [ftsB]. 5 93 34.032 T 13-10-2018 IPR023081 Cell division protein FtsB MADE_1003390 a364f45bff2affeed171b5d3df1bc7e4 96 Pfam PF04977 Septum formation initiator 14 91 1.4E-25 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC MADE_1019575 691a2ad0b91cee8cc4478d8c054600b3 123 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 33 107 8.8E-14 T 13-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 MADE_1019575 691a2ad0b91cee8cc4478d8c054600b3 123 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 26 122 1.1E-32 T 13-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 Gene3D G3DSA:1.10.287.950 337 635 2.6E-41 T 13-10-2018 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 Gene3D G3DSA:1.10.287.950 28 336 2.5E-47 T 13-10-2018 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 SMART SM00283 351 626 8.4E-16 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 SMART SM00283 37 340 2.5E-30 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 442 591 1.4E-25 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 142 293 5.0E-31 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 SUPERFAMILY SSF58104 52 336 6.54E-47 T 13-10-2018 MADE_1015100 f9d88a2e04f60bca8834ad2a2e534a30 635 SUPERFAMILY SSF58104 352 633 4.12E-42 T 13-10-2018 MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 SMART SM00304 287 340 9.3E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 SMART SM00052 505 752 8.4E-99 T 13-10-2018 IPR001633 EAL domain MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 SMART SM00267 335 494 3.2E-7 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 SUPERFAMILY SSF55073 351 488 3.22E-15 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 SUPERFAMILY SSF141868 520 760 1.7E-80 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 344 477 1.0E-13 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 Gene3D G3DSA:3.20.20.450 507 761 5.4E-89 T 13-10-2018 IPR035919 EAL domain superfamily MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 SUPERFAMILY SSF158472 287 337 9.94E-6 T 13-10-2018 MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 Pfam PF00563 EAL domain 512 747 2.0E-69 T 13-10-2018 IPR001633 EAL domain MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 Gene3D G3DSA:3.30.70.270 343 506 4.3E-19 T 13-10-2018 MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 Pfam PF00990 Diguanylate cyclase, GGDEF domain 346 476 1.5E-13 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021915 20833110aa0d6bd6e6b5a384a8b72fb2 764 Gene3D G3DSA:1.20.1480.50 251 342 1.1E-10 T 13-10-2018 MADE_1000270 09de6254121640785b517234e6668121 51 Pfam PF00471 Ribosomal protein L33 4 49 3.8E-18 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1000270 09de6254121640785b517234e6668121 51 Gene3D G3DSA:2.20.28.120 1 51 8.9E-29 T 13-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1000270 09de6254121640785b517234e6668121 51 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 13-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1000270 09de6254121640785b517234e6668121 51 SUPERFAMILY SSF57829 1 49 2.2E-19 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MADE_1000270 09de6254121640785b517234e6668121 51 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 14.977 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1000270 09de6254121640785b517234e6668121 51 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 51 1.1E-23 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 935 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Gene3D G3DSA:3.40.50.11610 727 933 1.2E-171 T 13-10-2018 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 PIRSF PIRSF000157 1 938 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Gene3D G3DSA:3.40.50.12470 560 806 1.2E-171 T 13-10-2018 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Gene3D G3DSA:3.40.50.970 172 537 3.8E-146 T 13-10-2018 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Gene3D G3DSA:1.10.287.1150 90 171 1.1E-26 T 13-10-2018 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 794 936 2.0E-53 T 13-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 SUPERFAMILY SSF52518 580 797 8.05E-52 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Pfam PF00676 Dehydrogenase E1 component 220 521 7.5E-52 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Pfam PF02779 Transketolase, pyrimidine binding domain 596 791 3.4E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 50 6.1E-18 T 13-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 SUPERFAMILY SSF52518 125 550 3.47E-86 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1009495 d1fcb8682e8d8d79548cc2b851af4987 939 SMART SM00861 597 790 4.8E-61 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1019130 ddad1d8a615a88ef72f9d3d1650d4746 257 Gene3D G3DSA:3.40.50.80 118 255 2.0E-39 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1019130 ddad1d8a615a88ef72f9d3d1650d4746 257 Pfam PF08021 Siderophore-interacting FAD-binding domain 11 117 4.3E-25 T 13-10-2018 IPR013113 FAD-binding 9, siderophore-interacting MADE_1019130 ddad1d8a615a88ef72f9d3d1650d4746 257 SUPERFAMILY SSF63380 4 116 1.33E-13 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_1019130 ddad1d8a615a88ef72f9d3d1650d4746 257 Pfam PF04954 Siderophore-interacting protein 125 235 5.2E-28 T 13-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain MADE_1019130 ddad1d8a615a88ef72f9d3d1650d4746 257 Gene3D G3DSA:2.40.30.10 1 117 5.2E-30 T 13-10-2018 MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 Pfam PF01769 Divalent cation transporter 326 444 5.4E-23 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 Gene3D G3DSA:1.25.60.10 8 134 8.2E-19 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 Gene3D G3DSA:3.10.580.10 135 262 4.8E-38 T 13-10-2018 MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 SMART SM00924 36 139 1.3E-33 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 TIGRFAM TIGR00400 mgtE: magnesium transporter 17 451 1.1E-93 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 Pfam PF03448 MgtE intracellular N domain 36 137 1.9E-23 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 Gene3D G3DSA:1.10.357.20 277 452 9.4E-46 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 SMART SM00116 210 258 0.028 T 13-10-2018 IPR000644 CBS domain MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 SMART SM00116 146 199 15.0 T 13-10-2018 IPR000644 CBS domain MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 SUPERFAMILY SSF158791 11 136 1.26E-28 T 13-10-2018 MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 SUPERFAMILY SSF54631 138 278 4.8E-31 T 13-10-2018 MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 SUPERFAMILY SSF161093 280 451 6.8E-45 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 Pfam PF00571 CBS domain 203 257 3.3E-6 T 13-10-2018 IPR000644 CBS domain MADE_1004160 c85527fde166d53815cc3236b39e2d4f 452 Pfam PF00571 CBS domain 142 197 1.9E-4 T 13-10-2018 IPR000644 CBS domain MADE_1003065 60fb8e384c3d64186df5eb03a6ea6f26 92 Gene3D G3DSA:3.30.2310.20 1 92 2.6E-39 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1003065 60fb8e384c3d64186df5eb03a6ea6f26 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 3 92 1.6E-28 T 13-10-2018 IPR007711 Toxin HigB-1 MADE_1003065 60fb8e384c3d64186df5eb03a6ea6f26 92 SUPERFAMILY SSF143011 1 92 1.44E-16 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1012195 b1b5eb473e68f3697681b316165cbe0c 354 SUPERFAMILY SSF53955 52 353 1.44E-91 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1012195 b1b5eb473e68f3697681b316165cbe0c 354 Gene3D G3DSA:1.10.8.350 70 232 1.3E-83 T 13-10-2018 MADE_1012195 b1b5eb473e68f3697681b316165cbe0c 354 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 57 351 4.4E-108 T 13-10-2018 IPR011970 Lytic murein transglycosylase MADE_1012195 b1b5eb473e68f3697681b316165cbe0c 354 Gene3D G3DSA:1.10.530.10 99 347 1.3E-83 T 13-10-2018 MADE_1012195 b1b5eb473e68f3697681b316165cbe0c 354 Pfam PF13406 Transglycosylase SLT domain 57 348 1.5E-101 T 13-10-2018 IPR031304 Transglycosylase SLT domain 2 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 SUPERFAMILY SSF52540 3 301 1.86E-86 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 6.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 6.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 6.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 6.0E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 Pfam PF01926 50S ribosome-binding GTPase 5 115 2.5E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 45.829 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 Gene3D G3DSA:3.40.50.300 4 278 2.7E-152 T 13-10-2018 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 9.4E-168 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 7.0E-40 T 13-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 Gene3D G3DSA:1.10.150.300 113 200 2.7E-152 T 13-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 PIRSF PIRSF006641 1 363 1.1E-157 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 SUPERFAMILY SSF81271 279 360 1.02E-36 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 MADE_1007555 911389b3eae909bb26f4cb30989a6699 363 Gene3D G3DSA:3.10.20.30 48 361 2.7E-152 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1012970 5df1d5af922afdf9aa98e94d3a7dcf80 348 Gene3D G3DSA:2.40.10.240 64 161 1.6E-121 T 13-10-2018 MADE_1012970 5df1d5af922afdf9aa98e94d3a7dcf80 348 Pfam PF02547 Queuosine biosynthesis protein 3 345 2.0E-135 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MADE_1012970 5df1d5af922afdf9aa98e94d3a7dcf80 348 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 345 1.9E-151 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MADE_1012970 5df1d5af922afdf9aa98e94d3a7dcf80 348 Gene3D G3DSA:3.40.1780.10 14 345 1.6E-121 T 13-10-2018 MADE_1012970 5df1d5af922afdf9aa98e94d3a7dcf80 348 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 346 47.268 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MADE_1012970 5df1d5af922afdf9aa98e94d3a7dcf80 348 SUPERFAMILY SSF111337 1 345 8.11E-137 T 13-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 MADE_1016310 1d61c1e9666258fb2651445d0f56554b 185 Pfam PF07273 Protein of unknown function (DUF1439) 27 178 8.5E-36 T 13-10-2018 IPR010835 Protein of unknown function DUF1439 MADE_1016310 1d61c1e9666258fb2651445d0f56554b 185 Gene3D G3DSA:3.15.10.40 13 182 6.4E-38 T 13-10-2018 MADE_1003975 6142621a7b7ca30bf5c62b0e40bea632 124 Gene3D G3DSA:2.60.40.1470 1 124 1.1E-44 T 13-10-2018 IPR036767 ApaG domain superfamily MADE_1003975 6142621a7b7ca30bf5c62b0e40bea632 124 Pfam PF04379 ApaG domain 21 101 1.7E-33 T 13-10-2018 IPR007474 ApaG domain MADE_1003975 6142621a7b7ca30bf5c62b0e40bea632 124 SUPERFAMILY SSF110069 5 124 9.94E-45 T 13-10-2018 IPR036767 ApaG domain superfamily MADE_1006400 c2027ea6432aaa6c0e8c111090f3192e 188 Gene3D G3DSA:3.40.50.360 1 188 2.2E-52 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1006400 c2027ea6432aaa6c0e8c111090f3192e 188 SUPERFAMILY SSF52218 3 182 2.1E-49 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1006400 c2027ea6432aaa6c0e8c111090f3192e 188 Pfam PF03358 NADPH-dependent FMN reductase 2 153 8.6E-40 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 468 486 7.8E-18 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 629 645 7.8E-18 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 508 526 7.8E-18 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 385 404 7.8E-18 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 SUPERFAMILY SSF51971 341 527 7.3E-40 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 Gene3D G3DSA:3.20.20.70 10 377 9.7E-130 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 630 644 3.5E-6 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 406 3.5E-6 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 383 651 3.8E-23 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 SUPERFAMILY SSF51395 10 370 1.1E-114 T 13-10-2018 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 14 339 1.8E-89 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 Gene3D G3DSA:3.50.50.60 480 636 5.3E-109 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 SUPERFAMILY SSF51905 478 638 2.2E-20 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1012100 7fe8f8da030e0cc5f498c0ba2a4bb5fa 680 Gene3D G3DSA:3.40.50.720 383 674 5.3E-109 T 13-10-2018 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 Pfam PF01207 Dihydrouridine synthase (Dus) 2 291 9.0E-76 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 SUPERFAMILY SSF51395 4 275 9.99E-62 T 13-10-2018 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 Gene3D G3DSA:1.20.120.1460 222 300 1.7E-21 T 13-10-2018 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 1 295 7.5E-124 T 13-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 Gene3D G3DSA:3.20.20.70 1 218 7.6E-65 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 296 41.877 T 13-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 PIRSF PIRSF006621 1 281 3.5E-64 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_1016775 69e4f881ccab0bde705cbb1ab8eb43e6 309 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 61 79 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PIRSF PIRSF500210 2 325 3.2E-118 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 263 275 - T 13-10-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 2 323 44.816 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 169 192 3.2E-61 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 195 222 3.2E-61 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 297 322 3.2E-61 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 59 85 3.2E-61 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 138 161 3.2E-61 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 22 49 3.2E-61 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 184 9.0E-53 T 13-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 Gene3D G3DSA:3.30.540.10 3 185 3.6E-60 T 13-10-2018 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 SUPERFAMILY SSF56655 3 320 1.55E-109 T 13-10-2018 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 Gene3D G3DSA:3.40.190.80 186 320 4.4E-52 T 13-10-2018 MADE_1001055 0ed761f17f937fb5ba56d7f7501b7ea7 325 PIRSF PIRSF000904 2 325 6.6E-115 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 SUPERFAMILY SSF46955 4 129 8.06E-30 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 8.7E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 8.7E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 8.7E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 Pfam PF13411 MerR HTH family regulatory protein 4 70 3.7E-20 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 4 129 1.7E-52 T 13-10-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 Gene3D G3DSA:1.10.1660.10 2 128 1.1E-32 T 13-10-2018 MADE_1005585 33e477bc9a7443651b1c2b9478859979 131 SMART SM00422 4 72 4.1E-23 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1020320 ed44ec9a1ac056e93939af1a1a875d46 796 SUPERFAMILY SSF52540 526 773 6.18E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020320 ed44ec9a1ac056e93939af1a1a875d46 796 SMART SM00487 418 594 9.5E-25 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1020320 ed44ec9a1ac056e93939af1a1a875d46 796 Gene3D G3DSA:3.40.50.300 412 589 7.7E-40 T 13-10-2018 MADE_1020320 ed44ec9a1ac056e93939af1a1a875d46 796 Pfam PF04851 Type III restriction enzyme, res subunit 420 564 1.9E-20 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MADE_1020320 ed44ec9a1ac056e93939af1a1a875d46 796 Gene3D G3DSA:3.40.50.300 604 792 2.2E-34 T 13-10-2018 MADE_1020320 ed44ec9a1ac056e93939af1a1a875d46 796 SUPERFAMILY SSF52540 325 581 1.9E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019100 82bea98d30b82d5bb6066f7a728e18ae 256 Pfam PF01925 Sulfite exporter TauE/SafE 23 247 4.3E-17 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MADE_1008200 00b83a086bb6d153aecf3bcaf3d77499 248 Pfam PF03567 Sulfotransferase family 6 92 4.6E-13 T 13-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 MADE_1009310 c2196552a1f832dd8079894b6a27693c 134 Pfam PF01124 MAPEG family 5 128 1.1E-14 T 13-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein MADE_1009310 c2196552a1f832dd8079894b6a27693c 134 Gene3D G3DSA:1.20.120.550 3 132 6.7E-9 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MADE_1009310 c2196552a1f832dd8079894b6a27693c 134 SUPERFAMILY SSF161084 6 125 2.16E-18 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MADE_1008800 ae8aebf62a1baf35b0e3c2d3711e2be8 349 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 67 266 3.1E-33 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1008800 ae8aebf62a1baf35b0e3c2d3711e2be8 349 Gene3D G3DSA:2.40.50.100 66 194 2.4E-75 T 13-10-2018 MADE_1008800 ae8aebf62a1baf35b0e3c2d3711e2be8 349 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 42 346 1.2E-81 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1008800 ae8aebf62a1baf35b0e3c2d3711e2be8 349 SUPERFAMILY SSF111369 55 272 2.62E-44 T 13-10-2018 MADE_1008800 ae8aebf62a1baf35b0e3c2d3711e2be8 349 Gene3D G3DSA:2.40.420.20 277 344 2.4E-75 T 13-10-2018 MADE_1008800 ae8aebf62a1baf35b0e3c2d3711e2be8 349 Gene3D G3DSA:1.10.287.470 101 160 2.4E-75 T 13-10-2018 MADE_1008800 ae8aebf62a1baf35b0e3c2d3711e2be8 349 Gene3D G3DSA:2.40.30.170 53 276 2.4E-75 T 13-10-2018 MADE_1010320 5563877fffc1c7a4b4930787ed0a803b 237 SUPERFAMILY SSF54001 20 146 1.39E-17 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MADE_1010320 5563877fffc1c7a4b4930787ed0a803b 237 Pfam PF01841 Transglutaminase-like superfamily 35 136 1.4E-12 T 13-10-2018 IPR002931 Transglutaminase-like MADE_1010320 5563877fffc1c7a4b4930787ed0a803b 237 Gene3D G3DSA:3.10.620.30 3 147 2.4E-12 T 13-10-2018 MADE_1006850 3d4a8122190020588a7f3bea9f88824a 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 3.3E-6 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1006850 3d4a8122190020588a7f3bea9f88824a 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 3.3E-6 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1006850 3d4a8122190020588a7f3bea9f88824a 443 Gene3D G3DSA:1.10.287.130 195 292 2.7E-5 T 13-10-2018 MADE_1006850 3d4a8122190020588a7f3bea9f88824a 443 SMART SM00387 337 443 2.9E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1006850 3d4a8122190020588a7f3bea9f88824a 443 Gene3D G3DSA:3.30.565.10 298 442 5.9E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1006850 3d4a8122190020588a7f3bea9f88824a 443 SUPERFAMILY SSF55874 302 440 4.98E-27 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1006850 3d4a8122190020588a7f3bea9f88824a 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 440 6.4E-13 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001022095 031cef9df3f3f87f4817a2e3ef458106 252 Gene3D G3DSA:2.50.20.10 57 252 1.0E-37 T 13-10-2018 MADE_000001022095 031cef9df3f3f87f4817a2e3ef458106 252 SUPERFAMILY SSF89392 60 252 3.88E-40 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MADE_000001022095 031cef9df3f3f87f4817a2e3ef458106 252 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 56 252 1.7E-26 T 13-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MADE_000001022095 031cef9df3f3f87f4817a2e3ef458106 252 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 36 251 23.593 T 13-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 MADE_000001022095 031cef9df3f3f87f4817a2e3ef458106 252 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 68 240 8.8E-38 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 SUPERFAMILY SSF51395 3 334 1.58E-102 T 13-10-2018 MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 79 98 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 Gene3D G3DSA:3.20.20.70 1 335 3.9E-136 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 Pfam PF01180 Dihydroorotate dehydrogenase 46 334 3.2E-93 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 291 311 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 335 48.636 T 13-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 PIRSF PIRSF000164 15 335 1.9E-100 T 13-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 MADE_1010170 76c7bf3b1934fc53798c971ad8d1099d 335 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 334 3.2E-136 T 13-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 MADE_1007950 890cec6de4b29c74e7f7e4bff1d93502 303 Pfam PF01522 Polysaccharide deacetylase 76 164 5.2E-15 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MADE_1007950 890cec6de4b29c74e7f7e4bff1d93502 303 Gene3D G3DSA:3.20.20.370 1 303 2.0E-105 T 13-10-2018 MADE_1007950 890cec6de4b29c74e7f7e4bff1d93502 303 SUPERFAMILY SSF88713 6 300 1.92E-93 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MADE_1007950 890cec6de4b29c74e7f7e4bff1d93502 303 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 6 300 1.8E-158 T 13-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 MADE_000001022520 eb75a009d920eb7520d3c5b9bc737bb9 64 Gene3D G3DSA:3.30.70.1680 13 63 2.4E-5 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 MADE_000001022520 eb75a009d920eb7520d3c5b9bc737bb9 64 Pfam PF02599 Global regulator protein family 24 57 2.4E-5 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MADE_1002010 a154ae9578cd2e6f954ba90823a456ee 102 SUPERFAMILY SSF50341 15 99 1.07E-23 T 13-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 MADE_1002010 a154ae9578cd2e6f954ba90823a456ee 102 SMART SM00260 13 100 4.9E-5 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1002010 a154ae9578cd2e6f954ba90823a456ee 102 Pfam PF01584 CheW-like domain 17 99 3.2E-22 T 13-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 MADE_1002010 a154ae9578cd2e6f954ba90823a456ee 102 Gene3D G3DSA:2.40.50.180 36 99 2.3E-24 T 13-10-2018 MADE_1002010 a154ae9578cd2e6f954ba90823a456ee 102 Gene3D G3DSA:2.30.30.40 20 35 2.3E-24 T 13-10-2018 MADE_1017375 39764852154550277c1c0e6e5a35c0fe 525 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 139 318 1.4E-32 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1017375 39764852154550277c1c0e6e5a35c0fe 525 SMART SM00283 91 352 2.8E-37 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1017375 39764852154550277c1c0e6e5a35c0fe 525 SUPERFAMILY SSF58104 97 353 3.66E-53 T 13-10-2018 MADE_1017375 39764852154550277c1c0e6e5a35c0fe 525 Gene3D G3DSA:1.10.287.950 64 367 1.6E-50 T 13-10-2018 MADE_1017375 39764852154550277c1c0e6e5a35c0fe 525 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 218 247 1.3E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1017375 39764852154550277c1c0e6e5a35c0fe 525 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 112 141 1.3E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1017375 39764852154550277c1c0e6e5a35c0fe 525 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 189 216 1.3E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1003715 c85e6f22fa78e3d2021a15193ed3f27b 331 Gene3D G3DSA:1.20.970.10 4 73 2.7E-21 T 13-10-2018 MADE_1003715 c85e6f22fa78e3d2021a15193ed3f27b 331 Gene3D G3DSA:3.40.1030.10 74 325 1.0E-46 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1003715 c85e6f22fa78e3d2021a15193ed3f27b 331 SUPERFAMILY SSF47648 10 73 1.7E-15 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1003715 c85e6f22fa78e3d2021a15193ed3f27b 331 SUPERFAMILY SSF52418 80 322 3.92E-45 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1003715 c85e6f22fa78e3d2021a15193ed3f27b 331 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 70 5.2E-15 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1003715 c85e6f22fa78e3d2021a15193ed3f27b 331 Pfam PF00591 Glycosyl transferase family, a/b domain 142 253 1.1E-4 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 MADE_1010700 11e353c134645720e3567c5c5bba6acd 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 10 120 1.2E-23 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MADE_1010700 11e353c134645720e3567c5c5bba6acd 127 TIGRFAM TIGR00494 crcB: protein CrcB 11 123 7.9E-29 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MADE_1010700 11e353c134645720e3567c5c5bba6acd 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 8 126 18.167 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 MADE_1008175 3273f34ad67cfd3d3fef33c02bae90cb 365 Pfam PF00534 Glycosyl transferases group 1 199 331 1.5E-24 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1008175 3273f34ad67cfd3d3fef33c02bae90cb 365 Gene3D G3DSA:3.40.50.2000 187 324 3.4E-29 T 13-10-2018 MADE_1008175 3273f34ad67cfd3d3fef33c02bae90cb 365 SUPERFAMILY SSF53756 1 357 8.07E-60 T 13-10-2018 MADE_1008175 3273f34ad67cfd3d3fef33c02bae90cb 365 Pfam PF13439 Glycosyltransferase Family 4 15 175 3.8E-18 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1008175 3273f34ad67cfd3d3fef33c02bae90cb 365 Gene3D G3DSA:3.40.50.2000 1 183 3.7E-25 T 13-10-2018 MADE_000001021030 28fa08a0b8c07dc3e17ed41c6544a922 352 Gene3D G3DSA:2.40.420.20 274 341 1.4E-62 T 13-10-2018 MADE_000001021030 28fa08a0b8c07dc3e17ed41c6544a922 352 Gene3D G3DSA:2.40.30.170 51 273 1.4E-62 T 13-10-2018 MADE_000001021030 28fa08a0b8c07dc3e17ed41c6544a922 352 Gene3D G3DSA:1.10.287.470 98 157 1.4E-62 T 13-10-2018 MADE_000001021030 28fa08a0b8c07dc3e17ed41c6544a922 352 Gene3D G3DSA:2.40.50.100 63 191 1.4E-62 T 13-10-2018 MADE_000001021030 28fa08a0b8c07dc3e17ed41c6544a922 352 SUPERFAMILY SSF111369 51 268 3.14E-36 T 13-10-2018 MADE_000001021030 28fa08a0b8c07dc3e17ed41c6544a922 352 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 52 342 5.9E-61 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_000001021030 28fa08a0b8c07dc3e17ed41c6544a922 352 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 67 262 5.2E-16 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1008385 59047a6e37ca864bcecf82bb8fb030ba 271 Pfam PF13622 Thioesterase-like superfamily 28 268 9.4E-46 T 13-10-2018 MADE_1008385 59047a6e37ca864bcecf82bb8fb030ba 271 Gene3D G3DSA:3.10.129.90 11 270 5.3E-69 T 13-10-2018 MADE_1008385 59047a6e37ca864bcecf82bb8fb030ba 271 SUPERFAMILY SSF54637 133 269 2.75E-23 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1008385 59047a6e37ca864bcecf82bb8fb030ba 271 SUPERFAMILY SSF54637 2 116 5.86E-24 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1018455 6da529db584a648ace8fed69b93570e6 243 Gene3D G3DSA:3.20.20.450 3 242 2.9E-45 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1018455 6da529db584a648ace8fed69b93570e6 243 Pfam PF00563 EAL domain 4 232 1.2E-42 T 13-10-2018 IPR001633 EAL domain MADE_1018455 6da529db584a648ace8fed69b93570e6 243 SUPERFAMILY SSF141868 10 233 6.54E-44 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1018455 6da529db584a648ace8fed69b93570e6 243 SMART SM00052 3 237 7.8E-11 T 13-10-2018 IPR001633 EAL domain MADE_1018525 736c67d64ab76ced0c2b0edae0d40439 346 Pfam PF07859 alpha/beta hydrolase fold 121 320 9.0E-40 T 13-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 MADE_1018525 736c67d64ab76ced0c2b0edae0d40439 346 SUPERFAMILY SSF53474 105 342 8.71E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1018525 736c67d64ab76ced0c2b0edae0d40439 346 Gene3D G3DSA:3.40.50.1820 31 343 4.6E-77 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 Gene3D G3DSA:3.50.50.60 12 372 2.4E-137 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 Pfam PF01266 FAD dependent oxidoreductase 12 330 6.0E-52 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 16 33 - T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 Gene3D G3DSA:1.10.8.870 397 466 3.7E-23 T 13-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 SUPERFAMILY SSF51905 10 377 3.08E-35 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 SUPERFAMILY SSF54373 232 325 8.63E-8 T 13-10-2018 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 358 368 - T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 387 491 1.0E-10 T 13-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 11 23 7.9E-28 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 24 34 7.9E-28 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 319 325 7.9E-28 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 40 52 7.9E-28 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 85 97 7.9E-28 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 353 365 7.9E-28 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 MADE_1001195 41ffea3fa755620b782af8baa1cfec71 512 Gene3D G3DSA:3.30.9.10 89 326 2.4E-137 T 13-10-2018 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 Pfam PF13411 MerR HTH family regulatory protein 25 90 7.4E-17 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 SMART SM00422 25 93 8.7E-19 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 49 2.8E-16 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 25 36 2.8E-16 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 60 80 2.8E-16 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 ProSitePatterns PS00552 MerR-type HTH domain signature. 27 49 - T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 Gene3D G3DSA:1.10.1660.10 16 146 9.8E-30 T 13-10-2018 MADE_1005525 d684688333f361bc234e01e4854f97a6 150 SUPERFAMILY SSF46955 25 147 1.03E-27 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1005525 d684688333f361bc234e01e4854f97a6 150 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 25 147 2.9E-57 T 13-10-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 MADE_1016085 ec55a2af158bfe03b7fcb37f21a38b7e 177 SUPERFAMILY SSF88659 119 175 6.35E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1016085 ec55a2af158bfe03b7fcb37f21a38b7e 177 Gene3D G3DSA:1.10.1740.10 8 88 1.3E-26 T 13-10-2018 MADE_1016085 ec55a2af158bfe03b7fcb37f21a38b7e 177 Pfam PF08281 Sigma-70, region 4 120 171 7.4E-9 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1016085 ec55a2af158bfe03b7fcb37f21a38b7e 177 Gene3D G3DSA:1.10.10.10 89 177 1.7E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016085 ec55a2af158bfe03b7fcb37f21a38b7e 177 Pfam PF04542 Sigma-70 region 2 24 90 4.5E-13 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1016085 ec55a2af158bfe03b7fcb37f21a38b7e 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 175 5.3E-23 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1016085 ec55a2af158bfe03b7fcb37f21a38b7e 177 SUPERFAMILY SSF88946 2 103 3.14E-22 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1018390 10460df46542758043e341e71683f553 223 Gene3D G3DSA:3.40.50.150 28 223 3.2E-56 T 13-10-2018 MADE_1018390 10460df46542758043e341e71683f553 223 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 36 221 5.6E-57 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MADE_1018390 10460df46542758043e341e71683f553 223 SUPERFAMILY SSF53335 41 217 1.02E-47 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1018390 10460df46542758043e341e71683f553 223 PIRSF PIRSF004553 40 223 5.5E-50 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 MADE_1018390 10460df46542758043e341e71683f553 223 Pfam PF03602 Conserved hypothetical protein 95 41 219 2.6E-54 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:1.20.1640.10 18 503 4.6E-253 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:3.30.70.1430 561 660 4.6E-253 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:3.30.70.1440 661 858 4.6E-253 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 SUPERFAMILY SSF82714 721 795 2.49E-8 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Pfam PF00873 AcrB/AcrD/AcrF family 12 1018 1.4E-157 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 SUPERFAMILY SSF82866 295 490 1.57E-37 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:3.30.2090.10 182 272 4.6E-253 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 SUPERFAMILY SSF82693 48 139 1.65E-15 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 SUPERFAMILY SSF82714 187 269 2.09E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:3.30.70.1320 141 329 4.6E-253 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 PRINTS PR00702 Acriflavin resistance protein family signature 18 42 1.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 PRINTS PR00702 Acriflavin resistance protein family signature 46 64 1.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 1.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 1.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 1.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 1.9E-26 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:1.20.1640.10 504 1015 4.6E-253 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:3.30.2090.10 710 797 4.6E-253 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 Gene3D G3DSA:3.30.70.1430 48 805 4.6E-253 T 13-10-2018 MADE_000001021340 52a1c6a3ff128aee27fce7f625f70798 1056 SUPERFAMILY SSF82866 794 1020 8.5E-47 T 13-10-2018 MADE_000001023370 5f0891fb1661bab2514378a647f32e3a 132 Pfam PF13840 ACT domain 73 128 1.0E-12 T 13-10-2018 IPR027795 CASTOR, ACT domain MADE_000001023370 5f0891fb1661bab2514378a647f32e3a 132 Pfam PF10000 ACT domain 3 70 4.3E-17 T 13-10-2018 IPR018717 Domain of unknown function DUF2241 MADE_000001023370 5f0891fb1661bab2514378a647f32e3a 132 Gene3D G3DSA:3.30.2130.10 1 132 1.9E-39 T 13-10-2018 MADE_000001023370 5f0891fb1661bab2514378a647f32e3a 132 SUPERFAMILY SSF55021 3 68 3.39E-13 T 13-10-2018 MADE_000001023370 5f0891fb1661bab2514378a647f32e3a 132 SUPERFAMILY SSF55021 70 131 1.08E-19 T 13-10-2018 MADE_1008310 8de364a6250f8d2b048ebd7b89704bab 171 SUPERFAMILY SSF89028 1 169 9.22E-54 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MADE_1008310 8de364a6250f8d2b048ebd7b89704bab 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 168 2.3E-52 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MADE_1008310 8de364a6250f8d2b048ebd7b89704bab 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 169 2.0E-30 T 13-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MADE_1008310 8de364a6250f8d2b048ebd7b89704bab 171 Gene3D G3DSA:1.20.1200.10 17 171 7.0E-52 T 13-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MADE_1008310 8de364a6250f8d2b048ebd7b89704bab 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 1.6E-53 T 13-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 Gene3D G3DSA:3.20.20.450 433 683 1.0E-86 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 Pfam PF00563 EAL domain 440 670 4.1E-71 T 13-10-2018 IPR001633 EAL domain MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 Gene3D G3DSA:3.30.70.270 251 426 1.9E-48 T 13-10-2018 MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 Pfam PF00990 Diguanylate cyclase, GGDEF domain 266 419 1.1E-39 T 13-10-2018 IPR000160 GGDEF domain MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 SUPERFAMILY SSF141868 440 682 2.88E-79 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 263 421 2.4E-37 T 13-10-2018 IPR000160 GGDEF domain MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 SMART SM00052 434 675 3.7E-85 T 13-10-2018 IPR001633 EAL domain MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 SMART SM00267 254 424 2.3E-49 T 13-10-2018 IPR000160 GGDEF domain MADE_1007350 a877c85ee060375de4cc4d4927d8d14c 684 SUPERFAMILY SSF55073 270 425 2.35E-41 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 Pfam PF00849 RNA pseudouridylate synthase 71 196 1.4E-14 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 106 120 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 Pfam PF01479 S4 domain 8 52 3.0E-9 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 Gene3D G3DSA:3.10.290.10 2 60 1.7E-20 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 75 228 1.8E-45 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 SUPERFAMILY SSF55120 70 231 4.32E-39 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 Gene3D G3DSA:3.30.70.580 72 230 7.6E-54 T 13-10-2018 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 SMART SM00363 7 68 2.6E-9 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 Gene3D G3DSA:3.30.70.1560 136 209 7.6E-54 T 13-10-2018 MADE_1008945 6abdfeea95f852a2608bf1b9677e3b98 248 SUPERFAMILY SSF55174 8 59 2.02E-12 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 ProSitePatterns PS00756 Protein secY signature 2. 169 186 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 268 287 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 311 333 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 176 199 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 150 175 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PRINTS PR00303 Preprotein translocase SecY subunit signature 366 384 5.4E-98 T 13-10-2018 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 SUPERFAMILY SSF103491 14 420 3.4E-133 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 425 1.1E-136 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 PIRSF PIRSF004557 10 437 2.7E-127 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 Pfam PF00344 SecY translocase 74 413 1.5E-116 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 429 29.599 T 13-10-2018 IPR026593 Protein translocase subunit SecY MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1013960 179c45af88f81c2a66bba4521233c6bf 439 Gene3D G3DSA:1.10.3370.10 11 425 3.2E-160 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 SMART SM00388 392 457 3.3E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 Gene3D G3DSA:3.30.565.10 456 624 6.0E-50 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 Gene3D G3DSA:1.10.287.130 358 455 4.8E-26 T 13-10-2018 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 599 7.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 560 7.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 PRINTS PR00344 Bacterial sensor protein C-terminal signature 605 618 7.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 574 7.3E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 SUPERFAMILY SSF47384 377 458 2.94E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 SMART SM01358 35 278 1.1E-24 T 13-10-2018 IPR032255 Helical bimodular sensor domain MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 504 620 1.9E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 Pfam PF00512 His Kinase A (phospho-acceptor) domain 392 457 8.2E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 Gene3D G3DSA:1.10.8.500 308 357 5.2E-9 T 13-10-2018 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 SMART SM00387 504 621 2.5E-36 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 SMART SM00448 769 882 3.7E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 SUPERFAMILY SSF52172 770 886 1.11E-37 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 SUPERFAMILY SSF55874 446 621 5.89E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 Pfam PF00072 Response regulator receiver domain 771 882 5.8E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016045 5ac68e6a39815c81ae3eb496ce087957 891 Gene3D G3DSA:3.40.50.2300 768 891 4.8E-43 T 13-10-2018 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 Hamap MF_00930 Transcription elongation factor GreB [greB]. 1 156 50.77 T 13-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 3.6E-25 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 7.2E-21 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 PIRSF PIRSF006092 1 157 1.4E-44 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 SUPERFAMILY SSF46557 3 78 6.28E-27 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 Gene3D G3DSA:1.10.287.180 1 76 4.6E-31 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 2 155 3.9E-76 T 13-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 154 26.987 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 Gene3D G3DSA:3.10.50.30 77 158 4.0E-29 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 119 135 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 MADE_1019985 131d6f9fb03579784a20617580f7b25f 161 SUPERFAMILY SSF54534 80 155 6.02E-19 T 13-10-2018 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 37.963 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 SUPERFAMILY SSF53223 3 122 7.29E-40 T 13-10-2018 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 280 3.5E-69 T 13-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 Gene3D G3DSA:3.40.50.10860 8 276 2.5E-109 T 13-10-2018 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 2.2E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 2.2E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 2.2E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 2.2E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 2.2E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 2.2E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 2.2E-84 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 Gene3D G3DSA:3.40.50.720 6 259 2.5E-109 T 13-10-2018 MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 SUPERFAMILY SSF51735 123 281 2.76E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1005310 b8bc95fe79315d288f8cafd23ce20fdc 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 1.1E-39 T 13-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 MADE_1008215 717a5489e163096d2a17bb32bbb521dc 365 Pfam PF00534 Glycosyl transferases group 1 198 337 3.4E-24 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1008215 717a5489e163096d2a17bb32bbb521dc 365 SUPERFAMILY SSF53756 8 365 7.42E-52 T 13-10-2018 MADE_1008215 717a5489e163096d2a17bb32bbb521dc 365 Gene3D G3DSA:3.40.50.2000 96 360 1.4E-43 T 13-10-2018 MADE_1008215 717a5489e163096d2a17bb32bbb521dc 365 Gene3D G3DSA:3.40.50.2000 181 349 1.4E-43 T 13-10-2018 MADE_1008215 717a5489e163096d2a17bb32bbb521dc 365 Pfam PF13439 Glycosyltransferase Family 4 18 184 1.5E-6 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1006700 55cbed80a6147aa5f0c67bfabbfee707 260 Pfam PF02582 Uncharacterised ACR, YagE family COG1723 44 209 1.9E-45 T 13-10-2018 IPR003734 Domain of unknown function DUF155 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 Gene3D G3DSA:3.30.300.10 11 270 6.3E-178 T 13-10-2018 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 8.2E-45 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 SUPERFAMILY SSF55973 233 378 3.92E-70 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 Gene3D G3DSA:3.30.300.10 103 372 6.3E-178 T 13-10-2018 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 Gene3D G3DSA:3.30.300.10 5 233 6.3E-178 T 13-10-2018 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 381 58.755 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 SUPERFAMILY SSF55973 111 232 1.35E-52 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 379 1.4E-195 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 SUPERFAMILY SSF55973 4 109 8.63E-48 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 PIRSF PIRSF000497 1 381 1.9E-173 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 369 5.1E-69 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004340 0d6e83e1346c645557c7e5480bb59e85 381 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 4.0E-43 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 MADE_1004805 dee61b53245d0bb5581d6e1449caef92 304 PRINTS PR01805 VacJ lipoprotein signature 65 81 6.4E-23 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MADE_1004805 dee61b53245d0bb5581d6e1449caef92 304 PRINTS PR01805 VacJ lipoprotein signature 152 169 6.4E-23 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MADE_1004805 dee61b53245d0bb5581d6e1449caef92 304 PRINTS PR01805 VacJ lipoprotein signature 47 60 6.4E-23 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MADE_1004805 dee61b53245d0bb5581d6e1449caef92 304 PRINTS PR01805 VacJ lipoprotein signature 116 133 6.4E-23 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MADE_1004805 dee61b53245d0bb5581d6e1449caef92 304 Pfam PF04333 MlaA lipoprotein 46 236 2.8E-67 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 MADE_1001700 6e767e6283594a1576459cf977fd75f3 377 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 7 358 8.0E-103 T 13-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MADE_1001700 6e767e6283594a1576459cf977fd75f3 377 Gene3D G3DSA:3.40.50.11750 14 250 2.9E-95 T 13-10-2018 MADE_1001700 6e767e6283594a1576459cf977fd75f3 377 PIRSF PIRSF005622 1 363 1.2E-111 T 13-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MADE_1001700 6e767e6283594a1576459cf977fd75f3 377 Pfam PF01924 Hydrogenase formation hypA family 4 356 1.6E-114 T 13-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 MADE_1001700 6e767e6283594a1576459cf977fd75f3 377 Gene3D G3DSA:3.40.50.11740 51 290 2.9E-95 T 13-10-2018 MADE_1001700 6e767e6283594a1576459cf977fd75f3 377 Gene3D G3DSA:1.10.10.2140 309 359 4.2E-19 T 13-10-2018 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 TIGRFAM TIGR01799 CM_T: chorismate mutase 11 92 5.6E-33 T 13-10-2018 IPR011277 Chorismate mutase, T-protein GO:0004106|GO:0005737|GO:0006571|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 Pfam PF01817 Chorismate mutase type II 15 92 1.6E-19 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 SUPERFAMILY SSF48600 7 94 2.38E-23 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 Gene3D G3DSA:3.40.50.720 87 253 1.4E-38 T 13-10-2018 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 Pfam PF02153 Prephenate dehydrogenase 144 350 6.0E-29 T 13-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 PIRSF PIRSF001499 7 380 1.7E-142 T 13-10-2018 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 SMART SM00830 15 95 1.6E-30 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 SUPERFAMILY SSF51735 96 244 5.51E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 SUPERFAMILY SSF48179 248 372 4.65E-39 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 Gene3D G3DSA:1.20.59.10 2 86 2.2E-17 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_000001021085 9c59ca34ed83d919460c6c3716ee4340 384 Gene3D G3DSA:1.10.3660.10 255 380 3.7E-44 T 13-10-2018 MADE_000001023125 e91fa12240835b7756642906105302ef 323 Gene3D G3DSA:3.40.190.10 128 224 7.0E-6 T 13-10-2018 MADE_000001023125 e91fa12240835b7756642906105302ef 323 Gene3D G3DSA:3.40.190.10 85 258 7.0E-6 T 13-10-2018 MADE_000001023125 e91fa12240835b7756642906105302ef 323 SUPERFAMILY SSF53850 88 258 1.93E-10 T 13-10-2018 MADE_1009235 ef8f0cde77f499da8fb6b8129dbc32b8 200 SUPERFAMILY SSF53335 10 197 2.84E-28 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1009235 ef8f0cde77f499da8fb6b8129dbc32b8 200 Pfam PF13489 Methyltransferase domain 32 140 1.3E-13 T 13-10-2018 MADE_1009235 ef8f0cde77f499da8fb6b8129dbc32b8 200 Gene3D G3DSA:3.40.50.150 4 151 2.7E-25 T 13-10-2018 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 6 300 34.14 T 13-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 202 299 1.4E-27 T 13-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 Gene3D G3DSA:3.40.190.10 7 221 4.4E-69 T 13-10-2018 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 Gene3D G3DSA:3.40.190.10 102 191 4.4E-69 T 13-10-2018 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 Gene3D G3DSA:3.30.70.120 227 299 2.9E-32 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 Pfam PF08029 HisG, C-terminal domain 224 297 3.0E-23 T 13-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 SUPERFAMILY SSF54913 227 299 2.89E-21 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 156 177 - T 13-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 SUPERFAMILY SSF53850 6 224 7.14E-66 T 13-10-2018 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 Pfam PF01634 ATP phosphoribosyltransferase 54 215 1.2E-45 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MADE_1012295 015364253b2879e9ff7cd8e5b088104a 300 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 7 196 9.0E-55 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 SUPERFAMILY SSF82866 291 487 4.84E-35 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:3.30.70.1430 38 802 5.4E-236 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:3.30.70.1430 554 652 5.4E-236 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:3.30.2090.10 704 794 5.4E-236 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Pfam PF00873 AcrB/AcrD/AcrF family 1 1010 5.3E-154 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 SUPERFAMILY SSF82866 795 1011 3.14E-40 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:3.30.70.1440 653 854 5.4E-236 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:3.30.2090.10 177 267 5.4E-236 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 SUPERFAMILY SSF82693 134 322 6.54E-16 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:1.20.1640.10 8 503 5.4E-236 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:3.30.70.1320 134 325 5.4E-236 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.7E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.7E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.7E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.7E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.7E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.7E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 SUPERFAMILY SSF82714 714 787 2.62E-7 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 SUPERFAMILY SSF82714 182 263 2.35E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 SUPERFAMILY SSF82693 38 133 1.64E-20 T 13-10-2018 MADE_1007865 2468f2c302184643cccaaf7a4a2a814f 1015 Gene3D G3DSA:1.20.1640.10 504 1005 5.4E-236 T 13-10-2018 MADE_1001200 9f5c010f73c0e706d26f48b000ad203a 194 Gene3D G3DSA:3.40.50.1240 2 192 4.1E-6 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_1001200 9f5c010f73c0e706d26f48b000ad203a 194 SUPERFAMILY SSF53254 7 170 6.0E-10 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_1010475 b634cbd2865df04706392feca16e0d73 341 SUPERFAMILY SSF52151 1 326 1.26E-48 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MADE_1010475 b634cbd2865df04706392feca16e0d73 341 Gene3D G3DSA:3.40.1090.10 83 229 1.8E-15 T 13-10-2018 MADE_1010475 b634cbd2865df04706392feca16e0d73 341 Gene3D G3DSA:3.40.1090.20 1 67 7.5E-7 T 13-10-2018 MADE_1010475 b634cbd2865df04706392feca16e0d73 341 Pfam PF01734 Patatin-like phospholipase 115 162 4.7E-7 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MADE_1010475 b634cbd2865df04706392feca16e0d73 341 Pfam PF01734 Patatin-like phospholipase 5 51 2.4E-7 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 SMART SM00990 449 535 1.7E-12 T 13-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 SUPERFAMILY SSF53098 540 703 1.59E-54 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 543 704 6.6E-35 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 Gene3D G3DSA:3.30.420.10 538 705 1.6E-49 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 Pfam PF08774 VRR-NUC domain 468 535 2.2E-9 T 13-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 Gene3D G3DSA:3.40.1350.10 459 537 1.5E-6 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 SMART SM00479 542 707 4.3E-44 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1019690 45031a70be41892ac91adf8fd025c1f0 715 Pfam PF00929 Exonuclease 544 698 2.6E-35 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 16 309 4.4E-89 T 13-10-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 Gene3D G3DSA:2.10.70.40 200 252 2.6E-43 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 172 308 3.3E-21 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 Gene3D G3DSA:1.10.530.10 166 305 2.6E-43 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 PRINTS PR01002 Flagellar protein FlgJ signature 292 310 2.7E-28 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 PRINTS PR01002 Flagellar protein FlgJ signature 205 226 2.7E-28 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 PRINTS PR01002 Flagellar protein FlgJ signature 185 203 2.7E-28 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 PRINTS PR01002 Flagellar protein FlgJ signature 227 248 2.7E-28 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 PRINTS PR01002 Flagellar protein FlgJ signature 32 55 2.7E-28 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 PRINTS PR01002 Flagellar protein FlgJ signature 249 270 2.7E-28 T 13-10-2018 MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 Pfam PF10135 Rod binding protein 54 105 2.0E-17 T 13-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal MADE_1005745 e2f8b0a7224421c76000e60f8d0aa35d 316 SMART SM00047 156 312 7.5E-33 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MADE_1005555 338218479c653d98c45c99d4c89bb841 133 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 22 125 29.122 T 13-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MADE_1005555 338218479c653d98c45c99d4c89bb841 133 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 71 122 1.0E-13 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MADE_1005555 338218479c653d98c45c99d4c89bb841 133 Gene3D G3DSA:3.10.20.400 15 112 3.7E-37 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MADE_1005555 338218479c653d98c45c99d4c89bb841 133 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 48 121 1.5E-32 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 MADE_1005555 338218479c653d98c45c99d4c89bb841 133 SUPERFAMILY SSF141734 24 129 1.11E-44 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 445 46.813 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 SUPERFAMILY SSF53738 156 256 6.67E-30 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 SUPERFAMILY SSF53738 258 365 5.1E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 443 8.7E-188 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 3.3E-13 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 3.3E-13 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 3.3E-13 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Gene3D G3DSA:3.40.120.10 174 362 9.4E-62 T 13-10-2018 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Gene3D G3DSA:3.30.310.50 370 447 6.0E-23 T 13-10-2018 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 364 1.4E-30 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 SUPERFAMILY SSF55957 358 447 1.12E-21 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Gene3D G3DSA:3.40.120.10 257 339 9.4E-62 T 13-10-2018 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 442 1.0E-12 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 135 1.6E-42 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Gene3D G3DSA:3.40.120.10 3 154 1.6E-47 T 13-10-2018 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 SUPERFAMILY SSF53738 2 181 6.67E-48 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_000001021895 b37f6366ad2e76fc3a89839379395019 447 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 2.8E-20 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 MADE_1000340 481c8bed2dd6f5e5a3689d61f7c7eed4 189 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 13 175 25.304 T 13-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 MADE_1000340 481c8bed2dd6f5e5a3689d61f7c7eed4 189 SUPERFAMILY SSF64288 19 175 5.81E-43 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MADE_1000340 481c8bed2dd6f5e5a3689d61f7c7eed4 189 Pfam PF04345 Chorismate lyase 13 176 1.2E-34 T 13-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 MADE_1000340 481c8bed2dd6f5e5a3689d61f7c7eed4 189 Gene3D G3DSA:3.40.1410.10 6 175 2.1E-45 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MADE_1009215 0d6cfe4bcdf690a81febd76e1b7029e5 97 Pfam PF06844 Protein of unknown function (DUF1244) 27 92 2.2E-35 T 13-10-2018 IPR023163 SMc04008-like domain MADE_1009215 0d6cfe4bcdf690a81febd76e1b7029e5 97 Gene3D G3DSA:1.10.3340.10 1 97 3.7E-45 T 13-10-2018 IPR036810 SMc04008-like superfamily MADE_1009215 0d6cfe4bcdf690a81febd76e1b7029e5 97 SUPERFAMILY SSF158757 1 77 2.22E-36 T 13-10-2018 IPR036810 SMc04008-like superfamily MADE_1001820 a7d88565b7d5267242a2a5a47e5d4681 292 Gene3D G3DSA:1.20.1510.10 10 200 8.1E-39 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1001820 a7d88565b7d5267242a2a5a47e5d4681 292 Pfam PF01545 Cation efflux family 15 197 1.5E-39 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MADE_1001820 a7d88565b7d5267242a2a5a47e5d4681 292 SUPERFAMILY SSF161111 7 202 6.15E-46 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1001820 a7d88565b7d5267242a2a5a47e5d4681 292 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 279 5.3E-53 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 SMART SM00387 291 400 1.2E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018955 619033251a820cbd8a9b56e836f39477 408 SMART SM00388 173 246 6.8E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 Gene3D G3DSA:3.30.450.40 1 165 7.0E-8 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1018955 619033251a820cbd8a9b56e836f39477 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 399 4.1E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018955 619033251a820cbd8a9b56e836f39477 408 Pfam PF00512 His Kinase A (phospho-acceptor) domain 175 241 6.1E-8 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 Gene3D G3DSA:1.10.287.130 166 244 1.3E-10 T 13-10-2018 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 Gene3D G3DSA:3.30.565.10 256 404 4.4E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018955 619033251a820cbd8a9b56e836f39477 408 SUPERFAMILY SSF47384 162 243 1.55E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 379 3.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 397 3.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 356 3.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 342 3.9E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018955 619033251a820cbd8a9b56e836f39477 408 SUPERFAMILY SSF55874 258 398 9.04E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018955 619033251a820cbd8a9b56e836f39477 408 SUPERFAMILY SSF55781 16 152 5.89E-14 T 13-10-2018 MADE_1020485 eacb26cca391eea2deec878047608828 277 Pfam PF00119 ATP synthase A chain 48 271 2.0E-52 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020485 eacb26cca391eea2deec878047608828 277 Hamap MF_01393 ATP synthase subunit a [atpB]. 11 277 15.514 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020485 eacb26cca391eea2deec878047608828 277 SUPERFAMILY SSF81336 96 271 7.06E-40 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020485 eacb26cca391eea2deec878047608828 277 Gene3D G3DSA:1.20.120.220 95 277 5.6E-54 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020485 eacb26cca391eea2deec878047608828 277 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 41 271 1.1E-40 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020485 eacb26cca391eea2deec878047608828 277 ProSitePatterns PS00449 ATP synthase a subunit signature. 214 223 - T 13-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1013970 79c1b4fea58ab32189db692891c72a2c 59 SUPERFAMILY SSF55129 1 58 4.32E-21 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MADE_1013970 79c1b4fea58ab32189db692891c72a2c 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 13-10-2018 IPR018038 Ribosomal protein L30, conserved site MADE_1013970 79c1b4fea58ab32189db692891c72a2c 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 8.1E-26 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013970 79c1b4fea58ab32189db692891c72a2c 59 Gene3D G3DSA:3.30.1390.20 1 58 1.1E-25 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily MADE_1013970 79c1b4fea58ab32189db692891c72a2c 59 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 3.3E-20 T 13-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain MADE_1013970 79c1b4fea58ab32189db692891c72a2c 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.558 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013970 79c1b4fea58ab32189db692891c72a2c 59 PIRSF PIRSF002211 1 59 1.0E-26 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 7.9E-22 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 Gene3D G3DSA:1.10.720.10 1 47 1.1E-23 T 13-10-2018 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 SUPERFAMILY SSF68912 1 46 3.92E-13 T 13-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 SMART SM00959 5 47 1.8E-19 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 SMART SM00382 170 355 6.4E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 248.817 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 3.7E-218 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 Gene3D G3DSA:3.40.50.300 130 417 7.4E-132 T 13-10-2018 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 Gene3D G3DSA:2.40.50.140 48 117 2.5E-34 T 13-10-2018 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 SMART SM00357 52 118 8.5E-17 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 1.3E-18 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.3E-31 T 13-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 SUPERFAMILY SSF50249 48 125 9.71E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1002860 04f19d71666acf7c2ae998a4dbdf083c 421 SUPERFAMILY SSF52540 90 371 1.13E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014315 2266eef9821f309348fb3179bf27f9d1 556 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 266 553 3.5E-127 T 13-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type MADE_1014315 2266eef9821f309348fb3179bf27f9d1 556 Pfam PF02653 Branched-chain amino acid transport system / permease component 268 539 7.7E-51 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MADE_1001975 fcd29c11f3bc767f817017fffff83f8b 243 SUPERFAMILY SSF52833 4 81 4.11E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1001975 fcd29c11f3bc767f817017fffff83f8b 243 Gene3D G3DSA:3.40.30.10 10 78 1.2E-9 T 13-10-2018 MADE_1009640 95bcde30ce1892b161ec9b8d7913ccea 511 Gene3D G3DSA:3.40.50.2300 1 108 2.1E-13 T 13-10-2018 MADE_1009640 95bcde30ce1892b161ec9b8d7913ccea 511 Pfam PF00072 Response regulator receiver domain 6 97 1.3E-8 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1009640 95bcde30ce1892b161ec9b8d7913ccea 511 SUPERFAMILY SSF48452 143 455 8.39E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1009640 95bcde30ce1892b161ec9b8d7913ccea 511 Gene3D G3DSA:1.25.40.10 109 489 3.6E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1009640 95bcde30ce1892b161ec9b8d7913ccea 511 SUPERFAMILY SSF52172 5 116 6.59E-15 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 SUPERFAMILY SSF54211 1 181 1.42E-44 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 13-10-2018 IPR018336 Ribonuclease PH, conserved site MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 Gene3D G3DSA:3.30.230.70 13 237 1.6E-61 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 1.8E-112 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 SUPERFAMILY SSF55666 153 236 7.33E-24 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 1.1E-23 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 Pfam PF03725 3' exoribonuclease family, domain 2 157 223 1.5E-8 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 MADE_1020280 db4b4f96e4729c5802f9d3ec75a64111 237 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 44.066 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 MADE_1016855 97c3290d71cb3bc7c6a3ffb032df57c5 371 Gene3D G3DSA:1.10.260.40 9 104 2.2E-24 T 13-10-2018 MADE_1016855 97c3290d71cb3bc7c6a3ffb032df57c5 371 SMART SM00530 19 74 3.5E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1016855 97c3290d71cb3bc7c6a3ffb032df57c5 371 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 14 87 5.6E-18 T 13-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 MADE_1016855 97c3290d71cb3bc7c6a3ffb032df57c5 371 Pfam PF01381 Helix-turn-helix 22 74 1.1E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1016855 97c3290d71cb3bc7c6a3ffb032df57c5 371 Pfam PF06114 IrrE N-terminal-like domain 237 324 5.4E-9 T 13-10-2018 IPR010359 IrrE N-terminal-like domain MADE_1016855 97c3290d71cb3bc7c6a3ffb032df57c5 371 SUPERFAMILY SSF47413 15 96 2.03E-20 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1006155 ba43427893262872ef9fee2877d06c79 373 Pfam PF00158 Sigma-54 interaction domain 11 173 3.7E-59 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1006155 ba43427893262872ef9fee2877d06c79 373 SUPERFAMILY SSF46689 310 363 3.15E-7 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1006155 ba43427893262872ef9fee2877d06c79 373 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 224 233 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_1006155 ba43427893262872ef9fee2877d06c79 373 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 10 361 5.8E-166 T 13-10-2018 IPR014317 Transcription activator PspF MADE_1006155 ba43427893262872ef9fee2877d06c79 373 Gene3D G3DSA:1.10.10.60 302 364 2.0E-9 T 13-10-2018 MADE_1006155 ba43427893262872ef9fee2877d06c79 373 SMART SM00382 30 177 5.0E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1006155 ba43427893262872ef9fee2877d06c79 373 Gene3D G3DSA:3.40.50.300 1 181 1.1E-57 T 13-10-2018 MADE_1006155 ba43427893262872ef9fee2877d06c79 373 SUPERFAMILY SSF52540 10 249 7.98E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006155 ba43427893262872ef9fee2877d06c79 373 Pfam PF02954 Bacterial regulatory protein, Fis family 326 361 1.5E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1006155 ba43427893262872ef9fee2877d06c79 373 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 96 111 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_1006155 ba43427893262872ef9fee2877d06c79 373 Gene3D G3DSA:1.10.8.60 182 265 8.7E-26 T 13-10-2018 MADE_1013600 1fe92caf3807c8f6f9d0af9edefe3128 946 SUPERFAMILY SSF56935 28 945 4.21E-93 T 13-10-2018 MADE_1013600 1fe92caf3807c8f6f9d0af9edefe3128 946 Gene3D G3DSA:2.170.130.10 31 168 1.5E-35 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1013600 1fe92caf3807c8f6f9d0af9edefe3128 946 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 164 1.7E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1013600 1fe92caf3807c8f6f9d0af9edefe3128 946 Pfam PF00593 TonB dependent receptor 407 945 1.1E-42 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1009350 a53a3b7835e637b2feaa0d22e347a8e9 300 SMART SM00028 241 274 31.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1009350 a53a3b7835e637b2feaa0d22e347a8e9 300 SMART SM00028 69 102 3.7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1009350 a53a3b7835e637b2feaa0d22e347a8e9 300 SMART SM00028 103 136 0.0025 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1009350 a53a3b7835e637b2feaa0d22e347a8e9 300 PIRSF PIRSF004654 1 298 2.9E-104 T 13-10-2018 IPR023605 Lipoprotein NlpI MADE_1009350 a53a3b7835e637b2feaa0d22e347a8e9 300 Gene3D G3DSA:1.25.40.10 29 296 2.9E-75 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1009350 a53a3b7835e637b2feaa0d22e347a8e9 300 SUPERFAMILY SSF48452 36 289 2.0E-66 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006535 57069f6bf48b210530e394855f67d77a 405 Pfam PF12832 MFS_1 like family 24 377 3.8E-75 T 13-10-2018 IPR024989 Major facilitator superfamily associated domain MADE_1006535 57069f6bf48b210530e394855f67d77a 405 PIRSF PIRSF004925 17 405 9.3E-89 T 13-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter MADE_1006535 57069f6bf48b210530e394855f67d77a 405 Gene3D G3DSA:1.20.1250.20 207 403 4.5E-34 T 13-10-2018 MADE_1006535 57069f6bf48b210530e394855f67d77a 405 SUPERFAMILY SSF103473 21 399 6.45E-38 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1006535 57069f6bf48b210530e394855f67d77a 405 Gene3D G3DSA:1.20.1250.20 19 204 3.1E-15 T 13-10-2018 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 129 140 - T 13-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 Pfam PF00311 Phosphoenolpyruvate carboxylase 124 873 4.5E-271 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 2 873 17.498 T 13-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 Gene3D G3DSA:1.20.1440.90 297 381 1.0E-22 T 13-10-2018 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 240 255 1.4E-66 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 128 141 1.4E-66 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 701 727 1.4E-66 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 378 398 1.4E-66 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 569 598 1.4E-66 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 527 547 1.4E-66 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 181 197 1.4E-66 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 SUPERFAMILY SSF51621 11 873 5.02E-302 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MADE_000001023000 7a64b160d844a675d26f0c72212d05ee 873 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 529 541 - T 13-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 MADE_1011615 cd972b40f06a245c32b580d79962e0bf 97 Pfam PF07023 Protein of unknown function (DUF1315) 5 84 4.4E-27 T 13-10-2018 IPR009749 Protein of unknown function DUF1315 MADE_1010925 e83428b2027ac677af169b9871268ac8 269 Gene3D G3DSA:3.30.980.20 98 186 2.8E-80 T 13-10-2018 MADE_1010925 e83428b2027ac677af169b9871268ac8 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 184 230 1.1E-6 T 13-10-2018 MADE_1010925 e83428b2027ac677af169b9871268ac8 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 71 3.8E-11 T 13-10-2018 MADE_1010925 e83428b2027ac677af169b9871268ac8 269 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 5 267 3.6E-67 T 13-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 MADE_1010925 e83428b2027ac677af169b9871268ac8 269 Gene3D G3DSA:3.40.50.1000 5 259 2.8E-80 T 13-10-2018 IPR023214 HAD superfamily MADE_1010925 e83428b2027ac677af169b9871268ac8 269 SUPERFAMILY SSF56784 1 231 1.08E-45 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1010925 e83428b2027ac677af169b9871268ac8 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 231 4.1E-28 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MADE_1008065 c385ea4f26b89d754de5ee1885a18a93 357 Pfam PF11279 Protein of unknown function (DUF3080) 36 353 2.6E-88 T 13-10-2018 IPR021431 Protein of unknown function DUF3080 MADE_1008450 7d69005a7b5685160df2f0e0198a16c7 151 Gene3D G3DSA:1.10.1660.10 17 147 4.6E-27 T 13-10-2018 MADE_1008450 7d69005a7b5685160df2f0e0198a16c7 151 SMART SM00422 26 93 3.5E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1008450 7d69005a7b5685160df2f0e0198a16c7 151 Pfam PF09278 MerR, DNA binding 68 133 2.4E-16 T 13-10-2018 IPR015358 Transcription regulator MerR, DNA binding MADE_1008450 7d69005a7b5685160df2f0e0198a16c7 151 SUPERFAMILY SSF46955 26 140 6.59E-26 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1008450 7d69005a7b5685160df2f0e0198a16c7 151 Pfam PF00376 MerR family regulatory protein 28 62 9.6E-11 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1003745 266399bffc44b7af1c7b08cc8c12f1da 196 SUPERFAMILY SSF109604 5 186 2.2E-41 T 13-10-2018 MADE_1003745 266399bffc44b7af1c7b08cc8c12f1da 196 Gene3D G3DSA:1.10.3210.10 2 196 3.0E-51 T 13-10-2018 MADE_1003745 266399bffc44b7af1c7b08cc8c12f1da 196 Pfam PF13023 HD domain 15 178 1.2E-48 T 13-10-2018 IPR006674 HD domain MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 212 269 7.8E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 SUPERFAMILY SSF55874 262 423 2.36E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 Gene3D G3DSA:3.30.565.10 272 424 9.4E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 2.6E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 405 2.6E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 Gene3D G3DSA:1.10.287.130 161 271 1.1E-19 T 13-10-2018 MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 SMART SM00388 210 273 1.9E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 SUPERFAMILY SSF47384 194 271 4.9E-14 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 322 423 4.0E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1004125 85f3cb361298737dbe7f16ad966a4fb3 429 SMART SM00387 317 427 5.5E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001023645 2e9a593b4a9bc2f5e92955a3bef959b8 82 SUPERFAMILY SSF52922 4 63 1.07E-8 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_000001023645 2e9a593b4a9bc2f5e92955a3bef959b8 82 Gene3D G3DSA:3.40.50.920 2 70 2.4E-6 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1013895 4770f3024cadf404aed8d8269eb8be11 588 Gene3D G3DSA:3.30.1120.10 506 561 6.4E-101 T 13-10-2018 MADE_1013895 4770f3024cadf404aed8d8269eb8be11 588 SUPERFAMILY SSF53649 132 564 3.2E-101 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MADE_1013895 4770f3024cadf404aed8d8269eb8be11 588 Pfam PF00884 Sulfatase 133 474 7.2E-61 T 13-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 MADE_1013895 4770f3024cadf404aed8d8269eb8be11 588 Gene3D G3DSA:3.40.720.10 132 505 6.4E-101 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MADE_1013895 4770f3024cadf404aed8d8269eb8be11 588 ProSitePatterns PS00149 Sulfatases signature 2. 223 233 - T 13-10-2018 IPR024607 Sulfatase, conserved site MADE_1004170 f138473f4d7f633b0b7764f89ba6a28b 281 SUPERFAMILY SSF52540 2 153 9.0E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004170 f138473f4d7f633b0b7764f89ba6a28b 281 Gene3D G3DSA:3.40.50.300 1 163 6.6E-8 T 13-10-2018 MADE_1004170 f138473f4d7f633b0b7764f89ba6a28b 281 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 281 40.281 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 MADE_1004170 f138473f4d7f633b0b7764f89ba6a28b 281 PIRSF PIRSF005052 1 281 5.5E-106 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 MADE_1004170 f138473f4d7f633b0b7764f89ba6a28b 281 Pfam PF03668 P-loop ATPase protein family 2 280 2.5E-106 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 Gene3D G3DSA:3.40.50.720 14 312 4.2E-111 T 13-10-2018 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 Gene3D G3DSA:3.30.70.260 328 408 2.0E-32 T 13-10-2018 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 SUPERFAMILY SSF51735 108 295 1.4E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1014915 6e469512708618fbed66b4353b01fc02 409 SUPERFAMILY SSF55021 333 408 1.91E-16 T 13-10-2018 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MADE_1014915 6e469512708618fbed66b4353b01fc02 409 Gene3D G3DSA:3.40.50.720 109 297 4.2E-111 T 13-10-2018 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 326 1.2E-38 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 7.1E-53 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 SUPERFAMILY SSF52283 7 135 1.81E-50 T 13-10-2018 MADE_1014915 6e469512708618fbed66b4353b01fc02 409 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 229 245 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site MADE_1013760 b78f38d1e25bd4aab7de0ac39739cd46 414 Gene3D G3DSA:2.40.30.170 59 311 3.0E-55 T 13-10-2018 MADE_1013760 b78f38d1e25bd4aab7de0ac39739cd46 414 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 379 2.2E-45 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1013760 b78f38d1e25bd4aab7de0ac39739cd46 414 Gene3D G3DSA:2.40.50.100 69 214 3.0E-55 T 13-10-2018 MADE_1013760 b78f38d1e25bd4aab7de0ac39739cd46 414 Gene3D G3DSA:2.40.420.20 312 377 3.0E-55 T 13-10-2018 MADE_1013760 b78f38d1e25bd4aab7de0ac39739cd46 414 Gene3D G3DSA:1.10.287.470 106 180 3.0E-55 T 13-10-2018 MADE_1013760 b78f38d1e25bd4aab7de0ac39739cd46 414 Pfam PF13437 HlyD family secretion protein 183 292 7.9E-12 T 13-10-2018 MADE_1013760 b78f38d1e25bd4aab7de0ac39739cd46 414 SUPERFAMILY SSF111369 60 303 6.93E-23 T 13-10-2018 MADE_1008940 4437f6e1cf123996fc1425935c133338 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.461 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008940 4437f6e1cf123996fc1425935c133338 89 Pfam PF00312 Ribosomal protein S15 9 88 1.1E-36 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1008940 4437f6e1cf123996fc1425935c133338 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1008940 4437f6e1cf123996fc1425935c133338 89 Gene3D G3DSA:1.10.287.10 2 89 1.9E-35 T 13-10-2018 MADE_1008940 4437f6e1cf123996fc1425935c133338 89 SMART SM01387 8 88 7.3E-51 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1008940 4437f6e1cf123996fc1425935c133338 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.5E-38 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008940 4437f6e1cf123996fc1425935c133338 89 SUPERFAMILY SSF47060 3 89 6.18E-35 T 13-10-2018 IPR009068 S15/NS1, RNA-binding MADE_1008940 4437f6e1cf123996fc1425935c133338 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 6.0E-37 T 13-10-2018 MADE_1004215 af9c6afb9d427996e6453064dc128ec6 318 Gene3D G3DSA:1.20.1420.30 35 310 2.4E-84 T 13-10-2018 MADE_1004215 af9c6afb9d427996e6453064dc128ec6 318 Gene3D G3DSA:1.20.58.1130 8 205 2.4E-84 T 13-10-2018 MADE_1004215 af9c6afb9d427996e6453064dc128ec6 318 Pfam PF01699 Sodium/calcium exchanger protein 173 316 2.3E-30 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MADE_1004215 af9c6afb9d427996e6453064dc128ec6 318 Pfam PF01699 Sodium/calcium exchanger protein 5 143 4.1E-28 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 MADE_1004215 af9c6afb9d427996e6453064dc128ec6 318 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 312 9.5E-79 T 13-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 MADE_000001022545 1e639737a46799aba0c52d7cd6f584a8 462 SUPERFAMILY SSF52540 122 450 2.47E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022545 1e639737a46799aba0c52d7cd6f584a8 462 Gene3D G3DSA:3.40.50.10810 16 228 4.8E-25 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily MADE_000001022545 1e639737a46799aba0c52d7cd6f584a8 462 SUPERFAMILY SSF52540 5 233 9.61E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022545 1e639737a46799aba0c52d7cd6f584a8 462 Pfam PF00176 SNF2 family N-terminal domain 33 265 5.1E-19 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MADE_000001022545 1e639737a46799aba0c52d7cd6f584a8 462 Pfam PF00271 Helicase conserved C-terminal domain 313 414 4.7E-11 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_000001022545 1e639737a46799aba0c52d7cd6f584a8 462 SMART SM00487 7 191 4.4E-14 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_000001022545 1e639737a46799aba0c52d7cd6f584a8 462 Gene3D G3DSA:3.40.50.300 238 460 3.7E-28 T 13-10-2018 MADE_1000220 320d0df86cf6d470ab2654fb11d559e0 255 Gene3D G3DSA:3.90.550.10 1 159 7.4E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1000220 320d0df86cf6d470ab2654fb11d559e0 255 Pfam PF00535 Glycosyl transferase family 2 6 101 3.7E-17 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1000220 320d0df86cf6d470ab2654fb11d559e0 255 SUPERFAMILY SSF53448 3 137 4.03E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1005855 e5d17c63826f29943b8f20677e3aa6d4 214 SUPERFAMILY SSF53328 27 164 1.31E-19 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1005855 e5d17c63826f29943b8f20677e3aa6d4 214 Pfam PF00551 Formyl transferase 45 119 7.1E-7 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1005855 e5d17c63826f29943b8f20677e3aa6d4 214 Gene3D G3DSA:3.40.50.12230 18 214 1.7E-26 T 13-10-2018 MADE_1005855 e5d17c63826f29943b8f20677e3aa6d4 214 SUPERFAMILY SSF50486 167 207 1.33E-5 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 MADE_1012990 a9f66f9a9d5d276b7b73dec6108aed86 341 Gene3D G3DSA:3.40.50.720 101 225 2.7E-10 T 13-10-2018 MADE_1012990 a9f66f9a9d5d276b7b73dec6108aed86 341 Gene3D G3DSA:1.10.287.70 5 98 7.9E-15 T 13-10-2018 MADE_1012990 a9f66f9a9d5d276b7b73dec6108aed86 341 SUPERFAMILY SSF81324 12 124 3.14E-18 T 13-10-2018 MADE_1012990 a9f66f9a9d5d276b7b73dec6108aed86 341 Pfam PF07885 Ion channel 22 92 3.6E-12 T 13-10-2018 IPR013099 Potassium channel domain MADE_1012990 a9f66f9a9d5d276b7b73dec6108aed86 341 SUPERFAMILY SSF51735 110 234 6.99E-8 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 6 311 22.419 T 13-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 Gene3D G3DSA:3.40.50.620 16 235 6.5E-63 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 24 206 1.9E-52 T 13-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 SUPERFAMILY SSF56037 335 411 8.11E-9 T 13-10-2018 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 SUPERFAMILY SSF82829 240 319 6.15E-16 T 13-10-2018 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 SMART SM00977 360 431 0.0049 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 SUPERFAMILY SSF52402 23 234 6.92E-56 T 13-10-2018 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 Pfam PF01171 PP-loop family 24 203 6.3E-52 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 Gene3D G3DSA:1.20.59.20 238 321 1.3E-14 T 13-10-2018 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 Pfam PF09179 TilS substrate binding domain 254 317 2.7E-13 T 13-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MADE_1005400 710fe0dbf55de2627095d287d7dd983a 434 Pfam PF11734 TilS substrate C-terminal domain 360 412 1.3E-9 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 MADE_1004575 f59f1b785412184c93a33a866ee85c7a 394 Gene3D G3DSA:1.20.1720.10 16 392 2.4E-49 T 13-10-2018 MADE_1004575 f59f1b785412184c93a33a866ee85c7a 394 Pfam PF07690 Major Facilitator Superfamily 19 360 2.3E-19 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1004575 f59f1b785412184c93a33a866ee85c7a 394 SUPERFAMILY SSF103473 6 392 1.44E-31 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_000001021015 e175896ca7d43bf6a0cabdd70d30e668 130 SUPERFAMILY SSF158682 5 117 3.92E-10 T 13-10-2018 IPR029024 TerB-like MADE_000001021015 e175896ca7d43bf6a0cabdd70d30e668 130 Gene3D G3DSA:1.10.3680.10 1 121 4.8E-6 T 13-10-2018 IPR029024 TerB-like MADE_000001021015 e175896ca7d43bf6a0cabdd70d30e668 130 Pfam PF05099 Tellurite resistance protein TerB 7 112 1.1E-5 T 13-10-2018 IPR007791 Co-chaperone DjlA, N-terminal MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 Gene3D G3DSA:1.10.3810.10 168 371 1.1E-246 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 SUPERFAMILY SSF53955 176 368 2.36E-64 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 PIRSF PIRSF002799 3 786 0.0 T 13-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 Gene3D G3DSA:3.30.2060.10 78 167 1.1E-246 T 13-10-2018 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 Pfam PF14814 Bifunctional transglycosylase second domain 81 164 2.1E-18 T 13-10-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 36 753 1.0E-265 T 13-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 Gene3D G3DSA:3.40.710.10 70 726 1.1E-246 T 13-10-2018 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 Pfam PF00912 Transglycosylase 176 346 7.7E-56 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 Pfam PF00905 Penicillin binding protein transpeptidase domain 439 708 6.0E-22 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 MADE_1002390 b15d86da092b36aa896c39ff6fa94ef7 786 SUPERFAMILY SSF56601 329 768 3.69E-112 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 SUPERFAMILY SSF52540 454 633 6.93E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 SUPERFAMILY SSF52540 189 405 1.37E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 SMART SM00382 228 362 1.2E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 SMART SM00382 470 599 2.5E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 Gene3D G3DSA:3.40.50.300 186 375 3.0E-19 T 13-10-2018 MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 Gene3D G3DSA:3.40.50.300 430 620 1.1E-37 T 13-10-2018 MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 475 595 8.1E-29 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_1001440 e4f54ad3e1b3b6bd726ac5db6d6aefa5 676 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 232 359 8.4E-9 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 SUPERFAMILY SSF82866 803 1016 1.12E-44 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:3.30.70.1320 143 330 2.1E-277 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:1.20.1640.10 20 506 2.1E-277 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 SUPERFAMILY SSF82714 193 270 6.54E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:3.30.70.1430 561 656 2.1E-277 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:3.30.70.1440 657 852 2.1E-277 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 SUPERFAMILY SSF82693 50 143 2.09E-22 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Pfam PF00873 AcrB/AcrD/AcrF family 15 1012 9.7E-257 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 SUPERFAMILY SSF82866 296 493 8.89E-43 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:3.30.2090.10 188 274 2.1E-277 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:1.20.1640.10 507 1009 2.1E-277 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 SUPERFAMILY SSF82693 146 326 3.82E-15 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:3.30.70.1430 50 803 2.1E-277 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 SUPERFAMILY SSF82693 559 651 7.67E-17 T 13-10-2018 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 546 563 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 48 66 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 612 626 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 20 44 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 3.6E-66 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 Gene3D G3DSA:3.30.2090.10 707 795 2.1E-277 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_000001021025 adda0b8f92c9844a9e34928f979f040b 1038 SUPERFAMILY SSF82714 708 791 3.14E-17 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 2 192 7.9E-99 T 13-10-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 118 181 1.0E-23 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 Pfam PF01106 NifU-like domain 111 172 1.8E-17 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 SUPERFAMILY SSF89360 1 97 4.32E-23 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 SUPERFAMILY SSF117916 95 185 4.14E-22 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 Gene3D G3DSA:3.30.300.130 101 189 4.7E-18 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 192 44.408 T 13-10-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 Gene3D G3DSA:2.60.300.12 1 98 2.6E-15 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MADE_1020025 451e0d42268bdf90eff7bb8beec9dac1 192 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 98 2.4E-12 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MADE_1020420 045071802eed5ae889fc6016f7ef4c4f 398 Gene3D G3DSA:1.10.3210.10 3 319 2.2E-70 T 13-10-2018 MADE_1020420 045071802eed5ae889fc6016f7ef4c4f 398 Pfam PF11871 Domain of unknown function (DUF3391) 2 122 3.8E-15 T 13-10-2018 IPR021812 Protein of unknown function DUF3391 MADE_1020420 045071802eed5ae889fc6016f7ef4c4f 398 TIGRFAM TIGR00277 HDIG: HDIG domain 156 246 8.4E-9 T 13-10-2018 IPR006675 HDIG domain MADE_1020420 045071802eed5ae889fc6016f7ef4c4f 398 Pfam PF01966 HD domain 157 277 6.5E-18 T 13-10-2018 IPR006674 HD domain MADE_1020420 045071802eed5ae889fc6016f7ef4c4f 398 SUPERFAMILY SSF109604 149 317 9.65E-36 T 13-10-2018 MADE_1020420 045071802eed5ae889fc6016f7ef4c4f 398 SMART SM00471 152 287 4.4E-9 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1014980 041e44f681e7074d1098521977327703 891 SUPERFAMILY SSF52518 472 700 2.83E-98 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1014980 041e44f681e7074d1098521977327703 891 SUPERFAMILY SSF52922 705 890 3.05E-51 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1014980 041e44f681e7074d1098521977327703 891 Gene3D G3DSA:3.40.50.970 56 470 5.1E-132 T 13-10-2018 MADE_1014980 041e44f681e7074d1098521977327703 891 PIRSF PIRSF000156 1 891 0.0 T 13-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MADE_1014980 041e44f681e7074d1098521977327703 891 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 5 890 0.0 T 13-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 MADE_1014980 041e44f681e7074d1098521977327703 891 Gene3D G3DSA:3.40.50.970 471 705 1.3E-107 T 13-10-2018 MADE_1014980 041e44f681e7074d1098521977327703 891 Gene3D G3DSA:3.40.50.920 708 891 4.9E-67 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1014980 041e44f681e7074d1098521977327703 891 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 104 293 1.0E-9 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1014980 041e44f681e7074d1098521977327703 891 SUPERFAMILY SSF52518 57 467 1.18E-140 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1007925 60aeec64a64c0df85aa304b1b9b57d88 167 SUPERFAMILY SSF158694 2 165 8.76E-42 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MADE_1007925 60aeec64a64c0df85aa304b1b9b57d88 167 Pfam PF09349 OHCU decarboxylase 7 162 1.3E-34 T 13-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MADE_1007925 60aeec64a64c0df85aa304b1b9b57d88 167 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 6 165 3.4E-49 T 13-10-2018 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 MADE_1007925 60aeec64a64c0df85aa304b1b9b57d88 167 Gene3D G3DSA:1.10.3330.10 15 167 5.3E-51 T 13-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 MADE_1009525 54f2b12d0a8c2b9c02812defe8090b0d 1016 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 46 1015 1.8E-174 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_1009525 54f2b12d0a8c2b9c02812defe8090b0d 1016 Pfam PF00593 TonB dependent receptor 460 1015 4.9E-26 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1009525 54f2b12d0a8c2b9c02812defe8090b0d 1016 Pfam PF07715 TonB-dependent Receptor Plug Domain 72 168 8.1E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1009525 54f2b12d0a8c2b9c02812defe8090b0d 1016 SUPERFAMILY SSF56935 41 1015 2.75E-75 T 13-10-2018 MADE_1009525 54f2b12d0a8c2b9c02812defe8090b0d 1016 Gene3D G3DSA:2.170.130.10 56 172 3.2E-13 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1012200 1294b1664ef3569d6969bd58e7c7f790 98 Pfam PF05166 YcgL domain 3 75 9.9E-30 T 13-10-2018 IPR027354 YcgL domain MADE_1012200 1294b1664ef3569d6969bd58e7c7f790 98 Hamap MF_01866 Protein YcgL [ycgL]. 1 88 27.084 T 13-10-2018 IPR027354 YcgL domain MADE_1012200 1294b1664ef3569d6969bd58e7c7f790 98 Gene3D G3DSA:3.10.510.20 1 74 1.1E-28 T 13-10-2018 IPR038068 YcgL-like superfamily MADE_1012200 1294b1664ef3569d6969bd58e7c7f790 98 SUPERFAMILY SSF160191 1 92 2.35E-36 T 13-10-2018 IPR038068 YcgL-like superfamily MADE_1012200 1294b1664ef3569d6969bd58e7c7f790 98 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 1 82 2.0E-21 T 13-10-2018 IPR027354 YcgL domain MADE_1010715 6478481796306466c58f62092745522b 161 Gene3D G3DSA:1.10.10.10 3 60 1.3E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1010715 6478481796306466c58f62092745522b 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 56 9.4E-21 T 13-10-2018 MADE_1010715 6478481796306466c58f62092745522b 161 SMART SM00344 9 118 2.1E-48 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MADE_1010715 6478481796306466c58f62092745522b 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 2.4E-20 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1010715 6478481796306466c58f62092745522b 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 2.4E-20 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1010715 6478481796306466c58f62092745522b 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 2.4E-20 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1010715 6478481796306466c58f62092745522b 161 SUPERFAMILY SSF54909 71 156 1.14E-20 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel MADE_1010715 6478481796306466c58f62092745522b 161 SUPERFAMILY SSF46785 8 68 1.15E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1010715 6478481796306466c58f62092745522b 161 ProSitePatterns PS00519 AsnC-type HTH domain signature. 27 53 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MADE_1010715 6478481796306466c58f62092745522b 161 Gene3D G3DSA:3.30.70.920 61 155 8.4E-24 T 13-10-2018 MADE_1010715 6478481796306466c58f62092745522b 161 Pfam PF01037 Lrp/AsnC ligand binding domain 75 149 1.2E-20 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 TIGRFAM TIGR01529 argR_whole: arginine repressor 8 150 2.3E-43 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 88 129 2.0E-16 T 13-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 Hamap MF_00173 Arginine repressor [argR]. 1 154 60.331 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 SUPERFAMILY SSF46785 4 75 5.8E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 Pfam PF01316 Arginine repressor, DNA binding domain 4 73 1.1E-21 T 13-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 PRINTS PR01467 Bacterial arginine repressor signature 41 56 3.7E-23 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 PRINTS PR01467 Bacterial arginine repressor signature 24 37 3.7E-23 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 PRINTS PR01467 Bacterial arginine repressor signature 89 102 3.7E-23 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 PRINTS PR01467 Bacterial arginine repressor signature 120 135 3.7E-23 T 13-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 Gene3D G3DSA:3.30.1360.40 74 154 6.1E-31 T 13-10-2018 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 SUPERFAMILY SSF55252 81 150 1.02E-19 T 13-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 Gene3D G3DSA:1.10.10.10 1 73 6.0E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001023025 46595e62d7b35bdd3282ace75d4727cd 154 Pfam PF02863 Arginine repressor, C-terminal domain 81 148 7.2E-23 T 13-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 MADE_1007475 ab543a107e5d2a79e329a5e0329a4d47 210 Pfam PF10531 SLBB domain 125 174 3.1E-6 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1007475 ab543a107e5d2a79e329a5e0329a4d47 210 Gene3D G3DSA:3.30.1950.10 51 119 4.3E-12 T 13-10-2018 MADE_1007475 ab543a107e5d2a79e329a5e0329a4d47 210 TIGRFAM TIGR03027 pepcterm_export: putative polysaccharide export protein, PEP-CTERM sytem-associated 46 210 1.3E-67 T 13-10-2018 IPR017477 PEP-CTERM, putative polysaccharide export protein MADE_1007475 ab543a107e5d2a79e329a5e0329a4d47 210 Pfam PF02563 Polysaccharide biosynthesis/export protein 42 115 4.7E-20 T 13-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MADE_1007475 ab543a107e5d2a79e329a5e0329a4d47 210 Gene3D G3DSA:3.10.560.10 120 207 6.3E-17 T 13-10-2018 MADE_1014160 533ca66893a40d2994980133c8211e03 317 PIRSF PIRSF035875 5 306 1.2E-68 T 13-10-2018 IPR017039 Virulence factor BrkB MADE_1014160 533ca66893a40d2994980133c8211e03 317 Pfam PF03631 Virulence factor BrkB 33 285 8.5E-61 T 13-10-2018 IPR017039 Virulence factor BrkB MADE_1014160 533ca66893a40d2994980133c8211e03 317 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 24 284 6.2E-32 T 13-10-2018 IPR017039 Virulence factor BrkB MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 PRINTS PR00723 Subtilisin serine protease family (S8) signature 264 277 5.2E-17 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 PRINTS PR00723 Subtilisin serine protease family (S8) signature 191 210 5.2E-17 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 PRINTS PR00723 Subtilisin serine protease family (S8) signature 608 624 5.2E-17 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 Gene3D G3DSA:3.40.50.200 193 679 6.5E-102 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 Pfam PF05922 Peptidase inhibitor I9 93 164 6.3E-6 T 13-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 268 278 - T 13-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 Gene3D G3DSA:2.60.40.10 1210 1294 2.8E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 196 207 - T 13-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 PIRSF PIRSF037898 1 1319 8.7E-249 T 13-10-2018 IPR017312 Peptidase S8A, subtilisin-related, Alteromonadales MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 609 619 - T 13-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 Pfam PF02225 PA domain 439 531 2.0E-11 T 13-10-2018 IPR003137 PA domain MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 SUPERFAMILY SSF52743 168 674 9.03E-67 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 Pfam PF00082 Subtilase family 191 665 4.0E-50 T 13-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 SUPERFAMILY SSF52025 436 520 6.02E-10 T 13-10-2018 MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 Gene3D G3DSA:3.50.30.30 403 555 6.5E-102 T 13-10-2018 MADE_1009890 9e23b66471b2f3bbf2cb6b4e198dfb20 1321 TIGRFAM TIGR03501 GlyGly_CTERM: GlyGly-CTERM domain 1297 1317 3.5E-5 T 13-10-2018 IPR020008 GlyGly-CTERM domain MADE_1000085 ad60ef026efe0c3b5000674d0b6d123b 483 Pfam PF02386 Cation transport protein 39 477 1.8E-84 T 13-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 MADE_1000085 ad60ef026efe0c3b5000674d0b6d123b 483 PIRSF PIRSF006247 1 483 4.9E-178 T 13-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 MADE_1000085 ad60ef026efe0c3b5000674d0b6d123b 483 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 466 1.1E-110 T 13-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 Pfam PF00149 Calcineurin-like phosphoesterase 6 141 2.4E-15 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 Gene3D G3DSA:3.60.21.10 5 275 1.6E-73 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 6 264 1.2E-86 T 13-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 PRINTS PR00114 Serine/threonine phosphatase family signature 5 32 2.5E-6 T 13-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 PRINTS PR00114 Serine/threonine phosphatase family signature 35 62 2.5E-6 T 13-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 PRINTS PR00114 Serine/threonine phosphatase family signature 103 129 2.5E-6 T 13-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 PIRSF PIRSF000903 4 275 1.7E-101 T 13-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 MADE_1003970 9bf2763002ae47764e274476cfe45ab9 275 SUPERFAMILY SSF56300 4 263 5.84E-54 T 13-10-2018 MADE_1002970 bb0bce811c1e33f56986db6acc85efef 356 SUPERFAMILY SSF50182 109 170 1.57E-11 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1002970 bb0bce811c1e33f56986db6acc85efef 356 Pfam PF00924 Mechanosensitive ion channel 66 259 1.2E-17 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1002970 bb0bce811c1e33f56986db6acc85efef 356 Gene3D G3DSA:2.30.30.60 124 171 1.5E-7 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1002970 bb0bce811c1e33f56986db6acc85efef 356 SUPERFAMILY SSF82689 180 263 3.14E-5 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1012650 05ea5cbd3eb15287cba0220aa2360a82 155 Gene3D G3DSA:3.10.50.40 16 144 2.3E-40 T 13-10-2018 MADE_1012650 05ea5cbd3eb15287cba0220aa2360a82 155 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 10 143 5.8E-13 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MADE_1012650 05ea5cbd3eb15287cba0220aa2360a82 155 SUPERFAMILY SSF54534 9 146 3.34E-35 T 13-10-2018 MADE_1012650 05ea5cbd3eb15287cba0220aa2360a82 155 Gene3D G3DSA:2.40.10.330 75 131 2.3E-40 T 13-10-2018 MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 Pfam PF01339 CheB methylesterase 191 370 1.2E-59 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 Gene3D G3DSA:3.40.50.2300 3 131 1.9E-32 T 13-10-2018 MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 SUPERFAMILY SSF52738 185 372 4.45E-61 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 Gene3D G3DSA:3.40.50.180 183 373 4.6E-64 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 SMART SM00448 3 126 3.6E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 Pfam PF00072 Response regulator receiver domain 5 109 7.9E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 SUPERFAMILY SSF52172 3 109 8.68E-27 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 376 37.961 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1006005 84aab0f9de2801b4e2d2d5cfa98460d0 376 PIRSF PIRSF000876 1 376 9.5E-127 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 SUPERFAMILY SSF48498 98 222 1.42E-38 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 2.7E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 2.7E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 SUPERFAMILY SSF46689 23 101 1.21E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 Pfam PF08362 YcdC-like protein, C-terminal region 82 222 6.6E-55 T 13-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 Gene3D G3DSA:1.10.357.10 81 223 6.6E-49 T 13-10-2018 MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 8.7E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_000001022915 6f0b329dbfd19e4c1181e8bb55ad3e66 223 Gene3D G3DSA:1.10.10.60 14 80 1.8E-20 T 13-10-2018 MADE_1013000 9d0d9dc8c8767056d94c1b0aa373b56a 138 Pfam PF03994 Domain of Unknown Function (DUF350) 83 136 1.9E-12 T 13-10-2018 IPR007140 Protein of unknown function DUF350 MADE_1013000 9d0d9dc8c8767056d94c1b0aa373b56a 138 Pfam PF03994 Domain of Unknown Function (DUF350) 17 70 2.9E-12 T 13-10-2018 IPR007140 Protein of unknown function DUF350 MADE_1004780 956ddd67c199b41ee9577cefcbfc0759 164 SUPERFAMILY SSF82093 30 141 7.85E-39 T 13-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 MADE_1004780 956ddd67c199b41ee9577cefcbfc0759 164 Pfam PF03100 CcmE 4 135 6.2E-44 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 MADE_1004780 956ddd67c199b41ee9577cefcbfc0759 164 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 145 31.21 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 MADE_1004780 956ddd67c199b41ee9577cefcbfc0759 164 Gene3D G3DSA:2.40.50.140 30 141 1.6E-39 T 13-10-2018 MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 Gene3D G3DSA:1.10.10.10 2 88 1.1E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.7E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.7E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.7E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 SUPERFAMILY SSF46785 5 89 1.09E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 9.6E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 Pfam PF03466 LysR substrate binding domain 93 289 2.0E-29 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 SUPERFAMILY SSF53850 93 293 3.0E-29 T 13-10-2018 MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 Gene3D G3DSA:3.40.190.10 164 264 9.3E-47 T 13-10-2018 MADE_1004420 1f3d851ba6c715482bf7753e69108958 302 Gene3D G3DSA:3.40.190.10 94 292 9.3E-47 T 13-10-2018 MADE_1009360 dc918f527b5d2730e0af5d4008a4f53c 245 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 8 225 9.7E-37 T 13-10-2018 MADE_1009360 dc918f527b5d2730e0af5d4008a4f53c 245 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 2 243 27.818 T 13-10-2018 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 SMART SM00421 234 291 9.3E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 Gene3D G3DSA:3.40.50.12740 7 166 8.5E-40 T 13-10-2018 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 Pfam PF00072 Response regulator receiver domain 8 118 1.0E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 SUPERFAMILY SSF52172 8 125 1.99E-38 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 237 251 6.4E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 251 267 6.4E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 267 279 6.4E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 SMART SM00448 6 117 3.7E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 Pfam PF00196 Bacterial regulatory proteins, luxR family 237 291 1.3E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 SUPERFAMILY SSF46894 231 293 6.12E-16 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1014335 c6712f7eddd3620612ab6ae671eab0f7 298 Gene3D G3DSA:1.10.10.10 230 295 1.2E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016425 7d69a57f66d8630f50ac08b62d6dcde4 495 Pfam PF05231 MASE1 13 289 3.7E-11 T 13-10-2018 IPR007895 MASE1 MADE_1016425 7d69a57f66d8630f50ac08b62d6dcde4 495 Gene3D G3DSA:3.90.850.10 282 491 1.8E-33 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MADE_1016425 7d69a57f66d8630f50ac08b62d6dcde4 495 SUPERFAMILY SSF56529 288 489 4.97E-22 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MADE_1013690 bd54a9d0376f3eeecb6d70f32624c63a 413 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 410 2.2E-101 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MADE_1013690 bd54a9d0376f3eeecb6d70f32624c63a 413 Gene3D G3DSA:3.40.640.10 2 276 2.1E-65 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1013690 bd54a9d0376f3eeecb6d70f32624c63a 413 SUPERFAMILY SSF53383 38 411 3.63E-88 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1013690 bd54a9d0376f3eeecb6d70f32624c63a 413 PIRSF PIRSF001434 2 413 1.1E-110 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MADE_1013690 bd54a9d0376f3eeecb6d70f32624c63a 413 Gene3D G3DSA:3.90.1150.10 277 413 1.4E-40 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1014995 83eebc25908cf8af5a9c5a4cb9f904f2 178 Gene3D G3DSA:3.40.80.10 2 178 6.3E-55 T 13-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MADE_1014995 83eebc25908cf8af5a9c5a4cb9f904f2 178 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 163 3.4E-25 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MADE_1014995 83eebc25908cf8af5a9c5a4cb9f904f2 178 SUPERFAMILY SSF55846 4 175 3.27E-62 T 13-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MADE_1014995 83eebc25908cf8af5a9c5a4cb9f904f2 178 SMART SM00644 12 163 3.4E-49 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 PRINTS PR00946 Mercury scavenger protein signature 93 107 1.2E-19 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 PRINTS PR00946 Mercury scavenger protein signature 64 79 1.2E-19 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 PRINTS PR00946 Mercury scavenger protein signature 37 48 1.2E-19 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 PRINTS PR00946 Mercury scavenger protein signature 48 64 1.2E-19 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 PRINTS PR00946 Mercury scavenger protein signature 79 93 1.2E-19 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 Pfam PF00403 Heavy-metal-associated domain 42 102 4.7E-13 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 SUPERFAMILY SSF55008 36 105 1.05E-19 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MADE_1005545 9c3d41a12cfc47cdf55684a8c5130dae 108 Gene3D G3DSA:3.30.70.100 38 106 5.5E-18 T 13-10-2018 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 240 8.3E-19 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 Gene3D G3DSA:1.20.140.10 254 409 1.8E-39 T 13-10-2018 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 Gene3D G3DSA:2.40.110.10 139 253 2.7E-48 T 13-10-2018 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 Gene3D G3DSA:1.10.540.10 1 138 1.1E-53 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 403 2.6E-37 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 136 1.0E-17 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 SUPERFAMILY SSF56645 2 266 4.97E-70 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1013470 b6550d15d36cc1a0cf66d4b946e69bbd 411 SUPERFAMILY SSF47203 251 406 4.51E-44 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 148 8.0E-42 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 SUPERFAMILY SSF52788 2 152 3.92E-51 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 SMART SM00226 5 151 5.9E-49 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 4.8E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 4.8E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 4.8E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 7 24 4.8E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 MADE_1007280 ba72263d3d0d7c2dde9388adea7250c4 157 Gene3D G3DSA:3.40.50.2300 4 157 2.0E-58 T 13-10-2018 MADE_1000650 b356853c5893100faab54a5a0afeb335 697 Gene3D G3DSA:2.170.130.10 42 166 9.5E-30 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1000650 b356853c5893100faab54a5a0afeb335 697 SUPERFAMILY SSF56935 33 697 1.58E-111 T 13-10-2018 MADE_1000650 b356853c5893100faab54a5a0afeb335 697 Pfam PF00593 TonB dependent receptor 236 696 7.8E-33 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1000650 b356853c5893100faab54a5a0afeb335 697 Gene3D G3DSA:2.40.170.20 167 697 2.1E-126 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1000650 b356853c5893100faab54a5a0afeb335 697 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 61 697 1.4E-78 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MADE_1000650 b356853c5893100faab54a5a0afeb335 697 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 159 6.8E-12 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1013580 71b0fd58524c545697b2118e03b02411 393 Pfam PF00155 Aminotransferase class I and II 62 388 1.2E-44 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1013580 71b0fd58524c545697b2118e03b02411 393 Gene3D G3DSA:3.40.640.10 76 296 1.4E-85 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1013580 71b0fd58524c545697b2118e03b02411 393 Gene3D G3DSA:3.90.1150.10 60 380 1.4E-85 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1013580 71b0fd58524c545697b2118e03b02411 393 SUPERFAMILY SSF53383 59 392 1.34E-71 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1005865 51faf59a3ab157c03818c06081f580a7 389 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 380 3.6E-107 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MADE_1005865 51faf59a3ab157c03818c06081f580a7 389 PIRSF PIRSF000390 1 388 4.3E-107 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MADE_1005865 51faf59a3ab157c03818c06081f580a7 389 SUPERFAMILY SSF53383 2 385 1.99E-112 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1005865 51faf59a3ab157c03818c06081f580a7 389 Gene3D G3DSA:3.90.1150.10 261 387 2.4E-35 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1005865 51faf59a3ab157c03818c06081f580a7 389 Gene3D G3DSA:3.40.640.10 1 259 1.4E-88 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1005865 51faf59a3ab157c03818c06081f580a7 389 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 1 383 7.0E-165 T 13-10-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase MADE_1000455 dd3bac75f0f847067d1785bd9ec0569a 333 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 323 1.9E-94 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MADE_1000455 dd3bac75f0f847067d1785bd9ec0569a 333 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 7 328 1.9E-42 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MADE_000001022970 c5469a41fa90c406b595e2b7e516ee21 210 Pfam PF02508 Rnf-Nqr subunit, membrane protein 8 195 1.7E-58 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_000001022970 c5469a41fa90c406b595e2b7e516ee21 210 PIRSF PIRSF006102 3 210 1.9E-67 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 MADE_000001022970 c5469a41fa90c406b595e2b7e516ee21 210 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 2 207 35.853 T 13-10-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MADE_000001022970 c5469a41fa90c406b595e2b7e516ee21 210 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 4 207 1.4E-99 T 13-10-2018 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 MADE_1000815 2f145df958dae1f296de75e45155e21a 344 SUPERFAMILY SSF52540 1 233 6.63E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000815 2f145df958dae1f296de75e45155e21a 344 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1000815 2f145df958dae1f296de75e45155e21a 344 SUPERFAMILY SSF50331 253 331 1.08E-6 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal MADE_1000815 2f145df958dae1f296de75e45155e21a 344 Pfam PF00005 ABC transporter 18 154 7.0E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1000815 2f145df958dae1f296de75e45155e21a 344 Gene3D G3DSA:3.40.50.300 1 214 9.0E-53 T 13-10-2018 MADE_1000815 2f145df958dae1f296de75e45155e21a 344 SMART SM00382 26 203 1.9E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1000815 2f145df958dae1f296de75e45155e21a 344 Pfam PF08402 TOBE domain 269 330 1.1E-6 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 MADE_1000815 2f145df958dae1f296de75e45155e21a 344 Gene3D G3DSA:2.40.50.940 215 275 8.1E-9 T 13-10-2018 MADE_1000815 2f145df958dae1f296de75e45155e21a 344 Gene3D G3DSA:2.40.50.140 276 330 8.1E-9 T 13-10-2018 MADE_1015500 ee7a8c3f1957dee49786d93bd275fdbd 228 SUPERFAMILY SSF52799 72 201 1.66E-10 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like MADE_1015500 ee7a8c3f1957dee49786d93bd275fdbd 228 Gene3D G3DSA:3.90.190.10 60 211 7.5E-31 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 SMART SM00830 34 114 2.6E-26 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 Pfam PF00800 Prephenate dehydratase 130 311 3.2E-55 T 13-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 SUPERFAMILY SSF48600 29 115 1.68E-22 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 Gene3D G3DSA:3.30.70.260 315 403 1.5E-26 T 13-10-2018 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 SUPERFAMILY SSF53850 129 314 1.41E-50 T 13-10-2018 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 Gene3D G3DSA:3.40.190.10 133 307 4.9E-49 T 13-10-2018 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 Gene3D G3DSA:3.40.190.10 213 298 4.9E-49 T 13-10-2018 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 SUPERFAMILY SSF55021 304 401 5.95E-26 T 13-10-2018 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 PIRSF PIRSF001500 23 404 1.6E-126 T 13-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 Pfam PF01817 Chorismate mutase type II 34 111 2.6E-18 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 TIGRFAM TIGR01797 CM_P_1: chorismate mutase 31 112 2.1E-24 T 13-10-2018 IPR010952 Chorismate mutase, gammaproteobacteria GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 349 356 - T 13-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 MADE_000001021090 b619b9cb7733cea53c0d324d83947ee1 417 Gene3D G3DSA:1.20.59.10 25 132 8.2E-32 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 MADE_1009730 9fb9abf6e6b5471fc0afe6e7b8bbeaf7 151 Gene3D G3DSA:3.10.129.10 4 135 5.0E-50 T 13-10-2018 MADE_1009730 9fb9abf6e6b5471fc0afe6e7b8bbeaf7 151 Pfam PF03061 Thioesterase superfamily 45 118 3.4E-13 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MADE_1009730 9fb9abf6e6b5471fc0afe6e7b8bbeaf7 151 SUPERFAMILY SSF54637 4 135 4.06E-25 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1007650 cfc37e398899938cd3650790f9441447 285 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 189 195 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1007650 cfc37e398899938cd3650790f9441447 285 Gene3D G3DSA:3.40.50.150 86 284 5.5E-62 T 13-10-2018 MADE_1007650 cfc37e398899938cd3650790f9441447 285 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 284 4.7E-82 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MADE_1007650 cfc37e398899938cd3650790f9441447 285 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 280 1.7E-91 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MADE_1007650 cfc37e398899938cd3650790f9441447 285 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 284 43.047 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 MADE_1007650 cfc37e398899938cd3650790f9441447 285 Gene3D G3DSA:1.10.8.10 1 83 3.5E-24 T 13-10-2018 MADE_1007650 cfc37e398899938cd3650790f9441447 285 SUPERFAMILY SSF53335 3 282 4.89E-61 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1007650 cfc37e398899938cd3650790f9441447 285 Pfam PF13847 Methyltransferase domain 119 248 8.2E-21 T 13-10-2018 IPR025714 Methyltransferase domain MADE_1013805 9d91df36d20db8287a5c870fb6feefda 288 SUPERFAMILY SSF51735 1 284 1.85E-91 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013805 9d91df36d20db8287a5c870fb6feefda 288 Gene3D G3DSA:3.40.50.720 3 271 3.1E-97 T 13-10-2018 MADE_1013805 9d91df36d20db8287a5c870fb6feefda 288 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 283 4.8E-96 T 13-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MADE_1013805 9d91df36d20db8287a5c870fb6feefda 288 Pfam PF04321 RmlD substrate binding domain 1 284 1.1E-94 T 13-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 MADE_1013805 9d91df36d20db8287a5c870fb6feefda 288 Gene3D G3DSA:3.90.25.10 157 278 3.1E-97 T 13-10-2018 MADE_1000225 6bf47ffa6b2b3a32c558652116e97d33 195 Gene3D G3DSA:1.10.357.10 7 194 8.6E-64 T 13-10-2018 MADE_1000225 6bf47ffa6b2b3a32c558652116e97d33 195 SUPERFAMILY SSF46689 5 76 8.48E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1000225 6bf47ffa6b2b3a32c558652116e97d33 195 Hamap MF_01839 Nucleoid occlusion factor SlmA [slmA]. 1 195 41.638 T 13-10-2018 IPR023769 Nucleoid occlusion factor SlmA GO:0010974 MADE_1000225 6bf47ffa6b2b3a32c558652116e97d33 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 57 8.3E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1019180 6cdaf5b40d7f24b7e7caf6339172d273 184 Pfam PF01292 Prokaryotic cytochrome b561 13 181 5.5E-29 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MADE_1019180 6cdaf5b40d7f24b7e7caf6339172d273 184 SUPERFAMILY SSF81342 7 181 3.22E-36 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MADE_1016225 f62864e00972fbe75f74b35de25a8bf6 236 Gene3D G3DSA:3.90.226.10 20 212 5.1E-9 T 13-10-2018 MADE_1016225 f62864e00972fbe75f74b35de25a8bf6 236 SUPERFAMILY SSF52096 28 140 1.89E-10 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 SUPERFAMILY SSF55874 286 450 3.54E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 Gene3D G3DSA:3.30.565.10 298 449 2.9E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 Gene3D G3DSA:1.10.287.130 182 297 8.6E-22 T 13-10-2018 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 295 1.2E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 SMART SM00388 234 296 4.3E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 SUPERFAMILY SSF47384 217 295 3.73E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 449 7.0E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 4.1E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 4.1E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 4.1E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 4.1E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1014065 47b6c24bfe7fd4907ee8b88357e2dfa4 458 SMART SM00387 341 451 4.9E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001023510 d18b16a0d62f75bcd6620164b5988e14 475 Pfam PF00171 Aldehyde dehydrogenase family 18 468 3.1E-146 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_000001023510 d18b16a0d62f75bcd6620164b5988e14 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MADE_000001023510 d18b16a0d62f75bcd6620164b5988e14 475 Gene3D G3DSA:3.40.309.10 252 440 2.9E-158 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_000001023510 d18b16a0d62f75bcd6620164b5988e14 475 SUPERFAMILY SSF53720 19 472 1.05E-138 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_000001023510 d18b16a0d62f75bcd6620164b5988e14 475 Gene3D G3DSA:3.40.605.10 27 461 2.9E-158 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1007970 6fa19b248163db5d4a18ef6dfb2fb575 120 SUPERFAMILY SSF47226 13 119 7.2E-20 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1007970 6fa19b248163db5d4a18ef6dfb2fb575 120 Gene3D G3DSA:1.20.120.160 7 120 1.8E-18 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1007970 6fa19b248163db5d4a18ef6dfb2fb575 120 Pfam PF01627 Hpt domain 35 111 9.0E-9 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 Gene3D G3DSA:3.40.1190.10 15 309 3.1E-86 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 Pfam PF08245 Mur ligase middle domain 69 216 9.8E-12 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 Gene3D G3DSA:3.90.190.20 310 443 7.2E-28 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 SUPERFAMILY SSF53244 309 440 2.56E-26 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 SUPERFAMILY SSF53623 25 306 2.01E-78 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 164 179 - T 13-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 PIRSF PIRSF001563 21 443 4.0E-98 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MADE_1011890 e76e553f4a872419a6978790de7ac50c 443 TIGRFAM TIGR01499 folC: bifunctional protein FolC 47 440 6.0E-95 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 MADE_000001023495 6a4e974cd3d12aa6305d0c21cef99099 324 Gene3D G3DSA:3.40.50.1820 37 324 3.7E-81 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001023495 6a4e974cd3d12aa6305d0c21cef99099 324 Pfam PF00561 alpha/beta hydrolase fold 45 156 7.3E-12 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_000001023495 6a4e974cd3d12aa6305d0c21cef99099 324 SUPERFAMILY SSF53474 40 303 1.12E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1016870 6fb935f2f28e860f623636abcf8b765f 91 Pfam PF14452 Multiubiquitin 17 88 6.5E-16 T 13-10-2018 IPR027802 Multi-ubiquitin domain MADE_1010815 86a4d20691d347c6677d90e15dd0bc5b 367 Hamap MF_00924 Outer membrane protein assembly factor BamC [bamC]. 2 361 37.99 T 13-10-2018 IPR014524 Outer membrane protein assembly factor BamC MADE_1010815 86a4d20691d347c6677d90e15dd0bc5b 367 Pfam PF06804 NlpB/DapX lipoprotein 33 360 1.2E-100 T 13-10-2018 IPR010653 NlpB/DapX lipoprotein MADE_1010815 86a4d20691d347c6677d90e15dd0bc5b 367 Gene3D G3DSA:3.30.310.170 243 366 1.8E-36 T 13-10-2018 MADE_1012085 bdd0487559761edcdf44f9d7966ec6ad 148 Pfam PF03061 Thioesterase superfamily 29 96 2.4E-8 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MADE_1012085 bdd0487559761edcdf44f9d7966ec6ad 148 SUPERFAMILY SSF54637 8 146 5.04E-32 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1012085 bdd0487559761edcdf44f9d7966ec6ad 148 Gene3D G3DSA:3.10.129.10 7 143 3.7E-28 T 13-10-2018 MADE_1001915 16237de6d60f1c763436204d78b5d85c 144 Pfam PF00376 MerR family regulatory protein 3 38 1.1E-6 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1001915 16237de6d60f1c763436204d78b5d85c 144 Gene3D G3DSA:1.10.1660.10 1 119 6.9E-26 T 13-10-2018 MADE_1001915 16237de6d60f1c763436204d78b5d85c 144 Pfam PF09278 MerR, DNA binding 44 103 6.8E-15 T 13-10-2018 IPR015358 Transcription regulator MerR, DNA binding MADE_1001915 16237de6d60f1c763436204d78b5d85c 144 SUPERFAMILY SSF46955 1 105 2.2E-24 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1001915 16237de6d60f1c763436204d78b5d85c 144 SMART SM00422 1 69 6.0E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1014040 28ba069edee5b173ea21de347ebba32e 227 SMART SM00953 68 204 2.2E-10 T 13-10-2018 IPR014914 RES domain MADE_1014040 28ba069edee5b173ea21de347ebba32e 227 Pfam PF08808 RES domain 65 210 3.0E-20 T 13-10-2018 IPR014914 RES domain MADE_000001022975 ffb582ee751cc27e7bda0477f2373886 254 PIRSF PIRSF009437 1 253 2.1E-85 T 13-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 MADE_000001022975 ffb582ee751cc27e7bda0477f2373886 254 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 6 249 2.4E-77 T 13-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 MADE_000001022975 ffb582ee751cc27e7bda0477f2373886 254 SMART SM00900 145 241 1.8E-26 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MADE_000001022975 ffb582ee751cc27e7bda0477f2373886 254 Pfam PF04205 FMN-binding domain 145 237 3.7E-13 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 MADE_000001022975 ffb582ee751cc27e7bda0477f2373886 254 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 6 251 34.152 T 13-10-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0010181|GO:0016021|GO:0016655 MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 SUPERFAMILY SSF55021 2 76 3.44E-22 T 13-10-2018 MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 Gene3D G3DSA:3.30.70.1150 80 158 3.5E-26 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 Pfam PF13710 ACT domain 11 73 1.2E-16 T 13-10-2018 MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 Pfam PF10369 Small subunit of acetolactate synthase 84 159 3.7E-24 T 13-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 Gene3D G3DSA:3.30.70.260 1 78 4.8E-34 T 13-10-2018 MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 160 1.8E-59 T 13-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 SUPERFAMILY SSF55021 79 163 6.34E-25 T 13-10-2018 MADE_1002795 d59464cea389c438d9398ad5edb61c02 165 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-33 T 13-10-2018 MADE_1005225 2296b4aa809f3e3c8aa106c42450e737 206 PIRSF PIRSF006170 1 206 4.2E-58 T 13-10-2018 IPR026039 Uncharacterised protein family UPF0070 MADE_1005225 2296b4aa809f3e3c8aa106c42450e737 206 SUPERFAMILY SSF48452 92 195 3.0E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1005225 2296b4aa809f3e3c8aa106c42450e737 206 Pfam PF09976 Tetratricopeptide repeat-like domain 15 201 1.1E-59 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 MADE_1005225 2296b4aa809f3e3c8aa106c42450e737 206 SMART SM00028 157 190 0.008 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1005225 2296b4aa809f3e3c8aa106c42450e737 206 Gene3D G3DSA:1.25.40.10 38 205 8.1E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1000675 496bebb6dcc3f82ec324ea4c23568217 479 Pfam PF04317 YcjX-like family, DUF463 49 474 3.2E-77 T 13-10-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein MADE_1005910 e37672b6edb36a57ea87f81e5d36908c 260 PRINTS PR01003 Flagellar assembly protein FliH signature 80 102 8.6E-11 T 13-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MADE_1005910 e37672b6edb36a57ea87f81e5d36908c 260 PRINTS PR01003 Flagellar assembly protein FliH signature 212 228 8.6E-11 T 13-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MADE_1005910 e37672b6edb36a57ea87f81e5d36908c 260 PRINTS PR01003 Flagellar assembly protein FliH signature 142 159 8.6E-11 T 13-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MADE_1005910 e37672b6edb36a57ea87f81e5d36908c 260 PRINTS PR01003 Flagellar assembly protein FliH signature 103 121 8.6E-11 T 13-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 MADE_1005910 e37672b6edb36a57ea87f81e5d36908c 260 Pfam PF02108 Flagellar assembly protein FliH 121 246 3.7E-33 T 13-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 Gene3D G3DSA:3.40.50.10330 235 365 1.4E-31 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 Gene3D G3DSA:3.90.190.10 87 233 4.8E-29 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 SMART SM00046 240 374 5.4E-11 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 Gene3D G3DSA:2.60.200.40 366 530 1.8E-28 T 13-10-2018 MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 SMART SM00195 90 229 3.4E-22 T 13-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 Pfam PF00782 Dual specificity phosphatase, catalytic domain 98 227 3.5E-20 T 13-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 Pfam PF00781 Diacylglycerol kinase catalytic domain 240 365 2.0E-27 T 13-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 SUPERFAMILY SSF111331 239 536 8.99E-58 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MADE_000001021935 c64da63c76b965d56a6e2344d45d2ce4 542 SUPERFAMILY SSF52799 84 229 6.53E-30 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 3.3E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 3.3E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 3.3E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 3.3E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 Gene3D G3DSA:3.40.50.1000 8 205 3.6E-21 T 13-10-2018 IPR023214 HAD superfamily MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 SUPERFAMILY SSF56784 5 217 4.33E-39 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 193 8.9E-10 T 13-10-2018 MADE_1019895 9b2f0b357008b1fbc4de870d2c346d6e 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 191 2.5E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 324 9.6E-64 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 343 449 2.0E-28 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 SUPERFAMILY SSF51905 1 363 4.8E-56 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 Gene3D G3DSA:3.50.50.60 9 324 2.5E-113 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 Gene3D G3DSA:3.50.50.60 152 268 2.5E-113 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PRINTS PR00945 Mercuric reductase class II signature 199 214 7.4E-73 T 13-10-2018 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PRINTS PR00945 Mercuric reductase class II signature 179 196 7.4E-73 T 13-10-2018 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PRINTS PR00945 Mercuric reductase class II signature 52 71 7.4E-73 T 13-10-2018 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PRINTS PR00945 Mercuric reductase class II signature 440 459 7.4E-73 T 13-10-2018 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PRINTS PR00945 Mercuric reductase class II signature 144 161 7.4E-73 T 13-10-2018 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PRINTS PR00945 Mercuric reductase class II signature 17 35 7.4E-73 T 13-10-2018 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PRINTS PR00945 Mercuric reductase class II signature 375 395 7.4E-73 T 13-10-2018 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 SUPERFAMILY SSF55424 339 465 1.05E-31 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 Gene3D G3DSA:3.30.390.30 342 467 2.0E-43 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 PIRSF PIRSF000350 1 467 3.2E-227 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MADE_1005590 328c42a9e3c9567f1617829c067bed0c 467 TIGRFAM TIGR02053 MerA: mercury(II) reductase 7 467 1.4E-180 T 13-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 MADE_1005365 fa75e14bd25519ecce71cf3bd9df1f71 171 SUPERFAMILY SSF111384 25 167 6.54E-32 T 13-10-2018 MADE_1005365 fa75e14bd25519ecce71cf3bd9df1f71 171 Pfam PF03938 Outer membrane protein (OmpH-like) 13 166 1.6E-27 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 MADE_1005365 fa75e14bd25519ecce71cf3bd9df1f71 171 PIRSF PIRSF002094 1 171 2.8E-48 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 MADE_1005365 fa75e14bd25519ecce71cf3bd9df1f71 171 Gene3D G3DSA:3.30.910.20 25 168 6.9E-40 T 13-10-2018 IPR024930 Skp domain superfamily MADE_1005365 fa75e14bd25519ecce71cf3bd9df1f71 171 SMART SM00935 14 168 1.0E-42 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 MADE_1003985 e4d56ad72eef85765d8450a23443d168 328 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 32 319 9.5E-106 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MADE_1003985 e4d56ad72eef85765d8450a23443d168 328 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 4 327 34.815 T 13-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 MADE_1003985 e4d56ad72eef85765d8450a23443d168 328 SUPERFAMILY SSF53659 5 326 1.1E-110 T 13-10-2018 MADE_1003985 e4d56ad72eef85765d8450a23443d168 328 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 324 3.2E-125 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 MADE_1003985 e4d56ad72eef85765d8450a23443d168 328 Gene3D G3DSA:3.40.718.10 1 328 1.3E-123 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 SUPERFAMILY SSF82714 193 274 8.5E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 453 476 2.3E-25 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 478 501 2.3E-25 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 2.3E-25 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.3E-25 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.3E-25 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.3E-25 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 2.3E-25 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:3.30.70.1430 568 672 3.8E-285 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:1.20.1640.10 514 1025 3.8E-285 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 SUPERFAMILY SSF82866 299 504 5.1E-34 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:3.30.70.1440 673 870 3.8E-285 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:3.30.2090.10 189 280 3.8E-285 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:3.30.70.1320 135 333 3.8E-285 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1037 0.0 T 13-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 SUPERFAMILY SSF82693 42 127 1.23E-21 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Pfam PF00873 AcrB/AcrD/AcrF family 5 1029 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 SUPERFAMILY SSF82693 565 666 9.42E-7 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 SUPERFAMILY SSF82693 156 333 2.14E-18 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:3.30.2090.10 724 812 3.8E-285 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:3.30.70.1430 42 820 3.8E-285 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 Gene3D G3DSA:1.20.1640.10 16 513 3.8E-285 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 SUPERFAMILY SSF82866 807 1029 2.62E-52 T 13-10-2018 MADE_1001490 65536c7c0fb1871c3f726c3c21d39aa4 1048 SUPERFAMILY SSF82714 724 807 1.16E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains MADE_1009030 0f170d5954ccf35661870ded0b6d1499 555 SUPERFAMILY SSF50156 147 218 1.52E-6 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1009030 0f170d5954ccf35661870ded0b6d1499 555 Gene3D G3DSA:3.30.750.170 96 446 7.7E-63 T 13-10-2018 MADE_1009030 0f170d5954ccf35661870ded0b6d1499 555 Gene3D G3DSA:2.30.42.10 147 250 7.7E-63 T 13-10-2018 MADE_1009030 0f170d5954ccf35661870ded0b6d1499 555 Pfam PF03572 Peptidase family S41 266 417 1.1E-14 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 MADE_1009030 0f170d5954ccf35661870ded0b6d1499 555 Gene3D G3DSA:3.90.226.10 251 488 7.7E-63 T 13-10-2018 MADE_1009030 0f170d5954ccf35661870ded0b6d1499 555 SUPERFAMILY SSF52096 260 470 1.82E-32 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_000001023180 51f13034f0f15254c80589345ba0591f 237 Pfam PF08388 Group II intron, maturase-specific domain 107 181 1.0E-17 T 13-10-2018 IPR013597 Group II intron, maturase-specific MADE_000001023180 51f13034f0f15254c80589345ba0591f 237 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 4 94 1.8E-19 T 13-10-2018 IPR000477 Reverse transcriptase domain MADE_000001023180 51f13034f0f15254c80589345ba0591f 237 Gene3D G3DSA:3.30.70.270 8 103 5.4E-5 T 13-10-2018 MADE_000001023180 51f13034f0f15254c80589345ba0591f 237 SUPERFAMILY SSF56672 4 181 1.43E-17 T 13-10-2018 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 Pfam PF00672 HAMP domain 306 355 6.0E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 SUPERFAMILY SSF58104 327 636 4.19E-73 T 13-10-2018 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 Pfam PF02743 Cache domain 47 267 7.4E-17 T 13-10-2018 IPR033479 Double Cache domain 1 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 Gene3D G3DSA:3.30.450.20 166 287 9.0E-21 T 13-10-2018 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 Gene3D G3DSA:1.10.287.950 305 636 7.9E-70 T 13-10-2018 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 SMART SM00304 305 359 1.1E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 444 600 1.5E-39 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1002355 e636fd35fc22f619f1263e2897606d1e 636 SMART SM00283 374 635 1.1E-67 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 SMART SM00387 357 468 6.5E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 SMART SM00388 255 313 0.0019 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 SUPERFAMILY SSF47384 238 312 4.51E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 466 1.2E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 SUPERFAMILY SSF55874 302 466 1.05E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 Gene3D G3DSA:1.10.287.130 205 314 3.3E-15 T 13-10-2018 MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 2.4E-6 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 2.4E-6 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1015540 b4d315a7f52c5270b206c2fa92d291fc 468 Gene3D G3DSA:3.30.565.10 321 468 2.9E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001021110 ac580e237aa1073f377c5655da750591 568 Pfam PF00072 Response regulator receiver domain 13 125 9.3E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001021110 ac580e237aa1073f377c5655da750591 568 SUPERFAMILY SSF55874 428 558 6.29E-9 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001021110 ac580e237aa1073f377c5655da750591 568 Gene3D G3DSA:3.40.50.12740 10 175 2.6E-42 T 13-10-2018 MADE_000001021110 ac580e237aa1073f377c5655da750591 568 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 199 390 2.5E-32 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_000001021110 ac580e237aa1073f377c5655da750591 568 SUPERFAMILY SSF52172 11 153 3.84E-40 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001021110 ac580e237aa1073f377c5655da750591 568 SMART SM00331 174 391 2.2E-13 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_000001021110 ac580e237aa1073f377c5655da750591 568 Gene3D G3DSA:3.30.565.10 411 564 7.4E-11 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001021110 ac580e237aa1073f377c5655da750591 568 Gene3D G3DSA:3.60.40.10 176 404 1.2E-35 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_000001021110 ac580e237aa1073f377c5655da750591 568 SUPERFAMILY SSF81606 183 388 5.36E-7 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_000001021110 ac580e237aa1073f377c5655da750591 568 SMART SM00448 11 125 1.8E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1003675 c70dd6106333b04f79c7d832929cdcd4 446 Pfam PF08376 Nitrate and nitrite sensing 46 290 2.5E-44 T 13-10-2018 IPR013587 Nitrate/nitrite sensing protein MADE_1003675 c70dd6106333b04f79c7d832929cdcd4 446 SMART SM01012 381 436 5.0E-17 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 MADE_1003675 c70dd6106333b04f79c7d832929cdcd4 446 Gene3D G3DSA:1.10.10.10 384 443 8.7E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1003675 c70dd6106333b04f79c7d832929cdcd4 446 SUPERFAMILY SSF52172 367 436 1.49E-12 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1003675 c70dd6106333b04f79c7d832929cdcd4 446 Pfam PF03861 ANTAR domain 384 436 2.1E-14 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 Gene3D G3DSA:1.10.287.130 280 380 2.6E-19 T 13-10-2018 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 540 3.6E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 SMART SM00387 430 543 1.1E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 Pfam PF00512 His Kinase A (phospho-acceptor) domain 304 379 1.1E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 SUPERFAMILY SSF47384 298 381 6.28E-6 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 Gene3D G3DSA:3.30.565.10 381 542 7.0E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 1.3E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 499 1.3E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 520 1.3E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 540 1.3E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1001360 9740426f82c1fab49cd75fecf452596a 548 SUPERFAMILY SSF55874 391 542 3.01E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 SUPERFAMILY SSF53474 19 275 1.23E-55 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 TIGRFAM TIGR03611 RutD: pyrimidine utilization protein D 21 275 7.6E-102 T 13-10-2018 IPR019913 Pyrimidine utilisation protein RutD GO:0006212|GO:0016811 MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 Hamap MF_00832 Putative aminoacrylate hydrolase RutD [rutD]. 20 277 45.834 T 13-10-2018 IPR019913 Pyrimidine utilisation protein RutD GO:0006212|GO:0016811 MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 4.9E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 4.9E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 4.9E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 220 234 4.9E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 Gene3D G3DSA:3.40.50.1820 20 277 4.6E-62 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001022895 8d3cd0e830dc24c4f9c4940e095ce80b 278 Pfam PF00561 alpha/beta hydrolase fold 33 258 3.2E-22 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 2 157 1.9E-15 T 13-10-2018 IPR000160 GGDEF domain MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 SUPERFAMILY SSF55073 9 157 2.04E-24 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 Pfam PF00990 Diguanylate cyclase, GGDEF domain 6 152 3.2E-24 T 13-10-2018 IPR000160 GGDEF domain MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 Pfam PF00563 EAL domain 176 408 1.0E-60 T 13-10-2018 IPR001633 EAL domain MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 SUPERFAMILY SSF141868 176 421 1.83E-75 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 SMART SM00267 1 158 1.5E-13 T 13-10-2018 IPR000160 GGDEF domain MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 SMART SM00052 169 414 1.5E-83 T 13-10-2018 IPR001633 EAL domain MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 Gene3D G3DSA:3.20.20.450 170 429 1.7E-80 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007755 66de03e32c4ea87b53100d02e2d677ec 434 Gene3D G3DSA:3.30.70.270 1 169 2.7E-26 T 13-10-2018 MADE_1001160 ddfdfd37fd581477819dadc8cc1d77dc 858 SUPERFAMILY SSF51445 37 333 5.56E-35 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1001160 ddfdfd37fd581477819dadc8cc1d77dc 858 SUPERFAMILY SSF49785 699 832 6.38E-5 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1001160 ddfdfd37fd581477819dadc8cc1d77dc 858 Gene3D G3DSA:3.20.20.80 38 365 6.2E-37 T 13-10-2018 MADE_1000295 366983362e51484caf3da98b6f5527dc 334 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 62 293 6.3E-49 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 MADE_1000295 366983362e51484caf3da98b6f5527dc 334 Gene3D G3DSA:3.40.50.2000 152 334 1.4E-40 T 13-10-2018 MADE_1000295 366983362e51484caf3da98b6f5527dc 334 SUPERFAMILY SSF53756 2 333 2.67E-81 T 13-10-2018 MADE_1000295 366983362e51484caf3da98b6f5527dc 334 Gene3D G3DSA:3.40.50.2000 1 144 4.0E-20 T 13-10-2018 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 Pfam PF01494 FAD binding domain 4 345 7.9E-32 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.7E-20 T 13-10-2018 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.7E-20 T 13-10-2018 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.7E-20 T 13-10-2018 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.7E-20 T 13-10-2018 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 SUPERFAMILY SSF51905 3 382 8.07E-61 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 Gene3D G3DSA:3.30.9.50 79 268 3.9E-116 T 13-10-2018 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 389 1.1E-131 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 Gene3D G3DSA:3.50.50.60 5 337 3.9E-116 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1014480 b8ea8f5d3ad4b1b55b778674c4a569c7 390 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 13-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 MADE_1003315 38659a527e185ab3a1e5bf014bd75fa2 684 Gene3D G3DSA:1.25.20.10 49 413 1.9E-95 T 13-10-2018 MADE_1003315 38659a527e185ab3a1e5bf014bd75fa2 684 Pfam PF01464 Transglycosylase SLT domain 509 615 6.2E-26 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 MADE_1003315 38659a527e185ab3a1e5bf014bd75fa2 684 SUPERFAMILY SSF48435 52 503 1.31E-108 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 MADE_1003315 38659a527e185ab3a1e5bf014bd75fa2 684 Pfam PF14718 Soluble lytic murein transglycosylase L domain 432 498 6.1E-19 T 13-10-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 MADE_1003315 38659a527e185ab3a1e5bf014bd75fa2 684 Gene3D G3DSA:1.10.530.10 499 660 4.1E-44 T 13-10-2018 MADE_1003315 38659a527e185ab3a1e5bf014bd75fa2 684 SUPERFAMILY SSF53955 506 658 7.51E-42 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1007270 17c7d0e6f0273bdcd73c6bbac92f90f0 233 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 186 3.8E-44 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MADE_1007270 17c7d0e6f0273bdcd73c6bbac92f90f0 233 Gene3D G3DSA:3.40.50.300 1 230 9.7E-62 T 13-10-2018 MADE_1007270 17c7d0e6f0273bdcd73c6bbac92f90f0 233 SUPERFAMILY SSF52540 1 222 9.3E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007270 17c7d0e6f0273bdcd73c6bbac92f90f0 233 PIRSF PIRSF006755 1 232 9.4E-63 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MADE_1007270 17c7d0e6f0273bdcd73c6bbac92f90f0 233 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 221 28.908 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 MADE_1007270 17c7d0e6f0273bdcd73c6bbac92f90f0 233 Pfam PF13500 AAA domain 2 220 2.1E-32 T 13-10-2018 MADE_1020220 1d1b781fc45dadfb3dcb25ffcc81226f 455 Pfam PF03109 ABC1 family 127 231 1.5E-23 T 13-10-2018 IPR004147 UbiB domain MADE_1020220 1d1b781fc45dadfb3dcb25ffcc81226f 455 SUPERFAMILY SSF56112 111 340 3.74E-12 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1005845 5829771584f8a4d760c1a617cc0130d1 267 Pfam PF13683 Integrase core domain 199 264 2.6E-23 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1005845 5829771584f8a4d760c1a617cc0130d1 267 Pfam PF13276 HTH-like domain 44 99 1.4E-6 T 13-10-2018 IPR025948 HTH-like domain MADE_1005845 5829771584f8a4d760c1a617cc0130d1 267 SUPERFAMILY SSF53098 108 266 1.52E-36 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1005845 5829771584f8a4d760c1a617cc0130d1 267 Gene3D G3DSA:3.30.420.10 112 242 2.7E-17 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 Gene3D G3DSA:3.40.50.620 6 302 4.2E-98 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 SUPERFAMILY SSF52374 5 310 7.11E-74 T 13-10-2018 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 Gene3D G3DSA:3.40.50.620 80 242 4.2E-98 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 5 292 1.2E-92 T 13-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 8 264 6.7E-40 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 3.3E-13 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 3.3E-13 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 3.3E-13 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 3.3E-13 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1018425 774e6f719d2a895a6010fcab460569fe 327 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 3.3E-13 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 1.5E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 1.5E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 1.5E-9 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 SMART SM00448 1 114 8.6E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 Pfam PF00072 Response regulator receiver domain 3 114 2.2E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 197 1.7E-16 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 SUPERFAMILY SSF46894 139 204 1.02E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 SUPERFAMILY SSF52172 1 128 3.42E-24 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 SMART SM00421 140 197 3.2E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1016420 f870b2838d4821a9ce54c754ed2ec3da 218 Gene3D G3DSA:3.40.50.12740 1 202 2.6E-47 T 13-10-2018 MADE_1007445 f660ec9158da4125ff6851e8339578de 270 SUPERFAMILY SSF53613 3 211 4.21E-37 T 13-10-2018 IPR029056 Ribokinase-like MADE_1007445 f660ec9158da4125ff6851e8339578de 270 Gene3D G3DSA:3.40.1190.20 2 217 5.0E-70 T 13-10-2018 IPR029056 Ribokinase-like MADE_1007445 f660ec9158da4125ff6851e8339578de 270 Gene3D G3DSA:3.40.50.620 231 270 2.2E-7 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1007445 f660ec9158da4125ff6851e8339578de 270 Pfam PF00294 pfkB family carbohydrate kinase 10 210 4.1E-27 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB MADE_1004050 027f1a940956c50c178122f79b94186f 321 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 241 286 9.8E-5 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MADE_1004050 027f1a940956c50c178122f79b94186f 321 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 35 108 1.5E-28 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core MADE_1004050 027f1a940956c50c178122f79b94186f 321 TIGRFAM TIGR00444 mazG: MazG family protein 18 221 6.3E-68 T 13-10-2018 IPR011551 NTP pyrophosphohydrolase MazG MADE_1004050 027f1a940956c50c178122f79b94186f 321 Gene3D G3DSA:1.10.287.1080 7 150 3.2E-47 T 13-10-2018 MADE_1004050 027f1a940956c50c178122f79b94186f 321 SUPERFAMILY SSF101386 170 294 3.09E-20 T 13-10-2018 MADE_1004050 027f1a940956c50c178122f79b94186f 321 Gene3D G3DSA:1.10.287.1080 164 318 2.9E-45 T 13-10-2018 MADE_1004050 027f1a940956c50c178122f79b94186f 321 SUPERFAMILY SSF101386 11 112 1.96E-25 T 13-10-2018 MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 325 2.9E-14 T 13-10-2018 IPR010918 PurM-like, C-terminal domain MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 20 350 5.9E-109 T 13-10-2018 IPR011854 Carbamoyl dehydratase HypE MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 SUPERFAMILY SSF55326 19 164 9.59E-30 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 Gene3D G3DSA:3.30.1330.10 21 165 1.0E-43 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 Pfam PF00586 AIR synthase related protein, N-terminal domain 52 161 1.7E-16 T 13-10-2018 IPR016188 PurM-like, N-terminal domain MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 PIRSF PIRSF005644 16 350 4.7E-103 T 13-10-2018 IPR011854 Carbamoyl dehydratase HypE MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 Gene3D G3DSA:3.90.650.10 168 350 3.2E-43 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1001710 c68af6ca6b21592a14d3abb038198781 350 SUPERFAMILY SSF56042 172 344 2.39E-32 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 SUPERFAMILY SSF160387 88 208 5.23E-41 T 13-10-2018 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 Gene3D G3DSA:2.40.10.490 9 210 2.9E-81 T 13-10-2018 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 SUPERFAMILY SSF46785 29 87 3.9E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 PIRSF PIRSF001458 5 210 3.3E-85 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 PRINTS PR01699 Organomercurial lyase signature 170 185 3.6E-31 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 PRINTS PR01699 Organomercurial lyase signature 82 96 3.6E-31 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 PRINTS PR01699 Organomercurial lyase signature 124 135 3.6E-31 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 PRINTS PR01699 Organomercurial lyase signature 41 54 3.6E-31 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 PRINTS PR01699 Organomercurial lyase signature 99 108 3.6E-31 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 Pfam PF12324 Helix-turn-helix domain of alkylmercury lyase 12 80 5.3E-20 T 13-10-2018 IPR024259 Alkylmercury lyase, helix-turn-helix domain MADE_1005535 c58246c7cee700aba73f7b24d5ed24c5 210 Pfam PF03243 Alkylmercury lyase 83 203 6.3E-39 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1002100 769181a0640cd015f851000005abfc92 405 Gene3D G3DSA:1.20.1250.20 203 405 1.4E-32 T 13-10-2018 MADE_1002100 769181a0640cd015f851000005abfc92 405 Gene3D G3DSA:1.20.1250.20 3 195 1.6E-16 T 13-10-2018 MADE_1002100 769181a0640cd015f851000005abfc92 405 Pfam PF03825 Nucleoside H+ symporter 2 399 1.3E-123 T 13-10-2018 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 MADE_1002100 769181a0640cd015f851000005abfc92 405 SUPERFAMILY SSF103473 3 400 8.24E-39 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 PRINTS PR01755 Bacterial translocase SecF protein signature 574 589 1.8E-25 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 PRINTS PR01755 Bacterial translocase SecF protein signature 740 758 1.8E-25 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 PRINTS PR01755 Bacterial translocase SecF protein signature 692 706 1.8E-25 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 PRINTS PR01755 Bacterial translocase SecF protein signature 772 787 1.8E-25 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Gene3D G3DSA:3.30.1360.200 215 341 1.9E-56 T 13-10-2018 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 46 510 1.2E-130 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Gene3D G3DSA:1.20.1640.10 668 855 2.1E-18 T 13-10-2018 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 SUPERFAMILY SSF82866 646 836 6.67E-40 T 13-10-2018 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 575 823 2.0E-65 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 547 835 25.111 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 273 503 1.3E-75 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Pfam PF02355 Protein export membrane protein 344 511 7.7E-19 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Pfam PF02355 Protein export membrane protein 650 832 6.1E-54 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 522 39.792 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Gene3D G3DSA:1.20.1640.10 344 530 1.0E-19 T 13-10-2018 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Gene3D G3DSA:3.30.70.3400 158 343 1.9E-56 T 13-10-2018 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 SUPERFAMILY SSF82866 256 517 1.7E-40 T 13-10-2018 MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Pfam PF07549 SecD/SecF GG Motif 40 64 9.9E-5 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MADE_1004295 2eaab869befe8cb34d40afbdbf1a2534 858 Pfam PF07549 SecD/SecF GG Motif 570 591 1.7E-6 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 Pfam PF00347 Ribosomal protein L6 91 164 1.0E-21 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 Pfam PF00347 Ribosomal protein L6 13 82 6.9E-17 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 PIRSF PIRSF002162 1 177 4.4E-44 T 13-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 SUPERFAMILY SSF56053 83 177 6.91E-38 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 SUPERFAMILY SSF56053 1 82 4.0E-21 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 Gene3D G3DSA:3.90.930.12 83 177 6.3E-41 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 13-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 Gene3D G3DSA:3.90.930.12 1 82 2.7E-26 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.2E-33 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.2E-33 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.2E-33 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 5.6E-74 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MADE_1013985 7a4f70b25600f7d575c2b2f2b0869900 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.954 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 MADE_1009815 9b1b17a060bd0043cf6915839a7d1751 331 SUPERFAMILY SSF52821 94 241 1.51E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1009815 9b1b17a060bd0043cf6915839a7d1751 331 Gene3D G3DSA:3.30.70.100 1 96 2.3E-34 T 13-10-2018 MADE_1009815 9b1b17a060bd0043cf6915839a7d1751 331 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 254 45.625 T 13-10-2018 IPR020936 Uncharacterised protein family UPF0176 MADE_1009815 9b1b17a060bd0043cf6915839a7d1751 331 Pfam PF00581 Rhodanese-like domain 115 209 1.8E-7 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1009815 9b1b17a060bd0043cf6915839a7d1751 331 SMART SM00450 113 214 1.9E-20 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1009815 9b1b17a060bd0043cf6915839a7d1751 331 Gene3D G3DSA:3.40.250.10 97 250 4.6E-51 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1014390 6a4993676c2347cced5e1f42caddbcc5 222 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 1 221 9.0E-50 T 13-10-2018 IPR010179 CRISPR-associated protein Cse3 MADE_1014390 6a4993676c2347cced5e1f42caddbcc5 222 SUPERFAMILY SSF117987 84 221 3.4E-27 T 13-10-2018 MADE_1014390 6a4993676c2347cced5e1f42caddbcc5 222 SUPERFAMILY SSF117987 1 70 3.66E-8 T 13-10-2018 MADE_1014390 6a4993676c2347cced5e1f42caddbcc5 222 Pfam PF08798 CRISPR associated protein 1 221 1.2E-46 T 13-10-2018 IPR010179 CRISPR-associated protein Cse3 MADE_1014390 6a4993676c2347cced5e1f42caddbcc5 222 Gene3D G3DSA:3.30.70.1210 84 221 6.1E-27 T 13-10-2018 MADE_1014390 6a4993676c2347cced5e1f42caddbcc5 222 Gene3D G3DSA:3.30.70.1200 1 82 1.7E-5 T 13-10-2018 MADE_1014390 6a4993676c2347cced5e1f42caddbcc5 222 SMART SM01101 1 221 5.9E-74 T 13-10-2018 IPR010179 CRISPR-associated protein Cse3 MADE_1000465 665f09253c19056bf8d50e0be2c44871 131 SUPERFAMILY SSF52821 8 129 5.63E-27 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1000465 665f09253c19056bf8d50e0be2c44871 131 SMART SM00450 18 128 4.0E-20 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1000465 665f09253c19056bf8d50e0be2c44871 131 Gene3D G3DSA:3.40.250.10 1 131 2.0E-29 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1000465 665f09253c19056bf8d50e0be2c44871 131 Pfam PF00581 Rhodanese-like domain 21 124 1.4E-17 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 13-10-2018 IPR033135 ClpP, histidine active site MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 Pfam PF00574 Clp protease 22 201 8.7E-89 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 4.7E-54 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 4.7E-54 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 4.7E-54 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 PRINTS PR00127 Clp protease catalytic subunit P signature 177 196 4.7E-54 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 4.7E-54 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 SUPERFAMILY SSF52096 19 203 1.49E-74 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 13-10-2018 IPR018215 ClpP, Ser active site MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 Gene3D G3DSA:3.90.226.10 6 207 4.2E-84 T 13-10-2018 MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 11 200 2.1E-106 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MADE_1012755 a6750dce692f1455f75438fe392ca3ca 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 202 44.323 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 Pfam PF13411 MerR HTH family regulatory protein 4 70 1.9E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.0E-14 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.0E-14 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.0E-14 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 SUPERFAMILY SSF46955 4 126 4.76E-29 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 Gene3D G3DSA:1.10.1660.10 1 125 9.2E-31 T 13-10-2018 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 5 126 4.1E-51 T 13-10-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 SMART SM00422 4 72 2.5E-19 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1005560 400d6af23144f97e1da6a768c6f77e29 128 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_000001023640 433b4a0d96402ba004c62e4ad1c77c3d 124 PIRSF PIRSF016789 6 124 1.3E-32 T 13-10-2018 IPR007401 Protein of unknown function DUF454 MADE_000001023640 433b4a0d96402ba004c62e4ad1c77c3d 124 Pfam PF04304 Protein of unknown function (DUF454) 7 121 1.3E-33 T 13-10-2018 IPR007401 Protein of unknown function DUF454 MADE_1007735 30b02168854680c884bde60eed7cd3e0 315 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 35 169 7.8E-60 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MADE_1007735 30b02168854680c884bde60eed7cd3e0 315 SUPERFAMILY SSF52540 5 279 2.47E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007735 30b02168854680c884bde60eed7cd3e0 315 PIRSF PIRSF002849 1 313 2.0E-117 T 13-10-2018 MADE_1007735 30b02168854680c884bde60eed7cd3e0 315 Gene3D G3DSA:1.10.8.300 197 308 3.0E-25 T 13-10-2018 MADE_1007735 30b02168854680c884bde60eed7cd3e0 315 Gene3D G3DSA:3.40.50.300 16 185 1.2E-40 T 13-10-2018 MADE_1010130 cda7aeca7e9cfb0c2e40a9e9f5220f1f 222 Pfam PF17516 ProQ C-terminal domain 167 215 4.2E-23 T 13-10-2018 IPR035236 RNA chaperone ProQ, C-terminal MADE_1010130 cda7aeca7e9cfb0c2e40a9e9f5220f1f 222 Pfam PF04352 ProQ/FINO family 8 115 3.3E-41 T 13-10-2018 IPR016103 ProQ/FinO domain MADE_1010130 cda7aeca7e9cfb0c2e40a9e9f5220f1f 222 SUPERFAMILY SSF48657 4 117 4.97E-36 T 13-10-2018 IPR036442 ProQ/FinO domain superfamily MADE_1010130 cda7aeca7e9cfb0c2e40a9e9f5220f1f 222 Gene3D G3DSA:1.10.1710.10 2 121 6.7E-21 T 13-10-2018 IPR036442 ProQ/FinO domain superfamily MADE_1010130 cda7aeca7e9cfb0c2e40a9e9f5220f1f 222 Hamap MF_00749 RNA chaperone ProQ [proQ]. 2 217 27.315 T 13-10-2018 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 MADE_1010130 cda7aeca7e9cfb0c2e40a9e9f5220f1f 222 SMART SM00945 5 119 2.5E-57 T 13-10-2018 IPR016103 ProQ/FinO domain MADE_000001020865 e335c87c77cf74c76a2162e8fc09a343 97 Gene3D G3DSA:1.20.1600.10 1 90 9.6E-14 T 13-10-2018 MADE_000001020865 e335c87c77cf74c76a2162e8fc09a343 97 SUPERFAMILY SSF56954 2 88 4.19E-14 T 13-10-2018 MADE_000001020865 e335c87c77cf74c76a2162e8fc09a343 97 Pfam PF02321 Outer membrane efflux protein 2 88 2.4E-8 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1011970 34be0df5e31797ca30d0af9d505d8d54 741 SUPERFAMILY SSF51905 272 736 2.07E-16 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1011970 34be0df5e31797ca30d0af9d505d8d54 741 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 117 241 2.0E-42 T 13-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 MADE_1011970 34be0df5e31797ca30d0af9d505d8d54 741 Gene3D G3DSA:3.50.50.60 527 741 4.2E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1011970 34be0df5e31797ca30d0af9d505d8d54 741 Gene3D G3DSA:3.50.50.60 257 379 1.9E-25 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1011970 34be0df5e31797ca30d0af9d505d8d54 741 Pfam PF01266 FAD dependent oxidoreductase 272 708 2.6E-26 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 MADE_1011970 34be0df5e31797ca30d0af9d505d8d54 741 Gene3D G3DSA:3.40.50.150 6 251 5.2E-99 T 13-10-2018 MADE_1011970 34be0df5e31797ca30d0af9d505d8d54 741 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 4 734 24.576 T 13-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 MADE_1015185 d062c1a1bc3af778385d47d9812d6ab0 111 Hamap MF_00910 Cell division protein FtsL [ftsL]. 25 108 15.648 T 13-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MADE_1015185 d062c1a1bc3af778385d47d9812d6ab0 111 Pfam PF04999 Cell division protein FtsL 18 109 3.0E-29 T 13-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MADE_1015185 d062c1a1bc3af778385d47d9812d6ab0 111 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 26 109 7.1E-19 T 13-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 MADE_1003335 491a3694cc4104ce969bfb864f3dee77 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.1E-44 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003335 491a3694cc4104ce969bfb864f3dee77 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.003 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003335 491a3694cc4104ce969bfb864f3dee77 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.7E-39 T 13-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003335 491a3694cc4104ce969bfb864f3dee77 103 SUPERFAMILY SSF141091 1 102 1.44E-38 T 13-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1003335 491a3694cc4104ce969bfb864f3dee77 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 13-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Hamap MF_02092 Quinone-dependent D-lactate dehydrogenase [dld]. 4 563 56.683 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Pfam PF09330 D-lactate dehydrogenase, membrane binding 271 561 1.7E-132 T 13-10-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 SUPERFAMILY SSF56176 5 266 2.02E-65 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Gene3D G3DSA:3.30.43.10 2 95 9.6E-12 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Gene3D G3DSA:3.30.70.610 368 429 1.7E-13 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Gene3D G3DSA:3.30.70.610 262 337 2.1E-17 T 13-10-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Gene3D G3DSA:3.30.1370.20 430 514 2.1E-38 T 13-10-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 SUPERFAMILY SSF55103 268 560 9.81E-105 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 PIRSF PIRSF000101 1 565 4.6E-265 T 13-10-2018 IPR012256 D-lactate dehydrogenase GO:0005887|GO:0016901|GO:0019516|GO:0022904|GO:0050660 KEGG: 00620+1.1.5.12|MetaCyc: PWY-5386|MetaCyc: PWY-7425 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Pfam PF01565 FAD binding domain 41 179 4.6E-8 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MADE_000001022270 a7b2bd4dffe9d3370d20ef9c721feb1b 567 Gene3D G3DSA:3.30.465.10 100 261 8.2E-70 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1009200 548b5854bd94a1188ab7bfb61b6a00d5 184 Pfam PF14279 HNH endonuclease 88 142 7.6E-21 T 13-10-2018 IPR029471 HNH endonuclease 5 MADE_1009200 548b5854bd94a1188ab7bfb61b6a00d5 184 SMART SM00507 75 128 2.9E-13 T 13-10-2018 IPR003615 HNH nuclease MADE_1009200 548b5854bd94a1188ab7bfb61b6a00d5 184 Gene3D G3DSA:3.30.40.60 63 157 2.7E-24 T 13-10-2018 MADE_1000765 e82e34a20ac30e100b44eee07a769026 90 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.7E-26 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1000765 e82e34a20ac30e100b44eee07a769026 90 SMART SM01409 8 61 4.3E-16 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MADE_1000765 e82e34a20ac30e100b44eee07a769026 90 SUPERFAMILY SSF63562 1 78 4.01E-25 T 13-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MADE_1000765 e82e34a20ac30e100b44eee07a769026 90 Gene3D G3DSA:3.90.940.10 1 90 6.9E-28 T 13-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MADE_1000765 e82e34a20ac30e100b44eee07a769026 90 Pfam PF01192 RNA polymerase Rpb6 10 60 2.6E-16 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 MADE_1000765 e82e34a20ac30e100b44eee07a769026 90 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.4 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 MADE_1001590 a18ce0680e3450758bcf12a13a3496ad 232 Pfam PF07786 Protein of unknown function (DUF1624) 4 216 5.4E-52 T 13-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 169 187 - T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 Pfam PF00557 Metallopeptidase family M24 12 243 5.8E-57 T 13-10-2018 IPR000994 Peptidase M24 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 Gene3D G3DSA:3.90.230.10 2 261 5.4E-116 T 13-10-2018 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 SUPERFAMILY SSF55920 4 255 2.88E-94 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 Hamap MF_01974 Methionine aminopeptidase [map]. 3 252 42.36 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 251 4.1E-100 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 2.0E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 206 2.0E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 2.0E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_000001020840 764e2efcab32e57aac7d19a8814d7b89 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 2.0E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 MADE_1020095 235d1f8bcc46a5713023805c0dd10a59 195 Gene3D G3DSA:2.60.370.10 52 184 6.6E-42 T 13-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020095 235d1f8bcc46a5713023805c0dd10a59 195 SUPERFAMILY SSF110111 52 174 3.66E-43 T 13-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020095 235d1f8bcc46a5713023805c0dd10a59 195 PIRSF PIRSF005413 1 186 2.4E-64 T 13-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020095 235d1f8bcc46a5713023805c0dd10a59 195 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 28 171 2.1E-49 T 13-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 17 388 4.2E-151 T 13-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 22 41 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 108 116 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 Gene3D G3DSA:3.90.550.10 3 291 1.7E-85 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 207 217 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 Gene3D G3DSA:2.160.10.10 292 418 1.1E-36 T 13-10-2018 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 Pfam PF00483 Nucleotidyl transferase 18 280 5.3E-64 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 SUPERFAMILY SSF53448 14 383 2.58E-75 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 13 415 49.058 T 13-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 MADE_1008400 97a7472f75cd8301e11231aa8e42fd32 431 SUPERFAMILY SSF51161 302 412 6.79E-17 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 SUPERFAMILY SSF55681 8 290 1.44E-137 T 13-10-2018 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 Gene3D G3DSA:3.30.930.10 1 214 2.7E-111 T 13-10-2018 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 290 1.5E-152 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 8.8E-70 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 8.8E-70 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 8.8E-70 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 8.8E-70 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 8.8E-70 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 251 267 8.8E-70 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 291 61.33 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 Gene3D G3DSA:1.20.58.180 215 296 9.4E-36 T 13-10-2018 MADE_1000040 678a2777c76a2f3be9779e82648b0602 301 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 299 9.4E-172 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1012955 3285557aefb3143a60723a05443571c3 614 PRINTS PR00702 Acriflavin resistance protein family signature 577 600 8.8E-8 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1012955 3285557aefb3143a60723a05443571c3 614 PRINTS PR00702 Acriflavin resistance protein family signature 502 526 8.8E-8 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1012955 3285557aefb3143a60723a05443571c3 614 PRINTS PR00702 Acriflavin resistance protein family signature 448 471 8.8E-8 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 MADE_1012955 3285557aefb3143a60723a05443571c3 614 Pfam PF02355 Protein export membrane protein 432 601 9.1E-21 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MADE_1012955 3285557aefb3143a60723a05443571c3 614 Pfam PF07549 SecD/SecF GG Motif 116 140 1.2E-6 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MADE_1012955 3285557aefb3143a60723a05443571c3 614 Gene3D G3DSA:1.20.1640.10 453 600 3.0E-8 T 13-10-2018 MADE_1012955 3285557aefb3143a60723a05443571c3 614 Gene3D G3DSA:3.30.1360.200 277 430 1.1E-50 T 13-10-2018 MADE_1012955 3285557aefb3143a60723a05443571c3 614 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 613 47.439 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MADE_1012955 3285557aefb3143a60723a05443571c3 614 SUPERFAMILY SSF82866 409 603 8.11E-46 T 13-10-2018 MADE_1012955 3285557aefb3143a60723a05443571c3 614 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 600 1.0E-150 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 MADE_1012955 3285557aefb3143a60723a05443571c3 614 Pfam PF13721 SecD export protein N-terminal TM region 2 103 7.2E-32 T 13-10-2018 IPR027398 SecD export protein N-terminal TM domain MADE_1012955 3285557aefb3143a60723a05443571c3 614 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 344 593 1.9E-83 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1012955 3285557aefb3143a60723a05443571c3 614 Gene3D G3DSA:3.30.70.3400 217 436 1.1E-50 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 Pfam PF00117 Glutamine amidotransferase class-I 12 200 1.6E-39 T 13-10-2018 IPR017926 Glutamine amidotransferase MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 213 525 1.5E-154 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 SUPERFAMILY SSF52317 9 208 1.45E-55 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 205 2.1E-82 T 13-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 Gene3D G3DSA:3.30.300.10 406 525 2.9E-50 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 Gene3D G3DSA:3.40.50.880 9 206 3.9E-55 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 Gene3D G3DSA:3.40.50.620 209 405 3.4E-77 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 56.583 T 13-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 4.7E-5 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 4.7E-5 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 4.7E-5 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.6E-7 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 1.6E-7 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.6E-7 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 SUPERFAMILY SSF52402 197 420 1.79E-59 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 SUPERFAMILY SSF54810 405 525 2.22E-50 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 Pfam PF00958 GMP synthase C terminal domain 433 524 4.2E-43 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 2.2E-6 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 2.2E-6 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 2.2E-6 T 13-10-2018 MADE_1005260 284fa8654d895ddcf516a24f2c1261c1 525 Pfam PF02540 NAD synthase 215 258 5.0E-7 T 13-10-2018 IPR022310 NAD/GMP synthase MADE_1003825 a65e85b6be09e78d31c2f44968a075f5 278 SUPERFAMILY SSF109604 11 261 6.28E-50 T 13-10-2018 MADE_1003825 a65e85b6be09e78d31c2f44968a075f5 278 Gene3D G3DSA:1.10.3210.10 1 277 1.1E-57 T 13-10-2018 MADE_1003825 a65e85b6be09e78d31c2f44968a075f5 278 Pfam PF08668 HDOD domain 22 211 1.4E-35 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 Gene3D G3DSA:3.40.50.460 170 292 2.5E-93 T 13-10-2018 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 276 298 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 247 259 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 60 73 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 188 204 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 168 186 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 122 138 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 35 54 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 150 167 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 206 223 4.7E-67 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 SUPERFAMILY SSF53784 30 346 3.66E-100 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 Pfam PF00365 Phosphofructokinase 32 311 4.2E-93 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 Gene3D G3DSA:3.40.50.450 33 336 2.5E-93 T 13-10-2018 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 ProSitePatterns PS00433 Phosphofructokinase signature. 280 298 - T 13-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 MADE_1009720 efcb7b280c0153a9f0decb5e65926739 364 PIRSF PIRSF000532 29 361 1.7E-102 T 13-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 MADE_1014305 abcf8a7d788497e7c33c3b4de9370381 276 Pfam PF00005 ABC transporter 47 202 1.4E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1014305 abcf8a7d788497e7c33c3b4de9370381 276 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 31 272 1.8E-113 T 13-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD MADE_1014305 abcf8a7d788497e7c33c3b4de9370381 276 SUPERFAMILY SSF52540 31 273 7.5E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014305 abcf8a7d788497e7c33c3b4de9370381 276 Gene3D G3DSA:3.40.50.300 30 274 2.5E-52 T 13-10-2018 MADE_1014305 abcf8a7d788497e7c33c3b4de9370381 276 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 250 271 3.8E-8 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal MADE_000001021455 41d74e65abcc8bdc0a8b4f8342fdc383 324 SMART SM01321 13 188 8.5E-4 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 MADE_000001021455 41d74e65abcc8bdc0a8b4f8342fdc383 324 SUPERFAMILY SSF143422 16 193 7.32E-19 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 Gene3D G3DSA:1.10.287.80 6 282 1.1E-109 T 13-10-2018 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 Pfam PF00231 ATP synthase 5 285 3.8E-96 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 286 1.7E-110 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 Gene3D G3DSA:3.40.1380.10 61 205 1.1E-109 T 13-10-2018 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 13-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 4.8E-38 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 4.8E-38 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 4.8E-38 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 4.8E-38 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 36.657 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020455 0d97964ad0e490052a4cb1d9b36b005b 286 SUPERFAMILY SSF52943 2 286 4.81E-97 T 13-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001023615 698be161a2c11092bc8b100792862a51 145 Gene3D G3DSA:2.60.120.460 5 142 4.2E-39 T 13-10-2018 IPR035917 YjbQ-like superfamily MADE_000001023615 698be161a2c11092bc8b100792862a51 145 Pfam PF01894 Uncharacterised protein family UPF0047 23 138 2.5E-36 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 MADE_000001023615 698be161a2c11092bc8b100792862a51 145 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 18 142 2.4E-42 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 MADE_000001023615 698be161a2c11092bc8b100792862a51 145 PIRSF PIRSF004681 3 143 3.0E-41 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 MADE_000001023615 698be161a2c11092bc8b100792862a51 145 SUPERFAMILY SSF111038 6 142 7.46E-45 T 13-10-2018 IPR035917 YjbQ-like superfamily MADE_1014035 decb54f6653ed4b2b9310289c1cfff9d 130 Pfam PF09722 Protein of unknown function (DUF2384) 76 128 7.7E-6 T 13-10-2018 IPR024467 Domain of unknown function DUF2384 MADE_1014035 decb54f6653ed4b2b9310289c1cfff9d 130 ProDom PD080812 PLASMID Y4OB BMEII097 AGR_L_107P MLL2216 BMEII0977 ATU4831 16 107 6.0E-14 T 13-10-2018 IPR020358 Uncharacterised protein family Y4oB MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 Gene3D G3DSA:1.10.3860.10 8 404 1.4E-71 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 6 406 35.601 T 13-10-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 9.0E-17 T 13-10-2018 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 9.0E-17 T 13-10-2018 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 9.0E-17 T 13-10-2018 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 9.0E-17 T 13-10-2018 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 PRINTS PR00173 Glutamate-aspartate symporter signature 223 242 9.0E-17 T 13-10-2018 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 PRINTS PR00173 Glutamate-aspartate symporter signature 352 372 9.0E-17 T 13-10-2018 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 SUPERFAMILY SSF118215 18 401 1.24E-95 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MADE_1004485 33f6267506cd6263c45aa9f515ab10f4 406 Pfam PF00375 Sodium:dicarboxylate symporter family 18 398 4.7E-67 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MADE_1004870 57cb942498cb1c8db237cddf546b578b 104 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 41 102 8.6E-21 T 13-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain MADE_1004870 57cb942498cb1c8db237cddf546b578b 104 SUPERFAMILY SSF47781 25 102 7.89E-26 T 13-10-2018 IPR010994 RuvA domain 2-like MADE_1004870 57cb942498cb1c8db237cddf546b578b 104 Pfam PF12836 Helix-hairpin-helix motif 39 101 4.0E-22 T 13-10-2018 MADE_1004870 57cb942498cb1c8db237cddf546b578b 104 SMART SM00278 81 100 10.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MADE_1004870 57cb942498cb1c8db237cddf546b578b 104 SMART SM00278 51 70 0.39 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 MADE_1004870 57cb942498cb1c8db237cddf546b578b 104 Gene3D G3DSA:1.10.150.280 32 104 1.3E-22 T 13-10-2018 MADE_1015020 ab5c475c33bfc650f8b0711e6cb294ef 297 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 22 135 7.8E-34 T 13-10-2018 IPR010627 Peptidase A24A, N-terminal MADE_1015020 ab5c475c33bfc650f8b0711e6cb294ef 297 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 222 233 1.6E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MADE_1015020 ab5c475c33bfc650f8b0711e6cb294ef 297 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 154 171 1.6E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MADE_1015020 ab5c475c33bfc650f8b0711e6cb294ef 297 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 234 249 1.6E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MADE_1015020 ab5c475c33bfc650f8b0711e6cb294ef 297 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 211 221 1.6E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial MADE_1015020 ab5c475c33bfc650f8b0711e6cb294ef 297 Pfam PF01478 Type IV leader peptidase family 146 254 1.4E-24 T 13-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 MADE_1007785 538d223e2357a0f7aa56bddc9f1c2684 232 Gene3D G3DSA:3.30.1380.10 4 195 1.6E-33 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MADE_1007785 538d223e2357a0f7aa56bddc9f1c2684 232 SUPERFAMILY SSF55166 15 178 4.71E-20 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MADE_1007785 538d223e2357a0f7aa56bddc9f1c2684 232 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 24 179 3.8E-34 T 13-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 MADE_000001021145 7cd6c6d45c73f57c4dba527ef789ce2a 60 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 59 3.1E-12 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_000001021145 7cd6c6d45c73f57c4dba527ef789ce2a 60 SUPERFAMILY SSF64518 1 60 8.11E-18 T 13-10-2018 MADE_000001021145 7cd6c6d45c73f57c4dba527ef789ce2a 60 Gene3D G3DSA:1.20.58.1830 5 31 3.5E-16 T 13-10-2018 MADE_000001021145 7cd6c6d45c73f57c4dba527ef789ce2a 60 Gene3D G3DSA:1.20.1330.10 43 60 3.5E-16 T 13-10-2018 MADE_1014155 2f43b12ed1bfe2f9a9c646ac8ffb6c92 183 Pfam PF01965 DJ-1/PfpI family 10 180 1.1E-41 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 MADE_1014155 2f43b12ed1bfe2f9a9c646ac8ffb6c92 183 Gene3D G3DSA:3.40.50.880 1 183 5.8E-48 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1014155 2f43b12ed1bfe2f9a9c646ac8ffb6c92 183 SUPERFAMILY SSF52317 9 181 2.37E-41 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1014155 2f43b12ed1bfe2f9a9c646ac8ffb6c92 183 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 11 182 6.3E-44 T 13-10-2018 IPR006286 Deglycase PfpI MADE_1011635 88dd924cc588e6f83ff83bf1748c304a 379 Gene3D G3DSA:2.60.40.3120 1 112 8.7E-44 T 13-10-2018 MADE_1011635 88dd924cc588e6f83ff83bf1748c304a 379 SMART SM00631 112 354 3.2E-4 T 13-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MADE_1011635 88dd924cc588e6f83ff83bf1748c304a 379 Pfam PF00246 Zinc carboxypeptidase 129 341 8.6E-23 T 13-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 MADE_1011635 88dd924cc588e6f83ff83bf1748c304a 379 SUPERFAMILY SSF53187 105 373 2.48E-59 T 13-10-2018 MADE_1011635 88dd924cc588e6f83ff83bf1748c304a 379 Gene3D G3DSA:3.40.630.10 113 376 1.6E-69 T 13-10-2018 MADE_1004640 9e53f39b0c11742d0eef53e880868600 591 Gene3D G3DSA:2.60.40.10 163 249 2.6E-13 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1004640 9e53f39b0c11742d0eef53e880868600 591 Pfam PF07603 Protein of unknown function (DUF1566) 432 588 3.3E-29 T 13-10-2018 IPR011460 Protein of unknown function DUF1566 MADE_1004640 9e53f39b0c11742d0eef53e880868600 591 Gene3D G3DSA:2.60.40.10 253 358 8.3E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1004640 9e53f39b0c11742d0eef53e880868600 591 Gene3D G3DSA:2.60.40.10 52 149 6.0E-9 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1015150 6b8a3af6363e3d479761bf90c4c700a7 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 360 34.529 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015150 6b8a3af6363e3d479761bf90c4c700a7 364 Gene3D G3DSA:3.40.50.2000 166 344 1.5E-108 T 13-10-2018 MADE_1015150 6b8a3af6363e3d479761bf90c4c700a7 364 SUPERFAMILY SSF53756 3 360 1.4E-112 T 13-10-2018 MADE_1015150 6b8a3af6363e3d479761bf90c4c700a7 364 Gene3D G3DSA:3.40.50.2000 6 350 1.5E-108 T 13-10-2018 MADE_1015150 6b8a3af6363e3d479761bf90c4c700a7 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 336 8.7E-37 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 MADE_1015150 6b8a3af6363e3d479761bf90c4c700a7 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 142 1.4E-44 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1015150 6b8a3af6363e3d479761bf90c4c700a7 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 354 4.0E-99 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 MADE_1014290 941832959580220a3be645a00d9d9f1f 100 Pfam PF00547 Urease, gamma subunit 1 99 2.5E-46 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014290 941832959580220a3be645a00d9d9f1f 100 PIRSF PIRSF001223 1 100 6.3E-49 T 13-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014290 941832959580220a3be645a00d9d9f1f 100 Gene3D G3DSA:3.30.280.10 1 100 3.2E-47 T 13-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014290 941832959580220a3be645a00d9d9f1f 100 SUPERFAMILY SSF54111 1 99 6.41E-45 T 13-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014290 941832959580220a3be645a00d9d9f1f 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.56 T 13-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014290 941832959580220a3be645a00d9d9f1f 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.5E-49 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014290 941832959580220a3be645a00d9d9f1f 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 9.0E-39 T 13-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 Pfam PF00920 Dehydratase family 34 606 2.5E-217 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 SUPERFAMILY SSF52016 421 611 1.49E-58 T 13-10-2018 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 609 44.885 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 SUPERFAMILY SSF143975 3 420 1.44E-135 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 609 4.1E-256 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 MADE_1020125 f7f9e23114880336294f44227604ab9a 616 Gene3D G3DSA:3.50.30.80 421 572 8.7E-52 T 13-10-2018 MADE_000001021765 b1178163963dfb4db3a51785ff04319f 204 Pfam PF07681 DoxX 20 104 5.1E-19 T 13-10-2018 IPR032808 DoxX family MADE_1016245 73dbce819976071396175146ec271bca 276 SMART SM00382 44 237 1.8E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1016245 73dbce819976071396175146ec271bca 276 Gene3D G3DSA:3.40.50.300 12 275 3.8E-58 T 13-10-2018 MADE_1016245 73dbce819976071396175146ec271bca 276 SUPERFAMILY SSF52540 17 251 9.57E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1016245 73dbce819976071396175146ec271bca 276 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1016245 73dbce819976071396175146ec271bca 276 Pfam PF00005 ABC transporter 35 190 1.2E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1013680 c79fd6603a84b8dc5e04fb3bb02bff44 200 SUPERFAMILY SSF52218 1 197 2.74E-50 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1013680 c79fd6603a84b8dc5e04fb3bb02bff44 200 Gene3D G3DSA:3.40.50.360 1 199 4.7E-54 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1013680 c79fd6603a84b8dc5e04fb3bb02bff44 200 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 198 27.912 T 13-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 MADE_1013680 c79fd6603a84b8dc5e04fb3bb02bff44 200 Pfam PF02525 Flavodoxin-like fold 2 195 4.2E-42 T 13-10-2018 IPR003680 Flavodoxin-like fold MADE_1004740 68caee46a9682cbcd67d752c0c1ed1f2 273 Pfam PF00005 ABC transporter 38 180 1.2E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004740 68caee46a9682cbcd67d752c0c1ed1f2 273 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1004740 68caee46a9682cbcd67d752c0c1ed1f2 273 SMART SM00382 46 229 7.2E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004740 68caee46a9682cbcd67d752c0c1ed1f2 273 SUPERFAMILY SSF52540 33 237 5.11E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004740 68caee46a9682cbcd67d752c0c1ed1f2 273 Gene3D G3DSA:3.40.50.300 13 252 3.4E-64 T 13-10-2018 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.5E-12 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 Gene3D G3DSA:3.40.190.10 96 260 1.0E-42 T 13-10-2018 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.8E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.8E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.8E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 SUPERFAMILY SSF46785 2 84 3.54E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 SUPERFAMILY SSF53850 84 266 7.29E-27 T 13-10-2018 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 Gene3D G3DSA:1.10.10.10 4 89 1.9E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 Gene3D G3DSA:3.40.190.10 163 254 1.0E-42 T 13-10-2018 MADE_1014450 44491fec0462765ec10ec5fb4b55bedd 282 Pfam PF03466 LysR substrate binding domain 89 240 5.5E-26 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1012305 b3d6045906288b3fbf5e37158e6e5b53 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 209 218 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MADE_1012305 b3d6045906288b3fbf5e37158e6e5b53 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 353 52.732 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MADE_1012305 b3d6045906288b3fbf5e37158e6e5b53 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 351 2.8E-107 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 MADE_1012305 b3d6045906288b3fbf5e37158e6e5b53 359 Gene3D G3DSA:3.40.640.10 53 256 1.4E-122 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1012305 b3d6045906288b3fbf5e37158e6e5b53 359 Gene3D G3DSA:3.90.1150.10 8 345 1.4E-122 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1012305 b3d6045906288b3fbf5e37158e6e5b53 359 Pfam PF00155 Aminotransferase class I and II 46 347 4.3E-54 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1012305 b3d6045906288b3fbf5e37158e6e5b53 359 SUPERFAMILY SSF53383 16 352 9.04E-68 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SUPERFAMILY SSF49299 5436 5564 8.63E-8 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SUPERFAMILY SSF49299 4540 4632 1.31E-7 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SMART SM00089 4645 4731 3.3 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SMART SM00089 4734 4828 0.83 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SMART SM00089 5105 5192 0.38 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SMART SM00089 5476 5563 0.39 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SMART SM00089 5217 5292 9.5 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SMART SM00089 4549 4637 2.9 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SMART SM00089 5588 5663 14.0 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 Gene3D G3DSA:2.60.40.10 4735 4825 1.2E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SUPERFAMILY SSF49299 5073 5193 1.77E-7 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SUPERFAMILY SSF49299 4752 4825 1.96E-10 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 SUPERFAMILY SSF49299 4667 4730 1.03E-5 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 Gene3D G3DSA:2.60.40.10 4554 4638 1.8E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 Gene3D G3DSA:2.60.40.10 4650 4734 3.1E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 Gene3D G3DSA:2.60.40.10 5117 5193 3.6E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1006950 a2efcacfb6d40edb72c732e875f7fe24 6572 Gene3D G3DSA:2.60.40.10 5493 5564 6.9E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1012285 fa5e9f3ac6a83902e64ddde6decf6c60 581 Gene3D G3DSA:2.170.130.10 1 115 8.7E-35 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1012285 fa5e9f3ac6a83902e64ddde6decf6c60 581 Pfam PF07715 TonB-dependent Receptor Plug Domain 2 110 5.9E-26 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1012285 fa5e9f3ac6a83902e64ddde6decf6c60 581 Gene3D G3DSA:2.40.170.20 121 562 8.1E-108 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1012285 fa5e9f3ac6a83902e64ddde6decf6c60 581 SUPERFAMILY SSF56935 2 559 3.21E-106 T 13-10-2018 MADE_1012285 fa5e9f3ac6a83902e64ddde6decf6c60 581 Pfam PF00593 TonB dependent receptor 225 551 5.5E-46 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1009195 abd316c0d07c7d7ff3c90bda214e6ff6 315 Pfam PF00924 Mechanosensitive ion channel 69 178 8.4E-16 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1009195 abd316c0d07c7d7ff3c90bda214e6ff6 315 Gene3D G3DSA:2.30.30.60 118 174 8.1E-8 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1009195 abd316c0d07c7d7ff3c90bda214e6ff6 315 SUPERFAMILY SSF50182 103 174 3.6E-12 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1013475 50d619c350524a6af2a8b2c07c63c317 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 211 1.2E-18 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MADE_1013475 50d619c350524a6af2a8b2c07c63c317 228 SMART SM00855 3 171 1.1E-7 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 MADE_1013475 50d619c350524a6af2a8b2c07c63c317 228 Gene3D G3DSA:3.40.50.1240 1 221 5.7E-30 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_1013475 50d619c350524a6af2a8b2c07c63c317 228 SUPERFAMILY SSF53254 1 217 4.71E-34 T 13-10-2018 IPR029033 Histidine phosphatase superfamily MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 Gene3D G3DSA:3.30.70.270 475 666 5.9E-49 T 13-10-2018 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SMART SM00267 479 667 3.6E-39 T 13-10-2018 IPR000160 GGDEF domain MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SUPERFAMILY SSF48452 57 261 6.2E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 Pfam PF00990 Diguanylate cyclase, GGDEF domain 491 662 4.4E-36 T 13-10-2018 IPR000160 GGDEF domain MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 Gene3D G3DSA:1.25.40.10 39 141 2.4E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SUPERFAMILY SSF48452 239 336 6.54E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 Pfam PF13424 Tetratricopeptide repeat 111 183 2.5E-9 T 13-10-2018 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 Gene3D G3DSA:1.25.40.10 146 394 9.3E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SUPERFAMILY SSF55073 495 665 1.1E-35 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 486 664 1.6E-38 T 13-10-2018 IPR000160 GGDEF domain MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SMART SM00028 272 305 180.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SMART SM00028 112 145 18.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SMART SM00028 72 105 220.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SMART SM00028 152 185 33.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1015265 0323ea6d623f7c325a77ee153d4cf7fc 712 SMART SM00028 192 225 390.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1015035 627a7980e5387b46d350554525c6352c 250 Gene3D G3DSA:1.10.3900.10 12 178 1.4E-81 T 13-10-2018 MADE_1015035 627a7980e5387b46d350554525c6352c 250 Pfam PF07072 Cell division protein 18 225 3.6E-72 T 13-10-2018 IPR009777 Cell division protein ZapD MADE_1015035 627a7980e5387b46d350554525c6352c 250 SUPERFAMILY SSF160950 3 250 3.14E-81 T 13-10-2018 IPR036268 ZapD domain superfamily MADE_1015035 627a7980e5387b46d350554525c6352c 250 Gene3D G3DSA:2.60.440.10 5 250 1.4E-81 T 13-10-2018 IPR027462 Z ring-associated protein D, C-terminal MADE_1015035 627a7980e5387b46d350554525c6352c 250 Hamap MF_01092 Cell division protein ZapD [zapD]. 3 250 30.966 T 13-10-2018 IPR009777 Cell division protein ZapD MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 14 235 1.1E-107 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 PIRSF PIRSF000292 2 309 5.3E-129 T 13-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 SUPERFAMILY SSF49503 117 277 1.09E-49 T 13-10-2018 IPR008972 Cupredoxin MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 Pfam PF06481 COX Aromatic Rich Motif 235 280 8.9E-20 T 13-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 SUPERFAMILY SSF81464 15 113 6.38E-23 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 Gene3D G3DSA:2.60.40.420 109 277 1.9E-58 T 13-10-2018 IPR008972 Cupredoxin MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 144 214 3.7E-6 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019590 c352df370aea08cefd58a6d2700fdbd7 313 Gene3D G3DSA:1.10.287.90 24 108 5.9E-32 T 13-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016620 25d05fb135780f2e27656d677f4c4c6f 237 Gene3D G3DSA:3.60.10.10 2 235 9.2E-42 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1016620 25d05fb135780f2e27656d677f4c4c6f 237 SUPERFAMILY SSF56219 3 234 4.06E-35 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1016620 25d05fb135780f2e27656d677f4c4c6f 237 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 223 5.3E-15 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MADE_1010550 dc5d543e98eb208b78caad7c283cbce7 275 Pfam PF13276 HTH-like domain 28 84 2.4E-11 T 13-10-2018 IPR025948 HTH-like domain MADE_1010550 dc5d543e98eb208b78caad7c283cbce7 275 SUPERFAMILY SSF53098 102 265 5.01E-43 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1010550 dc5d543e98eb208b78caad7c283cbce7 275 Pfam PF00665 Integrase core domain 108 222 8.7E-35 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1010550 dc5d543e98eb208b78caad7c283cbce7 275 Gene3D G3DSA:3.30.420.10 106 270 1.0E-15 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1016180 dc5d543e98eb208b78caad7c283cbce7 275 Pfam PF13276 HTH-like domain 28 84 2.4E-11 T 13-10-2018 IPR025948 HTH-like domain MADE_1016180 dc5d543e98eb208b78caad7c283cbce7 275 SUPERFAMILY SSF53098 102 265 5.01E-43 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1016180 dc5d543e98eb208b78caad7c283cbce7 275 Pfam PF00665 Integrase core domain 108 222 8.7E-35 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1016180 dc5d543e98eb208b78caad7c283cbce7 275 Gene3D G3DSA:3.30.420.10 106 270 1.0E-15 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1003240 dc5d543e98eb208b78caad7c283cbce7 275 Pfam PF13276 HTH-like domain 28 84 2.4E-11 T 13-10-2018 IPR025948 HTH-like domain MADE_1003240 dc5d543e98eb208b78caad7c283cbce7 275 SUPERFAMILY SSF53098 102 265 5.01E-43 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1003240 dc5d543e98eb208b78caad7c283cbce7 275 Pfam PF00665 Integrase core domain 108 222 8.7E-35 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1003240 dc5d543e98eb208b78caad7c283cbce7 275 Gene3D G3DSA:3.30.420.10 106 270 1.0E-15 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_000001021905 cfa8f6cefebd9526be42716a6dda4fbf 148 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 3.0E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MADE_000001021905 cfa8f6cefebd9526be42716a6dda4fbf 148 PRINTS PR01651 Protein-export SecG membrane protein signature 39 55 3.0E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MADE_000001021905 cfa8f6cefebd9526be42716a6dda4fbf 148 PRINTS PR01651 Protein-export SecG membrane protein signature 24 38 3.0E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MADE_000001021905 cfa8f6cefebd9526be42716a6dda4fbf 148 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 3.0E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MADE_000001021905 cfa8f6cefebd9526be42716a6dda4fbf 148 Pfam PF03840 Preprotein translocase SecG subunit 5 73 3.1E-21 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MADE_000001021905 cfa8f6cefebd9526be42716a6dda4fbf 148 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 74 1.7E-25 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 SMART SM00344 3 112 6.0E-45 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 SUPERFAMILY SSF54909 63 152 6.3E-20 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 Gene3D G3DSA:1.10.10.10 4 55 5.4E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 SUPERFAMILY SSF46785 2 61 2.62E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 Gene3D G3DSA:3.30.70.920 56 140 4.9E-25 T 13-10-2018 MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 Pfam PF01037 Lrp/AsnC ligand binding domain 71 143 1.1E-19 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 1.3E-18 T 13-10-2018 MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 4.7E-15 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 4.7E-15 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1006195 9292bd6b7fe4638608a9a2066f87d34a 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 4.7E-15 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1001865 d7adfb770bc036c48b5989152a552f61 244 SUPERFAMILY SSF53448 2 226 9.7E-41 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1001865 d7adfb770bc036c48b5989152a552f61 244 Gene3D G3DSA:3.90.550.10 1 237 2.3E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1001865 d7adfb770bc036c48b5989152a552f61 244 Pfam PF00535 Glycosyl transferase family 2 4 162 9.4E-28 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1006150 5738d7a8adea06a70299ea8ac93a0e3f 578 PIRSF PIRSF002741 1 574 3.4E-99 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 MADE_1006150 5738d7a8adea06a70299ea8ac93a0e3f 578 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 83 105 - T 13-10-2018 IPR023765 Solute-binding protein family 5, conserved site MADE_1006150 5738d7a8adea06a70299ea8ac93a0e3f 578 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 494 2.5E-80 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain MADE_1006150 5738d7a8adea06a70299ea8ac93a0e3f 578 SUPERFAMILY SSF53850 35 574 5.25E-134 T 13-10-2018 MADE_1007795 80764ca2e28e1d167073aaeb090d48eb 115 Pfam PF03960 ArsC family 6 113 2.6E-17 T 13-10-2018 IPR006660 Arsenate reductase-like MADE_1007795 80764ca2e28e1d167073aaeb090d48eb 115 SUPERFAMILY SSF52833 4 114 5.06E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1007795 80764ca2e28e1d167073aaeb090d48eb 115 Gene3D G3DSA:3.40.30.10 2 115 8.0E-40 T 13-10-2018 MADE_1007795 80764ca2e28e1d167073aaeb090d48eb 115 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 112 4.2E-30 T 13-10-2018 IPR006504 Transcriptional regulator Spx/MgsR MADE_1010850 04136a8532af7c711cd262305f3cdadc 168 Gene3D G3DSA:3.40.30.10 32 168 3.0E-28 T 13-10-2018 MADE_1010850 04136a8532af7c711cd262305f3cdadc 168 SUPERFAMILY SSF52833 40 164 7.65E-28 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1010850 04136a8532af7c711cd262305f3cdadc 168 ProSitePatterns PS00194 Thioredoxin family active site. 59 77 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_1010850 04136a8532af7c711cd262305f3cdadc 168 Pfam PF00578 AhpC/TSA family 42 146 9.3E-15 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1007115 0a7a95c54a0a16cbbbe1c85baa1f6dce 149 Pfam PF00011 Hsp20/alpha crystallin family 45 142 4.9E-21 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain MADE_1007115 0a7a95c54a0a16cbbbe1c85baa1f6dce 149 Gene3D G3DSA:2.60.40.790 34 143 1.6E-25 T 13-10-2018 IPR008978 HSP20-like chaperone MADE_1007115 0a7a95c54a0a16cbbbe1c85baa1f6dce 149 SUPERFAMILY SSF49764 8 142 3.84E-24 T 13-10-2018 IPR008978 HSP20-like chaperone MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 Gene3D G3DSA:3.30.360.10 153 317 2.1E-130 T 13-10-2018 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 SUPERFAMILY SSF51735 2 175 4.87E-51 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 Gene3D G3DSA:3.40.50.720 4 327 2.1E-130 T 13-10-2018 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 SUPERFAMILY SSF55347 154 316 1.64E-59 T 13-10-2018 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 SMART SM00846 2 154 1.0E-73 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 315 6.9E-56 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 PIRSF PIRSF000149 1 336 9.2E-128 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 Hamap MF_01640 D-erythrose-4-phosphate dehydrogenase [epd]. 1 336 64.86 T 13-10-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 104 1.3E-35 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 4 327 9.3E-167 T 13-10-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 111 124 2.5E-30 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 2.5E-30 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 271 286 2.5E-30 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 148 166 2.5E-30 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004350 a7c0531e321f4b94b4161f77befd3c1b 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 175 191 2.5E-30 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1003965 720f5db46e743d172574e49699c586f5 674 SMART SM00304 345 397 1.5E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1003965 720f5db46e743d172574e49699c586f5 674 SMART SM00283 412 673 1.0E-64 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1003965 720f5db46e743d172574e49699c586f5 674 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 482 637 1.1E-41 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1003965 720f5db46e743d172574e49699c586f5 674 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 125 3.3E-9 T 13-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain MADE_1003965 720f5db46e743d172574e49699c586f5 674 Gene3D G3DSA:1.10.287.950 344 674 2.0E-73 T 13-10-2018 MADE_1003965 720f5db46e743d172574e49699c586f5 674 SUPERFAMILY SSF58104 365 674 3.4E-73 T 13-10-2018 MADE_000001022730 4e9eb3ee873938c15707ce3f121f17b6 291 Gene3D G3DSA:3.40.50.720 72 284 3.8E-18 T 13-10-2018 MADE_000001022730 4e9eb3ee873938c15707ce3f121f17b6 291 SUPERFAMILY SSF69572 71 197 6.28E-16 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MADE_000001022730 4e9eb3ee873938c15707ce3f121f17b6 291 Pfam PF00899 ThiF family 70 196 1.0E-9 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MADE_1004310 ab2728cc5ac5b9e987999822fe5f44a0 347 Pfam PF00892 EamA-like transporter family 197 327 5.5E-16 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1004310 ab2728cc5ac5b9e987999822fe5f44a0 347 Pfam PF00892 EamA-like transporter family 45 177 1.5E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1004310 ab2728cc5ac5b9e987999822fe5f44a0 347 SUPERFAMILY SSF103481 95 181 2.35E-7 T 13-10-2018 MADE_1004310 ab2728cc5ac5b9e987999822fe5f44a0 347 SUPERFAMILY SSF103481 234 329 9.68E-12 T 13-10-2018 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 Gene3D G3DSA:1.10.760.10 21 108 1.3E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 PRINTS PR00605 Class IC cytochrome C signature 81 103 3.5E-5 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 PRINTS PR00605 Class IC cytochrome C signature 32 43 3.5E-5 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 Gene3D G3DSA:1.10.760.10 111 207 1.9E-27 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 Pfam PF00034 Cytochrome c 29 106 9.4E-12 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 Pfam PF00034 Cytochrome c 120 205 3.9E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 PIRSF PIRSF000005 1 207 1.2E-64 T 13-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 SUPERFAMILY SSF46626 117 205 7.42E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1000065 3ab4fbb2abf1d58fb88233df57b23ba4 207 SUPERFAMILY SSF46626 5 109 1.6E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 498 5.9E-234 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 SUPERFAMILY SSF51569 1 291 1.25E-99 T 13-10-2018 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 Gene3D G3DSA:3.30.160.270 394 501 1.3E-12 T 13-10-2018 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 Gene3D G3DSA:3.20.20.70 1 276 4.1E-108 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 510 42.569 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 Gene3D G3DSA:1.10.238.260 280 393 3.3E-33 T 13-10-2018 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 SMART SM00917 369 501 1.6E-36 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 SUPERFAMILY SSF110921 389 499 3.27E-25 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 Pfam PF00682 HMGL-like 4 273 2.2E-97 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MADE_1004705 fa7062e52a069f138926884795ec2d73 519 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 500 2.3E-32 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 MADE_1000345 1cd78591181e76b7bc1c36dbf1f818ef 286 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 1 283 28.474 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MADE_1000345 1cd78591181e76b7bc1c36dbf1f818ef 286 Gene3D G3DSA:1.20.120.1780 165 285 8.2E-13 T 13-10-2018 MADE_1000345 1cd78591181e76b7bc1c36dbf1f818ef 286 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 5 282 4.9E-101 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 MADE_1000345 1cd78591181e76b7bc1c36dbf1f818ef 286 Gene3D G3DSA:1.10.357.140 20 164 9.7E-40 T 13-10-2018 MADE_1000345 1cd78591181e76b7bc1c36dbf1f818ef 286 Pfam PF01040 UbiA prenyltransferase family 23 264 4.3E-64 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MADE_1002965 076d750033eb431509c8cd1ff2b75e25 687 SUPERFAMILY SSF51445 104 407 2.84E-71 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1002965 076d750033eb431509c8cd1ff2b75e25 687 Gene3D G3DSA:3.40.50.1700 476 684 4.5E-14 T 13-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 MADE_1002965 076d750033eb431509c8cd1ff2b75e25 687 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 346 363 - T 13-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 MADE_1002965 076d750033eb431509c8cd1ff2b75e25 687 Gene3D G3DSA:3.20.20.300 66 450 6.2E-103 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MADE_1002965 076d750033eb431509c8cd1ff2b75e25 687 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 109 419 9.2E-81 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1012920 7583996d394371cd6df0ddbc4bb8b0a1 491 SUPERFAMILY SSF51905 8 217 3.29E-50 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1012920 7583996d394371cd6df0ddbc4bb8b0a1 491 Pfam PF00743 Flavin-binding monooxygenase-like 10 218 3.6E-13 T 13-10-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 MADE_1012920 7583996d394371cd6df0ddbc4bb8b0a1 491 SUPERFAMILY SSF51905 151 347 6.64E-27 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1012920 7583996d394371cd6df0ddbc4bb8b0a1 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 8.1E-5 T 13-10-2018 MADE_1012920 7583996d394371cd6df0ddbc4bb8b0a1 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 182 207 8.1E-5 T 13-10-2018 MADE_000001021675 7fd5ed0995d3852fbfe8bf41e6f925a3 152 SUPERFAMILY SSF55729 2 142 1.41E-26 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_000001021675 7fd5ed0995d3852fbfe8bf41e6f925a3 152 Pfam PF13673 Acetyltransferase (GNAT) domain 39 136 1.6E-7 T 13-10-2018 IPR000182 GNAT domain MADE_000001021675 7fd5ed0995d3852fbfe8bf41e6f925a3 152 Gene3D G3DSA:3.40.630.30 2 138 3.2E-24 T 13-10-2018 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 SMART SM00739 129 156 2.4E-7 T 13-10-2018 IPR005824 KOW MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 SUPERFAMILY SSF50104 127 182 9.03E-19 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 PRINTS PR00338 Transcription termination factor NUSG signature 141 156 1.0E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 PRINTS PR00338 Transcription termination factor NUSG signature 159 175 1.0E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 PRINTS PR00338 Transcription termination factor NUSG signature 63 75 1.0E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 8 183 24.173 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 Gene3D G3DSA:2.30.30.30 126 182 1.4E-25 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 Pfam PF02357 Transcription termination factor nusG 9 114 1.5E-25 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 Gene3D G3DSA:3.30.70.940 3 125 3.3E-46 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 ProSitePatterns PS01014 Transcription termination factor nusG signature. 166 175 - T 13-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 Pfam PF00467 KOW motif 132 162 1.9E-9 T 13-10-2018 IPR005824 KOW MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 11 182 4.7E-69 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 SMART SM00738 8 117 3.4E-47 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MADE_000001023340 ee21f0abd97d699ed945dfcfc2611a31 183 SUPERFAMILY SSF82679 8 119 3.14E-38 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 Gene3D G3DSA:3.30.420.40 194 393 1.2E-73 T 13-10-2018 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 PIRSF PIRSF000722 1 393 2.2E-133 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 SUPERFAMILY SSF53067 153 390 3.15E-81 T 13-10-2018 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 Hamap MF_00020 Acetate kinase [ackA]. 1 393 169.29 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 Gene3D G3DSA:3.30.420.40 2 191 6.7E-64 T 13-10-2018 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 TIGRFAM TIGR00016 ackA: acetate kinase 2 390 1.6E-144 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 SUPERFAMILY SSF53067 4 192 1.23E-59 T 13-10-2018 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 PRINTS PR00471 Acetate kinase family signature 169 182 2.7E-45 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 PRINTS PR00471 Acetate kinase family signature 5 16 2.7E-45 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 PRINTS PR00471 Acetate kinase family signature 318 334 2.7E-45 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 PRINTS PR00471 Acetate kinase family signature 374 386 2.7E-45 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 PRINTS PR00471 Acetate kinase family signature 296 309 2.7E-45 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 PRINTS PR00471 Acetate kinase family signature 199 220 2.7E-45 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 Pfam PF00871 Acetokinase family 5 386 4.5E-141 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1007120 f8e06f231ac8a1ed15db6d74960427bc 393 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 199 216 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 MADE_1019075 35a037aab7a6b91adbdf878f84b4ca48 526 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 502 1.3E-177 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MADE_1019075 35a037aab7a6b91adbdf878f84b4ca48 526 PIRSF PIRSF006446 1 519 4.1E-148 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MADE_1012625 1a4fbde64177e93f6cd0e6d162209fff 1355 SUPERFAMILY SSF53300 578 683 5.01E-5 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1012625 1a4fbde64177e93f6cd0e6d162209fff 1355 Gene3D G3DSA:3.40.50.410 41 215 1.4E-6 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1012625 1a4fbde64177e93f6cd0e6d162209fff 1355 SUPERFAMILY SSF50998 857 1212 9.42E-14 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily MADE_1012625 1a4fbde64177e93f6cd0e6d162209fff 1355 Pfam PF05567 Neisseria PilC beta-propeller domain 871 1087 4.4E-22 T 13-10-2018 IPR008707 PilC beta-propeller domain MADE_1012625 1a4fbde64177e93f6cd0e6d162209fff 1355 SUPERFAMILY SSF53300 42 103 5.64E-5 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1007720 fd1d55778e83a3b51fe3783cf7ec209b 282 Gene3D G3DSA:1.20.1080.10 1 249 1.2E-66 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MADE_1007720 fd1d55778e83a3b51fe3783cf7ec209b 282 Pfam PF01226 Formate/nitrite transporter 9 257 1.4E-64 T 13-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 MADE_1011815 21506774be02c27f84ef8b6c906175ae 134 Gene3D G3DSA:3.40.190.10 17 133 5.0E-12 T 13-10-2018 MADE_1011815 21506774be02c27f84ef8b6c906175ae 134 SUPERFAMILY SSF53850 16 131 7.33E-17 T 13-10-2018 MADE_1008305 3da9a6af54bb38a9f607cdb1b5bb45f5 340 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 12 286 6.3E-72 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 MADE_1008305 3da9a6af54bb38a9f607cdb1b5bb45f5 340 SUPERFAMILY SSF51445 3 293 6.21E-76 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1008305 3da9a6af54bb38a9f607cdb1b5bb45f5 340 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 3 339 46.253 T 13-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 MADE_1008305 3da9a6af54bb38a9f607cdb1b5bb45f5 340 Gene3D G3DSA:3.20.20.300 1 321 8.4E-107 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 SUPERFAMILY SSF52540 10 209 4.5E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 16 203 3.6E-40 T 13-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 Gene3D G3DSA:3.40.50.300 10 217 1.5E-62 T 13-10-2018 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 PRINTS PR00988 Uridine kinase signature 147 157 2.5E-27 T 13-10-2018 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 PRINTS PR00988 Uridine kinase signature 161 172 2.5E-27 T 13-10-2018 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 PRINTS PR00988 Uridine kinase signature 91 106 2.5E-27 T 13-10-2018 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 PRINTS PR00988 Uridine kinase signature 14 31 2.5E-27 T 13-10-2018 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 PRINTS PR00988 Uridine kinase signature 183 196 2.5E-27 T 13-10-2018 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 PRINTS PR00988 Uridine kinase signature 46 57 2.5E-27 T 13-10-2018 MADE_000001023050 4dc7cb4f87fd2336e0ed1f13da5e8519 217 TIGRFAM TIGR00235 udk: uridine kinase 12 215 2.4E-73 T 13-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 Gene3D G3DSA:3.30.365.10 53 186 2.7E-23 T 13-10-2018 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 330 590 1.2E-26 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 35 180 8.4E-16 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 619 709 7.3E-16 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 PIRSF PIRSF036389 6 762 3.6E-197 T 13-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 SUPERFAMILY SSF56003 297 763 2.91E-101 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 SUPERFAMILY SSF56003 53 244 2.69E-33 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 Gene3D G3DSA:3.30.365.10 359 450 3.4E-44 T 13-10-2018 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 Gene3D G3DSA:3.30.365.10 596 759 2.4E-37 T 13-10-2018 MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 SMART SM01008 219 305 7.5E-14 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MADE_1007890 da836b6c9ea5914c5bef9bc4c37502b6 765 Gene3D G3DSA:3.30.365.10 335 570 3.4E-44 T 13-10-2018 MADE_1005620 5a9812e6b92bff4ce802fb9e595bd672 131 SUPERFAMILY SSF46458 6 121 1.42E-18 T 13-10-2018 IPR009050 Globin-like superfamily MADE_1005620 5a9812e6b92bff4ce802fb9e595bd672 131 Gene3D G3DSA:1.10.490.10 5 126 7.2E-28 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MADE_1019570 f083ec46cea97467f5fcccd3828af86c 298 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 6 285 2.2E-82 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MADE_1019570 f083ec46cea97467f5fcccd3828af86c 298 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 59 81 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site MADE_1019570 f083ec46cea97467f5fcccd3828af86c 298 Gene3D G3DSA:1.10.357.140 16 184 9.8E-17 T 13-10-2018 MADE_1019570 f083ec46cea97467f5fcccd3828af86c 298 Pfam PF01040 UbiA prenyltransferase family 22 266 1.6E-53 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 MADE_1019570 f083ec46cea97467f5fcccd3828af86c 298 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 4 287 17.068 T 13-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 MADE_1018925 39110db297b0519ef7e8d834e91d2741 214 Pfam PF03473 MOSC domain 50 162 2.0E-18 T 13-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 MADE_1018925 39110db297b0519ef7e8d834e91d2741 214 SUPERFAMILY SSF50800 5 211 1.36E-50 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily MADE_1018925 39110db297b0519ef7e8d834e91d2741 214 Gene3D G3DSA:2.40.33.20 4 214 5.0E-58 T 13-10-2018 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Gene3D G3DSA:3.30.565.10 212 375 2.7E-50 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1011565 0900025faa427d2f9884b19f55478115 702 Gene3D G3DSA:3.40.50.2300 582 702 2.5E-23 T 13-10-2018 MADE_1011565 0900025faa427d2f9884b19f55478115 702 SUPERFAMILY SSF52172 405 525 4.41E-30 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1011565 0900025faa427d2f9884b19f55478115 702 SMART SM00387 257 376 3.9E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011565 0900025faa427d2f9884b19f55478115 702 SUPERFAMILY SSF52172 591 701 5.27E-25 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1011565 0900025faa427d2f9884b19f55478115 702 SUPERFAMILY SSF52172 5 137 2.42E-22 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1011565 0900025faa427d2f9884b19f55478115 702 Pfam PF00072 Response regulator receiver domain 7 109 5.8E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Pfam PF00072 Response regulator receiver domain 406 518 1.0E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Pfam PF00072 Response regulator receiver domain 594 700 6.5E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011565 0900025faa427d2f9884b19f55478115 702 SUPERFAMILY SSF47384 136 210 3.34E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Gene3D G3DSA:1.10.287.130 138 211 6.0E-21 T 13-10-2018 MADE_1011565 0900025faa427d2f9884b19f55478115 702 SMART SM00448 5 120 1.3E-14 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011565 0900025faa427d2f9884b19f55478115 702 SMART SM00448 404 520 8.6E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011565 0900025faa427d2f9884b19f55478115 702 SMART SM00448 592 701 2.3E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Gene3D G3DSA:3.40.50.2300 1 137 2.2E-21 T 13-10-2018 MADE_1011565 0900025faa427d2f9884b19f55478115 702 SMART SM00388 145 210 4.3E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Gene3D G3DSA:3.40.50.2300 404 525 3.5E-32 T 13-10-2018 MADE_1011565 0900025faa427d2f9884b19f55478115 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 354 1.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011565 0900025faa427d2f9884b19f55478115 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 329 1.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011565 0900025faa427d2f9884b19f55478115 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 315 1.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011565 0900025faa427d2f9884b19f55478115 702 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 1.7E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Pfam PF00512 His Kinase A (phospho-acceptor) domain 146 209 4.5E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1011565 0900025faa427d2f9884b19f55478115 702 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 373 1.1E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1011565 0900025faa427d2f9884b19f55478115 702 SUPERFAMILY SSF55874 199 372 6.81E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1019545 d056cf681b95ffb7866180649505c225 1074 SMART SM00965 102 153 6.2E-8 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MADE_1019545 d056cf681b95ffb7866180649505c225 1074 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 191 1073 5.1E-180 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_1019545 d056cf681b95ffb7866180649505c225 1074 Pfam PF07715 TonB-dependent Receptor Plug Domain 209 311 2.7E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1019545 d056cf681b95ffb7866180649505c225 1074 Gene3D G3DSA:3.55.50.30 78 162 2.9E-18 T 13-10-2018 MADE_1019545 d056cf681b95ffb7866180649505c225 1074 Pfam PF00593 TonB dependent receptor 598 1072 1.0E-30 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1019545 d056cf681b95ffb7866180649505c225 1074 Gene3D G3DSA:2.40.170.20 593 1074 7.0E-31 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1019545 d056cf681b95ffb7866180649505c225 1074 Gene3D G3DSA:2.170.130.10 178 315 1.4E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1019545 d056cf681b95ffb7866180649505c225 1074 SUPERFAMILY SSF56935 185 1074 6.54E-70 T 13-10-2018 MADE_000001023570 572236170bab873ccb1b7d6f86d2b626 160 Gene3D G3DSA:3.40.50.300 5 159 9.8E-44 T 13-10-2018 MADE_000001023570 572236170bab873ccb1b7d6f86d2b626 160 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 20 145 2.9E-44 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MADE_000001023570 572236170bab873ccb1b7d6f86d2b626 160 SUPERFAMILY SSF52540 26 134 1.77E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023570 572236170bab873ccb1b7d6f86d2b626 160 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 12 134 1.1E-38 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 MADE_1002425 a3eacd4463d04b47b1aecf4e34acbf32 415 Pfam PF00909 Ammonium Transporter Family 16 407 3.5E-97 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 MADE_1002425 a3eacd4463d04b47b1aecf4e34acbf32 415 SUPERFAMILY SSF111352 10 388 4.84E-100 T 13-10-2018 MADE_1002425 a3eacd4463d04b47b1aecf4e34acbf32 415 ProSitePatterns PS01219 Ammonium transporters signature. 168 193 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 MADE_1002425 a3eacd4463d04b47b1aecf4e34acbf32 415 Gene3D G3DSA:1.10.3430.10 4 414 1.7E-118 T 13-10-2018 IPR029020 Ammonium/urea transporter MADE_1002425 a3eacd4463d04b47b1aecf4e34acbf32 415 TIGRFAM TIGR03644 marine_trans_1: probable ammonium transporter, marine subtype 9 410 3.5E-200 T 13-10-2018 IPR019879 Ammonium transporter, marine subtype MADE_1009760 59315b260e3944656faae60b37aec9aa 252 SUPERFAMILY SSF51735 8 236 8.28E-65 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1009760 59315b260e3944656faae60b37aec9aa 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1009760 59315b260e3944656faae60b37aec9aa 252 Gene3D G3DSA:3.40.50.720 6 250 1.4E-67 T 13-10-2018 MADE_1009760 59315b260e3944656faae60b37aec9aa 252 Pfam PF00106 short chain dehydrogenase 12 204 5.2E-52 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.7E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 4.7E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 4.7E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.7E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.7E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.6E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.6E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.6E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009760 59315b260e3944656faae60b37aec9aa 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 196 3.6E-6 T 13-10-2018 MADE_1013040 cb9cbca745f720b0a0d56a70d606038f 306 Hamap MF_00313 Glutaminase [glsA]. 5 306 44.499 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MADE_1013040 cb9cbca745f720b0a0d56a70d606038f 306 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 306 1.8E-124 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MADE_1013040 cb9cbca745f720b0a0d56a70d606038f 306 SUPERFAMILY SSF56601 6 306 5.83E-108 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1013040 cb9cbca745f720b0a0d56a70d606038f 306 Pfam PF04960 Glutaminase 23 306 4.4E-110 T 13-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 MADE_1013040 cb9cbca745f720b0a0d56a70d606038f 306 Gene3D G3DSA:3.40.710.10 2 306 1.5E-108 T 13-10-2018 MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 SUPERFAMILY SSF52738 156 344 3.14E-49 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 Pfam PF00072 Response regulator receiver domain 5 105 5.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 Pfam PF01339 CheB methylesterase 160 340 4.3E-48 T 13-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 Gene3D G3DSA:3.40.50.2300 2 130 1.1E-29 T 13-10-2018 MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 Gene3D G3DSA:3.40.50.180 152 343 3.6E-51 T 13-10-2018 IPR035909 Methylesterase CheB, C-terminal MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 SMART SM00448 3 117 2.8E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 PIRSF PIRSF000876 1 345 8.7E-104 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 345 31.057 T 13-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 MADE_1015090 9e79fed39c0544f78bcb09d779ae28b7 345 SUPERFAMILY SSF52172 2 105 7.26E-29 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001022405 cb803b5b48fd89b175f2859c56df2ba3 757 Gene3D G3DSA:2.130.10.80 180 301 1.9E-15 T 13-10-2018 IPR037293 Galactose oxidase, central domain superfamily MADE_000001022405 cb803b5b48fd89b175f2859c56df2ba3 757 Gene3D G3DSA:2.130.10.80 302 641 4.7E-36 T 13-10-2018 IPR037293 Galactose oxidase, central domain superfamily MADE_000001022405 cb803b5b48fd89b175f2859c56df2ba3 757 SUPERFAMILY SSF50965 201 606 6.28E-27 T 13-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller MADE_000001022405 cb803b5b48fd89b175f2859c56df2ba3 757 SUPERFAMILY SSF81296 637 748 2.8E-15 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_000001022405 cb803b5b48fd89b175f2859c56df2ba3 757 Pfam PF09118 Domain of unknown function (DUF1929) 641 748 1.8E-13 T 13-10-2018 IPR015202 Galactose oxidase-like, Early set domain MADE_000001022405 cb803b5b48fd89b175f2859c56df2ba3 757 Gene3D G3DSA:2.60.40.10 642 749 1.1E-18 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1002455 01fc4fccc2d66aa7b804c8076666bd7e 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 3.9E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1002455 01fc4fccc2d66aa7b804c8076666bd7e 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 3.9E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1002455 01fc4fccc2d66aa7b804c8076666bd7e 220 Gene3D G3DSA:1.10.357.10 67 205 5.6E-27 T 13-10-2018 MADE_1002455 01fc4fccc2d66aa7b804c8076666bd7e 220 Gene3D G3DSA:1.10.10.60 7 63 1.6E-19 T 13-10-2018 MADE_1002455 01fc4fccc2d66aa7b804c8076666bd7e 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.8E-17 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1002455 01fc4fccc2d66aa7b804c8076666bd7e 220 SUPERFAMILY SSF46689 9 70 1.65E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1013590 bd3025c99183c62414fef952226a0c33 329 PIRSF PIRSF034367 2 329 1.6E-181 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 MADE_1013590 bd3025c99183c62414fef952226a0c33 329 Pfam PF08908 Domain of unknown function (DUF1852) 6 325 7.3E-174 T 13-10-2018 IPR015004 Protein of unknown function DUF1852 MADE_1007870 0e36d4038515a5babe86bd63237c9120 377 Pfam PF13533 Biotin-lipoyl like 69 113 3.8E-8 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_1007870 0e36d4038515a5babe86bd63237c9120 377 Gene3D G3DSA:1.10.287.470 100 158 3.2E-68 T 13-10-2018 MADE_1007870 0e36d4038515a5babe86bd63237c9120 377 Gene3D G3DSA:2.40.50.100 66 198 3.2E-68 T 13-10-2018 MADE_1007870 0e36d4038515a5babe86bd63237c9120 377 Gene3D G3DSA:2.40.30.170 52 283 3.2E-68 T 13-10-2018 MADE_1007870 0e36d4038515a5babe86bd63237c9120 377 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 53 371 2.3E-59 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1007870 0e36d4038515a5babe86bd63237c9120 377 Gene3D G3DSA:2.40.420.20 47 368 3.2E-68 T 13-10-2018 MADE_1007870 0e36d4038515a5babe86bd63237c9120 377 SUPERFAMILY SSF111369 56 223 1.57E-26 T 13-10-2018 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 Gene3D G3DSA:3.40.50.300 468 699 3.5E-69 T 13-10-2018 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 Pfam PF00664 ABC transporter transmembrane region 176 439 6.9E-18 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 SUPERFAMILY SSF90123 160 470 8.5E-48 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 Pfam PF03412 Peptidase C39 family 26 142 6.0E-9 T 13-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 ProSitePatterns PS00211 ABC transporters family signature. 625 639 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 Gene3D G3DSA:3.90.70.10 22 143 2.2E-32 T 13-10-2018 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 25 692 2.5E-239 T 13-10-2018 IPR017750 ATPase, type I secretion system MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 Gene3D G3DSA:1.20.1560.10 160 467 9.3E-49 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 Pfam PF00005 ABC transporter 504 653 2.1E-36 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 SMART SM00382 513 699 2.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005490 aae5aa992c6a1fc855ded4998e21be2f 699 SUPERFAMILY SSF52540 479 693 9.0E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008930 0ca85f2b59be72527c577a040c89a1e6 323 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 218 1.7E-80 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008930 0ca85f2b59be72527c577a040c89a1e6 323 Gene3D G3DSA:3.30.2350.10 1 245 1.1E-87 T 13-10-2018 MADE_1008930 0ca85f2b59be72527c577a040c89a1e6 323 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 244 4.2E-20 T 13-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 MADE_1008930 0ca85f2b59be72527c577a040c89a1e6 323 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 179 1.2E-55 T 13-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 MADE_1008930 0ca85f2b59be72527c577a040c89a1e6 323 SUPERFAMILY SSF55120 9 244 3.45E-76 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008930 0ca85f2b59be72527c577a040c89a1e6 323 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 248 297 3.0E-5 T 13-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1008930 0ca85f2b59be72527c577a040c89a1e6 323 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 320 17.796 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 Gene3D G3DSA:3.40.190.80 157 264 6.3E-22 T 13-10-2018 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 SUPERFAMILY SSF56655 7 270 4.97E-74 T 13-10-2018 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 9 261 37.125 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 10 259 2.9E-88 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 Pfam PF00459 Inositol monophosphatase family 9 252 3.7E-49 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 Gene3D G3DSA:3.30.540.10 5 156 1.1E-45 T 13-10-2018 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 88 104 2.5E-13 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 2.5E-13 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 2.5E-13 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 184 205 2.5E-13 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1019905 230e396c98904fddaaaf6bf9d09b0950 281 PRINTS PR00377 Inositol monophosphatase superfamily signature 216 240 2.5E-13 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1019430 f0564a9456325992a7739e90a531a0bb 146 Pfam PF01814 Hemerythrin HHE cation binding domain 12 127 4.0E-16 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 MADE_1019430 f0564a9456325992a7739e90a531a0bb 146 Gene3D G3DSA:1.20.120.520 14 145 3.0E-21 T 13-10-2018 MADE_1000885 41a9437fe37ec49556598b60421a6f53 238 Pfam PF07386 Protein of unknown function (DUF1499) 96 231 7.5E-31 T 13-10-2018 IPR010865 Protein of unknown function DUF1499 MADE_1013715 5900cb336d407b731c72e0334fdc4440 152 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 1.3E-50 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 MADE_1013715 5900cb336d407b731c72e0334fdc4440 152 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 32.259 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 MADE_1018050 a83605a4b0a57a338c4b556f11e1385f 787 Pfam PF00593 TonB dependent receptor 315 764 1.4E-28 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1018050 a83605a4b0a57a338c4b556f11e1385f 787 SUPERFAMILY SSF56935 34 787 3.89E-95 T 13-10-2018 MADE_1018050 a83605a4b0a57a338c4b556f11e1385f 787 Gene3D G3DSA:2.40.170.20 455 787 1.7E-54 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1018050 a83605a4b0a57a338c4b556f11e1385f 787 Gene3D G3DSA:2.40.170.20 49 413 1.0E-41 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1018050 a83605a4b0a57a338c4b556f11e1385f 787 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 164 8.9E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1011885 43933dbc47fc198492f75700717767d1 203 Gene3D G3DSA:3.30.70.1070 119 195 2.3E-8 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MADE_1011885 43933dbc47fc198492f75700717767d1 203 Pfam PF05036 Sporulation related domain 125 189 2.3E-12 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 MADE_1011885 43933dbc47fc198492f75700717767d1 203 SUPERFAMILY SSF110997 123 195 1.96E-14 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MADE_1015105 068efd581a86b8f19ff46bbb262ff57b 127 PRINTS PR00502 NUDIX hydrolase family signature 32 46 4.7E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MADE_1015105 068efd581a86b8f19ff46bbb262ff57b 127 PRINTS PR00502 NUDIX hydrolase family signature 46 61 4.7E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 MADE_1015105 068efd581a86b8f19ff46bbb262ff57b 127 Gene3D G3DSA:3.90.79.10 1 126 1.3E-35 T 13-10-2018 MADE_1015105 068efd581a86b8f19ff46bbb262ff57b 127 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MADE_1015105 068efd581a86b8f19ff46bbb262ff57b 127 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 126 4.9E-37 T 13-10-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 MADE_1015105 068efd581a86b8f19ff46bbb262ff57b 127 SUPERFAMILY SSF55811 1 126 1.23E-35 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_1015105 068efd581a86b8f19ff46bbb262ff57b 127 Pfam PF00293 NUDIX domain 5 122 5.7E-17 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MADE_1015420 a41f7aadfe0531c767dc3d6210cb8f5e 175 Gene3D G3DSA:1.10.260.40 2 73 1.0E-17 T 13-10-2018 MADE_1015420 a41f7aadfe0531c767dc3d6210cb8f5e 175 Gene3D G3DSA:2.60.120.10 80 174 1.2E-16 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1015420 a41f7aadfe0531c767dc3d6210cb8f5e 175 SUPERFAMILY SSF51182 77 169 5.35E-14 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1015420 a41f7aadfe0531c767dc3d6210cb8f5e 175 Pfam PF01381 Helix-turn-helix 13 66 7.2E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1015420 a41f7aadfe0531c767dc3d6210cb8f5e 175 SUPERFAMILY SSF47413 6 70 5.35E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1015420 a41f7aadfe0531c767dc3d6210cb8f5e 175 SMART SM00530 12 67 2.3E-13 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1007485 7f6f455d46d9686e043aa748520dfe9c 281 Gene3D G3DSA:3.20.20.370 7 276 2.2E-49 T 13-10-2018 MADE_1007485 7f6f455d46d9686e043aa748520dfe9c 281 Pfam PF11959 Domain of unknown function (DUF3473) 150 275 3.5E-42 T 13-10-2018 IPR022560 Domain of unknown function DUF3473 MADE_1007485 7f6f455d46d9686e043aa748520dfe9c 281 TIGRFAM TIGR03006 pepcterm_polyde: polysaccharide deacetylase family protein, PEP-CTERM locus subfamily 8 274 7.1E-121 T 13-10-2018 IPR014344 PEP-CTERM locus, polysaccharide deactylase MADE_1007485 7f6f455d46d9686e043aa748520dfe9c 281 Pfam PF01522 Polysaccharide deacetylase 33 148 2.4E-22 T 13-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 MADE_1007485 7f6f455d46d9686e043aa748520dfe9c 281 SUPERFAMILY SSF88713 16 256 3.46E-46 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 9 328 2.1E-140 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 Gene3D G3DSA:3.20.20.70 1 334 6.2E-146 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 SUPERFAMILY SSF51569 5 331 1.34E-143 T 13-10-2018 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 SMART SM01004 6 330 2.7E-240 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 157 176 9.1E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 274 289 9.1E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 126 140 9.1E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 249 265 9.1E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 304 323 9.1E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 195 214 9.1E-58 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 249 261 - T 13-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1002840 89a2c64cca2d12938392077b5f6f86f7 336 PIRSF PIRSF001415 1 333 1.3E-149 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 MADE_1009700 4683730b6db78a0e29f8e79ffabd9598 227 Pfam PF12945 Flagellar protein YcgR 23 112 9.6E-10 T 13-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal MADE_1009700 4683730b6db78a0e29f8e79ffabd9598 227 SUPERFAMILY SSF141371 131 222 5.89E-10 T 13-10-2018 MADE_1009700 4683730b6db78a0e29f8e79ffabd9598 227 SUPERFAMILY SSF141371 16 121 1.8E-22 T 13-10-2018 MADE_1009700 4683730b6db78a0e29f8e79ffabd9598 227 Gene3D G3DSA:2.30.110.10 8 121 4.5E-14 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_1009700 4683730b6db78a0e29f8e79ffabd9598 227 Pfam PF07238 PilZ domain 125 213 7.9E-10 T 13-10-2018 IPR009875 PilZ domain GO:0035438 MADE_1009700 4683730b6db78a0e29f8e79ffabd9598 227 Gene3D G3DSA:2.40.10.220 129 224 5.4E-7 T 13-10-2018 MADE_1010385 7de0cf4aeeb5942c72f469a9a87f5170 157 Pfam PF00034 Cytochrome c 33 131 3.1E-4 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1010385 7de0cf4aeeb5942c72f469a9a87f5170 157 Gene3D G3DSA:1.10.760.10 1 137 8.7E-9 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1010385 7de0cf4aeeb5942c72f469a9a87f5170 157 SUPERFAMILY SSF46626 1 132 4.28E-12 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1012475 dd25c922781d715e312fad8beb97afc7 135 SUPERFAMILY SSF141371 1 128 1.8E-19 T 13-10-2018 MADE_1012475 dd25c922781d715e312fad8beb97afc7 135 Pfam PF07238 PilZ domain 4 109 7.1E-7 T 13-10-2018 IPR009875 PilZ domain GO:0035438 MADE_1012475 dd25c922781d715e312fad8beb97afc7 135 Gene3D G3DSA:2.40.10.220 1 131 3.2E-26 T 13-10-2018 MADE_1004090 255ac76b49c95d8dfb4a332e9a20a15b 251 Pfam PF12261 Thermostable hemolysin 38 208 2.7E-46 T 13-10-2018 IPR022050 Thermostable hemolysin MADE_1012570 96b7a4cd360da3a3700796e7cdd49830 347 PIRSF PIRSF006487 12 293 3.1E-7 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 MADE_1012570 96b7a4cd360da3a3700796e7cdd49830 347 Gene3D G3DSA:2.40.30.160 209 326 1.1E-32 T 13-10-2018 MADE_1012570 96b7a4cd360da3a3700796e7cdd49830 347 Gene3D G3DSA:3.30.70.1400 22 106 3.2E-16 T 13-10-2018 MADE_1012570 96b7a4cd360da3a3700796e7cdd49830 347 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 200 263 1.6E-21 T 13-10-2018 IPR017703 YgfZ/GcvT conserved site MADE_1012570 96b7a4cd360da3a3700796e7cdd49830 347 SUPERFAMILY SSF103025 11 254 1.73E-40 T 13-10-2018 MADE_1012570 96b7a4cd360da3a3700796e7cdd49830 347 SUPERFAMILY SSF101790 255 336 2.03E-16 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal MADE_1012570 96b7a4cd360da3a3700796e7cdd49830 347 Pfam PF01571 Aminomethyltransferase folate-binding domain 15 112 1.3E-7 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain MADE_1014030 a17e19a67e745c6ea88cfdb7281d5d13 560 SUPERFAMILY SSF47203 295 448 2.9E-39 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1014030 a17e19a67e745c6ea88cfdb7281d5d13 560 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 186 280 8.1E-14 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1014030 a17e19a67e745c6ea88cfdb7281d5d13 560 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 290 445 2.0E-28 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1014030 a17e19a67e745c6ea88cfdb7281d5d13 560 Gene3D G3DSA:2.40.110.20 136 290 2.1E-55 T 13-10-2018 MADE_1014030 a17e19a67e745c6ea88cfdb7281d5d13 560 SUPERFAMILY SSF56645 77 299 7.61E-33 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1014030 a17e19a67e745c6ea88cfdb7281d5d13 560 Gene3D G3DSA:1.20.140.10 291 447 1.4E-35 T 13-10-2018 MADE_1002780 7004e95864bb4f5fedc822baba41ff14 153 SUPERFAMILY SSF54637 8 149 1.7E-22 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1002780 7004e95864bb4f5fedc822baba41ff14 153 Pfam PF14539 Domain of unknown function (DUF4442) 19 149 2.9E-51 T 13-10-2018 IPR027961 Protein of unknown function DUF4442 MADE_1002780 7004e95864bb4f5fedc822baba41ff14 153 Gene3D G3DSA:3.10.129.10 10 152 1.1E-38 T 13-10-2018 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 Pfam PF00815 Histidinol dehydrogenase 22 426 1.0E-163 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 31 425 2.0E-159 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 Gene3D G3DSA:3.40.50.1980 28 231 1.1E-118 T 13-10-2018 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 229 261 - T 13-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PIRSF PIRSF000099 1 429 1.2E-160 T 13-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 319 344 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 251 270 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 360 378 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 31 55 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 167 193 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 229 250 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 132 158 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 PRINTS PR00083 Histidinol dehydrogenase signature 197 222 7.0E-97 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 Gene3D G3DSA:3.40.50.1980 233 348 1.1E-118 T 13-10-2018 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 SUPERFAMILY SSF53720 3 426 3.14E-86 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1012300 442e7bc1ad1df1848de552e9dca6604e 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 426 39.773 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 MADE_1002950 36918381926cbe3b123e159484ec6ad3 156 Pfam PF01936 NYN domain 4 150 7.3E-38 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type MADE_1002950 36918381926cbe3b123e159484ec6ad3 156 Gene3D G3DSA:3.40.50.1010 2 156 2.4E-49 T 13-10-2018 MADE_000001022390 39ee904695cf0f86b133e532ea788048 73 Pfam PF13744 Helix-turn-helix domain 6 62 8.2E-8 T 13-10-2018 IPR039554 HigA2-like, helix-turn-helix domain MADE_000001022390 39ee904695cf0f86b133e532ea788048 73 SUPERFAMILY SSF47413 5 67 6.57E-9 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_000001022390 39ee904695cf0f86b133e532ea788048 73 Gene3D G3DSA:1.10.260.40 1 64 7.3E-10 T 13-10-2018 MADE_1016175 c55ee7e86ab1eae9197232873ecb8b9c 97 Gene3D G3DSA:1.10.10.60 8 89 1.9E-14 T 13-10-2018 MADE_1016175 c55ee7e86ab1eae9197232873ecb8b9c 97 SUPERFAMILY SSF46689 3 95 5.55E-23 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1016175 c55ee7e86ab1eae9197232873ecb8b9c 97 Pfam PF01527 Transposase 1 75 3.1E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1010545 c55ee7e86ab1eae9197232873ecb8b9c 97 Gene3D G3DSA:1.10.10.60 8 89 1.9E-14 T 13-10-2018 MADE_1010545 c55ee7e86ab1eae9197232873ecb8b9c 97 SUPERFAMILY SSF46689 3 95 5.55E-23 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1010545 c55ee7e86ab1eae9197232873ecb8b9c 97 Pfam PF01527 Transposase 1 75 3.1E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1003235 c55ee7e86ab1eae9197232873ecb8b9c 97 Gene3D G3DSA:1.10.10.60 8 89 1.9E-14 T 13-10-2018 MADE_1003235 c55ee7e86ab1eae9197232873ecb8b9c 97 SUPERFAMILY SSF46689 3 95 5.55E-23 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1003235 c55ee7e86ab1eae9197232873ecb8b9c 97 Pfam PF01527 Transposase 1 75 3.1E-17 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1015940 cea81812cdbf7af69a420e744d66c0af 558 Gene3D G3DSA:1.10.3080.10 12 425 1.9E-80 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MADE_1015940 cea81812cdbf7af69a420e744d66c0af 558 PRINTS PR00762 Chloride channel signature 163 182 4.6E-13 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MADE_1015940 cea81812cdbf7af69a420e744d66c0af 558 PRINTS PR00762 Chloride channel signature 358 374 4.6E-13 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MADE_1015940 cea81812cdbf7af69a420e744d66c0af 558 PRINTS PR00762 Chloride channel signature 112 131 4.6E-13 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MADE_1015940 cea81812cdbf7af69a420e744d66c0af 558 Pfam PF00654 Voltage gated chloride channel 87 407 2.4E-65 T 13-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 MADE_1015940 cea81812cdbf7af69a420e744d66c0af 558 SUPERFAMILY SSF81340 9 428 4.84E-80 T 13-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 MADE_1011650 bb28cb687ae840815ca37383c42f7988 142 Gene3D G3DSA:2.170.150.20 1 139 2.0E-59 T 13-10-2018 MADE_1011650 bb28cb687ae840815ca37383c42f7988 142 SUPERFAMILY SSF51316 13 139 2.58E-57 T 13-10-2018 IPR011057 Mss4-like superfamily MADE_1011650 bb28cb687ae840815ca37383c42f7988 142 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 12 140 6.4E-53 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MADE_1011650 bb28cb687ae840815ca37383c42f7988 142 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 12 135 35.703 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MADE_1011650 bb28cb687ae840815ca37383c42f7988 142 Pfam PF01641 SelR domain 15 133 4.0E-52 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 13-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 TIGRFAM TIGR01027 proB: glutamate 5-kinase 7 352 3.5E-97 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 Pfam PF00696 Amino acid kinase family 7 234 2.6E-38 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 PRINTS PR00474 Glutamate 5-kinase family signature 114 135 1.8E-38 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 PRINTS PR00474 Glutamate 5-kinase family signature 146 173 1.8E-38 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 1.8E-38 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 1.8E-38 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 PIRSF PIRSF000729 2 367 3.5E-100 T 13-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 Hamap MF_00456 Glutamate 5-kinase [proB]. 7 258 31.264 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 Gene3D G3DSA:2.30.130.10 265 364 7.3E-11 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 SUPERFAMILY SSF88697 276 345 4.9E-9 T 13-10-2018 IPR015947 PUA-like superfamily MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 Gene3D G3DSA:3.40.1160.10 2 264 1.7E-76 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_000001021970 135e24f14b339c84d0c60c1e0289ae5e 369 SUPERFAMILY SSF53633 7 256 3.14E-59 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1004510 a50a48bfbcb2ed5451ddb662178dbbe6 538 Pfam PF00221 Aromatic amino acid lyase 37 501 1.4E-182 T 13-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 MADE_1004510 a50a48bfbcb2ed5451ddb662178dbbe6 538 SUPERFAMILY SSF48557 29 529 4.79E-191 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 MADE_1004510 a50a48bfbcb2ed5451ddb662178dbbe6 538 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 33 533 2.3E-212 T 13-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1004510 a50a48bfbcb2ed5451ddb662178dbbe6 538 Gene3D G3DSA:1.20.200.10 224 537 2.7E-120 T 13-10-2018 MADE_1004510 a50a48bfbcb2ed5451ddb662178dbbe6 538 Gene3D G3DSA:1.10.275.10 29 223 5.9E-67 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal MADE_1004510 a50a48bfbcb2ed5451ddb662178dbbe6 538 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 165 181 - T 13-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 MADE_1004510 a50a48bfbcb2ed5451ddb662178dbbe6 538 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 29 534 43.965 T 13-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 MADE_1010845 b61b7831032de15cc294b2d5d384827e 487 Gene3D G3DSA:1.25.40.10 353 437 1.2E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1010845 b61b7831032de15cc294b2d5d384827e 487 SUPERFAMILY SSF48452 291 462 2.23E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1010845 b61b7831032de15cc294b2d5d384827e 487 Pfam PF01435 Peptidase family M48 75 261 3.0E-31 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MADE_1010845 b61b7831032de15cc294b2d5d384827e 487 Gene3D G3DSA:3.30.2010.10 75 154 3.8E-8 T 13-10-2018 MADE_1010845 b61b7831032de15cc294b2d5d384827e 487 Gene3D G3DSA:1.25.40.10 244 352 1.1E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1010845 b61b7831032de15cc294b2d5d384827e 487 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 4 487 41.231 T 13-10-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 Pfam PF00270 DEAD/DEAH box helicase 25 195 4.8E-44 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 Gene3D G3DSA:3.40.50.300 1 209 3.8E-69 T 13-10-2018 MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 Hamap MF_00967 ATP-dependent RNA helicase SrmB [srmB]. 1 408 49.704 T 13-10-2018 IPR028621 ATP-dependent RNA helicase SrmB GO:0000027|GO:0004004 MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 SMART SM00490 259 340 8.2E-33 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 Pfam PF00271 Helicase conserved C-terminal domain 233 340 4.7E-34 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 SMART SM00487 20 222 2.1E-53 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 SUPERFAMILY SSF52540 74 357 7.77E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MADE_1004665 40b00654f1b7f407dad651228e8e0251 408 Gene3D G3DSA:3.40.50.300 216 385 6.6E-52 T 13-10-2018 MADE_1013980 6ffa9a6120c0e268e47b45bdc4210c06 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 121 4.3E-43 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1013980 6ffa9a6120c0e268e47b45bdc4210c06 121 Gene3D G3DSA:3.30.420.100 5 121 4.9E-45 T 13-10-2018 MADE_1013980 6ffa9a6120c0e268e47b45bdc4210c06 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 121 26.133 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1013980 6ffa9a6120c0e268e47b45bdc4210c06 121 SUPERFAMILY SSF53137 7 119 5.67E-53 T 13-10-2018 MADE_1013980 6ffa9a6120c0e268e47b45bdc4210c06 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 5 121 1.4E-42 T 13-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021725 c6ee9ccb60a1f8878ba33f3602ae3334 106 Gene3D G3DSA:3.30.1390.10 1 106 2.1E-45 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MADE_000001021725 c6ee9ccb60a1f8878ba33f3602ae3334 106 SUPERFAMILY SSF54736 21 105 1.73E-34 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like MADE_000001021725 c6ee9ccb60a1f8878ba33f3602ae3334 106 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 10 101 28.769 T 13-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS MADE_000001021725 c6ee9ccb60a1f8878ba33f3602ae3334 106 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 24 102 9.5E-36 T 13-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 MADE_1010685 e07ab95a30c9c0df8cfe8d509c8ee83b 248 Gene3D G3DSA:3.90.1680.10 2 228 4.4E-10 T 13-10-2018 IPR036590 SOS response associated peptidase-like MADE_1010685 e07ab95a30c9c0df8cfe8d509c8ee83b 248 Pfam PF02586 SOS response associated peptidase (SRAP) 84 217 2.3E-9 T 13-10-2018 IPR003738 SOS response associated peptidase (SRAP) MADE_1010685 e07ab95a30c9c0df8cfe8d509c8ee83b 248 SUPERFAMILY SSF143081 37 192 9.03E-18 T 13-10-2018 IPR036590 SOS response associated peptidase-like MADE_1013800 0f0484351455ee062f4905e2ba6b04e6 360 Gene3D G3DSA:3.40.50.720 5 331 4.1E-137 T 13-10-2018 MADE_1013800 0f0484351455ee062f4905e2ba6b04e6 360 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 332 2.4E-97 T 13-10-2018 IPR016040 NAD(P)-binding domain MADE_1013800 0f0484351455ee062f4905e2ba6b04e6 360 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 346 2.0E-153 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MADE_1013800 0f0484351455ee062f4905e2ba6b04e6 360 SUPERFAMILY SSF51735 1 344 1.15E-96 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013800 0f0484351455ee062f4905e2ba6b04e6 360 Gene3D G3DSA:3.90.25.10 211 340 4.1E-137 T 13-10-2018 MADE_1002760 d45cbc65e21bcf896a497f4ee3c11202 181 SUPERFAMILY SSF53098 4 179 1.44E-49 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1002760 d45cbc65e21bcf896a497f4ee3c11202 181 Pfam PF00929 Exonuclease 9 170 3.3E-35 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1002760 d45cbc65e21bcf896a497f4ee3c11202 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 42.503 T 13-10-2018 IPR022894 Oligoribonuclease GO:0000175 MADE_1002760 d45cbc65e21bcf896a497f4ee3c11202 181 SMART SM00479 7 180 3.4E-22 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1002760 d45cbc65e21bcf896a497f4ee3c11202 181 Gene3D G3DSA:3.30.420.10 1 181 5.4E-74 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 361 507 7.0E-13 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 Gene3D G3DSA:1.10.540.10 123 236 1.0E-99 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 SUPERFAMILY SSF47203 361 516 2.09E-24 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 Pfam PF09317 Domain of unknown function (DUF1974) 515 797 4.6E-112 T 13-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 SUPERFAMILY SSF56645 121 356 3.8E-45 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 139 234 7.5E-17 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 Gene3D G3DSA:1.20.140.10 361 506 1.0E-99 T 13-10-2018 MADE_1010895 8e86cbcd3302b6f26887637c86807708 820 Gene3D G3DSA:2.40.110.10 237 360 1.0E-99 T 13-10-2018 MADE_1013445 27f5efa906e44e83c20049241677ce4d 167 SUPERFAMILY SSF103642 143 163 4.09E-6 T 13-10-2018 MADE_1013445 27f5efa906e44e83c20049241677ce4d 167 Gene3D G3DSA:3.10.450.50 1 165 2.5E-45 T 13-10-2018 MADE_1013445 27f5efa906e44e83c20049241677ce4d 167 SUPERFAMILY SSF54427 23 135 4.6E-27 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1013445 27f5efa906e44e83c20049241677ce4d 167 Pfam PF02810 SEC-C motif 146 163 1.6E-7 T 13-10-2018 IPR004027 SEC-C motif MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 252 285 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 Gene3D G3DSA:3.40.980.10 174 326 4.7E-131 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 175 311 1.2E-27 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 SUPERFAMILY SSF53218 176 320 1.57E-38 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 Gene3D G3DSA:2.40.340.10 327 397 4.7E-131 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 Pfam PF00994 Probable molybdopterin binding domain 179 315 4.2E-20 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 Pfam PF03453 MoeA N-terminal region (domain I and II) 7 166 1.1E-42 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 SUPERFAMILY SSF63867 326 402 6.8E-22 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 SUPERFAMILY SSF63882 6 175 3.4E-49 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 Pfam PF03454 MoeA C-terminal region (domain IV) 331 402 2.2E-18 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 Gene3D G3DSA:2.170.190.11 49 140 4.7E-131 T 13-10-2018 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 Gene3D G3DSA:3.90.105.10 25 173 4.7E-131 T 13-10-2018 MADE_1010945 e9114b6de9c0e2adfe4aed6703f57743 404 SMART SM00852 179 316 1.5E-34 T 13-10-2018 IPR001453 MoaB/Mog domain MADE_1013835 9b4aa41b7f3d888836cbd004d15ba2f4 229 Gene3D G3DSA:3.40.50.300 3 228 1.7E-15 T 13-10-2018 MADE_1013835 9b4aa41b7f3d888836cbd004d15ba2f4 229 SUPERFAMILY SSF52540 34 229 1.84E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013835 9b4aa41b7f3d888836cbd004d15ba2f4 229 Pfam PF00685 Sulfotransferase domain 29 226 9.4E-6 T 13-10-2018 IPR000863 Sulfotransferase domain GO:0008146 MADE_000001022995 60e4ed9349fd1f88b7eccfdb0477eaa9 206 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 115 202 3.4E-28 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MADE_000001022995 60e4ed9349fd1f88b7eccfdb0477eaa9 206 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 4 107 1.8E-25 T 13-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MADE_000001022995 60e4ed9349fd1f88b7eccfdb0477eaa9 206 SUPERFAMILY SSF54534 6 204 3.54E-57 T 13-10-2018 MADE_000001022995 60e4ed9349fd1f88b7eccfdb0477eaa9 206 Gene3D G3DSA:1.10.287.460 3 66 4.9E-20 T 13-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 MADE_000001022995 60e4ed9349fd1f88b7eccfdb0477eaa9 206 Gene3D G3DSA:3.10.50.40 67 205 5.6E-53 T 13-10-2018 MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 Gene3D G3DSA:3.40.50.1000 22 218 4.5E-47 T 13-10-2018 IPR023214 HAD superfamily MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 116 129 2.6E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 163 2.6E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 19 30 2.6E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 165 185 2.6E-5 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 Gene3D G3DSA:1.10.150.240 32 103 4.5E-47 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 SUPERFAMILY SSF56784 20 224 1.55E-43 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 140 202 3.6E-13 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1003580 f421bb417b633b6ad348c818dcd68cd3 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 22 202 1.4E-29 T 13-10-2018 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 Gene3D G3DSA:3.30.360.10 126 233 6.0E-96 T 13-10-2018 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 SUPERFAMILY SSF55347 126 235 2.83E-34 T 13-10-2018 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 149 166 - T 13-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 SUPERFAMILY SSF51735 1 265 6.29E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1007085 a60f23177e641fa5af46545397f661ca 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 264 33.523 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 124 2.8E-34 T 13-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 263 6.1E-87 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 Gene3D G3DSA:3.40.50.720 2 263 6.0E-96 T 13-10-2018 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 PIRSF PIRSF000161 1 267 2.2E-84 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1007085 a60f23177e641fa5af46545397f661ca 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 127 263 3.7E-42 T 13-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 MADE_1000625 f193aa179b7fe1ab3d6748bb0cba6cfd 202 SUPERFAMILY SSF53335 5 179 1.92E-27 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1000625 f193aa179b7fe1ab3d6748bb0cba6cfd 202 Pfam PF08241 Methyltransferase domain 44 141 9.7E-13 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MADE_1000625 f193aa179b7fe1ab3d6748bb0cba6cfd 202 Gene3D G3DSA:3.40.50.150 2 182 5.1E-30 T 13-10-2018 MADE_1004415 3c533216aa75f35f83173f805df1c741 325 Pfam PF00582 Universal stress protein family 178 314 4.0E-12 T 13-10-2018 IPR006016 UspA MADE_1004415 3c533216aa75f35f83173f805df1c741 325 Pfam PF00582 Universal stress protein family 4 142 2.3E-12 T 13-10-2018 IPR006016 UspA MADE_1004415 3c533216aa75f35f83173f805df1c741 325 SUPERFAMILY SSF52402 150 321 1.51E-19 T 13-10-2018 MADE_1004415 3c533216aa75f35f83173f805df1c741 325 Gene3D G3DSA:3.40.50.12370 1 325 1.5E-83 T 13-10-2018 MADE_1004415 3c533216aa75f35f83173f805df1c741 325 SUPERFAMILY SSF52402 4 143 5.36E-18 T 13-10-2018 MADE_1007495 88e5a024f6998268342bafd8bb440510 382 Gene3D G3DSA:3.40.50.2000 5 367 3.1E-88 T 13-10-2018 MADE_1007495 88e5a024f6998268342bafd8bb440510 382 Pfam PF13439 Glycosyltransferase Family 4 16 181 6.4E-12 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1007495 88e5a024f6998268342bafd8bb440510 382 Gene3D G3DSA:3.40.50.2000 179 366 3.1E-88 T 13-10-2018 MADE_1007495 88e5a024f6998268342bafd8bb440510 382 Pfam PF00534 Glycosyl transferases group 1 190 347 6.3E-39 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1007495 88e5a024f6998268342bafd8bb440510 382 SUPERFAMILY SSF53756 1 379 6.28E-71 T 13-10-2018 MADE_000001021000 a08e4d4fb12a6d2e4ef460950043db97 1236 Pfam PF12128 Protein of unknown function (DUF3584) 8 1202 0.0 T 13-10-2018 IPR021979 Protein of unknown function DUF3584 MADE_1006910 943284c53688651fab8fce3d1be6a8e0 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 1.7E-68 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 MADE_1006910 943284c53688651fab8fce3d1be6a8e0 206 SUPERFAMILY SSF55821 1 204 7.32E-62 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MADE_1006910 943284c53688651fab8fce3d1be6a8e0 206 Gene3D G3DSA:3.90.870.10 1 205 1.4E-65 T 13-10-2018 MADE_1006910 943284c53688651fab8fce3d1be6a8e0 206 Pfam PF01300 Telomere recombination 22 198 5.2E-46 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 MADE_1001335 473ac3888df1dfa5c934264cbf5e3870 185 SUPERFAMILY SSF158710 38 182 8.24E-46 T 13-10-2018 IPR023153 PSPTO4464-like domain superfamily MADE_1001335 473ac3888df1dfa5c934264cbf5e3870 185 Pfam PF04751 Protein of unknown function (DUF615) 28 179 3.6E-50 T 13-10-2018 IPR006839 Ribosome-associated, YjgA MADE_1001335 473ac3888df1dfa5c934264cbf5e3870 185 PIRSF PIRSF016183 12 185 3.0E-59 T 13-10-2018 IPR006839 Ribosome-associated, YjgA MADE_1001335 473ac3888df1dfa5c934264cbf5e3870 185 Gene3D G3DSA:1.10.60.30 114 185 3.4E-24 T 13-10-2018 MADE_1001335 473ac3888df1dfa5c934264cbf5e3870 185 Gene3D G3DSA:1.10.60.30 37 113 2.3E-19 T 13-10-2018 MADE_000001023115 fdebcb0d28e21004a19848e9baa2c53b 343 SUPERFAMILY SSF53187 21 316 2.65E-74 T 13-10-2018 MADE_000001023115 fdebcb0d28e21004a19848e9baa2c53b 343 Gene3D G3DSA:3.40.630.10 17 318 3.9E-90 T 13-10-2018 MADE_000001023115 fdebcb0d28e21004a19848e9baa2c53b 343 PIRSF PIRSF039012 3 323 2.0E-88 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MADE_000001023115 fdebcb0d28e21004a19848e9baa2c53b 343 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 46 315 1.3E-58 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MADE_1009445 7f3a7133543a53e017bff2e4db11bca5 258 SUPERFAMILY SSF69572 4 257 5.23E-66 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MADE_1009445 7f3a7133543a53e017bff2e4db11bca5 258 Gene3D G3DSA:3.40.50.720 2 258 4.8E-102 T 13-10-2018 MADE_1009445 7f3a7133543a53e017bff2e4db11bca5 258 Pfam PF00899 ThiF family 15 256 2.2E-39 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MADE_1000935 306affd254a85c6ded1e1bf8042759f6 290 Gene3D G3DSA:3.40.50.20 40 82 4.2E-12 T 13-10-2018 MADE_1000935 306affd254a85c6ded1e1bf8042759f6 290 Gene3D G3DSA:3.30.470.20 83 231 4.2E-12 T 13-10-2018 MADE_1000935 306affd254a85c6ded1e1bf8042759f6 290 SUPERFAMILY SSF56059 93 287 1.59E-16 T 13-10-2018 MADE_1000935 306affd254a85c6ded1e1bf8042759f6 290 Gene3D G3DSA:3.30.1490.20 108 175 4.2E-12 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1000935 306affd254a85c6ded1e1bf8042759f6 290 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 231 5.3E-6 T 13-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 MADE_1008525 9dbceca50df19021b48e98fd3572e8dd 450 Gene3D G3DSA:1.10.10.60 345 449 2.2E-13 T 13-10-2018 MADE_1008525 9dbceca50df19021b48e98fd3572e8dd 450 Pfam PF12833 Helix-turn-helix domain 370 446 3.3E-10 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1008525 9dbceca50df19021b48e98fd3572e8dd 450 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 132 316 2.6E-13 T 13-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal MADE_1008525 9dbceca50df19021b48e98fd3572e8dd 450 SMART SM00342 364 446 1.1E-10 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1012375 a08740b75e84a185ec902ab674763cf5 239 Pfam PF00106 short chain dehydrogenase 2 179 5.7E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012375 a08740b75e84a185ec902ab674763cf5 239 SUPERFAMILY SSF51735 2 232 2.42E-55 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1012375 a08740b75e84a185ec902ab674763cf5 239 Gene3D G3DSA:3.40.50.720 1 238 2.4E-57 T 13-10-2018 MADE_1012375 a08740b75e84a185ec902ab674763cf5 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 3.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012375 a08740b75e84a185ec902ab674763cf5 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 3.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012375 a08740b75e84a185ec902ab674763cf5 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012375 a08740b75e84a185ec902ab674763cf5 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 3.3E-19 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1011685 11f2ea2a9ff6feac0288eae0ca08f176 214 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 210 1.9E-81 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MADE_1011685 11f2ea2a9ff6feac0288eae0ca08f176 214 SUPERFAMILY SSF51569 7 210 1.3E-70 T 13-10-2018 MADE_1011685 11f2ea2a9ff6feac0288eae0ca08f176 214 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 41 50 - T 13-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MADE_1011685 11f2ea2a9ff6feac0288eae0ca08f176 214 Gene3D G3DSA:3.20.20.70 1 213 1.5E-74 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1011685 11f2ea2a9ff6feac0288eae0ca08f176 214 Pfam PF01081 KDPG and KHG aldolase 11 204 1.0E-80 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MADE_1011685 11f2ea2a9ff6feac0288eae0ca08f176 214 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 129 142 - T 13-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 Pfam PF00107 Zinc-binding dehydrogenase 174 301 2.6E-28 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 Gene3D G3DSA:3.40.50.720 153 286 3.0E-119 T 13-10-2018 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 SMART SM00829 12 338 2.5E-4 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 5.8E-32 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 60.252 T 13-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 Gene3D G3DSA:3.90.180.10 20 328 3.0E-119 T 13-10-2018 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 SUPERFAMILY SSF50129 1 173 2.13E-52 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 SUPERFAMILY SSF51735 141 305 6.12E-38 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MADE_1000320 233028a7f4f237e57df4760e6f19f99f 341 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 4 340 5.1E-174 T 13-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 MADE_1000710 798dddb257d974b5da550e450047be33 259 SUPERFAMILY SSF69572 8 257 1.57E-63 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MADE_1000710 798dddb257d974b5da550e450047be33 259 Pfam PF00899 ThiF family 18 237 1.4E-46 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MADE_1000710 798dddb257d974b5da550e450047be33 259 Gene3D G3DSA:3.40.50.720 10 259 1.3E-66 T 13-10-2018 MADE_1008910 430585ad12f07d341cb7919c064f86b3 152 SUPERFAMILY SSF75420 3 83 3.4E-28 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily MADE_1008910 430585ad12f07d341cb7919c064f86b3 152 SUPERFAMILY SSF74942 84 151 1.96E-16 T 13-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily MADE_1008910 430585ad12f07d341cb7919c064f86b3 152 Pfam PF02576 RimP N-terminal domain 11 83 8.7E-32 T 13-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal MADE_1008910 430585ad12f07d341cb7919c064f86b3 152 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 151 25.082 T 13-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 MADE_1008910 430585ad12f07d341cb7919c064f86b3 152 Pfam PF17384 RimP C-terminal SH3 domain 86 151 1.1E-15 T 13-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal MADE_1008910 430585ad12f07d341cb7919c064f86b3 152 Gene3D G3DSA:3.30.300.70 1 80 6.2E-30 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 405 518 3.3E-25 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 Pfam PF00512 His Kinase A (phospho-acceptor) domain 294 356 9.9E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 Gene3D G3DSA:3.30.450.20 154 267 1.7E-11 T 13-10-2018 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 Gene3D G3DSA:3.30.565.10 357 523 3.3E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 SUPERFAMILY SSF52172 542 662 6.4E-32 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 6.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 6.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 6.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 6.1E-15 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 SUPERFAMILY SSF55785 147 270 2.3E-7 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 SUPERFAMILY SSF47384 278 355 5.1E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 SMART SM00388 293 358 1.0E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 SMART SM00387 405 520 1.1E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 SMART SM00448 542 656 8.1E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 Gene3D G3DSA:3.40.50.12740 542 667 1.5E-35 T 13-10-2018 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 Pfam PF00072 Response regulator receiver domain 544 656 1.2E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 SUPERFAMILY SSF55874 347 519 2.49E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1007990 59ce5e88bb2a75d9a1d4afbf1b74ac58 667 Gene3D G3DSA:1.10.287.130 268 355 2.1E-18 T 13-10-2018 MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 Gene3D G3DSA:2.60.40.10 847 918 1.1E-13 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 Gene3D G3DSA:2.60.120.560 10 169 2.0E-16 T 13-10-2018 MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 Gene3D G3DSA:2.60.40.10 750 839 2.4E-8 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 SMART SM00089 921 1015 0.45 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 SMART SM00089 760 841 0.21 T 13-10-2018 IPR022409 PKD/Chitinase domain MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 SUPERFAMILY SSF49299 758 839 1.01E-6 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 Pfam PF16403 Domain of unknown function (DUF5011) 849 917 4.3E-10 T 13-10-2018 IPR032179 Domain of unknown function DUF5011 MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 SUPERFAMILY SSF49299 922 1015 2.55E-6 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 Gene3D G3DSA:2.60.40.10 919 1016 1.8E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1014530 191006d13ec364a8a584dcb748ffa647 1098 SUPERFAMILY SSF49299 806 919 2.49E-8 T 13-10-2018 IPR035986 PKD domain superfamily MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 PRINTS PR01438 Universal stress protein signature 275 297 2.9E-7 T 13-10-2018 IPR006015 Universal stress protein A MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 PRINTS PR01438 Universal stress protein signature 257 269 2.9E-7 T 13-10-2018 IPR006015 Universal stress protein A MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 PRINTS PR01438 Universal stress protein signature 4 22 2.9E-7 T 13-10-2018 IPR006015 Universal stress protein A MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 Gene3D G3DSA:3.40.50.12370 1 307 2.0E-106 T 13-10-2018 MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 SUPERFAMILY SSF52402 154 304 8.04E-21 T 13-10-2018 MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 SUPERFAMILY SSF52402 5 155 1.42E-24 T 13-10-2018 MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 Pfam PF00582 Universal stress protein family 181 297 2.1E-14 T 13-10-2018 IPR006016 UspA MADE_1010465 87ad6ec5b08b0bb660cf34aac7f67763 307 Pfam PF00582 Universal stress protein family 5 144 1.5E-16 T 13-10-2018 IPR006016 UspA MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 Pfam PF00106 short chain dehydrogenase 3 199 6.5E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.3E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.3E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.3E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.3E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.3E-24 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 SUPERFAMILY SSF51735 2 260 8.86E-63 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 Gene3D G3DSA:3.40.50.720 1 272 5.4E-71 T 13-10-2018 MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1012695 4852741cf262f2aaf72ef09ba8472177 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.7E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014220 41105f19ec343dc8fbc4b5ff18b4d433 146 Gene3D G3DSA:3.30.530.20 2 114 6.9E-17 T 13-10-2018 IPR023393 START-like domain superfamily MADE_1014220 41105f19ec343dc8fbc4b5ff18b4d433 146 SUPERFAMILY SSF55961 3 142 2.16E-17 T 13-10-2018 MADE_1014220 41105f19ec343dc8fbc4b5ff18b4d433 146 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 112 1.8E-12 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase MADE_1010325 f1d5102504a6fbe2f218444438c659aa 454 Pfam PF12487 Protein of unknown function (DUF3703) 5 111 3.7E-36 T 13-10-2018 IPR022172 Protein of unknown function DUF3703 MADE_1010325 f1d5102504a6fbe2f218444438c659aa 454 Gene3D G3DSA:3.60.15.10 164 444 4.4E-35 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1010325 f1d5102504a6fbe2f218444438c659aa 454 SUPERFAMILY SSF56281 181 362 9.6E-17 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1010325 f1d5102504a6fbe2f218444438c659aa 454 Pfam PF00753 Metallo-beta-lactamase superfamily 192 249 3.0E-9 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1016675 1e2227674970ad0526ce623ccc6b46c4 579 SUPERFAMILY SSF56801 27 568 9.94E-154 T 13-10-2018 MADE_1016675 1e2227674970ad0526ce623ccc6b46c4 579 Gene3D G3DSA:3.30.300.30 468 571 1.3E-30 T 13-10-2018 MADE_1016675 1e2227674970ad0526ce623ccc6b46c4 579 Gene3D G3DSA:3.40.50.12780 26 467 8.0E-119 T 13-10-2018 MADE_1016675 1e2227674970ad0526ce623ccc6b46c4 579 Pfam PF00501 AMP-binding enzyme 36 472 1.8E-109 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_1016675 1e2227674970ad0526ce623ccc6b46c4 579 Pfam PF13193 AMP-binding enzyme C-terminal domain 481 556 9.6E-15 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MADE_1016675 1e2227674970ad0526ce623ccc6b46c4 579 ProSitePatterns PS00455 Putative AMP-binding domain signature. 222 233 - T 13-10-2018 IPR020845 AMP-binding, conserved site MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 13-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 160 1.8E-50 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 289 6.4E-36 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 289 1.2E-123 T 13-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 SUPERFAMILY SSF51735 3 161 7.63E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 Gene3D G3DSA:1.10.1040.10 162 291 3.1E-40 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 SUPERFAMILY SSF48179 161 290 4.08E-39 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 Gene3D G3DSA:3.40.50.720 2 161 2.2E-55 T 13-10-2018 MADE_1016370 76a8ce16308b54e5de29a48c3c9b7b4d 291 PIRSF PIRSF000103 1 291 4.6E-78 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 Pfam PF00677 Lumazine binding domain 100 184 1.9E-24 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 Pfam PF00677 Lumazine binding domain 3 87 3.4E-20 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 SUPERFAMILY SSF63380 93 194 5.02E-34 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 4.5E-68 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 Gene3D G3DSA:2.40.30.20 1 89 4.9E-26 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 Gene3D G3DSA:2.40.30.20 102 204 3.0E-36 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 PIRSF PIRSF000498 1 212 3.0E-78 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 MADE_1012445 d626ab1607b3cc0532897b4070cb7121 220 SUPERFAMILY SSF63380 1 93 3.57E-26 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_1016290 e987b930a508fafb148aa208d85acfa0 624 Gene3D G3DSA:2.40.170.20 148 623 1.5E-22 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1016290 e987b930a508fafb148aa208d85acfa0 624 SUPERFAMILY SSF56935 48 622 5.16E-37 T 13-10-2018 MADE_1004330 25f0246b63a0238e7d020ff8b6049b80 167 SUPERFAMILY SSF53098 9 161 4.86E-16 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1004330 25f0246b63a0238e7d020ff8b6049b80 167 Gene3D G3DSA:3.30.420.10 8 165 9.1E-14 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1004330 25f0246b63a0238e7d020ff8b6049b80 167 Pfam PF00929 Exonuclease 9 154 6.5E-6 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 Gene3D G3DSA:2.120.10.90 504 756 3.3E-8 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 471 2.7E-132 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 SMART SM00434 15 465 1.7E-226 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 Gene3D G3DSA:3.90.199.10 34 165 5.1E-60 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 SUPERFAMILY SSF101904 501 749 1.16E-47 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 Gene3D G3DSA:1.10.268.10 348 487 1.2E-46 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 SUPERFAMILY SSF56719 35 487 7.59E-153 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 12 746 0.0 T 13-10-2018 MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 Gene3D G3DSA:3.30.1360.40 166 347 5.7E-66 T 13-10-2018 MADE_1002480 ac99b5b209ff40959fd53179c5a802d2 761 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 8 747 33.287 T 13-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 MADE_1010515 1d3dc76e68f448c6893b9928ad5537a9 166 Gene3D G3DSA:3.40.30.10 1 166 1.8E-48 T 13-10-2018 MADE_1010515 1d3dc76e68f448c6893b9928ad5537a9 166 SUPERFAMILY SSF52833 1 162 1.1E-44 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1010515 1d3dc76e68f448c6893b9928ad5537a9 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 13-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 MADE_1010515 1d3dc76e68f448c6893b9928ad5537a9 166 Pfam PF08534 Redoxin 20 161 5.8E-29 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MADE_1010515 1d3dc76e68f448c6893b9928ad5537a9 166 Hamap MF_00269 Thiol peroxidase [tpx]. 3 165 38.238 T 13-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 MADE_1013585 5398db6469561152942b984c0a0d239a 87 Pfam PF07498 Rho termination factor, N-terminal domain 58 84 1.4E-7 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 MADE_1013585 5398db6469561152942b984c0a0d239a 87 SUPERFAMILY SSF68912 50 84 2.2E-5 T 13-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 Gene3D G3DSA:1.20.120.430 126 462 3.4E-106 T 13-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 462 1.8E-108 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 Gene3D G3DSA:3.30.1360.120 1 125 3.0E-39 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 SUPERFAMILY SSF52540 76 381 1.14E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 9 462 32.874 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 Pfam PF01926 50S ribosome-binding GTPase 222 340 2.6E-25 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 SUPERFAMILY SSF116878 125 462 3.01E-50 T 13-10-2018 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 PRINTS PR00449 Transforming protein P21 ras signature 330 343 1.3E-5 T 13-10-2018 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 PRINTS PR00449 Transforming protein P21 ras signature 362 384 1.3E-5 T 13-10-2018 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 PRINTS PR00449 Transforming protein P21 ras signature 221 242 1.3E-5 T 13-10-2018 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 Pfam PF12631 MnmE helical domain 127 459 1.5E-60 T 13-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 Gene3D G3DSA:3.40.50.300 221 390 3.4E-106 T 13-10-2018 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 220 376 1.9E-24 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1020530 6eb2f40761666c463bc5f17fdde89102 462 Pfam PF10396 GTP-binding protein TrmE N-terminus 10 124 1.1E-35 T 13-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 MADE_1010885 9f5addac48302e97629871cc4fa20225 216 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 7 195 2.0E-73 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MADE_1010885 9f5addac48302e97629871cc4fa20225 216 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 7 192 31.787 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 MADE_1010885 9f5addac48302e97629871cc4fa20225 216 Pfam PF00551 Formyl transferase 7 186 4.5E-60 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1010885 9f5addac48302e97629871cc4fa20225 216 Gene3D G3DSA:3.40.50.170 6 216 6.5E-86 T 13-10-2018 MADE_1010885 9f5addac48302e97629871cc4fa20225 216 SUPERFAMILY SSF53328 7 206 1.44E-68 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1005675 e1663b9a77d36781d848901ff1ff5038 161 Pfam PF02169 LPP20 lipoprotein 43 138 6.3E-13 T 13-10-2018 IPR024952 Lipoprotein LPP20-like MADE_1005675 e1663b9a77d36781d848901ff1ff5038 161 PIRSF PIRSF028687 8 161 3.2E-47 T 13-10-2018 IPR007293 Flagellar protein FlgP MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Gene3D G3DSA:2.30.30.140 5 57 5.1E-21 T 13-10-2018 MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 SUPERFAMILY SSF52540 146 384 1.24E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Gene3D G3DSA:3.40.50.300 432 620 4.8E-40 T 13-10-2018 MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 SUPERFAMILY SSF52540 282 630 1.07E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Pfam PF00176 SNF2 family N-terminal domain 176 354 1.4E-17 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Gene3D G3DSA:3.30.360.80 700 772 5.9E-24 T 13-10-2018 MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Pfam PF00271 Helicase conserved C-terminal domain 479 588 7.7E-14 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Gene3D G3DSA:2.30.30.930 59 117 2.3E-19 T 13-10-2018 MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 SMART SM00487 153 355 2.2E-20 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Pfam PF12137 RNA polymerase recycling family C-terminal 592 944 1.7E-118 T 13-10-2018 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 SMART SM00490 504 588 9.8E-15 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Gene3D G3DSA:3.40.50.10810 153 431 4.2E-90 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily MADE_1003495 db7ba8c1cf9aa87a73c2e6b2a8f188f6 947 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 5 946 27.592 T 13-10-2018 IPR023949 RNA polymerase-associated protein RapA GO:0006355 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 Pfam PF12404 Peptidase 5 79 1.3E-22 T 13-10-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 PIRSF PIRSF036388 1 427 3.4E-176 T 13-10-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 Gene3D G3DSA:3.40.630.10 92 425 9.4E-104 T 13-10-2018 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 SUPERFAMILY SSF53187 102 425 1.13E-98 T 13-10-2018 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 272 279 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 106 418 3.6E-99 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 PRINTS PR00481 Cytosol aminopeptidase signature 209 230 3.4E-46 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 PRINTS PR00481 Cytosol aminopeptidase signature 268 288 3.4E-46 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 PRINTS PR00481 Cytosol aminopeptidase signature 187 204 3.4E-46 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 PRINTS PR00481 Cytosol aminopeptidase signature 246 267 3.4E-46 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1018410 4002255ea3a05dc23a8d8123bb6298bd 427 PRINTS PR00481 Cytosol aminopeptidase signature 296 311 3.4E-46 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 Gene3D G3DSA:3.30.450.20 74 237 5.2E-29 T 13-10-2018 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 Pfam PF02743 Cache domain 50 329 1.0E-18 T 13-10-2018 IPR033479 Double Cache domain 1 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 Gene3D G3DSA:3.30.450.20 61 294 5.2E-29 T 13-10-2018 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 575 604 9.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 357 377 9.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 546 573 9.1E-20 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 Gene3D G3DSA:1.10.287.950 378 710 2.8E-65 T 13-10-2018 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 SMART SM00283 448 709 3.8E-60 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 SUPERFAMILY SSF58104 401 710 7.98E-67 T 13-10-2018 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 Pfam PF00672 HAMP domain 379 429 1.9E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 512 671 2.6E-43 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 SMART SM00304 468 528 88.0 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1013230 c1fd5077ba6935b1a49d82e88a649f1a 712 SMART SM00304 379 433 1.5E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1009615 938da748d9318d1d480afefbb6ff7a55 253 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 241 2.2E-59 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MADE_1009615 938da748d9318d1d480afefbb6ff7a55 253 SUPERFAMILY SSF102705 6 252 4.58E-79 T 13-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily MADE_1009615 938da748d9318d1d480afefbb6ff7a55 253 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 3 252 3.8E-66 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 MADE_1009615 938da748d9318d1d480afefbb6ff7a55 253 Gene3D G3DSA:3.40.1390.30 16 238 7.5E-81 T 13-10-2018 MADE_1009615 938da748d9318d1d480afefbb6ff7a55 253 Gene3D G3DSA:3.40.1390.30 99 224 7.5E-81 T 13-10-2018 MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 Gene3D G3DSA:1.20.1260.10 3 169 9.0E-51 T 13-10-2018 IPR012347 Ferritin-like MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 SUPERFAMILY SSF47240 4 161 5.28E-41 T 13-10-2018 IPR009078 Ferritin-like superfamily MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 Pfam PF00210 Ferritin-like domain 22 161 6.6E-26 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 43 59 5.1E-13 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 67 83 5.1E-13 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 138 156 5.1E-13 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 ProSitePatterns PS00818 Dps protein family signature 1. 43 59 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MADE_1006985 14664508610f78c11dc2aa922028e6bb 169 PIRSF PIRSF005900 1 166 1.9E-48 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1007685 81feca81f7d8da01a12babd38274f861 226 SUPERFAMILY SSF53474 19 222 3.6E-23 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1007685 81feca81f7d8da01a12babd38274f861 226 Pfam PF12146 Serine aminopeptidase, S33 22 137 1.0E-6 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 MADE_1007685 81feca81f7d8da01a12babd38274f861 226 Gene3D G3DSA:3.40.50.1820 25 211 3.4E-27 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1011755 26bdaa8ff3b7c18bd0ff1f48fb34d6d4 327 SUPERFAMILY SSF53448 4 256 5.18E-23 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1011755 26bdaa8ff3b7c18bd0ff1f48fb34d6d4 327 Gene3D G3DSA:3.90.550.10 1 229 2.5E-17 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1011755 26bdaa8ff3b7c18bd0ff1f48fb34d6d4 327 Pfam PF02709 N-terminal domain of galactosyltransferase 160 223 7.1E-10 T 13-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 MADE_1000795 67c4cb02daac77671e75a3516060c578 157 Gene3D G3DSA:3.40.30.10 2 157 1.2E-56 T 13-10-2018 MADE_1000795 67c4cb02daac77671e75a3516060c578 157 Pfam PF08534 Redoxin 3 154 1.5E-33 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MADE_1000795 67c4cb02daac77671e75a3516060c578 157 SUPERFAMILY SSF52833 1 157 4.63E-36 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 612 722 1.2E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 SUPERFAMILY SSF49344 79 253 1.41E-8 T 13-10-2018 MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 SUPERFAMILY SSF55874 553 722 4.19E-24 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 Pfam PF00512 His Kinase A (phospho-acceptor) domain 500 562 8.3E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 Gene3D G3DSA:2.60.40.1190 83 270 1.3E-10 T 13-10-2018 MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 SMART SM00387 607 722 1.7E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 Gene3D G3DSA:1.10.287.130 440 556 3.4E-16 T 13-10-2018 MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 TIGRFAM TIGR03785 marine_sort_HK: proteobacterial dedicated sortase system histidine kinase 7 721 4.2E-275 T 13-10-2018 IPR022510 Sortase system, histidine kinase MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 SUPERFAMILY SSF47384 482 561 1.18E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 SMART SM00388 498 563 8.8E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018480 7d2fd1b518abcbd07bfb7a871776f3cb 722 Gene3D G3DSA:3.30.565.10 558 722 2.3E-21 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018370 8d9b439f577c68ec42095e8826b138ac 411 Pfam PF00563 EAL domain 75 188 4.6E-10 T 13-10-2018 IPR001633 EAL domain MADE_1018370 8d9b439f577c68ec42095e8826b138ac 411 SUPERFAMILY SSF109604 179 397 2.45E-39 T 13-10-2018 MADE_1018370 8d9b439f577c68ec42095e8826b138ac 411 SUPERFAMILY SSF141868 5 188 4.45E-22 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1018370 8d9b439f577c68ec42095e8826b138ac 411 Pfam PF08668 HDOD domain 196 317 2.4E-10 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD MADE_1018370 8d9b439f577c68ec42095e8826b138ac 411 Gene3D G3DSA:3.20.20.450 59 194 1.1E-13 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1018370 8d9b439f577c68ec42095e8826b138ac 411 PIRSF PIRSF003180 1 402 9.9E-116 T 13-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing MADE_1018370 8d9b439f577c68ec42095e8826b138ac 411 Gene3D G3DSA:1.10.3210.10 195 359 3.6E-19 T 13-10-2018 MADE_1018415 9a31617bc2f91c65cb3e89a4e848a8d1 238 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 237 1.6E-61 T 13-10-2018 IPR005224 Sugar fermentation stimulation protein MADE_1018415 9a31617bc2f91c65cb3e89a4e848a8d1 238 Pfam PF03749 Sugar fermentation stimulation protein 13 228 1.6E-70 T 13-10-2018 IPR005224 Sugar fermentation stimulation protein MADE_1018415 9a31617bc2f91c65cb3e89a4e848a8d1 238 Gene3D G3DSA:3.40.1350.60 81 238 2.5E-48 T 13-10-2018 MADE_1018415 9a31617bc2f91c65cb3e89a4e848a8d1 238 Gene3D G3DSA:2.40.50.580 1 80 2.5E-31 T 13-10-2018 MADE_1018415 9a31617bc2f91c65cb3e89a4e848a8d1 238 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 238 54.12 T 13-10-2018 IPR005224 Sugar fermentation stimulation protein MADE_1006570 850bb2f01303a02db3b60266440abd6d 210 Pfam PF04542 Sigma-70 region 2 36 97 3.2E-7 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1006570 850bb2f01303a02db3b60266440abd6d 210 Gene3D G3DSA:1.10.1740.10 17 109 8.4E-9 T 13-10-2018 MADE_1006570 850bb2f01303a02db3b60266440abd6d 210 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 185 9.1E-20 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1006570 850bb2f01303a02db3b60266440abd6d 210 Pfam PF08281 Sigma-70, region 4 136 183 4.6E-12 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1006570 850bb2f01303a02db3b60266440abd6d 210 SUPERFAMILY SSF88946 31 110 6.28E-10 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1006570 850bb2f01303a02db3b60266440abd6d 210 Gene3D G3DSA:1.10.10.10 114 191 5.1E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006570 850bb2f01303a02db3b60266440abd6d 210 SUPERFAMILY SSF88659 124 187 3.49E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1007980 d1a813472fb649d6bfc0fcf99ded453a 72 Pfam PF00563 EAL domain 2 55 3.7E-14 T 13-10-2018 IPR001633 EAL domain MADE_1007980 d1a813472fb649d6bfc0fcf99ded453a 72 SUPERFAMILY SSF141868 2 66 7.59E-18 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007980 d1a813472fb649d6bfc0fcf99ded453a 72 Gene3D G3DSA:3.20.20.450 1 71 3.2E-19 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1008425 7312d3ea797f9ff2024b49412fb56eb6 298 Pfam PF00682 HMGL-like 5 279 9.7E-55 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 MADE_1008425 7312d3ea797f9ff2024b49412fb56eb6 298 Gene3D G3DSA:3.20.20.70 1 298 2.1E-132 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1008425 7312d3ea797f9ff2024b49412fb56eb6 298 SUPERFAMILY SSF51569 2 292 5.71E-72 T 13-10-2018 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 SUPERFAMILY SSF50156 251 348 2.23E-20 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 Pfam PF13365 Trypsin-like peptidase domain 91 223 1.9E-26 T 13-10-2018 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 SUPERFAMILY SSF50494 48 273 1.32E-52 T 13-10-2018 IPR009003 Peptidase S1, PA clan MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 Gene3D G3DSA:2.40.10.10 40 150 4.8E-27 T 13-10-2018 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 Pfam PF13180 PDZ domain 270 348 1.8E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 Gene3D G3DSA:2.40.10.10 154 269 7.1E-31 T 13-10-2018 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 SMART SM00228 268 340 3.2E-13 T 13-10-2018 IPR001478 PDZ domain GO:0005515 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 Gene3D G3DSA:2.30.42.10 270 354 1.2E-19 T 13-10-2018 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 PRINTS PR00834 HtrA/DegQ protease family signature 298 310 8.6E-44 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 PRINTS PR00834 HtrA/DegQ protease family signature 216 233 8.6E-44 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 PRINTS PR00834 HtrA/DegQ protease family signature 121 141 8.6E-44 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 PRINTS PR00834 HtrA/DegQ protease family signature 194 211 8.6E-44 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 PRINTS PR00834 HtrA/DegQ protease family signature 100 112 8.6E-44 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1004255 f24eb398bb8eb18eddd08daf4d468d11 356 PRINTS PR00834 HtrA/DegQ protease family signature 161 185 8.6E-44 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 MADE_1003730 571278ee9810277dc52d7e2ba08c0021 331 SUPERFAMILY SSF161098 115 314 2.35E-23 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1003730 571278ee9810277dc52d7e2ba08c0021 331 Gene3D G3DSA:1.10.3720.10 114 321 2.8E-22 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1003730 571278ee9810277dc52d7e2ba08c0021 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 139 322 1.5E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1014250 8445b87f4ff6f888603bf2e5d424ddf1 394 Pfam PF07995 Glucose / Sorbosone dehydrogenase 56 391 9.8E-122 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase MADE_1014250 8445b87f4ff6f888603bf2e5d424ddf1 394 Gene3D G3DSA:2.120.10.30 46 394 1.7E-102 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1014250 8445b87f4ff6f888603bf2e5d424ddf1 394 SUPERFAMILY SSF50952 44 383 9.94E-40 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MADE_1002660 3dc248856c477cfcf655033244c00196 267 Pfam PF00696 Amino acid kinase family 6 235 2.2E-39 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MADE_1002660 3dc248856c477cfcf655033244c00196 267 SUPERFAMILY SSF53633 5 254 1.13E-54 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1002660 3dc248856c477cfcf655033244c00196 267 PIRSF PIRSF000728 1 258 3.6E-63 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_1002660 3dc248856c477cfcf655033244c00196 267 Gene3D G3DSA:3.40.1160.10 2 253 3.7E-61 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1002660 3dc248856c477cfcf655033244c00196 267 TIGRFAM TIGR00761 argB: acetylglutamate kinase 6 233 1.6E-57 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_1002660 3dc248856c477cfcf655033244c00196 267 Hamap MF_00082 Acetylglutamate kinase [argB]. 3 251 40.285 T 13-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_000001023655 10bffbd369eff86f1bdc58bd5346bcce 264 Gene3D G3DSA:3.20.70.20 12 240 1.6E-17 T 13-10-2018 MADE_000001023655 10bffbd369eff86f1bdc58bd5346bcce 264 SUPERFAMILY SSF51998 10 241 1.01E-45 T 13-10-2018 MADE_000001023655 10bffbd369eff86f1bdc58bd5346bcce 264 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 11 257 1.4E-53 T 13-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 MADE_1015855 0664f18b18d4cff8e908b2ce6ec5d31a 400 Gene3D G3DSA:3.30.420.40 154 359 3.4E-124 T 13-10-2018 MADE_1015855 0664f18b18d4cff8e908b2ce6ec5d31a 400 Gene3D G3DSA:3.30.420.40 9 394 3.4E-124 T 13-10-2018 MADE_1015855 0664f18b18d4cff8e908b2ce6ec5d31a 400 SUPERFAMILY SSF53067 3 370 5.96E-23 T 13-10-2018 MADE_1015855 0664f18b18d4cff8e908b2ce6ec5d31a 400 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 3 398 3.7E-134 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MADE_1015855 0664f18b18d4cff8e908b2ce6ec5d31a 400 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 2 399 39.667 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 MADE_1013460 b3e3eb7d4ee6e60fcc386ec85fec5f01 324 SMART SM00829 10 322 1.8E-40 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1013460 b3e3eb7d4ee6e60fcc386ec85fec5f01 324 SUPERFAMILY SSF50129 1 140 4.87E-40 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1013460 b3e3eb7d4ee6e60fcc386ec85fec5f01 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 6.6E-11 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1013460 b3e3eb7d4ee6e60fcc386ec85fec5f01 324 SUPERFAMILY SSF51735 116 288 2.03E-52 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013460 b3e3eb7d4ee6e60fcc386ec85fec5f01 324 Pfam PF00107 Zinc-binding dehydrogenase 151 282 1.9E-35 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1013460 b3e3eb7d4ee6e60fcc386ec85fec5f01 324 Gene3D G3DSA:3.40.50.720 123 267 3.0E-102 T 13-10-2018 MADE_1013460 b3e3eb7d4ee6e60fcc386ec85fec5f01 324 Gene3D G3DSA:3.90.180.10 13 318 3.0E-102 T 13-10-2018 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 SUPERFAMILY SSF55785 20 112 9.07E-25 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 SMART SM00283 259 520 1.4E-62 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 Gene3D G3DSA:1.10.287.950 232 526 8.3E-62 T 13-10-2018 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 105 3.7E-13 T 13-10-2018 IPR000014 PAS domain MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 Gene3D G3DSA:3.30.450.20 7 116 3.0E-23 T 13-10-2018 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 Pfam PF08447 PAS fold 32 105 3.4E-14 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 280 309 7.2E-22 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 357 384 7.2E-22 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 415 7.2E-22 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 318 485 2.3E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1018975 663228940b322211bb2c2df0980e3bf8 527 SUPERFAMILY SSF58104 257 521 8.76E-62 T 13-10-2018 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 340 365 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 372 388 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 502 530 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 439 464 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 400 420 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 263 284 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 228 255 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 PRINTS PR00791 Peptidyl-dipeptidase A (M2) metalloprotease family signature 474 501 2.7E-79 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 Gene3D G3DSA:1.10.1370.30 347 602 9.5E-6 T 13-10-2018 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 SUPERFAMILY SSF55486 35 606 1.39E-205 T 13-10-2018 MADE_1008755 b1e154c2eb01e7d7344a9cccad5848c9 606 Pfam PF01401 Angiotensin-converting enzyme 35 606 1.7E-210 T 13-10-2018 IPR001548 Peptidase M2, peptidyl-dipeptidase A GO:0006508|GO:0008237|GO:0008241|GO:0016020 MADE_1003795 1aaa7d8d68ed3d80d96f0398b38a78d3 200 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 184 2.4E-46 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MADE_1003795 1aaa7d8d68ed3d80d96f0398b38a78d3 200 SMART SM01207 10 185 1.1E-76 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MADE_1003795 1aaa7d8d68ed3d80d96f0398b38a78d3 200 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 193 18.868 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MADE_1003795 1aaa7d8d68ed3d80d96f0398b38a78d3 200 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 195 1.7E-65 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 MADE_1019135 afd2da8e86d58d43c3982f109926d53e 63 Pfam PF05532 CsbD-like 4 56 2.2E-21 T 13-10-2018 IPR008462 CsbD-like domain MADE_1019135 afd2da8e86d58d43c3982f109926d53e 63 Gene3D G3DSA:1.10.1470.10 1 63 7.6E-31 T 13-10-2018 IPR036629 YjbJ superfamily MADE_1019135 afd2da8e86d58d43c3982f109926d53e 63 PIRSF PIRSF039008 1 63 1.5E-31 T 13-10-2018 IPR026042 Stress response protein YjbJ MADE_1019135 afd2da8e86d58d43c3982f109926d53e 63 SUPERFAMILY SSF69047 1 62 2.75E-25 T 13-10-2018 IPR036629 YjbJ superfamily MADE_000001023595 6cca22477a0b65d88ccf9d986d184a8b 277 Pfam PF00293 NUDIX domain 153 255 6.4E-19 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MADE_000001023595 6cca22477a0b65d88ccf9d986d184a8b 277 Gene3D G3DSA:3.90.79.20 2 146 3.5E-26 T 13-10-2018 MADE_000001023595 6cca22477a0b65d88ccf9d986d184a8b 277 SUPERFAMILY SSF55811 100 256 2.03E-40 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_000001023595 6cca22477a0b65d88ccf9d986d184a8b 277 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 114 145 1.1E-12 T 13-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 MADE_000001023595 6cca22477a0b65d88ccf9d986d184a8b 277 SUPERFAMILY SSF55811 11 117 2.34E-11 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_000001023595 6cca22477a0b65d88ccf9d986d184a8b 277 Gene3D G3DSA:3.90.79.10 147 276 1.2E-40 T 13-10-2018 MADE_000001023595 6cca22477a0b65d88ccf9d986d184a8b 277 ProSitePatterns PS00893 Nudix box signature. 181 202 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MADE_1020525 bbf011a4a3fea642f5fa769617cfd598 145 SUPERFAMILY SSF52218 5 142 1.48E-37 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1020525 bbf011a4a3fea642f5fa769617cfd598 145 Pfam PF00258 Flavodoxin 7 137 9.0E-21 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MADE_1020525 bbf011a4a3fea642f5fa769617cfd598 145 Gene3D G3DSA:3.40.50.360 3 144 1.5E-39 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1000230 223504e96a719f5d52dc180212c7b8a0 407 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 399 9.7E-147 T 13-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 MADE_1000230 223504e96a719f5d52dc180212c7b8a0 407 Gene3D G3DSA:3.40.50.1950 1 188 8.8E-63 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MADE_1000230 223504e96a719f5d52dc180212c7b8a0 407 Pfam PF02441 Flavoprotein 6 174 1.5E-48 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MADE_1000230 223504e96a719f5d52dc180212c7b8a0 407 SUPERFAMILY SSF52507 4 175 2.62E-63 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MADE_1000230 223504e96a719f5d52dc180212c7b8a0 407 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 194 375 3.0E-71 T 13-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MADE_1000230 223504e96a719f5d52dc180212c7b8a0 407 Gene3D G3DSA:3.40.50.10300 189 407 3.1E-79 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MADE_1000230 223504e96a719f5d52dc180212c7b8a0 407 SUPERFAMILY SSF102645 192 403 2.62E-77 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 MADE_1004625 28d90d422d2a87ef751beb58f351351a 236 Pfam PF04172 LrgB-like family 20 232 3.5E-64 T 13-10-2018 IPR007300 CidB/LrgB family MADE_1005725 8c7bf0fc716bc2ba7e55b731135f3c0f 247 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 172 242 1.1E-23 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MADE_1005725 8c7bf0fc716bc2ba7e55b731135f3c0f 247 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 121 8.4E-32 T 13-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G MADE_1005725 8c7bf0fc716bc2ba7e55b731135f3c0f 247 SUPERFAMILY SSF117143 77 205 9.02E-21 T 13-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like MADE_1012910 29f57d47d9a7cb0ff852fe4a00e7e9e0 388 SUPERFAMILY SSF53383 6 378 2.89E-109 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1012910 29f57d47d9a7cb0ff852fe4a00e7e9e0 388 Gene3D G3DSA:3.90.1150.10 7 376 1.9E-158 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1012910 29f57d47d9a7cb0ff852fe4a00e7e9e0 388 Pfam PF00266 Aminotransferase class-V 7 371 7.6E-84 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_1012910 29f57d47d9a7cb0ff852fe4a00e7e9e0 388 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 3 387 48.276 T 13-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 MADE_1012910 29f57d47d9a7cb0ff852fe4a00e7e9e0 388 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 199 218 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MADE_1012910 29f57d47d9a7cb0ff852fe4a00e7e9e0 388 Gene3D G3DSA:3.40.640.10 18 264 1.9E-158 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1012910 29f57d47d9a7cb0ff852fe4a00e7e9e0 388 PIRSF PIRSF005572 4 386 1.4E-128 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MADE_1019225 549bcf3b51c2064ebd2cfee2d0c97290 354 Gene3D G3DSA:3.30.70.270 173 353 7.1E-48 T 13-10-2018 MADE_1019225 549bcf3b51c2064ebd2cfee2d0c97290 354 SUPERFAMILY SSF55073 192 351 3.77E-40 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1019225 549bcf3b51c2064ebd2cfee2d0c97290 354 Pfam PF00990 Diguanylate cyclase, GGDEF domain 188 347 1.3E-40 T 13-10-2018 IPR000160 GGDEF domain MADE_1019225 549bcf3b51c2064ebd2cfee2d0c97290 354 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 186 351 1.3E-40 T 13-10-2018 IPR000160 GGDEF domain MADE_1019225 549bcf3b51c2064ebd2cfee2d0c97290 354 SMART SM00267 176 352 8.2E-52 T 13-10-2018 IPR000160 GGDEF domain MADE_1005250 99636c0593524434a3f4a5e4c895b5a0 450 Pfam PF02601 Exonuclease VII, large subunit 129 442 7.0E-97 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 MADE_1005250 99636c0593524434a3f4a5e4c895b5a0 450 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 10 445 28.762 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MADE_1005250 99636c0593524434a3f4a5e4c895b5a0 450 Pfam PF13742 OB-fold nucleic acid binding domain 13 106 5.5E-27 T 13-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 MADE_1005250 99636c0593524434a3f4a5e4c895b5a0 450 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 14 362 5.8E-131 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 MADE_1001515 1943985992662d4776f547492f5e1da2 429 SUPERFAMILY SSF56349 76 383 2.77E-34 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1001515 1943985992662d4776f547492f5e1da2 429 Gene3D G3DSA:1.10.150.130 71 186 3.3E-7 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1001515 1943985992662d4776f547492f5e1da2 429 Gene3D G3DSA:1.10.443.10 187 388 2.0E-23 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1001515 1943985992662d4776f547492f5e1da2 429 Pfam PF13102 Phage integrase SAM-like domain 76 172 1.1E-5 T 13-10-2018 IPR025269 Phage integrase SAM-like domain MADE_1001515 1943985992662d4776f547492f5e1da2 429 Pfam PF00589 Phage integrase family 193 376 1.3E-7 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 Pfam PF09127 Leukotriene A4 hydrolase, C-terminal 531 636 1.3E-24 T 13-10-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 Gene3D G3DSA:1.10.390.10 348 502 1.4E-51 T 13-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 Gene3D G3DSA:2.60.40.1730 68 250 3.6E-64 T 13-10-2018 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 SUPERFAMILY SSF48371 503 636 8.63E-39 T 13-10-2018 IPR016024 Armadillo-type fold MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 Gene3D G3DSA:1.10.1740.60 251 347 4.7E-42 T 13-10-2018 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 SUPERFAMILY SSF63737 57 251 3.14E-44 T 13-10-2018 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 SUPERFAMILY SSF55486 258 495 1.47E-67 T 13-10-2018 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 Pfam PF01433 Peptidase family M1 domain 260 472 1.8E-52 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 Gene3D G3DSA:1.25.40.320 503 641 5.1E-48 T 13-10-2018 IPR038502 Peptidase M1 LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 SMART SM01263 503 642 4.0E-49 T 13-10-2018 IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal GO:0008237|GO:0008270 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 234 249 2.5E-17 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 335 350 2.5E-17 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 308 318 2.5E-17 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 354 366 2.5E-17 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1004445 a064af3b09bcc26d50bd130fb81a60b2 643 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 189 204 2.5E-17 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 SMART SM00962 333 534 1.7E-124 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 Pfam PF00448 SRP54-type protein, GTPase domain 333 533 3.7E-78 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 SMART SM00382 332 533 2.3E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 256 534 62.618 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 507 520 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 Gene3D G3DSA:1.20.120.140 230 532 2.6E-116 T 13-10-2018 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 Pfam PF02881 SRP54-type protein, helical bundle domain 244 308 2.1E-11 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 Gene3D G3DSA:3.40.50.300 326 522 2.6E-116 T 13-10-2018 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 SMART SM00963 233 313 2.2E-22 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 257 533 1.6E-114 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 SUPERFAMILY SSF52540 331 534 9.53E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018385 a0b674b3d9f0b0e656272271c6a32ee3 541 SUPERFAMILY SSF47364 228 306 4.19E-21 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 MADE_1007725 a6adc32719481d8c79f60266fafb7e3b 687 Pfam PF01841 Transglutaminase-like superfamily 383 497 4.3E-21 T 13-10-2018 IPR002931 Transglutaminase-like MADE_1007725 a6adc32719481d8c79f60266fafb7e3b 687 SMART SM00460 430 499 6.3E-16 T 13-10-2018 IPR002931 Transglutaminase-like MADE_1007725 a6adc32719481d8c79f60266fafb7e3b 687 Pfam PF11992 Domain of unknown function (DUF3488) 28 353 2.0E-69 T 13-10-2018 IPR021878 Protein of unknown function DUF3488 MADE_1007725 a6adc32719481d8c79f60266fafb7e3b 687 Gene3D G3DSA:3.10.620.30 354 511 1.9E-20 T 13-10-2018 MADE_1007725 a6adc32719481d8c79f60266fafb7e3b 687 SUPERFAMILY SSF54001 300 612 3.5E-46 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MADE_1015415 2e25b7b10b749f3d46863faf44a388c0 240 Pfam PF03591 AzlC protein 19 157 7.4E-39 T 13-10-2018 IPR011606 Branched-chain amino acid transport, permease MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 Gene3D G3DSA:2.40.30.170 171 184 2.3E-8 T 13-10-2018 MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 Gene3D G3DSA:2.40.30.170 256 333 2.7E-16 T 13-10-2018 MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 Pfam PF13437 HlyD family secretion protein 227 295 2.5E-5 T 13-10-2018 MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 Pfam PF13533 Biotin-lipoyl like 185 222 1.9E-6 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 Gene3D G3DSA:2.40.420.20 334 389 2.7E-16 T 13-10-2018 MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 SUPERFAMILY SSF111369 185 331 2.35E-8 T 13-10-2018 MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 Gene3D G3DSA:2.40.50.100 223 255 2.7E-16 T 13-10-2018 MADE_1001495 a6e3135b1333ea448c9dcbe9470255e2 412 Gene3D G3DSA:2.40.50.100 185 218 2.3E-8 T 13-10-2018 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 6.4E-17 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 6.4E-17 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 6.4E-17 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 Gene3D G3DSA:3.40.710.10 22 282 3.0E-92 T 13-10-2018 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 Gene3D G3DSA:2.60.410.10 284 374 1.1E-25 T 13-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 SUPERFAMILY SSF69189 284 376 2.16E-23 T 13-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 284 374 2.7E-21 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 SMART SM00936 284 374 1.4E-30 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 34 264 4.4E-87 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 MADE_000001021800 9f0673f2b21c8da2466f66fe82f67043 394 SUPERFAMILY SSF56601 14 284 2.49E-83 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_000001022420 f441ac379496f3b331d1b4aa1bead1f5 218 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 212 1.8E-36 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MADE_000001022420 f441ac379496f3b331d1b4aa1bead1f5 218 Gene3D G3DSA:3.90.226.10 2 218 2.6E-58 T 13-10-2018 MADE_000001022420 f441ac379496f3b331d1b4aa1bead1f5 218 SUPERFAMILY SSF52096 7 212 7.08E-42 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1010115 f0619d9ad77a6e1e02001b032cf1ddad 238 Pfam PF04402 Protein of unknown function (DUF541) 39 234 2.0E-38 T 13-10-2018 IPR007497 Protein of unknown function DUF541 MADE_1010115 f0619d9ad77a6e1e02001b032cf1ddad 238 Gene3D G3DSA:3.30.70.2970 51 157 7.2E-43 T 13-10-2018 MADE_1010115 f0619d9ad77a6e1e02001b032cf1ddad 238 Gene3D G3DSA:3.30.110.170 41 234 7.2E-43 T 13-10-2018 MADE_1001080 a068de9b5f234c0455bf704ecb49746d 139 SUPERFAMILY SSF54637 8 133 6.52E-35 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1001080 a068de9b5f234c0455bf704ecb49746d 139 Pfam PF13279 Thioesterase-like superfamily 13 128 5.2E-15 T 13-10-2018 MADE_1001080 a068de9b5f234c0455bf704ecb49746d 139 Gene3D G3DSA:3.10.129.10 8 136 7.7E-35 T 13-10-2018 MADE_1008805 dc39a8ccf81ca197e68c12ed6bff3dd9 181 ProSitePatterns PS00893 Nudix box signature. 79 100 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MADE_1008805 dc39a8ccf81ca197e68c12ed6bff3dd9 181 SUPERFAMILY SSF55811 50 111 2.71E-17 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_1008805 dc39a8ccf81ca197e68c12ed6bff3dd9 181 Gene3D G3DSA:3.90.79.10 30 150 1.2E-16 T 13-10-2018 MADE_1008805 dc39a8ccf81ca197e68c12ed6bff3dd9 181 Pfam PF00293 NUDIX domain 52 110 8.1E-10 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 4 649 0.0 T 13-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 385 403 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 168 180 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 350 371 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 126 150 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 280 301 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 413 432 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 200 218 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 229 248 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 49 74 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 99 122 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 341 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 463 484 6.0E-96 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 282 336 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 Gene3D G3DSA:1.20.210.10 19 565 1.1E-184 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 58 506 6.8E-133 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019585 7b2a1fc576a86dda7654629af619e7ef 662 SUPERFAMILY SSF81442 45 560 9.16E-175 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1015955 9472c4b6fa3aa802984fc34595de09f8 233 SUPERFAMILY SSF101327 12 131 1.96E-6 T 13-10-2018 IPR036255 YgfB-like superfamily MADE_1015955 9472c4b6fa3aa802984fc34595de09f8 233 Pfam PF03695 Uncharacterised protein family (UPF0149) 28 187 1.8E-9 T 13-10-2018 IPR011978 Uncharacterised protein family UPF0149 MADE_1012105 c263807dee2e8e9d8ec500e10f7a7118 279 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 262 2.1E-45 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MADE_1012105 c263807dee2e8e9d8ec500e10f7a7118 279 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 13-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 MADE_1012105 c263807dee2e8e9d8ec500e10f7a7118 279 SUPERFAMILY SSF52096 1 268 3.69E-74 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1012105 c263807dee2e8e9d8ec500e10f7a7118 279 Gene3D G3DSA:1.10.12.10 213 270 3.1E-20 T 13-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MADE_1012105 c263807dee2e8e9d8ec500e10f7a7118 279 Gene3D G3DSA:3.90.226.10 1 212 4.2E-64 T 13-10-2018 MADE_1012565 865838b36b9aff917b9da7d5e00b22ca 83 SUPERFAMILY SSF109910 2 79 3.4E-26 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily MADE_1012565 865838b36b9aff917b9da7d5e00b22ca 83 Pfam PF03937 Flavinator of succinate dehydrogenase 8 77 3.9E-26 T 13-10-2018 IPR005631 Flavinator of succinate dehydrogenase MADE_1012565 865838b36b9aff917b9da7d5e00b22ca 83 Gene3D G3DSA:1.10.150.250 1 83 2.6E-33 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 PIRSF PIRSF005902 1 256 4.0E-83 T 13-10-2018 IPR001130 TatD family GO:0016788 MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 123 133 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 5.8E-89 T 13-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 SUPERFAMILY SSF51556 2 253 3.19E-86 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 Gene3D G3DSA:3.20.20.140 1 261 3.2E-94 T 13-10-2018 MADE_1008735 8039485e93c2dd65232f1c8d13ab8b0c 263 Pfam PF01026 TatD related DNase 3 252 1.1E-76 T 13-10-2018 IPR001130 TatD family GO:0016788 MADE_000001023630 f87818cd3d563ac76719081e85e53db0 893 SUPERFAMILY SSF49785 731 890 3.57E-39 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_000001023630 f87818cd3d563ac76719081e85e53db0 893 SUPERFAMILY SSF49785 365 545 7.4E-30 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_000001023630 f87818cd3d563ac76719081e85e53db0 893 SUPERFAMILY SSF49899 38 329 4.5E-80 T 13-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily MADE_000001023630 f87818cd3d563ac76719081e85e53db0 893 SUPERFAMILY SSF49785 551 727 5.53E-43 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_000001023630 f87818cd3d563ac76719081e85e53db0 893 Gene3D G3DSA:2.60.120.200 40 334 6.9E-90 T 13-10-2018 MADE_000001023630 f87818cd3d563ac76719081e85e53db0 893 Pfam PF00722 Glycosyl hydrolases family 16 82 275 1.1E-26 T 13-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 Gene3D G3DSA:3.40.190.10 168 266 1.1E-51 T 13-10-2018 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 Gene3D G3DSA:3.40.190.10 87 291 1.1E-51 T 13-10-2018 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.7E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 SUPERFAMILY SSF53850 87 293 1.39E-35 T 13-10-2018 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.1E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.1E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.1E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1014955 379c10e39c8a9a336a8134d890321880 356 SUPERFAMILY SSF46785 2 82 8.55E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1014955 379c10e39c8a9a336a8134d890321880 356 Pfam PF03466 LysR substrate binding domain 92 291 1.8E-21 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1014955 379c10e39c8a9a336a8134d890321880 356 Gene3D G3DSA:1.10.10.10 1 85 3.8E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016135 2abc0481e4b89de524d18e5faffff77b 118 SUPERFAMILY SSF55298 3 114 3.61E-30 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MADE_1016135 2abc0481e4b89de524d18e5faffff77b 118 Pfam PF01042 Endoribonuclease L-PSP 5 114 2.5E-22 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MADE_1016135 2abc0481e4b89de524d18e5faffff77b 118 Gene3D G3DSA:3.30.1330.40 1 117 8.9E-40 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 335 65.008 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 310 6.8E-127 T 13-10-2018 IPR017861 Kae1/TsaD family MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 13-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 Gene3D G3DSA:3.30.420.40 3 319 4.2E-132 T 13-10-2018 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.5E-51 T 13-10-2018 IPR017861 Kae1/TsaD family MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.5E-51 T 13-10-2018 IPR017861 Kae1/TsaD family MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 1.5E-51 T 13-10-2018 IPR017861 Kae1/TsaD family MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 1.5E-51 T 13-10-2018 IPR017861 Kae1/TsaD family MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.5E-51 T 13-10-2018 IPR017861 Kae1/TsaD family MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 1.5E-51 T 13-10-2018 IPR017861 Kae1/TsaD family MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 SUPERFAMILY SSF53067 3 123 3.17E-32 T 13-10-2018 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 Gene3D G3DSA:3.30.420.40 129 297 4.2E-132 T 13-10-2018 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 1.1E-136 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 SUPERFAMILY SSF53067 101 313 6.24E-43 T 13-10-2018 MADE_1003785 b8cc06f3c51efc57e9bbe8c6d7895e01 341 Pfam PF00814 Glycoprotease family 24 311 2.2E-104 T 13-10-2018 IPR000905 Gcp-like domain MADE_1006580 c4811b1ec51fb679a0e8e15c677f328d 1015 Gene3D G3DSA:2.40.170.20 481 983 6.8E-52 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1006580 c4811b1ec51fb679a0e8e15c677f328d 1015 SUPERFAMILY SSF56935 179 1014 7.94E-94 T 13-10-2018 MADE_1006580 c4811b1ec51fb679a0e8e15c677f328d 1015 SMART SM00965 103 154 2.3E-4 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MADE_1006580 c4811b1ec51fb679a0e8e15c677f328d 1015 Pfam PF00593 TonB dependent receptor 500 1013 2.2E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1006580 c4811b1ec51fb679a0e8e15c677f328d 1015 Gene3D G3DSA:2.170.130.10 175 319 1.7E-28 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1006580 c4811b1ec51fb679a0e8e15c677f328d 1015 Pfam PF07715 TonB-dependent Receptor Plug Domain 194 315 7.7E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1006580 c4811b1ec51fb679a0e8e15c677f328d 1015 Gene3D G3DSA:3.55.50.30 79 151 4.5E-16 T 13-10-2018 MADE_1015330 22e9ff54735a897b262883193b0064ab 143 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 10 138 2.8E-52 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MADE_1015330 22e9ff54735a897b262883193b0064ab 143 SUPERFAMILY SSF53098 8 138 7.74E-42 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1015330 22e9ff54735a897b262883193b0064ab 143 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 7 142 24.627 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MADE_1015330 22e9ff54735a897b262883193b0064ab 143 SMART SM00732 7 107 5.5E-41 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 MADE_1015330 22e9ff54735a897b262883193b0064ab 143 Gene3D G3DSA:3.30.420.140 5 142 6.8E-44 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 MADE_1015330 22e9ff54735a897b262883193b0064ab 143 Pfam PF03652 Holliday junction resolvase 8 137 1.4E-41 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Gene3D G3DSA:3.30.70.870 288 369 2.4E-34 T 13-10-2018 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 TIGRFAM TIGR01393 lepA: elongation factor 4 5 596 1.8E-301 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Gene3D G3DSA:2.40.30.10 188 287 2.4E-35 T 13-10-2018 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Pfam PF06421 GTP-binding protein LepA C-terminus 489 595 4.2E-49 T 13-10-2018 IPR013842 GTP-binding protein LepA, C-terminal MADE_1012525 1233674bef2f394046c4749a3e63127d 598 SUPERFAMILY SSF54980 294 372 3.6E-18 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1012525 1233674bef2f394046c4749a3e63127d 598 SUPERFAMILY SSF52540 1 207 3.64E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Gene3D G3DSA:3.30.70.2570 481 555 4.8E-33 T 13-10-2018 IPR038363 LepA, C-terminal domain superfamily MADE_1012525 1233674bef2f394046c4749a3e63127d 598 SUPERFAMILY SSF50447 167 290 2.5E-28 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1012525 1233674bef2f394046c4749a3e63127d 598 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_1012525 1233674bef2f394046c4749a3e63127d 598 PRINTS PR00315 GTP-binding elongation factor signature 8 21 4.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 PRINTS PR00315 GTP-binding elongation factor signature 92 103 4.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 PRINTS PR00315 GTP-binding elongation factor signature 128 137 4.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 PRINTS PR00315 GTP-binding elongation factor signature 51 59 4.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 PRINTS PR00315 GTP-binding elongation factor signature 76 86 4.0E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Pfam PF00009 Elongation factor Tu GTP binding domain 5 183 1.5E-53 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Pfam PF03144 Elongation factor Tu domain 2 207 277 1.2E-9 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 SMART SM00838 400 488 0.0058 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like MADE_1012525 1233674bef2f394046c4749a3e63127d 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 178 8.3E-19 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Hamap MF_00071 Elongation factor 4 [lepA]. 1 598 306.821 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Gene3D G3DSA:3.40.50.300 1 187 3.9E-72 T 13-10-2018 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Gene3D G3DSA:3.30.70.3380 370 480 1.2E-41 T 13-10-2018 MADE_1012525 1233674bef2f394046c4749a3e63127d 598 SUPERFAMILY SSF54980 401 495 3.41E-25 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1012525 1233674bef2f394046c4749a3e63127d 598 Pfam PF00679 Elongation factor G C-terminus 401 485 2.9E-20 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like MADE_1003465 9382b8e4e1b657c8836cc2fcec3df128 356 Pfam PF00072 Response regulator receiver domain 5 114 2.7E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1003465 9382b8e4e1b657c8836cc2fcec3df128 356 Gene3D G3DSA:3.40.1550.10 155 349 9.5E-38 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1003465 9382b8e4e1b657c8836cc2fcec3df128 356 SUPERFAMILY SSF52172 4 118 2.99E-30 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1003465 9382b8e4e1b657c8836cc2fcec3df128 356 Gene3D G3DSA:3.40.50.2300 3 154 7.0E-30 T 13-10-2018 MADE_1003465 9382b8e4e1b657c8836cc2fcec3df128 356 SUPERFAMILY SSF103039 152 343 1.37E-40 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1003465 9382b8e4e1b657c8836cc2fcec3df128 356 SMART SM00448 3 115 2.7E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1010500 2c43ebe260e4488bfcb906913d0a1f87 208 Pfam PF01810 LysE type translocator 16 207 8.1E-30 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MADE_1010500 2c43ebe260e4488bfcb906913d0a1f87 208 PIRSF PIRSF006324 1 208 2.2E-45 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MADE_1006265 26a3bc7462d4e1813177078da22bf633 132 Gene3D G3DSA:3.30.420.270 60 128 1.8E-11 T 13-10-2018 MADE_1006265 26a3bc7462d4e1813177078da22bf633 132 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 130 1.0E-30 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MADE_1014010 4616bdef8df151b103f6b2a605059bba 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.011 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MADE_1014010 4616bdef8df151b103f6b2a605059bba 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 2.4E-54 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MADE_1014010 4616bdef8df151b103f6b2a605059bba 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.8E-59 T 13-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 MADE_1014010 4616bdef8df151b103f6b2a605059bba 122 Gene3D G3DSA:2.40.150.20 1 122 1.6E-53 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1014010 4616bdef8df151b103f6b2a605059bba 122 SUPERFAMILY SSF50193 1 122 5.36E-51 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1014010 4616bdef8df151b103f6b2a605059bba 122 SMART SM01374 1 122 8.4E-85 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 MADE_1019120 25bbd3014b8ad16818e79bd68efc10f7 168 Gene3D G3DSA:3.30.70.270 1 167 3.6E-42 T 13-10-2018 MADE_1019120 25bbd3014b8ad16818e79bd68efc10f7 168 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1 165 1.2E-36 T 13-10-2018 IPR000160 GGDEF domain MADE_1019120 25bbd3014b8ad16818e79bd68efc10f7 168 SMART SM00267 1 165 5.4E-26 T 13-10-2018 IPR000160 GGDEF domain MADE_1019120 25bbd3014b8ad16818e79bd68efc10f7 168 Pfam PF00990 Diguanylate cyclase, GGDEF domain 5 160 2.1E-32 T 13-10-2018 IPR000160 GGDEF domain MADE_1019120 25bbd3014b8ad16818e79bd68efc10f7 168 SUPERFAMILY SSF55073 10 165 3.3E-34 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1006625 aa4bf130b17d5d0a67eaea1b7a6174ff 471 SUPERFAMILY SSF53187 39 465 1.28E-54 T 13-10-2018 MADE_1006625 aa4bf130b17d5d0a67eaea1b7a6174ff 471 Pfam PF04389 Peptidase family M28 267 452 4.0E-27 T 13-10-2018 IPR007484 Peptidase M28 MADE_1006625 aa4bf130b17d5d0a67eaea1b7a6174ff 471 Gene3D G3DSA:3.50.30.30 106 256 2.0E-137 T 13-10-2018 MADE_1006625 aa4bf130b17d5d0a67eaea1b7a6174ff 471 Gene3D G3DSA:3.40.630.10 53 456 2.0E-137 T 13-10-2018 MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 165 269 2.4E-28 T 13-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 Gene3D G3DSA:3.40.50.720 1 165 2.8E-50 T 13-10-2018 MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 PIRSF PIRSF000193 3 272 6.0E-73 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 Gene3D G3DSA:1.10.3730.10 166 273 1.8E-31 T 13-10-2018 MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 SUPERFAMILY SSF48179 164 272 6.29E-28 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 SUPERFAMILY SSF51735 4 161 1.02E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 100 9.6E-22 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 269 1.8E-73 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MADE_1015355 ce0f1e9267f1d11d0e775c66e1645d2c 273 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 269 24.69 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Gene3D G3DSA:3.40.50.720 233 366 2.6E-37 T 13-10-2018 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Gene3D G3DSA:3.40.50.720 2 139 3.4E-48 T 13-10-2018 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Pfam PF02080 TrkA-C domain 391 451 1.3E-11 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Pfam PF02080 TrkA-C domain 156 225 1.2E-9 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 SUPERFAMILY SSF116726 147 226 8.24E-10 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 4.1E-31 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 4.1E-31 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 4.1E-31 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 4.1E-31 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 4.1E-31 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Gene3D G3DSA:3.30.70.1450 140 232 1.3E-20 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 SUPERFAMILY SSF51735 1 151 2.99E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 SUPERFAMILY SSF51735 233 376 8.05E-33 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Pfam PF02254 TrkA-N domain 3 125 9.5E-29 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Pfam PF02254 TrkA-N domain 235 350 9.9E-24 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 SUPERFAMILY SSF116726 362 437 1.7E-9 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1000090 f153a409ae3024e4142e24ba9c9670d2 459 Gene3D G3DSA:3.30.70.1450 367 458 1.5E-30 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 Pfam PF03466 LysR substrate binding domain 99 292 8.5E-41 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 Gene3D G3DSA:1.10.10.10 4 91 4.0E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 3.2E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.5E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.5E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.5E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 Gene3D G3DSA:3.40.190.10 100 298 1.1E-52 T 13-10-2018 MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 SUPERFAMILY SSF46785 7 117 5.97E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 SUPERFAMILY SSF53850 101 289 6.32E-37 T 13-10-2018 MADE_1006060 fa539d9d2e56b81afeb00fae0e309872 322 Gene3D G3DSA:3.40.190.10 168 269 1.1E-52 T 13-10-2018 MADE_1012630 23e0675bf940f31e4858f1e6779744bd 187 Pfam PF14341 PilX N-terminal 6 53 3.7E-7 T 13-10-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 Pfam PF01037 Lrp/AsnC ligand binding domain 75 148 2.8E-19 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 SUPERFAMILY SSF46785 7 99 3.81E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 27 53 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.5E-12 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.5E-12 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.5E-12 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 Gene3D G3DSA:3.30.70.920 62 145 1.9E-23 T 13-10-2018 MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 SUPERFAMILY SSF54909 71 151 2.32E-20 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 55 6.8E-18 T 13-10-2018 MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 SMART SM00344 9 118 1.7E-44 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 MADE_1018130 7d13e8bd846ff04f173308b4347ad8ea 160 Gene3D G3DSA:1.10.10.10 9 61 4.7E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1011560 41b809e47cb1e1773a05585081964ad0 150 Gene3D G3DSA:3.40.50.2300 1 150 3.2E-36 T 13-10-2018 MADE_1011560 41b809e47cb1e1773a05585081964ad0 150 Pfam PF00072 Response regulator receiver domain 11 133 2.5E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011560 41b809e47cb1e1773a05585081964ad0 150 SMART SM00448 9 134 6.1E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011560 41b809e47cb1e1773a05585081964ad0 150 SUPERFAMILY SSF52172 6 145 2.28E-33 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 Gene3D G3DSA:3.40.50.300 347 593 6.8E-92 T 13-10-2018 MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 SUPERFAMILY SSF90123 16 327 1.83E-72 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 SMART SM00382 381 561 1.6E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 Gene3D G3DSA:1.20.1560.10 11 336 2.6E-80 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 Pfam PF00664 ABC transporter transmembrane region 31 293 6.4E-54 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 Pfam PF00005 ABC transporter 373 521 1.7E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 SUPERFAMILY SSF52540 352 592 6.21E-90 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001021035 1b5f3158be0b940aca255a231caa5329 594 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1009780 6615c475887054d8e875589d7e270189 263 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 198 210 1.8E-7 T 13-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 MADE_1009780 6615c475887054d8e875589d7e270189 263 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 110 124 1.8E-7 T 13-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 MADE_1009780 6615c475887054d8e875589d7e270189 263 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 47 62 1.8E-7 T 13-10-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 MADE_1009780 6615c475887054d8e875589d7e270189 263 SMART SM00020 11 256 1.8E-4 T 13-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 MADE_1009780 6615c475887054d8e875589d7e270189 263 Pfam PF00089 Trypsin 48 256 3.9E-14 T 13-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 MADE_1009780 6615c475887054d8e875589d7e270189 263 SUPERFAMILY SSF50494 44 262 9.68E-28 T 13-10-2018 IPR009003 Peptidase S1, PA clan MADE_1009780 6615c475887054d8e875589d7e270189 263 Gene3D G3DSA:2.40.10.10 47 263 2.0E-21 T 13-10-2018 MADE_1000975 487b202dc9375f113c3bf9cedfa9ab74 310 TIGRFAM TIGR00688 rarD: protein RarD 17 268 2.8E-76 T 13-10-2018 IPR004626 RarD protein GO:0005887 MADE_1000975 487b202dc9375f113c3bf9cedfa9ab74 310 SUPERFAMILY SSF103481 50 154 1.96E-13 T 13-10-2018 MADE_1000975 487b202dc9375f113c3bf9cedfa9ab74 310 Pfam PF00892 EamA-like transporter family 16 152 4.7E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1000975 487b202dc9375f113c3bf9cedfa9ab74 310 SUPERFAMILY SSF103481 192 292 1.01E-5 T 13-10-2018 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 334 2.6E-139 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 SUPERFAMILY SSF51735 1 336 6.29E-98 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 Gene3D G3DSA:3.90.25.10 193 328 2.5E-141 T 13-10-2018 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 Gene3D G3DSA:3.40.50.720 3 273 2.5E-141 T 13-10-2018 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 5.3E-7 T 13-10-2018 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 5.3E-7 T 13-10-2018 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 5.3E-7 T 13-10-2018 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 5.3E-7 T 13-10-2018 MADE_1001165 3cf2b4b2fd8efbd72c67411aa2fae640 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 3.0E-57 T 13-10-2018 IPR016040 NAD(P)-binding domain MADE_1008885 34a609a6521badf91c517d2e8869d3aa 328 SUPERFAMILY SSF82689 184 282 3.14E-24 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1008885 34a609a6521badf91c517d2e8869d3aa 328 SUPERFAMILY SSF50182 116 181 5.56E-15 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1008885 34a609a6521badf91c517d2e8869d3aa 328 Gene3D G3DSA:3.30.70.100 184 277 3.0E-22 T 13-10-2018 MADE_1008885 34a609a6521badf91c517d2e8869d3aa 328 SUPERFAMILY SSF82861 28 114 8.11E-12 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MADE_1008885 34a609a6521badf91c517d2e8869d3aa 328 Pfam PF00924 Mechanosensitive ion channel 71 271 7.7E-47 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1008885 34a609a6521badf91c517d2e8869d3aa 328 Gene3D G3DSA:2.30.30.60 131 180 3.2E-12 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1002285 931c99462dfe7b8423df07c6c49c2d38 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 28.863 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002285 931c99462dfe7b8423df07c6c49c2d38 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 7.1E-39 T 13-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 MADE_1002285 931c99462dfe7b8423df07c6c49c2d38 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 13-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002285 931c99462dfe7b8423df07c6c49c2d38 110 SUPERFAMILY SSF54843 1 109 4.58E-43 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1002285 931c99462dfe7b8423df07c6c49c2d38 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 2.6E-48 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002285 931c99462dfe7b8423df07c6c49c2d38 110 Gene3D G3DSA:3.90.470.10 1 110 9.8E-46 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1018100 c37aa10e8fcd80658aa9b750493cc789 341 SUPERFAMILY SSF53850 51 250 9.88E-14 T 13-10-2018 MADE_1018100 c37aa10e8fcd80658aa9b750493cc789 341 Gene3D G3DSA:3.40.190.10 118 214 8.9E-9 T 13-10-2018 MADE_1018100 c37aa10e8fcd80658aa9b750493cc789 341 Gene3D G3DSA:3.40.190.10 61 250 8.9E-9 T 13-10-2018 MADE_1002900 39ffa65fd0b8cba536f7ef3c8e7c4fa1 389 Gene3D G3DSA:2.120.10.30 42 389 3.1E-114 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1002900 39ffa65fd0b8cba536f7ef3c8e7c4fa1 389 SUPERFAMILY SSF50952 45 387 2.48E-47 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MADE_1002900 39ffa65fd0b8cba536f7ef3c8e7c4fa1 389 Pfam PF07995 Glucose / Sorbosone dehydrogenase 57 385 2.6E-126 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase MADE_000001022350 75a6de9a0b84b950c696f3dd0500ab8b 273 Gene3D G3DSA:3.40.50.300 3 265 1.4E-22 T 13-10-2018 MADE_000001022350 75a6de9a0b84b950c696f3dd0500ab8b 273 SUPERFAMILY SSF52540 3 262 2.96E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022350 75a6de9a0b84b950c696f3dd0500ab8b 273 Pfam PF00685 Sulfotransferase domain 4 231 4.6E-14 T 13-10-2018 IPR000863 Sulfotransferase domain GO:0008146 MADE_1007750 24eddcb8fca610a0bc9fc0f244c0e0c5 825 Gene3D G3DSA:3.40.50.2000 484 811 0.0 T 13-10-2018 MADE_1007750 24eddcb8fca610a0bc9fc0f244c0e0c5 825 Pfam PF00343 Carbohydrate phosphorylase 104 818 0.0 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MADE_1007750 24eddcb8fca610a0bc9fc0f244c0e0c5 825 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 662 674 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MADE_1007750 24eddcb8fca610a0bc9fc0f244c0e0c5 825 PIRSF PIRSF000460 2 825 8.4E-227 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MADE_1007750 24eddcb8fca610a0bc9fc0f244c0e0c5 825 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 16 818 0.0 T 13-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 MADE_1007750 24eddcb8fca610a0bc9fc0f244c0e0c5 825 Gene3D G3DSA:3.40.50.2000 25 818 0.0 T 13-10-2018 MADE_1007750 24eddcb8fca610a0bc9fc0f244c0e0c5 825 SUPERFAMILY SSF53756 11 823 0.0 T 13-10-2018 MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 37 142 1.5E-11 T 13-10-2018 IPR000014 PAS domain MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 Gene3D G3DSA:3.30.70.270 142 323 5.7E-57 T 13-10-2018 MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 143 307 9.6E-42 T 13-10-2018 IPR000160 GGDEF domain MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 SUPERFAMILY SSF55785 37 145 3.32E-15 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 Pfam PF00990 Diguanylate cyclase, GGDEF domain 147 305 1.6E-46 T 13-10-2018 IPR000160 GGDEF domain MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 SMART SM00091 21 88 1.6E-5 T 13-10-2018 IPR000014 PAS domain MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 Pfam PF00563 EAL domain 325 560 3.7E-67 T 13-10-2018 IPR001633 EAL domain MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 SUPERFAMILY SSF141868 326 572 4.32E-78 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 Gene3D G3DSA:3.30.450.20 33 138 2.4E-13 T 13-10-2018 MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 Gene3D G3DSA:3.20.20.450 324 573 1.8E-87 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 SUPERFAMILY SSF55073 152 310 8.44E-48 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 SMART SM00267 136 309 1.4E-57 T 13-10-2018 IPR000160 GGDEF domain MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 Pfam PF08447 PAS fold 43 121 2.5E-8 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 MADE_1007850 4a3c5202ead3fe86ff39e64e8382e23f 573 SMART SM00052 319 565 6.0E-92 T 13-10-2018 IPR001633 EAL domain MADE_1004200 06d1d8dc38c0108eb82f9c4b41a9ad86 192 Gene3D G3DSA:2.60.450.10 65 192 6.1E-41 T 13-10-2018 MADE_1004200 06d1d8dc38c0108eb82f9c4b41a9ad86 192 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 17 188 4.6E-40 T 13-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related MADE_1004200 06d1d8dc38c0108eb82f9c4b41a9ad86 192 PIRSF PIRSF028513 6 192 7.4E-61 T 13-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MADE_1004200 06d1d8dc38c0108eb82f9c4b41a9ad86 192 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 15 188 2.0E-46 T 13-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MADE_1004200 06d1d8dc38c0108eb82f9c4b41a9ad86 192 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 7 191 24.662 T 13-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 MADE_1008035 bdf300df9c9c1362c3ecafe145565654 423 Gene3D G3DSA:3.90.1300.10 11 422 5.0E-91 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MADE_1008035 bdf300df9c9c1362c3ecafe145565654 423 Pfam PF01425 Amidase 39 229 3.8E-51 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MADE_1008035 bdf300df9c9c1362c3ecafe145565654 423 Pfam PF01425 Amidase 315 414 7.1E-11 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MADE_1008035 bdf300df9c9c1362c3ecafe145565654 423 ProSitePatterns PS00571 Amidases signature. 139 170 - T 13-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 MADE_1008035 bdf300df9c9c1362c3ecafe145565654 423 SUPERFAMILY SSF75304 48 420 2.75E-85 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 176 7.8E-47 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 6 98 25.501 T 13-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 Gene3D G3DSA:2.40.240.10 5 98 4.7E-34 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 SUPERFAMILY SSF50715 6 200 6.8E-56 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 Pfam PF01386 Ribosomal L25p family 8 95 6.8E-27 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 6 191 31.097 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 104 192 8.6E-30 T 13-10-2018 IPR020057 Ribosomal protein L25, beta domain MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 Gene3D G3DSA:2.170.120.20 101 201 4.5E-27 T 13-10-2018 IPR037121 Ribosomal protein L25, C-terminal MADE_1007570 b26db40d161c4e59117d66b40ce05969 210 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 10 98 1.0E-33 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 MADE_000001023230 125704e29f09ea7413fab0847d72e122 572 Pfam PF00664 ABC transporter transmembrane region 29 294 3.4E-12 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_000001023230 125704e29f09ea7413fab0847d72e122 572 Gene3D G3DSA:1.20.1560.10 11 325 2.7E-26 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001023230 125704e29f09ea7413fab0847d72e122 572 SUPERFAMILY SSF90123 11 324 4.71E-35 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001023230 125704e29f09ea7413fab0847d72e122 572 Gene3D G3DSA:3.40.50.300 332 551 1.3E-13 T 13-10-2018 MADE_000001023230 125704e29f09ea7413fab0847d72e122 572 SUPERFAMILY SSF52540 376 521 6.5E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009415 6dd1a25b776bc6dcf136f0ee5aea7ec9 64 Pfam PF03966 Trm112p-like protein 4 43 1.1E-8 T 13-10-2018 IPR005651 Trm112-like MADE_1009415 6dd1a25b776bc6dcf136f0ee5aea7ec9 64 Gene3D G3DSA:2.20.25.10 10 64 2.0E-19 T 13-10-2018 MADE_1009415 6dd1a25b776bc6dcf136f0ee5aea7ec9 64 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 3 56 24.073 T 13-10-2018 IPR038053 Uncharacterised protein family UPF0434 MADE_1009415 6dd1a25b776bc6dcf136f0ee5aea7ec9 64 SUPERFAMILY SSF158997 1 56 3.66E-17 T 13-10-2018 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 SUPERFAMILY SSF51621 463 787 8.38E-98 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 SUPERFAMILY SSF52009 349 466 6.41E-34 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 SUPERFAMILY SSF56059 2 384 2.83E-106 T 13-10-2018 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 Gene3D G3DSA:3.20.20.60 478 789 4.1E-103 T 13-10-2018 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 346 4.9E-117 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 Gene3D G3DSA:3.50.30.10 371 477 3.4E-40 T 13-10-2018 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 5 787 0.0 T 13-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 PIRSF PIRSF000854 1 790 0.0 T 13-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 414 425 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 482 783 1.2E-60 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 Pfam PF00391 PEP-utilising enzyme, mobile domain 384 455 5.5E-27 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 Gene3D G3DSA:3.30.470.20 194 357 4.3E-58 T 13-10-2018 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 694 712 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 MADE_1008600 109f897703b5f7e686cc156e2417e49e 790 Gene3D G3DSA:3.30.1490.20 1 193 2.1E-71 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 SMART SM00382 28 230 1.4E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 SMART SM00382 344 515 7.1E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 Gene3D G3DSA:3.40.50.300 2 279 6.0E-68 T 13-10-2018 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 Pfam PF00005 ABC transporter 336 469 4.6E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 SUPERFAMILY SSF52540 312 515 1.78E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 SUPERFAMILY SSF52540 3 243 7.64E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 Pfam PF00005 ABC transporter 19 185 7.3E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 Pfam PF16326 ABC transporter C-terminal domain 570 638 2.0E-18 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 Pfam PF12848 ABC transporter 224 294 7.2E-13 T 13-10-2018 IPR032781 ABC-transporter extension domain MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 Gene3D G3DSA:3.40.50.300 281 552 4.9E-63 T 13-10-2018 MADE_1010185 a266a2e37482970e3beac4f83d98c08f 646 Gene3D G3DSA:1.10.287.380 560 643 2.2E-24 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 MADE_1019760 bebb529edb60d123598c49f679ba57df 253 Pfam PF06452 Carbohydrate family 9 binding domain-like 40 252 5.0E-50 T 13-10-2018 IPR010502 Carbohydrate-binding domain, family 9 GO:0004553|GO:0016052|GO:0030246 MetaCyc: PWY-6717|MetaCyc: PWY-6784 MADE_1019760 bebb529edb60d123598c49f679ba57df 253 Gene3D G3DSA:2.60.40.1190 33 252 1.1E-35 T 13-10-2018 MADE_1019760 bebb529edb60d123598c49f679ba57df 253 ProDom PD004647 DEGRADATION HYDROLASE GLYCOSIDASE XYLAN A XYLANASE PRECURSOR SIGNAL REPEAT 14- 38 253 5.0E-5 T 13-10-2018 MADE_1019760 bebb529edb60d123598c49f679ba57df 253 SUPERFAMILY SSF49344 31 252 4.32E-33 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 SMART SM00173 1 160 3.1E-7 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 Gene3D G3DSA:3.40.50.300 2 160 4.2E-42 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 PRINTS PR00449 Transforming protein P21 ras signature 27 43 1.9E-22 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 PRINTS PR00449 Transforming protein P21 ras signature 106 119 1.9E-22 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 PRINTS PR00449 Transforming protein P21 ras signature 140 161 1.9E-22 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 PRINTS PR00449 Transforming protein P21 ras signature 4 25 1.9E-22 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 PRINTS PR00449 Transforming protein P21 ras signature 45 67 1.9E-22 T 13-10-2018 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 Pfam PF00071 Ras family 5 159 2.0E-29 T 13-10-2018 IPR001806 Small GTPase GO:0003924|GO:0005525 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 158 3.0E-19 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 SUPERFAMILY SSF52540 4 159 2.2E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1016935 7499ff969ddf4b3f9ef646b405a3090d 161 SMART SM00175 5 159 1.2E-10 T 13-10-2018 MADE_1018045 70e02901f4f6bf0d4699d8692f06a36d 82 SUPERFAMILY SSF47598 4 45 1.63E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1018045 70e02901f4f6bf0d4699d8692f06a36d 82 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 6.1E-10 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 SUPERFAMILY SSF53098 7 400 1.45E-61 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 427 440 1.6E-10 T 13-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 499 511 1.6E-10 T 13-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 551 559 1.6E-10 T 13-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 SMART SM00486 158 565 1.2E-50 T 13-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 ProSitePatterns PS00116 DNA polymerase family B signature. 553 561 - T 13-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Gene3D G3DSA:3.90.1600.10 469 639 2.4E-43 T 13-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Gene3D G3DSA:3.90.1600.10 360 452 2.4E-23 T 13-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Gene3D G3DSA:3.30.70.2250 44 111 5.5E-31 T 13-10-2018 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Pfam PF03104 DNA polymerase family B, exonuclease domain 83 309 5.6E-18 T 13-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Gene3D G3DSA:1.10.132.60 646 790 5.9E-56 T 13-10-2018 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 SUPERFAMILY SSF56672 398 785 1.5E-111 T 13-10-2018 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Gene3D G3DSA:3.30.420.10 161 359 2.4E-61 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Pfam PF00136 DNA polymerase family B 390 745 2.4E-36 T 13-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_1016665 b8b1ad84a820721540e1049988ca305e 790 Gene3D G3DSA:2.40.50.590 9 156 5.5E-31 T 13-10-2018 MADE_1014380 333100b01b50710d3be55c751a6460ea 306 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 17 240 6.7E-48 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MADE_1014380 333100b01b50710d3be55c751a6460ea 306 Gene3D G3DSA:3.100.10.20 1 95 1.4E-40 T 13-10-2018 MADE_1014380 333100b01b50710d3be55c751a6460ea 306 Gene3D G3DSA:1.20.120.920 96 292 2.4E-85 T 13-10-2018 MADE_1014380 333100b01b50710d3be55c751a6460ea 306 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 14 300 17.318 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MADE_1014380 333100b01b50710d3be55c751a6460ea 306 Pfam PF01867 CRISPR associated protein Cas1 130 226 1.3E-9 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 MADE_1014380 333100b01b50710d3be55c751a6460ea 306 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 7 273 1.2E-112 T 13-10-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 MADE_1009085 3c6dbc71d062243371c606cee5c3c8cd 218 Gene3D G3DSA:1.20.120.1760 6 199 5.5E-26 T 13-10-2018 MADE_1009085 3c6dbc71d062243371c606cee5c3c8cd 218 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MADE_1009085 3c6dbc71d062243371c606cee5c3c8cd 218 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 90 4.5E-13 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MADE_1002675 5e3831fe0f77c3baf9154cbf0c4106cf 275 Pfam PF07813 LTXXQ motif family protein 165 262 2.6E-6 T 13-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 MADE_1002675 5e3831fe0f77c3baf9154cbf0c4106cf 275 Pfam PF07813 LTXXQ motif family protein 41 127 5.6E-7 T 13-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 MADE_1002675 5e3831fe0f77c3baf9154cbf0c4106cf 275 Gene3D G3DSA:1.20.120.1490 166 275 4.8E-18 T 13-10-2018 MADE_1002675 5e3831fe0f77c3baf9154cbf0c4106cf 275 Gene3D G3DSA:1.20.120.1490 27 134 1.9E-14 T 13-10-2018 MADE_1005655 75ced022573f19c7902325c11d0a3e9c 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 132 185 8.5E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1005655 75ced022573f19c7902325c11d0a3e9c 198 SMART SM00421 131 188 1.5E-20 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1005655 75ced022573f19c7902325c11d0a3e9c 198 Gene3D G3DSA:1.10.10.10 82 196 5.1E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1005655 75ced022573f19c7902325c11d0a3e9c 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 164 1.5E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1005655 75ced022573f19c7902325c11d0a3e9c 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 134 148 1.5E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1005655 75ced022573f19c7902325c11d0a3e9c 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 176 1.5E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1005655 75ced022573f19c7902325c11d0a3e9c 198 SUPERFAMILY SSF46894 124 190 1.9E-17 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1013345 edea0a3f40b3ccbe28abe2529b0dbe90 668 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 480 632 1.5E-39 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1013345 edea0a3f40b3ccbe28abe2529b0dbe90 668 SMART SM00304 339 391 1.8E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1013345 edea0a3f40b3ccbe28abe2529b0dbe90 668 Gene3D G3DSA:1.10.287.950 338 668 1.0E-64 T 13-10-2018 MADE_1013345 edea0a3f40b3ccbe28abe2529b0dbe90 668 SMART SM00283 406 667 4.9E-57 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1013345 edea0a3f40b3ccbe28abe2529b0dbe90 668 SUPERFAMILY SSF58104 359 668 4.71E-67 T 13-10-2018 MADE_1013345 edea0a3f40b3ccbe28abe2529b0dbe90 668 Pfam PF00672 HAMP domain 339 388 2.9E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 MADE_1000470 e5b9fc9c01375b08d0f99668e2a48fd8 287 SUPERFAMILY SSF56281 9 285 1.31E-49 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1000470 e5b9fc9c01375b08d0f99668e2a48fd8 287 Pfam PF00753 Metallo-beta-lactamase superfamily 15 205 8.3E-19 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1000470 e5b9fc9c01375b08d0f99668e2a48fd8 287 SMART SM00849 14 205 1.4E-27 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1000470 e5b9fc9c01375b08d0f99668e2a48fd8 287 Gene3D G3DSA:3.60.15.10 1 287 3.1E-109 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 4.3E-169 T 13-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 Pfam PF00575 S1 RNA binding domain 36 118 2.8E-14 T 13-10-2018 IPR003029 S1 domain GO:0003676 MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 Pfam PF10150 Ribonuclease E/G family 121 390 7.1E-95 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 Gene3D G3DSA:3.40.1260.20 400 507 8.1E-36 T 13-10-2018 MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 SMART SM00316 37 119 1.2E-9 T 13-10-2018 IPR022967 RNA-binding domain, S1 MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 SUPERFAMILY SSF50249 40 124 1.04E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 Hamap MF_00970 Ribonuclease E [rne]. 1 1069 34.848 T 13-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 MADE_1008655 086c1c75c3e88fe9550ca553a605c454 1134 Gene3D G3DSA:2.40.50.140 32 125 4.3E-31 T 13-10-2018 MADE_1008895 e58836c5709c56bcada6903bd614c66c 100 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 98 3.4E-29 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MADE_1008895 e58836c5709c56bcada6903bd614c66c 100 SUPERFAMILY SSF55248 3 99 2.49E-30 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MADE_1008895 e58836c5709c56bcada6903bd614c66c 100 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 2 100 22.535 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MADE_1008895 e58836c5709c56bcada6903bd614c66c 100 Gene3D G3DSA:3.30.1360.20 1 100 9.4E-33 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 MADE_000001021300 ac7ad72f03930f3c47bd7f2b19f026f6 231 Gene3D G3DSA:1.10.10.10 1 84 8.4E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001021300 ac7ad72f03930f3c47bd7f2b19f026f6 231 Gene3D G3DSA:3.40.190.290 90 230 2.9E-40 T 13-10-2018 MADE_000001021300 ac7ad72f03930f3c47bd7f2b19f026f6 231 Pfam PF03466 LysR substrate binding domain 87 226 9.1E-26 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_000001021300 ac7ad72f03930f3c47bd7f2b19f026f6 231 SUPERFAMILY SSF46785 1 111 3.8E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001021300 ac7ad72f03930f3c47bd7f2b19f026f6 231 SUPERFAMILY SSF53850 89 226 1.05E-26 T 13-10-2018 MADE_000001021300 ac7ad72f03930f3c47bd7f2b19f026f6 231 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.5E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.2E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 SUPERFAMILY SSF51735 3 225 4.23E-52 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.5E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.5E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.5E-10 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 Pfam PF00106 short chain dehydrogenase 3 198 4.2E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_000001021945 c714948f9dceb68030a1f48112c2cba7 234 Gene3D G3DSA:3.40.50.720 2 234 2.9E-60 T 13-10-2018 MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 SUPERFAMILY SSF88659 124 186 3.55E-17 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 Pfam PF08281 Sigma-70, region 4 135 181 4.3E-16 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 Gene3D G3DSA:1.10.10.10 122 191 2.6E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 SUPERFAMILY SSF88946 2 108 1.38E-31 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 184 2.1E-33 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 190 3.8E-97 T 13-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 Gene3D G3DSA:1.10.1740.10 1 121 2.2E-43 T 13-10-2018 MADE_1012545 4446ea77f1947f4b6f3db0545660aed7 192 Pfam PF04542 Sigma-70 region 2 25 92 1.9E-18 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_000001022415 c58910461b4424b4d55014ccc1e228b6 261 SMART SM00967 22 101 2.1E-6 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MADE_000001022415 c58910461b4424b4d55014ccc1e228b6 261 SUPERFAMILY SSF55315 3 98 1.88E-14 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like MADE_000001022415 c58910461b4424b4d55014ccc1e228b6 261 Gene3D G3DSA:3.40.1280.10 108 261 1.3E-31 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_000001022415 c58910461b4424b4d55014ccc1e228b6 261 Gene3D G3DSA:3.30.1330.30 1 99 4.6E-10 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like MADE_000001022415 c58910461b4424b4d55014ccc1e228b6 261 SUPERFAMILY SSF75217 113 261 3.73E-28 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_000001022415 c58910461b4424b4d55014ccc1e228b6 261 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 22 97 5.2E-8 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 MADE_000001022415 c58910461b4424b4d55014ccc1e228b6 261 Pfam PF00588 SpoU rRNA Methylase family 122 257 1.3E-25 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MADE_1020350 14ace6b0c68b956ceea0dfce698c3f5e 65 Pfam PF12728 Helix-turn-helix domain 6 54 2.0E-18 T 13-10-2018 MADE_1020350 14ace6b0c68b956ceea0dfce698c3f5e 65 SUPERFAMILY SSF46955 5 53 1.37E-10 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1020350 14ace6b0c68b956ceea0dfce698c3f5e 65 Gene3D G3DSA:1.10.1660.10 3 56 2.3E-12 T 13-10-2018 MADE_1020350 14ace6b0c68b956ceea0dfce698c3f5e 65 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 53 2.9E-21 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 MADE_1014445 ed904363b6f9faee89b41799e2c9273d 304 Gene3D G3DSA:3.30.420.40 128 275 3.5E-66 T 13-10-2018 MADE_1014445 ed904363b6f9faee89b41799e2c9273d 304 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 8 280 4.3E-19 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 MADE_1014445 ed904363b6f9faee89b41799e2c9273d 304 SUPERFAMILY SSF53067 5 124 4.78E-19 T 13-10-2018 MADE_1014445 ed904363b6f9faee89b41799e2c9273d 304 Gene3D G3DSA:3.30.420.40 6 127 3.5E-66 T 13-10-2018 MADE_1014445 ed904363b6f9faee89b41799e2c9273d 304 SUPERFAMILY SSF53067 127 297 2.96E-35 T 13-10-2018 MADE_1004890 b4d8627139094790d6bcb5300d2f44eb 454 Pfam PF03641 Possible lysine decarboxylase 188 327 2.5E-32 T 13-10-2018 IPR031100 LOG family MADE_1004890 b4d8627139094790d6bcb5300d2f44eb 454 Gene3D G3DSA:3.40.50.450 120 450 9.7E-117 T 13-10-2018 MADE_1004890 b4d8627139094790d6bcb5300d2f44eb 454 Gene3D G3DSA:3.30.1850.10 1 114 1.2E-42 T 13-10-2018 IPR037153 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase YgdH-like superfamily KEGG: 00230+3.2.2.4|KEGG: 00240+3.2.2.10|MetaCyc: PWY-6617|MetaCyc: PWY-7569|MetaCyc: PWY-7570 MADE_1004890 b4d8627139094790d6bcb5300d2f44eb 454 SUPERFAMILY SSF102405 127 327 8.55E-41 T 13-10-2018 MADE_1004890 b4d8627139094790d6bcb5300d2f44eb 454 Pfam PF11892 Domain of unknown function (DUF3412) 332 450 2.3E-55 T 13-10-2018 IPR021826 Domain of unknown function DUF3412 KEGG: 00230+3.2.2.4|KEGG: 00240+3.2.2.10|MetaCyc: PWY-6617|MetaCyc: PWY-7569|MetaCyc: PWY-7570 MADE_1004890 b4d8627139094790d6bcb5300d2f44eb 454 Pfam PF14793 Domain of unknown function (DUF4478) 5 111 8.3E-43 T 13-10-2018 IPR027820 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase YgdH, N-terminal KEGG: 00230+3.2.2.4|KEGG: 00240+3.2.2.10|MetaCyc: PWY-6617|MetaCyc: PWY-7569|MetaCyc: PWY-7570 MADE_1010220 99931b1c61101ee937673bc919d57529 45 Pfam PF10013 Uncharacterized protein conserved in bacteria (DUF2256) 2 40 1.0E-22 T 13-10-2018 IPR017136 Uncharacterised conserved protein UCP037205 MADE_1010220 99931b1c61101ee937673bc919d57529 45 PIRSF PIRSF037205 1 45 7.6E-24 T 13-10-2018 IPR017136 Uncharacterised conserved protein UCP037205 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 SUPERFAMILY SSF53623 109 357 1.31E-65 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 SUPERFAMILY SSF53244 359 511 1.3E-46 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 Pfam PF01225 Mur ligase family, catalytic domain 26 106 3.1E-13 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 23 510 3.2E-147 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 SUPERFAMILY SSF63418 13 107 1.31E-18 T 13-10-2018 IPR035911 MurE/MurF, N-terminal MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 Pfam PF08245 Mur ligase middle domain 118 338 6.9E-46 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 8 511 32.092 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 Gene3D G3DSA:3.90.190.20 370 516 1.3E-53 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 Pfam PF02875 Mur ligase family, glutamate ligase domain 359 444 1.7E-19 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 Gene3D G3DSA:3.40.1390.10 7 107 2.9E-25 T 13-10-2018 MADE_1015175 b3bd8edbe00d991fc722942a6ea00db9 516 Gene3D G3DSA:3.40.1190.10 109 362 2.0E-70 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 MADE_000001023450 358e6715d7f712e0a0d444074a1e42e3 340 SUPERFAMILY SSF56281 13 324 5.77E-64 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_000001023450 358e6715d7f712e0a0d444074a1e42e3 340 Gene3D G3DSA:3.60.15.10 19 172 9.3E-25 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_000001023450 358e6715d7f712e0a0d444074a1e42e3 340 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 8 335 8.4E-145 T 13-10-2018 IPR026360 Putative exonuclease, DNA ligase-associated MADE_000001023450 358e6715d7f712e0a0d444074a1e42e3 340 SMART SM00849 4 170 0.0065 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 9.8E-17 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.4E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.4E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.4E-6 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 SUPERFAMILY SSF53850 90 307 5.25E-37 T 13-10-2018 MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 Gene3D G3DSA:1.10.10.10 1 87 2.4E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 Gene3D G3DSA:3.40.190.10 90 304 1.9E-58 T 13-10-2018 MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 SUPERFAMILY SSF46785 2 83 7.35E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 Pfam PF03466 LysR substrate binding domain 97 304 2.0E-15 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1013060 4b383b2a2b026d43b719dca5b1a18125 314 Gene3D G3DSA:3.40.190.10 170 279 1.9E-58 T 13-10-2018 MADE_1003605 0dd3761da92f158099702c8d22cd07cf 341 PIRSF PIRSF004911 2 340 4.3E-113 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MADE_1003605 0dd3761da92f158099702c8d22cd07cf 341 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 16 335 5.6E-146 T 13-10-2018 IPR022462 Lysine-2,3-aminomutase-like MADE_1003605 0dd3761da92f158099702c8d22cd07cf 341 Pfam PF13353 4Fe-4S single cluster domain 111 184 5.0E-7 T 13-10-2018 MADE_1003605 0dd3761da92f158099702c8d22cd07cf 341 Pfam PF04055 Radical SAM superfamily 118 263 2.0E-10 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1003605 0dd3761da92f158099702c8d22cd07cf 341 Gene3D G3DSA:3.20.20.70 51 334 2.6E-88 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1003605 0dd3761da92f158099702c8d22cd07cf 341 SUPERFAMILY SSF102114 104 327 9.68E-26 T 13-10-2018 MADE_1003605 0dd3761da92f158099702c8d22cd07cf 341 TIGRFAM TIGR00238 TIGR00238: KamA family protein 3 328 2.5E-113 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase MADE_1013155 5a822f60477ba7be2a63b693b8863734 366 Gene3D G3DSA:3.40.50.2000 168 347 1.1E-63 T 13-10-2018 MADE_1013155 5a822f60477ba7be2a63b693b8863734 366 Gene3D G3DSA:3.40.50.2000 57 359 1.1E-63 T 13-10-2018 MADE_1013155 5a822f60477ba7be2a63b693b8863734 366 SUPERFAMILY SSF53756 6 364 1.79E-67 T 13-10-2018 MADE_1013155 5a822f60477ba7be2a63b693b8863734 366 Pfam PF13439 Glycosyltransferase Family 4 14 171 1.2E-25 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1013155 5a822f60477ba7be2a63b693b8863734 366 Pfam PF00534 Glycosyl transferases group 1 182 340 5.5E-25 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1010305 9612055967f750d2e1011bad0f134052 689 Pfam PF07715 TonB-dependent Receptor Plug Domain 55 162 4.1E-20 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1010305 9612055967f750d2e1011bad0f134052 689 Pfam PF00593 TonB dependent receptor 234 688 6.2E-48 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1010305 9612055967f750d2e1011bad0f134052 689 Gene3D G3DSA:2.40.170.20 174 689 1.9E-97 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1010305 9612055967f750d2e1011bad0f134052 689 Gene3D G3DSA:2.170.130.10 51 170 8.0E-23 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1010305 9612055967f750d2e1011bad0f134052 689 SUPERFAMILY SSF56935 39 689 2.88E-110 T 13-10-2018 MADE_1010305 9612055967f750d2e1011bad0f134052 689 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 672 689 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site MADE_1010835 152f4f95becd427624de036609dff4c4 154 PIRSF PIRSF000239 1 143 5.4E-19 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1010835 152f4f95becd427624de036609dff4c4 154 SUPERFAMILY SSF52833 4 153 7.49E-51 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1010835 152f4f95becd427624de036609dff4c4 154 Gene3D G3DSA:3.40.30.10 3 154 6.0E-49 T 13-10-2018 MADE_1010835 152f4f95becd427624de036609dff4c4 154 Pfam PF00578 AhpC/TSA family 7 134 7.4E-40 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1016105 c8282c8f964865baf10c66b303f49084 354 Gene3D G3DSA:1.25.40.10 47 230 1.5E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1016105 c8282c8f964865baf10c66b303f49084 354 SUPERFAMILY SSF81901 110 227 4.84E-6 T 13-10-2018 MADE_1019245 6d609df64cc4b732494f2a7a23d9af5d 172 Pfam PF00571 CBS domain 112 165 1.3E-9 T 13-10-2018 IPR000644 CBS domain MADE_1019245 6d609df64cc4b732494f2a7a23d9af5d 172 Pfam PF00571 CBS domain 17 70 8.5E-9 T 13-10-2018 IPR000644 CBS domain MADE_1019245 6d609df64cc4b732494f2a7a23d9af5d 172 Gene3D G3DSA:3.10.580.10 3 168 1.2E-28 T 13-10-2018 MADE_1019245 6d609df64cc4b732494f2a7a23d9af5d 172 SUPERFAMILY SSF54631 13 166 4.54E-25 T 13-10-2018 MADE_1019245 6d609df64cc4b732494f2a7a23d9af5d 172 SMART SM00116 119 166 0.004 T 13-10-2018 IPR000644 CBS domain MADE_1019245 6d609df64cc4b732494f2a7a23d9af5d 172 SMART SM00116 24 72 0.0024 T 13-10-2018 IPR000644 CBS domain MADE_1005925 724fdb48416540241d823c16a866bd31 768 Gene3D G3DSA:3.30.750.140 622 732 8.6E-31 T 13-10-2018 IPR038610 FliK-like, C-terminal domain superfamily MADE_1005925 724fdb48416540241d823c16a866bd31 768 Pfam PF02120 Flagellar hook-length control protein FliK 638 720 8.4E-23 T 13-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal MADE_1006605 94179eefbe02ae9ee7397e5874e3163b 386 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 80 375 2.8E-49 T 13-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MADE_1006605 94179eefbe02ae9ee7397e5874e3163b 386 Gene3D G3DSA:3.20.20.190 74 380 9.6E-87 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MADE_1006605 94179eefbe02ae9ee7397e5874e3163b 386 SUPERFAMILY SSF51695 74 381 1.12E-63 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MADE_1010055 b0e790b4c6591dbf38e7db1072092a18 279 Gene3D G3DSA:3.30.70.100 177 268 2.0E-26 T 13-10-2018 MADE_1010055 b0e790b4c6591dbf38e7db1072092a18 279 SUPERFAMILY SSF50182 110 175 2.81E-17 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1010055 b0e790b4c6591dbf38e7db1072092a18 279 SUPERFAMILY SSF82861 26 108 3.79E-16 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MADE_1010055 b0e790b4c6591dbf38e7db1072092a18 279 Pfam PF00924 Mechanosensitive ion channel 69 264 1.7E-49 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1010055 b0e790b4c6591dbf38e7db1072092a18 279 SUPERFAMILY SSF82689 178 275 1.1E-32 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1010055 b0e790b4c6591dbf38e7db1072092a18 279 Gene3D G3DSA:2.30.30.60 125 173 3.3E-19 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1010055 b0e790b4c6591dbf38e7db1072092a18 279 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 139 173 - T 13-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 MADE_1010505 0b4a0328c3bc9ce3d2237d767211150b 243 Pfam PF02146 Sir2 family 17 189 2.9E-48 T 13-10-2018 IPR003000 Sirtuin family GO:0070403 MADE_1010505 0b4a0328c3bc9ce3d2237d767211150b 243 Gene3D G3DSA:3.40.50.1220 12 231 3.5E-80 T 13-10-2018 MADE_1010505 0b4a0328c3bc9ce3d2237d767211150b 243 SUPERFAMILY SSF52467 10 237 1.05E-72 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MADE_1010505 0b4a0328c3bc9ce3d2237d767211150b 243 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 10 239 55.264 T 13-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 MADE_1010505 0b4a0328c3bc9ce3d2237d767211150b 243 Gene3D G3DSA:3.30.1600.10 26 161 3.5E-80 T 13-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily MADE_1007510 9054dc26c10de7b4c5516118b31940de 192 SUPERFAMILY SSF51161 71 191 7.07E-30 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1007510 9054dc26c10de7b4c5516118b31940de 192 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 140 172 2.4E-4 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1007510 9054dc26c10de7b4c5516118b31940de 192 Gene3D G3DSA:2.160.10.10 58 192 4.9E-34 T 13-10-2018 MADE_000001021750 1d1ac667b71f89bb76394b63bed0bba8 151 Pfam PF10263 SprT-like family 8 107 6.9E-16 T 13-10-2018 IPR006640 SprT-like MADE_000001021750 1d1ac667b71f89bb76394b63bed0bba8 151 SMART SM00731 4 151 1.4E-36 T 13-10-2018 IPR006640 SprT-like MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 Pfam PF06426 Serine acetyltransferase, N-terminal 11 113 9.2E-34 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 Gene3D G3DSA:2.160.10.10 144 265 4.5E-36 T 13-10-2018 MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 203 231 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 SMART SM00971 10 114 7.7E-51 T 13-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 83 243 3.3E-70 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 194 228 3.5E-9 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 Gene3D G3DSA:1.10.3130.10 2 143 3.3E-48 T 13-10-2018 MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 SUPERFAMILY SSF51161 10 250 5.68E-62 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1000990 d8013a162368419cf486ec79b0db09b4 268 PIRSF PIRSF000441 77 267 3.0E-60 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 MADE_1006990 e4ed9d68487795ca69c6b16cb6644406 291 Gene3D G3DSA:2.60.200.30 126 263 7.4E-94 T 13-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MADE_1006990 e4ed9d68487795ca69c6b16cb6644406 291 Hamap MF_00361 NAD kinase [nadK]. 4 286 33.24 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MADE_1006990 e4ed9d68487795ca69c6b16cb6644406 291 SUPERFAMILY SSF111331 5 288 5.49E-89 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MADE_1006990 e4ed9d68487795ca69c6b16cb6644406 291 Pfam PF01513 ATP-NAD kinase 5 270 6.5E-69 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MADE_1006990 e4ed9d68487795ca69c6b16cb6644406 291 Gene3D G3DSA:3.40.50.10330 22 286 7.4E-94 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 Gene3D G3DSA:3.30.540.10 4 153 2.4E-47 T 13-10-2018 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 Pfam PF00459 Inositol monophosphatase family 14 245 4.1E-47 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 9 262 4.6E-87 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 SUPERFAMILY SSF56655 7 250 1.57E-66 T 13-10-2018 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 Gene3D G3DSA:3.40.190.80 154 263 1.1E-32 T 13-10-2018 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 8 263 39.16 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 9.3E-7 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 9.3E-7 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1006730 9bee9dc5484b47e1e574467fb19b8b11 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 9.3E-7 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1019020 03f9dbb6cca75d4101b256a13015b038 982 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 164 9.6E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1019020 03f9dbb6cca75d4101b256a13015b038 982 SUPERFAMILY SSF56935 35 982 1.13E-83 T 13-10-2018 MADE_1019020 03f9dbb6cca75d4101b256a13015b038 982 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 43 982 1.7E-182 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_1019020 03f9dbb6cca75d4101b256a13015b038 982 Gene3D G3DSA:2.170.130.10 50 169 2.1E-18 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1019020 03f9dbb6cca75d4101b256a13015b038 982 Pfam PF00593 TonB dependent receptor 408 981 7.3E-32 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 Pfam PF00482 Type II secretion system (T2SS), protein F 272 394 7.3E-31 T 13-10-2018 IPR018076 Type II secretion system F domain MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 Pfam PF00482 Type II secretion system (T2SS), protein F 69 191 3.8E-31 T 13-10-2018 IPR018076 Type II secretion system F domain MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 Gene3D G3DSA:1.20.81.30 255 364 1.3E-29 T 13-10-2018 MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 Gene3D G3DSA:1.20.81.30 54 170 1.5E-28 T 13-10-2018 MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 5.6E-18 T 13-10-2018 IPR003004 GspF/PilC family MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 5.6E-18 T 13-10-2018 IPR003004 GspF/PilC family MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 5.6E-18 T 13-10-2018 IPR003004 GspF/PilC family MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 5.6E-18 T 13-10-2018 IPR003004 GspF/PilC family MADE_1015015 3a3b5bffaeb8ac51c50ac3eadd59623f 402 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 163 191 - T 13-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 MADE_000001022890 bf7c95047a8246cf227fdea5019714ed 206 SUPERFAMILY SSF55469 33 201 6.41E-38 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_000001022890 bf7c95047a8246cf227fdea5019714ed 206 Pfam PF00881 Nitroreductase family 34 184 2.2E-10 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MADE_000001022890 bf7c95047a8246cf227fdea5019714ed 206 Gene3D G3DSA:3.40.109.10 16 205 9.8E-25 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_000001022890 bf7c95047a8246cf227fdea5019714ed 206 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 7 206 41.534 T 13-10-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 MADE_1001030 7c404cf7e27da6117826436c931d64b7 172 Pfam PF01569 PAP2 superfamily 61 170 5.0E-23 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MADE_1001030 7c404cf7e27da6117826436c931d64b7 172 Gene3D G3DSA:1.20.144.10 87 172 1.1E-21 T 13-10-2018 MADE_1001030 7c404cf7e27da6117826436c931d64b7 172 SMART SM00014 59 168 4.4E-17 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MADE_1001030 7c404cf7e27da6117826436c931d64b7 172 SUPERFAMILY SSF48317 5 170 1.83E-40 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 Gene3D G3DSA:3.40.390.10 59 695 1.2E-223 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 594 605 2.5E-21 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 484 496 2.5E-21 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 523 539 2.5E-21 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 502 514 2.5E-21 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 SUPERFAMILY SSF55486 51 695 1.74E-196 T 13-10-2018 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 Pfam PF01431 Peptidase family M13 492 692 7.8E-66 T 13-10-2018 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 Pfam PF05649 Peptidase family M13 63 440 3.1E-93 T 13-10-2018 IPR008753 Peptidase M13, N-terminal domain GO:0006508 MADE_1006085 e5360296a3bf11998022fe21f1231da1 695 Gene3D G3DSA:1.10.1380.10 89 479 1.2E-223 T 13-10-2018 MADE_1016520 dabc81a8e33293a74404adc7e85f8aca 824 Gene3D G3DSA:3.40.50.720 1 347 3.1E-35 T 13-10-2018 MADE_1016520 dabc81a8e33293a74404adc7e85f8aca 824 SUPERFAMILY SSF51735 7 357 3.71E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1016520 dabc81a8e33293a74404adc7e85f8aca 824 Pfam PF07884 Vitamin K epoxide reductase family 520 654 1.4E-19 T 13-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 MADE_1016520 dabc81a8e33293a74404adc7e85f8aca 824 Gene3D G3DSA:1.20.1440.130 510 661 7.9E-13 T 13-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 MADE_1016520 dabc81a8e33293a74404adc7e85f8aca 824 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 234 2.0E-18 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 442 2.3E-218 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 SMART SM00382 49 331 7.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 Gene3D G3DSA:1.10.8.60 334 439 8.5E-40 T 13-10-2018 MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 Pfam PF07724 AAA domain (Cdc48 subfamily) 172 328 1.1E-41 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 442 43.324 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 SMART SM01086 334 430 4.7E-21 T 13-10-2018 IPR019489 Clp ATPase, C-terminal MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 103 9.4E-7 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_1018285 ae97e04494b07a1c79300eb502bf6f04 442 SUPERFAMILY SSF52540 3 440 3.09E-90 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1016785 e94ec74284619d4a9ddb4548e20ed70c 294 Pfam PF00589 Phage integrase family 209 273 1.9E-8 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1016785 e94ec74284619d4a9ddb4548e20ed70c 294 Gene3D G3DSA:1.10.443.10 198 287 2.9E-11 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1016785 e94ec74284619d4a9ddb4548e20ed70c 294 SUPERFAMILY SSF56349 87 271 2.26E-14 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1005710 b8eb31df53959fb1aa0d32b0e11b9e65 140 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 138 1.1E-46 T 13-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 MADE_1005710 b8eb31df53959fb1aa0d32b0e11b9e65 140 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 13-10-2018 IPR019776 Flagellar basal body rod protein, conserved site MADE_1005710 b8eb31df53959fb1aa0d32b0e11b9e65 140 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 91 136 3.9E-11 T 13-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain MADE_1005710 b8eb31df53959fb1aa0d32b0e11b9e65 140 Pfam PF00460 Flagella basal body rod protein 7 32 9.6E-6 T 13-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 MADE_1004155 c62135d7ef220b9a4b99b5ce05dee86e 157 PIRSF PIRSF005276 1 157 4.1E-52 T 13-10-2018 IPR007481 Stringent starvation protein B MADE_1004155 c62135d7ef220b9a4b99b5ce05dee86e 157 Pfam PF04386 Stringent starvation protein B 7 157 3.6E-37 T 13-10-2018 IPR007481 Stringent starvation protein B MADE_1004155 c62135d7ef220b9a4b99b5ce05dee86e 157 Gene3D G3DSA:2.30.30.220 1 126 2.0E-48 T 13-10-2018 IPR036760 SspB-like superfamily MADE_1004155 c62135d7ef220b9a4b99b5ce05dee86e 157 SUPERFAMILY SSF101738 1 112 9.81E-43 T 13-10-2018 IPR036760 SspB-like superfamily MADE_000001023035 3623781a3722519a59eccd005b9352c1 1057 Pfam PF13620 Carboxypeptidase regulatory-like domain 34 114 5.9E-15 T 13-10-2018 MADE_000001023035 3623781a3722519a59eccd005b9352c1 1057 Pfam PF07715 TonB-dependent Receptor Plug Domain 137 238 4.4E-5 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_000001023035 3623781a3722519a59eccd005b9352c1 1057 SUPERFAMILY SSF56935 113 1010 3.22E-61 T 13-10-2018 MADE_000001023035 3623781a3722519a59eccd005b9352c1 1057 SUPERFAMILY SSF49452 26 113 1.71E-7 T 13-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 MADE_000001023035 3623781a3722519a59eccd005b9352c1 1057 Gene3D G3DSA:2.60.40.1120 33 115 1.0E-5 T 13-10-2018 MADE_1000190 bb097f2e30eb798c43fb529e85eecb18 484 Gene3D G3DSA:2.30.40.20 53 89 1.7E-8 T 13-10-2018 MADE_1000190 bb097f2e30eb798c43fb529e85eecb18 484 SUPERFAMILY SSF56672 39 247 1.25E-42 T 13-10-2018 MADE_1000190 bb097f2e30eb798c43fb529e85eecb18 484 Gene3D G3DSA:3.30.70.270 90 187 1.7E-8 T 13-10-2018 MADE_1000190 bb097f2e30eb798c43fb529e85eecb18 484 Gene3D G3DSA:1.10.150.20 188 236 1.7E-8 T 13-10-2018 MADE_1000190 bb097f2e30eb798c43fb529e85eecb18 484 Pfam PF00817 impB/mucB/samB family 37 145 2.3E-6 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MADE_000001022875 bf710dc3f96a2a75ca1a42f8f4c33b92 772 Pfam PF00593 TonB dependent receptor 309 769 6.6E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_000001022875 bf710dc3f96a2a75ca1a42f8f4c33b92 772 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 152 2.9E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_000001022875 bf710dc3f96a2a75ca1a42f8f4c33b92 772 Gene3D G3DSA:2.40.170.20 301 772 2.8E-74 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_000001022875 bf710dc3f96a2a75ca1a42f8f4c33b92 772 Gene3D G3DSA:2.40.170.20 37 293 1.9E-48 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_000001022875 bf710dc3f96a2a75ca1a42f8f4c33b92 772 SUPERFAMILY SSF56935 22 772 1.26E-100 T 13-10-2018 MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 SMART SM00448 4 114 8.2E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 Pfam PF00072 Response regulator receiver domain 6 113 9.8E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 SMART SM00862 153 229 2.2E-19 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 SUPERFAMILY SSF52172 2 124 1.28E-35 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 2.3E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 Gene3D G3DSA:3.40.50.2300 1 122 1.1E-32 T 13-10-2018 MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 SUPERFAMILY SSF46894 133 230 6.24E-23 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1001355 f65a985184b5d25037a9af4b19ecff32 235 Gene3D G3DSA:1.10.10.10 123 233 2.3E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 8 30 8.6E-36 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 300 321 8.6E-36 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 206 224 8.6E-36 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 226 243 8.6E-36 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 270 285 8.6E-36 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 SUPERFAMILY SSF160544 249 352 1.31E-37 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 6 351 3.8E-119 T 13-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 Gene3D G3DSA:3.40.1690.10 215 356 1.1E-53 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MADE_1005965 60c4e90323b04292d80fa07eb75e528d 374 Pfam PF01312 FlhB HrpN YscU SpaS Family 5 345 6.6E-116 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MADE_1004570 ff0341f4f872cb119c6823ebf040337d 192 Pfam PF13505 Outer membrane protein beta-barrel domain 10 175 1.2E-12 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel MADE_1004570 ff0341f4f872cb119c6823ebf040337d 192 SUPERFAMILY SSF56925 29 151 5.1E-13 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MADE_1004570 ff0341f4f872cb119c6823ebf040337d 192 Gene3D G3DSA:2.40.160.20 20 192 9.1E-8 T 13-10-2018 MADE_1020035 3a4e62dc93a776e9be5aeb0054e8d51b 231 SUPERFAMILY SSF53681 118 229 7.46E-33 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MADE_1020035 3a4e62dc93a776e9be5aeb0054e8d51b 231 SUPERFAMILY SSF53681 1 114 2.65E-35 T 13-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MADE_1020035 3a4e62dc93a776e9be5aeb0054e8d51b 231 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 2.6E-60 T 13-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 MADE_1020035 3a4e62dc93a776e9be5aeb0054e8d51b 231 TIGRFAM TIGR00035 asp_race: aspartate racemase 2 230 1.6E-66 T 13-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 MADE_1020035 3a4e62dc93a776e9be5aeb0054e8d51b 231 Gene3D G3DSA:3.40.50.1860 4 224 5.9E-82 T 13-10-2018 MADE_1020035 3a4e62dc93a776e9be5aeb0054e8d51b 231 Gene3D G3DSA:3.40.50.1860 104 215 5.9E-82 T 13-10-2018 MADE_1008925 17375768c16aa91d6c12ce202517732f 133 Gene3D G3DSA:3.30.300.20 1 108 1.2E-31 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1008925 17375768c16aa91d6c12ce202517732f 133 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 6 113 24.31 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MADE_1008925 17375768c16aa91d6c12ce202517732f 133 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 13-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 MADE_1008925 17375768c16aa91d6c12ce202517732f 133 Pfam PF02033 Ribosome-binding factor A 7 112 5.8E-28 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MADE_1008925 17375768c16aa91d6c12ce202517732f 133 SUPERFAMILY SSF89919 3 115 3.79E-29 T 13-10-2018 IPR023799 Ribosome-binding factor A domain superfamily MADE_1008925 17375768c16aa91d6c12ce202517732f 133 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 5.8E-31 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MADE_1008925 17375768c16aa91d6c12ce202517732f 133 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 3.0E-21 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 MADE_1004140 20cd8f4cfa1bfa28c98836869e1eb4d7 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.354 T 13-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid MADE_1004140 20cd8f4cfa1bfa28c98836869e1eb4d7 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 5.0E-44 T 13-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 MADE_1004140 20cd8f4cfa1bfa28c98836869e1eb4d7 130 SUPERFAMILY SSF54211 6 130 1.29E-45 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1004140 20cd8f4cfa1bfa28c98836869e1eb4d7 130 Gene3D G3DSA:3.30.230.10 1 130 1.1E-51 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_1007245 40b852f958955954471242ee79255894 173 Pfam PF11157 Protein of unknown function (DUF2937) 3 160 1.2E-41 T 13-10-2018 IPR022584 Protein of unknown function DUF2937 MADE_1019125 c3d520b0f6723d693a5493c38adfcfd5 406 PRINTS PR01035 Tetracycline resistance protein signature 348 371 1.4E-8 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MADE_1019125 c3d520b0f6723d693a5493c38adfcfd5 406 PRINTS PR01035 Tetracycline resistance protein signature 20 36 1.4E-8 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MADE_1019125 c3d520b0f6723d693a5493c38adfcfd5 406 PRINTS PR01035 Tetracycline resistance protein signature 175 195 1.4E-8 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MADE_1019125 c3d520b0f6723d693a5493c38adfcfd5 406 PRINTS PR01035 Tetracycline resistance protein signature 147 169 1.4E-8 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MADE_1019125 c3d520b0f6723d693a5493c38adfcfd5 406 SUPERFAMILY SSF103473 10 402 2.35E-44 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1019125 c3d520b0f6723d693a5493c38adfcfd5 406 Pfam PF07690 Major Facilitator Superfamily 14 307 2.3E-27 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1019125 c3d520b0f6723d693a5493c38adfcfd5 406 Gene3D G3DSA:1.20.1250.20 6 400 1.3E-43 T 13-10-2018 MADE_1009150 b17ef3279f2522f19036a84d84bc030a 480 Pfam PF12698 ABC-2 family transporter protein 133 254 5.4E-9 T 13-10-2018 MADE_1009150 b17ef3279f2522f19036a84d84bc030a 480 SUPERFAMILY SSF103473 26 259 1.28E-5 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1009150 b17ef3279f2522f19036a84d84bc030a 480 Pfam PF12040 Domain of unknown function (DUF3526) 274 441 6.7E-39 T 13-10-2018 IPR021913 Protein of unknown function DUF3526 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SMART SM00388 576 641 7.1E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SMART SM00448 827 943 1.2E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SMART SM00086 515 556 9.6E-6 T 13-10-2018 IPR001610 PAC motif MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SUPERFAMILY SSF55874 630 800 1.26E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Gene3D G3DSA:3.30.565.10 642 808 1.6E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Pfam PF13426 PAS domain 463 555 7.6E-20 T 13-10-2018 IPR000014 PAS domain MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Gene3D G3DSA:1.10.287.130 567 641 3.7E-23 T 13-10-2018 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 445 562 3.0E-19 T 13-10-2018 IPR000014 PAS domain MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SUPERFAMILY SSF55785 450 556 8.2E-24 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Gene3D G3DSA:3.30.450.20 320 440 2.7E-6 T 13-10-2018 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Pfam PF00072 Response regulator receiver domain 829 943 2.1E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 688 803 1.4E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Pfam PF00512 His Kinase A (phospho-acceptor) domain 577 641 6.1E-18 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SMART SM00387 688 804 1.9E-35 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Gene3D G3DSA:3.30.450.20 441 566 1.1E-38 T 13-10-2018 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SUPERFAMILY SSF52172 826 946 1.18E-35 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 PRINTS PR00344 Bacterial sensor protein C-terminal signature 729 743 1.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 PRINTS PR00344 Bacterial sensor protein C-terminal signature 788 801 1.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 PRINTS PR00344 Bacterial sensor protein C-terminal signature 764 782 1.4E-11 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 Gene3D G3DSA:3.40.50.12740 826 958 5.6E-41 T 13-10-2018 MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SMART SM00091 440 509 0.002 T 13-10-2018 IPR000014 PAS domain MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SMART SM00091 333 401 5.9 T 13-10-2018 IPR000014 PAS domain MADE_1004320 96c26cd3feb8ca0e4b1c3e8a5e08c3e7 959 SUPERFAMILY SSF47384 561 642 1.06E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1006705 f39f87295475f4e8cce16bd28f1ac930 555 SUPERFAMILY SSF53187 46 541 8.14E-67 T 13-10-2018 MADE_1006705 f39f87295475f4e8cce16bd28f1ac930 555 SUPERFAMILY SSF52025 144 248 5.23E-7 T 13-10-2018 MADE_1006705 f39f87295475f4e8cce16bd28f1ac930 555 Gene3D G3DSA:3.50.30.30 113 303 4.0E-53 T 13-10-2018 MADE_1006705 f39f87295475f4e8cce16bd28f1ac930 555 Gene3D G3DSA:3.40.630.10 69 512 4.0E-53 T 13-10-2018 MADE_1006705 f39f87295475f4e8cce16bd28f1ac930 555 Pfam PF04389 Peptidase family M28 312 526 1.5E-45 T 13-10-2018 IPR007484 Peptidase M28 MADE_1006705 f39f87295475f4e8cce16bd28f1ac930 555 Pfam PF02225 PA domain 147 238 7.5E-8 T 13-10-2018 IPR003137 PA domain MADE_1001040 8be719efbf9cc6f99057661160fe5869 268 SUPERFAMILY SSF48537 28 263 9.29E-59 T 13-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 MADE_1001040 8be719efbf9cc6f99057661160fe5869 268 Gene3D G3DSA:1.10.575.10 28 268 6.6E-64 T 13-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 MADE_1001040 8be719efbf9cc6f99057661160fe5869 268 Pfam PF02265 S1/P1 Nuclease 28 265 2.0E-65 T 13-10-2018 IPR003154 S1/P1 nuclease GO:0003676|GO:0004519|GO:0006308 MADE_1002880 05952080499a2ec1ceb13eba50c991dc 164 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 4 157 31.289 T 13-10-2018 IPR033747 Class I PurE MADE_1002880 05952080499a2ec1ceb13eba50c991dc 164 Gene3D G3DSA:3.40.50.7700 1 162 2.8E-70 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MADE_1002880 05952080499a2ec1ceb13eba50c991dc 164 SMART SM01001 2 153 3.5E-98 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MADE_1002880 05952080499a2ec1ceb13eba50c991dc 164 Pfam PF00731 AIR carboxylase 3 151 7.6E-63 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MADE_1002880 05952080499a2ec1ceb13eba50c991dc 164 SUPERFAMILY SSF52255 3 160 1.07E-63 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 MADE_1002880 05952080499a2ec1ceb13eba50c991dc 164 PIRSF PIRSF001338 1 164 1.5E-67 T 13-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 MADE_1002880 05952080499a2ec1ceb13eba50c991dc 164 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 4 160 2.3E-62 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 MADE_1009675 6eecf20e66eb8a414e1ef05bbe0a0ee9 72 Gene3D G3DSA:1.10.3390.10 1 72 1.2E-28 T 13-10-2018 IPR023202 YejL-like superfamily MADE_1009675 6eecf20e66eb8a414e1ef05bbe0a0ee9 72 PIRSF PIRSF006188 1 72 1.0E-25 T 13-10-2018 IPR009857 Uncharacterised protein family UPF0352 MADE_1009675 6eecf20e66eb8a414e1ef05bbe0a0ee9 72 SUPERFAMILY SSF158651 1 71 4.06E-27 T 13-10-2018 IPR023202 YejL-like superfamily MADE_1009675 6eecf20e66eb8a414e1ef05bbe0a0ee9 72 Pfam PF07208 Protein of unknown function (DUF1414) 28 69 4.3E-21 T 13-10-2018 IPR009857 Uncharacterised protein family UPF0352 MADE_1009675 6eecf20e66eb8a414e1ef05bbe0a0ee9 72 ProDom PD027794 UPF0352 YEJL NTHI1007 CPS_2611 VF1649 VV1166 HD1515 VP2129 YPO1261/Y2923/YP0880 ECA2748 1 69 2.0E-14 T 13-10-2018 IPR009857 Uncharacterised protein family UPF0352 MADE_1002905 56f5db23effffbeb057147c3188eaee9 704 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 213 304 3.0E-10 T 13-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 MADE_1002905 56f5db23effffbeb057147c3188eaee9 704 SUPERFAMILY SSF53474 451 697 1.01E-63 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1002905 56f5db23effffbeb057147c3188eaee9 704 Gene3D G3DSA:3.40.50.1820 415 698 7.7E-65 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1002905 56f5db23effffbeb057147c3188eaee9 704 Pfam PF00326 Prolyl oligopeptidase family 490 698 1.2E-51 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MADE_1002905 56f5db23effffbeb057147c3188eaee9 704 Gene3D G3DSA:2.120.10.30 209 316 1.6E-17 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1002905 56f5db23effffbeb057147c3188eaee9 704 Gene3D G3DSA:2.120.10.30 38 208 4.6E-15 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1002905 56f5db23effffbeb057147c3188eaee9 704 SUPERFAMILY SSF82171 60 434 2.49E-44 T 13-10-2018 MADE_1014515 fa83d94ba9e5fe0e757de7df9ef12200 137 Pfam PF08291 Peptidase M15 10 123 3.1E-5 T 13-10-2018 IPR013230 Peptidase M15A, C-terminal KEGG: 00550+3.4.17.14|MetaCyc: PWY-6470 MADE_1014515 fa83d94ba9e5fe0e757de7df9ef12200 137 SUPERFAMILY SSF55166 7 126 7.77E-14 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MADE_1015245 e52e13beddf3fc701fa343f31b07ca55 346 SUPERFAMILY SSF53474 80 293 8.04E-25 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1015245 e52e13beddf3fc701fa343f31b07ca55 346 Gene3D G3DSA:3.40.50.1820 71 306 8.3E-31 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1015245 e52e13beddf3fc701fa343f31b07ca55 346 Pfam PF12146 Serine aminopeptidase, S33 82 216 1.4E-11 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 MADE_1002335 f24b61c1557ad65779d7634fdceabb03 436 Gene3D G3DSA:3.40.50.11720 49 226 2.4E-38 T 13-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MADE_1002335 f24b61c1557ad65779d7634fdceabb03 436 Gene3D G3DSA:3.40.50.2000 241 419 1.8E-56 T 13-10-2018 MADE_1002335 f24b61c1557ad65779d7634fdceabb03 436 Pfam PF00534 Glycosyl transferases group 1 263 415 1.4E-6 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1002335 f24b61c1557ad65779d7634fdceabb03 436 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 51 228 7.7E-56 T 13-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 MADE_1002335 f24b61c1557ad65779d7634fdceabb03 436 SUPERFAMILY SSF53756 97 419 1.88E-8 T 13-10-2018 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 PIRSF PIRSF004491 2 306 1.1E-105 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 Pfam PF01687 Riboflavin kinase 184 303 1.3E-35 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 SMART SM00904 183 306 1.5E-60 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 305 1.9E-102 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 Pfam PF06574 FAD synthetase 12 167 2.4E-58 T 13-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 Gene3D G3DSA:3.40.50.620 1 186 3.0E-63 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 SUPERFAMILY SSF82114 174 305 8.5E-45 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 Gene3D G3DSA:2.40.30.30 188 306 3.7E-39 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 MADE_1012670 c60ea0c20708a815c1a854458611d10d 306 SUPERFAMILY SSF52374 15 175 1.77E-36 T 13-10-2018 MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 SUPERFAMILY SSF53271 250 481 4.86E-69 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 SUPERFAMILY SSF56235 2 257 1.54E-70 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 464 44.87 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 Pfam PF00156 Phosphoribosyl transferase domain 280 392 8.8E-8 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 Gene3D G3DSA:3.60.20.10 2 412 3.3E-155 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 Gene3D G3DSA:3.40.50.2020 277 441 3.3E-155 T 13-10-2018 MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 464 6.2E-157 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 Pfam PF13522 Glutamine amidotransferase domain 64 208 3.2E-17 T 13-10-2018 MADE_1009930 97d1123fc924d013c818e554b63bbad7 507 PIRSF PIRSF000485 1 481 3.0E-166 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 MADE_1000540 4f1632c0a606464e9c85e5c11acc021f 362 Pfam PF04245 37-kD nucleoid-associated bacterial protein 13 322 8.7E-15 T 13-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 158 171 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 Gene3D G3DSA:1.10.10.60 375 437 4.8E-15 T 13-10-2018 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 Gene3D G3DSA:1.10.8.60 305 374 2.6E-22 T 13-10-2018 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 SUPERFAMILY SSF46689 343 437 5.08E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 Pfam PF00072 Response regulator receiver domain 4 112 3.5E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 345 354 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_1011545 5f6815497d4149328057253b5996a2ff 443 SUPERFAMILY SSF52172 2 178 1.11E-30 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1011545 5f6815497d4149328057253b5996a2ff 443 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 219 234 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 Gene3D G3DSA:3.40.50.2300 3 119 3.5E-22 T 13-10-2018 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 402 419 2.6E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 419 439 2.6E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 SMART SM00448 2 113 2.9E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 Gene3D G3DSA:3.40.50.300 120 304 3.1E-59 T 13-10-2018 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 Pfam PF00158 Sigma-54 interaction domain 134 299 8.9E-63 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 Pfam PF02954 Bacterial regulatory protein, Fis family 396 436 1.7E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1011545 5f6815497d4149328057253b5996a2ff 443 SMART SM00382 154 296 3.0E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1011545 5f6815497d4149328057253b5996a2ff 443 SUPERFAMILY SSF52540 134 366 9.52E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006245 a7c45888d1c8fe745ede66e2a9310acc 184 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 95 177 1.3E-8 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MADE_1006245 a7c45888d1c8fe745ede66e2a9310acc 184 Gene3D G3DSA:2.60.120.620 4 182 1.4E-14 T 13-10-2018 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 SUPERFAMILY SSF63380 3 114 5.25E-19 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 121 140 2.1E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 41 51 2.1E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 60 67 2.1E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 159 170 2.1E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 SUPERFAMILY SSF54292 227 327 3.8E-15 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 Gene3D G3DSA:3.40.50.80 112 234 1.4E-19 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 SUPERFAMILY SSF52343 102 226 3.01E-23 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 Pfam PF00970 Oxidoreductase FAD-binding domain 24 113 6.1E-10 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 Gene3D G3DSA:2.40.30.10 9 109 3.5E-14 T 13-10-2018 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 PRINTS PR00409 Phthalate dioxygenase reductase family signature 121 140 7.9E-6 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 PRINTS PR00409 Phthalate dioxygenase reductase family signature 201 209 7.9E-6 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 PRINTS PR00409 Phthalate dioxygenase reductase family signature 99 113 7.9E-6 T 13-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 Pfam PF00175 Oxidoreductase NAD-binding domain 122 215 2.1E-10 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MADE_1006455 aca455c6414c8e11115140f8ed2281a8 327 Gene3D G3DSA:3.10.20.30 235 327 2.2E-11 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 SMART SM00487 23 220 7.8E-61 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 Pfam PF03880 DbpA RNA binding domain 389 457 7.7E-22 T 13-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 Pfam PF00270 DEAD/DEAH box helicase 29 194 1.4E-49 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 SMART SM00490 256 337 1.4E-25 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 SUPERFAMILY SSF52540 73 357 4.64E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 Pfam PF00271 Helicase conserved C-terminal domain 231 337 1.2E-25 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 Gene3D G3DSA:3.30.70.330 387 459 5.3E-21 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 Gene3D G3DSA:3.40.50.300 214 373 2.4E-43 T 13-10-2018 MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 Gene3D G3DSA:3.40.50.300 1 213 6.9E-75 T 13-10-2018 MADE_000001023375 4d057630e20586f6f988452929fc52c7 459 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MADE_1003650 29f39a5017213683e2a7a5a54e29e468 410 Gene3D G3DSA:3.40.50.150 219 410 1.1E-44 T 13-10-2018 MADE_1003650 29f39a5017213683e2a7a5a54e29e468 410 PIRSF PIRSF037565 1 410 2.5E-133 T 13-10-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 MADE_1003650 29f39a5017213683e2a7a5a54e29e468 410 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 2 409 47.603 T 13-10-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 MADE_1003650 29f39a5017213683e2a7a5a54e29e468 410 SUPERFAMILY SSF53335 232 393 3.87E-24 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1003650 29f39a5017213683e2a7a5a54e29e468 410 Gene3D G3DSA:3.40.50.150 8 208 7.3E-53 T 13-10-2018 MADE_1003650 29f39a5017213683e2a7a5a54e29e468 410 Pfam PF05175 Methyltransferase small domain 232 405 5.6E-45 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MADE_1003650 29f39a5017213683e2a7a5a54e29e468 410 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 338 344 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1000115 a783d9194d41577db5c640328729a053 369 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 76 289 3.8E-76 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MADE_1000115 a783d9194d41577db5c640328729a053 369 Gene3D G3DSA:3.40.50.450 2 292 6.3E-95 T 13-10-2018 MADE_1000115 a783d9194d41577db5c640328729a053 369 SUPERFAMILY SSF102405 83 287 5.72E-41 T 13-10-2018 MADE_1000115 a783d9194d41577db5c640328729a053 369 Pfam PF02481 DNA recombination-mediator protein A 78 281 8.5E-76 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MADE_1005795 03f0da5cd387ea9b810db58796f76089 700 Pfam PF01973 Protein of unknown function DUF115 305 464 4.9E-28 T 13-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like MADE_000001020900 af83fea6ca698620b8f89511e30590a4 411 Pfam PF13700 Domain of unknown function (DUF4158) 18 94 1.2E-12 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 Pfam PF16124 RecQ zinc-binding 544 591 9.6E-8 T 13-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 SMART SM00490 242 323 3.7E-27 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 SMART SM00487 13 209 4.4E-25 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 Gene3D G3DSA:3.40.50.300 1 199 1.7E-66 T 13-10-2018 MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 Pfam PF00270 DEAD/DEAH box helicase 20 181 1.3E-17 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 SUPERFAMILY SSF52540 58 336 7.63E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 Gene3D G3DSA:3.40.50.300 201 408 8.3E-45 T 13-10-2018 MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 Gene3D G3DSA:1.10.10.10 523 677 2.1E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 347 3.8E-112 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 132 141 - T 13-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site MADE_1014215 dc3869e104fff8e68f3945bd11daddba 679 Pfam PF00271 Helicase conserved C-terminal domain 216 322 1.8E-18 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1014225 c1f4325cddd63cd46d877586db1a9167 275 SUPERFAMILY SSF53790 3 246 8.9E-27 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 MADE_1014225 c1f4325cddd63cd46d877586db1a9167 275 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 216 6.5E-25 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 MADE_1014225 c1f4325cddd63cd46d877586db1a9167 275 Gene3D G3DSA:3.40.1010.10 1 126 1.2E-17 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 MADE_1006665 bc1141c03babe146d64d2f49e138caa7 460 Pfam PF01554 MatE 28 188 1.7E-25 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_1006665 bc1141c03babe146d64d2f49e138caa7 460 Pfam PF01554 MatE 253 411 1.2E-19 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_1006665 bc1141c03babe146d64d2f49e138caa7 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 421 1.4E-56 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_1006665 bc1141c03babe146d64d2f49e138caa7 460 PIRSF PIRSF006603 3 453 7.0E-110 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_000001022695 a1010bcd6aa92d413c2b6021eff47e54 275 SUPERFAMILY SSF51126 30 258 5.66E-60 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor MADE_000001022695 a1010bcd6aa92d413c2b6021eff47e54 275 Gene3D G3DSA:2.160.20.10 29 269 3.9E-77 T 13-10-2018 IPR012334 Pectin lyase fold MADE_000001022695 a1010bcd6aa92d413c2b6021eff47e54 275 Pfam PF14592 Chondroitinase B 30 257 4.2E-83 T 13-10-2018 IPR039513 PL-6 family MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 18 29 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 Gene3D G3DSA:3.20.20.70 1 324 2.7E-81 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 SMART SM00729 12 215 1.1E-4 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 3 324 3.9E-100 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 Pfam PF13353 4Fe-4S single cluster domain 21 118 9.6E-7 T 13-10-2018 MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 Pfam PF06463 Molybdenum Cofactor Synthesis C 184 307 2.0E-32 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 SUPERFAMILY SSF102114 3 277 5.49E-69 T 13-10-2018 MADE_1019350 4181a2d82a5141cdfa65dbe1af3347b2 324 Pfam PF04055 Radical SAM superfamily 17 176 6.7E-25 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1016005 338f5fbce88c9d04a2509374f48a630c 379 Pfam PF13487 HD domain 260 321 4.2E-15 T 13-10-2018 MADE_1016005 338f5fbce88c9d04a2509374f48a630c 379 Gene3D G3DSA:1.10.3210.10 189 375 4.0E-42 T 13-10-2018 MADE_1016005 338f5fbce88c9d04a2509374f48a630c 379 SMART SM00073 10 107 3.2E-12 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1016005 338f5fbce88c9d04a2509374f48a630c 379 Pfam PF01627 Hpt domain 13 104 5.6E-8 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1016005 338f5fbce88c9d04a2509374f48a630c 379 SUPERFAMILY SSF109604 196 368 6.6E-19 T 13-10-2018 MADE_1016005 338f5fbce88c9d04a2509374f48a630c 379 Gene3D G3DSA:1.20.120.160 5 144 2.6E-24 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1016005 338f5fbce88c9d04a2509374f48a630c 379 SUPERFAMILY SSF47226 12 123 7.07E-20 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1005755 d368aa6f78d43b17dfac929072c9c5bb 404 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 3.7E-27 T 13-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 MADE_1005755 d368aa6f78d43b17dfac929072c9c5bb 404 SUPERFAMILY SSF64518 1 404 1.03E-76 T 13-10-2018 MADE_1005755 d368aa6f78d43b17dfac929072c9c5bb 404 Gene3D G3DSA:1.20.1330.10 40 256 2.1E-46 T 13-10-2018 MADE_1005755 d368aa6f78d43b17dfac929072c9c5bb 404 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 404 8.4E-85 T 13-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 MADE_1005755 d368aa6f78d43b17dfac929072c9c5bb 404 Gene3D G3DSA:1.20.1330.10 263 379 1.0E-7 T 13-10-2018 MADE_1005660 215ef794a6d847925da5b6aea28ae722 94 Gene3D G3DSA:3.20.20.450 1 85 6.7E-15 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1005660 215ef794a6d847925da5b6aea28ae722 94 SUPERFAMILY SSF141868 2 80 2.22E-14 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1005660 215ef794a6d847925da5b6aea28ae722 94 Pfam PF00563 EAL domain 2 81 4.3E-14 T 13-10-2018 IPR001633 EAL domain MADE_1008890 630d2848d0a7a7264cdc69f4330d0589 901 Pfam PF00593 TonB dependent receptor 360 898 8.9E-41 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1008890 630d2848d0a7a7264cdc69f4330d0589 901 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 177 5.7E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1008890 630d2848d0a7a7264cdc69f4330d0589 901 Gene3D G3DSA:2.170.130.10 37 181 1.4E-28 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1008890 630d2848d0a7a7264cdc69f4330d0589 901 SUPERFAMILY SSF56935 45 901 1.16E-89 T 13-10-2018 MADE_1000170 ae2a2045b2080147c66434e42bf7d8e9 269 Gene3D G3DSA:3.40.190.10 114 205 4.7E-11 T 13-10-2018 MADE_1000170 ae2a2045b2080147c66434e42bf7d8e9 269 Gene3D G3DSA:3.40.190.10 34 241 4.7E-11 T 13-10-2018 MADE_1000170 ae2a2045b2080147c66434e42bf7d8e9 269 SUPERFAMILY SSF53850 19 242 2.08E-16 T 13-10-2018 MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 Pfam PF00270 DEAD/DEAH box helicase 26 193 1.0E-47 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 Gene3D G3DSA:3.40.50.300 213 426 4.9E-49 T 13-10-2018 MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 SUPERFAMILY SSF52540 72 358 4.73E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 SMART SM00487 20 221 5.5E-61 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 Pfam PF00271 Helicase conserved C-terminal domain 230 338 1.9E-27 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 Gene3D G3DSA:3.40.50.300 1 209 1.8E-76 T 13-10-2018 MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 SMART SM00490 257 338 3.8E-32 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1016435 0dd0176f5fcfaba19f96b057f3a0aadc 480 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MADE_1008220 24bc8c751ab27f87896649e33623dba9 249 SMART SM00382 100 226 2.2E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1008220 24bc8c751ab27f87896649e33623dba9 249 Gene3D G3DSA:3.40.50.300 63 249 4.1E-47 T 13-10-2018 MADE_1008220 24bc8c751ab27f87896649e33623dba9 249 SUPERFAMILY SSF52540 85 231 8.85E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008220 24bc8c751ab27f87896649e33623dba9 249 Pfam PF01695 IstB-like ATP binding protein 55 232 2.2E-57 T 13-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 MADE_1008220 24bc8c751ab27f87896649e33623dba9 249 PIRSF PIRSF003073 1 249 5.6E-82 T 13-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 12 580 6.1E-224 T 13-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 SUPERFAMILY SSF52540 330 578 1.81E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 Gene3D G3DSA:1.20.1560.10 1 326 2.9E-78 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 Pfam PF00005 ABC transporter 357 507 9.9E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 Pfam PF00664 ABC transporter transmembrane region 36 288 5.8E-51 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 SMART SM00382 366 553 1.0E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 Gene3D G3DSA:3.40.50.300 327 579 1.5E-94 T 13-10-2018 MADE_000001022000 3c6c971e0a6d13fb44dedcbb4c76cbbd 582 SUPERFAMILY SSF90123 8 324 1.1E-73 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001021860 44d7ebd74227635c2ab07294a228e207 245 SUPERFAMILY SSF53474 2 243 8.58E-47 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001021860 44d7ebd74227635c2ab07294a228e207 245 Pfam PF00561 alpha/beta hydrolase fold 2 233 1.8E-18 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_000001021860 44d7ebd74227635c2ab07294a228e207 245 Gene3D G3DSA:3.40.50.1820 1 245 8.6E-67 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1016635 d9e12bc6783c5f5a8d5e586633f21718 273 Pfam PF01925 Sulfite exporter TauE/SafE 13 267 2.2E-40 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 Pfam PF03466 LysR substrate binding domain 89 282 5.5E-21 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 Gene3D G3DSA:3.40.190.10 117 275 3.0E-16 T 13-10-2018 MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 Gene3D G3DSA:1.10.10.10 2 85 4.0E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.9E-21 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 SUPERFAMILY SSF46785 4 82 2.45E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 SUPERFAMILY SSF53850 87 291 2.71E-21 T 13-10-2018 MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011820 1232dcb969cc7000094ab1f97fc151e8 302 Gene3D G3DSA:3.40.190.10 164 266 3.0E-16 T 13-10-2018 MADE_1000435 9dacd52f6ddac8f7557f2b12a5518219 178 Pfam PF11158 Protein of unknown function (DUF2938) 19 167 4.9E-47 T 13-10-2018 IPR021329 Protein of unknown function DUF2938 MADE_1006215 6789751755d89f472f06df058b74056c 485 SUPERFAMILY SSF56935 15 485 1.21E-30 T 13-10-2018 MADE_1006215 6789751755d89f472f06df058b74056c 485 Pfam PF00593 TonB dependent receptor 22 484 6.6E-20 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1009935 5131d804f93106e154356f55f3161512 199 Pfam PF06930 Protein of unknown function (DUF1282) 9 180 1.2E-38 T 13-10-2018 IPR009698 Protein of unknown function DUF1282 MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 168 195 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 SMART SM00829 12 331 2.7E-7 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 SUPERFAMILY SSF51735 139 301 5.73E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 1.8E-29 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 Pfam PF00107 Zinc-binding dehydrogenase 175 297 1.3E-23 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 SUPERFAMILY SSF50129 4 161 1.53E-46 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 Gene3D G3DSA:3.90.180.10 11 331 5.4E-122 T 13-10-2018 MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 13-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 MADE_1007575 152990673e949ee548d5c3d6c522ea23 333 Gene3D G3DSA:3.40.50.720 149 303 5.4E-122 T 13-10-2018 MADE_1006070 b96fd57aa82951704e171f0f2c1a5097 545 Gene3D G3DSA:3.30.750.24 407 534 3.5E-19 T 13-10-2018 IPR036513 STAS domain superfamily MADE_1006070 b96fd57aa82951704e171f0f2c1a5097 545 Pfam PF00916 Sulfate permease family 9 365 1.1E-81 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 MADE_1006070 b96fd57aa82951704e171f0f2c1a5097 545 SUPERFAMILY SSF52091 421 526 3.34E-13 T 13-10-2018 IPR036513 STAS domain superfamily MADE_1006070 b96fd57aa82951704e171f0f2c1a5097 545 Pfam PF01740 STAS domain 423 521 1.6E-9 T 13-10-2018 IPR002645 STAS domain MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 Pfam PF08212 Lipocalin-like domain 35 174 1.5E-46 T 13-10-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 Gene3D G3DSA:2.40.128.20 13 176 8.2E-52 T 13-10-2018 IPR012674 Calycin MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 SUPERFAMILY SSF50814 12 175 1.53E-48 T 13-10-2018 IPR012674 Calycin MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PIRSF PIRSF036893 5 179 3.4E-45 T 13-10-2018 IPR022271 Lipocalin, ApoD type MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PRINTS PR01171 Bacterial lipocalin signature 51 67 1.1E-38 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PRINTS PR01171 Bacterial lipocalin signature 104 118 1.1E-38 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PRINTS PR01171 Bacterial lipocalin signature 137 148 1.1E-38 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PRINTS PR01171 Bacterial lipocalin signature 34 48 1.1E-38 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PRINTS PR01171 Bacterial lipocalin signature 70 79 1.1E-38 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PRINTS PR01171 Bacterial lipocalin signature 121 129 1.1E-38 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 PRINTS PR01171 Bacterial lipocalin signature 164 174 1.1E-38 T 13-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 MADE_000001023385 51c2b2c862965ffe480c73dd9c0ebd2d 180 ProSitePatterns PS00213 Lipocalin signature. 33 46 - T 13-10-2018 IPR022272 Lipocalin family conserved site MADE_000001021680 737773bc6a4090106b116c2c02b013aa 388 Gene3D G3DSA:2.60.120.650 16 215 1.6E-76 T 13-10-2018 MADE_000001021680 737773bc6a4090106b116c2c02b013aa 388 SMART SM00558 84 230 3.0E-8 T 13-10-2018 IPR003347 JmjC domain MADE_000001021680 737773bc6a4090106b116c2c02b013aa 388 SUPERFAMILY SSF51197 16 290 5.08E-71 T 13-10-2018 MADE_000001021680 737773bc6a4090106b116c2c02b013aa 388 Gene3D G3DSA:1.10.10.2510 216 387 1.8E-17 T 13-10-2018 MADE_000001021680 737773bc6a4090106b116c2c02b013aa 388 Pfam PF08007 Cupin superfamily protein 21 284 1.3E-76 T 13-10-2018 IPR003347 JmjC domain MADE_1001265 c9ad1161cc5f90b9092c7dc4b9bf927d 163 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001265 c9ad1161cc5f90b9092c7dc4b9bf927d 163 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 29 4.5E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001265 c9ad1161cc5f90b9092c7dc4b9bf927d 163 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 29 9.7E-9 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001265 c9ad1161cc5f90b9092c7dc4b9bf927d 163 Gene3D G3DSA:3.30.700.10 10 161 4.4E-16 T 13-10-2018 MADE_1001265 c9ad1161cc5f90b9092c7dc4b9bf927d 163 SUPERFAMILY SSF54523 10 102 1.49E-12 T 13-10-2018 MADE_1020070 65cb748bdc967ff35aabd9c7dcde8342 403 Pfam PF02628 Cytochrome oxidase assembly protein 3 330 2.6E-86 T 13-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 MADE_1001300 86fb2e50005ffc8f2c3a79cb27fb1359 296 Gene3D G3DSA:2.40.10.350 180 257 2.6E-33 T 13-10-2018 MADE_1001300 86fb2e50005ffc8f2c3a79cb27fb1359 296 Pfam PF04085 rod shape-determining protein MreC 125 269 8.0E-35 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MADE_1001300 86fb2e50005ffc8f2c3a79cb27fb1359 296 PIRSF PIRSF038471 2 284 1.9E-79 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MADE_1001300 86fb2e50005ffc8f2c3a79cb27fb1359 296 Gene3D G3DSA:2.40.10.340 121 266 2.6E-33 T 13-10-2018 MADE_1001300 86fb2e50005ffc8f2c3a79cb27fb1359 296 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 2 279 8.1E-73 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 MADE_000001021950 14cf040592824c194d12484bc026cd8e 276 Gene3D G3DSA:3.40.50.1000 3 270 2.0E-49 T 13-10-2018 IPR023214 HAD superfamily MADE_000001021950 14cf040592824c194d12484bc026cd8e 276 SUPERFAMILY SSF56784 3 274 6.37E-52 T 13-10-2018 IPR036412 HAD-like superfamily MADE_000001021950 14cf040592824c194d12484bc026cd8e 276 Gene3D G3DSA:3.30.1240.10 82 201 2.0E-49 T 13-10-2018 MADE_000001021950 14cf040592824c194d12484bc026cd8e 276 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 270 1.7E-40 T 13-10-2018 IPR000150 Cof family GO:0016787 MADE_000001021950 14cf040592824c194d12484bc026cd8e 276 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 242 1.8E-22 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 MADE_000001021950 14cf040592824c194d12484bc026cd8e 276 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 13-10-2018 MADE_000001021950 14cf040592824c194d12484bc026cd8e 276 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 270 4.6E-43 T 13-10-2018 MADE_1018420 7a55d5d1975a17fad8c002ce8dff152f 149 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 30 138 1.7E-50 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MADE_1018420 7a55d5d1975a17fad8c002ce8dff152f 149 SUPERFAMILY SSF109635 8 108 3.79E-36 T 13-10-2018 IPR037187 DksA, N-terminal domain superfamily MADE_1018420 7a55d5d1975a17fad8c002ce8dff152f 149 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 26 148 28.842 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 MADE_1018420 7a55d5d1975a17fad8c002ce8dff152f 149 Gene3D G3DSA:1.20.120.910 19 148 2.3E-35 T 13-10-2018 MADE_1018420 7a55d5d1975a17fad8c002ce8dff152f 149 SUPERFAMILY SSF57716 109 147 1.85E-9 T 13-10-2018 MADE_1018420 7a55d5d1975a17fad8c002ce8dff152f 149 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 109 138 1.3E-9 T 13-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 MADE_1018420 7a55d5d1975a17fad8c002ce8dff152f 149 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 112 136 - T 13-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site MADE_1015410 6b5047d00c38c1363eceb00cb689b3c5 115 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 107 4.2E-9 T 13-10-2018 IPR008407 Branched-chain amino acid transport, AzlD MADE_000001022765 191368359637c46f9443df5dccc58417 366 Gene3D G3DSA:1.50.10.10 20 366 2.4E-99 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 MADE_000001022765 191368359637c46f9443df5dccc58417 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 57 70 2.1E-21 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 MADE_000001022765 191368359637c46f9443df5dccc58417 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 185 202 2.1E-21 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 MADE_000001022765 191368359637c46f9443df5dccc58417 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 117 135 2.1E-21 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 MADE_000001022765 191368359637c46f9443df5dccc58417 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 348 362 2.1E-21 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 MADE_000001022765 191368359637c46f9443df5dccc58417 366 PRINTS PR00735 Glycosyl hydrolase family 8 signature 261 270 2.1E-21 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 MADE_000001022765 191368359637c46f9443df5dccc58417 366 Pfam PF01270 Glycosyl hydrolases family 8 18 360 3.1E-68 T 13-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 MADE_000001022765 191368359637c46f9443df5dccc58417 366 SUPERFAMILY SSF48208 7 364 4.71E-83 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 MADE_1010205 7aa3b3aecc5d23167297961c958e352f 170 Pfam PF00875 DNA photolyase 18 150 6.5E-25 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 MADE_1010205 7aa3b3aecc5d23167297961c958e352f 170 SUPERFAMILY SSF52425 16 158 1.09E-33 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 MADE_1010205 7aa3b3aecc5d23167297961c958e352f 170 Gene3D G3DSA:3.40.50.620 3 155 9.2E-29 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 178 203 - T 13-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 Gene3D G3DSA:3.40.50.720 17 371 8.8E-125 T 13-10-2018 MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 16 145 5.8E-36 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 SUPERFAMILY SSF52283 2 176 1.11E-41 T 13-10-2018 MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 SMART SM01003 4 145 3.6E-46 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 150 375 1.9E-60 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 Gene3D G3DSA:3.40.50.720 145 325 8.8E-125 T 13-10-2018 MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 SUPERFAMILY SSF51735 145 318 1.71E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1019520 ee6f8931d71a808ffe4850bbc4b0a678 385 SMART SM01002 154 318 9.2E-71 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain MADE_1008240 0e2bcca270cfbddfd41adc3f98d0b32d 299 Pfam PF01609 Transposase DDE domain 111 285 4.0E-31 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1008240 0e2bcca270cfbddfd41adc3f98d0b32d 299 Pfam PF05598 Transposase domain (DUF772) 24 98 7.6E-20 T 13-10-2018 IPR008490 Transposase InsH, N-terminal MADE_1008860 0e2bcca270cfbddfd41adc3f98d0b32d 299 Pfam PF01609 Transposase DDE domain 111 285 4.0E-31 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1008860 0e2bcca270cfbddfd41adc3f98d0b32d 299 Pfam PF05598 Transposase domain (DUF772) 24 98 7.6E-20 T 13-10-2018 IPR008490 Transposase InsH, N-terminal MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.7E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.7E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.7E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.7E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 4.7E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.7E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 Pfam PF00106 short chain dehydrogenase 9 197 3.0E-46 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 Gene3D G3DSA:3.40.50.720 4 230 2.6E-60 T 13-10-2018 MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 SUPERFAMILY SSF51735 8 217 8.39E-58 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1014150 6601e8532ee2259107dcaaedc9932496 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1007730 531520b0bb909743289520d4a0347cfd 374 Pfam PF01882 Protein of unknown function DUF58 249 297 5.8E-5 T 13-10-2018 IPR002881 Domain of unknown function DUF58 MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 SUPERFAMILY SSF50891 1 161 5.55E-61 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 PIRSF PIRSF001467 1 162 6.3E-28 T 13-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 Gene3D G3DSA:2.40.100.10 1 163 9.5E-69 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 1 160 1.1E-48 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 9.0E-14 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 9.0E-14 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1010010 1188c096d557cfb2a69fcc39b89fc20a 163 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 9.0E-14 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.9E-34 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 SMART SM00411 1 90 2.5E-43 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 SUPERFAMILY SSF47729 1 90 2.06E-32 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 7.2E-21 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 7.2E-21 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 7.2E-21 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1012735 d61468c71289de98edf9f5ec7d7f0a13 90 Gene3D G3DSA:4.10.520.10 1 90 4.2E-36 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MADE_1018440 985cbc318875359a86bb60e0f542dd55 264 SUPERFAMILY SSF51621 3 263 1.08E-107 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MADE_1018440 985cbc318875359a86bb60e0f542dd55 264 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 258 3.2E-110 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MADE_1018440 985cbc318875359a86bb60e0f542dd55 264 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 263 42.993 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MADE_1018440 985cbc318875359a86bb60e0f542dd55 264 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 264 2.0E-112 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MADE_1018440 985cbc318875359a86bb60e0f542dd55 264 PIRSF PIRSF000388 1 264 7.4E-103 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 MADE_1018440 985cbc318875359a86bb60e0f542dd55 264 Gene3D G3DSA:3.20.20.60 1 264 3.2E-109 T 13-10-2018 MADE_1010930 d08ac7bed51dbf9c854bb7d3b31d91c7 407 SUPERFAMILY SSF53448 38 404 2.25E-94 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1010930 d08ac7bed51dbf9c854bb7d3b31d91c7 407 Gene3D G3DSA:3.90.550.10 14 325 1.9E-40 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1000775 d34d96f224e98c959c1c096578600ead 128 SUPERFAMILY SSF55298 1 127 3.93E-45 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MADE_1000775 d34d96f224e98c959c1c096578600ead 128 Gene3D G3DSA:3.30.1330.40 1 126 3.1E-49 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 MADE_1000775 d34d96f224e98c959c1c096578600ead 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 13-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 MADE_1000775 d34d96f224e98c959c1c096578600ead 128 Pfam PF01042 Endoribonuclease L-PSP 9 124 2.2E-41 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 MADE_1000775 d34d96f224e98c959c1c096578600ead 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 124 6.4E-51 T 13-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 MADE_1018025 391499c78ffb35d0fe898a387b31ee73 113 SUPERFAMILY SSF47413 36 91 1.49E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1018025 391499c78ffb35d0fe898a387b31ee73 113 Gene3D G3DSA:1.10.260.40 28 96 6.8E-14 T 13-10-2018 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 SMART SM00535 22 150 1.5E-54 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 Gene3D G3DSA:3.30.160.20 155 226 7.8E-17 T 13-10-2018 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 SUPERFAMILY SSF69065 7 155 3.49E-48 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 SMART SM00358 157 225 1.2E-15 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 Gene3D G3DSA:1.10.1520.10 7 153 1.0E-45 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 ProSitePatterns PS00517 Ribonuclease III family signature. 39 47 - T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 11 224 3.5E-73 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 Pfam PF14622 Ribonuclease-III-like 20 139 4.4E-33 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 Hamap MF_00104 Ribonuclease 3 [rnc]. 10 221 29.796 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 Pfam PF00035 Double-stranded RNA binding motif 157 224 6.6E-11 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain MADE_1012515 5101ce4652d67cc61de572d75d5a994a 228 SUPERFAMILY SSF54768 111 224 2.81E-24 T 13-10-2018 MADE_1012360 b956e28f95776a69413a05ba2162aae6 203 Gene3D G3DSA:1.10.1740.10 24 106 2.5E-22 T 13-10-2018 MADE_1012360 b956e28f95776a69413a05ba2162aae6 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 199 6.5E-25 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 MADE_1012360 b956e28f95776a69413a05ba2162aae6 203 Gene3D G3DSA:1.10.10.10 135 203 3.0E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1012360 b956e28f95776a69413a05ba2162aae6 203 Pfam PF04542 Sigma-70 region 2 43 109 7.8E-16 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1012360 b956e28f95776a69413a05ba2162aae6 203 SUPERFAMILY SSF88946 27 122 1.18E-20 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 MADE_1012360 b956e28f95776a69413a05ba2162aae6 203 Pfam PF08281 Sigma-70, region 4 143 195 5.0E-13 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 MADE_1012360 b956e28f95776a69413a05ba2162aae6 203 SUPERFAMILY SSF88659 139 200 1.44E-12 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like MADE_1012315 df22d1e836deb657ac9bc237f2205430 209 Pfam PF00117 Glutamine amidotransferase class-I 23 206 3.6E-22 T 13-10-2018 IPR017926 Glutamine amidotransferase MADE_1012315 df22d1e836deb657ac9bc237f2205430 209 PIRSF PIRSF000495 10 209 2.1E-65 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MADE_1012315 df22d1e836deb657ac9bc237f2205430 209 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 11 209 33.016 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MADE_1012315 df22d1e836deb657ac9bc237f2205430 209 SUPERFAMILY SSF52317 10 208 6.39E-53 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1012315 df22d1e836deb657ac9bc237f2205430 209 Gene3D G3DSA:3.40.50.880 6 209 1.9E-68 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1012315 df22d1e836deb657ac9bc237f2205430 209 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 12 208 7.8E-66 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 MADE_1000490 67e57f7d2c44b86b847afdad5db5b4fa 169 Pfam PF00196 Bacterial regulatory proteins, luxR family 102 156 2.5E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1000490 67e57f7d2c44b86b847afdad5db5b4fa 169 SMART SM00421 100 157 2.7E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1000490 67e57f7d2c44b86b847afdad5db5b4fa 169 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 103 117 5.4E-5 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1000490 67e57f7d2c44b86b847afdad5db5b4fa 169 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 133 145 5.4E-5 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1000490 67e57f7d2c44b86b847afdad5db5b4fa 169 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 117 133 5.4E-5 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_1000490 67e57f7d2c44b86b847afdad5db5b4fa 169 SUPERFAMILY SSF46894 94 158 1.94E-13 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1000490 67e57f7d2c44b86b847afdad5db5b4fa 169 Gene3D G3DSA:1.10.10.10 65 160 2.2E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016570 d563e49269b0a4f0be7d20f9105a4250 153 SUPERFAMILY SSF53613 1 138 3.52E-21 T 13-10-2018 IPR029056 Ribokinase-like MADE_1016570 d563e49269b0a4f0be7d20f9105a4250 153 Pfam PF00294 pfkB family carbohydrate kinase 20 141 4.8E-15 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB MADE_1016570 d563e49269b0a4f0be7d20f9105a4250 153 Gene3D G3DSA:3.40.1190.20 1 152 1.8E-22 T 13-10-2018 IPR029056 Ribokinase-like MADE_000001022380 f9f9bbd94a124040de3bc79e231a2152 209 Gene3D G3DSA:3.40.50.2020 1 209 3.1E-72 T 13-10-2018 MADE_000001022380 f9f9bbd94a124040de3bc79e231a2152 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 209 43.198 T 13-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MADE_000001022380 f9f9bbd94a124040de3bc79e231a2152 209 SUPERFAMILY SSF53271 3 207 2.62E-65 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like MADE_000001022380 f9f9bbd94a124040de3bc79e231a2152 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 1.8E-85 T 13-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 MADE_000001022380 f9f9bbd94a124040de3bc79e231a2152 209 Pfam PF14681 Uracil phosphoribosyltransferase 7 208 7.3E-67 T 13-10-2018 MADE_1009555 ac7c9d36ff871a4c6e46dde3b0de3d83 649 Gene3D G3DSA:3.20.20.80 34 210 3.1E-25 T 13-10-2018 MADE_1009555 ac7c9d36ff871a4c6e46dde3b0de3d83 649 Gene3D G3DSA:3.20.20.80 309 543 4.0E-38 T 13-10-2018 MADE_1009555 ac7c9d36ff871a4c6e46dde3b0de3d83 649 Pfam PF00128 Alpha amylase, catalytic domain 325 488 1.2E-12 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009555 ac7c9d36ff871a4c6e46dde3b0de3d83 649 Pfam PF00128 Alpha amylase, catalytic domain 110 205 4.2E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009555 ac7c9d36ff871a4c6e46dde3b0de3d83 649 SUPERFAMILY SSF51445 64 548 9.86E-84 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1009555 ac7c9d36ff871a4c6e46dde3b0de3d83 649 SMART SM00642 72 510 3.1E-7 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 381 38.026 T 13-10-2018 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00750+1.1.1.290 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 288 6.1E-15 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 Gene3D G3DSA:3.40.50.720 1 285 5.1E-96 T 13-10-2018 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 SUPERFAMILY SSF52283 4 102 7.44E-17 T 13-10-2018 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 Gene3D G3DSA:3.40.50.720 93 265 5.1E-96 T 13-10-2018 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 SUPERFAMILY SSF51735 92 265 3.79E-30 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 264 5.5E-29 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 Gene3D G3DSA:3.30.1370.170 309 400 3.4E-10 T 13-10-2018 IPR038251 PdxB, dimerisation domain superfamily KEGG: 00750+1.1.1.290 MADE_1011920 24dc5622c2313b9d9d04d98cbb8d0640 402 Pfam PF11890 Domain of unknown function (DUF3410) 319 396 2.0E-9 T 13-10-2018 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00750+1.1.1.290 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 425 437 - T 13-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 SMART SM00219 291 560 6.2E-4 T 13-10-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 SMART SM00332 9 250 4.5E-5 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 Pfam PF00069 Protein kinase domain 327 554 8.9E-33 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 Pfam PF13672 Protein phosphatase 2C 24 207 7.1E-17 T 13-10-2018 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 Gene3D G3DSA:1.10.510.10 291 573 2.3E-43 T 13-10-2018 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 SUPERFAMILY SSF56112 288 561 1.62E-48 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 Gene3D G3DSA:3.60.40.10 5 253 9.0E-32 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1007715 cd370eb07742b78cc1c160fd7dc87f1b 605 SUPERFAMILY SSF81606 18 251 2.62E-30 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 MADE_1015970 299a3f95306e86dd0d727a79864b2941 125 Pfam PF00072 Response regulator receiver domain 4 116 4.2E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015970 299a3f95306e86dd0d727a79864b2941 125 SMART SM00448 2 117 5.3E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015970 299a3f95306e86dd0d727a79864b2941 125 Gene3D G3DSA:3.40.50.2300 3 125 4.9E-21 T 13-10-2018 MADE_1015970 299a3f95306e86dd0d727a79864b2941 125 SUPERFAMILY SSF52172 3 121 3.27E-23 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1002990 58eca76b8c2f211c5b70d1f1cd591ff9 234 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 188 4.2E-33 T 13-10-2018 IPR003740 Uncharacterised membrane protein YitT MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 Gene3D G3DSA:2.40.50.140 3 77 3.2E-30 T 13-10-2018 MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 Gene3D G3DSA:1.20.1440.120 80 234 2.1E-39 T 13-10-2018 MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 Pfam PF11967 Recombination protein O N terminal 1 78 4.7E-24 T 13-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 TIGRFAM TIGR00613 reco: DNA repair protein RecO 9 149 4.9E-28 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 SUPERFAMILY SSF50249 3 76 1.44E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 Hamap MF_00201 DNA repair protein RecO [recO]. 2 232 19.026 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 Pfam PF02565 Recombination protein O C terminal 83 226 7.4E-13 T 13-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 MADE_1004025 f173d653f03a00e147ee654c47fef6b0 234 SUPERFAMILY SSF57863 86 152 8.11E-7 T 13-10-2018 IPR037278 ARFGAP/RecO-like zinc finger MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 11 458 6.7E-157 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 Pfam PF06969 HemN C-terminal domain 364 431 4.0E-7 T 13-10-2018 IPR010723 HemN, C-terminal MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 Gene3D G3DSA:1.10.10.920 365 458 9.4E-29 T 13-10-2018 MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 PIRSF PIRSF000167 1 455 9.9E-151 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 Gene3D G3DSA:3.80.30.20 5 363 4.9E-111 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 SMART SM00729 53 273 1.8E-43 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 SUPERFAMILY SSF102114 11 445 6.93E-116 T 13-10-2018 MADE_1013500 1e64ce5e20085e5cb8ddb9e6ce19c151 458 Pfam PF04055 Radical SAM superfamily 58 227 1.1E-14 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1002815 7bf1ff1e8ad7714379e48bb4dd54ac4f 99 Pfam PF02416 mttA/Hcf106 family 4 49 2.3E-7 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MADE_1002815 7bf1ff1e8ad7714379e48bb4dd54ac4f 99 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 80 2.1E-26 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 MADE_1002815 7bf1ff1e8ad7714379e48bb4dd54ac4f 99 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 9.4E-21 T 13-10-2018 MADE_1002815 7bf1ff1e8ad7714379e48bb4dd54ac4f 99 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 9.4E-21 T 13-10-2018 MADE_1002815 7bf1ff1e8ad7714379e48bb4dd54ac4f 99 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 9.4E-21 T 13-10-2018 MADE_1012050 5bde0381cbbb8b760fddf5bd9fba8865 115 SUPERFAMILY SSF69118 5 108 3.4E-29 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MADE_1012050 5bde0381cbbb8b760fddf5bd9fba8865 115 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 85 3.1E-13 T 13-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MADE_1012050 5bde0381cbbb8b760fddf5bd9fba8865 115 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 3.3E-22 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MADE_1012050 5bde0381cbbb8b760fddf5bd9fba8865 115 Gene3D G3DSA:1.20.1290.10 1 115 1.5E-36 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 Gene3D G3DSA:3.20.20.450 137 390 9.2E-71 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 SMART SM00052 144 383 1.6E-38 T 13-10-2018 IPR001633 EAL domain MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 SUPERFAMILY SSF141868 154 378 1.31E-56 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 Pfam PF00563 EAL domain 153 378 1.8E-51 T 13-10-2018 IPR001633 EAL domain MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 Gene3D G3DSA:3.30.70.3200 1 136 2.3E-35 T 13-10-2018 MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 SUPERFAMILY SSF54975 2 123 7.52E-31 T 13-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 SMART SM01034 2 94 1.1E-32 T 13-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 MADE_1000865 0eaaaa09eff289c91750a009345836b2 390 Pfam PF04940 Sensors of blue-light using FAD 2 91 1.4E-27 T 13-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 MADE_000001022820 8e5b41e9d6aaedbf07add126c73f6f62 546 Pfam PF07969 Amidohydrolase family 65 544 9.3E-103 T 13-10-2018 IPR013108 Amidohydrolase 3 MADE_000001022820 8e5b41e9d6aaedbf07add126c73f6f62 546 Gene3D G3DSA:2.30.40.10 41 521 2.9E-143 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_000001022820 8e5b41e9d6aaedbf07add126c73f6f62 546 Gene3D G3DSA:3.20.20.140 77 503 2.9E-143 T 13-10-2018 MADE_000001022820 8e5b41e9d6aaedbf07add126c73f6f62 546 SUPERFAMILY SSF51338 22 544 2.53E-13 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_000001022820 8e5b41e9d6aaedbf07add126c73f6f62 546 SUPERFAMILY SSF51556 76 504 1.88E-38 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_000001022820 8e5b41e9d6aaedbf07add126c73f6f62 546 Gene3D G3DSA:3.10.310.70 95 212 2.9E-143 T 13-10-2018 MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 Pfam PF08668 HDOD domain 204 320 2.3E-14 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 SUPERFAMILY SSF109604 181 400 2.39E-42 T 13-10-2018 MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 SMART SM00052 5 195 1.1E-4 T 13-10-2018 IPR001633 EAL domain MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 Gene3D G3DSA:3.20.20.450 3 193 6.9E-19 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 PIRSF PIRSF003180 1 404 3.8E-134 T 13-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 Pfam PF00563 EAL domain 77 190 1.2E-14 T 13-10-2018 IPR001633 EAL domain MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 Gene3D G3DSA:1.10.3210.10 194 338 1.9E-23 T 13-10-2018 MADE_1018365 0cd5034a20529bd0afafbb2e30eafc07 408 SUPERFAMILY SSF141868 4 192 4.97E-30 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000820 397fc1e4efe76c34d4936c2b1dccaac9 276 Gene3D G3DSA:3.30.70.100 174 266 1.5E-24 T 13-10-2018 MADE_1000820 397fc1e4efe76c34d4936c2b1dccaac9 276 Pfam PF00924 Mechanosensitive ion channel 66 262 1.1E-51 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1000820 397fc1e4efe76c34d4936c2b1dccaac9 276 SUPERFAMILY SSF50182 108 173 7.52E-18 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1000820 397fc1e4efe76c34d4936c2b1dccaac9 276 Gene3D G3DSA:2.30.30.60 123 172 6.6E-20 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily MADE_1000820 397fc1e4efe76c34d4936c2b1dccaac9 276 SUPERFAMILY SSF82689 175 273 4.58E-30 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 MADE_1000820 397fc1e4efe76c34d4936c2b1dccaac9 276 SUPERFAMILY SSF82861 21 106 3.4E-17 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 SMART SM00919 269 529 7.4E-124 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 Hamap MF_01619 NAD-dependent malic enzyme [maeA]. 2 563 68.686 T 13-10-2018 IPR023667 NAD-dependent malic enzyme, proteobacteria GO:0004471|GO:0055114 KEGG: 00620+1.1.1.38|MetaCyc: PWY-6339 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 Pfam PF03949 Malic enzyme, NAD binding domain 269 528 1.5E-99 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 SUPERFAMILY SSF51735 269 560 6.9E-94 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PRINTS PR00072 Malic enzyme signature 265 281 3.4E-73 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PRINTS PR00072 Malic enzyme signature 296 312 3.4E-73 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PRINTS PR00072 Malic enzyme signature 406 422 3.4E-73 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PRINTS PR00072 Malic enzyme signature 85 109 3.4E-73 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PRINTS PR00072 Malic enzyme signature 145 174 3.4E-73 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PRINTS PR00072 Malic enzyme signature 181 203 3.4E-73 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PRINTS PR00072 Malic enzyme signature 240 258 3.4E-73 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 SUPERFAMILY SSF53223 5 268 1.44E-109 T 13-10-2018 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 PIRSF PIRSF000106 1 561 1.3E-226 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 Gene3D G3DSA:3.40.50.720 267 562 1.5E-105 T 13-10-2018 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 ProSitePatterns PS00331 Malic enzymes signature. 265 281 - T 13-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 Pfam PF00390 Malic enzyme, N-terminal domain 79 259 9.2E-78 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 Gene3D G3DSA:3.40.50.10380 13 266 1.7E-114 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 MADE_1002600 cec8d4c5fae716c9c3b1199ddba28c34 563 SMART SM01274 79 259 1.7E-105 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 MADE_1011700 7a22b90f80442a82d7c09b571d599dbd 230 SUPERFAMILY SSF100950 6 227 1.26E-53 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1011700 7a22b90f80442a82d7c09b571d599dbd 230 Gene3D G3DSA:3.40.50.1360 2 230 1.4E-68 T 13-10-2018 MADE_1011700 7a22b90f80442a82d7c09b571d599dbd 230 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 9 224 2.1E-55 T 13-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 MADE_1011700 7a22b90f80442a82d7c09b571d599dbd 230 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 227 8.2E-57 T 13-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 MADE_1003370 a77f75c3d47a0c33890f045c82c66790 211 Gene3D G3DSA:3.40.50.150 2 210 1.6E-72 T 13-10-2018 MADE_1003370 a77f75c3d47a0c33890f045c82c66790 211 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 8 208 1.9E-67 T 13-10-2018 MADE_1003370 a77f75c3d47a0c33890f045c82c66790 211 SUPERFAMILY SSF53335 11 206 4.97E-41 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1003370 a77f75c3d47a0c33890f045c82c66790 211 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 133 148 - T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MADE_1003370 a77f75c3d47a0c33890f045c82c66790 211 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 2 211 36.425 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MADE_1003370 a77f75c3d47a0c33890f045c82c66790 211 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 5 210 1.9E-75 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 MADE_1013265 50d95eab097c08900908ffcc9387c940 315 SUPERFAMILY SSF101898 37 288 2.88E-5 T 13-10-2018 MADE_1016460 501d2bde931548df9eb5c02c5c56848c 203 Pfam PF01081 KDPG and KHG aldolase 4 198 3.5E-60 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MADE_1016460 501d2bde931548df9eb5c02c5c56848c 203 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 13-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MADE_1016460 501d2bde931548df9eb5c02c5c56848c 203 Gene3D G3DSA:3.20.20.70 1 203 5.1E-62 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1016460 501d2bde931548df9eb5c02c5c56848c 203 SUPERFAMILY SSF51569 3 200 9.52E-58 T 13-10-2018 MADE_1016460 501d2bde931548df9eb5c02c5c56848c 203 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 5 200 3.0E-64 T 13-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 SUPERFAMILY SSF56655 1 257 6.54E-84 T 13-10-2018 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 1.2E-23 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 1.2E-23 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 1.2E-23 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 1.2E-23 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 Gene3D G3DSA:3.40.190.80 141 258 3.7E-36 T 13-10-2018 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 Pfam PF00459 Inositol monophosphatase family 2 252 3.8E-71 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 Gene3D G3DSA:3.30.540.10 1 140 2.4E-51 T 13-10-2018 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 4.6E-60 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 4.6E-60 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 4.6E-60 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 4.6E-60 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 4.6E-60 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 4.6E-60 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site MADE_1012935 71b33ed85cae690266df25cb3d6fbfab 258 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 SUPERFAMILY SSF52540 354 605 2.09E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 ProSitePatterns PS00211 ABC transporters family signature. 507 521 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 Pfam PF00005 ABC transporter 382 535 1.1E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 SUPERFAMILY SSF90123 30 342 3.4E-53 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 Gene3D G3DSA:1.20.1560.10 8 342 2.2E-28 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 Pfam PF00664 ABC transporter transmembrane region 44 308 6.1E-22 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 Gene3D G3DSA:3.40.50.300 351 608 1.3E-90 T 13-10-2018 MADE_000001023355 be4737e947ec9b77a38d8e4fe99e462c 613 SMART SM00382 390 581 1.1E-19 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001023360 616071465e7b4e1678b4c356b9447ea4 207 Pfam PF03737 Aldolase/RraA 14 160 3.0E-38 T 13-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MADE_000001023360 616071465e7b4e1678b4c356b9447ea4 207 Gene3D G3DSA:3.50.30.100 5 183 1.2E-47 T 13-10-2018 MADE_000001023360 616071465e7b4e1678b4c356b9447ea4 207 SUPERFAMILY SSF89562 11 166 6.28E-40 T 13-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MADE_1012540 05af3386ad4239883ac6f7604f47fede 193 SUPERFAMILY SSF89069 4 68 9.68E-19 T 13-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 MADE_1012540 05af3386ad4239883ac6f7604f47fede 193 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 4 83 1.2E-25 T 13-10-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 MADE_1012540 05af3386ad4239883ac6f7604f47fede 193 Gene3D G3DSA:1.10.10.880 3 68 6.1E-22 T 13-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 MADE_1012540 05af3386ad4239883ac6f7604f47fede 193 PIRSF PIRSF016938 1 180 9.9E-22 T 13-10-2018 IPR026279 Sigma-E factor negative regulatory protein RseA GO:0016989 MADE_1012540 05af3386ad4239883ac6f7604f47fede 193 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 125 174 1.1E-5 T 13-10-2018 IPR005573 Anti sigma-E protein RseA, C-terminal MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 Pfam PF00162 Phosphoglycerate kinase 6 378 1.7E-146 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PIRSF PIRSF000724 1 391 3.8E-141 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 341 352 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 308 333 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 364 381 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 5.9E-82 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 Gene3D G3DSA:3.40.50.1260 8 386 9.8E-156 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 388 39.916 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 Gene3D G3DSA:3.40.50.1260 165 378 9.8E-156 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 13-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004355 930e2c1bce4bbc59b980b404db4d06b3 391 SUPERFAMILY SSF53748 4 388 2.0E-149 T 13-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1013005 5409a20e119901ca3335919bd3c4fa82 222 Pfam PF06693 Protein of unknown function (DUF1190) 58 212 7.4E-48 T 13-10-2018 IPR009576 Biofilm formation YgiB MADE_1007400 e702295782f1bc9ff4d24f8447cc69e8 186 Gene3D G3DSA:2.40.160.20 29 186 7.3E-18 T 13-10-2018 MADE_1007400 e702295782f1bc9ff4d24f8447cc69e8 186 Pfam PF13505 Outer membrane protein beta-barrel domain 17 186 1.1E-9 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel MADE_1007400 e702295782f1bc9ff4d24f8447cc69e8 186 SUPERFAMILY SSF56925 34 186 1.94E-15 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Gene3D G3DSA:3.40.50.12740 727 846 1.6E-38 T 13-10-2018 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 689 702 2.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 665 683 2.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 648 658 2.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 644 2.3E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SUPERFAMILY SSF55874 531 701 4.32E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SMART SM00387 589 705 3.5E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SUPERFAMILY SSF52172 727 844 1.85E-35 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SUPERFAMILY SSF47384 465 543 2.55E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Pfam PF13424 Tetratricopeptide repeat 230 294 1.7E-8 T 13-10-2018 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SUPERFAMILY SSF48452 193 390 1.73E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SMART SM00448 728 840 1.6E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Pfam PF00072 Response regulator receiver domain 730 840 7.5E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SMART SM00388 477 542 1.2E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Pfam PF00512 His Kinase A (phospho-acceptor) domain 478 542 4.5E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 590 701 1.0E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SMART SM00028 266 299 140.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SMART SM00028 304 337 20.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 SMART SM00028 226 259 0.0019 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Gene3D G3DSA:3.30.565.10 543 708 5.9E-46 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Gene3D G3DSA:1.10.287.130 484 542 2.1E-17 T 13-10-2018 MADE_000001021260 77724b21639e41d8ca943234290ff3d9 847 Gene3D G3DSA:1.25.40.10 189 483 1.2E-23 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1003805 31c1cdf1427bf8eff0df92a9e84e4580 164 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 8 131 3.4E-23 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1003805 31c1cdf1427bf8eff0df92a9e84e4580 164 Gene3D G3DSA:3.30.70.560 4 157 1.3E-34 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1003805 31c1cdf1427bf8eff0df92a9e84e4580 164 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 6 131 2.8E-23 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1003805 31c1cdf1427bf8eff0df92a9e84e4580 164 SUPERFAMILY SSF55083 4 157 4.58E-40 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 132 242 3.6E-22 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 297 454 3.0E-46 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 290 297 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 SMART SM00846 131 292 9.0E-55 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 286 304 1.0E-17 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 313 329 1.0E-17 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 250 263 1.0E-17 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 369 386 1.0E-17 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 Gene3D G3DSA:3.40.50.720 133 467 1.4E-114 T 13-10-2018 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 SUPERFAMILY SSF55347 292 455 1.19E-51 T 13-10-2018 MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 SUPERFAMILY SSF51735 132 308 1.46E-45 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1011640 ce5a8701115328ce1d61d9902131af7f 481 Gene3D G3DSA:3.30.360.10 291 456 1.4E-114 T 13-10-2018 MADE_1005550 f8dc57da9f4d05f72fce8aed9f4e428e 115 Pfam PF02411 MerT mercuric transport protein 1 114 3.1E-51 T 13-10-2018 IPR003457 Mercuric transport protein MerT GO:0015097|GO:0015694|GO:0016020 MADE_000001022805 f69d28d67260ddeacf382f9ad1ed6377 124 Pfam PF08000 Bacterial PH domain 3 120 2.0E-43 T 13-10-2018 IPR012544 Bacterial Pleckstrin homology domain MADE_000001022805 f69d28d67260ddeacf382f9ad1ed6377 124 Gene3D G3DSA:2.30.29.50 1 123 7.0E-46 T 13-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily MADE_000001022805 f69d28d67260ddeacf382f9ad1ed6377 124 SUPERFAMILY SSF50729 7 117 7.99E-38 T 13-10-2018 MADE_000001023435 2a4dd4aa3edc5353b12ce758412cab6d 297 SUPERFAMILY SSF56317 5 294 2.22E-85 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_000001023435 2a4dd4aa3edc5353b12ce758412cab6d 297 Pfam PF00795 Carbon-nitrogen hydrolase 7 275 3.4E-59 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MADE_000001023435 2a4dd4aa3edc5353b12ce758412cab6d 297 Gene3D G3DSA:3.60.110.10 1 296 2.5E-94 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 8.9E-30 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 8.9E-30 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 8.9E-30 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 8.9E-30 T 13-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 Gene3D G3DSA:3.40.640.10 60 300 1.8E-149 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 Pfam PF00155 Aminotransferase class I and II 27 392 5.3E-71 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 Gene3D G3DSA:3.90.1150.10 6 392 1.8E-149 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 SUPERFAMILY SSF53383 3 393 7.66E-103 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1013705 b3dfdcdab04b434b32046d9de19a35dc 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MADE_000001020750 59d05b6ae7b28e08af59c6427b1de4fb 258 SMART SM00287 87 153 2.0E-10 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type MADE_000001020750 59d05b6ae7b28e08af59c6427b1de4fb 258 Gene3D G3DSA:2.30.30.40 98 150 9.5E-9 T 13-10-2018 MADE_000001020750 59d05b6ae7b28e08af59c6427b1de4fb 258 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 91 257 1.2E-48 T 13-10-2018 IPR016476 SH3 domain protein MADE_000001020750 59d05b6ae7b28e08af59c6427b1de4fb 258 Pfam PF08239 Bacterial SH3 domain 99 150 4.6E-10 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Gene3D G3DSA:2.40.110.10 160 286 1.2E-27 T 13-10-2018 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 157 6.2E-13 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 SUPERFAMILY SSF56645 39 278 1.1E-56 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 592 7.4E-35 T 13-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 447 7.7E-17 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 270 2.8E-15 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 SUPERFAMILY SSF47203 286 474 1.93E-47 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Gene3D G3DSA:1.10.540.10 11 159 2.5E-17 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Gene3D G3DSA:1.20.140.10 287 460 9.8E-42 T 13-10-2018 MADE_1008790 c16554bfc2d0038971a5ec376fb46f5a 599 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 4 34 2.8E-6 T 13-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria MADE_1006550 008e0133767d8bfe0d5e3909ba0a2ce9 640 SUPERFAMILY SSF52540 75 364 2.63E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006550 008e0133767d8bfe0d5e3909ba0a2ce9 640 Pfam PF08298 PrkA AAA domain 20 376 1.2E-174 T 13-10-2018 IPR013153 PrkA AAA domain MADE_1006550 008e0133767d8bfe0d5e3909ba0a2ce9 640 SMART SM00763 19 376 2.1E-214 T 13-10-2018 IPR013153 PrkA AAA domain MADE_1006550 008e0133767d8bfe0d5e3909ba0a2ce9 640 PIRSF PIRSF000549 1 640 1.5E-291 T 13-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 MADE_1006550 008e0133767d8bfe0d5e3909ba0a2ce9 640 Pfam PF06798 PrkA serine protein kinase C-terminal domain 379 632 8.7E-75 T 13-10-2018 IPR010650 PrkA C-terminal domain MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 201 293 3.3E-11 T 13-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 Gene3D G3DSA:3.40.50.1820 386 679 1.2E-62 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 SUPERFAMILY SSF82171 41 410 9.16E-52 T 13-10-2018 MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 SUPERFAMILY SSF53474 426 678 1.43E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 Gene3D G3DSA:2.120.10.30 159 371 1.2E-29 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 Gene3D G3DSA:2.120.10.30 15 158 1.8E-23 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 Pfam PF07676 WD40-like Beta Propeller Repeat 141 154 9.7E-4 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 Pfam PF07676 WD40-like Beta Propeller Repeat 86 121 9.6E-10 T 13-10-2018 IPR011659 WD40-like Beta Propeller MADE_1004370 55e4062324a51e94dd4e93e722d1534d 685 Pfam PF00326 Prolyl oligopeptidase family 472 678 8.1E-46 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MADE_1011350 451aac175d30e24c19858d6e2a8f1e72 205 Pfam PF03458 UPF0126 domain 93 164 1.0E-18 T 13-10-2018 IPR005115 Uncharacterised domain UPF0126 MADE_1011350 451aac175d30e24c19858d6e2a8f1e72 205 Pfam PF03458 UPF0126 domain 7 79 1.6E-19 T 13-10-2018 IPR005115 Uncharacterised domain UPF0126 MADE_1015510 4c5e7e19e4dc87ff5b6745b2f34870a9 155 Gene3D G3DSA:3.40.50.2300 1 137 6.9E-40 T 13-10-2018 MADE_1015510 4c5e7e19e4dc87ff5b6745b2f34870a9 155 SUPERFAMILY SSF52788 1 134 3.66E-38 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily MADE_1015510 4c5e7e19e4dc87ff5b6745b2f34870a9 155 SMART SM00226 1 135 1.4E-37 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MADE_1015510 4c5e7e19e4dc87ff5b6745b2f34870a9 155 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 132 4.4E-21 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 SUPERFAMILY SSF51215 24 160 8.5E-9 T 13-10-2018 IPR037923 Transcription regulator HTH-like MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 SMART SM00342 197 280 1.2E-27 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 Gene3D G3DSA:1.10.10.60 177 284 1.1E-22 T 13-10-2018 MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 Gene3D G3DSA:2.60.120.280 38 158 6.8E-6 T 13-10-2018 MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 Pfam PF12833 Helix-turn-helix domain 203 280 6.3E-19 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 Pfam PF02311 AraC-like ligand binding domain 49 153 2.4E-5 T 13-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 234 276 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 MADE_1001345 3a5030c73f79dd696af57d8685e51151 284 SUPERFAMILY SSF46689 233 281 1.66E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1005420 1d2ba1bd7f34d46a97ef6f9527155042 223 SUPERFAMILY SSF53927 42 208 7.19E-54 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 MADE_1005420 1d2ba1bd7f34d46a97ef6f9527155042 223 Pfam PF14437 MafB19-like deaminase 58 204 5.7E-34 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MADE_1005420 1d2ba1bd7f34d46a97ef6f9527155042 223 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 108 145 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 MADE_1005420 1d2ba1bd7f34d46a97ef6f9527155042 223 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 63 204 43.798 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 MADE_1005420 1d2ba1bd7f34d46a97ef6f9527155042 223 Gene3D G3DSA:3.40.140.10 51 218 4.7E-60 T 13-10-2018 MADE_1000725 ae83a49ea3dc492366ffeca3f6514191 391 Pfam PF07219 HemY protein N-terminus 29 132 5.6E-22 T 13-10-2018 IPR010817 HemY, N-terminal MADE_1000725 ae83a49ea3dc492366ffeca3f6514191 391 Gene3D G3DSA:1.25.40.10 153 390 2.9E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1000725 ae83a49ea3dc492366ffeca3f6514191 391 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 7 385 1.1E-68 T 13-10-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 MADE_1000725 ae83a49ea3dc492366ffeca3f6514191 391 SUPERFAMILY SSF48452 91 208 1.11E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 Gene3D G3DSA:3.40.50.300 528 695 4.5E-10 T 13-10-2018 MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 Pfam PF04851 Type III restriction enzyme, res subunit 291 467 4.8E-7 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 Gene3D G3DSA:1.10.3210.30 5 281 2.9E-47 T 13-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 SMART SM00490 590 677 0.0039 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 SMART SM00487 282 518 5.2E-5 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 SUPERFAMILY SSF52540 302 683 1.14E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 305 681 6.0E-66 T 13-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core MADE_1014415 aa2c50e8bacc81df1e77b1a13ef235fc 915 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 29 232 7.4E-23 T 13-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain MADE_1016715 264fb94c8c53ec7d223b2344cd71920e 195 Gene3D G3DSA:3.40.470.10 4 195 5.4E-61 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1016715 264fb94c8c53ec7d223b2344cd71920e 195 SUPERFAMILY SSF52141 8 193 2.88E-49 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1016715 264fb94c8c53ec7d223b2344cd71920e 195 SMART SM00986 31 186 4.9E-26 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1016715 264fb94c8c53ec7d223b2344cd71920e 195 Pfam PF03167 Uracil DNA glycosylase superfamily 39 182 8.4E-26 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1016715 264fb94c8c53ec7d223b2344cd71920e 195 SMART SM00987 31 186 4.9E-26 T 13-10-2018 MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 273 1.4E-144 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 7.3E-24 T 13-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 SUPERFAMILY SSF51161 2 256 4.3E-75 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 0.0015 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 Gene3D G3DSA:2.160.10.10 87 257 7.0E-55 T 13-10-2018 MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 3.5E-13 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 Gene3D G3DSA:1.10.166.10 1 70 6.9E-28 T 13-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 MADE_1004950 0edbb34f3e0b0e3c747547152a99590e 274 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 56.392 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 MADE_1013900 a182b671125bd788be5f018d826c8cdb 437 Pfam PF00535 Glycosyl transferase family 2 191 283 1.5E-11 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1013900 a182b671125bd788be5f018d826c8cdb 437 SUPERFAMILY SSF53448 188 368 1.13E-24 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013900 a182b671125bd788be5f018d826c8cdb 437 Gene3D G3DSA:3.90.550.10 175 378 1.3E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_000001022450 de22dff5e56390bccbe1894ee6e5915b 240 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 26 238 8.6E-21 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 MADE_000001022450 de22dff5e56390bccbe1894ee6e5915b 240 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 238 8.2E-55 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 MADE_1016645 90bb4ae876f284dab0da06ce42885efe 121 Pfam PF00072 Response regulator receiver domain 5 112 1.8E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016645 90bb4ae876f284dab0da06ce42885efe 121 SMART SM00448 3 115 1.2E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016645 90bb4ae876f284dab0da06ce42885efe 121 SUPERFAMILY SSF52172 3 117 2.56E-28 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1016645 90bb4ae876f284dab0da06ce42885efe 121 Gene3D G3DSA:3.40.50.2300 1 118 1.0E-27 T 13-10-2018 MADE_1015425 859ce4b61877da3a3851c1fe13acc489 419 Gene3D G3DSA:1.20.1250.20 31 410 6.7E-42 T 13-10-2018 MADE_1015425 859ce4b61877da3a3851c1fe13acc489 419 Pfam PF07690 Major Facilitator Superfamily 38 369 1.3E-34 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1015425 859ce4b61877da3a3851c1fe13acc489 419 SUPERFAMILY SSF103473 31 404 6.28E-52 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 Pfam PF00875 DNA photolyase 6 158 2.1E-44 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 Gene3D G3DSA:1.25.40.80 129 282 6.4E-87 T 13-10-2018 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 Gene3D G3DSA:3.40.50.620 7 201 6.4E-87 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 SUPERFAMILY SSF52425 5 171 5.49E-55 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 Pfam PF03441 FAD binding domain of DNA photolyase 271 470 1.8E-88 T 13-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 PRINTS PR00147 DNA photolyase signature 138 154 1.1E-21 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 PRINTS PR00147 DNA photolyase signature 320 336 1.1E-21 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 PRINTS PR00147 DNA photolyase signature 340 358 1.1E-21 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 PRINTS PR00147 DNA photolyase signature 379 393 1.1E-21 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 320 332 - T 13-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 SUPERFAMILY SSF48173 190 473 9.68E-116 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 MADE_1010210 e28be3d3eb6d836d0f5ac864d66ad5c0 474 Gene3D G3DSA:1.10.579.10 289 474 1.1E-84 T 13-10-2018 MADE_1013200 2d2fddd95e91b8ee23c7f6b151771e42 483 Pfam PF13440 Polysaccharide biosynthesis protein 27 319 5.2E-60 T 13-10-2018 MADE_1008715 fb17b8a955fecd7fbce4a5b9c8624583 282 Gene3D G3DSA:3.20.10.10 127 267 4.6E-43 T 13-10-2018 MADE_1008715 fb17b8a955fecd7fbce4a5b9c8624583 282 Pfam PF01063 Amino-transferase class IV 22 253 3.7E-42 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MADE_1008715 fb17b8a955fecd7fbce4a5b9c8624583 282 Gene3D G3DSA:3.30.470.10 5 117 4.1E-21 T 13-10-2018 MADE_1008715 fb17b8a955fecd7fbce4a5b9c8624583 282 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 8 255 3.8E-75 T 13-10-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 MADE_1008715 fb17b8a955fecd7fbce4a5b9c8624583 282 SUPERFAMILY SSF56752 9 262 9.55E-55 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MADE_1012125 845792b9e45e5e3542e31e85543602ed 479 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 264 1.5E-29 T 13-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MADE_1012125 845792b9e45e5e3542e31e85543602ed 479 Pfam PF06974 Protein of unknown function (DUF1298) 305 450 1.5E-22 T 13-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 MADE_1020185 0a6232ef93758176ed39faf0463499f6 300 SUPERFAMILY SSF103481 192 285 1.31E-6 T 13-10-2018 MADE_1020185 0a6232ef93758176ed39faf0463499f6 300 SUPERFAMILY SSF103481 36 138 4.71E-10 T 13-10-2018 MADE_1020185 0a6232ef93758176ed39faf0463499f6 300 Pfam PF00892 EamA-like transporter family 151 283 8.4E-15 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1020185 0a6232ef93758176ed39faf0463499f6 300 Pfam PF00892 EamA-like transporter family 6 135 1.4E-10 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1019265 751319c505affd0edd3d7f84ae7ad9b2 246 Pfam PF02613 Nitrate reductase delta subunit 41 158 7.4E-11 T 13-10-2018 IPR020945 DMSO/Nitrate reductase chaperone MADE_1019265 751319c505affd0edd3d7f84ae7ad9b2 246 SUPERFAMILY SSF89155 2 164 8.63E-31 T 13-10-2018 IPR036411 TorD-like superfamily MADE_1019265 751319c505affd0edd3d7f84ae7ad9b2 246 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 8 161 3.3E-32 T 13-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 MADE_1019265 751319c505affd0edd3d7f84ae7ad9b2 246 Gene3D G3DSA:1.10.4070.10 69 150 2.9E-12 T 13-10-2018 MADE_1019265 751319c505affd0edd3d7f84ae7ad9b2 246 Gene3D G3DSA:1.20.120.700 4 160 2.9E-12 T 13-10-2018 MADE_1000055 443ee7defc1fa68aed11495b93b5b6e4 167 Hamap MF_01058 Der GTPase-activating protein YihI [yihI]. 1 160 14.655 T 13-10-2018 IPR007336 Der GTPase activator GO:0005096 MADE_1000055 443ee7defc1fa68aed11495b93b5b6e4 167 Pfam PF04220 Der GTPase activator (YihI) 24 152 1.4E-36 T 13-10-2018 IPR007336 Der GTPase activator GO:0005096 MADE_1010105 63f725f0f82e2939bb7b31a3c03e9866 174 SUPERFAMILY SSF51161 5 167 7.07E-47 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1010105 63f725f0f82e2939bb7b31a3c03e9866 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 4.3E-9 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1010105 63f725f0f82e2939bb7b31a3c03e9866 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 44 1.5E-4 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1010105 63f725f0f82e2939bb7b31a3c03e9866 174 Gene3D G3DSA:2.160.10.10 2 171 2.1E-61 T 13-10-2018 MADE_000001023110 205e1f5214c6284876643059d1288b31 301 SUPERFAMILY SSF56059 98 288 1.94E-48 T 13-10-2018 MADE_000001023110 205e1f5214c6284876643059d1288b31 301 Gene3D G3DSA:3.40.50.20 1 114 3.5E-39 T 13-10-2018 MADE_000001023110 205e1f5214c6284876643059d1288b31 301 Pfam PF08443 RimK-like ATP-grasp domain 98 286 8.8E-67 T 13-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 MADE_000001023110 205e1f5214c6284876643059d1288b31 301 Gene3D G3DSA:3.30.1490.20 115 181 3.0E-27 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_000001023110 205e1f5214c6284876643059d1288b31 301 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 51.976 T 13-10-2018 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK MADE_000001023110 205e1f5214c6284876643059d1288b31 301 Gene3D G3DSA:3.30.470.80 182 299 1.0E-42 T 13-10-2018 MADE_000001023110 205e1f5214c6284876643059d1288b31 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 286 1.5E-83 T 13-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 13-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.08 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 SUPERFAMILY SSF54821 108 206 6.15E-40 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 SMART SM00322 60 125 4.6E-7 T 13-10-2018 IPR004087 K Homology domain GO:0003676 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 2.5E-41 T 13-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 SUPERFAMILY SSF54814 2 106 1.36E-37 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 Pfam PF07650 KH domain 39 111 3.0E-18 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 Gene3D G3DSA:3.30.300.20 17 107 2.1E-29 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 6.5E-98 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 MADE_1002290 b2abeaa7da94ae36fded5997e23d7ff9 234 Gene3D G3DSA:3.30.1140.32 108 208 5.8E-45 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 384 409 - T 13-10-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Gene3D G3DSA:2.60.40.10 220 332 7.6E-26 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 SUPERFAMILY SSF49303 221 332 3.74E-24 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Gene3D G3DSA:2.70.98.10 743 1040 2.1E-85 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 SUPERFAMILY SSF74650 747 1038 7.06E-86 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Gene3D G3DSA:3.20.20.80 333 623 1.2E-124 T 13-10-2018 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Hamap MF_01687 Beta-galactosidase [lacZ]. 2 1040 16.847 T 13-10-2018 IPR023933 Glycoside hydrolase, family 2, beta-galactosidase GO:0016798 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Pfam PF00703 Glycosyl hydrolases family 2 220 332 1.3E-18 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 50 218 2.6E-54 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 446 460 - T 13-10-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 334 626 2.3E-113 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Pfam PF16353 Domain of unknown function(DUF4981) 639 725 4.9E-17 T 13-10-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 SUPERFAMILY SSF49785 11 218 6.24E-62 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Gene3D G3DSA:2.60.120.260 5 219 7.1E-79 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 PRINTS PR00132 Glycosyl hydrolase family 2 signature 446 461 2.2E-37 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 PRINTS PR00132 Glycosyl hydrolase family 2 signature 146 161 2.2E-37 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 PRINTS PR00132 Glycosyl hydrolase family 2 signature 530 545 2.2E-37 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 PRINTS PR00132 Glycosyl hydrolase family 2 signature 343 357 2.2E-37 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 PRINTS PR00132 Glycosyl hydrolase family 2 signature 374 392 2.2E-37 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Pfam PF02929 Beta galactosidase small chain 764 1037 2.5E-60 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 SMART SM01038 759 1038 8.1E-93 T 13-10-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 SUPERFAMILY SSF49303 620 727 4.7E-25 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 SUPERFAMILY SSF51445 334 622 3.25E-100 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1001350 ef72c17ed80f9e3aca27bd101962eeb3 1041 Gene3D G3DSA:2.60.40.10 624 730 2.5E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1009595 89447f60b956bdd965a452a70bc6cfec 841 SUPERFAMILY SSF56235 58 838 2.5E-148 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1009595 89447f60b956bdd965a452a70bc6cfec 841 Pfam PF01804 Penicillin amidase 64 829 1.9E-126 T 13-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 MADE_1009595 89447f60b956bdd965a452a70bc6cfec 841 Gene3D G3DSA:3.60.20.10 259 828 3.7E-178 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1009595 89447f60b956bdd965a452a70bc6cfec 841 Gene3D G3DSA:2.30.120.10 335 411 3.7E-178 T 13-10-2018 MADE_1009595 89447f60b956bdd965a452a70bc6cfec 841 Gene3D G3DSA:1.10.439.10 57 225 7.5E-51 T 13-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 MADE_1009595 89447f60b956bdd965a452a70bc6cfec 841 Gene3D G3DSA:1.10.1400.10 552 763 3.7E-178 T 13-10-2018 MADE_1003475 59fa98ef9075028b649a6bce4bcae042 448 Pfam PF13000 Acetyl-coenzyme A transporter 1 31 172 2.6E-8 T 13-10-2018 IPR024371 Acetyl-coenzyme A transporter 1-like GO:0008521|GO:0016021 Reactome: R-HSA-425397|Reactome: R-HSA-5619061 MADE_1003475 59fa98ef9075028b649a6bce4bcae042 448 Gene3D G3DSA:1.20.1250.20 250 446 1.4E-8 T 13-10-2018 MADE_1003475 59fa98ef9075028b649a6bce4bcae042 448 SUPERFAMILY SSF103473 25 445 2.22E-29 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1003475 59fa98ef9075028b649a6bce4bcae042 448 Gene3D G3DSA:1.20.1250.20 20 218 5.1E-12 T 13-10-2018 MADE_1011710 b9f94e0bdb82391bd2148d6adda20bc4 283 Pfam PF01380 SIS domain 124 252 1.2E-24 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MADE_1011710 b9f94e0bdb82391bd2148d6adda20bc4 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 7.1E-30 T 13-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MADE_1011710 b9f94e0bdb82391bd2148d6adda20bc4 283 Gene3D G3DSA:1.10.10.10 1 79 1.2E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1011710 b9f94e0bdb82391bd2148d6adda20bc4 283 SUPERFAMILY SSF53697 91 277 1.38E-40 T 13-10-2018 MADE_1011710 b9f94e0bdb82391bd2148d6adda20bc4 283 SUPERFAMILY SSF46689 1 80 1.15E-21 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1011710 b9f94e0bdb82391bd2148d6adda20bc4 283 Gene3D G3DSA:3.40.50.10490 93 274 1.7E-40 T 13-10-2018 MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 SUPERFAMILY SSF50129 4 139 1.14E-31 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 SUPERFAMILY SSF51735 111 285 2.3E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 Gene3D G3DSA:3.90.180.10 14 323 1.7E-95 T 13-10-2018 MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 324 1.1E-110 T 13-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 SMART SM00829 9 323 1.0E-27 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 Gene3D G3DSA:3.40.50.720 120 262 1.7E-95 T 13-10-2018 MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 86 3.3E-8 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1008555 88bf9d003e9329d7c4371d8f48b4071d 325 Pfam PF00107 Zinc-binding dehydrogenase 151 273 2.5E-24 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 SUPERFAMILY SSF141868 700 943 1.23E-64 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 Gene3D G3DSA:3.30.70.270 512 682 7.6E-48 T 13-10-2018 MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 Pfam PF00990 Diguanylate cyclase, GGDEF domain 523 678 7.3E-37 T 13-10-2018 IPR000160 GGDEF domain MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 SUPERFAMILY SSF55073 528 684 1.65E-42 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 519 680 8.8E-39 T 13-10-2018 IPR000160 GGDEF domain MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 Pfam PF13426 PAS domain 418 511 7.9E-9 T 13-10-2018 IPR000014 PAS domain MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 Pfam PF07696 7TMR-DISM extracellular 2 73 170 3.4E-6 T 13-10-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 SUPERFAMILY SSF55785 412 519 6.81E-15 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 SMART SM00052 694 941 4.4E-59 T 13-10-2018 IPR001633 EAL domain MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 399 515 3.3E-14 T 13-10-2018 IPR000014 PAS domain MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 Gene3D G3DSA:3.20.20.450 683 944 5.1E-74 T 13-10-2018 IPR035919 EAL domain superfamily MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 Pfam PF00563 EAL domain 701 936 6.6E-56 T 13-10-2018 IPR001633 EAL domain MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 Gene3D G3DSA:3.30.450.20 398 510 7.3E-18 T 13-10-2018 MADE_1000950 26e5aa26990521df8f4c513364e5c089 945 SMART SM00267 512 682 1.5E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_1019710 2ee66cf18c05fd75b34f9f9b6d97c568 97 Gene3D G3DSA:4.10.490.10 32 95 3.0E-17 T 13-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 MADE_1019710 2ee66cf18c05fd75b34f9f9b6d97c568 97 Pfam PF01355 High potential iron-sulfur protein 38 93 2.3E-15 T 13-10-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 MADE_1019710 2ee66cf18c05fd75b34f9f9b6d97c568 97 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 26 1.0E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal MADE_1019710 2ee66cf18c05fd75b34f9f9b6d97c568 97 SUPERFAMILY SSF57652 34 95 2.35E-19 T 13-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 MADE_1015525 62d55eaf10a90c580f93b1193fe676c7 132 Pfam PF00072 Response regulator receiver domain 5 115 8.1E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015525 62d55eaf10a90c580f93b1193fe676c7 132 SMART SM00448 3 115 9.6E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015525 62d55eaf10a90c580f93b1193fe676c7 132 Gene3D G3DSA:3.40.50.2300 3 128 2.6E-27 T 13-10-2018 MADE_1015525 62d55eaf10a90c580f93b1193fe676c7 132 SUPERFAMILY SSF52172 3 118 3.13E-29 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1006145 f8f57afc3df3c2e1d0a8185b87db4f07 331 SUPERFAMILY SSF161098 82 309 2.88E-22 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1006145 f8f57afc3df3c2e1d0a8185b87db4f07 331 Gene3D G3DSA:1.10.3720.10 82 320 8.8E-23 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1006145 f8f57afc3df3c2e1d0a8185b87db4f07 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 323 1.4E-41 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1006575 399c55e398d07652ff0533daa482f396 351 Gene3D G3DSA:3.55.50.30 273 347 2.4E-8 T 13-10-2018 MADE_1006575 399c55e398d07652ff0533daa482f396 351 Pfam PF16344 Domain of unknown function (DUF4974) 248 341 2.1E-10 T 13-10-2018 IPR032508 Protein FecR, C-terminal MADE_1006575 399c55e398d07652ff0533daa482f396 351 Gene3D G3DSA:2.60.120.1440 106 241 6.5E-27 T 13-10-2018 MADE_1006575 399c55e398d07652ff0533daa482f396 351 PIRSF PIRSF018266 5 347 5.6E-71 T 13-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component MADE_1006575 399c55e398d07652ff0533daa482f396 351 Pfam PF04773 FecR protein 124 216 3.9E-19 T 13-10-2018 IPR006860 FecR protein MADE_1019510 d8a83470609c5dba4e9c0363017ce7d4 462 SUPERFAMILY SSF52467 286 460 1.61E-67 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MADE_1019510 d8a83470609c5dba4e9c0363017ce7d4 462 Pfam PF02233 NAD(P) transhydrogenase beta subunit 9 457 3.0E-179 T 13-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MADE_1019510 d8a83470609c5dba4e9c0363017ce7d4 462 PIRSF PIRSF000204 4 461 4.7E-172 T 13-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 MADE_1019510 d8a83470609c5dba4e9c0363017ce7d4 462 Gene3D G3DSA:3.40.50.1220 278 460 4.5E-80 T 13-10-2018 MADE_000001020860 65d7662aeb08bf64079bf7e07755d32e 84 SUPERFAMILY SSF56954 3 84 8.24E-8 T 13-10-2018 MADE_000001020860 65d7662aeb08bf64079bf7e07755d32e 84 Gene3D G3DSA:1.20.1600.10 1 84 6.6E-8 T 13-10-2018 MADE_1018950 ab42f181755f147eee480272e7030992 133 Gene3D G3DSA:3.30.70.60 1 92 1.7E-31 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MADE_1018950 ab42f181755f147eee480272e7030992 133 SUPERFAMILY SSF54995 1 104 1.09E-36 T 13-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018950 ab42f181755f147eee480272e7030992 133 Pfam PF01250 Ribosomal protein S6 3 91 7.5E-26 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018950 ab42f181755f147eee480272e7030992 133 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.0E-33 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018950 ab42f181755f147eee480272e7030992 133 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 22.04 T 13-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 MADE_1007885 04580dc7ef65abd3bac85c9101beafc3 164 Gene3D G3DSA:2.40.160.20 9 162 3.3E-6 T 13-10-2018 MADE_1007885 04580dc7ef65abd3bac85c9101beafc3 164 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 100 163 3.3E-9 T 13-10-2018 IPR018550 Lipid A 3-O-deacylase-related MADE_1006710 cc88c94656c35f65882fce503b938853 297 Pfam PF11227 Protein of unknown function (DUF3025) 68 284 8.7E-69 T 13-10-2018 IPR021390 Protein of unknown function DUF3025 MADE_1014905 ac4298e050e94346db16412e0a6c46a9 229 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 27 219 3.5E-44 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MADE_1014905 ac4298e050e94346db16412e0a6c46a9 229 SUPERFAMILY SSF100950 26 226 2.93E-50 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1014905 ac4298e050e94346db16412e0a6c46a9 229 PIRSF PIRSF006806 22 222 2.3E-33 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MADE_1014905 ac4298e050e94346db16412e0a6c46a9 229 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 29 219 8.6E-35 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase MADE_1014905 ac4298e050e94346db16412e0a6c46a9 229 Gene3D G3DSA:3.40.50.10420 25 228 3.1E-50 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily MADE_1015520 b6eea7dc1711dcf42c2ed0820276954d 351 Pfam PF01758 Sodium Bile acid symporter family 47 252 3.1E-45 T 13-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MADE_1015520 b6eea7dc1711dcf42c2ed0820276954d 351 Gene3D G3DSA:1.20.1530.20 2 342 2.0E-29 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily MADE_1015520 b6eea7dc1711dcf42c2ed0820276954d 351 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 1 340 6.6E-127 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MADE_1015520 b6eea7dc1711dcf42c2ed0820276954d 351 PIRSF PIRSF005508 1 351 3.8E-127 T 13-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 MADE_1000215 626d21d86993068aaf1a8068a52af229 545 Gene3D G3DSA:3.40.630.10 25 110 4.0E-6 T 13-10-2018 MADE_1000215 626d21d86993068aaf1a8068a52af229 545 SUPERFAMILY SSF52025 122 248 1.57E-12 T 13-10-2018 MADE_1000215 626d21d86993068aaf1a8068a52af229 545 SUPERFAMILY SSF53187 32 527 4.61E-67 T 13-10-2018 MADE_1000215 626d21d86993068aaf1a8068a52af229 545 Gene3D G3DSA:3.50.30.30 111 259 7.3E-6 T 13-10-2018 MADE_1000215 626d21d86993068aaf1a8068a52af229 545 Pfam PF04389 Peptidase family M28 299 518 1.4E-43 T 13-10-2018 IPR007484 Peptidase M28 MADE_1000215 626d21d86993068aaf1a8068a52af229 545 Gene3D G3DSA:3.40.630.10 260 533 5.9E-52 T 13-10-2018 MADE_1000215 626d21d86993068aaf1a8068a52af229 545 Pfam PF02225 PA domain 131 205 1.8E-5 T 13-10-2018 IPR003137 PA domain MADE_1008810 18370a440245a38848a77a6b259a646c 255 Gene3D G3DSA:3.40.225.10 8 255 6.3E-67 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MADE_1008810 18370a440245a38848a77a6b259a646c 255 SUPERFAMILY SSF53639 16 222 4.12E-55 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MADE_1008810 18370a440245a38848a77a6b259a646c 255 SMART SM01007 22 201 2.3E-52 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal MADE_1008810 18370a440245a38848a77a6b259a646c 255 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 201 2.8E-40 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal MADE_1014100 f4095c4586824cb12ab397fcc43c5d9b 182 SUPERFAMILY SSF54593 20 168 1.75E-33 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1014100 f4095c4586824cb12ab397fcc43c5d9b 182 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 25 166 1.2E-19 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_1014100 f4095c4586824cb12ab397fcc43c5d9b 182 ProSitePatterns PS00934 Glyoxalase I signature 1. 26 47 - T 13-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MADE_1014100 f4095c4586824cb12ab397fcc43c5d9b 182 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 12 175 3.0E-49 T 13-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MADE_1014100 f4095c4586824cb12ab397fcc43c5d9b 182 Gene3D G3DSA:3.10.180.10 2 175 2.8E-60 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1014325 ef0f92eb188c7aec40bbbf85fbe4ce9a 331 Gene3D G3DSA:2.40.160.10 117 325 2.2E-6 T 13-10-2018 IPR023614 Porin domain superfamily MADE_1014325 ef0f92eb188c7aec40bbbf85fbe4ce9a 331 Pfam PF07642 Putative beta-barrel porin-2, OmpL-like. bbp2 79 314 2.2E-11 T 13-10-2018 IPR011486 Putative beta-barrel porin-2, OmpL-like. bbp2 MADE_1014325 ef0f92eb188c7aec40bbbf85fbe4ce9a 331 SUPERFAMILY SSF56935 34 320 4.88E-24 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 Pfam PF00117 Glutamine amidotransferase class-I 10 198 6.0E-43 T 13-10-2018 IPR017926 Glutamine amidotransferase MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 Gene3D G3DSA:3.40.50.880 7 202 1.1E-53 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00097 Anthranilate synthase component II signature 8 22 7.8E-34 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00097 Anthranilate synthase component II signature 59 68 7.8E-34 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00097 Anthranilate synthase component II signature 111 119 7.8E-34 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00097 Anthranilate synthase component II signature 131 143 7.8E-34 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00097 Anthranilate synthase component II signature 86 97 7.8E-34 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00097 Anthranilate synthase component II signature 178 191 7.8E-34 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 86 102 6.1E-5 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 56 70 6.1E-5 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 8 198 1.2E-50 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 SUPERFAMILY SSF52317 7 201 1.59E-42 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00096 Glutamine amidotransferase superfamily signature 59 68 9.6E-14 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00096 Glutamine amidotransferase superfamily signature 178 191 9.6E-14 T 13-10-2018 MADE_1006895 d72798e0a496bf66094d3509ebd7b5ca 210 PRINTS PR00096 Glutamine amidotransferase superfamily signature 86 97 9.6E-14 T 13-10-2018 MADE_1016585 267160fd7695c6857487070769372b15 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.8E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1016585 267160fd7695c6857487070769372b15 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.8E-7 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1016585 267160fd7695c6857487070769372b15 243 SMART SM00345 10 69 5.3E-22 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1016585 267160fd7695c6857487070769372b15 243 SMART SM00895 86 208 2.6E-22 T 13-10-2018 IPR011711 GntR, C-terminal MADE_1016585 267160fd7695c6857487070769372b15 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 69 1.3E-19 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1016585 267160fd7695c6857487070769372b15 243 Gene3D G3DSA:1.10.10.10 1 76 3.0E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016585 267160fd7695c6857487070769372b15 243 Pfam PF07729 FCD domain 86 207 3.8E-22 T 13-10-2018 IPR011711 GntR, C-terminal MADE_1016585 267160fd7695c6857487070769372b15 243 Gene3D G3DSA:1.20.120.530 85 217 7.7E-24 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1016585 267160fd7695c6857487070769372b15 243 SUPERFAMILY SSF48008 84 215 3.14E-23 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1016585 267160fd7695c6857487070769372b15 243 SUPERFAMILY SSF46785 3 73 3.13E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1007075 f39c95a1d14d8a2d2df432cf7dfef617 634 ProSitePatterns PS00455 Putative AMP-binding domain signature. 236 247 - T 13-10-2018 IPR020845 AMP-binding, conserved site MADE_1007075 f39c95a1d14d8a2d2df432cf7dfef617 634 Gene3D G3DSA:3.40.50.12780 30 493 2.5E-103 T 13-10-2018 MADE_1007075 f39c95a1d14d8a2d2df432cf7dfef617 634 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 3 56 1.4E-14 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 MADE_1007075 f39c95a1d14d8a2d2df432cf7dfef617 634 SUPERFAMILY SSF56801 9 613 4.19E-155 T 13-10-2018 MADE_1007075 f39c95a1d14d8a2d2df432cf7dfef617 634 Gene3D G3DSA:3.30.300.30 496 625 4.8E-26 T 13-10-2018 MADE_1007075 f39c95a1d14d8a2d2df432cf7dfef617 634 Pfam PF00501 AMP-binding enzyme 64 500 3.6E-82 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_1007075 f39c95a1d14d8a2d2df432cf7dfef617 634 Pfam PF13193 AMP-binding enzyme C-terminal domain 509 588 3.8E-24 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 SUPERFAMILY SSF63411 277 465 9.25E-35 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Gene3D G3DSA:3.30.830.10 43 268 7.7E-69 T 13-10-2018 MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Gene3D G3DSA:3.30.830.10 736 931 1.1E-32 T 13-10-2018 MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Gene3D G3DSA:3.30.830.10 521 728 2.9E-42 T 13-10-2018 MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 SUPERFAMILY SSF63411 47 255 4.89E-56 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 SUPERFAMILY SSF63411 514 719 6.83E-45 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Pfam PF05193 Peptidase M16 inactive domain 216 393 7.4E-27 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Pfam PF05193 Peptidase M16 inactive domain 683 860 4.9E-26 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Pfam PF00675 Insulinase (Peptidase family M16) 535 655 4.2E-13 T 13-10-2018 IPR011765 Peptidase M16, N-terminal MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Pfam PF00675 Insulinase (Peptidase family M16) 59 177 1.5E-18 T 13-10-2018 IPR011765 Peptidase M16, N-terminal MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 Gene3D G3DSA:3.30.830.10 270 471 1.6E-36 T 13-10-2018 MADE_1006490 45fa74baf1fb98c22701812f8fe8521e 956 SUPERFAMILY SSF63411 739 939 1.15E-34 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_1006190 a4cea5c3ca81036370e7c8945489b3d7 217 Gene3D G3DSA:1.20.1050.10 90 217 8.7E-50 T 13-10-2018 MADE_1006190 a4cea5c3ca81036370e7c8945489b3d7 217 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 83 6.3E-17 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_1006190 a4cea5c3ca81036370e7c8945489b3d7 217 Gene3D G3DSA:3.40.30.10 5 84 1.1E-27 T 13-10-2018 MADE_1006190 a4cea5c3ca81036370e7c8945489b3d7 217 SUPERFAMILY SSF47616 87 215 7.11E-29 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1006190 a4cea5c3ca81036370e7c8945489b3d7 217 SUPERFAMILY SSF52833 2 90 4.49E-24 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1006190 a4cea5c3ca81036370e7c8945489b3d7 217 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 4 216 1.9E-87 T 13-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 MADE_1000330 36a753dcef6e562993b1887e3a2ea593 301 Pfam PF01694 Rhomboid family 150 295 6.1E-25 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MADE_1000330 36a753dcef6e562993b1887e3a2ea593 301 Gene3D G3DSA:1.20.1540.10 110 296 1.1E-46 T 13-10-2018 IPR035952 Rhomboid-like superfamily MADE_1000330 36a753dcef6e562993b1887e3a2ea593 301 Pfam PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease 19 91 9.7E-16 T 13-10-2018 IPR022732 Peptidase S54, GlpG peptidase, N-terminal GO:0004252|GO:0016021 MADE_1000330 36a753dcef6e562993b1887e3a2ea593 301 TIGRFAM TIGR04239 rhombo_GlpG: rhomboid family protease GlpG 19 293 7.0E-84 T 13-10-2018 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 MADE_1000330 36a753dcef6e562993b1887e3a2ea593 301 SUPERFAMILY SSF144091 112 293 1.27E-35 T 13-10-2018 MADE_000001021320 260c255f523dbc7758fe943fe1b3114a 379 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 57 373 6.8E-56 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_000001021320 260c255f523dbc7758fe943fe1b3114a 379 Gene3D G3DSA:1.10.287.470 115 174 2.1E-59 T 13-10-2018 MADE_000001021320 260c255f523dbc7758fe943fe1b3114a 379 SUPERFAMILY SSF111369 72 248 1.26E-28 T 13-10-2018 MADE_000001021320 260c255f523dbc7758fe943fe1b3114a 379 Gene3D G3DSA:2.40.50.100 81 213 2.1E-59 T 13-10-2018 MADE_000001021320 260c255f523dbc7758fe943fe1b3114a 379 Gene3D G3DSA:2.40.30.170 66 292 2.1E-59 T 13-10-2018 MADE_000001021320 260c255f523dbc7758fe943fe1b3114a 379 Pfam PF13437 HlyD family secretion protein 179 282 9.1E-8 T 13-10-2018 MADE_000001021320 260c255f523dbc7758fe943fe1b3114a 379 Gene3D G3DSA:2.40.420.20 59 372 2.1E-59 T 13-10-2018 MADE_1012945 3d92b4c4da8d899c44b0561f4d514d1c 294 Pfam PF04397 LytTr DNA-binding domain 203 289 8.1E-18 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MADE_1012945 3d92b4c4da8d899c44b0561f4d514d1c 294 Gene3D G3DSA:2.40.50.1020 189 290 7.0E-12 T 13-10-2018 MADE_1012945 3d92b4c4da8d899c44b0561f4d514d1c 294 PIRSF PIRSF031767 2 294 2.4E-49 T 13-10-2018 IPR012379 LytTR MHYE transcriptional regulator, putative MADE_1012945 3d92b4c4da8d899c44b0561f4d514d1c 294 SMART SM00850 200 294 2.0E-15 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MADE_1015865 b6b7342416f814df2abdd7ad4ec779f2 440 Gene3D G3DSA:2.40.160.180 36 434 6.5E-102 T 13-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily MADE_1015865 b6b7342416f814df2abdd7ad4ec779f2 440 Pfam PF04966 Carbohydrate-selective porin, OprB family 64 433 6.4E-73 T 13-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 MADE_1016360 b66672da4aa519e103512f1eeab8dce3 294 Gene3D G3DSA:1.10.10.10 1 88 5.4E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016360 b66672da4aa519e103512f1eeab8dce3 294 Pfam PF03466 LysR substrate binding domain 88 284 7.9E-36 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1016360 b66672da4aa519e103512f1eeab8dce3 294 Gene3D G3DSA:3.40.190.290 90 285 5.5E-32 T 13-10-2018 MADE_1016360 b66672da4aa519e103512f1eeab8dce3 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.8E-11 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1016360 b66672da4aa519e103512f1eeab8dce3 294 SUPERFAMILY SSF53850 89 289 1.09E-35 T 13-10-2018 MADE_1016360 b66672da4aa519e103512f1eeab8dce3 294 SUPERFAMILY SSF46785 2 111 3.77E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1007320 eda340384a3418677902b14d56b672d7 175 Pfam PF13302 Acetyltransferase (GNAT) domain 9 154 2.7E-25 T 13-10-2018 IPR000182 GNAT domain MADE_1007320 eda340384a3418677902b14d56b672d7 175 SUPERFAMILY SSF55729 3 156 3.88E-24 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1007320 eda340384a3418677902b14d56b672d7 175 Gene3D G3DSA:3.40.630.30 1 174 6.2E-29 T 13-10-2018 MADE_1012575 bacf3bfee4418a86997fc8a97acae03b 161 Gene3D G3DSA:2.40.10.330 71 120 8.4E-53 T 13-10-2018 MADE_1012575 bacf3bfee4418a86997fc8a97acae03b 161 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 93 4.1E-13 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MADE_1012575 bacf3bfee4418a86997fc8a97acae03b 161 SUPERFAMILY SSF54534 3 139 2.16E-34 T 13-10-2018 MADE_1012575 bacf3bfee4418a86997fc8a97acae03b 161 Gene3D G3DSA:3.10.50.40 3 153 8.4E-53 T 13-10-2018 MADE_000001022835 fef746ab7939a1866a054daf2d6ff6a7 171 Gene3D G3DSA:3.10.180.10 3 159 2.4E-23 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_000001022835 fef746ab7939a1866a054daf2d6ff6a7 171 SUPERFAMILY SSF54593 10 161 4.56E-27 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_000001022835 fef746ab7939a1866a054daf2d6ff6a7 171 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 156 2.2E-12 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_000001022835 fef746ab7939a1866a054daf2d6ff6a7 171 TIGRFAM TIGR03645 glyox_marine: lactoylglutathione lyase family protein 9 170 8.2E-104 T 13-10-2018 IPR019883 Lactoylglutathione lyase MADE_1000110 845689c523ba3f19c54ee747078f2dc4 357 SMART SM00257 36 84 9.5E-7 T 13-10-2018 IPR018392 LysM domain MADE_1000110 845689c523ba3f19c54ee747078f2dc4 357 SUPERFAMILY SSF54106 35 83 1.24E-7 T 13-10-2018 MADE_1000110 845689c523ba3f19c54ee747078f2dc4 357 Gene3D G3DSA:3.10.350.10 35 82 4.9E-14 T 13-10-2018 IPR036779 LysM domain superfamily MADE_1000110 845689c523ba3f19c54ee747078f2dc4 357 Pfam PF01476 LysM domain 37 83 5.0E-12 T 13-10-2018 IPR018392 LysM domain MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 PRINTS PR01249 Ribosomal protein L31 signature 46 64 7.3E-24 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 PRINTS PR01249 Ribosomal protein L31 signature 31 46 7.3E-24 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 7.3E-24 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 32.058 T 13-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 Pfam PF01197 Ribosomal protein L31 1 65 1.2E-32 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 1.5E-36 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 SUPERFAMILY SSF143800 1 67 1.14E-29 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018305 ef393c0dd48b1ca3ce08b597df007653 70 Gene3D G3DSA:2.30.170.50 1 70 1.1E-35 T 13-10-2018 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 SUPERFAMILY SSF52016 169 394 6.67E-31 T 13-10-2018 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 SUPERFAMILY SSF53732 402 914 3.53E-73 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Gene3D G3DSA:3.30.499.10 430 567 1.8E-113 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Gene3D G3DSA:1.25.40.310 3 168 6.0E-50 T 13-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Pfam PF00330 Aconitase family (aconitate hydratase) 411 894 1.0E-61 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Gene3D G3DSA:3.30.499.10 732 820 2.9E-8 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Gene3D G3DSA:3.30.499.10 833 921 1.2E-17 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Pfam PF06434 Aconitate hydratase 2 N-terminus 177 406 1.7E-62 T 13-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Gene3D G3DSA:3.40.1060.10 425 717 1.8E-113 T 13-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Pfam PF11791 Aconitate B N-terminal domain 6 163 3.9E-43 T 13-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 SUPERFAMILY SSF74778 3 167 4.32E-42 T 13-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 MADE_1003930 ea99b26d80d633be888b54907d7765c2 936 Gene3D G3DSA:3.20.19.10 169 385 4.6E-33 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 Gene3D G3DSA:3.55.40.10 41 207 4.9E-44 T 13-10-2018 MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 PRINTS PR00885 Bacterial general secretion pathway protein H signature 158 173 5.9E-15 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 PRINTS PR00885 Bacterial general secretion pathway protein H signature 9 23 5.9E-15 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 PRINTS PR00885 Bacterial general secretion pathway protein H signature 24 38 5.9E-15 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 SUPERFAMILY SSF54523 14 106 2.83E-9 T 13-10-2018 MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 Pfam PF07963 Prokaryotic N-terminal methylation motif 12 32 5.9E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 33 4.2E-4 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019845 dcd69775bbf0eaa4e05c881d1268a982 208 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 12 179 1.0E-14 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 MADE_1012000 52b59c64ea7f323dada0148a0faa3d7a 161 Pfam PF11158 Protein of unknown function (DUF2938) 8 156 4.8E-64 T 13-10-2018 IPR021329 Protein of unknown function DUF2938 MADE_1009550 cae65417bcd97b23fd1e3b8ec75f0221 298 Pfam PF13444 Acetyltransferase (GNAT) domain 62 160 8.7E-14 T 13-10-2018 MADE_1009550 cae65417bcd97b23fd1e3b8ec75f0221 298 Gene3D G3DSA:3.40.630.30 47 256 2.3E-43 T 13-10-2018 MADE_1009550 cae65417bcd97b23fd1e3b8ec75f0221 298 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 39 270 1.4E-58 T 13-10-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted MADE_1009550 cae65417bcd97b23fd1e3b8ec75f0221 298 SUPERFAMILY SSF55729 43 245 4.5E-24 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1012865 2a19e98c53fe3bd1ba0f468421f0346f 372 Pfam PF04055 Radical SAM superfamily 107 276 8.9E-17 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1012865 2a19e98c53fe3bd1ba0f468421f0346f 372 Gene3D G3DSA:3.20.20.70 65 336 1.9E-109 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1012865 2a19e98c53fe3bd1ba0f468421f0346f 372 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 3 351 73.32 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MADE_1012865 2a19e98c53fe3bd1ba0f468421f0346f 372 PIRSF PIRSF006004 2 364 9.6E-143 T 13-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 MADE_1012865 2a19e98c53fe3bd1ba0f468421f0346f 372 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 355 1.6E-155 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 MADE_1012865 2a19e98c53fe3bd1ba0f468421f0346f 372 Gene3D G3DSA:1.10.150.530 3 64 7.0E-27 T 13-10-2018 MADE_1012865 2a19e98c53fe3bd1ba0f468421f0346f 372 SUPERFAMILY SSF102114 103 311 5.62E-14 T 13-10-2018 MADE_1001580 c1cb240eba3bbf7130b500c360a8c4df 164 Gene3D G3DSA:3.10.450.50 40 163 1.1E-36 T 13-10-2018 MADE_1001580 c1cb240eba3bbf7130b500c360a8c4df 164 SUPERFAMILY SSF54427 53 163 1.8E-26 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1001580 c1cb240eba3bbf7130b500c360a8c4df 164 Pfam PF14534 Domain of unknown function (DUF4440) 53 157 4.6E-10 T 13-10-2018 IPR027843 Domain of unknown function DUF4440 MADE_1004835 21e4e2c8d218356173ecc37247995145 259 Pfam PF01061 ABC-2 type transporter 15 220 1.5E-15 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MADE_1004835 21e4e2c8d218356173ecc37247995145 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 198 217 5.0E-15 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1004835 21e4e2c8d218356173ecc37247995145 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 33 54 5.0E-15 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1004835 21e4e2c8d218356173ecc37247995145 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 178 197 5.0E-15 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1004835 21e4e2c8d218356173ecc37247995145 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 141 165 5.0E-15 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1004880 895443ee916ff848593e5019ed410215 536 SUPERFAMILY SSF109604 274 524 1.54E-10 T 13-10-2018 MADE_1004880 895443ee916ff848593e5019ed410215 536 Gene3D G3DSA:1.10.3210.10 270 402 1.8E-6 T 13-10-2018 MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 3 350 5.4E-106 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 SUPERFAMILY SSF52440 1 87 6.47E-15 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 Gene3D G3DSA:3.30.470.20 176 366 5.9E-73 T 13-10-2018 MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 Gene3D G3DSA:3.40.50.20 1 96 3.8E-17 T 13-10-2018 MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 347 36.297 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 Pfam PF02222 ATP-grasp domain 102 274 3.4E-47 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 Gene3D G3DSA:3.30.1490.20 97 173 3.2E-15 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 SUPERFAMILY SSF51246 299 369 4.79E-17 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MADE_1002885 331e6a2686c225e755aca8bbfae63645 378 SUPERFAMILY SSF56059 92 295 5.13E-56 T 13-10-2018 MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 Pfam PF01047 MarR family 35 93 9.3E-11 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 SUPERFAMILY SSF46785 9 144 1.29E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.1E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.1E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.1E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.1E-12 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 SMART SM00347 28 129 1.5E-16 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_000001020920 850d7dc125f75ad1758095211dfb8146 151 Gene3D G3DSA:1.10.10.10 10 147 3.6E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1001890 0e3a68180a2d7edfeee6e3a57823d7a6 297 Pfam PF05425 Copper resistance protein D 192 288 5.7E-17 T 13-10-2018 IPR008457 Copper resistance protein D GO:0016021 MADE_1019365 b32eb938c7e43239f69d52177d67d7ed 194 Gene3D G3DSA:3.30.1050.10 87 173 3.2E-7 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MADE_1019365 b32eb938c7e43239f69d52177d67d7ed 194 SUPERFAMILY SSF55718 69 171 2.83E-16 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily MADE_1019365 b32eb938c7e43239f69d52177d67d7ed 194 Pfam PF02036 SCP-2 sterol transfer family 65 167 1.1E-13 T 13-10-2018 IPR003033 SCP2 sterol-binding domain MADE_1001250 a7d924e67cac249c01e5357159094b10 411 Pfam PF00482 Type II secretion system (T2SS), protein F 75 198 2.2E-29 T 13-10-2018 IPR018076 Type II secretion system F domain MADE_1001250 a7d924e67cac249c01e5357159094b10 411 Pfam PF00482 Type II secretion system (T2SS), protein F 279 400 2.5E-24 T 13-10-2018 IPR018076 Type II secretion system F domain MADE_1001250 a7d924e67cac249c01e5357159094b10 411 Gene3D G3DSA:1.20.81.30 261 373 1.6E-25 T 13-10-2018 MADE_1001250 a7d924e67cac249c01e5357159094b10 411 Gene3D G3DSA:1.20.81.30 60 178 3.6E-29 T 13-10-2018 MADE_1001250 a7d924e67cac249c01e5357159094b10 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 71 83 1.7E-9 T 13-10-2018 IPR003004 GspF/PilC family MADE_1001250 a7d924e67cac249c01e5357159094b10 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 170 198 1.7E-9 T 13-10-2018 IPR003004 GspF/PilC family MADE_1001250 a7d924e67cac249c01e5357159094b10 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 389 408 1.7E-9 T 13-10-2018 IPR003004 GspF/PilC family MADE_1001250 a7d924e67cac249c01e5357159094b10 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 373 387 1.7E-9 T 13-10-2018 IPR003004 GspF/PilC family MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 Gene3D G3DSA:1.10.246.130 258 372 4.5E-33 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 371 395 - T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 Gene3D G3DSA:3.60.20.40 373 555 2.3E-64 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 36 547 4.5E-158 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 SUPERFAMILY SSF56235 31 547 1.24E-167 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 127 145 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 55 80 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 145 164 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 460 477 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 436 451 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 395 413 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 242 258 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 371 389 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 272 291 1.3E-71 T 13-10-2018 MADE_1002955 2f26e6f46a15b80f0c377c80478c4075 560 Pfam PF01019 Gamma-glutamyltranspeptidase 48 550 2.2E-165 T 13-10-2018 MADE_1002485 98840cae965fc403b69ce0240170acc1 179 Pfam PF07700 Haem-NO-binding 3 159 4.0E-35 T 13-10-2018 IPR011644 Heme NO-binding GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 MADE_1002485 98840cae965fc403b69ce0240170acc1 179 SUPERFAMILY SSF111126 1 165 1.62E-36 T 13-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily MADE_1002485 98840cae965fc403b69ce0240170acc1 179 Gene3D G3DSA:3.90.1520.10 1 178 1.6E-50 T 13-10-2018 IPR038158 H-NOX domain superfamily GO:0020037 KEGG: 00230+4.6.1.2|Reactome: R-HSA-392154 MADE_1019480 c6f16d7bf7c66b76837d189ff3437ae7 294 SUPERFAMILY SSF103481 185 280 3.14E-14 T 13-10-2018 MADE_1019480 c6f16d7bf7c66b76837d189ff3437ae7 294 Pfam PF00892 EamA-like transporter family 149 280 1.3E-20 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1019480 c6f16d7bf7c66b76837d189ff3437ae7 294 Pfam PF00892 EamA-like transporter family 6 136 8.1E-21 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1019480 c6f16d7bf7c66b76837d189ff3437ae7 294 SUPERFAMILY SSF103481 38 138 1.83E-16 T 13-10-2018 MADE_1011520 450c64a3cd8a47ce4c2a6779875b8dd4 249 Pfam PF05239 PRC-barrel domain 147 204 1.2E-4 T 13-10-2018 IPR027275 PRC-barrel domain MADE_1011520 450c64a3cd8a47ce4c2a6779875b8dd4 249 Gene3D G3DSA:3.90.50.10 6 113 4.1E-14 T 13-10-2018 IPR014747 Bacterial photosynthetic reaction centre, H-chain, C-terminal GO:0019684|GO:0030077|GO:0045156 MADE_1011520 450c64a3cd8a47ce4c2a6779875b8dd4 249 Gene3D G3DSA:2.30.30.240 132 224 1.3E-9 T 13-10-2018 MADE_1011520 450c64a3cd8a47ce4c2a6779875b8dd4 249 SUPERFAMILY SSF50346 2 114 1.82E-21 T 13-10-2018 IPR011033 PRC-barrel-like superfamily MADE_1011520 450c64a3cd8a47ce4c2a6779875b8dd4 249 SUPERFAMILY SSF50346 139 242 9.03E-17 T 13-10-2018 IPR011033 PRC-barrel-like superfamily MADE_1002580 a097a24b6f8329f717f6d8f6e1814303 203 PIRSF PIRSF016482 4 203 4.3E-56 T 13-10-2018 IPR007445 Pilus assembly protein, PilO MADE_1002580 a097a24b6f8329f717f6d8f6e1814303 203 Pfam PF04350 Pilus assembly protein, PilO 56 192 4.3E-51 T 13-10-2018 IPR007445 Pilus assembly protein, PilO MADE_1002580 a097a24b6f8329f717f6d8f6e1814303 203 Gene3D G3DSA:1.10.287.540 62 98 3.2E-7 T 13-10-2018 MADE_1002580 a097a24b6f8329f717f6d8f6e1814303 203 Gene3D G3DSA:3.30.70.60 99 202 3.2E-35 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 SUPERFAMILY SSF56645 2 264 3.27E-61 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 Gene3D G3DSA:2.40.110.10 137 251 6.7E-38 T 13-10-2018 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 Gene3D G3DSA:1.20.140.10 252 406 6.4E-39 T 13-10-2018 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 399 1.5E-32 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 Gene3D G3DSA:1.10.540.10 1 136 2.4E-48 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 239 1.3E-17 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 134 3.5E-16 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 MADE_1000660 152e81754e6c65221d99272a0fe164c3 406 SUPERFAMILY SSF47203 250 405 4.51E-44 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 MADE_000001021735 3bc03ce4a6c31ce31752af6bbde350ce 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.3E-29 T 13-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 MADE_000001021735 3bc03ce4a6c31ce31752af6bbde350ce 72 SMART SM00316 4 72 5.0E-6 T 13-10-2018 IPR022967 RNA-binding domain, S1 MADE_000001021735 3bc03ce4a6c31ce31752af6bbde350ce 72 Gene3D G3DSA:2.40.50.140 1 72 9.3E-38 T 13-10-2018 MADE_000001021735 3bc03ce4a6c31ce31752af6bbde350ce 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.423 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MADE_000001021735 3bc03ce4a6c31ce31752af6bbde350ce 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.9E-39 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 MADE_000001021735 3bc03ce4a6c31ce31752af6bbde350ce 72 SUPERFAMILY SSF50249 1 70 2.69E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1007600 9faa27616a632df12041abd92a11497e 208 Pfam PF03550 Outer membrane lipoprotein LolB 43 206 5.8E-35 T 13-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MADE_1007600 9faa27616a632df12041abd92a11497e 208 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 2 207 4.7E-28 T 13-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 MADE_1007600 9faa27616a632df12041abd92a11497e 208 SUPERFAMILY SSF89392 17 207 3.1E-31 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX MADE_1007600 9faa27616a632df12041abd92a11497e 208 Gene3D G3DSA:2.50.20.10 23 208 1.0E-40 T 13-10-2018 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 SUPERFAMILY SSF55021 4 85 8.78E-15 T 13-10-2018 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 SUPERFAMILY SSF53328 89 283 1.18E-55 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 2 283 45.124 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 6 283 2.7E-104 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 257 282 2.6E-55 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 7 33 2.6E-55 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 89 111 2.6E-55 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 2.6E-55 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 235 257 2.6E-55 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 111 138 2.6E-55 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 Pfam PF00551 Formyl transferase 89 262 1.3E-35 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 Gene3D G3DSA:3.40.50.170 88 284 1.4E-68 T 13-10-2018 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 PIRSF PIRSF036480 2 284 4.4E-111 T 13-10-2018 MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 Pfam PF01842 ACT domain 6 58 1.8E-7 T 13-10-2018 IPR002912 ACT domain MADE_1002370 fd8951e25ddec8fd19359e371dde38b3 284 Gene3D G3DSA:3.30.70.260 1 87 2.9E-25 T 13-10-2018 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 Gene3D G3DSA:1.10.8.540 509 598 6.1E-25 T 13-10-2018 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 Pfam PF00771 FHIPEP family 31 689 5.6E-261 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 Gene3D G3DSA:3.40.30.60 365 508 5.8E-51 T 13-10-2018 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 Gene3D G3DSA:1.10.490.80 600 697 1.3E-12 T 13-10-2018 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 3.5E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 3.5E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 3.5E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 3.5E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 3.5E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 3.5E-54 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 24 697 3.0E-258 T 13-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 13-10-2018 IPR025505 FHIPEP conserved site MADE_1005970 1543ff5f9d41e770b126239e98d3d675 699 PIRSF PIRSF005419 7 699 8.6E-242 T 13-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 MADE_1013420 6cccbb9068da3ce78dc0cc67c4171f7f 447 SMART SM00471 59 264 2.3E-8 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1013420 6cccbb9068da3ce78dc0cc67c4171f7f 447 Pfam PF13286 Phosphohydrolase-associated domain 341 431 9.6E-27 T 13-10-2018 IPR026875 Phosphohydrolase-associated domain MADE_1013420 6cccbb9068da3ce78dc0cc67c4171f7f 447 SUPERFAMILY SSF109604 24 437 4.34E-79 T 13-10-2018 MADE_1013420 6cccbb9068da3ce78dc0cc67c4171f7f 447 Pfam PF01966 HD domain 63 145 3.2E-9 T 13-10-2018 IPR006674 HD domain MADE_1013420 6cccbb9068da3ce78dc0cc67c4171f7f 447 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 25 435 8.8E-117 T 13-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 MADE_1013420 6cccbb9068da3ce78dc0cc67c4171f7f 447 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 1 434 33.618 T 13-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 SUPERFAMILY SSF81333 2 70 2.62E-18 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 PRINTS PR00124 ATP synthase C subunit signature 43 68 3.4E-9 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 PRINTS PR00124 ATP synthase C subunit signature 5 24 3.4E-9 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 PRINTS PR00124 ATP synthase C subunit signature 26 41 3.4E-9 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 14.683 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 Pfam PF00137 ATP synthase subunit C 4 67 1.9E-11 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 13-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 70 7.7E-31 T 13-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MADE_1020480 c2cb081d43588912a409c3811c7f2a80 73 Gene3D G3DSA:1.20.20.10 1 72 4.4E-29 T 13-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 Gene3D G3DSA:1.10.287.130 191 310 5.5E-15 T 13-10-2018 MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 1.5E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 1.5E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 1.5E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 Gene3D G3DSA:3.30.565.10 322 469 1.5E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 SUPERFAMILY SSF55874 319 465 2.62E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 466 2.5E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 SMART SM00388 247 315 1.1E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 SMART SM00387 356 468 3.1E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 310 1.4E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_000001021130 aa7569fe09e2a1ca61fb0a947c6567ba 469 SUPERFAMILY SSF47384 234 309 4.12E-14 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1010290 11521c7ecbdcf87df1b7391879a78653 454 Pfam PF02321 Outer membrane efflux protein 270 433 1.1E-14 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1010290 11521c7ecbdcf87df1b7391879a78653 454 Pfam PF02321 Outer membrane efflux protein 69 235 2.4E-12 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1010290 11521c7ecbdcf87df1b7391879a78653 454 SUPERFAMILY SSF56954 44 439 6.8E-43 T 13-10-2018 MADE_1010290 11521c7ecbdcf87df1b7391879a78653 454 Gene3D G3DSA:1.20.1600.10 66 441 3.3E-32 T 13-10-2018 MADE_1006445 8cc53dd655dfccdce9ded60537cbfedd 145 Pfam PF09945 Predicted membrane protein (DUF2177) 13 133 6.1E-36 T 13-10-2018 IPR018687 Protein of unknown function DUF2177, membrane MADE_000001023420 9163ce4c39b7095b5681e75e16cfea2e 227 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 51 226 5.8E-72 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MADE_000001023420 9163ce4c39b7095b5681e75e16cfea2e 227 Gene3D G3DSA:1.10.286.10 11 97 5.2E-32 T 13-10-2018 MADE_000001023420 9163ce4c39b7095b5681e75e16cfea2e 227 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 47 227 29.76 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MADE_000001023420 9163ce4c39b7095b5681e75e16cfea2e 227 Pfam PF01227 GTP cyclohydrolase I 51 226 2.1E-57 T 13-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MADE_000001023420 9163ce4c39b7095b5681e75e16cfea2e 227 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 157 167 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 MADE_000001023420 9163ce4c39b7095b5681e75e16cfea2e 227 Gene3D G3DSA:3.30.1130.10 98 227 1.1E-46 T 13-10-2018 MADE_000001023420 9163ce4c39b7095b5681e75e16cfea2e 227 SUPERFAMILY SSF55620 23 226 7.34E-69 T 13-10-2018 MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 Pfam PF00271 Helicase conserved C-terminal domain 233 341 1.4E-28 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 Pfam PF00270 DEAD/DEAH box helicase 32 197 6.8E-51 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 Pfam PF03880 DbpA RNA binding domain 485 555 1.0E-22 T 13-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 2 557 44.94 T 13-10-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 Gene3D G3DSA:3.30.70.330 485 557 1.1E-12 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 Gene3D G3DSA:3.40.50.300 7 213 2.1E-77 T 13-10-2018 MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 SUPERFAMILY SSF52540 5 210 3.81E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 SMART SM00487 26 224 1.4E-63 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 Gene3D G3DSA:3.40.50.300 216 437 2.7E-50 T 13-10-2018 MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 SUPERFAMILY SSF52540 148 355 5.55E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003525 c812731883bdd1bce756d9f7fa02329e 589 SMART SM00490 260 341 2.1E-33 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1018220 ed58f76cbcdb0c9a6b136ae831ece8a1 660 SUPERFAMILY SSF56436 404 657 1.41E-43 T 13-10-2018 IPR016187 C-type lectin fold MADE_1018220 ed58f76cbcdb0c9a6b136ae831ece8a1 660 Pfam PF03781 Sulfatase-modifying factor enzyme 1 414 657 2.1E-35 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 MADE_1018220 ed58f76cbcdb0c9a6b136ae831ece8a1 660 Gene3D G3DSA:3.90.1580.10 400 657 6.2E-45 T 13-10-2018 MADE_1018220 ed58f76cbcdb0c9a6b136ae831ece8a1 660 Pfam PF08308 PEGA domain 184 250 1.8E-13 T 13-10-2018 IPR013229 PEGA MADE_1018220 ed58f76cbcdb0c9a6b136ae831ece8a1 660 Pfam PF08308 PEGA domain 326 381 3.8E-10 T 13-10-2018 IPR013229 PEGA MADE_1007355 73d69784e764a8b6ea92d1d349af54ba 836 Gene3D G3DSA:2.170.130.10 32 176 5.7E-18 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1007355 73d69784e764a8b6ea92d1d349af54ba 836 SUPERFAMILY SSF56935 28 835 4.27E-84 T 13-10-2018 MADE_1007355 73d69784e764a8b6ea92d1d349af54ba 836 Pfam PF00593 TonB dependent receptor 407 833 9.9E-22 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1007355 73d69784e764a8b6ea92d1d349af54ba 836 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 167 2.0E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1016950 227290c52856cc0e97c03098df9b2608 304 SMART SM00563 88 230 7.4E-23 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1016950 227290c52856cc0e97c03098df9b2608 304 Pfam PF01553 Acyltransferase 75 227 3.3E-17 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1016950 227290c52856cc0e97c03098df9b2608 304 SUPERFAMILY SSF69593 29 295 3.27E-37 T 13-10-2018 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PRINTS PR00601 Bacterioferritin signature 107 127 5.0E-47 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PRINTS PR00601 Bacterioferritin signature 23 43 5.0E-47 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PRINTS PR00601 Bacterioferritin signature 44 64 5.0E-47 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PRINTS PR00601 Bacterioferritin signature 3 22 5.0E-47 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PRINTS PR00601 Bacterioferritin signature 129 150 5.0E-47 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PRINTS PR00601 Bacterioferritin signature 65 85 5.0E-47 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PRINTS PR00601 Bacterioferritin signature 86 106 5.0E-47 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 Pfam PF00210 Ferritin-like domain 8 145 2.6E-37 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 SUPERFAMILY SSF47240 1 155 3.54E-45 T 13-10-2018 IPR009078 Ferritin-like superfamily MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 3.3E-48 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 Gene3D G3DSA:1.20.1260.10 1 155 2.0E-59 T 13-10-2018 IPR012347 Ferritin-like MADE_1010400 106c58a39f11dfc22e8b4096fb533da0 155 PIRSF PIRSF002560 1 155 1.6E-60 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 SUPERFAMILY SSF54106 432 475 3.66E-10 T 13-10-2018 MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 SUPERFAMILY SSF53187 189 414 7.22E-51 T 13-10-2018 MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 SMART SM00646 251 410 1.6E-48 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 Pfam PF01476 LysM domain 433 475 4.6E-11 T 13-10-2018 IPR018392 LysM domain MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 Gene3D G3DSA:2.60.40.3500 45 160 3.5E-27 T 13-10-2018 MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 Gene3D G3DSA:3.40.630.40 178 418 1.6E-71 T 13-10-2018 MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 SMART SM00257 432 475 4.4E-14 T 13-10-2018 IPR018392 LysM domain MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 191 408 1.3E-45 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 Gene3D G3DSA:3.10.350.10 428 477 9.4E-15 T 13-10-2018 IPR036779 LysM domain superfamily MADE_000001023565 37eaea5d4bf6625cd3014211f4fff68b 477 Pfam PF11741 AMIN domain 58 158 1.3E-19 T 13-10-2018 IPR021731 AMIN domain MADE_1015875 6a713574ecadde11468413b117df9c1f 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 140 1.8E-20 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like MADE_1015875 6a713574ecadde11468413b117df9c1f 148 Gene3D G3DSA:3.30.530.20 1 145 6.1E-32 T 13-10-2018 IPR023393 START-like domain superfamily MADE_1015875 6a713574ecadde11468413b117df9c1f 148 SUPERFAMILY SSF55961 1 140 1.98E-30 T 13-10-2018 MADE_1010065 f9ed23a3ec35da42533576ed037bd233 368 Hamap MF_02040 Iron-sulfur cluster carrier protein. 91 340 36.207 T 13-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein MADE_1010065 f9ed23a3ec35da42533576ed037bd233 368 ProSitePatterns PS01215 Mrp family signature. 203 219 - T 13-10-2018 IPR000808 Mrp, conserved site GO:0005524 MADE_1010065 f9ed23a3ec35da42533576ed037bd233 368 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 339 4.8E-98 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MADE_1010065 f9ed23a3ec35da42533576ed037bd233 368 Gene3D G3DSA:3.40.50.300 87 336 4.4E-80 T 13-10-2018 MADE_1010065 f9ed23a3ec35da42533576ed037bd233 368 SUPERFAMILY SSF52540 98 340 4.24E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 PIRSF PIRSF000077 2 108 5.0E-44 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 Pfam PF00085 Thioredoxin 5 106 7.1E-34 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 PRINTS PR00421 Thioredoxin family signature 24 32 3.3E-10 T 13-10-2018 MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 PRINTS PR00421 Thioredoxin family signature 72 83 3.3E-10 T 13-10-2018 MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 PRINTS PR00421 Thioredoxin family signature 32 41 3.3E-10 T 13-10-2018 MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 SUPERFAMILY SSF52833 2 108 1.8E-40 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 5.3E-39 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 MADE_1002855 f2bf0c8305a4cf325b8a31484136d634 108 Gene3D G3DSA:3.40.30.10 1 108 5.6E-37 T 13-10-2018 MADE_1000760 f67c636d86d352e976a568c6a53be120 213 SUPERFAMILY SSF52540 6 195 2.33E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000760 f67c636d86d352e976a568c6a53be120 213 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 189 3.7E-73 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MADE_1000760 f67c636d86d352e976a568c6a53be120 213 SMART SM00072 5 192 1.4E-69 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MADE_1000760 f67c636d86d352e976a568c6a53be120 213 Pfam PF00625 Guanylate kinase 8 190 5.6E-59 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit MADE_1000760 f67c636d86d352e976a568c6a53be120 213 Hamap MF_00328 Guanylate kinase [gmk]. 4 192 36.928 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 MADE_1000760 f67c636d86d352e976a568c6a53be120 213 Gene3D G3DSA:3.40.50.300 10 188 4.4E-70 T 13-10-2018 MADE_1000760 f67c636d86d352e976a568c6a53be120 213 Gene3D G3DSA:3.30.63.10 42 101 4.4E-70 T 13-10-2018 MADE_1000760 f67c636d86d352e976a568c6a53be120 213 ProSitePatterns PS00856 Guanylate kinase-like signature. 45 62 - T 13-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 MADE_1011925 4d7912b0afa0d88a169cd4bd4f24669a 251 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 19 198 4.0E-43 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal MADE_1011925 4d7912b0afa0d88a169cd4bd4f24669a 251 SMART SM01007 18 198 7.3E-61 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal MADE_1011925 4d7912b0afa0d88a169cd4bd4f24669a 251 SUPERFAMILY SSF53639 12 218 2.75E-59 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MADE_1011925 4d7912b0afa0d88a169cd4bd4f24669a 251 Gene3D G3DSA:3.40.225.10 3 251 6.2E-72 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily MADE_1009830 b360a3fffb8dc976b9bb340093a984ff 217 Pfam PF01144 Coenzyme A transferase 5 200 1.8E-42 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MADE_1009830 b360a3fffb8dc976b9bb340093a984ff 217 Gene3D G3DSA:3.40.1080.10 1 212 1.1E-98 T 13-10-2018 MADE_1009830 b360a3fffb8dc976b9bb340093a984ff 217 SMART SM00882 5 201 8.6E-74 T 13-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 MADE_1009830 b360a3fffb8dc976b9bb340093a984ff 217 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 207 5.9E-99 T 13-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 MADE_1009830 b360a3fffb8dc976b9bb340093a984ff 217 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 43 51 - T 13-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 MADE_1009830 b360a3fffb8dc976b9bb340093a984ff 217 SUPERFAMILY SSF100950 4 216 9.27E-74 T 13-10-2018 IPR037171 NagB/RpiA transferase-like MADE_1007810 b1da05687e8b62d82901e8780787bdde 357 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 160 277 6.5E-18 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_1007810 b1da05687e8b62d82901e8780787bdde 357 SUPERFAMILY SSF54593 5 342 1.59E-81 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1007810 b1da05687e8b62d82901e8780787bdde 357 PIRSF PIRSF009283 1 356 3.2E-111 T 13-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MADE_1007810 b1da05687e8b62d82901e8780787bdde 357 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 5 143 1.5E-66 T 13-10-2018 MADE_1007810 b1da05687e8b62d82901e8780787bdde 357 Gene3D G3DSA:3.10.180.10 155 356 6.4E-69 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1007810 b1da05687e8b62d82901e8780787bdde 357 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 13 355 7.7E-119 T 13-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 MADE_1007810 b1da05687e8b62d82901e8780787bdde 357 Gene3D G3DSA:3.10.180.10 2 154 1.7E-47 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1019525 5bc11ab79628a4a6cba2034604460efd 968 Pfam PF00593 TonB dependent receptor 488 965 1.4E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1019525 5bc11ab79628a4a6cba2034604460efd 968 TIGRFAM TIGR01782 TonB-Xanth-Caul: TonB-dependent receptor 36 968 4.1E-203 T 13-10-2018 IPR010104 Bacterial TonB-dependent receptor MADE_1019525 5bc11ab79628a4a6cba2034604460efd 968 SUPERFAMILY SSF56935 24 968 4.93E-92 T 13-10-2018 MADE_1019525 5bc11ab79628a4a6cba2034604460efd 968 Gene3D G3DSA:2.170.130.10 37 161 8.7E-18 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1019525 5bc11ab79628a4a6cba2034604460efd 968 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 156 1.7E-18 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1012590 57dccfe0c2cabe10cfd9212130d7dda2 200 SUPERFAMILY SSF54523 27 114 1.26E-15 T 13-10-2018 MADE_1012590 57dccfe0c2cabe10cfd9212130d7dda2 200 Gene3D G3DSA:3.30.700.10 27 172 7.6E-10 T 13-10-2018 MADE_1012590 57dccfe0c2cabe10cfd9212130d7dda2 200 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 24 44 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012590 57dccfe0c2cabe10cfd9212130d7dda2 200 Pfam PF07963 Prokaryotic N-terminal methylation motif 23 45 4.3E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012590 57dccfe0c2cabe10cfd9212130d7dda2 200 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 23 45 1.1E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012590 57dccfe0c2cabe10cfd9212130d7dda2 200 Pfam PF12019 Type II transport protein GspH 63 163 3.0E-12 T 13-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 Gene3D G3DSA:3.40.50.1100 9 204 4.4E-180 T 13-10-2018 MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 PIRSF PIRSF001413 1 393 1.4E-160 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 376 1.8E-48 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 Gene3D G3DSA:3.40.50.1100 53 382 4.4E-180 T 13-10-2018 MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 7 387 1.8E-188 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 389 49.939 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 MADE_1006880 d29bafb950b44b9f74fe1292a25e0f8d 393 SUPERFAMILY SSF53686 6 387 1.44E-140 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MADE_1003360 cf73ad6a2993c2c841b81038648f178e 289 Pfam PF01476 LysM domain 49 91 1.6E-10 T 13-10-2018 IPR018392 LysM domain MADE_1003360 cf73ad6a2993c2c841b81038648f178e 289 Gene3D G3DSA:2.70.70.10 151 286 4.4E-35 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1003360 cf73ad6a2993c2c841b81038648f178e 289 Gene3D G3DSA:3.10.350.10 46 91 3.7E-12 T 13-10-2018 IPR036779 LysM domain superfamily MADE_1003360 cf73ad6a2993c2c841b81038648f178e 289 SMART SM00257 48 92 1.0E-9 T 13-10-2018 IPR018392 LysM domain MADE_1003360 cf73ad6a2993c2c841b81038648f178e 289 SUPERFAMILY SSF51261 49 285 4.03E-48 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1003360 cf73ad6a2993c2c841b81038648f178e 289 Pfam PF01551 Peptidase family M23 188 281 4.7E-28 T 13-10-2018 IPR016047 Peptidase M23 MADE_1012355 4ece993713b56cbf507d8da366520956 246 SUPERFAMILY SSF51182 144 229 3.04E-13 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1012355 4ece993713b56cbf507d8da366520956 246 Pfam PF12973 ChrR Cupin-like domain 140 220 3.0E-12 T 13-10-2018 IPR025979 ChrR-like cupin domain MADE_1012355 4ece993713b56cbf507d8da366520956 246 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 5 242 9.0E-48 T 13-10-2018 IPR012807 Anti-sigma factor ChrR, putative MADE_1012355 4ece993713b56cbf507d8da366520956 246 Gene3D G3DSA:2.60.120.10 134 225 7.9E-21 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1012355 4ece993713b56cbf507d8da366520956 246 Gene3D G3DSA:1.10.10.1320 1 133 1.9E-12 T 13-10-2018 MADE_1019290 00eebc33aa41f41503f1e1b5b834d243 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 220 6.8E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1019290 00eebc33aa41f41503f1e1b5b834d243 229 Gene3D G3DSA:1.10.3720.10 2 221 5.6E-53 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1019290 00eebc33aa41f41503f1e1b5b834d243 229 SUPERFAMILY SSF161098 4 218 1.2E-46 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1019290 00eebc33aa41f41503f1e1b5b834d243 229 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 219 6.9E-73 T 13-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MADE_1013340 ed46a349f9e2962591effeb553577d03 174 PIRSF PIRSF038996 1 172 9.6E-67 T 13-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 MADE_1013340 ed46a349f9e2962591effeb553577d03 174 Pfam PF00258 Flavodoxin 6 160 1.6E-29 T 13-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 MADE_1013340 ed46a349f9e2962591effeb553577d03 174 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MADE_1013340 ed46a349f9e2962591effeb553577d03 174 TIGRFAM TIGR01752 flav_long: flavodoxin 4 168 1.9E-70 T 13-10-2018 IPR010086 Flavodoxin, long chain GO:0010181 MADE_1013340 ed46a349f9e2962591effeb553577d03 174 SUPERFAMILY SSF52218 4 170 5.0E-52 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1013340 ed46a349f9e2962591effeb553577d03 174 Gene3D G3DSA:3.40.50.360 3 174 8.0E-55 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1010155 97fa82b32db80afb350e1ed89f2856ac 80 Pfam PF11197 Protein of unknown function (DUF2835) 11 78 5.6E-20 T 13-10-2018 IPR021363 Protein of unknown function DUF2835 MADE_1007545 6e1b8f9f10555a035db05a85c9ebc10d 360 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 354 7.2E-76 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MADE_1007545 6e1b8f9f10555a035db05a85c9ebc10d 360 Gene3D G3DSA:3.40.640.10 1 358 1.1E-87 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1007545 6e1b8f9f10555a035db05a85c9ebc10d 360 SUPERFAMILY SSF53383 13 356 6.41E-75 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1007545 6e1b8f9f10555a035db05a85c9ebc10d 360 PIRSF PIRSF000390 1 358 2.5E-84 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase MADE_1019330 40f5b012a7ab1f485d01be7a00d433e5 81 Gene3D G3DSA:3.10.20.30 1 81 4.4E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1019330 40f5b012a7ab1f485d01be7a00d433e5 81 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 81 9.9E-20 T 13-10-2018 MADE_1019330 40f5b012a7ab1f485d01be7a00d433e5 81 Pfam PF02597 ThiS family 4 81 6.6E-20 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MADE_1019330 40f5b012a7ab1f485d01be7a00d433e5 81 SUPERFAMILY SSF54285 1 81 8.41E-21 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MADE_1009800 cf50bc3e34058b2c03522c1a4f8b783d 413 Gene3D G3DSA:3.20.20.70 56 198 6.2E-7 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1009800 cf50bc3e34058b2c03522c1a4f8b783d 413 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 6 399 2.5E-162 T 13-10-2018 IPR023874 DNA modification/repair radical SAM protein, putative MADE_1009800 cf50bc3e34058b2c03522c1a4f8b783d 413 SUPERFAMILY SSF47781 305 384 6.45E-11 T 13-10-2018 IPR010994 RuvA domain 2-like MADE_1009800 cf50bc3e34058b2c03522c1a4f8b783d 413 SUPERFAMILY SSF102114 49 191 5.36E-11 T 13-10-2018 MADE_1004525 97d98a13c11b1bf2b5ecd8fc19a4537e 255 Pfam PF06629 MltA-interacting protein MipA 39 253 7.7E-39 T 13-10-2018 IPR010583 MltA-interacting MipA MADE_1015725 3f25a4dd972a635b1a63670ff2806cd8 381 Gene3D G3DSA:3.30.420.40 93 215 2.4E-34 T 13-10-2018 MADE_1015725 3f25a4dd972a635b1a63670ff2806cd8 381 Gene3D G3DSA:3.30.420.40 216 341 2.4E-34 T 13-10-2018 MADE_1015725 3f25a4dd972a635b1a63670ff2806cd8 381 SUPERFAMILY SSF46785 26 78 1.14E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1015725 3f25a4dd972a635b1a63670ff2806cd8 381 Pfam PF00480 ROK family 100 255 2.4E-19 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MADE_1015725 3f25a4dd972a635b1a63670ff2806cd8 381 SUPERFAMILY SSF53067 101 376 1.8E-29 T 13-10-2018 MADE_1015725 3f25a4dd972a635b1a63670ff2806cd8 381 Pfam PF13412 Winged helix-turn-helix DNA-binding 26 70 5.4E-8 T 13-10-2018 MADE_1015725 3f25a4dd972a635b1a63670ff2806cd8 381 Gene3D G3DSA:1.10.10.10 24 86 2.1E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015745 88cfc1e6c7f9d1ea2bbe48e45fc1b7d8 240 PIRSF PIRSF037208 1 240 7.4E-84 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 MADE_1015745 88cfc1e6c7f9d1ea2bbe48e45fc1b7d8 240 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 1 230 34.614 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 MADE_1015745 88cfc1e6c7f9d1ea2bbe48e45fc1b7d8 240 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 10 79 1.8E-18 T 13-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 MADE_1015745 88cfc1e6c7f9d1ea2bbe48e45fc1b7d8 240 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 99 223 1.5E-33 T 13-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 MADE_1015745 88cfc1e6c7f9d1ea2bbe48e45fc1b7d8 240 SUPERFAMILY SSF55729 72 232 1.94E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 SUPERFAMILY SSF48498 83 206 9.78E-34 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 Gene3D G3DSA:1.10.10.60 14 65 1.0E-19 T 13-10-2018 MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 8.9E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 4.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 4.0E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 Pfam PF08362 YcdC-like protein, C-terminal region 66 206 5.1E-47 T 13-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 Gene3D G3DSA:1.10.357.10 66 205 1.2E-43 T 13-10-2018 MADE_1007945 36023cad630253043d2bac4d38ec87a1 214 SUPERFAMILY SSF46689 13 86 3.74E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_000001023405 fcf316f37c0baf1f7fad5d36ea9ceb7b 405 Gene3D G3DSA:1.20.1250.20 187 388 3.6E-29 T 13-10-2018 MADE_000001023405 fcf316f37c0baf1f7fad5d36ea9ceb7b 405 ProSitePatterns PS00216 Sugar transport proteins signature 1. 48 64 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MADE_000001023405 fcf316f37c0baf1f7fad5d36ea9ceb7b 405 SUPERFAMILY SSF103473 2 393 8.89E-53 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_000001023405 fcf316f37c0baf1f7fad5d36ea9ceb7b 405 Gene3D G3DSA:1.20.1250.20 1 181 7.0E-32 T 13-10-2018 MADE_000001023405 fcf316f37c0baf1f7fad5d36ea9ceb7b 405 Pfam PF07690 Major Facilitator Superfamily 6 350 9.9E-40 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1014405 9ef318ebc39855b5c4785247764f4088 189 Gene3D G3DSA:1.10.520.40 12 189 1.3E-34 T 13-10-2018 IPR038287 Cse2 superfamily MADE_1014405 9ef318ebc39855b5c4785247764f4088 189 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 22 188 1.2E-29 T 13-10-2018 IPR013382 CRISPR-associated protein Cse2 MADE_1014405 9ef318ebc39855b5c4785247764f4088 189 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 40 186 3.3E-18 T 13-10-2018 IPR013382 CRISPR-associated protein Cse2 MADE_1001365 4ade7e9690a5790b0387136b5757fdb7 474 Hamap MF_00484 Glycogen synthase [glgA]. 1 472 39.704 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MADE_1001365 4ade7e9690a5790b0387136b5757fdb7 474 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 471 1.5E-157 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MADE_1001365 4ade7e9690a5790b0387136b5757fdb7 474 Gene3D G3DSA:3.40.50.2000 3 470 1.5E-163 T 13-10-2018 MADE_1001365 4ade7e9690a5790b0387136b5757fdb7 474 Pfam PF08323 Starch synthase catalytic domain 2 232 3.9E-66 T 13-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 MADE_1001365 4ade7e9690a5790b0387136b5757fdb7 474 SUPERFAMILY SSF53756 4 474 3.38E-112 T 13-10-2018 MADE_1001365 4ade7e9690a5790b0387136b5757fdb7 474 Gene3D G3DSA:3.40.50.2000 248 456 1.5E-163 T 13-10-2018 MADE_1001365 4ade7e9690a5790b0387136b5757fdb7 474 Pfam PF00534 Glycosyl transferases group 1 292 434 1.7E-13 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1012895 4f8e7a81a8f478a8081ed801e387d102 418 SUPERFAMILY SSF101960 9 412 1.44E-88 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily MADE_1012895 4f8e7a81a8f478a8081ed801e387d102 418 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 133 402 4.0E-68 T 13-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 MADE_1012895 4f8e7a81a8f478a8081ed801e387d102 418 Pfam PF01458 Uncharacterized protein family (UPF0051) 166 387 1.4E-57 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 MADE_1019720 886a287d920824c95084b3e4804a5671 251 Gene3D G3DSA:3.40.190.10 30 235 3.8E-23 T 13-10-2018 MADE_1019720 886a287d920824c95084b3e4804a5671 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 236 3.8E-20 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1019720 886a287d920824c95084b3e4804a5671 251 SUPERFAMILY SSF53850 24 236 7.25E-30 T 13-10-2018 MADE_1019720 886a287d920824c95084b3e4804a5671 251 SMART SM00062 22 240 6.8E-8 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF MADE_1019720 886a287d920824c95084b3e4804a5671 251 Gene3D G3DSA:3.40.190.10 100 201 3.8E-23 T 13-10-2018 MADE_1020505 39e835f5befedc6b068e050fd9beb240 211 Pfam PF02527 rRNA small subunit methyltransferase G 26 206 4.1E-62 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MADE_1020505 39e835f5befedc6b068e050fd9beb240 211 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 19 207 27.98 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MADE_1020505 39e835f5befedc6b068e050fd9beb240 211 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 32 210 3.4E-58 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MADE_1020505 39e835f5befedc6b068e050fd9beb240 211 SUPERFAMILY SSF53335 10 210 2.97E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1020505 39e835f5befedc6b068e050fd9beb240 211 PIRSF PIRSF003078 4 211 3.2E-61 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 MADE_1020505 39e835f5befedc6b068e050fd9beb240 211 Gene3D G3DSA:3.40.50.150 8 211 9.5E-70 T 13-10-2018 MADE_1016210 37792386b59aa13745917682c551b47e 345 Pfam PF02371 Transposase IS116/IS110/IS902 family 210 290 2.5E-13 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1016210 37792386b59aa13745917682c551b47e 345 Pfam PF01548 Transposase 7 145 9.0E-13 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1015620 400ff710225ecb831be320886dc51290 666 Gene3D G3DSA:3.40.50.2300 473 662 1.1E-23 T 13-10-2018 MADE_1015620 400ff710225ecb831be320886dc51290 666 Pfam PF04348 LppC putative lipoprotein 66 359 1.6E-27 T 13-10-2018 IPR007443 Penicillin-binding protein activator LpoA MADE_1015620 400ff710225ecb831be320886dc51290 666 Pfam PF04348 LppC putative lipoprotein 404 650 9.3E-44 T 13-10-2018 IPR007443 Penicillin-binding protein activator LpoA MADE_1015620 400ff710225ecb831be320886dc51290 666 Gene3D G3DSA:1.25.40.650 164 263 1.4E-5 T 13-10-2018 MADE_1015620 400ff710225ecb831be320886dc51290 666 SUPERFAMILY SSF53822 265 663 9.76E-57 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1013555 c800ccd50a3c8f1ab37648dfe38488fb 87 Gene3D G3DSA:3.30.2310.20 5 87 1.0E-39 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1013555 c800ccd50a3c8f1ab37648dfe38488fb 87 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 8 87 1.4E-41 T 13-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 MADE_1013555 c800ccd50a3c8f1ab37648dfe38488fb 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 8 87 3.7E-34 T 13-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 MADE_1013555 c800ccd50a3c8f1ab37648dfe38488fb 87 SUPERFAMILY SSF143011 6 86 9.55E-28 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1016355 ce4bb47793683728ec1a1b4129c76dfe 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 414 6.4E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1016355 ce4bb47793683728ec1a1b4129c76dfe 447 SUPERFAMILY SSF55874 341 436 1.44E-13 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1016355 ce4bb47793683728ec1a1b4129c76dfe 447 Pfam PF07730 Histidine kinase 242 305 4.4E-8 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MADE_1016355 ce4bb47793683728ec1a1b4129c76dfe 447 Gene3D G3DSA:3.30.565.10 310 436 5.1E-22 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1009385 5a7e20314d689db9fa16f9c8972aab9e 174 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 23 163 3.4E-48 T 13-10-2018 IPR018639 Domain of unknown function DUF2062 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 95 1.2E-50 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 Gene3D G3DSA:4.10.520.10 1 99 4.1E-38 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 Pfam PF00216 Bacterial DNA-binding protein 3 91 5.1E-32 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 SMART SM00411 3 92 3.7E-42 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 SUPERFAMILY SSF47729 3 94 5.3E-32 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 3.1E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 3.1E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 3.1E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 MADE_1008285 e207cfdd86b591eadbb89cff2c973c04 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 30.531 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 MADE_1004030 ccbe83ea4a9ad02e17bb7a089c4e59e1 245 SUPERFAMILY SSF63892 4 241 6.67E-100 T 13-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MADE_1004030 ccbe83ea4a9ad02e17bb7a089c4e59e1 245 Gene3D G3DSA:3.20.20.70 1 244 2.5E-107 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1004030 ccbe83ea4a9ad02e17bb7a089c4e59e1 245 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 243 130.231 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MADE_1004030 ccbe83ea4a9ad02e17bb7a089c4e59e1 245 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 238 2.5E-103 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MADE_1004030 ccbe83ea4a9ad02e17bb7a089c4e59e1 245 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 4.1E-97 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 MADE_1014180 b5bf8cdeca47fac3ca2da94d5fbd393a 136 Gene3D G3DSA:1.20.120.20 17 131 1.4E-6 T 13-10-2018 MADE_1014180 b5bf8cdeca47fac3ca2da94d5fbd393a 136 SUPERFAMILY SSF58113 22 133 5.62E-6 T 13-10-2018 MADE_1008495 3f74841de51cb6ad3564ca39d7cfbba6 139 SMART SM00116 13 61 2.1 T 13-10-2018 IPR000644 CBS domain MADE_1008495 3f74841de51cb6ad3564ca39d7cfbba6 139 SMART SM00116 80 128 0.0011 T 13-10-2018 IPR000644 CBS domain MADE_1008495 3f74841de51cb6ad3564ca39d7cfbba6 139 Pfam PF00571 CBS domain 73 128 8.7E-11 T 13-10-2018 IPR000644 CBS domain MADE_1008495 3f74841de51cb6ad3564ca39d7cfbba6 139 Pfam PF00571 CBS domain 6 57 1.2E-6 T 13-10-2018 IPR000644 CBS domain MADE_1008495 3f74841de51cb6ad3564ca39d7cfbba6 139 Gene3D G3DSA:3.10.580.10 1 134 2.7E-28 T 13-10-2018 MADE_1008495 3f74841de51cb6ad3564ca39d7cfbba6 139 SUPERFAMILY SSF54631 1 127 5.31E-31 T 13-10-2018 MADE_1016560 f725fc3271910c39041b103e81ed2518 173 Pfam PF01609 Transposase DDE domain 83 167 9.1E-7 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1016560 f725fc3271910c39041b103e81ed2518 173 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 2 73 6.8E-27 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family MADE_1016475 f725fc3271910c39041b103e81ed2518 173 Pfam PF01609 Transposase DDE domain 83 167 9.1E-7 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1016475 f725fc3271910c39041b103e81ed2518 173 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 2 73 6.8E-27 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 SMART SM00382 159 302 4.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 SUPERFAMILY SSF52172 7 183 6.4E-45 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 Gene3D G3DSA:1.10.8.60 310 388 2.1E-20 T 13-10-2018 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 Gene3D G3DSA:3.40.50.2300 1 130 1.7E-37 T 13-10-2018 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 Pfam PF00158 Sigma-54 interaction domain 139 305 3.3E-71 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 SUPERFAMILY SSF46689 390 440 1.43E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 Gene3D G3DSA:3.40.50.300 131 309 3.0E-64 T 13-10-2018 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 SMART SM00448 9 120 3.6E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 Gene3D G3DSA:1.10.10.60 389 442 2.7E-12 T 13-10-2018 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 Pfam PF00072 Response regulator receiver domain 12 120 1.4E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001021140 371bfce32f850471fd43742bb6cbbfbb 446 SUPERFAMILY SSF52540 138 383 3.06E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008120 c1464e3187bdab1aa3bc0c226fe628d9 738 Gene3D G3DSA:3.40.50.300 465 736 3.1E-68 T 13-10-2018 MADE_1008120 c1464e3187bdab1aa3bc0c226fe628d9 738 SUPERFAMILY SSF52540 542 729 1.1E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008120 c1464e3187bdab1aa3bc0c226fe628d9 738 Pfam PF13614 AAA domain 553 694 4.1E-11 T 13-10-2018 IPR025669 AAA domain MADE_1008120 c1464e3187bdab1aa3bc0c226fe628d9 738 Pfam PF02706 Chain length determinant protein 17 108 2.1E-12 T 13-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 MADE_1008120 c1464e3187bdab1aa3bc0c226fe628d9 738 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 522 719 9.6E-45 T 13-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 MADE_1008120 c1464e3187bdab1aa3bc0c226fe628d9 738 Pfam PF13807 G-rich domain on putative tyrosine kinase 399 470 1.2E-9 T 13-10-2018 IPR032807 Tyrosine kinase, G-rich domain MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 90 105 - T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 TIGRFAM TIGR00835 agcS: amino acid carrier protein 20 439 2.2E-140 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 Pfam PF01235 Sodium:alanine symporter family 53 448 2.4E-147 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 PRINTS PR00175 Sodium/alanine symporter signature 181 199 1.4E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 PRINTS PR00175 Sodium/alanine symporter signature 209 228 1.4E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 PRINTS PR00175 Sodium/alanine symporter signature 90 112 1.4E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 PRINTS PR00175 Sodium/alanine symporter signature 302 320 1.4E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 PRINTS PR00175 Sodium/alanine symporter signature 347 369 1.4E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1007220 de638b76c5edcb874b5d794589ef71ac 468 PRINTS PR00175 Sodium/alanine symporter signature 408 428 1.4E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1010255 1c62c208d4169cd4bdd418fa7561663e 205 SUPERFAMILY SSF161111 13 194 3.4E-34 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1010255 1c62c208d4169cd4bdd418fa7561663e 205 Pfam PF01545 Cation efflux family 23 190 7.9E-14 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 MADE_1010255 1c62c208d4169cd4bdd418fa7561663e 205 Gene3D G3DSA:1.20.1510.10 15 195 5.4E-11 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily MADE_1016325 24255a3d1f095f10fbe139b9606f7c63 401 SUPERFAMILY SSF55920 149 393 9.68E-68 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like MADE_1016325 24255a3d1f095f10fbe139b9606f7c63 401 Pfam PF01321 Creatinase/Prolidase N-terminal domain 35 170 5.9E-15 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 MADE_1016325 24255a3d1f095f10fbe139b9606f7c63 401 SUPERFAMILY SSF53092 17 169 1.4E-21 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MADE_1016325 24255a3d1f095f10fbe139b9606f7c63 401 Gene3D G3DSA:3.40.350.10 1 169 7.4E-41 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MADE_1016325 24255a3d1f095f10fbe139b9606f7c63 401 Gene3D G3DSA:3.90.230.10 170 400 2.8E-72 T 13-10-2018 MADE_1016325 24255a3d1f095f10fbe139b9606f7c63 401 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 331 343 - T 13-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MADE_1016325 24255a3d1f095f10fbe139b9606f7c63 401 Pfam PF00557 Metallopeptidase family M24 179 385 4.1E-55 T 13-10-2018 IPR000994 Peptidase M24 MADE_1008370 b8005accc3f20a0a43350a627487f3ec 130 Pfam PF02657 Fe-S metabolism associated domain 13 129 1.7E-29 T 13-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like MADE_1008370 b8005accc3f20a0a43350a627487f3ec 130 Gene3D G3DSA:3.90.1010.10 2 130 3.8E-28 T 13-10-2018 MADE_1008370 b8005accc3f20a0a43350a627487f3ec 130 SUPERFAMILY SSF82649 10 129 3.61E-25 T 13-10-2018 MADE_1005995 c74cf1a69ae1ffe17d86624b5ae43974 251 Pfam PF04344 Chemotaxis phosphatase, CheZ 43 251 1.7E-75 T 13-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 MADE_1005995 c74cf1a69ae1ffe17d86624b5ae43974 251 Gene3D G3DSA:1.10.287.500 62 196 1.1E-42 T 13-10-2018 MADE_1005995 c74cf1a69ae1ffe17d86624b5ae43974 251 PIRSF PIRSF002884 20 251 2.7E-80 T 13-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 MADE_1005995 c74cf1a69ae1ffe17d86624b5ae43974 251 SUPERFAMILY SSF75708 43 250 1.12E-63 T 13-10-2018 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 SUPERFAMILY SSF46934 1 55 1.36E-18 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 Gene3D G3DSA:1.10.286.20 192 231 1.1E-22 T 13-10-2018 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 Hamap MF_00050 Elongation factor Ts [tsf]. 1 285 81.049 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 SUPERFAMILY SSF54713 147 286 1.31E-53 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 Gene3D G3DSA:3.30.479.20 56 146 5.6E-25 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 SUPERFAMILY SSF54713 55 144 4.36E-20 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 Gene3D G3DSA:1.10.8.10 1 55 1.7E-25 T 13-10-2018 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 Pfam PF00889 Elongation factor TS 70 268 4.0E-66 T 13-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1005320 c49aae0454523ac91b89f396ca3ad257 290 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 286 7.2E-113 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 Pfam PF01259 SAICAR synthetase 7 232 1.1E-64 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 Gene3D G3DSA:3.30.200.20 7 232 2.1E-91 T 13-10-2018 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 Gene3D G3DSA:3.30.470.20 85 221 2.1E-91 T 13-10-2018 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 31.044 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 234 2.9E-78 T 13-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 MADE_1010810 8474b6c76eb6bdb843039ba5b507335a 237 SUPERFAMILY SSF56104 3 233 7.52E-80 T 13-10-2018 MADE_1009395 c955b68320a1eebe1a949a6293bb1631 900 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 404 854 1.2E-73 T 13-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 MADE_1009395 c955b68320a1eebe1a949a6293bb1631 900 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 405 536 1.1E-17 T 13-10-2018 IPR004477 ComEC/Rec2-related protein MADE_1009395 c955b68320a1eebe1a949a6293bb1631 900 SUPERFAMILY SSF56281 637 886 1.65E-34 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1009395 c955b68320a1eebe1a949a6293bb1631 900 Pfam PF00753 Metallo-beta-lactamase superfamily 647 819 1.3E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1009395 c955b68320a1eebe1a949a6293bb1631 900 SMART SM00849 649 808 0.0036 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1009395 c955b68320a1eebe1a949a6293bb1631 900 Pfam PF03772 Competence protein 296 608 1.6E-40 T 13-10-2018 IPR004477 ComEC/Rec2-related protein MADE_1009395 c955b68320a1eebe1a949a6293bb1631 900 Gene3D G3DSA:3.60.15.10 638 877 4.0E-41 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1008650 6c16926b15d121c14c24b0395da67a48 364 Gene3D G3DSA:3.90.1200.10 147 290 4.7E-7 T 13-10-2018 MADE_1008650 6c16926b15d121c14c24b0395da67a48 364 Pfam PF02958 Ecdysteroid kinase 106 178 5.0E-7 T 13-10-2018 IPR004119 Protein of unknown function DUF227 MADE_1008650 6c16926b15d121c14c24b0395da67a48 364 Pfam PF02958 Ecdysteroid kinase 209 297 2.1E-9 T 13-10-2018 IPR004119 Protein of unknown function DUF227 MADE_1008650 6c16926b15d121c14c24b0395da67a48 364 SUPERFAMILY SSF56112 67 300 4.24E-23 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1008650 6c16926b15d121c14c24b0395da67a48 364 SMART SM00587 135 298 0.0064 T 13-10-2018 IPR015897 CHK kinase-like MADE_1013865 eb6983ba542b48e23c3e9a715d6f18a8 262 Gene3D G3DSA:3.40.50.150 19 165 9.1E-10 T 13-10-2018 MADE_1013865 eb6983ba542b48e23c3e9a715d6f18a8 262 Pfam PF13489 Methyltransferase domain 35 116 1.2E-7 T 13-10-2018 MADE_1013865 eb6983ba542b48e23c3e9a715d6f18a8 262 SUPERFAMILY SSF53335 23 185 2.86E-11 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1012140 345106338df802ed40155a5c79210732 486 SUPERFAMILY SSF52151 144 468 1.78E-49 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MADE_1012140 345106338df802ed40155a5c79210732 486 Gene3D G3DSA:3.40.1090.10 222 364 5.3E-13 T 13-10-2018 MADE_1012140 345106338df802ed40155a5c79210732 486 Pfam PF11815 Domain of unknown function (DUF3336) 7 141 1.9E-33 T 13-10-2018 IPR021771 Triacylglycerol lipase GO:0004806|GO:0006629 MADE_1012140 345106338df802ed40155a5c79210732 486 Pfam PF01734 Patatin-like phospholipase 148 330 1.2E-25 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MADE_1012140 345106338df802ed40155a5c79210732 486 Gene3D G3DSA:3.40.1090.20 146 213 6.4E-8 T 13-10-2018 MADE_1003550 f5639b5c2908fcd83673168c75dd50de 208 Pfam PF00293 NUDIX domain 54 175 5.5E-12 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MADE_1003550 f5639b5c2908fcd83673168c75dd50de 208 ProSitePatterns PS00893 Nudix box signature. 94 115 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 MADE_1003550 f5639b5c2908fcd83673168c75dd50de 208 Gene3D G3DSA:3.90.79.10 2 206 2.3E-60 T 13-10-2018 MADE_1003550 f5639b5c2908fcd83673168c75dd50de 208 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 11 194 9.6E-60 T 13-10-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 MADE_1003550 f5639b5c2908fcd83673168c75dd50de 208 SUPERFAMILY SSF55811 9 203 3.82E-43 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_1010180 6fb9d5e9ab4cff1d5452284b7b84ec61 77 SUPERFAMILY SSF52833 1 77 5.26E-12 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1010180 6fb9d5e9ab4cff1d5452284b7b84ec61 77 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 77 5.3E-12 T 13-10-2018 IPR008554 Glutaredoxin-like MADE_1010180 6fb9d5e9ab4cff1d5452284b7b84ec61 77 Gene3D G3DSA:3.40.30.10 1 77 7.8E-17 T 13-10-2018 MADE_1013570 f3272679d417ec4e9640b6c4166d2866 410 SUPERFAMILY SSF53383 8 408 4.84E-102 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1013570 f3272679d417ec4e9640b6c4166d2866 410 Pfam PF00155 Aminotransferase class I and II 35 402 1.4E-60 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1013570 f3272679d417ec4e9640b6c4166d2866 410 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 166 190 1.2E-11 T 13-10-2018 MADE_1013570 f3272679d417ec4e9640b6c4166d2866 410 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 97 117 1.2E-11 T 13-10-2018 MADE_1013570 f3272679d417ec4e9640b6c4166d2866 410 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 246 270 1.2E-11 T 13-10-2018 MADE_1013570 f3272679d417ec4e9640b6c4166d2866 410 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 252 265 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 MADE_1013570 f3272679d417ec4e9640b6c4166d2866 410 Gene3D G3DSA:3.40.640.10 7 409 9.8E-115 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1001270 eeca94f7755b5eb8b0bddf25b6e78f18 153 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 2.2E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001270 eeca94f7755b5eb8b0bddf25b6e78f18 153 SUPERFAMILY SSF54523 6 131 3.53E-9 T 13-10-2018 MADE_1001270 eeca94f7755b5eb8b0bddf25b6e78f18 153 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 3.3E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001270 eeca94f7755b5eb8b0bddf25b6e78f18 153 Gene3D G3DSA:3.30.700.10 6 145 2.3E-9 T 13-10-2018 MADE_1015450 593ee4c026b23dc5cd500ad391af8db2 319 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 13-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MADE_1015450 593ee4c026b23dc5cd500ad391af8db2 319 Gene3D G3DSA:3.20.20.70 2 317 2.6E-143 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1015450 593ee4c026b23dc5cd500ad391af8db2 319 TIGRFAM TIGR00874 talAB: transaldolase 3 317 2.4E-156 T 13-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MADE_1015450 593ee4c026b23dc5cd500ad391af8db2 319 SUPERFAMILY SSF51569 1 317 4.19E-119 T 13-10-2018 MADE_1015450 593ee4c026b23dc5cd500ad391af8db2 319 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 14 312 5.7E-106 T 13-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MADE_1015450 593ee4c026b23dc5cd500ad391af8db2 319 Hamap MF_00492 Transaldolase [tal]. 2 317 51.741 T 13-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MADE_1015450 593ee4c026b23dc5cd500ad391af8db2 319 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 13-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 Pfam PF07729 FCD domain 96 223 2.3E-20 T 13-10-2018 IPR011711 GntR, C-terminal MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 SUPERFAMILY SSF46785 4 74 1.2E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 SUPERFAMILY SSF48008 92 230 5.75E-22 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 Gene3D G3DSA:1.20.120.530 94 231 2.7E-26 T 13-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.4E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.4E-9 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 SMART SM00895 96 224 6.2E-18 T 13-10-2018 IPR011711 GntR, C-terminal MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 SMART SM00345 12 71 3.8E-23 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.0E-22 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1014985 4863863b2678dde9ca4d56f5825ad922 248 Gene3D G3DSA:1.10.10.10 1 71 4.7E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016375 b9984c53eb85e8da6c2944cdcd0fc3a7 676 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 495 4.2E-182 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MADE_1016375 b9984c53eb85e8da6c2944cdcd0fc3a7 676 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 52 495 1.9E-148 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 ProSitePatterns PS00145 Urease active site. 317 333 - T 13-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 567 3.0E-293 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 ProSitePatterns PS01120 Urease nickel ligands signature. 127 140 - T 13-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 Gene3D G3DSA:3.20.20.140 129 567 7.2E-298 T 13-10-2018 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 119 3.5E-54 T 13-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 SUPERFAMILY SSF51338 422 477 7.77E-7 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 Gene3D G3DSA:2.30.40.10 4 480 7.2E-298 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 SUPERFAMILY SSF51556 129 567 1.29E-200 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 SUPERFAMILY SSF51338 2 176 1.9E-61 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 5.3E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 5.3E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 334 350 5.3E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 295 312 5.3E-34 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 Pfam PF01979 Amidohydrolase family 125 454 8.6E-82 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_1014280 0ce8d3fb968e9a803141835d1cb91d97 567 Hamap MF_01953 Urease subunit alpha [ureC]. 2 567 56.928 T 13-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 SUPERFAMILY SSF158682 21 235 4.97E-28 T 13-10-2018 IPR029024 TerB-like MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 Pfam PF05099 Tellurite resistance protein TerB 52 176 4.1E-15 T 13-10-2018 IPR007791 Co-chaperone DjlA, N-terminal MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 PRINTS PR00625 DnaJ domain signature 267 287 3.5E-8 T 13-10-2018 IPR001623 DnaJ domain MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 PRINTS PR00625 DnaJ domain signature 225 243 3.5E-8 T 13-10-2018 IPR001623 DnaJ domain MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 PRINTS PR00625 DnaJ domain signature 243 258 3.5E-8 T 13-10-2018 IPR001623 DnaJ domain MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 Hamap MF_01153 Co-chaperone protein DjlA [djlA]. 3 288 37.683 T 13-10-2018 IPR023749 Co-chaperone DjlA GO:0051087 MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 Gene3D G3DSA:1.10.3680.10 46 195 3.1E-25 T 13-10-2018 IPR029024 TerB-like MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 SMART SM00271 222 287 3.0E-13 T 13-10-2018 IPR001623 DnaJ domain MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 SUPERFAMILY SSF46565 218 284 1.64E-15 T 13-10-2018 IPR036869 Chaperone J-domain superfamily MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 Pfam PF00226 DnaJ domain 223 284 3.7E-11 T 13-10-2018 IPR001623 DnaJ domain MADE_1004000 00a24bd80a7a6c448c4674ae97d690fd 288 Gene3D G3DSA:1.10.287.110 198 287 2.5E-15 T 13-10-2018 IPR036869 Chaperone J-domain superfamily MADE_1006590 00fcc168920df4ec617c3fcbd230e5b5 201 Gene3D G3DSA:3.40.30.10 1 198 1.0E-72 T 13-10-2018 MADE_1006590 00fcc168920df4ec617c3fcbd230e5b5 201 PIRSF PIRSF000239 1 200 1.6E-57 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1006590 00fcc168920df4ec617c3fcbd230e5b5 201 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 161 195 1.5E-9 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1006590 00fcc168920df4ec617c3fcbd230e5b5 201 SUPERFAMILY SSF52833 3 195 3.56E-66 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1006590 00fcc168920df4ec617c3fcbd230e5b5 201 Pfam PF00578 AhpC/TSA family 5 140 7.0E-33 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Pfam PF16355 Domain of unknown function (DUF4982) 592 658 1.2E-8 T 13-10-2018 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 SUPERFAMILY SSF49785 6 166 4.25E-39 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Pfam PF00703 Glycosyl hydrolases family 2 184 287 1.7E-18 T 13-10-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 61 164 4.2E-20 T 13-10-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 PRINTS PR00132 Glycosyl hydrolase family 2 signature 90 105 6.6E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 PRINTS PR00132 Glycosyl hydrolase family 2 signature 299 313 6.6E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 PRINTS PR00132 Glycosyl hydrolase family 2 signature 395 410 6.6E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 PRINTS PR00132 Glycosyl hydrolase family 2 signature 330 348 6.6E-11 T 13-10-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-2206292|Reactome: R-HSA-6798695 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 SUPERFAMILY SSF51445 284 565 2.28E-47 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Gene3D G3DSA:2.60.120.260 14 166 1.1E-40 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 SUPERFAMILY SSF49303 179 286 2.27E-19 T 13-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Gene3D G3DSA:3.20.20.80 290 569 1.9E-47 T 13-10-2018 MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Gene3D G3DSA:2.60.40.10 581 664 3.8E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Gene3D G3DSA:2.60.40.10 172 287 7.4E-25 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1001170 542212a51a8c27b5847a08fabf7e5335 763 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 294 425 2.2E-19 T 13-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 MADE_1016730 ae36ca12cc5a15e6e7c497bf91030830 248 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 33 243 2.0E-83 T 13-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MADE_1016730 ae36ca12cc5a15e6e7c497bf91030830 248 Gene3D G3DSA:3.40.50.620 6 216 1.1E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1016730 ae36ca12cc5a15e6e7c497bf91030830 248 SUPERFAMILY SSF52402 23 208 7.41E-54 T 13-10-2018 MADE_1016730 ae36ca12cc5a15e6e7c497bf91030830 248 PIRSF PIRSF000857 1 246 6.0E-58 T 13-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MADE_1016730 ae36ca12cc5a15e6e7c497bf91030830 248 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 21 242 1.3E-86 T 13-10-2018 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8 MADE_1016730 ae36ca12cc5a15e6e7c497bf91030830 248 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 13 243 38.353 T 13-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 MADE_1016730 ae36ca12cc5a15e6e7c497bf91030830 248 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 48 219 3.4E-50 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MADE_1010160 f3fbf6166d461f8d8e7dace9ef761a6a 686 Pfam PF06980 Protein of unknown function (DUF1302) 33 685 2.1E-183 T 13-10-2018 IPR010727 Protein of unknown function DUF1302 MADE_1016115 b78caf75a5a93b1d288ed67493f27c50 97 Gene3D G3DSA:3.30.2310.20 1 93 3.7E-24 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1016115 b78caf75a5a93b1d288ed67493f27c50 97 PIRSF PIRSF029218 1 97 4.7E-31 T 13-10-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 MADE_1016115 b78caf75a5a93b1d288ed67493f27c50 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 91 9.0E-14 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_000001022790 fd815bf5eebb5f3386fd7be0578432b4 253 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 1 253 47.13 T 13-10-2018 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 MADE_000001022790 fd815bf5eebb5f3386fd7be0578432b4 253 Gene3D G3DSA:3.40.50.150 1 248 6.1E-60 T 13-10-2018 MADE_000001022790 fd815bf5eebb5f3386fd7be0578432b4 253 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 106 112 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_000001022790 fd815bf5eebb5f3386fd7be0578432b4 253 SUPERFAMILY SSF53335 25 189 4.88E-24 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_000001022790 fd815bf5eebb5f3386fd7be0578432b4 253 Pfam PF05175 Methyltransferase small domain 25 121 1.7E-13 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MADE_1002575 e5e1fbbe1f5c899249aee0f427bbec16 175 Gene3D G3DSA:2.30.30.830 77 169 3.6E-23 T 13-10-2018 MADE_1002575 e5e1fbbe1f5c899249aee0f427bbec16 175 Pfam PF04351 Pilus assembly protein, PilP 23 167 2.9E-44 T 13-10-2018 IPR007446 Pilus assembly protein PilP MADE_1002575 e5e1fbbe1f5c899249aee0f427bbec16 175 PIRSF PIRSF016481 2 173 3.9E-36 T 13-10-2018 IPR007446 Pilus assembly protein PilP MADE_1007550 e6cc4952d3895d8a6c6e5103106ae954 345 SUPERFAMILY SSF50891 96 302 6.87E-35 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1007550 e6cc4952d3895d8a6c6e5103106ae954 345 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 97 285 2.4E-34 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 MADE_1007550 e6cc4952d3895d8a6c6e5103106ae954 345 Gene3D G3DSA:2.40.100.10 39 293 8.7E-38 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1003890 d5d017220f0bf6fa72d44a20c1ea025f 135 Gene3D G3DSA:3.30.420.270 62 130 1.9E-10 T 13-10-2018 MADE_1003890 d5d017220f0bf6fa72d44a20c1ea025f 135 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 133 2.2E-33 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MADE_1006325 88abb54117acad494099114529b79c7d 98 Gene3D G3DSA:2.60.120.620 1 98 1.0E-5 T 13-10-2018 MADE_1016545 1ef337a5baa2555fdbefb6e0965dfc79 232 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 30 225 2.8E-51 T 13-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016545 1ef337a5baa2555fdbefb6e0965dfc79 232 SUPERFAMILY SSF49503 114 228 2.54E-45 T 13-10-2018 IPR008972 Cupredoxin MADE_1016545 1ef337a5baa2555fdbefb6e0965dfc79 232 Gene3D G3DSA:2.60.40.2600 113 232 2.2E-48 T 13-10-2018 MADE_1016545 1ef337a5baa2555fdbefb6e0965dfc79 232 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 161 209 - T 13-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016545 1ef337a5baa2555fdbefb6e0965dfc79 232 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 138 213 3.1E-18 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1014920 09a0df91dd37c43b0fdbb85a30b19162 248 Pfam PF04338 Protein of unknown function, DUF481 33 247 2.1E-58 T 13-10-2018 IPR007433 Protein of unknown function DUF481 MADE_1012420 c18cb21120bf818787a439b3a291ff94 166 Pfam PF04608 Phosphatidylglycerophosphatase A 16 155 3.5E-49 T 13-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 MADE_1012420 c18cb21120bf818787a439b3a291ff94 166 SUPERFAMILY SSF101307 9 156 4.45E-42 T 13-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 MADE_1012420 c18cb21120bf818787a439b3a291ff94 166 PIRSF PIRSF006162 6 163 8.7E-52 T 13-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MADE_1011535 85e1d853770e90946648b62b162ca01b 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.9E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011535 85e1d853770e90946648b62b162ca01b 307 Gene3D G3DSA:1.10.10.10 2 85 3.4E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1011535 85e1d853770e90946648b62b162ca01b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 7.0E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011535 85e1d853770e90946648b62b162ca01b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 7.0E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011535 85e1d853770e90946648b62b162ca01b 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 7.0E-5 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1011535 85e1d853770e90946648b62b162ca01b 307 Pfam PF03466 LysR substrate binding domain 90 289 1.4E-28 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1011535 85e1d853770e90946648b62b162ca01b 307 SUPERFAMILY SSF46785 5 89 5.01E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1011535 85e1d853770e90946648b62b162ca01b 307 SUPERFAMILY SSF53850 87 290 4.71E-31 T 13-10-2018 MADE_1011535 85e1d853770e90946648b62b162ca01b 307 Gene3D G3DSA:3.40.190.290 95 288 1.0E-24 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 336 2.3E-62 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PIRSF PIRSF000350 2 479 2.7E-223 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PRINTS PR00945 Mercuric reductase class II signature 155 172 3.9E-66 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PRINTS PR00945 Mercuric reductase class II signature 452 471 3.9E-66 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PRINTS PR00945 Mercuric reductase class II signature 28 46 3.9E-66 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PRINTS PR00945 Mercuric reductase class II signature 64 83 3.9E-66 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PRINTS PR00945 Mercuric reductase class II signature 190 207 3.9E-66 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PRINTS PR00945 Mercuric reductase class II signature 387 407 3.9E-66 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 PRINTS PR00945 Mercuric reductase class II signature 210 225 3.9E-66 T 13-10-2018 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 Gene3D G3DSA:3.50.50.60 163 279 2.6E-102 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 52 62 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 Gene3D G3DSA:3.30.390.30 354 479 6.3E-44 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 TIGRFAM TIGR02053 MerA: mercury(II) reductase 18 479 4.7E-163 T 13-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 355 461 3.2E-29 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 SUPERFAMILY SSF51905 16 374 3.24E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 Gene3D G3DSA:3.50.50.60 20 337 2.6E-102 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1010355 702bca2eae7f33078de2464b7d37de24 479 SUPERFAMILY SSF55424 354 476 7.73E-34 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 MADE_1002015 a6881a32e1eb01350f36fa035a6ba962 205 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 17 175 27.832 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MADE_1002015 a6881a32e1eb01350f36fa035a6ba962 205 Pfam PF03975 CheD chemotactic sensory transduction 64 171 2.5E-28 T 13-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 MADE_1002015 a6881a32e1eb01350f36fa035a6ba962 205 SUPERFAMILY SSF64438 22 175 7.05E-48 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MADE_1002015 a6881a32e1eb01350f36fa035a6ba962 205 Gene3D G3DSA:3.30.1330.200 20 182 1.3E-49 T 13-10-2018 IPR038592 CheD-like superfamily MADE_1008025 0f9c005bc3d98b5e1e378116c93a682b 272 Pfam PF01925 Sulfite exporter TauE/SafE 15 266 3.2E-47 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MADE_1008115 74b82fedec16ddf419b45b3512a272a4 153 Pfam PF10531 SLBB domain 81 124 1.9E-9 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 MADE_1008115 74b82fedec16ddf419b45b3512a272a4 153 Pfam PF02563 Polysaccharide biosynthesis/export protein 2 74 1.2E-17 T 13-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MADE_1008115 74b82fedec16ddf419b45b3512a272a4 153 Gene3D G3DSA:3.30.1950.10 7 78 5.0E-19 T 13-10-2018 MADE_1008115 74b82fedec16ddf419b45b3512a272a4 153 Gene3D G3DSA:3.10.560.10 2 150 5.0E-19 T 13-10-2018 MADE_1002040 06f71ad0a864bb86287a14353e375f76 282 Pfam PF08388 Group II intron, maturase-specific domain 152 226 1.1E-17 T 13-10-2018 IPR013597 Group II intron, maturase-specific MADE_1002040 06f71ad0a864bb86287a14353e375f76 282 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 1 139 7.4E-27 T 13-10-2018 IPR000477 Reverse transcriptase domain MADE_1002040 06f71ad0a864bb86287a14353e375f76 282 SUPERFAMILY SSF56672 1 226 4.6E-30 T 13-10-2018 MADE_1008270 2ed62f88f4902cdbce724b03cc02bb26 277 SUPERFAMILY SSF53335 46 258 4.06E-21 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1008270 2ed62f88f4902cdbce724b03cc02bb26 277 Pfam PF08241 Methyltransferase domain 91 183 4.7E-10 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MADE_1008270 2ed62f88f4902cdbce724b03cc02bb26 277 Gene3D G3DSA:3.40.50.150 32 259 7.9E-23 T 13-10-2018 MADE_1000480 4da5d02e8dc1fa53097120e1eed8ee7d 147 Gene3D G3DSA:3.40.1260.10 19 146 2.2E-8 T 13-10-2018 IPR027396 DsrEFH-like MADE_1000480 4da5d02e8dc1fa53097120e1eed8ee7d 147 SUPERFAMILY SSF75169 31 146 4.36E-14 T 13-10-2018 IPR027396 DsrEFH-like MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 Pfam PF03934 Type II secretion system (T2SS), protein K 57 347 1.1E-82 T 13-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 Gene3D G3DSA:1.10.40.60 126 249 9.2E-81 T 13-10-2018 IPR038072 GspK, central domain superfamily MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 Gene3D G3DSA:1.10.40.60 250 316 9.2E-81 T 13-10-2018 IPR038072 GspK, central domain superfamily MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 PIRSF PIRSF002786 27 357 6.6E-71 T 13-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 Gene3D G3DSA:3.30.1300.30 69 339 9.2E-81 T 13-10-2018 MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 SUPERFAMILY SSF158544 249 316 1.83E-13 T 13-10-2018 IPR038072 GspK, central domain superfamily MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 SUPERFAMILY SSF158544 128 245 6.02E-29 T 13-10-2018 IPR038072 GspK, central domain superfamily MADE_1019860 31fc8b7b3d557990b232a286eea8f48f 358 SUPERFAMILY SSF54523 63 356 1.02E-27 T 13-10-2018 MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 SUPERFAMILY SSF46894 130 227 1.05E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 Pfam PF00072 Response regulator receiver domain 5 116 8.4E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 SUPERFAMILY SSF52172 2 134 1.71E-29 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 SMART SM00862 154 227 8.8E-14 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 SMART SM00448 3 116 1.2E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 Gene3D G3DSA:3.40.50.2300 1 124 2.5E-27 T 13-10-2018 MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 TIGRFAM TIGR03787 marine_sort_RR: proteobacterial dedicated sortase system response regulator 3 228 5.7E-120 T 13-10-2018 IPR022305 Sortase system response regulator MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 Gene3D G3DSA:1.10.10.10 140 229 6.5E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1018475 be6fd7cac090f8f705cb770542e3ed8b 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 226 1.4E-14 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1019055 f3e4fd6b9dc120897723a1562e4c42b6 555 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1019055 f3e4fd6b9dc120897723a1562e4c42b6 555 SUPERFAMILY SSF52540 359 546 2.71E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019055 f3e4fd6b9dc120897723a1562e4c42b6 555 Gene3D G3DSA:3.40.50.300 340 553 3.7E-39 T 13-10-2018 MADE_1019055 f3e4fd6b9dc120897723a1562e4c42b6 555 Pfam PF00005 ABC transporter 360 496 4.1E-18 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1019055 f3e4fd6b9dc120897723a1562e4c42b6 555 SMART SM00382 367 543 2.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1009295 4141a5b8faadd0770da7df820953fd09 163 SUPERFAMILY SSF48295 2 52 2.98E-10 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MADE_1009295 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 56 133 1.9E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1009295 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 2 48 1.2E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1009285 4141a5b8faadd0770da7df820953fd09 163 SUPERFAMILY SSF48295 2 52 2.98E-10 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MADE_1009285 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 56 133 1.9E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1009285 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 2 48 1.2E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1007380 4141a5b8faadd0770da7df820953fd09 163 SUPERFAMILY SSF48295 2 52 2.98E-10 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MADE_1007380 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 56 133 1.9E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1007380 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 2 48 1.2E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1007035 4141a5b8faadd0770da7df820953fd09 163 SUPERFAMILY SSF48295 2 52 2.98E-10 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 MADE_1007035 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 56 133 1.9E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1007035 4141a5b8faadd0770da7df820953fd09 163 Pfam PF01527 Transposase 2 48 1.2E-7 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1020290 6944def2abb63bdbf1cd14ded493cb64 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 287 2.8E-35 T 13-10-2018 IPR013551 Domain of unknown function DUF1732 MADE_1020290 6944def2abb63bdbf1cd14ded493cb64 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 5.2E-44 T 13-10-2018 IPR013527 YicC-like, N-terminal MADE_1020290 6944def2abb63bdbf1cd14ded493cb64 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 287 1.7E-119 T 13-10-2018 IPR005229 Conserved hypothetical protein CHP00255 MADE_1007200 5c31ea16553aa6465ffd44fa028a7859 853 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 178 4.9E-21 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1007200 5c31ea16553aa6465ffd44fa028a7859 853 Gene3D G3DSA:2.170.130.10 37 182 3.0E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1007200 5c31ea16553aa6465ffd44fa028a7859 853 SUPERFAMILY SSF56935 41 853 5.49E-99 T 13-10-2018 MADE_1007200 5c31ea16553aa6465ffd44fa028a7859 853 Gene3D G3DSA:2.40.170.20 358 853 2.8E-56 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1007200 5c31ea16553aa6465ffd44fa028a7859 853 Pfam PF00593 TonB dependent receptor 330 852 4.1E-36 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 Pfam PF02119 Flagellar P-ring protein 23 369 9.3E-134 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 38 53 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 120 138 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 161 179 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 81 100 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 23 38 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 187 205 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 55 70 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 PRINTS PR01010 Flagellar P-ring protein signature 103 120 1.3E-74 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1005740 0952eebb04eb14f90a34807b59abbdc9 370 Hamap MF_00416 Flagellar P-ring protein [flgI]. 2 370 38.402 T 13-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 SMART SM00849 14 238 1.4E-18 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 402 463 3.5E-16 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 SUPERFAMILY SSF56281 3 469 4.19E-121 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 SMART SM01027 254 388 6.9E-46 T 13-10-2018 IPR022712 Beta-Casp domain MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 Gene3D G3DSA:3.60.15.10 7 448 1.6E-141 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 Pfam PF10996 Beta-Casp domain 254 387 1.8E-26 T 13-10-2018 IPR022712 Beta-Casp domain MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 Gene3D G3DSA:3.40.50.10890 222 414 1.6E-141 T 13-10-2018 MADE_1016315 c9608c6b2127525dc1bc41a6a463130e 471 Pfam PF16661 Metallo-beta-lactamase superfamily domain 19 200 3.4E-14 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 SUPERFAMILY SSF50447 240 327 1.88E-24 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 Pfam PF00009 Elongation factor Tu GTP binding domain 23 228 4.3E-45 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 Gene3D G3DSA:2.40.30.10 237 326 1.5E-27 T 13-10-2018 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 Gene3D G3DSA:3.40.50.300 1 236 9.9E-76 T 13-10-2018 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 25 430 3.1E-198 T 13-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 PRINTS PR00315 GTP-binding elongation factor signature 87 95 1.9E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 PRINTS PR00315 GTP-binding elongation factor signature 123 134 1.9E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 PRINTS PR00315 GTP-binding elongation factor signature 26 39 1.9E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 PRINTS PR00315 GTP-binding elongation factor signature 160 169 1.9E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 PRINTS PR00315 GTP-binding elongation factor signature 107 117 1.9E-13 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 Gene3D G3DSA:2.40.30.10 327 432 2.9E-35 T 13-10-2018 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 31 210 1.3E-13 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 80 95 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 16 470 53.131 T 13-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 SUPERFAMILY SSF52540 17 233 8.65E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006725 530d11dfe277daf3ed4733fba2d7e3c7 471 SUPERFAMILY SSF50465 331 431 1.15E-33 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal MADE_1018070 cf76817ffa17a2b2be17fa042775b402 83 TIGRFAM TIGR02647 DNA: TIGR02647 family protein 3 76 2.5E-29 T 13-10-2018 IPR013468 Conserved hypothetical protein CHP02647 MADE_1018070 cf76817ffa17a2b2be17fa042775b402 83 Pfam PF06146 Phosphate-starvation-inducible E 10 69 2.2E-12 T 13-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like MADE_1002000 fe8cf64d3d1282f1d900af84c6c1619a 121 Gene3D G3DSA:3.40.50.12740 1 121 5.8E-38 T 13-10-2018 MADE_1002000 fe8cf64d3d1282f1d900af84c6c1619a 121 SMART SM00448 3 116 1.2E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1002000 fe8cf64d3d1282f1d900af84c6c1619a 121 SUPERFAMILY SSF52172 3 121 5.12E-37 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1002000 fe8cf64d3d1282f1d900af84c6c1619a 121 Pfam PF00072 Response regulator receiver domain 5 115 3.2E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1009590 64992b1aa4f2da52774241271de5b658 865 SUPERFAMILY SSF53474 477 636 1.95E-12 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1009590 64992b1aa4f2da52774241271de5b658 865 TIGRFAM TIGR03502 lipase_Pla1_cef: extracellular lipase, Pla-1/cef family 1 850 4.0E-239 T 13-10-2018 IPR020009 Extracellular lipase, Pla-1/cef family MADE_1009590 64992b1aa4f2da52774241271de5b658 865 Pfam PF12262 Bacterial virulence factor lipase N-terminal 1 275 3.3E-31 T 13-10-2018 IPR025920 Bacterial virulence factor lipase, N-terminal domain MADE_1009590 64992b1aa4f2da52774241271de5b658 865 Gene3D G3DSA:3.40.50.1820 473 656 4.9E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 SUPERFAMILY SSF46894 137 209 2.82E-18 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 Gene3D G3DSA:3.40.50.12740 2 209 7.9E-46 T 13-10-2018 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 SMART SM00421 147 204 1.1E-18 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 Pfam PF00072 Response regulator receiver domain 5 115 1.2E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 SUPERFAMILY SSF52172 1 130 2.42E-23 T 13-10-2018 IPR011006 CheY-like superfamily MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 5.2E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 5.2E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 5.2E-8 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 2.8E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 MADE_000001023130 13bccd2b8d87c9f5246220edc000eca9 214 SMART SM00448 2 115 1.8E-11 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1010440 1df0b431961e989f30942e1c96b0db8e 159 Pfam PF05751 FixH 7 146 8.0E-40 T 13-10-2018 IPR008620 Nitrogen fixation protein FixH MADE_000001021190 b3c498656a7e3ac81c393aa6f1da4ab7 132 Gene3D G3DSA:3.10.129.10 1 131 4.6E-40 T 13-10-2018 MADE_000001021190 b3c498656a7e3ac81c393aa6f1da4ab7 132 PIRSF PIRSF003230 1 132 7.5E-45 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MADE_000001021190 b3c498656a7e3ac81c393aa6f1da4ab7 132 Pfam PF03061 Thioesterase superfamily 16 99 3.4E-15 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MADE_000001021190 b3c498656a7e3ac81c393aa6f1da4ab7 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 6 120 7.6E-37 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 MADE_000001021190 b3c498656a7e3ac81c393aa6f1da4ab7 132 SUPERFAMILY SSF54637 2 125 2.24E-37 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_000001021190 b3c498656a7e3ac81c393aa6f1da4ab7 132 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 2 125 1.2E-48 T 13-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 MADE_1001380 19b44aa0d28ff46edbd077c47b93b9ef 234 SUPERFAMILY SSF53474 6 230 1.03E-31 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1001380 19b44aa0d28ff46edbd077c47b93b9ef 234 Gene3D G3DSA:3.40.50.1820 2 231 1.2E-33 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1001380 19b44aa0d28ff46edbd077c47b93b9ef 234 Pfam PF00561 alpha/beta hydrolase fold 54 219 1.4E-15 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 Gene3D G3DSA:1.20.5.100 201 228 4.1E-20 T 13-10-2018 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 Gene3D G3DSA:3.40.50.720 229 395 4.6E-67 T 13-10-2018 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 PIRSF PIRSF500134 345 395 6.9 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 PIRSF PIRSF500134 8 372 1.1E-120 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 PIRSF PIRSF000124 8 395 1.1E-134 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 9 380 1.4E-100 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 Gene3D G3DSA:3.40.50.720 7 200 1.2E-57 T 13-10-2018 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 SUPERFAMILY SSF52413 290 394 3.01E-26 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 288 8.3E-28 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 SUPERFAMILY SSF48179 198 294 1.25E-30 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 308 374 9.2E-8 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 SUPERFAMILY SSF51735 9 201 5.9E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013795 6c06e32e0955872c69393aed790323ee 395 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 9 176 1.2E-31 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MADE_1013795 6c06e32e0955872c69393aed790323ee 395 SMART SM00984 307 394 9.6E-13 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 MADE_1001330 c658dce8f2773fdf0a0c465f8dcceddf 480 PIRSF PIRSF004919 15 480 1.2E-143 T 13-10-2018 IPR025502 TldD MADE_1001330 c658dce8f2773fdf0a0c465f8dcceddf 480 Gene3D G3DSA:3.30.2290.10 15 235 1.5E-15 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal MADE_1001330 c658dce8f2773fdf0a0c465f8dcceddf 480 SUPERFAMILY SSF111283 20 479 2.09E-129 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 MADE_1001330 c658dce8f2773fdf0a0c465f8dcceddf 480 Pfam PF01523 Putative modulator of DNA gyrase 34 331 3.4E-66 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 Gene3D G3DSA:3.40.309.10 249 440 2.3E-142 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 SUPERFAMILY SSF53720 3 458 7.98E-125 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 Hamap MF_01174 N-succinylglutamate 5-semialdehyde dehydrogenase [astD]. 3 489 57.427 T 13-10-2018 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 TIGRFAM TIGR03240 arg_catab_astD: succinylglutamate-semialdehyde dehydrogenase 5 488 2.7E-249 T 13-10-2018 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 Gene3D G3DSA:3.40.605.10 9 452 2.3E-142 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1002500 ae430458e895d5c7634bb05f5c6c6448 489 Pfam PF00171 Aldehyde dehydrogenase family 11 462 1.3E-121 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 PRINTS PR00478 Phosphoribulokinase family signature 126 144 4.9E-27 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 PRINTS PR00478 Phosphoribulokinase family signature 12 29 4.9E-27 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 PRINTS PR00478 Phosphoribulokinase family signature 182 205 4.9E-27 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 PRINTS PR00478 Phosphoribulokinase family signature 164 181 4.9E-27 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 Gene3D G3DSA:3.40.50.300 1 290 1.4E-112 T 13-10-2018 MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 1.6E-69 T 13-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 SUPERFAMILY SSF52540 4 286 1.57E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019770 25d3f2bef7396e4c5d2841e12a2dbb99 301 ProSitePatterns PS00567 Phosphoribulokinase signature. 164 177 - T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 MADE_1002925 f84569e49a9da0f99ab573cd9d963420 392 SUPERFAMILY SSF53383 25 384 3.86E-35 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1002925 f84569e49a9da0f99ab573cd9d963420 392 Gene3D G3DSA:3.40.640.10 29 295 3.2E-33 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1002925 f84569e49a9da0f99ab573cd9d963420 392 Pfam PF00266 Aminotransferase class-V 55 361 4.4E-13 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_1002925 f84569e49a9da0f99ab573cd9d963420 392 Gene3D G3DSA:3.90.1150.10 296 384 3.2E-33 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 318 1.0E-30 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 Gene3D G3DSA:3.40.50.1220 180 327 2.3E-35 T 13-10-2018 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 SUPERFAMILY SSF52467 178 361 1.04E-39 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 Gene3D G3DSA:3.40.50.970 335 540 4.1E-53 T 13-10-2018 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 168 8.0E-56 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 SUPERFAMILY SSF52518 355 540 1.81E-56 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 Gene3D G3DSA:3.40.50.970 1 179 2.1E-62 T 13-10-2018 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 524 1.4E-36 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 13-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 MADE_000001023515 f63d75a2e3f48790c83332f7a10c811e 546 SUPERFAMILY SSF52518 1 177 1.4E-49 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1013695 510e75fa22bdd4cfea4e962c37f8b4bb 211 SMART SM00563 57 169 1.2E-16 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_1013695 510e75fa22bdd4cfea4e962c37f8b4bb 211 SUPERFAMILY SSF69593 24 170 7.59E-21 T 13-10-2018 MADE_1013695 510e75fa22bdd4cfea4e962c37f8b4bb 211 Pfam PF01553 Acyltransferase 45 164 3.3E-14 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 MADE_000001022625 0566b18e1ca08ed9aed26a3d66c3c742 409 Gene3D G3DSA:3.40.50.10180 30 244 1.9E-124 T 13-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 MADE_000001022625 0566b18e1ca08ed9aed26a3d66c3c742 409 Pfam PF13660 Domain of unknown function (DUF4147) 9 227 9.0E-68 T 13-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 MADE_000001022625 0566b18e1ca08ed9aed26a3d66c3c742 409 Gene3D G3DSA:3.40.1480.10 245 405 1.9E-124 T 13-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily MADE_000001022625 0566b18e1ca08ed9aed26a3d66c3c742 409 SUPERFAMILY SSF82544 4 408 6.02E-125 T 13-10-2018 MADE_000001022625 0566b18e1ca08ed9aed26a3d66c3c742 409 Pfam PF05161 MOFRL family 297 402 5.9E-33 T 13-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Pfam PF09312 SurA N-terminal domain 25 142 5.3E-39 T 13-10-2018 IPR015391 SurA N-terminal MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Gene3D G3DSA:1.10.4030.30 26 277 1.5E-70 T 13-10-2018 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Gene3D G3DSA:3.10.50.40 281 380 2.1E-34 T 13-10-2018 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Gene3D G3DSA:3.10.50.40 172 274 1.5E-70 T 13-10-2018 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 SUPERFAMILY SSF54534 173 275 3.34E-26 T 13-10-2018 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Hamap MF_01183 Chaperone SurA [surA]. 4 427 34.858 T 13-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Pfam PF00639 PPIC-type PPIASE domain 178 271 2.6E-19 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Pfam PF00639 PPIC-type PPIASE domain 288 381 1.8E-23 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 Gene3D G3DSA:1.10.4030.30 381 427 5.6E-7 T 13-10-2018 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 SUPERFAMILY SSF109998 25 201 1.1E-39 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 320 341 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 MADE_1003990 59d790d6e6a978c9b103e56fe6dac59a 427 SUPERFAMILY SSF54534 282 383 3.47E-31 T 13-10-2018 MADE_1005825 c1855f00f8d60fbc3aaeec2711d323c0 347 Pfam PF02371 Transposase IS116/IS110/IS902 family 216 293 3.6E-19 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1005825 c1855f00f8d60fbc3aaeec2711d323c0 347 Pfam PF01548 Transposase 7 149 1.5E-17 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 SUPERFAMILY SSF51735 4 150 1.78E-52 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 123 6.9E-25 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 SMART SM00859 5 125 1.4E-28 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 5 370 4.8E-190 T 13-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 Gene3D G3DSA:3.40.50.720 3 142 7.0E-59 T 13-10-2018 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 147 357 3.9E-55 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 SUPERFAMILY SSF55347 137 358 4.05E-76 T 13-10-2018 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 265 279 - T 13-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 Gene3D G3DSA:3.30.360.10 143 354 3.8E-81 T 13-10-2018 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 PIRSF PIRSF000148 3 374 1.6E-66 T 13-10-2018 MADE_000001021270 457e422dfa853f556a1b409464f9b9ad 374 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 3 371 33.184 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 MADE_1008365 edcc7f4b8cc1290cb8723e3626150f6d 131 Pfam PF11042 Protein of unknown function (DUF2750) 29 128 1.4E-18 T 13-10-2018 IPR021284 Protein of unknown function DUF2750 MADE_1003865 9312b680be2d053d631cecf25cc83204 930 SMART SM00710 339 363 5900.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1003865 9312b680be2d053d631cecf25cc83204 930 SMART SM00710 775 799 2200.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1003865 9312b680be2d053d631cecf25cc83204 930 SMART SM00710 254 276 850.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1003865 9312b680be2d053d631cecf25cc83204 930 SMART SM00710 533 554 5700.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1003865 9312b680be2d053d631cecf25cc83204 930 SMART SM00710 690 712 39.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1000875 af4df4c0ed6ca93e5580ed39c543685d 200 Pfam PF01810 LysE type translocator 15 198 7.8E-34 T 13-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 SUPERFAMILY SSF51230 585 657 7.85E-20 T 13-10-2018 IPR011053 Single hybrid motif MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 SUPERFAMILY SSF56059 83 347 6.72E-67 T 13-10-2018 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 615 632 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 Gene3D G3DSA:2.40.50.100 593 658 2.9E-20 T 13-10-2018 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 Pfam PF00364 Biotin-requiring enzyme 592 656 2.3E-14 T 13-10-2018 IPR000089 Biotin/lipoyl attachment MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 SUPERFAMILY SSF51246 331 449 4.71E-41 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 9.5E-39 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 9.4E-73 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 Gene3D G3DSA:3.30.470.130 1 451 4.9E-196 T 13-10-2018 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 SUPERFAMILY SSF52440 1 113 1.15E-48 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 SMART SM00878 336 443 2.5E-56 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1008430 e0b53dff9b2ebd6fdef79b0d5912de9b 666 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.0E-43 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 MADE_1010620 074c3fe80e1b5df29d7ed563e599bfdc 516 Gene3D G3DSA:3.40.640.10 93 189 5.9E-22 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1010620 074c3fe80e1b5df29d7ed563e599bfdc 516 Gene3D G3DSA:3.40.640.10 214 368 4.2E-40 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1010620 074c3fe80e1b5df29d7ed563e599bfdc 516 Pfam PF00155 Aminotransferase class I and II 99 506 1.7E-25 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1010620 074c3fe80e1b5df29d7ed563e599bfdc 516 Gene3D G3DSA:3.90.1150.10 369 418 4.2E-40 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1010620 074c3fe80e1b5df29d7ed563e599bfdc 516 Gene3D G3DSA:3.90.1150.10 65 92 5.9E-22 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1010620 074c3fe80e1b5df29d7ed563e599bfdc 516 SUPERFAMILY SSF53383 63 510 5.09E-56 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_000001021195 d7cb1ef4a746e69116c5eda5b6e9c4a5 229 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 5 223 43.694 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 MADE_000001021195 d7cb1ef4a746e69116c5eda5b6e9c4a5 229 TIGRFAM TIGR02796 tolQ: protein TolQ 7 218 7.8E-92 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 MADE_000001021195 d7cb1ef4a746e69116c5eda5b6e9c4a5 229 Pfam PF01618 MotA/TolQ/ExbB proton channel family 81 205 1.9E-41 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MADE_000001020770 342439fc806ff382e7378f9e83b5e0d9 134 Gene3D G3DSA:3.40.190.10 18 133 4.2E-13 T 13-10-2018 MADE_000001020770 342439fc806ff382e7378f9e83b5e0d9 134 Pfam PF12849 PBP superfamily domain 14 124 2.4E-8 T 13-10-2018 IPR024370 PBP domain MADE_000001020770 342439fc806ff382e7378f9e83b5e0d9 134 SUPERFAMILY SSF53850 14 132 7.42E-17 T 13-10-2018 MADE_1009735 3e221448e339e099231b710f605fe75f 74 Gene3D G3DSA:3.40.630.30 1 61 1.1E-11 T 13-10-2018 MADE_1009735 3e221448e339e099231b710f605fe75f 74 SUPERFAMILY SSF55729 1 56 4.25E-12 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1009735 3e221448e339e099231b710f605fe75f 74 Pfam PF13673 Acetyltransferase (GNAT) domain 1 65 2.6E-5 T 13-10-2018 IPR000182 GNAT domain MADE_1018960 e172ec56d645c199eae3b66a58fb6134 95 Pfam PF07130 YebG protein 1 74 1.7E-29 T 13-10-2018 IPR009813 Uncharacterised protein family YebG MADE_1018960 e172ec56d645c199eae3b66a58fb6134 95 Gene3D G3DSA:1.10.10.710 21 89 2.2E-13 T 13-10-2018 IPR038627 YebG-like superfamily MADE_1007205 1430430ad03b17519a4233a0ecd96ffd 185 Gene3D G3DSA:3.10.129.10 2 163 3.0E-49 T 13-10-2018 MADE_1007205 1430430ad03b17519a4233a0ecd96ffd 185 Pfam PF03061 Thioesterase superfamily 25 98 1.8E-18 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MADE_1007205 1430430ad03b17519a4233a0ecd96ffd 185 SUPERFAMILY SSF54637 9 155 4.34E-42 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1000685 360a346a269cccda512154e3022292a8 408 Pfam PF06738 Putative threonine/serine exporter 12 252 2.6E-60 T 13-10-2018 IPR010619 Putative threonine/serine exporter MADE_1000685 360a346a269cccda512154e3022292a8 408 Pfam PF12821 Threonine/Serine exporter, ThrE 275 400 4.0E-13 T 13-10-2018 IPR024528 Threonine/Serine exporter, ThrE MADE_1015195 1f4b0386b882a47ac066a0374549ee2e 152 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 147 1.0E-65 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MADE_1015195 1f4b0386b882a47ac066a0374549ee2e 152 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 152 55.71 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MADE_1015195 1f4b0386b882a47ac066a0374549ee2e 152 SUPERFAMILY SSF89447 1 135 5.02E-44 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily MADE_1015195 1f4b0386b882a47ac066a0374549ee2e 152 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 152 4.1E-55 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 MADE_1015195 1f4b0386b882a47ac066a0374549ee2e 152 Pfam PF02381 MraZ protein, putative antitoxin-like 78 134 5.9E-17 T 13-10-2018 IPR020603 MraZ domain MADE_1015195 1f4b0386b882a47ac066a0374549ee2e 152 Pfam PF02381 MraZ protein, putative antitoxin-like 1 75 1.7E-21 T 13-10-2018 IPR020603 MraZ domain MADE_1015195 1f4b0386b882a47ac066a0374549ee2e 152 Gene3D G3DSA:2.40.330.20 1 148 7.6E-42 T 13-10-2018 IPR038619 MraZ superfamily MADE_1020475 3ea26d004f2e799c0a42431e7b8ad5df 156 SUPERFAMILY SSF81573 63 121 1.7E-14 T 13-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily MADE_1020475 3ea26d004f2e799c0a42431e7b8ad5df 156 Gene3D G3DSA:1.20.5.620 62 122 2.7E-20 T 13-10-2018 MADE_1020475 3ea26d004f2e799c0a42431e7b8ad5df 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 7.6E-53 T 13-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 MADE_1020475 3ea26d004f2e799c0a42431e7b8ad5df 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 3.1E-37 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MADE_1020475 3ea26d004f2e799c0a42431e7b8ad5df 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 13.189 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 MADE_1014940 3736bcd29376d7a61726528f94a1899a 236 Gene3D G3DSA:3.30.110.170 40 208 1.6E-8 T 13-10-2018 MADE_1014940 3736bcd29376d7a61726528f94a1899a 236 Gene3D G3DSA:3.30.70.2970 50 166 1.6E-8 T 13-10-2018 MADE_1014940 3736bcd29376d7a61726528f94a1899a 236 PIRSF PIRSF029033 1 236 6.3E-94 T 13-10-2018 IPR016907 Uncharacterised conserved protein UCP029033, periplasmic protein MADE_1014940 3736bcd29376d7a61726528f94a1899a 236 Pfam PF04402 Protein of unknown function (DUF541) 38 209 4.1E-15 T 13-10-2018 IPR007497 Protein of unknown function DUF541 MADE_1002225 7fb19ef39c73d7c767d2878d4db66dec 333 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 22 331 9.8E-100 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 MADE_1002225 7fb19ef39c73d7c767d2878d4db66dec 333 Gene3D G3DSA:3.30.470.10 4 327 1.7E-95 T 13-10-2018 MADE_1002225 7fb19ef39c73d7c767d2878d4db66dec 333 Pfam PF01063 Amino-transferase class IV 48 285 3.9E-29 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MADE_1002225 7fb19ef39c73d7c767d2878d4db66dec 333 PIRSF PIRSF006468 2 333 7.9E-100 T 13-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 MADE_1002225 7fb19ef39c73d7c767d2878d4db66dec 333 Gene3D G3DSA:3.20.10.10 150 314 1.7E-95 T 13-10-2018 MADE_1002225 7fb19ef39c73d7c767d2878d4db66dec 333 SUPERFAMILY SSF56752 2 328 1.27E-82 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MADE_1010050 f035fc0ef02594bc44409ec5985b5bb9 285 Pfam PF08241 Methyltransferase domain 105 161 2.1E-7 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MADE_1010050 f035fc0ef02594bc44409ec5985b5bb9 285 SUPERFAMILY SSF53335 111 250 8.13E-14 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1010050 f035fc0ef02594bc44409ec5985b5bb9 285 Gene3D G3DSA:3.40.50.150 78 228 1.3E-12 T 13-10-2018 MADE_1002555 53c7779339272db8071d321c5f9270c4 503 Gene3D G3DSA:3.30.70.1070 398 498 6.0E-14 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 SUPERFAMILY SSF47240 4 156 2.65E-49 T 13-10-2018 IPR009078 Ferritin-like superfamily MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 38 54 1.2E-12 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 62 78 1.2E-12 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 133 151 1.2E-12 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 Gene3D G3DSA:1.20.1260.10 1 157 6.3E-61 T 13-10-2018 IPR012347 Ferritin-like MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 ProSitePatterns PS00818 Dps protein family signature 1. 38 54 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 PIRSF PIRSF005900 1 157 5.4E-52 T 13-10-2018 IPR002177 DNA-binding protein Dps MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 ProSitePatterns PS00819 Dps protein family signature 2. 64 78 - T 13-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 MADE_1002895 4fc70882b58f7a8fbfe4ec4656b9a801 157 Pfam PF00210 Ferritin-like domain 18 155 2.4E-32 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 MADE_1001280 271c943cb7974edccf3099a95e2d1840 251 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 7.7E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001280 271c943cb7974edccf3099a95e2d1840 251 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001280 271c943cb7974edccf3099a95e2d1840 251 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 31 1.6E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1009055 a56d223e2b22464725967104806ff3b4 779 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 158 5.2E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1009055 a56d223e2b22464725967104806ff3b4 779 Gene3D G3DSA:2.40.170.20 171 779 5.9E-65 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1009055 a56d223e2b22464725967104806ff3b4 779 SUPERFAMILY SSF56935 21 779 1.9E-89 T 13-10-2018 MADE_1009055 a56d223e2b22464725967104806ff3b4 779 Gene3D G3DSA:2.170.130.10 56 170 6.7E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1009055 a56d223e2b22464725967104806ff3b4 779 Pfam PF00593 TonB dependent receptor 257 777 1.8E-23 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1018485 eebabec22a170a67570b3f140faef01a 768 Gene3D G3DSA:2.170.130.10 59 186 6.3E-35 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1018485 eebabec22a170a67570b3f140faef01a 768 Gene3D G3DSA:2.40.170.20 190 768 3.3E-104 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1018485 eebabec22a170a67570b3f140faef01a 768 Pfam PF00593 TonB dependent receptor 245 766 3.9E-37 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1018485 eebabec22a170a67570b3f140faef01a 768 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 175 2.3E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1018485 eebabec22a170a67570b3f140faef01a 768 SUPERFAMILY SSF56935 74 768 3.82E-109 T 13-10-2018 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 PIRSF PIRSF017184 12 499 3.9E-130 T 13-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 16 217 22.576 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 Pfam PF03853 YjeF-related protein N-terminus 37 196 1.2E-37 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 18 216 4.0E-42 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 231 498 22.378 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 SUPERFAMILY SSF53613 240 498 3.74E-72 T 13-10-2018 IPR029056 Ribokinase-like MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 437 447 - T 13-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 SUPERFAMILY SSF64153 14 253 8.11E-58 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 Pfam PF01256 Carbohydrate kinase 255 492 1.1E-58 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 Gene3D G3DSA:3.40.1190.20 234 499 1.1E-84 T 13-10-2018 IPR029056 Ribokinase-like MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 240 497 2.0E-68 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 MADE_000001023575 61f7930facd5d1ebaff431b5a61be416 499 Gene3D G3DSA:3.40.50.10260 10 222 5.9E-58 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 MADE_1020330 f3ae1ab5fcf5187ea5ca06e7e87e6be7 1085 Gene3D G3DSA:3.40.50.300 295 497 8.5E-41 T 13-10-2018 MADE_1020330 f3ae1ab5fcf5187ea5ca06e7e87e6be7 1085 Pfam PF00270 DEAD/DEAH box helicase 328 470 1.3E-18 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1020330 f3ae1ab5fcf5187ea5ca06e7e87e6be7 1085 SMART SM00490 628 716 2.1E-7 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1020330 f3ae1ab5fcf5187ea5ca06e7e87e6be7 1085 SUPERFAMILY SSF52540 330 723 1.92E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020330 f3ae1ab5fcf5187ea5ca06e7e87e6be7 1085 Gene3D G3DSA:3.40.50.300 560 745 1.2E-24 T 13-10-2018 MADE_1020330 f3ae1ab5fcf5187ea5ca06e7e87e6be7 1085 SMART SM00487 306 489 3.6E-15 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1004630 10a26161bfa34cf2b1c34fe96e1c4083 331 Gene3D G3DSA:3.40.1550.10 132 325 1.2E-35 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1004630 10a26161bfa34cf2b1c34fe96e1c4083 331 SMART SM00448 2 114 2.1E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004630 10a26161bfa34cf2b1c34fe96e1c4083 331 SUPERFAMILY SSF103039 133 325 1.13E-43 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1004630 10a26161bfa34cf2b1c34fe96e1c4083 331 Gene3D G3DSA:3.40.50.2300 1 128 1.6E-28 T 13-10-2018 MADE_1004630 10a26161bfa34cf2b1c34fe96e1c4083 331 Pfam PF00072 Response regulator receiver domain 4 114 2.4E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004630 10a26161bfa34cf2b1c34fe96e1c4083 331 SUPERFAMILY SSF52172 1 149 6.83E-29 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 Gene3D G3DSA:3.40.50.1480 9 366 2.8E-102 T 13-10-2018 MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 Gene3D G3DSA:3.40.50.720 172 329 2.8E-102 T 13-10-2018 MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 19 130 1.9E-11 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 SUPERFAMILY SSF52283 7 366 5.19E-25 T 13-10-2018 MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 184 327 1.9E-36 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 SUPERFAMILY SSF51735 170 329 4.17E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 SMART SM00996 1 369 1.8E-13 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MADE_1016330 0ac4568da0c44d112e4b3416a355c59f 372 SMART SM00997 170 329 2.7E-65 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 SUPERFAMILY SSF46785 8 92 3.91E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 SMART SM00418 13 91 7.1E-28 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 Gene3D G3DSA:1.10.10.10 6 98 4.9E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 Pfam PF01022 Bacterial regulatory protein, arsR family 21 65 3.3E-16 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 4.6E-22 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 4.6E-22 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 4.6E-22 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 46 4.6E-22 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 MADE_1015505 161db6b9b5f9824d6618e12ed69d4cff 113 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 37 55 - T 13-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 MADE_1019155 6a1b82cd0c7ae5345e580a55ac1c40aa 138 Pfam PF00472 RF-1 domain 8 133 1.8E-21 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MADE_1019155 6a1b82cd0c7ae5345e580a55ac1c40aa 138 SUPERFAMILY SSF75620 8 114 7.06E-11 T 13-10-2018 MADE_1019155 6a1b82cd0c7ae5345e580a55ac1c40aa 138 Gene3D G3DSA:3.30.160.20 2 137 7.5E-37 T 13-10-2018 MADE_1019155 6a1b82cd0c7ae5345e580a55ac1c40aa 138 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 22 38 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MADE_1015640 dd9171a6f80660d1b5187d43f0914c5f 198 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 32 187 2.0E-63 T 13-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 MADE_1015640 dd9171a6f80660d1b5187d43f0914c5f 198 Pfam PF13580 SIS domain 9 144 4.4E-35 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MADE_1015640 dd9171a6f80660d1b5187d43f0914c5f 198 SUPERFAMILY SSF53697 1 189 7.42E-57 T 13-10-2018 MADE_1015640 dd9171a6f80660d1b5187d43f0914c5f 198 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 37.004 T 13-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 MADE_1015640 dd9171a6f80660d1b5187d43f0914c5f 198 Gene3D G3DSA:3.40.50.10490 1 195 5.6E-77 T 13-10-2018 MADE_1020395 9f5bde2e8cb1c4c25927054c36ee3bf3 363 Gene3D G3DSA:1.10.3290.10 44 278 3.6E-37 T 13-10-2018 IPR036597 Fido-like domain superfamily MADE_1020395 9f5bde2e8cb1c4c25927054c36ee3bf3 363 SUPERFAMILY SSF140931 94 280 4.19E-33 T 13-10-2018 IPR036597 Fido-like domain superfamily MADE_1020395 9f5bde2e8cb1c4c25927054c36ee3bf3 363 Pfam PF13784 Fic/DOC family N-terminal 28 107 7.3E-23 T 13-10-2018 IPR025758 Fic/DOC N-terminal MADE_1020395 9f5bde2e8cb1c4c25927054c36ee3bf3 363 PIRSF PIRSF038925 2 360 3.9E-113 T 13-10-2018 IPR026287 Adenosine monophosphate-protein transferase MADE_1020395 9f5bde2e8cb1c4c25927054c36ee3bf3 363 Pfam PF02661 Fic/DOC family 136 213 1.2E-16 T 13-10-2018 IPR003812 Fido domain MADE_000001021250 80f203993f6f0aaa4bfaec5c7dd97370 339 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 182 320 3.8E-27 T 13-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain MADE_000001021250 80f203993f6f0aaa4bfaec5c7dd97370 339 SUPERFAMILY SSF48179 182 322 2.52E-24 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 MADE_000001021250 80f203993f6f0aaa4bfaec5c7dd97370 339 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 323 2.2E-64 T 13-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 MADE_000001021250 80f203993f6f0aaa4bfaec5c7dd97370 339 Gene3D G3DSA:1.10.1040.10 183 326 2.6E-32 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 MADE_000001021250 80f203993f6f0aaa4bfaec5c7dd97370 339 Gene3D G3DSA:3.40.50.720 3 182 2.1E-38 T 13-10-2018 MADE_000001021250 80f203993f6f0aaa4bfaec5c7dd97370 339 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 158 9.0E-35 T 13-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain MADE_000001021250 80f203993f6f0aaa4bfaec5c7dd97370 339 SUPERFAMILY SSF51735 3 132 3.26E-14 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1019935 b7679c033e85beca4e498c3830f63c0c 344 SUPERFAMILY SSF53474 34 310 1.09E-35 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1019935 b7679c033e85beca4e498c3830f63c0c 344 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 237 278 - T 13-10-2018 IPR000952 AB hydrolase 4, conserved site MADE_1019935 b7679c033e85beca4e498c3830f63c0c 344 Pfam PF00561 alpha/beta hydrolase fold 70 312 1.7E-13 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1019935 b7679c033e85beca4e498c3830f63c0c 344 Gene3D G3DSA:3.40.50.1820 56 332 2.4E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1019935 b7679c033e85beca4e498c3830f63c0c 344 PIRSF PIRSF005211 1 337 2.2E-99 T 13-10-2018 IPR012020 AB hydrolase 4 family MADE_1010855 b9dd80ccdce55103898c09c60b5a9115 117 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 117 3.6E-46 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 MADE_1010855 b9dd80ccdce55103898c09c60b5a9115 117 Pfam PF03960 ArsC family 11 116 9.7E-18 T 13-10-2018 IPR006660 Arsenate reductase-like MADE_1010855 b9dd80ccdce55103898c09c60b5a9115 117 SUPERFAMILY SSF52833 3 117 2.24E-31 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1010855 b9dd80ccdce55103898c09c60b5a9115 117 Gene3D G3DSA:3.40.30.10 1 117 1.2E-46 T 13-10-2018 MADE_1016925 6e84286d3f563051b4f3cad050ea3071 183 Gene3D G3DSA:1.20.120.20 22 182 1.2E-5 T 13-10-2018 MADE_1016925 6e84286d3f563051b4f3cad050ea3071 183 SUPERFAMILY SSF58113 41 160 4.45E-5 T 13-10-2018 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Hamap MF_01113 DNA polymerase IV [dinB]. 1 352 36.941 T 13-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Pfam PF00817 impB/mucB/samB family 7 154 6.9E-48 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 348 6.5E-9 T 13-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Gene3D G3DSA:2.30.40.20 21 73 8.7E-62 T 13-10-2018 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 SUPERFAMILY SSF100879 241 354 8.79E-25 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Gene3D G3DSA:3.30.70.270 4 164 8.7E-62 T 13-10-2018 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Pfam PF11798 IMS family HHH motif 166 197 1.9E-7 T 13-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Gene3D G3DSA:3.30.1490.100 237 354 3.5E-26 T 13-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 Gene3D G3DSA:1.10.150.20 176 229 1.1E-17 T 13-10-2018 MADE_000001022945 1726c008c8e1cf4c34ef525751c35a4c 357 SUPERFAMILY SSF56672 1 233 1.07E-91 T 13-10-2018 MADE_1008125 701be5080e70ea3e0f5818a3ef2729fd 246 SUPERFAMILY SSF89550 2 205 7.85E-13 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MADE_1008125 701be5080e70ea3e0f5818a3ef2729fd 246 Gene3D G3DSA:3.20.20.140 1 243 3.6E-71 T 13-10-2018 MADE_1008125 701be5080e70ea3e0f5818a3ef2729fd 246 PIRSF PIRSF016557 1 239 4.4E-61 T 13-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 SUPERFAMILY SSF46689 14 97 2.82E-23 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 Gene3D G3DSA:1.10.10.60 1 97 2.8E-29 T 13-10-2018 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 Pfam PF02954 Bacterial regulatory protein, Fis family 54 94 8.8E-14 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 PIRSF PIRSF002097 1 97 4.5E-39 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 60 77 1.7E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 77 97 1.7E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 PRINTS PR01591 DNA-binding protein FIS signature 8 25 3.7E-16 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 PRINTS PR01591 DNA-binding protein FIS signature 41 56 3.7E-16 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 PRINTS PR01591 DNA-binding protein FIS signature 56 68 3.7E-16 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MADE_1019735 670d68b108d40b5017e90a6d49fa110d 97 PRINTS PR01591 DNA-binding protein FIS signature 25 41 3.7E-16 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 MADE_1003300 1bb627c2beaa3bb36f4753c916a43bc7 322 SUPERFAMILY SSF56349 5 307 1.12E-44 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1003300 1bb627c2beaa3bb36f4753c916a43bc7 322 Gene3D G3DSA:1.10.150.130 1 94 2.7E-26 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1003300 1bb627c2beaa3bb36f4753c916a43bc7 322 Gene3D G3DSA:1.10.443.10 97 310 1.4E-66 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1003300 1bb627c2beaa3bb36f4753c916a43bc7 322 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 6 88 3.5E-21 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 MADE_1003300 1bb627c2beaa3bb36f4753c916a43bc7 322 TIGRFAM TIGR02249 integrase_gron: integron integrase 5 320 6.0E-132 T 13-10-2018 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 MADE_1003300 1bb627c2beaa3bb36f4753c916a43bc7 322 Pfam PF00589 Phage integrase family 105 306 3.2E-44 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1016640 7585af30b87ecfc35bf26b9811d52ba4 391 Gene3D G3DSA:3.90.1150.10 49 367 7.5E-79 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1016640 7585af30b87ecfc35bf26b9811d52ba4 391 Gene3D G3DSA:3.40.640.10 65 287 7.5E-79 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1016640 7585af30b87ecfc35bf26b9811d52ba4 391 Pfam PF00155 Aminotransferase class I and II 51 377 2.3E-43 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1016640 7585af30b87ecfc35bf26b9811d52ba4 391 SUPERFAMILY SSF53383 47 381 5.24E-63 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1012220 bd5af3a83c282a9f5c3101615a381cfc 218 PIRSF PIRSF004982 1 183 3.7E-45 T 13-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 MADE_1012220 bd5af3a83c282a9f5c3101615a381cfc 218 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 8 173 1.1E-29 T 13-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 MADE_1012220 bd5af3a83c282a9f5c3101615a381cfc 218 Pfam PF03843 Outer membrane lipoprotein Slp family 14 163 2.5E-42 T 13-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 Gene3D G3DSA:3.10.580.10 143 269 6.6E-33 T 13-10-2018 MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 SUPERFAMILY SSF51206 8 128 8.71E-10 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 SMART SM00116 155 202 1.9E-7 T 13-10-2018 IPR000644 CBS domain MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 SMART SM00116 219 268 2.8E-8 T 13-10-2018 IPR000644 CBS domain MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 SUPERFAMILY SSF54631 150 268 1.64E-28 T 13-10-2018 MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 Gene3D G3DSA:2.60.120.10 1 131 5.2E-7 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 465 608 4.3E-33 T 13-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 Pfam PF03445 Putative nucleotidyltransferase DUF294 295 428 2.2E-35 T 13-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 Pfam PF00571 CBS domain 150 201 1.3E-9 T 13-10-2018 IPR000644 CBS domain MADE_000001023085 abd097145ba31ef263d502f42f0a73d1 613 Pfam PF00571 CBS domain 212 266 3.8E-10 T 13-10-2018 IPR000644 CBS domain MADE_1007960 454722b785e0bd67cd846ab29c59363e 443 Pfam PF00860 Permease family 21 399 9.2E-49 T 13-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 MADE_1007960 454722b785e0bd67cd846ab29c59363e 443 PIRSF PIRSF005353 1 443 1.3E-176 T 13-10-2018 IPR026033 Purine permease PbuG-like MADE_1003040 3839617c6decedff9764bd7d0c0f0d44 140 SMART SM00670 2 120 6.6E-7 T 13-10-2018 IPR002716 PIN domain MADE_1003040 3839617c6decedff9764bd7d0c0f0d44 140 Pfam PF13470 PIN domain 3 116 8.6E-19 T 13-10-2018 IPR002716 PIN domain MADE_1003040 3839617c6decedff9764bd7d0c0f0d44 140 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 3 114 3.1E-20 T 13-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component MADE_1003040 3839617c6decedff9764bd7d0c0f0d44 140 SUPERFAMILY SSF88723 1 121 1.26E-11 T 13-10-2018 IPR029060 PIN-like domain superfamily MADE_1000585 2a61f96c3bd6e3dc589c9d61a8938635 1077 SUPERFAMILY SSF52540 44 207 5.2E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000585 2a61f96c3bd6e3dc589c9d61a8938635 1077 Gene3D G3DSA:3.40.50.300 34 223 2.0E-6 T 13-10-2018 MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 6 225 33.734 T 13-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 SUPERFAMILY SSF56784 3 222 7.74E-63 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 Gene3D G3DSA:1.10.150.240 21 94 3.8E-66 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 111 188 3.2E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 194 5.2E-11 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 10 222 4.9E-67 T 13-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 194 6.0E-37 T 13-10-2018 MADE_1010940 2138f2592ba9d4647afc624e7f9b87af 225 Gene3D G3DSA:3.40.50.1000 10 217 3.8E-66 T 13-10-2018 IPR023214 HAD superfamily MADE_1008880 d743a51419907a0e8de39ef59d67f8a4 54 Pfam PF08085 Entericidin EcnA/B family 30 49 3.1E-8 T 13-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 MADE_1005680 f41dccdc3bc2bd96f8817755ad1a89ee 143 Gene3D G3DSA:1.20.58.300 2 98 7.1E-6 T 13-10-2018 MADE_1005680 f41dccdc3bc2bd96f8817755ad1a89ee 143 SUPERFAMILY SSF140566 5 114 4.32E-13 T 13-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 MADE_1005680 f41dccdc3bc2bd96f8817755ad1a89ee 143 Pfam PF05130 FlgN protein 7 133 3.4E-15 T 13-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 MADE_1016780 687daed5c461558301b1adee2723b092 380 Pfam PF00589 Phage integrase family 202 364 7.0E-21 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1016780 687daed5c461558301b1adee2723b092 380 Gene3D G3DSA:1.10.443.10 199 379 8.0E-27 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1016780 687daed5c461558301b1adee2723b092 380 SUPERFAMILY SSF56349 88 370 2.8E-41 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_000001022925 e71eb4ef9a1928f322108a3a0473c9ad 297 Pfam PF04116 Fatty acid hydroxylase superfamily 82 231 4.2E-24 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MADE_1003320 6458c43c85170de974dfaefdd225c067 443 Gene3D G3DSA:3.90.230.10 159 442 2.1E-82 T 13-10-2018 MADE_1003320 6458c43c85170de974dfaefdd225c067 443 Hamap MF_01279 Xaa-Pro dipeptidase [pepQ]. 1 443 59.334 T 13-10-2018 IPR022846 Xaa-Pro dipeptidase GO:0016795 MADE_1003320 6458c43c85170de974dfaefdd225c067 443 Pfam PF00557 Metallopeptidase family M24 166 429 2.2E-47 T 13-10-2018 IPR000994 Peptidase M24 MADE_1003320 6458c43c85170de974dfaefdd225c067 443 SUPERFAMILY SSF55920 161 439 4.71E-58 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like MADE_1003320 6458c43c85170de974dfaefdd225c067 443 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 335 347 - T 13-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site MADE_1003320 6458c43c85170de974dfaefdd225c067 443 Gene3D G3DSA:3.40.350.10 1 157 4.7E-67 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 1.8E-76 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 SUPERFAMILY SSF51905 2 314 3.78E-50 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 300 9.1E-50 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 8.8E-40 T 13-10-2018 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 8.8E-40 T 13-10-2018 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 8.8E-40 T 13-10-2018 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 8.8E-40 T 13-10-2018 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 8.8E-40 T 13-10-2018 MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 Gene3D G3DSA:3.50.50.60 118 244 1.4E-124 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 Gene3D G3DSA:3.50.50.60 9 312 1.4E-124 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_000001021740 cabb5b6ac5b52ed3fd642e4656e85a39 321 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 9 313 2.1E-121 T 13-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 MADE_000001021350 ddcaf2a27ee83964212a9fb11c39d84c 366 SMART SM00267 189 360 3.7E-55 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021350 ddcaf2a27ee83964212a9fb11c39d84c 366 SUPERFAMILY SSF55073 205 359 2.04E-46 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001021350 ddcaf2a27ee83964212a9fb11c39d84c 366 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 197 359 9.5E-47 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021350 ddcaf2a27ee83964212a9fb11c39d84c 366 Gene3D G3DSA:3.30.70.270 193 362 2.5E-55 T 13-10-2018 MADE_000001021350 ddcaf2a27ee83964212a9fb11c39d84c 366 Pfam PF00990 Diguanylate cyclase, GGDEF domain 200 355 3.1E-43 T 13-10-2018 IPR000160 GGDEF domain MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 359 367 - T 13-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 SMART SM01060 29 417 1.5E-274 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 SUPERFAMILY SSF52317 544 657 6.11E-14 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 Pfam PF06628 Catalase-related immune-responsive 444 508 1.9E-21 T 13-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 PRINTS PR00067 Catalase signature 105 123 1.2E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 PRINTS PR00067 Catalase signature 145 163 1.2E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 PRINTS PR00067 Catalase signature 42 65 1.2E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 PRINTS PR00067 Catalase signature 346 372 1.2E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 PRINTS PR00067 Catalase signature 126 143 1.2E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 PRINTS PR00067 Catalase signature 314 341 1.2E-65 T 13-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 Gene3D G3DSA:2.40.180.10 4 439 1.6E-203 T 13-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 Gene3D G3DSA:3.40.50.880 545 689 7.9E-28 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 ProSitePatterns PS00438 Catalase proximal active site signature. 65 81 - T 13-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 PIRSF PIRSF038927 3 689 0.0 T 13-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 SUPERFAMILY SSF56634 20 515 8.64E-218 T 13-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 Pfam PF00199 Catalase 29 413 7.4E-182 T 13-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 MADE_1009965 f9d1f8de51ba2d65faec4397ad54281e 689 Gene3D G3DSA:1.20.1370.20 442 544 4.4E-31 T 13-10-2018 MADE_1010950 6d9b4a4e85293eaf7abfb9c63a220ec3 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 424 1.1E-95 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_1010950 6d9b4a4e85293eaf7abfb9c63a220ec3 457 PIRSF PIRSF006603 3 454 3.5E-59 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_1010950 6d9b4a4e85293eaf7abfb9c63a220ec3 457 Pfam PF01554 MatE 245 405 2.8E-32 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_1010950 6d9b4a4e85293eaf7abfb9c63a220ec3 457 Pfam PF01554 MatE 19 178 5.1E-28 T 13-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 MADE_000001023010 ac29ef54edca67e014476f18cc35a7a3 133 Gene3D G3DSA:1.10.520.10 1 31 1.9E-11 T 13-10-2018 MADE_000001023010 ac29ef54edca67e014476f18cc35a7a3 133 SUPERFAMILY SSF48113 1 100 2.65E-37 T 13-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_000001023010 ac29ef54edca67e014476f18cc35a7a3 133 Gene3D G3DSA:1.10.420.20 32 100 1.6E-33 T 13-10-2018 MADE_000001023010 ac29ef54edca67e014476f18cc35a7a3 133 Pfam PF00141 Peroxidase 1 83 3.4E-18 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 MADE_1002830 244c609f79525d6baab8620d224f7728 258 Gene3D G3DSA:3.20.20.140 2 258 2.0E-86 T 13-10-2018 MADE_1002830 244c609f79525d6baab8620d224f7728 258 Pfam PF01026 TatD related DNase 4 256 8.9E-66 T 13-10-2018 IPR001130 TatD family GO:0016788 MADE_1002830 244c609f79525d6baab8620d224f7728 258 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MADE_1002830 244c609f79525d6baab8620d224f7728 258 SUPERFAMILY SSF51556 3 257 1.36E-79 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1002830 244c609f79525d6baab8620d224f7728 258 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 MADE_1002830 244c609f79525d6baab8620d224f7728 258 PIRSF PIRSF005902 1 258 2.0E-72 T 13-10-2018 IPR001130 TatD family GO:0016788 MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 SUPERFAMILY SSF55594 4 89 1.57E-26 T 13-10-2018 IPR035895 HPr-like superfamily MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 13-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 83 5.2E-27 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 Pfam PF00381 PTS HPr component phosphorylation site 4 83 8.2E-27 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 PRINTS PR00107 Phosphocarrier protein signature 14 30 1.8E-11 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 PRINTS PR00107 Phosphocarrier protein signature 54 71 1.8E-11 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 PRINTS PR00107 Phosphocarrier protein signature 39 54 1.8E-11 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like MADE_1004165 0124bdfd31d0c93b69c190ae60903960 90 Gene3D G3DSA:3.30.1340.10 3 89 5.0E-29 T 13-10-2018 IPR035895 HPr-like superfamily MADE_1002730 02ce1dacde994609c946d8ff1a2bff1f 313 Gene3D G3DSA:3.20.20.370 18 248 2.3E-72 T 13-10-2018 MADE_1002730 02ce1dacde994609c946d8ff1a2bff1f 313 SUPERFAMILY SSF88713 27 237 6.23E-64 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MADE_1002730 02ce1dacde994609c946d8ff1a2bff1f 313 Pfam PF04748 Divergent polysaccharide deacetylase 30 238 4.0E-70 T 13-10-2018 IPR006837 Divergent polysaccharide deacetylase MADE_1014895 8ab9b0b1912dbc3bffb48d108a6606fb 313 Gene3D G3DSA:3.90.245.10 1 312 1.0E-105 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like MADE_1014895 8ab9b0b1912dbc3bffb48d108a6606fb 313 SUPERFAMILY SSF53590 1 311 4.06E-93 T 13-10-2018 IPR036452 Ribonucleoside hydrolase-like MADE_1014895 8ab9b0b1912dbc3bffb48d108a6606fb 313 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 303 6.0E-82 T 13-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain MADE_1010635 7b891e91707115ded3150c4a4a494705 286 Gene3D G3DSA:3.40.830.10 1 278 2.5E-74 T 13-10-2018 MADE_1010635 7b891e91707115ded3150c4a4a494705 286 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 10 264 1.2E-37 T 13-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 MADE_1010635 7b891e91707115ded3150c4a4a494705 286 SUPERFAMILY SSF53213 9 264 1.57E-67 T 13-10-2018 MADE_1010635 7b891e91707115ded3150c4a4a494705 286 PIRSF PIRSF006157 3 284 1.1E-72 T 13-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 MADE_1001895 54c33f2988ecef620b8fa0740b8779b7 156 Pfam PF13474 SnoaL-like domain 44 155 2.3E-9 T 13-10-2018 IPR037401 SnoaL-like domain MADE_1001895 54c33f2988ecef620b8fa0740b8779b7 156 Gene3D G3DSA:3.10.450.50 32 155 1.3E-34 T 13-10-2018 MADE_1001895 54c33f2988ecef620b8fa0740b8779b7 156 SUPERFAMILY SSF54427 42 155 4.28E-24 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1013365 a29242311415126d600546d5c8a1224d 244 SUPERFAMILY SSF50891 107 238 4.17E-36 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1013365 a29242311415126d600546d5c8a1224d 244 Gene3D G3DSA:3.30.1360.40 10 90 1.7E-14 T 13-10-2018 MADE_1013365 a29242311415126d600546d5c8a1224d 244 Gene3D G3DSA:2.40.100.10 106 243 2.4E-46 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily MADE_1013365 a29242311415126d600546d5c8a1224d 244 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 10 211 3.4E-52 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MADE_1013365 a29242311415126d600546d5c8a1224d 244 SUPERFAMILY SSF160467 9 112 1.31E-13 T 13-10-2018 MADE_1013365 a29242311415126d600546d5c8a1224d 244 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 29 231 1.3E-44 T 13-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 MADE_1013365 a29242311415126d600546d5c8a1224d 244 SMART SM00796 8 222 2.0E-52 T 13-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D MADE_1003810 06ec7dea520d2ec5c8b362e8796fe5f0 266 Pfam PF02673 Bacitracin resistance protein BacA 7 259 2.4E-82 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MADE_1003810 06ec7dea520d2ec5c8b362e8796fe5f0 266 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 264 17.668 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MADE_1003810 06ec7dea520d2ec5c8b362e8796fe5f0 266 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 7 257 4.3E-74 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 MADE_000001021205 dad36e0c359f17d48b2057057f7220f7 293 SUPERFAMILY SSF74653 207 292 5.89E-20 T 13-10-2018 MADE_000001021205 dad36e0c359f17d48b2057057f7220f7 293 Pfam PF06519 TolA C-terminal 198 291 7.7E-32 T 13-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 MADE_000001021205 dad36e0c359f17d48b2057057f7220f7 293 Gene3D G3DSA:3.30.1150.10 196 292 1.3E-29 T 13-10-2018 MADE_000001021205 dad36e0c359f17d48b2057057f7220f7 293 TIGRFAM TIGR02794 tolA_full: protein TolA 90 292 6.1E-37 T 13-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 MADE_1012320 d61d23d5d32eea50301f71ed7e3c09f7 245 SUPERFAMILY SSF51366 1 242 1.82E-67 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MADE_1012320 d61d23d5d32eea50301f71ed7e3c09f7 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 241 35.345 T 13-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MADE_1012320 d61d23d5d32eea50301f71ed7e3c09f7 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 238 5.3E-80 T 13-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 MADE_1012320 d61d23d5d32eea50301f71ed7e3c09f7 245 Pfam PF00977 Histidine biosynthesis protein 1 234 4.3E-78 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 MADE_1012320 d61d23d5d32eea50301f71ed7e3c09f7 245 Gene3D G3DSA:3.20.20.70 1 245 1.7E-94 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1009545 bce81c5df5b6a8782c8133f27015eba3 182 Gene3D G3DSA:3.40.1280.10 22 164 1.3E-17 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_1009545 bce81c5df5b6a8782c8133f27015eba3 182 Pfam PF00588 SpoU rRNA Methylase family 21 154 6.2E-18 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MADE_1009545 bce81c5df5b6a8782c8133f27015eba3 182 SUPERFAMILY SSF75217 13 158 1.18E-27 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_1001735 f9b2a361cf50209a81489e16026ccb98 217 Pfam PF04191 Phospholipid methyltransferase 123 192 3.1E-7 T 13-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 MADE_1001735 f9b2a361cf50209a81489e16026ccb98 217 Gene3D G3DSA:1.20.120.1630 7 208 4.2E-24 T 13-10-2018 MADE_000001022110 d5f53871a5419d88420778dc801f6950 223 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 217 1.1E-81 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MADE_000001022110 d5f53871a5419d88420778dc801f6950 223 Gene3D G3DSA:3.40.50.300 2 223 1.7E-84 T 13-10-2018 MADE_000001022110 d5f53871a5419d88420778dc801f6950 223 Pfam PF02224 Cytidylate kinase 7 219 7.8E-77 T 13-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MADE_000001022110 d5f53871a5419d88420778dc801f6950 223 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 35.109 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 MADE_000001022110 d5f53871a5419d88420778dc801f6950 223 SUPERFAMILY SSF52540 5 222 6.2E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018470 1212d71c7a7be9b5235dd06bfc013f3c 310 SUPERFAMILY SSF52540 4 232 1.63E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018470 1212d71c7a7be9b5235dd06bfc013f3c 310 Gene3D G3DSA:3.40.50.300 1 236 2.1E-66 T 13-10-2018 MADE_1018470 1212d71c7a7be9b5235dd06bfc013f3c 310 Pfam PF00005 ABC transporter 20 164 5.2E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1018470 1212d71c7a7be9b5235dd06bfc013f3c 310 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1018470 1212d71c7a7be9b5235dd06bfc013f3c 310 SMART SM00382 29 211 1.0E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 11 83 1.0E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 Gene3D G3DSA:3.40.50.1000 1 115 1.6E-37 T 13-10-2018 IPR023214 HAD superfamily MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 53 73 6.0E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 17 6.0E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 80 93 6.0E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 35 51 6.0E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 SUPERFAMILY SSF56784 1 115 1.06E-29 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1008645 7bb3d7c11c99198bf9be818545f5a3ae 123 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 89 2.9E-13 T 13-10-2018 MADE_1014045 124c55683f3546fb8b256197bb9bce9f 51 Gene3D G3DSA:3.40.1260.10 1 48 1.4E-5 T 13-10-2018 IPR027396 DsrEFH-like MADE_1014045 124c55683f3546fb8b256197bb9bce9f 51 SUPERFAMILY SSF75169 1 51 5.05E-13 T 13-10-2018 IPR027396 DsrEFH-like MADE_1014045 124c55683f3546fb8b256197bb9bce9f 51 Pfam PF02635 DsrE/DsrF-like family 2 48 5.0E-10 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 Gene3D G3DSA:2.30.110.10 1 212 1.2E-75 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 SUPERFAMILY SSF50475 10 212 5.3E-62 T 13-10-2018 MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 32 115 4.3E-20 T 13-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 212 1.5E-19 T 13-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 212 1.1E-82 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 212 37.833 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 13-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MADE_1012505 3955cb4564392cfd27d3e9b120ba40c2 212 PIRSF PIRSF000190 1 212 3.3E-79 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 MADE_1006320 045457ccb359df1b45d465c6bf3c1ed6 162 Gene3D G3DSA:3.40.630.30 10 160 5.2E-36 T 13-10-2018 MADE_1006320 045457ccb359df1b45d465c6bf3c1ed6 162 Pfam PF00583 Acetyltransferase (GNAT) family 30 125 2.8E-18 T 13-10-2018 IPR000182 GNAT domain MADE_1006320 045457ccb359df1b45d465c6bf3c1ed6 162 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 21 140 8.7E-33 T 13-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 MADE_1006320 045457ccb359df1b45d465c6bf3c1ed6 162 SUPERFAMILY SSF55729 12 138 2.49E-29 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1002115 241f472f1fcc9b779c6d0b14b963920b 205 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 42 188 4.1E-30 T 13-10-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 MADE_1003050 4ef396828ad106a27676e29f36312167 81 SUPERFAMILY SSF47598 32 72 2.0E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_000001021705 43ad9c05faa046c9e14eb085649f0740 180 Gene3D G3DSA:3.30.70.1560 71 170 2.7E-41 T 13-10-2018 MADE_000001021705 43ad9c05faa046c9e14eb085649f0740 180 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 42 56 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 MADE_000001021705 43ad9c05faa046c9e14eb085649f0740 180 SUPERFAMILY SSF55120 6 179 2.24E-41 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_000001021705 43ad9c05faa046c9e14eb085649f0740 180 Pfam PF00849 RNA pseudouridylate synthase 7 151 2.1E-17 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_000001021705 43ad9c05faa046c9e14eb085649f0740 180 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 11 177 3.4E-57 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 MADE_000001021705 43ad9c05faa046c9e14eb085649f0740 180 Gene3D G3DSA:3.30.70.580 1 70 2.5E-27 T 13-10-2018 MADE_1000705 250b652431933d789a0bd70142a4f472 69 SUPERFAMILY SSF54285 4 69 1.26E-14 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MADE_1000705 250b652431933d789a0bd70142a4f472 69 Pfam PF02597 ThiS family 8 69 5.6E-9 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MADE_1000705 250b652431933d789a0bd70142a4f472 69 Gene3D G3DSA:3.10.20.30 4 69 6.8E-18 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1000705 250b652431933d789a0bd70142a4f472 69 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 7 69 8.8E-15 T 13-10-2018 IPR010035 ThiS, thiamine-biosynthesis MADE_1013660 581f44386208c40ecc84c095549992f9 461 SMART SM00849 21 221 5.0E-19 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1013660 581f44386208c40ecc84c095549992f9 461 Gene3D G3DSA:3.40.50.10710 224 373 3.2E-146 T 13-10-2018 MADE_1013660 581f44386208c40ecc84c095549992f9 461 Gene3D G3DSA:3.60.15.10 13 456 3.2E-146 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1013660 581f44386208c40ecc84c095549992f9 461 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 381 430 8.1E-7 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain MADE_1013660 581f44386208c40ecc84c095549992f9 461 Pfam PF00753 Metallo-beta-lactamase superfamily 26 180 6.9E-13 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1013660 581f44386208c40ecc84c095549992f9 461 SUPERFAMILY SSF56281 11 440 1.41E-73 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1015340 0a7b8d1a207abc9b237887b944d34c72 370 SUPERFAMILY SSF52540 2 335 6.01E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015340 0a7b8d1a207abc9b237887b944d34c72 370 Pfam PF00437 Type II/IV secretion system protein 47 268 1.3E-38 T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1015340 0a7b8d1a207abc9b237887b944d34c72 370 SMART SM00382 121 246 2.2E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1015340 0a7b8d1a207abc9b237887b944d34c72 370 Gene3D G3DSA:3.40.50.300 100 354 1.2E-88 T 13-10-2018 MADE_1015340 0a7b8d1a207abc9b237887b944d34c72 370 Gene3D G3DSA:3.30.450.90 1 98 2.8E-25 T 13-10-2018 MADE_1015340 0a7b8d1a207abc9b237887b944d34c72 370 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 2 343 8.3E-129 T 13-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 Gene3D G3DSA:3.40.5.10 1 50 5.5E-23 T 13-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 Gene3D G3DSA:3.10.430.100 61 149 8.4E-29 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 SUPERFAMILY SSF55658 1 57 6.1E-18 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.9E-20 T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 SUPERFAMILY SSF55653 60 148 2.75E-24 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.146 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 8.1E-24 T 13-10-2018 IPR020069 Ribosomal protein L9, C-terminal MADE_1018940 435d3d8aeefac477f22b76367dac9d60 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 1.1E-52 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001021150 41cb7f4f81b312b97c550a806def4757 113 Gene3D G3DSA:3.30.450.40 1 110 3.4E-10 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_000001021150 41cb7f4f81b312b97c550a806def4757 113 Pfam PF01590 GAF domain 17 101 2.6E-5 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_000001021150 41cb7f4f81b312b97c550a806def4757 113 SUPERFAMILY SSF55781 3 107 3.92E-16 T 13-10-2018 MADE_000001023650 197345df882a6060c5183650adbb3b42 90 SUPERFAMILY SSF103473 9 74 1.83E-5 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_000001023650 197345df882a6060c5183650adbb3b42 90 Gene3D G3DSA:1.20.1250.20 1 81 2.4E-11 T 13-10-2018 MADE_1008010 236001056c051a0b89828acff2be650c 121 Pfam PF05899 Protein of unknown function (DUF861) 52 91 2.9E-5 T 13-10-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 MADE_1008010 236001056c051a0b89828acff2be650c 121 Gene3D G3DSA:2.60.120.10 33 98 1.7E-6 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1008010 236001056c051a0b89828acff2be650c 121 SUPERFAMILY SSF51182 19 105 2.79E-8 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1008680 cc549d32bc9d67ca486043d197e309fa 56 SUPERFAMILY SSF57829 2 54 1.4E-18 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 MADE_1008680 cc549d32bc9d67ca486043d197e309fa 56 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 8.7E-20 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008680 cc549d32bc9d67ca486043d197e309fa 56 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.639 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1008680 cc549d32bc9d67ca486043d197e309fa 56 Pfam PF01783 Ribosomal L32p protein family 2 55 9.7E-20 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1004245 6994b2011421a70870fb2044990064b0 85 Pfam PF01722 BolA-like protein 12 71 1.3E-15 T 13-10-2018 IPR002634 BolA protein MADE_1004245 6994b2011421a70870fb2044990064b0 85 PIRSF PIRSF003113 1 85 7.4E-23 T 13-10-2018 IPR002634 BolA protein MADE_1004245 6994b2011421a70870fb2044990064b0 85 SUPERFAMILY SSF82657 2 80 2.62E-27 T 13-10-2018 IPR036065 BolA-like superfamily MADE_1004245 6994b2011421a70870fb2044990064b0 85 Gene3D G3DSA:3.30.300.90 1 84 3.1E-30 T 13-10-2018 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 488 83.089 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 PIRSF PIRSF000130 1 489 1.4E-199 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 SUPERFAMILY SSF51412 1 479 4.19E-128 T 13-10-2018 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 295 307 - T 13-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 SMART SM00116 96 144 5.9E-8 T 13-10-2018 IPR000644 CBS domain MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 SMART SM00116 158 206 2.4E-6 T 13-10-2018 IPR000644 CBS domain MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 475 2.3E-162 T 13-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 SUPERFAMILY SSF54631 95 203 2.78E-27 T 13-10-2018 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 Gene3D G3DSA:3.20.20.70 1 488 7.7E-209 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 456 2.1E-190 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 Pfam PF00571 CBS domain 158 202 4.7E-5 T 13-10-2018 IPR000644 CBS domain MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 Pfam PF00571 CBS domain 95 140 6.9E-10 T 13-10-2018 IPR000644 CBS domain MADE_1005255 ef39179b1b7b89bc942f45522161f154 489 SMART SM01240 7 475 0.0 T 13-10-2018 MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 SUPERFAMILY SSF46785 3 140 1.21E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 Pfam PF12802 MarR family 30 94 4.2E-10 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 8.6E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 8.6E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 8.6E-7 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 Gene3D G3DSA:1.10.10.10 1 141 2.8E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 SMART SM00347 24 130 1.8E-8 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 MADE_1007830 86eab03498636a28b413bc72f12f37e3 142 ProSitePatterns PS01117 MarR-type HTH domain signature. 69 103 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site MADE_1000860 97b06f62a184af9d98d8330b9a099668 544 Pfam PF01609 Transposase DDE domain 146 466 6.6E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1000860 97b06f62a184af9d98d8330b9a099668 544 Pfam PF14104 Domain of unknown function (DUF4277) 12 117 1.7E-41 T 13-10-2018 IPR025457 Domain of unknown function DUF4277 MADE_1000860 97b06f62a184af9d98d8330b9a099668 544 SUPERFAMILY SSF53098 173 504 1.59E-7 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1005830 97b06f62a184af9d98d8330b9a099668 544 Pfam PF01609 Transposase DDE domain 146 466 6.6E-12 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1005830 97b06f62a184af9d98d8330b9a099668 544 Pfam PF14104 Domain of unknown function (DUF4277) 12 117 1.7E-41 T 13-10-2018 IPR025457 Domain of unknown function DUF4277 MADE_1005830 97b06f62a184af9d98d8330b9a099668 544 SUPERFAMILY SSF53098 173 504 1.59E-7 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 Gene3D G3DSA:1.20.1260.30 1 160 5.6E-28 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 159 175 1.2E-17 T 13-10-2018 MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 326 350 1.2E-17 T 13-10-2018 MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 272 284 1.2E-17 T 13-10-2018 MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 187 201 1.2E-17 T 13-10-2018 MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 Pfam PF02384 N-6 DNA Methylase 137 514 3.5E-56 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 Pfam PF12161 HsdM N-terminal domain 6 127 7.2E-13 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 275 281 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1016850 45079a18efbf4267ead550b180db4ce6 548 SUPERFAMILY SSF53335 5 548 1.82E-113 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1001045 7a13171b85bda9e27bbfb24a50fb1045 210 Pfam PF02441 Flavoprotein 5 181 1.8E-24 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 MADE_1001045 7a13171b85bda9e27bbfb24a50fb1045 210 SUPERFAMILY SSF52507 5 201 3.53E-57 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MADE_1001045 7a13171b85bda9e27bbfb24a50fb1045 210 Gene3D G3DSA:3.40.50.1950 1 203 2.9E-78 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 MADE_1001045 7a13171b85bda9e27bbfb24a50fb1045 210 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 7 200 1.2E-57 T 13-10-2018 IPR004507 Flavin prenyltransferase UbiX-like MADE_1001045 7a13171b85bda9e27bbfb24a50fb1045 210 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 5 202 34.389 T 13-10-2018 IPR004507 Flavin prenyltransferase UbiX-like MADE_1006300 f3b44142672ad1bd5fa37cd4496554ec 87 Pfam PF07615 YKOF-related Family 5 67 4.7E-5 T 13-10-2018 IPR011522 Thiamin/hydroxymethyl pyrimidine-binding YkoF, putative MADE_1006300 f3b44142672ad1bd5fa37cd4496554ec 87 Gene3D G3DSA:3.30.70.930 1 77 1.4E-12 T 13-10-2018 IPR029756 MTH1187/YkoF-like MADE_1006300 f3b44142672ad1bd5fa37cd4496554ec 87 SUPERFAMILY SSF89957 1 80 2.51E-18 T 13-10-2018 IPR029756 MTH1187/YkoF-like MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 SUPERFAMILY SSF54211 568 760 1.37E-33 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 Gene3D G3DSA:3.30.230.10 546 781 2.2E-90 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 Pfam PF13654 AAA domain 36 543 7.7E-169 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 SUPERFAMILY SSF52540 37 541 5.84E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 650 669 2.2E-11 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 710 728 2.2E-11 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 569 585 2.2E-11 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 65 84 2.2E-11 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 680 699 2.2E-11 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 Gene3D G3DSA:3.40.50.300 241 456 1.5E-54 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 Gene3D G3DSA:3.40.50.300 9 171 3.2E-26 T 13-10-2018 MADE_000001021855 9c07a2754f423a72a890ee537e5f83a9 798 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 653 759 9.4E-11 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 MADE_1007295 aab21b9054d4cfeaebef7a872126e4ee 447 Pfam PF01474 Class-II DAHP synthetase family 4 441 2.4E-205 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MADE_1007295 aab21b9054d4cfeaebef7a872126e4ee 447 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 4 446 7.6E-214 T 13-10-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 MADE_1007295 aab21b9054d4cfeaebef7a872126e4ee 447 SUPERFAMILY SSF51569 3 445 6.52E-200 T 13-10-2018 MADE_1008500 a66d575f28783d8c1847cb2217abd50d 738 SUPERFAMILY SSF50956 103 402 2.35E-20 T 13-10-2018 MADE_1008500 a66d575f28783d8c1847cb2217abd50d 738 Pfam PF02333 Phytase 401 730 9.3E-62 T 13-10-2018 IPR003431 Beta propeller phytase GO:0016158 KEGG: 00562+3.1.3.8|MetaCyc: PWY-4702 MADE_1008500 a66d575f28783d8c1847cb2217abd50d 738 SUPERFAMILY SSF50956 402 729 2.48E-66 T 13-10-2018 MADE_1008500 a66d575f28783d8c1847cb2217abd50d 738 Gene3D G3DSA:2.120.10.30 400 738 1.0E-103 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1008500 a66d575f28783d8c1847cb2217abd50d 738 Gene3D G3DSA:2.120.10.30 71 300 3.4E-9 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 SMART SM00487 20 223 2.8E-51 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 SMART SM00490 260 341 2.1E-29 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 Gene3D G3DSA:3.40.50.300 215 424 4.5E-46 T 13-10-2018 MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 Pfam PF00271 Helicase conserved C-terminal domain 235 341 1.8E-27 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 SUPERFAMILY SSF52540 73 356 1.06E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 Pfam PF00270 DEAD/DEAH box helicase 25 190 5.2E-45 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 Gene3D G3DSA:3.40.50.300 2 212 9.2E-66 T 13-10-2018 MADE_1009825 f14258ed13396b77b4e4f25b9fef6a69 441 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site MADE_1010860 510f8538ff6db60ee60421d0eaf172dc 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 196 1.2E-46 T 13-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 MADE_1010860 510f8538ff6db60ee60421d0eaf172dc 200 Gene3D G3DSA:3.40.50.360 2 200 8.8E-59 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1010860 510f8538ff6db60ee60421d0eaf172dc 200 SUPERFAMILY SSF52218 4 197 4.72E-55 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1010860 510f8538ff6db60ee60421d0eaf172dc 200 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 MADE_1010860 510f8538ff6db60ee60421d0eaf172dc 200 Pfam PF03358 NADPH-dependent FMN reductase 11 137 4.4E-8 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MADE_1014310 e71fefa5ae037bf17fb313c99c180d80 392 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 45 359 1.7E-132 T 13-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC MADE_1014310 e71fefa5ae037bf17fb313c99c180d80 392 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 348 1.3E-41 T 13-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 MADE_1018515 f45c286778813cd654ed11d8ea4bc166 561 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 389 509 9.1E-33 T 13-10-2018 IPR025299 CstA, C-terminal domain MADE_1018515 f45c286778813cd654ed11d8ea4bc166 561 Pfam PF02554 Carbon starvation protein CstA 1 361 2.1E-114 T 13-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 MADE_000001020845 13223679c1b26e7b2886b72856540a20 245 Gene3D G3DSA:3.40.1160.10 4 244 8.1E-77 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_000001020845 13223679c1b26e7b2886b72856540a20 245 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 239 3.2E-102 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MADE_000001020845 13223679c1b26e7b2886b72856540a20 245 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.975 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 MADE_000001020845 13223679c1b26e7b2886b72856540a20 245 Pfam PF00696 Amino acid kinase family 11 219 6.7E-28 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MADE_000001020845 13223679c1b26e7b2886b72856540a20 245 PIRSF PIRSF005650 4 245 6.8E-90 T 13-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 MADE_000001020845 13223679c1b26e7b2886b72856540a20 245 SUPERFAMILY SSF53633 8 240 4.84E-73 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1007210 cdd32e7aa2479db9adf7cf599e1a0a39 206 Gene3D G3DSA:2.30.110.10 13 206 1.2E-57 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_1007210 cdd32e7aa2479db9adf7cf599e1a0a39 206 SUPERFAMILY SSF50475 2 196 1.03E-48 T 13-10-2018 MADE_1007210 cdd32e7aa2479db9adf7cf599e1a0a39 206 Pfam PF01613 Flavin reductase like domain 26 169 4.0E-20 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MADE_1007210 cdd32e7aa2479db9adf7cf599e1a0a39 206 SMART SM00903 22 176 1.4E-9 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MADE_1016255 b851fc037b85bb4e70956619955abeee 318 SUPERFAMILY SSF53807 44 298 1.84E-37 T 13-10-2018 MADE_1016255 b851fc037b85bb4e70956619955abeee 318 Gene3D G3DSA:3.40.50.1980 39 160 1.3E-31 T 13-10-2018 MADE_1016255 b851fc037b85bb4e70956619955abeee 318 Pfam PF01497 Periplasmic binding protein 45 270 4.3E-27 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain MADE_1016255 b851fc037b85bb4e70956619955abeee 318 Gene3D G3DSA:3.40.50.1980 161 314 7.0E-24 T 13-10-2018 MADE_1020550 f6b717b6426c24115830bc1d6d42ddd5 89 Pfam PF01809 Haemolytic domain 17 79 3.3E-29 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MADE_1020550 f6b717b6426c24115830bc1d6d42ddd5 89 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 27 79 5.0E-19 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MADE_1020550 f6b717b6426c24115830bc1d6d42ddd5 89 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 8 80 23.649 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MADE_1020550 f6b717b6426c24115830bc1d6d42ddd5 89 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 17 88 1.4E-33 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MADE_1020550 f6b717b6426c24115830bc1d6d42ddd5 89 SMART SM01234 12 79 4.1E-39 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor MADE_000001022755 723349a99dc766086325f06f2f212bb4 471 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 32 116 1.2E-13 T 13-10-2018 IPR026588 Choice-of-anchor A domain MADE_000001022755 723349a99dc766086325f06f2f212bb4 471 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 131 416 2.4E-21 T 13-10-2018 IPR026588 Choice-of-anchor A domain MADE_1007450 662e6a0c0b3e1030061231857a811545 81 Gene3D G3DSA:3.40.50.620 1 81 9.7E-11 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1007450 662e6a0c0b3e1030061231857a811545 81 SUPERFAMILY SSF52374 4 79 2.49E-5 T 13-10-2018 MADE_1013225 1630fba9b190e2df01855eeda6abe84c 281 Pfam PF01226 Formate/nitrite transporter 39 272 3.1E-33 T 13-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 MADE_1013225 1630fba9b190e2df01855eeda6abe84c 281 Gene3D G3DSA:1.20.1080.10 29 279 4.8E-29 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MADE_1020490 f6ba40ec3d8b2a837eebb07f2301fe50 135 Pfam PF03899 ATP synthase I chain 24 117 3.5E-15 T 13-10-2018 IPR005598 ATP synthase protein I MADE_1018145 752f9da16f536152e78c31e482524448 542 Pfam PF03109 ABC1 family 114 229 6.8E-33 T 13-10-2018 IPR004147 UbiB domain MADE_1018145 752f9da16f536152e78c31e482524448 542 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 1 538 52.569 T 13-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 MADE_1018145 752f9da16f536152e78c31e482524448 542 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 4 443 5.9E-174 T 13-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 MADE_1018145 752f9da16f536152e78c31e482524448 542 SUPERFAMILY SSF56112 91 435 2.01E-50 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_000001023605 8d8741c8a256055d7be9b1a28367a721 157 SUPERFAMILY SSF46785 9 141 4.72E-34 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001023605 8d8741c8a256055d7be9b1a28367a721 157 Gene3D G3DSA:3.30.1490.190 89 148 3.7E-18 T 13-10-2018 MADE_000001023605 8d8741c8a256055d7be9b1a28367a721 157 Pfam PF01475 Ferric uptake regulator family 17 135 3.0E-19 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 MADE_000001023605 8d8741c8a256055d7be9b1a28367a721 157 Gene3D G3DSA:1.10.10.10 1 86 1.7E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 Gene3D G3DSA:3.30.160.20 212 299 2.3E-98 T 13-10-2018 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 359 1.3E-174 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 Gene3D G3DSA:1.20.58.410 3 104 1.9E-9 T 13-10-2018 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 42.504 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 Pfam PF03462 PCRF domain 13 205 1.5E-78 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 Gene3D G3DSA:3.30.70.1660 113 344 2.3E-98 T 13-10-2018 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 Pfam PF00472 RF-1 domain 215 323 2.1E-43 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 SUPERFAMILY SSF75620 12 355 7.19E-142 T 13-10-2018 MADE_1007645 2bd81f7ae1ee35ceb81107df6822a225 361 SMART SM00937 67 180 3.2E-70 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 MADE_1003735 1a34b05d7e7143f8d454941473002d32 295 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1003735 1a34b05d7e7143f8d454941473002d32 295 Gene3D G3DSA:3.40.50.300 3 294 3.7E-63 T 13-10-2018 MADE_1003735 1a34b05d7e7143f8d454941473002d32 295 SUPERFAMILY SSF52540 6 245 1.02E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003735 1a34b05d7e7143f8d454941473002d32 295 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 25 254 1.8E-104 T 13-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 MADE_1003735 1a34b05d7e7143f8d454941473002d32 295 Pfam PF00005 ABC transporter 25 166 1.1E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1003735 1a34b05d7e7143f8d454941473002d32 295 SMART SM00382 34 216 1.4E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005485 ee52b5bdcc17cbb75136fc33ee0f067a 218 Gene3D G3DSA:3.30.1330.60 82 215 2.5E-33 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1005485 ee52b5bdcc17cbb75136fc33ee0f067a 218 SUPERFAMILY SSF103088 94 210 1.7E-30 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1005485 ee52b5bdcc17cbb75136fc33ee0f067a 218 Pfam PF00691 OmpA family 110 205 1.4E-20 T 13-10-2018 IPR006665 OmpA-like domain MADE_1005485 ee52b5bdcc17cbb75136fc33ee0f067a 218 PRINTS PR01021 OMPA domain signature 140 155 3.4E-9 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1005485 ee52b5bdcc17cbb75136fc33ee0f067a 218 PRINTS PR01021 OMPA domain signature 155 171 3.4E-9 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1005485 ee52b5bdcc17cbb75136fc33ee0f067a 218 PRINTS PR01021 OMPA domain signature 110 132 3.4E-9 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 PIRSF PIRSF006431 1 320 1.9E-106 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 8.2E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 8.2E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 8.2E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 SUPERFAMILY SSF53474 5 300 5.67E-51 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 Pfam PF00561 alpha/beta hydrolase fold 36 299 1.1E-25 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 Gene3D G3DSA:3.40.50.1820 1 317 2.2E-82 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1018345 88bda7f5851cbbd50af160a908f2e0bc 325 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 316 1.2E-98 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 MADE_1009565 631019d1571fe1cbab904a1e5f560d2f 493 Pfam PF13347 MFS/sugar transport protein 42 220 1.4E-17 T 13-10-2018 MADE_1009565 631019d1571fe1cbab904a1e5f560d2f 493 SUPERFAMILY SSF103473 11 484 1.57E-39 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1009565 631019d1571fe1cbab904a1e5f560d2f 493 ProSitePatterns PS00216 Sugar transport proteins signature 1. 339 355 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MADE_1009565 631019d1571fe1cbab904a1e5f560d2f 493 Gene3D G3DSA:1.20.1250.20 10 218 1.0E-17 T 13-10-2018 MADE_1009565 631019d1571fe1cbab904a1e5f560d2f 493 Pfam PF07690 Major Facilitator Superfamily 302 484 1.8E-12 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1009565 631019d1571fe1cbab904a1e5f560d2f 493 Gene3D G3DSA:1.20.1250.20 295 493 9.1E-17 T 13-10-2018 MADE_1010165 ff80d7ec6e6678f45a2cdef5baf2d5ff 1612 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 76 1604 0.0 T 13-10-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 MADE_1010165 ff80d7ec6e6678f45a2cdef5baf2d5ff 1612 SUPERFAMILY SSF53223 757 944 2.4E-23 T 13-10-2018 MADE_1010165 ff80d7ec6e6678f45a2cdef5baf2d5ff 1612 PIRSF PIRSF036761 1 1611 0.0 T 13-10-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 MADE_1010165 ff80d7ec6e6678f45a2cdef5baf2d5ff 1612 SUPERFAMILY SSF51735 948 1235 1.44E-30 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1019325 4f10de629a3bddb28c16e258102bc955 154 SUPERFAMILY SSF54690 2 147 2.62E-47 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MADE_1019325 4f10de629a3bddb28c16e258102bc955 154 Pfam PF02391 MoaE protein 9 117 1.6E-34 T 13-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MADE_1019325 4f10de629a3bddb28c16e258102bc955 154 Gene3D G3DSA:3.90.1170.40 1 147 4.2E-49 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MADE_1010970 be9fd2d09e09a14233dc0d3f5b284a6d 321 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 30 48 - T 13-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 MADE_1010970 be9fd2d09e09a14233dc0d3f5b284a6d 321 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 310 2.9E-132 T 13-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MADE_1010970 be9fd2d09e09a14233dc0d3f5b284a6d 321 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 310 3.0E-139 T 13-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 MADE_1010970 be9fd2d09e09a14233dc0d3f5b284a6d 321 SUPERFAMILY SSF53686 4 308 2.62E-97 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme MADE_1010970 be9fd2d09e09a14233dc0d3f5b284a6d 321 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 296 1.2E-71 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme MADE_1010970 be9fd2d09e09a14233dc0d3f5b284a6d 321 Gene3D G3DSA:3.40.50.1100 42 144 7.2E-124 T 13-10-2018 MADE_1010970 be9fd2d09e09a14233dc0d3f5b284a6d 321 Gene3D G3DSA:3.40.50.1100 11 305 7.2E-124 T 13-10-2018 MADE_1002105 0693c4e5015a802df5584a2f934acbf1 309 Pfam PF01261 Xylose isomerase-like TIM barrel 124 255 1.1E-17 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MADE_1002105 0693c4e5015a802df5584a2f934acbf1 309 Gene3D G3DSA:3.20.20.150 56 303 4.8E-47 T 13-10-2018 MADE_1002105 0693c4e5015a802df5584a2f934acbf1 309 SUPERFAMILY SSF51658 58 296 1.52E-55 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily MADE_1013930 551146c7c40e5085d5316e293b82e36e 133 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.668 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013930 551146c7c40e5085d5316e293b82e36e 133 Gene3D G3DSA:3.90.1030.10 1 117 1.2E-47 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013930 551146c7c40e5085d5316e293b82e36e 133 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 5.9E-49 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013930 551146c7c40e5085d5316e293b82e36e 133 SUPERFAMILY SSF64263 1 119 1.96E-51 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013930 551146c7c40e5085d5316e293b82e36e 133 Pfam PF01196 Ribosomal protein L17 20 116 3.4E-34 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013930 551146c7c40e5085d5316e293b82e36e 133 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013825 f2b50037373219c9bca80b65896e02b3 319 Gene3D G3DSA:3.90.550.10 1 231 3.6E-38 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013825 f2b50037373219c9bca80b65896e02b3 319 Pfam PF00535 Glycosyl transferase family 2 5 131 3.3E-21 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1013825 f2b50037373219c9bca80b65896e02b3 319 SUPERFAMILY SSF53448 4 248 7.97E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1007740 c0763b4f4261b24cdf154fc56e5051b1 263 SUPERFAMILY SSF47598 1 33 3.33E-12 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1007740 c0763b4f4261b24cdf154fc56e5051b1 263 SUPERFAMILY SSF82808 146 256 5.23E-37 T 13-10-2018 IPR036835 Replication modulator SeqA, C-terminal DNA-binding domain superfamily GO:0003677 MADE_1007740 c0763b4f4261b24cdf154fc56e5051b1 263 Pfam PF03925 SeqA protein C-terminal domain 152 255 3.2E-35 T 13-10-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 MADE_1007740 c0763b4f4261b24cdf154fc56e5051b1 263 Gene3D G3DSA:1.20.1380.10 143 257 6.3E-41 T 13-10-2018 IPR036835 Replication modulator SeqA, C-terminal DNA-binding domain superfamily GO:0003677 MADE_1007740 c0763b4f4261b24cdf154fc56e5051b1 263 Pfam PF17206 SeqA protein N-terminal domain 1 33 1.2E-20 T 13-10-2018 IPR033761 Negative modulator of initiation of replication SeqA, N-terminal MADE_1007740 c0763b4f4261b24cdf154fc56e5051b1 263 Gene3D G3DSA:1.10.1220.10 1 38 4.7E-22 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 27 312 9.0E-127 T 13-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 SUPERFAMILY SSF53335 39 284 2.54E-48 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 222 228 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 20 318 49.976 T 13-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 Gene3D G3DSA:1.10.8.10 29 124 1.6E-7 T 13-10-2018 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 29 319 3.7E-86 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 PIRSF PIRSF037167 12 324 8.8E-134 T 13-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 Pfam PF05175 Methyltransferase small domain 150 233 1.7E-15 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 MADE_1006525 1c1a3dad044019d585c50c67aa85ab2f 324 Gene3D G3DSA:3.40.50.150 127 297 4.4E-46 T 13-10-2018 MADE_1008275 645db4a9551be4c6add56a20e2a17d86 326 Pfam PF01409 tRNA synthetases class II core domain (F) 91 325 5.0E-106 T 13-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 MADE_1008275 645db4a9551be4c6add56a20e2a17d86 326 Gene3D G3DSA:3.30.930.10 6 326 2.7E-126 T 13-10-2018 MADE_1008275 645db4a9551be4c6add56a20e2a17d86 326 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 19 86 3.9E-24 T 13-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MADE_1008275 645db4a9551be4c6add56a20e2a17d86 326 SUPERFAMILY SSF46589 13 98 1.36E-21 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MADE_1008275 645db4a9551be4c6add56a20e2a17d86 326 SUPERFAMILY SSF55681 91 326 8.16E-84 T 13-10-2018 MADE_1008275 645db4a9551be4c6add56a20e2a17d86 326 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 163 325 5.3E-81 T 13-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 MADE_1008275 645db4a9551be4c6add56a20e2a17d86 326 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 7 325 48.5 T 13-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 MADE_1016555 7988c0afcb8bca619477dfcec421384d 148 PIRSF PIRSF004638 1 141 3.3E-15 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 MADE_1016555 7988c0afcb8bca619477dfcec421384d 148 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 115 1.2E-12 T 13-10-2018 IPR005265 Uncharacterised protein family UPF0093 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 1.2E-13 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 512 2.3E-254 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 SUPERFAMILY SSF52540 96 381 3.25E-94 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 SUPERFAMILY SSF47917 383 511 1.2E-45 T 13-10-2018 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 Gene3D G3DSA:3.40.50.300 94 382 5.0E-131 T 13-10-2018 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.9E-44 T 13-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 Gene3D G3DSA:2.40.30.20 1 93 3.3E-30 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 Gene3D G3DSA:1.20.150.20 383 513 7.9E-47 T 13-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 3.3E-73 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.133 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 MADE_1020460 fdd63838335c5f22a7e32c4112b740b3 513 SUPERFAMILY SSF50615 10 94 4.32E-26 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 MADE_1004455 7523362b5d2493ff2f0d09a11ad8454d 200 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 13-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site MADE_1004455 7523362b5d2493ff2f0d09a11ad8454d 200 SUPERFAMILY SSF54211 2 130 4.17E-43 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold MADE_1004455 7523362b5d2493ff2f0d09a11ad8454d 200 Pfam PF09186 Domain of unknown function (DUF1949) 140 189 3.2E-7 T 13-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal MADE_1004455 7523362b5d2493ff2f0d09a11ad8454d 200 Pfam PF01205 Uncharacterized protein family UPF0029 17 124 7.4E-32 T 13-10-2018 IPR001498 Impact, N-terminal MADE_1004455 7523362b5d2493ff2f0d09a11ad8454d 200 SUPERFAMILY SSF54980 137 189 5.04E-9 T 13-10-2018 IPR035647 EF-G domain III/V-like MADE_1004455 7523362b5d2493ff2f0d09a11ad8454d 200 Gene3D G3DSA:3.30.230.30 1 133 1.9E-51 T 13-10-2018 IPR036956 Impact, N-terminal domain superfamily MADE_1004455 7523362b5d2493ff2f0d09a11ad8454d 200 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 191 6.2E-57 T 13-10-2018 IPR015796 Impact family, bacterial/archaeal MADE_1010570 78aa53c149360f121929e10fd62d3817 412 Gene3D G3DSA:3.30.160.390 1 101 1.8E-34 T 13-10-2018 IPR038488 Integrase, DNA-binding domain superfamily MADE_1010570 78aa53c149360f121929e10fd62d3817 412 Gene3D G3DSA:1.10.443.10 206 389 2.2E-20 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1010570 78aa53c149360f121929e10fd62d3817 412 Pfam PF13356 Arm DNA-binding domain 3 87 3.8E-18 T 13-10-2018 IPR025166 Integrase, DNA-binding domain MADE_1010570 78aa53c149360f121929e10fd62d3817 412 Gene3D G3DSA:1.10.150.130 102 205 2.7E-27 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal MADE_1010570 78aa53c149360f121929e10fd62d3817 412 SUPERFAMILY SSF56349 100 389 1.29E-57 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1010570 78aa53c149360f121929e10fd62d3817 412 Pfam PF00589 Phage integrase family 210 378 3.6E-24 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1012890 52f59e79dc222891fd71477b4a0d2d31 405 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 7 403 3.5E-164 T 13-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 MADE_1012890 52f59e79dc222891fd71477b4a0d2d31 405 Pfam PF00266 Aminotransferase class-V 25 393 1.1E-141 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_1012890 52f59e79dc222891fd71477b4a0d2d31 405 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216 235 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MADE_1012890 52f59e79dc222891fd71477b4a0d2d31 405 Gene3D G3DSA:3.40.640.10 36 295 2.4E-166 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1012890 52f59e79dc222891fd71477b4a0d2d31 405 SUPERFAMILY SSF53383 4 400 9.85E-121 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1012890 52f59e79dc222891fd71477b4a0d2d31 405 Gene3D G3DSA:3.90.1150.10 9 397 2.4E-166 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1009170 93cd71ab13f2e015fbce32c828eba27f 143 SUPERFAMILY SSF55961 1 143 8.68E-33 T 13-10-2018 MADE_1009170 93cd71ab13f2e015fbce32c828eba27f 143 Gene3D G3DSA:3.30.530.20 3 143 1.0E-37 T 13-10-2018 IPR023393 START-like domain superfamily MADE_1009170 93cd71ab13f2e015fbce32c828eba27f 143 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 135 4.0E-31 T 13-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 MADE_1006920 2a93251b59727a2d58aeaf965e04facb 197 PIRSF PIRSF019345 1 194 6.7E-61 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MADE_1006920 2a93251b59727a2d58aeaf965e04facb 197 Gene3D G3DSA:1.10.10.10 3 85 3.5E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006920 2a93251b59727a2d58aeaf965e04facb 197 Gene3D G3DSA:1.10.10.10 86 183 8.6E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006920 2a93251b59727a2d58aeaf965e04facb 197 Pfam PF04079 Segregation and condensation complex subunit ScpB 12 171 8.3E-53 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MADE_1006920 2a93251b59727a2d58aeaf965e04facb 197 SUPERFAMILY SSF46785 89 162 1.3E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1006920 2a93251b59727a2d58aeaf965e04facb 197 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 9 176 2.6E-33 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 MADE_1006920 2a93251b59727a2d58aeaf965e04facb 197 SUPERFAMILY SSF46785 4 86 4.36E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1019535 33c973772285cbaf2062cf7373e9a9a4 247 Pfam PF07277 SapC 7 227 5.6E-67 T 13-10-2018 IPR010836 SapC MADE_1008405 fc909731aee6557a52e42f5a17ee09f1 177 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 29 174 4.2E-16 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase MADE_1008405 fc909731aee6557a52e42f5a17ee09f1 177 SUPERFAMILY SSF55961 24 175 2.41E-22 T 13-10-2018 MADE_1008405 fc909731aee6557a52e42f5a17ee09f1 177 Gene3D G3DSA:3.30.530.20 27 176 6.6E-17 T 13-10-2018 IPR023393 START-like domain superfamily MADE_000001022430 4276cb4d499d4a05bcd874856b5169c7 274 Pfam PF03724 META domain 46 152 1.8E-22 T 13-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ MADE_000001022430 4276cb4d499d4a05bcd874856b5169c7 274 SUPERFAMILY SSF141488 195 271 8.89E-15 T 13-10-2018 IPR036328 C-type lysozyme inhibitor superfamily MADE_000001022430 4276cb4d499d4a05bcd874856b5169c7 274 Gene3D G3DSA:2.40.128.270 38 155 1.3E-17 T 13-10-2018 IPR038670 HslJ-like superfamily MADE_000001022430 4276cb4d499d4a05bcd874856b5169c7 274 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 200 268 1.7E-11 T 13-10-2018 IPR018660 C-type lysozyme inhibitor MADE_000001022430 4276cb4d499d4a05bcd874856b5169c7 274 Gene3D G3DSA:2.40.128.200 195 272 4.5E-13 T 13-10-2018 IPR036328 C-type lysozyme inhibitor superfamily MADE_1002080 3de6c97c037ea17675f52c1f988ac8c2 317 Gene3D G3DSA:3.20.20.150 53 313 7.8E-71 T 13-10-2018 MADE_1002080 3de6c97c037ea17675f52c1f988ac8c2 317 Pfam PF01261 Xylose isomerase-like TIM barrel 90 271 1.1E-18 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MADE_1002080 3de6c97c037ea17675f52c1f988ac8c2 317 SUPERFAMILY SSF51658 71 287 9.51E-41 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily MADE_1015570 f9ecac1a1eb5b273baf1419c81bec9ea 337 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 271 277 - T 13-10-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 MADE_1015570 f9ecac1a1eb5b273baf1419c81bec9ea 337 Hamap MF_01962 Adenine deaminase. 4 316 64.81 T 13-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MADE_1015570 f9ecac1a1eb5b273baf1419c81bec9ea 337 Pfam PF00962 Adenosine/AMP deaminase 8 325 5.7E-57 T 13-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 MADE_1015570 f9ecac1a1eb5b273baf1419c81bec9ea 337 SUPERFAMILY SSF51556 3 326 6.47E-71 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1015570 f9ecac1a1eb5b273baf1419c81bec9ea 337 Gene3D G3DSA:3.20.20.140 1 336 3.2E-90 T 13-10-2018 MADE_1015570 f9ecac1a1eb5b273baf1419c81bec9ea 337 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 9 326 2.2E-103 T 13-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 MADE_1012215 58bee7232bd5f8fe01b00cd3044a7a7d 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 8.9E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1012215 58bee7232bd5f8fe01b00cd3044a7a7d 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 8.9E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1012215 58bee7232bd5f8fe01b00cd3044a7a7d 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 8.9E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1012215 58bee7232bd5f8fe01b00cd3044a7a7d 279 Pfam PF00561 alpha/beta hydrolase fold 24 136 8.1E-19 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1012215 58bee7232bd5f8fe01b00cd3044a7a7d 279 SUPERFAMILY SSF53474 7 278 2.16E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1012215 58bee7232bd5f8fe01b00cd3044a7a7d 279 Gene3D G3DSA:3.40.50.1820 5 272 1.3E-49 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1000155 155397599fc4c789f611f548df5ee060 180 SUPERFAMILY SSF51161 7 177 2.22E-42 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1000155 155397599fc4c789f611f548df5ee060 180 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 97 130 9.0E-6 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1000155 155397599fc4c789f611f548df5ee060 180 Gene3D G3DSA:2.160.10.10 1 180 2.5E-51 T 13-10-2018 MADE_1015990 e6c2936532f3009d362729664052a243 208 Pfam PF13511 Domain of unknown function (DUF4124) 53 110 4.1E-5 T 13-10-2018 IPR025392 Domain of unknown function DUF4124 MADE_1012490 fbbcbbdc5053e567ebb309585d5b5f7a 327 Gene3D G3DSA:3.40.50.1000 33 327 4.9E-73 T 13-10-2018 IPR023214 HAD superfamily MADE_1012490 fbbcbbdc5053e567ebb309585d5b5f7a 327 SUPERFAMILY SSF56784 120 326 7.46E-48 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1012490 fbbcbbdc5053e567ebb309585d5b5f7a 327 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 110 324 2.6E-76 T 13-10-2018 MADE_1012490 fbbcbbdc5053e567ebb309585d5b5f7a 327 Pfam PF00702 haloacid dehalogenase-like hydrolase 122 292 5.9E-15 T 13-10-2018 MADE_1012490 fbbcbbdc5053e567ebb309585d5b5f7a 327 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 122 292 6.4E-29 T 13-10-2018 MADE_1008615 2087135a979196d2b1ba104aab689244 183 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 3 183 4.4E-57 T 13-10-2018 IPR018636 Protein of unknown function DUF2058 MADE_1011740 24ab10d24abb017cadb78e6e8ef1d5bd 325 Gene3D G3DSA:3.60.10.10 102 323 5.2E-21 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1011740 24ab10d24abb017cadb78e6e8ef1d5bd 325 SUPERFAMILY SSF56219 104 320 6.02E-28 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1011740 24ab10d24abb017cadb78e6e8ef1d5bd 325 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 110 313 7.9E-14 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 SUPERFAMILY SSF63411 233 467 1.75E-63 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Gene3D G3DSA:3.30.830.10 4 231 3.6E-67 T 13-10-2018 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Pfam PF16187 Middle or third domain of peptidase_M16 366 641 1.4E-52 T 13-10-2018 IPR032632 Peptidase M16, middle/third domain MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Pfam PF00675 Insulinase (Peptidase family M16) 23 154 2.5E-29 T 13-10-2018 IPR011765 Peptidase M16, N-terminal MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 SUPERFAMILY SSF63411 701 915 1.12E-39 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 SUPERFAMILY SSF63411 468 686 3.48E-42 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Pfam PF05193 Peptidase M16 inactive domain 183 354 1.0E-15 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Pfam PF05193 Peptidase M16 inactive domain 645 783 6.2E-7 T 13-10-2018 IPR007863 Peptidase M16, C-terminal MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Gene3D G3DSA:3.30.830.10 237 466 7.5E-60 T 13-10-2018 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 SUPERFAMILY SSF63411 11 226 1.52E-44 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Gene3D G3DSA:3.30.830.10 616 874 2.0E-91 T 13-10-2018 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 41 64 - T 13-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 MADE_000001020955 7e1bc806c829c15c0dc8584f1f89c1f4 915 Gene3D G3DSA:3.30.830.10 468 847 2.0E-91 T 13-10-2018 MADE_1002460 7d14c9cd0defe3e0205d2eda4f42430e 379 Gene3D G3DSA:1.10.287.470 109 177 3.0E-51 T 13-10-2018 MADE_1002460 7d14c9cd0defe3e0205d2eda4f42430e 379 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 74 284 1.4E-15 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain MADE_1002460 7d14c9cd0defe3e0205d2eda4f42430e 379 Gene3D G3DSA:2.40.30.170 63 290 3.0E-51 T 13-10-2018 MADE_1002460 7d14c9cd0defe3e0205d2eda4f42430e 379 Gene3D G3DSA:2.40.420.20 291 368 3.0E-51 T 13-10-2018 MADE_1002460 7d14c9cd0defe3e0205d2eda4f42430e 379 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 65 370 2.8E-54 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 MADE_1002460 7d14c9cd0defe3e0205d2eda4f42430e 379 SUPERFAMILY SSF111369 66 234 1.96E-19 T 13-10-2018 MADE_1002460 7d14c9cd0defe3e0205d2eda4f42430e 379 Gene3D G3DSA:2.40.50.100 75 221 3.0E-51 T 13-10-2018 MADE_000001022800 8699858d6e1728954c514097446f0058 737 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 126 445 3.6E-99 T 13-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 MADE_000001022800 8699858d6e1728954c514097446f0058 737 Pfam PF00326 Prolyl oligopeptidase family 541 736 3.7E-54 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MADE_000001022800 8699858d6e1728954c514097446f0058 737 SUPERFAMILY SSF53474 482 736 1.46E-74 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001022800 8699858d6e1728954c514097446f0058 737 SUPERFAMILY SSF82171 19 466 3.01E-66 T 13-10-2018 MADE_000001022800 8699858d6e1728954c514097446f0058 737 Gene3D G3DSA:3.40.50.1820 486 736 1.6E-76 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001022800 8699858d6e1728954c514097446f0058 737 Gene3D G3DSA:2.140.10.30 20 476 1.0E-165 T 13-10-2018 IPR038554 Dipeptidylpeptidase IV, N-terminal domain superfamily MADE_1019715 fc3ba9ba732ca39b08b8ed7589011340 544 Pfam PF01425 Amidase 57 505 5.3E-97 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MADE_1019715 fc3ba9ba732ca39b08b8ed7589011340 544 Gene3D G3DSA:3.90.1300.10 10 521 5.3E-158 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MADE_1019715 fc3ba9ba732ca39b08b8ed7589011340 544 SUPERFAMILY SSF75304 36 521 2.35E-115 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 MADE_1005775 9fe3a78103879ee34d04bbef08d65029 171 Gene3D G3DSA:3.30.160.170 54 150 7.7E-13 T 13-10-2018 IPR035924 FlaG-like superfamily MADE_1005775 9fe3a78103879ee34d04bbef08d65029 171 Pfam PF03646 FlaG protein 64 169 6.8E-17 T 13-10-2018 IPR005186 FlaG protein MADE_1005775 9fe3a78103879ee34d04bbef08d65029 171 SUPERFAMILY SSF160214 67 169 9.02E-17 T 13-10-2018 IPR035924 FlaG-like superfamily MADE_1011795 f841cef459c5ad6993d837e232a1d21f 199 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 174 196 0.0031 T 13-10-2018 IPR013424 PEP-CTERM protein-sorting domain MADE_1012370 20231a4236bf91bc0fcaff8ca031266e 146 SUPERFAMILY SSF54427 4 122 7.26E-15 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1012370 20231a4236bf91bc0fcaff8ca031266e 146 Gene3D G3DSA:3.10.450.50 3 131 4.4E-15 T 13-10-2018 MADE_1012370 20231a4236bf91bc0fcaff8ca031266e 146 Pfam PF10184 Uncharacterized conserved protein (DUF2358) 23 115 3.6E-7 T 13-10-2018 IPR018790 Protein of unknown function DUF2358 MADE_000001022670 f08bbef9ba9aee7b464fdb88c2e4bd61 381 Pfam PF07715 TonB-dependent Receptor Plug Domain 97 203 3.0E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_000001022670 f08bbef9ba9aee7b464fdb88c2e4bd61 381 Gene3D G3DSA:2.170.130.10 54 209 1.5E-10 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_000001022670 f08bbef9ba9aee7b464fdb88c2e4bd61 381 SUPERFAMILY SSF56935 58 374 2.82E-21 T 13-10-2018 MADE_1002260 7a842c6524f0ec1ce80d308789bc29d7 212 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 40.195 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002260 7a842c6524f0ec1ce80d308789bc29d7 212 Gene3D G3DSA:2.40.30.10 133 212 1.5E-17 T 13-10-2018 MADE_1002260 7a842c6524f0ec1ce80d308789bc29d7 212 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 207 2.7E-90 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002260 7a842c6524f0ec1ce80d308789bc29d7 212 SUPERFAMILY SSF50447 2 211 2.83E-81 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily MADE_1002260 7a842c6524f0ec1ce80d308789bc29d7 212 Gene3D G3DSA:2.40.50.620 33 99 4.6E-16 T 13-10-2018 MADE_1002260 7a842c6524f0ec1ce80d308789bc29d7 212 Pfam PF00297 Ribosomal protein L3 46 185 1.2E-15 T 13-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002260 7a842c6524f0ec1ce80d308789bc29d7 212 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 13-10-2018 IPR019926 Ribosomal protein L3, conserved site MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 4.8E-71 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 5.6E-48 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 5.6E-48 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 5.6E-48 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 5.6E-48 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 5.6E-48 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 Gene3D G3DSA:3.30.360.10 149 314 2.5E-157 T 13-10-2018 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 1.2E-139 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 8.6E-42 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 SMART SM00846 3 150 9.1E-99 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 SUPERFAMILY SSF55347 149 312 3.74E-80 T 13-10-2018 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 PIRSF PIRSF000149 1 331 2.2E-135 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 SUPERFAMILY SSF51735 3 166 2.83E-69 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1011675 b2f382b87521dcdf29a93ed7adf058ae 331 Gene3D G3DSA:3.40.50.720 4 326 2.5E-157 T 13-10-2018 MADE_1013945 7f86084f41014dcdbe3aa99cdff43b52 130 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 11 127 1.4E-54 T 13-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1013945 7f86084f41014dcdbe3aa99cdff43b52 130 SUPERFAMILY SSF53137 18 130 3.6E-47 T 13-10-2018 MADE_1013945 7f86084f41014dcdbe3aa99cdff43b52 130 PIRSF PIRSF002131 1 130 8.1E-52 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MADE_1013945 7f86084f41014dcdbe3aa99cdff43b52 130 Pfam PF00411 Ribosomal protein S11 20 129 2.2E-50 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MADE_1013945 7f86084f41014dcdbe3aa99cdff43b52 130 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 130 32.74 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 MADE_1013945 7f86084f41014dcdbe3aa99cdff43b52 130 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 13-10-2018 IPR018102 Ribosomal S11, conserved site MADE_1013945 7f86084f41014dcdbe3aa99cdff43b52 130 Gene3D G3DSA:3.30.420.80 1 130 4.5E-56 T 13-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1010910 ebbf17e18680ee7881b4b8d7fac4a921 243 Gene3D G3DSA:3.40.50.150 18 243 1.1E-56 T 13-10-2018 MADE_1010910 ebbf17e18680ee7881b4b8d7fac4a921 243 SUPERFAMILY SSF53335 19 242 9.21E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1010910 ebbf17e18680ee7881b4b8d7fac4a921 243 PIRSF PIRSF006325 1 243 4.1E-99 T 13-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MADE_1010910 ebbf17e18680ee7881b4b8d7fac4a921 243 Pfam PF13649 Methyltransferase domain 60 158 1.1E-11 T 13-10-2018 MADE_1010910 ebbf17e18680ee7881b4b8d7fac4a921 243 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 3 242 39.067 T 13-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MADE_1010910 ebbf17e18680ee7881b4b8d7fac4a921 243 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 5 242 1.0E-94 T 13-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 MADE_1000600 7fc152cace2ca0995844ee891fbd0ac9 622 TIGRFAM TIGR04096 dnd_rel_methyl: DNA phosphorothioation-associated putative methyltransferase 182 622 9.7E-165 T 13-10-2018 IPR024019 Conserved hypothetical protein CHP04096 MADE_1000600 7fc152cace2ca0995844ee891fbd0ac9 622 Gene3D G3DSA:3.40.50.150 182 393 1.6E-5 T 13-10-2018 MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 Gene3D G3DSA:2.60.40.10 39 126 8.2E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 SUPERFAMILY SSF51445 142 553 2.27E-97 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 SMART SM00642 146 544 1.0E-65 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 Gene3D G3DSA:3.20.20.80 134 553 6.6E-136 T 13-10-2018 MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 SUPERFAMILY SSF81296 41 130 3.78E-24 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 Gene3D G3DSA:2.60.40.1180 554 643 3.0E-9 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 SUPERFAMILY SSF51011 554 640 3.38E-5 T 13-10-2018 MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 Pfam PF09087 Cyclomaltodextrinase, N-terminal 44 129 3.0E-25 T 13-10-2018 IPR015171 Cyclomaltodextrinase, N-terminal MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 Pfam PF00128 Alpha amylase, catalytic domain 180 496 1.1E-52 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1009560 89a9cabf2bdcadeca6d3aa8d66a1dd2b 644 Pfam PF10438 Cyclo-malto-dextrinase C-terminal domain 555 641 1.9E-19 T 13-10-2018 IPR019492 Cyclo-malto-dextrinase, C-terminal MADE_000001022025 4318fc462e62fd921659b83ab2a9b37c 58 Hamap MF_00919 Ribosome modulation factor [rmf]. 1 55 31.344 T 13-10-2018 IPR007040 Ribosome modulation factor MADE_000001022025 4318fc462e62fd921659b83ab2a9b37c 58 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 51 1.0E-17 T 13-10-2018 IPR007040 Ribosome modulation factor MADE_000001022025 4318fc462e62fd921659b83ab2a9b37c 58 Pfam PF04957 Ribosome modulation factor 1 54 1.1E-29 T 13-10-2018 IPR007040 Ribosome modulation factor MADE_000001022025 4318fc462e62fd921659b83ab2a9b37c 58 Gene3D G3DSA:1.10.10.620 1 56 4.2E-28 T 13-10-2018 IPR023200 Ribosome modulation factor domain superfamily MADE_1006305 7e53dc7d12f33a76fc89c7026f30d438 214 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 16 198 4.7E-13 T 13-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MADE_1006305 7e53dc7d12f33a76fc89c7026f30d438 214 Pfam PF04973 Nicotinamide mononucleotide transporter 16 194 1.2E-36 T 13-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 MADE_1002095 3328a9067cbc4bb759d32929e716f95a 355 Pfam PF07582 AP endonuclease family 2 C terminus 283 337 3.0E-21 T 13-10-2018 IPR011418 AP endonuclease, family 2, C-terminal MADE_1002095 3328a9067cbc4bb759d32929e716f95a 355 SUPERFAMILY SSF51658 12 326 1.66E-66 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily MADE_1002095 3328a9067cbc4bb759d32929e716f95a 355 Gene3D G3DSA:3.20.20.150 21 329 9.8E-76 T 13-10-2018 MADE_1002095 3328a9067cbc4bb759d32929e716f95a 355 Pfam PF01261 Xylose isomerase-like TIM barrel 33 282 1.0E-41 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain MADE_1007145 a76df2f406f14740726a13778d3fece4 158 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 13-10-2018 IPR020549 Endoribonuclease YbeY, conserved site MADE_1007145 a76df2f406f14740726a13778d3fece4 158 Gene3D G3DSA:3.40.390.30 2 158 5.6E-53 T 13-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 MADE_1007145 a76df2f406f14740726a13778d3fece4 158 Pfam PF02130 Uncharacterized protein family UPF0054 25 148 1.5E-39 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MADE_1007145 a76df2f406f14740726a13778d3fece4 158 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 152 23.726 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MADE_1007145 a76df2f406f14740726a13778d3fece4 158 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 44 149 1.0E-36 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 MADE_1007145 a76df2f406f14740726a13778d3fece4 158 SUPERFAMILY SSF55486 22 154 9.52E-49 T 13-10-2018 MADE_1004555 8cabe8cf4abf63746040be4adbd60178 308 Gene3D G3DSA:3.90.70.10 54 195 4.0E-14 T 13-10-2018 MADE_1004555 8cabe8cf4abf63746040be4adbd60178 308 Pfam PF13529 Peptidase_C39 like family 48 158 8.4E-9 T 13-10-2018 IPR039564 Peptidase C39-like MADE_1004555 8cabe8cf4abf63746040be4adbd60178 308 SUPERFAMILY SSF48452 200 304 2.28E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1004555 8cabe8cf4abf63746040be4adbd60178 308 Gene3D G3DSA:1.25.40.10 196 306 1.2E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 334 182.993 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 238 2.0E-118 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 Gene3D G3DSA:1.10.8.60 185 258 6.0E-30 T 13-10-2018 MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 Gene3D G3DSA:1.10.10.10 260 334 1.4E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 SUPERFAMILY SSF52540 23 254 5.87E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 330 8.0E-36 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 SUPERFAMILY SSF46785 260 331 1.58E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 SMART SM00382 54 181 1.9E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 26 329 7.2E-148 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 2.5E-34 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 MADE_000001021180 c5c5d9ec002555608bad6ad4ccceff74 334 Gene3D G3DSA:3.40.50.300 23 184 7.4E-40 T 13-10-2018 MADE_1012535 eaf5bcbbedfa9bcd64e686b2f59d37b9 368 Pfam PF17188 MucB/RseB C-terminal domain 269 363 4.8E-23 T 13-10-2018 IPR033436 MucB/RseB, C-terminal MADE_1012535 eaf5bcbbedfa9bcd64e686b2f59d37b9 368 Gene3D G3DSA:3.30.200.100 270 367 1.5E-23 T 13-10-2018 IPR038484 MucB/RseB, C-terminal domain superfamily MADE_1012535 eaf5bcbbedfa9bcd64e686b2f59d37b9 368 PIRSF PIRSF005427 59 368 3.0E-78 T 13-10-2018 IPR005588 MucB/RseB MADE_1012535 eaf5bcbbedfa9bcd64e686b2f59d37b9 368 Gene3D G3DSA:2.50.20.10 74 259 2.1E-49 T 13-10-2018 MADE_1012535 eaf5bcbbedfa9bcd64e686b2f59d37b9 368 Pfam PF03888 MucB/RseB N-terminal domain 75 257 4.4E-52 T 13-10-2018 IPR033434 MucB/RseB, N-terminal MADE_1003535 92d6c02f6b3f0a80dd43f33a146802b0 284 Gene3D G3DSA:1.10.287.70 122 233 3.9E-32 T 13-10-2018 MADE_1003535 92d6c02f6b3f0a80dd43f33a146802b0 284 SUPERFAMILY SSF81324 17 232 2.2E-30 T 13-10-2018 MADE_1003535 92d6c02f6b3f0a80dd43f33a146802b0 284 Gene3D G3DSA:1.20.120.350 7 121 3.9E-25 T 13-10-2018 IPR027359 Voltage-dependent channel domain superfamily MADE_1003535 92d6c02f6b3f0a80dd43f33a146802b0 284 Pfam PF00520 Ion transport protein 16 234 2.1E-40 T 13-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 MADE_1007505 b99e08c10220ccacfc0ad9b798df2b0f 343 SUPERFAMILY SSF51126 8 317 2.19E-31 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor MADE_1007505 b99e08c10220ccacfc0ad9b798df2b0f 343 SMART SM00710 182 211 560.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1007505 b99e08c10220ccacfc0ad9b798df2b0f 343 SMART SM00710 241 269 260.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1007505 b99e08c10220ccacfc0ad9b798df2b0f 343 SMART SM00710 213 234 59.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1007505 b99e08c10220ccacfc0ad9b798df2b0f 343 SMART SM00710 152 181 1300.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1007505 b99e08c10220ccacfc0ad9b798df2b0f 343 Gene3D G3DSA:2.160.20.10 21 338 5.2E-22 T 13-10-2018 IPR012334 Pectin lyase fold MADE_000001022010 0846eb16156e22ccbf722c148bd6099a 455 Pfam PF07044 Protein of unknown function (DUF1329) 85 450 1.9E-158 T 13-10-2018 IPR010752 Protein of unknown function DUF1329 MADE_000001021245 52df498fbb76f830b30d64c7ded844fc 378 Pfam PF01734 Patatin-like phospholipase 24 204 2.6E-13 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MADE_000001021245 52df498fbb76f830b30d64c7ded844fc 378 Gene3D G3DSA:3.40.1090.10 96 263 9.2E-7 T 13-10-2018 MADE_000001021245 52df498fbb76f830b30d64c7ded844fc 378 Gene3D G3DSA:3.40.1090.10 6 93 2.3E-11 T 13-10-2018 MADE_000001021245 52df498fbb76f830b30d64c7ded844fc 378 SUPERFAMILY SSF52151 20 233 1.07E-34 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MADE_1005345 7a822ae1542e57a1fdda369531be3941 287 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 243 269 - T 13-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 MADE_1005345 7a822ae1542e57a1fdda369531be3941 287 Pfam PF01148 Cytidylyltransferase family 3 282 9.2E-60 T 13-10-2018 MADE_1013885 8e79cb990523a86b9f71fb08073becce 906 Pfam PF13692 Glycosyl transferases group 1 725 860 1.4E-22 T 13-10-2018 MADE_1013885 8e79cb990523a86b9f71fb08073becce 906 SUPERFAMILY SSF53756 538 895 8.16E-20 T 13-10-2018 MADE_1013885 8e79cb990523a86b9f71fb08073becce 906 Pfam PF00535 Glycosyl transferase family 2 272 376 7.6E-19 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1013885 8e79cb990523a86b9f71fb08073becce 906 Gene3D G3DSA:3.40.50.2000 713 881 4.0E-15 T 13-10-2018 MADE_1013885 8e79cb990523a86b9f71fb08073becce 906 SUPERFAMILY SSF53448 262 513 5.16E-47 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013885 8e79cb990523a86b9f71fb08073becce 906 Gene3D G3DSA:3.90.550.10 255 492 1.9E-48 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_000001021695 ba62e33ea6e1aa491b119a0920b97b16 208 Gene3D G3DSA:1.10.3890.10 4 208 8.4E-76 T 13-10-2018 IPR035932 HflD-like superfamily MADE_000001021695 ba62e33ea6e1aa491b119a0920b97b16 208 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 30 196 3.0E-46 T 13-10-2018 MADE_000001021695 ba62e33ea6e1aa491b119a0920b97b16 208 SUPERFAMILY SSF101322 6 205 1.83E-72 T 13-10-2018 IPR035932 HflD-like superfamily MADE_000001021695 ba62e33ea6e1aa491b119a0920b97b16 208 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 205 34.597 T 13-10-2018 IPR007451 High frequency lysogenization protein HflD MADE_000001021695 ba62e33ea6e1aa491b119a0920b97b16 208 Pfam PF04356 Protein of unknown function (DUF489) 8 197 2.1E-76 T 13-10-2018 IPR007451 High frequency lysogenization protein HflD MADE_1020235 9b12950aa9c40a41f3f794e1979b9438 286 Pfam PF11219 Protein of unknown function (DUF3014) 122 277 1.4E-53 T 13-10-2018 IPR021382 Protein of unknown function DUF3014 MADE_1008440 c78bbeb57833b34fb79c0f5757e331a2 535 Gene3D G3DSA:3.90.226.10 1 271 9.4E-95 T 13-10-2018 MADE_1008440 c78bbeb57833b34fb79c0f5757e331a2 535 Pfam PF01039 Carboxyl transferase domain 48 526 5.6E-152 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 MADE_1008440 c78bbeb57833b34fb79c0f5757e331a2 535 SUPERFAMILY SSF52096 237 517 1.33E-89 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1008440 c78bbeb57833b34fb79c0f5757e331a2 535 Gene3D G3DSA:3.90.226.10 274 535 1.1E-104 T 13-10-2018 MADE_1008440 c78bbeb57833b34fb79c0f5757e331a2 535 SUPERFAMILY SSF52096 20 272 4.43E-69 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1008865 5db132c19b4419b92ccdd1b5bb287b72 130 Pfam PF12514 Protein of unknown function (DUF3718) 32 100 7.6E-21 T 13-10-2018 IPR022193 Protein of unknown function DUF3718 MADE_1015515 962d017c39cbd58c8ee1d6b4a1657559 248 SUPERFAMILY SSF52218 20 234 2.16E-61 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1015515 962d017c39cbd58c8ee1d6b4a1657559 248 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 25 234 4.5E-117 T 13-10-2018 IPR014063 Arsenate resistance ArsH MADE_1015515 962d017c39cbd58c8ee1d6b4a1657559 248 Gene3D G3DSA:3.40.50.360 17 248 3.3E-75 T 13-10-2018 IPR029039 Flavoprotein-like superfamily MADE_1015515 962d017c39cbd58c8ee1d6b4a1657559 248 Pfam PF03358 NADPH-dependent FMN reductase 42 185 2.4E-28 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 MADE_1019170 7edc2ec2a7598b6a5d6b3dbfcf79a089 187 Pfam PF00571 CBS domain 43 84 5.1E-5 T 13-10-2018 IPR000644 CBS domain MADE_1019170 7edc2ec2a7598b6a5d6b3dbfcf79a089 187 Pfam PF00571 CBS domain 124 166 2.0E-6 T 13-10-2018 IPR000644 CBS domain MADE_1019170 7edc2ec2a7598b6a5d6b3dbfcf79a089 187 SMART SM00116 41 89 1.0 T 13-10-2018 IPR000644 CBS domain MADE_1019170 7edc2ec2a7598b6a5d6b3dbfcf79a089 187 SMART SM00116 120 167 0.97 T 13-10-2018 IPR000644 CBS domain MADE_1019170 7edc2ec2a7598b6a5d6b3dbfcf79a089 187 SUPERFAMILY SSF54631 42 166 1.03E-16 T 13-10-2018 MADE_1019170 7edc2ec2a7598b6a5d6b3dbfcf79a089 187 Gene3D G3DSA:3.10.580.10 20 173 9.8E-19 T 13-10-2018 MADE_1008390 a0348a42915788d5d9045d8f9f91aba3 440 SUPERFAMILY SSF103473 10 426 1.23E-67 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1008390 a0348a42915788d5d9045d8f9f91aba3 440 Gene3D G3DSA:1.20.1250.20 15 214 3.1E-42 T 13-10-2018 MADE_1008390 a0348a42915788d5d9045d8f9f91aba3 440 Pfam PF07690 Major Facilitator Superfamily 29 379 2.3E-42 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1008390 a0348a42915788d5d9045d8f9f91aba3 440 Gene3D G3DSA:1.20.1250.20 221 429 3.7E-19 T 13-10-2018 MADE_1015395 2c519f31da6d60139052ce3b4473112a 144 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 138 2.3E-57 T 13-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 MADE_1015395 2c519f31da6d60139052ce3b4473112a 144 SUPERFAMILY SSF82784 11 141 1.44E-35 T 13-10-2018 IPR036102 OsmC/Ohr superfamily MADE_1015395 2c519f31da6d60139052ce3b4473112a 144 Pfam PF02566 OsmC-like protein 42 139 4.7E-21 T 13-10-2018 IPR003718 OsmC/Ohr family MADE_1015395 2c519f31da6d60139052ce3b4473112a 144 Gene3D G3DSA:3.30.300.20 2 142 1.9E-41 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta MADE_1008250 674ff9c339ab6c44f3c36bfa9608b6e8 62 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 25 60 3.5E-12 T 13-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 MADE_1008250 674ff9c339ab6c44f3c36bfa9608b6e8 62 SUPERFAMILY SSF46589 19 60 5.75E-10 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 MADE_1015530 d7a042c6c2dfa2df2aafe324e8df8b81 577 PIRSF PIRSF000719 7 577 1.0E-201 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MADE_1015530 d7a042c6c2dfa2df2aafe324e8df8b81 577 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 16 573 0.0 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MADE_1015530 d7a042c6c2dfa2df2aafe324e8df8b81 577 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 8 574 40.073 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MADE_1015530 d7a042c6c2dfa2df2aafe324e8df8b81 577 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 16 570 3.0E-223 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 MADE_1001240 3c31bcc2ca4ce6859080e785317da74d 418 SMART SM00028 262 295 65.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1001240 3c31bcc2ca4ce6859080e785317da74d 418 SMART SM00028 228 261 31.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1001240 3c31bcc2ca4ce6859080e785317da74d 418 SMART SM00028 367 400 63.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1001240 3c31bcc2ca4ce6859080e785317da74d 418 SMART SM00028 333 366 81.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1001240 3c31bcc2ca4ce6859080e785317da74d 418 SUPERFAMILY SSF48452 229 396 5.88E-18 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1001240 3c31bcc2ca4ce6859080e785317da74d 418 Pfam PF14559 Tetratricopeptide repeat 242 305 4.2E-7 T 13-10-2018 MADE_1001240 3c31bcc2ca4ce6859080e785317da74d 418 Gene3D G3DSA:1.25.40.10 204 417 3.3E-21 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1013430 9e958f904dc09452d3f6dfbde39d131b 225 Pfam PF01794 Ferric reductase like transmembrane component 54 167 4.1E-16 T 13-10-2018 IPR013130 Ferric reductase transmembrane component-like domain MADE_1013430 9e958f904dc09452d3f6dfbde39d131b 225 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 14 207 19.185 T 13-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 MADE_1006565 535624b9a60362e0548004ae8257422d 856 Pfam PF00593 TonB dependent receptor 387 849 8.0E-36 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1006565 535624b9a60362e0548004ae8257422d 856 Gene3D G3DSA:2.40.170.20 385 835 8.7E-52 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1006565 535624b9a60362e0548004ae8257422d 856 Gene3D G3DSA:2.170.130.10 40 185 4.4E-31 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1006565 535624b9a60362e0548004ae8257422d 856 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 181 1.4E-20 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1006565 535624b9a60362e0548004ae8257422d 856 SUPERFAMILY SSF56935 43 848 1.05E-101 T 13-10-2018 MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 Gene3D G3DSA:2.60.40.1250 45 179 1.4E-42 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 ProSitePatterns PS00194 Thioredoxin family active site. 519 537 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 Gene3D G3DSA:3.40.30.10 486 612 1.8E-29 T 13-10-2018 MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 SUPERFAMILY SSF74863 50 163 5.36E-39 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 Pfam PF13899 Thioredoxin-like 503 584 2.8E-11 T 13-10-2018 MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 SUPERFAMILY SSF52833 492 609 2.62E-22 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 15 611 34.531 T 13-10-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 Pfam PF11412 Disulphide bond corrector protein DsbC 52 160 5.3E-31 T 13-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain MADE_1019645 77d3c09cb68c5a85b56df18531e82d3c 626 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 215 414 3.4E-18 T 13-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 Gene3D G3DSA:3.40.1160.10 9 287 4.3E-88 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 Pfam PF00696 Amino acid kinase family 25 237 2.0E-30 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 SUPERFAMILY SSF53633 5 288 2.49E-66 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 SUPERFAMILY SSF55729 291 412 4.22E-19 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 Pfam PF00583 Acetyltransferase (GNAT) family 319 396 8.6E-8 T 13-10-2018 IPR000182 GNAT domain MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 9 434 1.1E-173 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 436 198.589 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 PIRSF PIRSF000423 1 436 4.7E-179 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 MADE_1002640 ef8e80b5fc1987c47c5240e0ec012d24 436 Gene3D G3DSA:3.40.630.30 288 436 2.0E-36 T 13-10-2018 MADE_1007540 cc2f9a3e8d39127ada423f104298accf 292 Pfam PF00535 Glycosyl transferase family 2 10 167 1.2E-23 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1007540 cc2f9a3e8d39127ada423f104298accf 292 SUPERFAMILY SSF53448 6 260 8.16E-41 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1007540 cc2f9a3e8d39127ada423f104298accf 292 Gene3D G3DSA:3.90.550.10 1 247 9.5E-43 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019110 5fe570d6064469757ee3f194f8e8d2da 135 Gene3D G3DSA:3.10.450.50 2 135 1.3E-22 T 13-10-2018 MADE_1019110 5fe570d6064469757ee3f194f8e8d2da 135 SUPERFAMILY SSF54427 4 131 8.58E-17 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1019110 5fe570d6064469757ee3f194f8e8d2da 135 Pfam PF14534 Domain of unknown function (DUF4440) 5 120 3.2E-8 T 13-10-2018 IPR027843 Domain of unknown function DUF4440 MADE_000001022395 85d8aeabd4661e015d917e0eea2130dc 180 Gene3D G3DSA:2.60.120.10 26 150 7.5E-9 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_000001022395 85d8aeabd4661e015d917e0eea2130dc 180 TIGRFAM TIGR04366 cupin_WbuC: cupin fold metalloprotein, WbuC family 23 154 2.1E-50 T 13-10-2018 IPR027565 Cupin fold metalloprotein, WbuC family MADE_000001022395 85d8aeabd4661e015d917e0eea2130dc 180 SUPERFAMILY SSF51182 46 154 1.48E-17 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_000001022395 85d8aeabd4661e015d917e0eea2130dc 180 Pfam PF09313 Domain of unknown function (DUF1971) 63 130 1.3E-5 T 13-10-2018 IPR015392 Domain of unknown function DUF1971 MADE_1010795 6daab57650b453743900b4fbd76afba3 365 SUPERFAMILY SSF51395 2 352 5.92E-97 T 13-10-2018 MADE_1010795 6daab57650b453743900b4fbd76afba3 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 352 4.5E-69 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MADE_1010795 6daab57650b453743900b4fbd76afba3 365 Gene3D G3DSA:3.20.20.70 4 361 1.1E-104 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1000720 64eaa1008d31876e3e6c4638825a4e7f 642 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 143 596 99.747 T 13-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MADE_1000720 64eaa1008d31876e3e6c4638825a4e7f 642 Gene3D G3DSA:3.20.20.540 216 527 2.0E-154 T 13-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MADE_1000720 64eaa1008d31876e3e6c4638825a4e7f 642 Pfam PF01964 Radical SAM ThiC family 144 592 1.4E-200 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MADE_1000720 64eaa1008d31876e3e6c4638825a4e7f 642 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 143 595 3.1E-220 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MADE_1000720 64eaa1008d31876e3e6c4638825a4e7f 642 Pfam PF13667 ThiC-associated domain 23 103 4.3E-30 T 13-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 6.8E-41 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 SUPERFAMILY SSF52490 14 205 1.44E-69 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 342 37.635 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 Gene3D G3DSA:3.30.1330.20 221 327 5.9E-33 T 13-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 SMART SM00865 207 325 2.0E-53 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 PRINTS PR00423 Cell division protein FtsZ signature 212 233 2.7E-52 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 PRINTS PR00423 Cell division protein FtsZ signature 189 211 2.7E-52 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 PRINTS PR00423 Cell division protein FtsZ signature 126 147 2.7E-52 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 PRINTS PR00423 Cell division protein FtsZ signature 98 118 2.7E-52 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 328 5.5E-134 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 Pfam PF12327 FtsZ family, C-terminal domain 222 316 4.7E-35 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 Gene3D G3DSA:3.40.50.1440 4 220 7.0E-80 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 SUPERFAMILY SSF55307 204 320 1.47E-40 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MADE_1015125 8b827d27cb843e9eccea62d2bd7e7c0c 388 SMART SM00864 13 205 6.2E-113 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1002375 7bbd259152f3d35afb0233d0cde271a6 217 Pfam PF02834 LigT like Phosphoesterase 63 110 3.3E-7 T 13-10-2018 IPR014051 Phosphoesterase, HXTX MADE_1002375 7bbd259152f3d35afb0233d0cde271a6 217 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 200 19.625 T 13-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 MADE_1002375 7bbd259152f3d35afb0233d0cde271a6 217 SUPERFAMILY SSF55144 61 200 5.41E-32 T 13-10-2018 IPR009097 Cyclic phosphodiesterase MADE_1002375 7bbd259152f3d35afb0233d0cde271a6 217 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 63 200 2.2E-29 T 13-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 MADE_1002375 7bbd259152f3d35afb0233d0cde271a6 217 Gene3D G3DSA:3.90.1140.10 46 201 2.4E-33 T 13-10-2018 MADE_1014465 f8d86600793c3b17c333e783b3861697 435 Pfam PF00557 Metallopeptidase family M24 199 404 3.8E-46 T 13-10-2018 IPR000994 Peptidase M24 MADE_1014465 f8d86600793c3b17c333e783b3861697 435 Gene3D G3DSA:3.90.230.10 190 420 5.6E-62 T 13-10-2018 MADE_1014465 f8d86600793c3b17c333e783b3861697 435 Pfam PF01321 Creatinase/Prolidase N-terminal domain 57 190 3.1E-19 T 13-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 MADE_1014465 f8d86600793c3b17c333e783b3861697 435 SUPERFAMILY SSF53092 38 189 1.53E-26 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MADE_1014465 f8d86600793c3b17c333e783b3861697 435 Gene3D G3DSA:3.40.350.10 28 189 5.1E-44 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal MADE_1014465 f8d86600793c3b17c333e783b3861697 435 SUPERFAMILY SSF55920 190 417 7.98E-58 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like MADE_1013055 016f08d2ac748816819b422bc704625c 531 SUPERFAMILY SSF51621 11 513 2.15E-125 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MADE_1013055 016f08d2ac748816819b422bc704625c 531 Gene3D G3DSA:3.20.20.60 414 530 3.2E-20 T 13-10-2018 MADE_1013055 016f08d2ac748816819b422bc704625c 531 Pfam PF00463 Isocitrate lyase family 316 390 2.3E-10 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MADE_1013055 016f08d2ac748816819b422bc704625c 531 Pfam PF00463 Isocitrate lyase family 97 268 1.7E-20 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MADE_1013055 016f08d2ac748816819b422bc704625c 531 Pfam PF00463 Isocitrate lyase family 432 529 1.6E-11 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MADE_1013055 016f08d2ac748816819b422bc704625c 531 PIRSF PIRSF001362 415 530 9.4E-7 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MADE_1013055 016f08d2ac748816819b422bc704625c 531 PIRSF PIRSF001362 1 276 1.6E-29 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MADE_1013055 016f08d2ac748816819b422bc704625c 531 PIRSF PIRSF001362 278 410 1.7E-13 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 MADE_1016750 ea7e7a8e327caf48f94e755a558f5ad0 330 PIRSF PIRSF029693 2 330 1.3E-145 T 13-10-2018 IPR016936 Uncharacterised conserved protein UCP029693 MADE_1016750 ea7e7a8e327caf48f94e755a558f5ad0 330 Pfam PF10095 Uncharacterized protein conserved in bacteria (DUF2333) 10 330 1.6E-148 T 13-10-2018 IPR016936 Uncharacterised conserved protein UCP029693 MADE_1019885 1751fda3ccd3124a9a7c964bc07247e7 462 Pfam PF00171 Aldehyde dehydrogenase family 3 454 2.0E-141 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_1019885 1751fda3ccd3124a9a7c964bc07247e7 462 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 257 268 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MADE_1019885 1751fda3ccd3124a9a7c964bc07247e7 462 Gene3D G3DSA:3.40.309.10 236 426 1.3E-149 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_1019885 1751fda3ccd3124a9a7c964bc07247e7 462 SUPERFAMILY SSF53720 3 456 1.83E-143 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1019885 1751fda3ccd3124a9a7c964bc07247e7 462 Gene3D G3DSA:3.40.605.10 3 454 1.3E-149 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_000001023610 6877a95c4eee84a79b19fa741c908f9a 154 SUPERFAMILY SSF103039 1 152 1.57E-34 T 13-10-2018 IPR028976 CheC-like superfamily MADE_000001023610 6877a95c4eee84a79b19fa741c908f9a 154 Pfam PF13690 Chemotaxis phosphatase CheX 42 139 2.5E-24 T 13-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain MADE_000001023610 6877a95c4eee84a79b19fa741c908f9a 154 Gene3D G3DSA:3.40.1550.10 1 154 9.8E-45 T 13-10-2018 IPR028976 CheC-like superfamily MADE_1005210 17d58fc83a40c731ba60d786eb7bd62b 350 Pfam PF13413 Helix-turn-helix domain 25 86 4.4E-13 T 13-10-2018 MADE_1005210 17d58fc83a40c731ba60d786eb7bd62b 350 SUPERFAMILY SSF47413 22 88 4.29E-5 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1005210 17d58fc83a40c731ba60d786eb7bd62b 350 Pfam PF13464 Domain of unknown function (DUF4115) 276 348 9.0E-22 T 13-10-2018 IPR025194 Domain of unknown function DUF4115 MADE_1005210 17d58fc83a40c731ba60d786eb7bd62b 350 Gene3D G3DSA:1.10.260.40 10 120 8.6E-22 T 13-10-2018 MADE_1008210 899a89db3912988cac2aababc627fab8 823 SUPERFAMILY SSF51126 283 598 4.53E-18 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor MADE_1008210 899a89db3912988cac2aababc627fab8 823 SMART SM00710 339 361 480.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1008210 899a89db3912988cac2aababc627fab8 823 SMART SM00710 487 508 1600.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1008210 899a89db3912988cac2aababc627fab8 823 SMART SM00710 316 338 550.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1008210 899a89db3912988cac2aababc627fab8 823 SMART SM00710 578 599 6800.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat MADE_1008210 899a89db3912988cac2aababc627fab8 823 Gene3D G3DSA:2.160.20.10 216 619 2.6E-8 T 13-10-2018 IPR012334 Pectin lyase fold MADE_1012675 326b242969d0a8e2c456a89077273013 519 Pfam PF03023 MviN-like protein 30 470 4.7E-146 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 4 509 1.9E-139 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PRINTS PR01806 Virulence factor MviN signature 418 435 1.7E-78 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PRINTS PR01806 Virulence factor MviN signature 54 70 1.7E-78 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PRINTS PR01806 Virulence factor MviN signature 268 294 1.7E-78 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PRINTS PR01806 Virulence factor MviN signature 366 385 1.7E-78 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PRINTS PR01806 Virulence factor MviN signature 35 54 1.7E-78 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PRINTS PR01806 Virulence factor MviN signature 142 166 1.7E-78 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PRINTS PR01806 Virulence factor MviN signature 166 187 1.7E-78 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 5 476 20.127 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1012675 326b242969d0a8e2c456a89077273013 519 PIRSF PIRSF002869 2 517 3.0E-156 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ MADE_1006905 4726898d2e0fe4fa3f6154135bd5a1e2 270 SUPERFAMILY SSF89550 3 249 6.28E-34 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 MADE_1006905 4726898d2e0fe4fa3f6154135bd5a1e2 270 Gene3D G3DSA:1.10.150.650 71 142 9.0E-65 T 13-10-2018 MADE_1006905 4726898d2e0fe4fa3f6154135bd5a1e2 270 Gene3D G3DSA:3.20.20.140 2 223 9.0E-65 T 13-10-2018 MADE_1014090 a9fd566d2484ea2ba2c77f9a085a026f 1156 Pfam PF05359 Domain of Unknown Function (DUF748) 469 626 5.1E-18 T 13-10-2018 IPR008023 Protein of unknown function DUF748 MADE_1014090 a9fd566d2484ea2ba2c77f9a085a026f 1156 Pfam PF05359 Domain of Unknown Function (DUF748) 718 862 1.9E-34 T 13-10-2018 IPR008023 Protein of unknown function DUF748 MADE_1014090 a9fd566d2484ea2ba2c77f9a085a026f 1156 Pfam PF05359 Domain of Unknown Function (DUF748) 182 339 4.4E-9 T 13-10-2018 IPR008023 Protein of unknown function DUF748 MADE_1013525 9725e3f62b74dc94ff02dc800f6229c5 82 Gene3D G3DSA:3.10.20.30 2 82 9.6E-22 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1013525 9725e3f62b74dc94ff02dc800f6229c5 82 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 82 3.7E-14 T 13-10-2018 IPR010038 MoaD, archaeal-type MADE_1013525 9725e3f62b74dc94ff02dc800f6229c5 82 Pfam PF02597 ThiS family 5 82 7.8E-19 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 MADE_1013525 9725e3f62b74dc94ff02dc800f6229c5 82 SUPERFAMILY SSF54285 1 80 2.43E-19 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MADE_000001022070 50fab39d51a3ae4b9a8aaaa79c7a2977 190 Gene3D G3DSA:1.20.120.1760 2 182 8.3E-18 T 13-10-2018 MADE_000001022070 50fab39d51a3ae4b9a8aaaa79c7a2977 190 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MADE_000001022070 50fab39d51a3ae4b9a8aaaa79c7a2977 190 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 70 1.9E-16 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MADE_000001022070 50fab39d51a3ae4b9a8aaaa79c7a2977 190 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 183 1.6E-49 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MADE_000001022070 50fab39d51a3ae4b9a8aaaa79c7a2977 190 PIRSF PIRSF000847 1 190 2.1E-43 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 MADE_1009685 131ff420d6d141a225ff1fdba042a808 291 Gene3D G3DSA:3.30.479.10 13 151 2.3E-21 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 MADE_1009685 131ff420d6d141a225ff1fdba042a808 291 SUPERFAMILY SSF55620 155 289 2.72E-24 T 13-10-2018 MADE_1009685 131ff420d6d141a225ff1fdba042a808 291 SUPERFAMILY SSF55620 1 156 5.06E-29 T 13-10-2018 MADE_1009685 131ff420d6d141a225ff1fdba042a808 291 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 24 71 2.0E-7 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MADE_1009685 131ff420d6d141a225ff1fdba042a808 291 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 152 290 1.4E-7 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 MADE_1009685 131ff420d6d141a225ff1fdba042a808 291 Gene3D G3DSA:3.30.479.10 152 290 3.0E-8 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 MADE_1018990 32f70afd747a5b8857f9ad2a5c5d9a65 250 Pfam PF01925 Sulfite exporter TauE/SafE 11 242 4.3E-21 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MADE_1006680 4443b7b3abbd9c93f0cd197737869833 218 Gene3D G3DSA:3.40.50.620 2 213 7.2E-72 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1006680 4443b7b3abbd9c93f0cd197737869833 218 SUPERFAMILY SSF52402 3 217 1.41E-63 T 13-10-2018 MADE_1006680 4443b7b3abbd9c93f0cd197737869833 218 PIRSF PIRSF006293 1 218 3.3E-77 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MADE_1006680 4443b7b3abbd9c93f0cd197737869833 218 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 202 2.8E-64 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MADE_1006680 4443b7b3abbd9c93f0cd197737869833 218 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 3 215 50.254 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MADE_1006680 4443b7b3abbd9c93f0cd197737869833 218 Pfam PF06508 Queuosine biosynthesis protein QueC 5 209 3.1E-67 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 MADE_000001022250 1b85c87d10d27f28fd70f6d2eb225a5d 265 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 53 75 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MADE_000001022250 1b85c87d10d27f28fd70f6d2eb225a5d 265 Gene3D G3DSA:1.20.120.1760 7 140 1.7E-16 T 13-10-2018 MADE_000001022250 1b85c87d10d27f28fd70f6d2eb225a5d 265 Pfam PF01066 CDP-alcohol phosphatidyltransferase 12 75 1.3E-15 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 MADE_000001022250 1b85c87d10d27f28fd70f6d2eb225a5d 265 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 19 179 3.2E-36 T 13-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 MADE_1000535 8f3f604be1f73ec495966459b336019c 328 Gene3D G3DSA:3.30.460.10 7 159 4.0E-18 T 13-10-2018 MADE_1000535 8f3f604be1f73ec495966459b336019c 328 Pfam PF04607 Region found in RelA / SpoT proteins 50 176 3.1E-17 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 MADE_1000535 8f3f604be1f73ec495966459b336019c 328 SMART SM00954 49 179 3.7E-16 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 MADE_1000535 8f3f604be1f73ec495966459b336019c 328 SUPERFAMILY SSF81301 27 211 3.6E-30 T 13-10-2018 MADE_1013955 2c3a0a36079b61d18da71be49df351f4 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 3.0E-9 T 13-10-2018 MADE_1013955 2c3a0a36079b61d18da71be49df351f4 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013955 2c3a0a36079b61d18da71be49df351f4 38 SUPERFAMILY SSF57840 1 38 3.4E-17 T 13-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013955 2c3a0a36079b61d18da71be49df351f4 38 Pfam PF00444 Ribosomal protein L36 1 38 2.5E-20 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013955 2c3a0a36079b61d18da71be49df351f4 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.304 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013955 2c3a0a36079b61d18da71be49df351f4 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 2.3E-22 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1015665 f36a61a11cf4524fc22824840c8cece9 412 Gene3D G3DSA:3.30.565.10 279 401 1.0E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015665 f36a61a11cf4524fc22824840c8cece9 412 SUPERFAMILY SSF55874 291 377 9.85E-5 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1015665 f36a61a11cf4524fc22824840c8cece9 412 Pfam PF07730 Histidine kinase 213 278 1.6E-13 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 MADE_000001021865 d2aac126d4084c514332470980b03b71 304 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 131 293 5.0E-37 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021865 d2aac126d4084c514332470980b03b71 304 Gene3D G3DSA:3.30.70.270 118 298 6.1E-44 T 13-10-2018 MADE_000001021865 d2aac126d4084c514332470980b03b71 304 SMART SM00267 122 295 2.0E-42 T 13-10-2018 IPR000160 GGDEF domain MADE_000001021865 d2aac126d4084c514332470980b03b71 304 SUPERFAMILY SSF55073 138 296 2.04E-35 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_000001021865 d2aac126d4084c514332470980b03b71 304 Pfam PF00990 Diguanylate cyclase, GGDEF domain 135 289 2.5E-34 T 13-10-2018 IPR000160 GGDEF domain MADE_1019975 62b90a6c413022542bb9b42096fa20b5 261 Gene3D G3DSA:1.10.287.460 29 143 1.0E-26 T 13-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 MADE_1019975 62b90a6c413022542bb9b42096fa20b5 261 SUPERFAMILY SSF54534 45 251 8.75E-59 T 13-10-2018 MADE_1019975 62b90a6c413022542bb9b42096fa20b5 261 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 164 249 1.4E-26 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain MADE_1019975 62b90a6c413022542bb9b42096fa20b5 261 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 37 155 1.6E-29 T 13-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 MADE_1019975 62b90a6c413022542bb9b42096fa20b5 261 Gene3D G3DSA:3.10.50.40 144 250 9.0E-43 T 13-10-2018 MADE_1006685 21eb4fc8d1c672969368bce409b91a13 224 Gene3D G3DSA:3.20.20.70 3 224 6.8E-53 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1006685 21eb4fc8d1c672969368bce409b91a13 224 Pfam PF04055 Radical SAM superfamily 27 129 4.0E-8 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1006685 21eb4fc8d1c672969368bce409b91a13 224 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 224 35.588 T 13-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MADE_1006685 21eb4fc8d1c672969368bce409b91a13 224 Pfam PF13394 4Fe-4S single cluster domain 25 130 1.3E-13 T 13-10-2018 MADE_1006685 21eb4fc8d1c672969368bce409b91a13 224 PIRSF PIRSF000370 2 224 2.5E-64 T 13-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MADE_1006685 21eb4fc8d1c672969368bce409b91a13 224 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 10 224 7.0E-112 T 13-10-2018 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 MADE_1006685 21eb4fc8d1c672969368bce409b91a13 224 SUPERFAMILY SSF102114 27 200 1.05E-7 T 13-10-2018 MADE_000001023600 2548febecdffcc04f42d86ce2b87f8a9 154 PIRSF PIRSF016548 1 153 8.0E-47 T 13-10-2018 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 MADE_000001023600 2548febecdffcc04f42d86ce2b87f8a9 154 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 1 144 6.9E-49 T 13-10-2018 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 MADE_000001023600 2548febecdffcc04f42d86ce2b87f8a9 154 Gene3D G3DSA:1.20.120.1370 1 151 1.1E-46 T 13-10-2018 IPR038309 Rsd/AlgQ superfamily MADE_000001023430 44a7a641f447421e9d0bb279fbfe0a67 354 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 7 332 2.5E-91 T 13-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 MADE_000001023430 44a7a641f447421e9d0bb279fbfe0a67 354 SUPERFAMILY SSF55909 2 332 2.14E-96 T 13-10-2018 MADE_000001023430 44a7a641f447421e9d0bb279fbfe0a67 354 Gene3D G3DSA:3.75.10.10 2 341 1.3E-96 T 13-10-2018 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 Gene3D G3DSA:1.10.1020.10 59 158 1.3E-85 T 13-10-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 Gene3D G3DSA:3.40.50.150 9 241 1.3E-85 T 13-10-2018 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 TIGRFAM TIGR00571 dam: DNA adenine methylase 7 269 1.7E-91 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 PIRSF PIRSF000398 3 276 1.1E-66 T 13-10-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 SUPERFAMILY SSF53335 7 270 6.55E-74 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 33 47 4.9E-19 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 52 65 4.9E-19 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 12 28 4.9E-19 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 177 189 4.9E-19 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MADE_1002550 7000e407d19333e2d239d6ebfc727e35 293 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 12 252 9.7E-68 T 13-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 MADE_1020060 957dd892954cf4513343f7829f58a3fa 214 Gene3D G3DSA:3.40.30.10 33 207 3.0E-44 T 13-10-2018 MADE_1020060 957dd892954cf4513343f7829f58a3fa 214 Pfam PF02630 SCO1/SenC 42 186 2.3E-34 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020060 957dd892954cf4513343f7829f58a3fa 214 SUPERFAMILY SSF52833 43 195 4.57E-45 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 SUPERFAMILY SSF51735 9 252 4.32E-84 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 9.8E-66 T 13-10-2018 MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.4E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.4E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.4E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.4E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.4E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.4E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 Gene3D G3DSA:3.40.50.720 1 252 1.7E-80 T 13-10-2018 MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.2E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.2E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1013720 f52e9085277f3cd6c1590c580d8c0dfe 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.2E-11 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1006540 6689018df41cf5ed52d1d03e3f4fb761 515 Pfam PF04293 SpoVR like protein 26 456 2.3E-174 T 13-10-2018 IPR007390 Sporulation stage V, protein R MADE_1011040 8a897e45ab424ce0152656b69ee5f298 96 Gene3D G3DSA:3.30.2310.20 6 96 7.5E-7 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1011040 8a897e45ab424ce0152656b69ee5f298 96 SUPERFAMILY SSF143011 8 89 3.34E-6 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1011040 8a897e45ab424ce0152656b69ee5f298 96 Pfam PF15781 ParE-like toxin of type II bacterial toxin-antitoxin system 7 93 2.2E-37 T 13-10-2018 IPR031552 Type II bacterial toxin-antitoxin system, ParE-like toxin MADE_1002735 0390d022715866286c50984fb2d05e82 142 Pfam PF03203 MerC mercury resistance protein 12 120 2.7E-26 T 13-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 MADE_1000730 3466a75c26e2c71a38a8d529433b6acc 390 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 52 381 2.6E-74 T 13-10-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX MADE_000001021820 1077d4e49c10aab5125398b04621ecc4 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 156 5.4E-74 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MADE_000001021820 1077d4e49c10aab5125398b04621ecc4 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 26.267 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MADE_000001021820 1077d4e49c10aab5125398b04621ecc4 156 PIRSF PIRSF004505 1 155 2.2E-39 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MADE_000001021820 1077d4e49c10aab5125398b04621ecc4 156 Pfam PF02590 Predicted SPOUT methyltransferase 2 154 1.5E-45 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 MADE_000001021820 1077d4e49c10aab5125398b04621ecc4 156 Gene3D G3DSA:3.40.1280.10 1 156 3.2E-49 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_000001021820 1077d4e49c10aab5125398b04621ecc4 156 SUPERFAMILY SSF75217 2 154 8.37E-49 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 SMART SM01008 34 141 1.8E-34 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 Gene3D G3DSA:3.30.365.10 155 410 7.9E-263 T 13-10-2018 MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 166 708 5.2E-188 T 13-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 SUPERFAMILY SSF54665 14 141 2.22E-32 T 13-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 20 779 0.0 T 13-10-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 34 132 6.7E-20 T 13-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 Gene3D G3DSA:3.90.1170.50 21 141 7.9E-263 T 13-10-2018 MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 Gene3D G3DSA:3.30.365.10 142 774 7.9E-263 T 13-10-2018 MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 Gene3D G3DSA:3.30.365.10 191 285 7.9E-263 T 13-10-2018 MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 Gene3D G3DSA:3.30.365.10 462 610 7.9E-263 T 13-10-2018 MADE_1007935 9639d40b51a75de63b6f04e302ac9a6c 788 SUPERFAMILY SSF56003 141 776 3.53E-184 T 13-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 MADE_000001021965 337303e457613ae4dff045e70d4c586b 502 Pfam PF00474 Sodium:solute symporter family 32 435 1.4E-88 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_000001021965 337303e457613ae4dff045e70d4c586b 502 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 496 2.6E-195 T 13-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 MADE_000001021965 337303e457613ae4dff045e70d4c586b 502 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 32 435 4.5E-84 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_000001021965 337303e457613ae4dff045e70d4c586b 502 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 154 179 - T 13-10-2018 IPR018212 Sodium/solute symporter, conserved site MADE_000001021965 337303e457613ae4dff045e70d4c586b 502 Gene3D G3DSA:1.20.1730.10 12 501 4.1E-78 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 PRINTS PR00162 Rieske 2Fe-2S subunit signature 132 143 2.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 PRINTS PR00162 Rieske 2Fe-2S subunit signature 163 175 2.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 PRINTS PR00162 Rieske 2Fe-2S subunit signature 176 188 2.6E-8 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 22 204 1.4E-71 T 13-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 15 53 3.3E-17 T 13-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 Gene3D G3DSA:1.20.5.510 13 53 1.6E-6 T 13-10-2018 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 Pfam PF00355 Rieske [2Fe-2S] domain 124 189 5.1E-10 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 Gene3D G3DSA:2.102.10.10 56 204 7.8E-47 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MADE_000001020805 e6a33f154d201c46e840357e4d45050f 210 SUPERFAMILY SSF50022 43 202 4.16E-40 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MADE_000001020700 8db0bd7a77927e4bdf794421414f7933 281 Gene3D G3DSA:1.20.120.1490 177 278 2.5E-6 T 13-10-2018 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 Pfam PF00175 Oxidoreductase NAD-binding domain 413 518 2.6E-17 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 SUPERFAMILY SSF54292 526 643 7.47E-25 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 Gene3D G3DSA:3.10.20.30 546 644 4.3E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 449 460 2.0E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 412 431 2.0E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 504 512 2.0E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 352 359 2.0E-5 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 Gene3D G3DSA:2.40.30.10 301 402 2.0E-26 T 13-10-2018 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 SUPERFAMILY SSF52343 392 534 2.1E-36 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 SUPERFAMILY SSF63380 303 403 1.7E-25 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 Gene3D G3DSA:3.40.50.80 407 541 1.4E-32 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 Pfam PF00970 Oxidoreductase FAD-binding domain 304 402 7.0E-14 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 594 602 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00406 Cytochrome B5 reductase signature 352 359 4.8E-9 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00406 Cytochrome B5 reductase signature 412 431 4.8E-9 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00406 Cytochrome B5 reductase signature 504 512 4.8E-9 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 PRINTS PR00406 Cytochrome B5 reductase signature 389 403 4.8E-9 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 MADE_1001640 30674c093c4ac78ab82d72fbb62126ac 644 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 568 637 2.6E-14 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 21 155 3.4E-60 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 Pfam PF02556 Preprotein translocase subunit SecB 17 155 2.5E-57 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 Gene3D G3DSA:3.10.420.10 14 165 4.9E-59 T 13-10-2018 IPR035958 SecB-like superfamily MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 109 131 4.6E-38 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 85 105 4.6E-38 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 135 153 4.6E-38 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 25 42 4.6E-38 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 SUPERFAMILY SSF54611 13 152 1.4E-53 T 13-10-2018 IPR035958 SecB-like superfamily MADE_1002710 6266b6d6bc42fdcc844bffac8084879d 169 Hamap MF_00821 Protein-export protein SecB [secB]. 1 157 33.78 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 MADE_1014320 b48b25c8305c9d4ef14d2b1d3174b563 424 Gene3D G3DSA:3.40.50.2300 30 364 6.6E-133 T 13-10-2018 MADE_1014320 b48b25c8305c9d4ef14d2b1d3174b563 424 Pfam PF13433 Periplasmic binding protein domain 28 396 7.6E-174 T 13-10-2018 MADE_1014320 b48b25c8305c9d4ef14d2b1d3174b563 424 Gene3D G3DSA:3.40.50.2300 143 384 6.6E-133 T 13-10-2018 MADE_1014320 b48b25c8305c9d4ef14d2b1d3174b563 424 SUPERFAMILY SSF53822 27 400 8.72E-89 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1014320 b48b25c8305c9d4ef14d2b1d3174b563 424 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 28 393 2.2E-173 T 13-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like MADE_000001021355 cae6cf5f42698ca2884d3553a16a6766 203 Gene3D G3DSA:3.40.50.10610 33 201 3.9E-5 T 13-10-2018 MADE_000001021355 cae6cf5f42698ca2884d3553a16a6766 203 SUPERFAMILY SSF159594 40 201 2.88E-19 T 13-10-2018 MADE_000001021355 cae6cf5f42698ca2884d3553a16a6766 203 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 42 195 9.9E-27 T 13-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component MADE_1007525 bb30e397ca2ab26d7c2f636c63c780e0 403 Pfam PF13579 Glycosyl transferase 4-like domain 22 183 2.4E-11 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1007525 bb30e397ca2ab26d7c2f636c63c780e0 403 Pfam PF00534 Glycosyl transferases group 1 212 371 3.0E-40 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1007525 bb30e397ca2ab26d7c2f636c63c780e0 403 SUPERFAMILY SSF53756 1 400 9.77E-69 T 13-10-2018 MADE_1007525 bb30e397ca2ab26d7c2f636c63c780e0 403 Gene3D G3DSA:3.40.50.2000 1 201 3.1E-24 T 13-10-2018 MADE_1007525 bb30e397ca2ab26d7c2f636c63c780e0 403 Gene3D G3DSA:3.40.50.2000 202 387 2.2E-42 T 13-10-2018 MADE_1011935 e0a418cca9944150e1cc2b4aab2ec19a 98 PIRSF PIRSF029218 1 98 1.9E-31 T 13-10-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 MADE_1011935 e0a418cca9944150e1cc2b4aab2ec19a 98 Gene3D G3DSA:3.30.2310.20 1 97 1.3E-25 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1011935 e0a418cca9944150e1cc2b4aab2ec19a 98 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 92 7.3E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 Pfam PF00403 Heavy-metal-associated domain 25 85 1.1E-13 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 Gene3D G3DSA:3.30.70.100 17 94 5.8E-17 T 13-10-2018 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 PRINTS PR00946 Mercury scavenger protein signature 47 62 8.4E-27 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 PRINTS PR00946 Mercury scavenger protein signature 76 90 8.4E-27 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 PRINTS PR00946 Mercury scavenger protein signature 62 76 8.4E-27 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 PRINTS PR00946 Mercury scavenger protein signature 20 31 8.4E-27 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 PRINTS PR00946 Mercury scavenger protein signature 31 47 8.4E-27 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 PRINTS PR00946 Mercury scavenger protein signature 2 20 8.4E-27 T 13-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 ProSitePatterns PS01047 Heavy-metal-associated domain. 28 57 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 TIGRFAM TIGR02052 MerP: mercuric transport protein periplasmic component 1 90 1.4E-37 T 13-10-2018 IPR011795 Mercuric transport protein periplasmic component GO:0015097|GO:0015694|GO:0042597|GO:0045340|GO:0046689 MADE_1005515 245e415088fa3c62b305a119bb9b0cec 94 SUPERFAMILY SSF55008 19 91 2.62E-18 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MADE_1008570 36966e24e84f746d0a50f9744f3b5624 500 TIGRFAM TIGR03503 TIGR03503: TIGR03503 family protein 63 449 3.8E-129 T 13-10-2018 IPR020010 Conserved hypothetical protein CHP03503 MADE_1016985 62d84722c3d5c888a2fbfeb91c9e9f14 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.9E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1016985 62d84722c3d5c888a2fbfeb91c9e9f14 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.9E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1016985 62d84722c3d5c888a2fbfeb91c9e9f14 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.9E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1016985 62d84722c3d5c888a2fbfeb91c9e9f14 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.9E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1016985 62d84722c3d5c888a2fbfeb91c9e9f14 241 Pfam PF00106 short chain dehydrogenase 4 199 5.3E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1016985 62d84722c3d5c888a2fbfeb91c9e9f14 241 Gene3D G3DSA:3.40.50.720 2 241 5.3E-39 T 13-10-2018 MADE_1016985 62d84722c3d5c888a2fbfeb91c9e9f14 241 SUPERFAMILY SSF51735 4 241 1.7E-41 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 Pfam PF00691 OmpA family 287 382 5.3E-18 T 13-10-2018 IPR006665 OmpA-like domain MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 Gene3D G3DSA:4.10.1080.10 202 281 2.1E-5 T 13-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 PRINTS PR01021 OMPA domain signature 317 332 3.0E-5 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 PRINTS PR01021 OMPA domain signature 332 348 3.0E-5 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 SUPERFAMILY SSF103088 257 388 2.88E-28 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 Gene3D G3DSA:2.40.160.20 28 173 7.6E-7 T 13-10-2018 MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 Gene3D G3DSA:3.30.1330.60 282 394 1.7E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 Pfam PF02412 Thrombospondin type 3 repeat 243 261 0.0042 T 13-10-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 Pfam PF02412 Thrombospondin type 3 repeat 182 200 0.013 T 13-10-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 Pfam PF02412 Thrombospondin type 3 repeat 210 230 4.1E-4 T 13-10-2018 IPR003367 Thrombospondin, type 3-like repeat GO:0005509|GO:0007155 Reactome: R-HSA-186797 MADE_000001023620 4b0be547120b96cec82bb3e6f3695eaa 398 SUPERFAMILY SSF103647 180 263 3.27E-23 T 13-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 MADE_1000020 620fc0ca46c24e2a04e66f6f8d70df32 374 Gene3D G3DSA:3.40.50.300 19 347 2.5E-84 T 13-10-2018 MADE_1000020 620fc0ca46c24e2a04e66f6f8d70df32 374 Gene3D G3DSA:1.20.1050.90 133 312 2.5E-84 T 13-10-2018 MADE_1000020 620fc0ca46c24e2a04e66f6f8d70df32 374 ProSitePatterns PS00618 RecF protein signature 2. 313 331 - T 13-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 MADE_1000020 620fc0ca46c24e2a04e66f6f8d70df32 374 SUPERFAMILY SSF52540 13 354 1.06E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000020 620fc0ca46c24e2a04e66f6f8d70df32 374 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 374 83.292 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MADE_1000020 620fc0ca46c24e2a04e66f6f8d70df32 374 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 13 370 9.4E-96 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 MADE_1000020 620fc0ca46c24e2a04e66f6f8d70df32 374 Pfam PF02463 RecF/RecN/SMC N terminal domain 15 357 3.2E-27 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 SUPERFAMILY SSF55874 410 557 1.11E-29 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 Gene3D G3DSA:3.30.565.10 408 561 6.8E-33 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 SUPERFAMILY SSF47384 309 359 4.12E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 452 558 3.3E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 SMART SM00387 448 560 2.7E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 537 1.8E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 502 1.8E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 516 1.8E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 557 1.8E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1003845 e84c287834b4a87c438c4d8907e4aa96 561 Gene3D G3DSA:1.10.287.130 296 400 1.1E-19 T 13-10-2018 MADE_000001022785 78d39db8ce56ce661d5bbcea400d0e95 164 Pfam PF10688 Bacterial inner membrane protein 4 159 9.2E-27 T 13-10-2018 IPR019629 Uncharacterised protein family HI1736/YgjV MADE_1014265 0ce0fdf9407037625b0f61329c788c61 203 Gene3D G3DSA:3.40.50.300 5 202 1.5E-49 T 13-10-2018 MADE_1014265 0ce0fdf9407037625b0f61329c788c61 203 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 6 199 7.4E-104 T 13-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MADE_1014265 0ce0fdf9407037625b0f61329c788c61 203 SUPERFAMILY SSF52540 3 197 1.67E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014265 0ce0fdf9407037625b0f61329c788c61 203 PIRSF PIRSF005624 1 202 1.5E-48 T 13-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 MADE_1014265 0ce0fdf9407037625b0f61329c788c61 203 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 178 6.6E-39 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain MADE_1014265 0ce0fdf9407037625b0f61329c788c61 203 Hamap MF_01389 Urease accessory protein UreG [ureG]. 4 202 46.593 T 13-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 SMART SM00866 88 244 1.8E-22 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 Gene3D G3DSA:1.10.10.10 1 64 9.4E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 SMART SM00345 8 67 4.4E-21 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 SUPERFAMILY SSF64288 55 246 8.51E-36 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 Gene3D G3DSA:3.40.1410.10 65 213 4.4E-28 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 6.1E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 6.1E-8 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 67 9.7E-18 T 13-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 Pfam PF07702 UTRA domain 88 208 6.6E-28 T 13-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 MADE_1004500 38b53038bb6485ab18728ee3475fb753 251 SUPERFAMILY SSF46785 2 71 1.16E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1010235 e8bb7d0cacb9b8e21dc7d26695c93a66 1019 Pfam PF01526 Tn3 transposase DDE domain 598 997 6.3E-107 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 MADE_1010235 e8bb7d0cacb9b8e21dc7d26695c93a66 1019 Pfam PF13700 Domain of unknown function (DUF4158) 7 168 2.2E-21 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 MADE_1008050 18e5d199cbb2b1ee551078c69bea44d4 277 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 76 1.9E-11 T 13-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 MADE_1008050 18e5d199cbb2b1ee551078c69bea44d4 277 Gene3D G3DSA:3.40.50.10490 95 269 5.1E-25 T 13-10-2018 MADE_1008050 18e5d199cbb2b1ee551078c69bea44d4 277 SUPERFAMILY SSF53697 100 255 2.45E-13 T 13-10-2018 MADE_1008050 18e5d199cbb2b1ee551078c69bea44d4 277 Gene3D G3DSA:1.10.10.10 3 83 3.2E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1008050 18e5d199cbb2b1ee551078c69bea44d4 277 SUPERFAMILY SSF46689 8 84 1.67E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1008050 18e5d199cbb2b1ee551078c69bea44d4 277 Pfam PF01380 SIS domain 121 243 5.2E-9 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 SUPERFAMILY SSF81442 23 529 4.06E-159 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 477 7.2E-139 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 24 528 5.7E-213 T 13-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 Gene3D G3DSA:1.20.210.10 8 536 3.5E-180 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 69 92 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 96 120 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 402 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 296 311 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 355 373 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 138 150 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 170 188 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 250 271 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 22 47 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 341 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 433 454 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 PRINTS PR01165 Cytochrome c oxidase subunit I signature 199 218 3.8E-79 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 252 306 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016540 ecd5078929d926651c45a7135bcc0185 835 SUPERFAMILY SSF81452 573 817 1.96E-10 T 13-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1016275 872fe083a7306e5ef928652642869651 289 ProSitePatterns PS00221 MIP family signature. 68 76 - T 13-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 PRINTS PR00783 Major intrinsic protein family signature 50 74 6.4E-51 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 PRINTS PR00783 Major intrinsic protein family signature 235 255 6.4E-51 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 PRINTS PR00783 Major intrinsic protein family signature 87 106 6.4E-51 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 PRINTS PR00783 Major intrinsic protein family signature 153 171 6.4E-51 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 PRINTS PR00783 Major intrinsic protein family signature 11 30 6.4E-51 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 PRINTS PR00783 Major intrinsic protein family signature 186 208 6.4E-51 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 Pfam PF00230 Major intrinsic protein 6 252 6.0E-63 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 TIGRFAM TIGR00861 MIP: MIP family channel proteins 15 252 8.8E-67 T 13-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 Gene3D G3DSA:1.20.1080.10 5 260 1.1E-98 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MADE_1016275 872fe083a7306e5ef928652642869651 289 SUPERFAMILY SSF81338 9 257 5.63E-75 T 13-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 MADE_1003870 c97b1e6e241007afdf66071dafaa0092 882 SUPERFAMILY SSF56935 39 882 5.86E-66 T 13-10-2018 MADE_1003870 c97b1e6e241007afdf66071dafaa0092 882 Gene3D G3DSA:2.40.170.20 323 882 4.8E-26 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1003870 c97b1e6e241007afdf66071dafaa0092 882 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 152 1.3E-6 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1003870 c97b1e6e241007afdf66071dafaa0092 882 Gene3D G3DSA:2.170.130.10 29 164 4.0E-7 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1003870 c97b1e6e241007afdf66071dafaa0092 882 Pfam PF00593 TonB dependent receptor 424 854 5.7E-19 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1008965 fd7ac89c8a22cb3a1a138dd86a0cc57e 223 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 119 210 2.5E-22 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MADE_1008965 fd7ac89c8a22cb3a1a138dd86a0cc57e 223 SMART SM00702 30 210 2.3E-20 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MADE_1008965 fd7ac89c8a22cb3a1a138dd86a0cc57e 223 Gene3D G3DSA:2.60.120.620 18 214 1.2E-47 T 13-10-2018 MADE_1012230 c05d825de9824beb658aee2b762c9ab0 236 SUPERFAMILY SSF53067 1 100 1.12E-28 T 13-10-2018 MADE_1012230 c05d825de9824beb658aee2b762c9ab0 236 Pfam PF00814 Glycoprotease family 28 202 6.8E-26 T 13-10-2018 IPR000905 Gcp-like domain MADE_1012230 c05d825de9824beb658aee2b762c9ab0 236 Gene3D G3DSA:3.30.420.40 94 193 1.8E-70 T 13-10-2018 MADE_1012230 c05d825de9824beb658aee2b762c9ab0 236 Gene3D G3DSA:3.30.420.40 3 227 1.8E-70 T 13-10-2018 MADE_1012230 c05d825de9824beb658aee2b762c9ab0 236 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 224 3.6E-59 T 13-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 MADE_1012230 c05d825de9824beb658aee2b762c9ab0 236 SUPERFAMILY SSF53067 112 222 7.38E-19 T 13-10-2018 MADE_1001945 9982dbc8d5050c2cf1c33de0e55f8d43 123 SUPERFAMILY SSF55008 14 80 3.76E-5 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 MADE_1014400 950d68db101f7079f66dd3b661259d0c 345 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 3 317 2.5E-102 T 13-10-2018 IPR010148 CRISPR-associated protein, CT1975 MADE_1014400 950d68db101f7079f66dd3b661259d0c 345 Pfam PF09344 CT1975-like protein 5 330 7.7E-102 T 13-10-2018 IPR010148 CRISPR-associated protein, CT1975 MADE_1016390 1ae688d7470487b26d096e45283fcec8 253 Gene3D G3DSA:3.40.50.10610 32 124 1.7E-34 T 13-10-2018 MADE_1016390 1ae688d7470487b26d096e45283fcec8 253 Gene3D G3DSA:3.40.50.10610 125 253 8.0E-48 T 13-10-2018 MADE_1016390 1ae688d7470487b26d096e45283fcec8 253 Pfam PF03783 Curli production assembly/transport component CsgG 44 252 5.0E-79 T 13-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 MADE_1018405 1c991fc93fe0d8c7867a4a8c6e3f6f0f 60 Gene3D G3DSA:1.10.1660.10 2 59 3.0E-6 T 13-10-2018 MADE_1018405 1c991fc93fe0d8c7867a4a8c6e3f6f0f 60 SUPERFAMILY SSF46955 3 53 2.38E-5 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1013965 b462ce0f9c69872ceeabfb5a310ca936 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.7E-44 T 13-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1013965 b462ce0f9c69872ceeabfb5a310ca936 144 Gene3D G3DSA:3.100.10.10 69 144 4.4E-14 T 13-10-2018 MADE_1013965 b462ce0f9c69872ceeabfb5a310ca936 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 5.3E-29 T 13-10-2018 IPR021131 Ribosomal protein L18e/L15P MADE_1013965 b462ce0f9c69872ceeabfb5a310ca936 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 18.483 T 13-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 MADE_1013965 b462ce0f9c69872ceeabfb5a310ca936 144 SUPERFAMILY SSF52080 4 143 5.89E-44 T 13-10-2018 IPR036227 Ribosomal L18e/L15P superfamily MADE_1011855 7ca964807a834c0cc266e553e453a562 336 SUPERFAMILY SSF56349 83 331 7.06E-46 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1011855 7ca964807a834c0cc266e553e453a562 336 Gene3D G3DSA:1.10.443.10 177 336 2.4E-29 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1011855 7ca964807a834c0cc266e553e453a562 336 Pfam PF00589 Phage integrase family 176 326 6.3E-25 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 361 24.53 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 10 170 2.5E-30 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 SMART SM00864 10 203 4.0E-52 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 Pfam PF12327 FtsZ family, C-terminal domain 220 315 1.8E-11 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 PRINTS PR00423 Cell division protein FtsZ signature 96 116 1.1E-19 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 PRINTS PR00423 Cell division protein FtsZ signature 210 231 1.1E-19 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 PRINTS PR00423 Cell division protein FtsZ signature 187 209 1.1E-19 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 PRINTS PR00423 Cell division protein FtsZ signature 124 145 1.1E-19 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 SUPERFAMILY SSF52490 10 203 1.02E-46 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 SUPERFAMILY SSF55307 203 318 9.39E-22 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 Gene3D G3DSA:3.40.50.1440 7 315 2.0E-79 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 SMART SM00865 205 324 2.4E-5 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 MADE_1007840 d953256e8af3c9c9a854a12b0050dc6e 361 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 104 110 - T 13-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 MADE_1014440 13922618ff59f28fb99088961dfc6f05 378 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 9 367 4.0E-88 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MADE_1014440 13922618ff59f28fb99088961dfc6f05 378 Pfam PF01979 Amidohydrolase family 52 376 4.9E-20 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_1014440 13922618ff59f28fb99088961dfc6f05 378 SUPERFAMILY SSF51556 55 348 3.74E-94 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1014440 13922618ff59f28fb99088961dfc6f05 378 SUPERFAMILY SSF51338 4 377 9.87E-7 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1014440 13922618ff59f28fb99088961dfc6f05 378 PIRSF PIRSF038994 1 378 8.4E-104 T 13-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 MADE_1014440 13922618ff59f28fb99088961dfc6f05 378 Gene3D G3DSA:3.20.20.140 56 342 7.1E-107 T 13-10-2018 MADE_1014440 13922618ff59f28fb99088961dfc6f05 378 Gene3D G3DSA:2.30.40.10 9 374 7.1E-107 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 Pfam PF03243 Alkylmercury lyase 77 197 1.1E-37 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 SUPERFAMILY SSF160387 81 205 2.48E-39 T 13-10-2018 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 PRINTS PR01699 Organomercurial lyase signature 32 45 1.9E-19 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 PRINTS PR01699 Organomercurial lyase signature 92 101 1.9E-19 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 PRINTS PR01699 Organomercurial lyase signature 117 128 1.9E-19 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 PRINTS PR01699 Organomercurial lyase signature 163 178 1.9E-19 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 PRINTS PR01699 Organomercurial lyase signature 75 89 1.9E-19 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 Pfam PF12324 Helix-turn-helix domain of alkylmercury lyase 15 75 4.1E-14 T 13-10-2018 IPR024259 Alkylmercury lyase, helix-turn-helix domain MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 Gene3D G3DSA:2.40.10.490 4 208 2.0E-68 T 13-10-2018 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 PIRSF PIRSF001458 2 208 1.7E-64 T 13-10-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 MADE_1005595 b5e1c8b5e61de32d40d8da68daf0dde1 211 SUPERFAMILY SSF46785 21 80 7.07E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1003790 e6453cc3d85de19dbc8bfc1f12045f67 447 Gene3D G3DSA:3.40.720.10 68 433 7.0E-104 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 MADE_1003790 e6453cc3d85de19dbc8bfc1f12045f67 447 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 68 386 3.2E-61 T 13-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 MADE_1003790 e6453cc3d85de19dbc8bfc1f12045f67 447 SUPERFAMILY SSF53649 64 427 2.29E-77 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MADE_1003790 e6453cc3d85de19dbc8bfc1f12045f67 447 Gene3D G3DSA:3.30.1360.180 283 384 7.0E-104 T 13-10-2018 MADE_1014110 eadd28d0ce006a8e93549b1135d6b2ea 226 Pfam PF07308 Protein of unknown function (DUF1456) 3 70 5.6E-21 T 13-10-2018 IPR009921 Domain of unknown function DUF1456 MADE_1014110 eadd28d0ce006a8e93549b1135d6b2ea 226 Pfam PF07308 Protein of unknown function (DUF1456) 88 154 2.2E-21 T 13-10-2018 IPR009921 Domain of unknown function DUF1456 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 Pfam PF02253 Phospholipase A1 75 336 1.4E-88 T 13-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 Gene3D G3DSA:2.40.230.10 76 338 4.0E-82 T 13-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 PRINTS PR01486 Bacterial phospholipase A1 protein signature 210 228 4.9E-26 T 13-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 PRINTS PR01486 Bacterial phospholipase A1 protein signature 165 184 4.9E-26 T 13-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 PRINTS PR01486 Bacterial phospholipase A1 protein signature 195 209 4.9E-26 T 13-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 PRINTS PR01486 Bacterial phospholipase A1 protein signature 121 138 4.9E-26 T 13-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 PRINTS PR01486 Bacterial phospholipase A1 protein signature 309 329 4.9E-26 T 13-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1005285 5c480c47b12ccbe0787cb424b2430c67 339 SUPERFAMILY SSF56931 78 336 4.84E-85 T 13-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 MADE_1001100 98c359273e09c5d2b7f8a66491f765f1 445 PRINTS PR01035 Tetracycline resistance protein signature 18 34 5.3E-5 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MADE_1001100 98c359273e09c5d2b7f8a66491f765f1 445 PRINTS PR01035 Tetracycline resistance protein signature 99 120 5.3E-5 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MADE_1001100 98c359273e09c5d2b7f8a66491f765f1 445 PRINTS PR01035 Tetracycline resistance protein signature 270 291 5.3E-5 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 MADE_1001100 98c359273e09c5d2b7f8a66491f765f1 445 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 79 - T 13-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 MADE_1001100 98c359273e09c5d2b7f8a66491f765f1 445 Pfam PF07690 Major Facilitator Superfamily 13 339 4.7E-39 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1001100 98c359273e09c5d2b7f8a66491f765f1 445 SUPERFAMILY SSF103473 7 383 9.16E-57 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1001100 98c359273e09c5d2b7f8a66491f765f1 445 Gene3D G3DSA:1.20.1250.20 3 386 1.7E-71 T 13-10-2018 MADE_000001023480 d40660e5d227d8b6ee6b2c7442626844 219 SUPERFAMILY SSF52833 1 80 2.2E-24 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_000001023480 d40660e5d227d8b6ee6b2c7442626844 219 Gene3D G3DSA:1.20.1050.10 84 191 6.1E-81 T 13-10-2018 MADE_000001023480 d40660e5d227d8b6ee6b2c7442626844 219 Pfam PF00043 Glutathione S-transferase, C-terminal domain 130 192 1.8E-6 T 13-10-2018 IPR004046 Glutathione S-transferase, C-terminal MADE_000001023480 d40660e5d227d8b6ee6b2c7442626844 219 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 77 1.0E-14 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 MADE_000001023480 d40660e5d227d8b6ee6b2c7442626844 219 Gene3D G3DSA:3.40.30.10 2 201 6.1E-81 T 13-10-2018 MADE_000001023480 d40660e5d227d8b6ee6b2c7442626844 219 SUPERFAMILY SSF47616 74 199 1.16E-32 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily MADE_1019115 ece79eccaa61b8ce32da53c4b6b44a7e 265 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 24 265 1.7E-33 T 13-10-2018 IPR005519 Acid phosphatase, class B-like MADE_1019115 ece79eccaa61b8ce32da53c4b6b44a7e 265 SUPERFAMILY SSF56784 76 265 6.61E-22 T 13-10-2018 IPR036412 HAD-like superfamily MADE_1019115 ece79eccaa61b8ce32da53c4b6b44a7e 265 Gene3D G3DSA:3.40.50.1000 29 265 1.4E-49 T 13-10-2018 IPR023214 HAD superfamily MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 40 482 1.8E-153 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 441 462 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 105 129 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 31 56 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 178 196 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 410 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 349 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 363 381 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 78 101 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 148 160 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 207 226 2.9E-122 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 SUPERFAMILY SSF81442 28 536 7.72E-194 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 32 536 6.2E-214 T 13-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MADE_1020100 2b58818e4e2f6158fbcb9e0ce9e0918e 537 Gene3D G3DSA:1.20.210.10 19 537 6.3E-218 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1003380 e9525e2712c9e4b1736085c0cbb418a9 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 156 1.1E-69 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MADE_1003380 e9525e2712c9e4b1736085c0cbb418a9 157 Pfam PF02542 YgbB family 1 155 3.7E-66 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MADE_1003380 e9525e2712c9e4b1736085c0cbb418a9 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 13-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MADE_1003380 e9525e2712c9e4b1736085c0cbb418a9 157 Gene3D G3DSA:3.30.1330.50 1 157 3.0E-68 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MADE_1003380 e9525e2712c9e4b1736085c0cbb418a9 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 35.596 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MADE_1003380 e9525e2712c9e4b1736085c0cbb418a9 157 SUPERFAMILY SSF69765 1 156 4.97E-65 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 MADE_1002945 c52ff2c5e85117a012b171529365d677 142 Gene3D G3DSA:3.10.180.10 1 136 5.2E-35 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1002945 c52ff2c5e85117a012b171529365d677 142 SUPERFAMILY SSF54593 5 134 1.2E-20 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1003925 38f5bebd89d6c0d84880e48800266cff 404 Pfam PF07995 Glucose / Sorbosone dehydrogenase 75 391 4.4E-74 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase MADE_1003925 38f5bebd89d6c0d84880e48800266cff 404 Gene3D G3DSA:2.120.10.30 43 397 1.2E-66 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1003925 38f5bebd89d6c0d84880e48800266cff 404 SUPERFAMILY SSF50952 76 398 6.15E-23 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 MADE_1011020 fd715e03dd11b81ec1282bfc1884b025 93 Gene3D G3DSA:3.30.2310.20 1 90 1.1E-16 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1011020 fd715e03dd11b81ec1282bfc1884b025 93 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 1 89 9.1E-13 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1011020 fd715e03dd11b81ec1282bfc1884b025 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 2 89 1.9E-14 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1009025 0aed03ca660cb977364e026f4584835e 384 Gene3D G3DSA:2.120.10.30 72 384 9.8E-67 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like MADE_1009025 0aed03ca660cb977364e026f4584835e 384 SUPERFAMILY SSF63829 40 380 6.98E-42 T 13-10-2018 MADE_1009025 0aed03ca660cb977364e026f4584835e 384 Pfam PF03088 Strictosidine synthase 171 264 3.5E-22 T 13-10-2018 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 MADE_000001023080 769249835f45a05137c1054b37cfc3a3 226 Gene3D G3DSA:3.30.420.10 27 204 1.2E-28 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_000001023080 769249835f45a05137c1054b37cfc3a3 226 SMART SM00479 32 205 1.3E-14 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_000001023080 769249835f45a05137c1054b37cfc3a3 226 Pfam PF00929 Exonuclease 35 196 1.0E-12 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III MADE_000001023080 769249835f45a05137c1054b37cfc3a3 226 SUPERFAMILY SSF53098 30 203 9.83E-28 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1008155 1fd352906178b0b5eb5e375cdb618ea9 226 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 63 172 2.0E-14 T 13-10-2018 IPR010319 Transglutaminase-like cysteine peptidase, predicted MADE_1008155 1fd352906178b0b5eb5e375cdb618ea9 226 Gene3D G3DSA:3.10.620.30 26 217 5.2E-74 T 13-10-2018 MADE_1012950 7259e0260531942f907171ee6407c34c 313 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 109 280 2.5E-54 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1012950 7259e0260531942f907171ee6407c34c 313 Pfam PF07549 SecD/SecF GG Motif 32 58 3.1E-9 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site MADE_1012950 7259e0260531942f907171ee6407c34c 313 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 39 283 3.1E-84 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MADE_1012950 7259e0260531942f907171ee6407c34c 313 Gene3D G3DSA:1.20.1640.10 96 296 3.6E-13 T 13-10-2018 MADE_1012950 7259e0260531942f907171ee6407c34c 313 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 27.791 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 MADE_1012950 7259e0260531942f907171ee6407c34c 313 SUPERFAMILY SSF82866 73 290 2.62E-41 T 13-10-2018 MADE_1012950 7259e0260531942f907171ee6407c34c 313 Pfam PF02355 Protein export membrane protein 109 290 8.1E-68 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial MADE_1012950 7259e0260531942f907171ee6407c34c 313 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 3.0E-32 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1012950 7259e0260531942f907171ee6407c34c 313 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 3.0E-32 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1012950 7259e0260531942f907171ee6407c34c 313 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 3.0E-32 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1012950 7259e0260531942f907171ee6407c34c 313 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 3.0E-32 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial MADE_1008435 351d5cbe18977014169c7efc3136c190 266 Gene3D G3DSA:1.10.12.10 204 266 3.2E-23 T 13-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal MADE_1008435 351d5cbe18977014169c7efc3136c190 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 260 1.0E-51 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MADE_1008435 351d5cbe18977014169c7efc3136c190 266 Gene3D G3DSA:3.90.226.10 2 203 4.9E-61 T 13-10-2018 MADE_1008435 351d5cbe18977014169c7efc3136c190 266 SUPERFAMILY SSF52096 3 259 5.15E-69 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_000001023500 4a02c40cdc45b4c661f2c3f732fa0ad2 250 Gene3D G3DSA:3.40.50.150 17 248 1.8E-60 T 13-10-2018 MADE_000001023500 4a02c40cdc45b4c661f2c3f732fa0ad2 250 SUPERFAMILY SSF53335 17 233 1.17E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_000001023500 4a02c40cdc45b4c661f2c3f732fa0ad2 250 Pfam PF08241 Methyltransferase domain 73 167 1.5E-17 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MADE_000001023500 4a02c40cdc45b4c661f2c3f732fa0ad2 250 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 17 243 8.7E-73 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MADE_000001023500 4a02c40cdc45b4c661f2c3f732fa0ad2 250 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 17 249 32.849 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 MADE_1000495 395909b8870d1f46832e6a646ffc5fa4 396 Gene3D G3DSA:1.20.1600.10 25 393 8.7E-12 T 13-10-2018 MADE_1000495 395909b8870d1f46832e6a646ffc5fa4 396 SUPERFAMILY SSF56954 67 353 9.94E-13 T 13-10-2018 MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 13-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 Gene3D G3DSA:3.30.190.20 21 225 3.6E-82 T 13-10-2018 MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 SUPERFAMILY SSF56808 6 225 6.15E-82 T 13-10-2018 IPR023674 Ribosomal protein L1-like MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.384 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 2.4E-106 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 Gene3D G3DSA:3.40.50.790 68 159 3.6E-82 T 13-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 PIRSF PIRSF002155 1 227 6.1E-80 T 13-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_000001023315 8b638075d06a0c27634883bd0c56d726 231 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 2.4E-55 T 13-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein MADE_1013160 d6731224ee55d5d8d59fc8df1d93e6fc 333 Gene3D G3DSA:3.20.20.370 1 329 5.2E-26 T 13-10-2018 MADE_1013160 d6731224ee55d5d8d59fc8df1d93e6fc 333 SUPERFAMILY SSF88713 37 318 4.17E-14 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 MADE_1000070 65b89af334eeb8f8fafbbabffc5d2d95 212 Pfam PF01926 50S ribosome-binding GTPase 26 144 8.8E-21 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1000070 65b89af334eeb8f8fafbbabffc5d2d95 212 Gene3D G3DSA:3.40.50.300 2 204 1.0E-54 T 13-10-2018 MADE_1000070 65b89af334eeb8f8fafbbabffc5d2d95 212 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 191 3.5E-72 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MADE_1000070 65b89af334eeb8f8fafbbabffc5d2d95 212 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 195 26.875 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 MADE_1000070 65b89af334eeb8f8fafbbabffc5d2d95 212 SUPERFAMILY SSF52540 16 194 1.57E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009920 88dd2c1fa67e6a48a679153fc4d95350 624 Gene3D G3DSA:1.10.510.10 43 325 1.1E-22 T 13-10-2018 MADE_1009920 88dd2c1fa67e6a48a679153fc4d95350 624 Pfam PF00069 Protein kinase domain 45 266 6.6E-15 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MADE_1009920 88dd2c1fa67e6a48a679153fc4d95350 624 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 51 73 - T 13-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 MADE_1009920 88dd2c1fa67e6a48a679153fc4d95350 624 SUPERFAMILY SSF56112 44 309 3.96E-33 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1009920 88dd2c1fa67e6a48a679153fc4d95350 624 SMART SM00220 45 312 1.3E-7 T 13-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 SUPERFAMILY SSF56534 4 248 3.01E-99 T 13-10-2018 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 Gene3D G3DSA:1.10.800.10 1 266 7.0E-102 T 13-10-2018 IPR036951 Aromatic amino acid hydroxylase superfamily GO:0004497|GO:0005506|GO:0009072|GO:0055114 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 139 158 2.9E-10 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 211 230 2.9E-10 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 75 97 2.9E-10 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 179 197 2.9E-10 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 118 129 - T 13-10-2018 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 11 256 1.1E-104 T 13-10-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|KEGG: 00790+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 MADE_1006175 cfb70ec018102a02171a9e79dbad348b 266 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 7 232 5.3E-50 T 13-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 Pfam PF03705 CheR methyltransferase, all-alpha domain 11 57 5.7E-9 T 13-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 Gene3D G3DSA:3.40.50.150 75 275 5.3E-59 T 13-10-2018 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 SUPERFAMILY SSF53335 76 271 8.81E-47 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 Pfam PF01739 CheR methyltransferase, SAM binding domain 76 269 1.6E-62 T 13-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 Gene3D G3DSA:1.10.155.10 2 74 1.7E-9 T 13-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 8.1E-41 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 PRINTS PR00996 Glutamate methyltransferase family signature 69 81 8.1E-41 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 PRINTS PR00996 Glutamate methyltransferase family signature 232 255 8.1E-41 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 PRINTS PR00996 Glutamate methyltransferase family signature 213 227 8.1E-41 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 PRINTS PR00996 Glutamate methyltransferase family signature 144 160 8.1E-41 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 PRINTS PR00996 Glutamate methyltransferase family signature 30 43 8.1E-41 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 SUPERFAMILY SSF47757 6 75 3.01E-14 T 13-10-2018 MADE_1005700 c60b6c4e2cdedf7936786e41cc6a19dd 276 SMART SM00138 8 273 4.6E-95 T 13-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 Gene3D G3DSA:2.60.40.2380 39 187 2.6E-16 T 13-10-2018 MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 Pfam PF07695 7TM diverse intracellular signalling 191 392 4.6E-38 T 13-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 Pfam PF07696 7TMR-DISM extracellular 2 45 179 7.5E-21 T 13-10-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 Gene3D G3DSA:3.30.70.270 449 625 2.9E-54 T 13-10-2018 MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 Pfam PF00990 Diguanylate cyclase, GGDEF domain 464 622 3.3E-44 T 13-10-2018 IPR000160 GGDEF domain MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 SUPERFAMILY SSF55073 468 624 2.28E-44 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 459 625 4.4E-50 T 13-10-2018 IPR000160 GGDEF domain MADE_1002835 df386ce71bd01e103577c8d485137bd9 632 SMART SM00267 452 626 1.1E-62 T 13-10-2018 IPR000160 GGDEF domain MADE_1008625 d2182839361a39ee2bdc3a7f046f2d06 211 Pfam PF12804 MobA-like NTP transferase domain 10 125 1.8E-25 T 13-10-2018 IPR025877 MobA-like NTP transferase MADE_1008625 d2182839361a39ee2bdc3a7f046f2d06 211 Gene3D G3DSA:3.90.550.10 11 209 5.5E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008625 d2182839361a39ee2bdc3a7f046f2d06 211 SUPERFAMILY SSF53448 9 207 4.06E-25 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1015380 f171c86a6710d5915ebbe9a178971c6b 611 Pfam PF05960 Bacterial protein of unknown function (DUF885) 63 601 3.5E-155 T 13-10-2018 IPR010281 Protein of unknown function DUF885 MADE_1013815 5cc88f25239534bbc21b0f9388a2f375 293 Gene3D G3DSA:3.90.550.10 1 293 8.7E-85 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013815 5cc88f25239534bbc21b0f9388a2f375 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 3 287 4.3E-149 T 13-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 MADE_1013815 5cc88f25239534bbc21b0f9388a2f375 293 Pfam PF00483 Nucleotidyl transferase 3 239 3.0E-68 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MADE_1013815 5cc88f25239534bbc21b0f9388a2f375 293 SUPERFAMILY SSF53448 2 287 5.63E-89 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1018330 8aa3ff3f6ef30e604e758722d5ea83b0 294 Pfam PF03631 Virulence factor BrkB 30 276 1.1E-55 T 13-10-2018 IPR017039 Virulence factor BrkB MADE_1018330 8aa3ff3f6ef30e604e758722d5ea83b0 294 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 24 277 7.3E-86 T 13-10-2018 IPR017039 Virulence factor BrkB MADE_1018330 8aa3ff3f6ef30e604e758722d5ea83b0 294 PIRSF PIRSF035875 7 294 2.5E-60 T 13-10-2018 IPR017039 Virulence factor BrkB MADE_1018330 8aa3ff3f6ef30e604e758722d5ea83b0 294 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 6 294 23.964 T 13-10-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial MADE_1004800 8d58da8d725278a8f0ea139e5ae1de24 428 Gene3D G3DSA:1.25.40.10 152 290 9.2E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1004800 8d58da8d725278a8f0ea139e5ae1de24 428 SUPERFAMILY SSF48452 162 272 3.16E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1004800 8d58da8d725278a8f0ea139e5ae1de24 428 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 6 111 2.8E-13 T 13-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI MADE_1004280 daa9d4cd6f2d90503d0e978117d8ceff 143 Pfam PF01152 Bacterial-like globin 28 137 1.1E-11 T 13-10-2018 IPR001486 Truncated hemoglobin GO:0019825 MADE_1004280 daa9d4cd6f2d90503d0e978117d8ceff 143 Gene3D G3DSA:1.10.490.10 15 142 3.1E-29 T 13-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 MADE_1004280 daa9d4cd6f2d90503d0e978117d8ceff 143 SUPERFAMILY SSF46458 28 138 1.32E-23 T 13-10-2018 IPR009050 Globin-like superfamily MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 Gene3D G3DSA:1.10.10.60 378 441 5.3E-10 T 13-10-2018 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 SMART SM00382 149 293 3.0E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 SUPERFAMILY SSF52172 1 173 1.99E-40 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 Gene3D G3DSA:3.40.50.2300 4 119 2.9E-32 T 13-10-2018 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 Pfam PF02954 Bacterial regulatory protein, Fis family 399 435 3.1E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 Gene3D G3DSA:1.10.8.60 301 377 1.3E-24 T 13-10-2018 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 SMART SM00448 4 115 4.0E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 SUPERFAMILY SSF46689 342 435 5.38E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 342 351 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 Pfam PF00072 Response regulator receiver domain 6 114 4.2E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 SUPERFAMILY SSF52540 137 370 2.09E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 Gene3D G3DSA:3.40.50.300 120 300 1.2E-63 T 13-10-2018 MADE_1005890 71c38f58ba2ca44cbc53752d9e84a188 445 Pfam PF00158 Sigma-54 interaction domain 133 296 5.5E-66 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 MADE_1019345 b82bf11ae7ae9023677d3408f2ca40c5 197 SUPERFAMILY SSF53448 1 173 2.12E-21 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019345 b82bf11ae7ae9023677d3408f2ca40c5 197 Gene3D G3DSA:3.90.550.10 1 181 1.7E-30 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019345 b82bf11ae7ae9023677d3408f2ca40c5 197 Pfam PF12804 MobA-like NTP transferase domain 5 107 2.1E-23 T 13-10-2018 IPR025877 MobA-like NTP transferase MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 Pfam PF00571 CBS domain 203 259 0.0022 T 13-10-2018 IPR000644 CBS domain MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 Pfam PF00571 CBS domain 270 322 0.0024 T 13-10-2018 IPR000644 CBS domain MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 Gene3D G3DSA:3.40.50.10490 4 197 1.2E-67 T 13-10-2018 MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 PIRSF PIRSF004692 1 326 2.4E-131 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 Gene3D G3DSA:3.10.580.10 198 323 5.9E-41 T 13-10-2018 MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 Pfam PF01380 SIS domain 43 174 1.5E-32 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 47 315 1.2E-108 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 MADE_1004210 8c7f0cbc26615eccd23ea501adaf1aba 326 SUPERFAMILY SSF53697 8 321 7.12E-67 T 13-10-2018 MADE_1019185 749f66714e88bcee0a836394f5852c8d 188 SUPERFAMILY SSF101874 19 187 2.62E-55 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MADE_1019185 749f66714e88bcee0a836394f5852c8d 188 Gene3D G3DSA:2.40.128.110 20 188 4.6E-54 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MADE_1019185 749f66714e88bcee0a836394f5852c8d 188 SMART SM00867 21 186 1.0E-69 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MADE_1019185 749f66714e88bcee0a836394f5852c8d 188 Pfam PF04264 YceI-like domain 22 184 3.1E-40 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MADE_1011965 d6b8286d0544766531320886e982b118 424 Gene3D G3DSA:2.120.10.80 14 254 4.7E-30 T 13-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 MADE_1011965 d6b8286d0544766531320886e982b118 424 Pfam PF13964 Kelch motif 119 167 2.1E-8 T 13-10-2018 MADE_1011965 d6b8286d0544766531320886e982b118 424 SUPERFAMILY SSF117281 71 363 3.66E-34 T 13-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 MADE_1013995 ec3b6d07bc9acab02287a025627e2168 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 3.2E-27 T 13-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1013995 ec3b6d07bc9acab02287a025627e2168 101 Gene3D G3DSA:4.10.830.10 41 101 8.1E-24 T 13-10-2018 MADE_1013995 ec3b6d07bc9acab02287a025627e2168 101 SUPERFAMILY SSF57716 2 101 1.5E-39 T 13-10-2018 MADE_1013995 ec3b6d07bc9acab02287a025627e2168 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 13-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1013995 ec3b6d07bc9acab02287a025627e2168 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.307 T 13-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid MADE_1007265 cf110def4407a406e549117d20687ba2 325 Pfam PF08241 Methyltransferase domain 117 206 4.3E-23 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 MADE_1007265 cf110def4407a406e549117d20687ba2 325 SUPERFAMILY SSF53335 80 260 2.3E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1007265 cf110def4407a406e549117d20687ba2 325 Gene3D G3DSA:3.40.50.150 81 273 9.9E-32 T 13-10-2018 MADE_1013890 c373c1a31be50740d481c50b0403fc32 447 Gene3D G3DSA:3.40.50.300 24 275 1.1E-6 T 13-10-2018 MADE_1013890 c373c1a31be50740d481c50b0403fc32 447 SUPERFAMILY SSF52540 22 224 5.31E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004240 96446c6ac1973e5479a3b87362505b16 102 SUPERFAMILY SSF52091 6 101 1.41E-12 T 13-10-2018 IPR036513 STAS domain superfamily MADE_1004240 96446c6ac1973e5479a3b87362505b16 102 Pfam PF13466 STAS domain 12 94 3.7E-15 T 13-10-2018 IPR002645 STAS domain MADE_1004240 96446c6ac1973e5479a3b87362505b16 102 Gene3D G3DSA:3.30.750.24 5 102 1.0E-13 T 13-10-2018 IPR036513 STAS domain superfamily MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.9E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.9E-9 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 1.4E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 163 201 7.7E-6 T 13-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 Gene3D G3DSA:1.10.357.10 63 203 4.4E-23 T 13-10-2018 MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 SUPERFAMILY SSF46689 4 86 2.69E-19 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_000001021325 edbb7e7cc95a03af47b7efa326598ac2 204 Gene3D G3DSA:1.10.10.60 4 60 5.9E-21 T 13-10-2018 MADE_000001023660 44fe387a4da08637a15174cc111c368f 314 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 47 289 1.0E-41 T 13-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 MADE_000001023660 44fe387a4da08637a15174cc111c368f 314 SUPERFAMILY SSF51998 52 265 2.56E-39 T 13-10-2018 MADE_000001023660 44fe387a4da08637a15174cc111c368f 314 Gene3D G3DSA:3.20.70.20 53 263 1.8E-11 T 13-10-2018 MADE_1012190 901808a266d6ff8aa7420e12b0ca4b23 222 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 19 211 1.6E-43 T 13-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 MADE_1012190 901808a266d6ff8aa7420e12b0ca4b23 222 Gene3D G3DSA:3.90.850.10 1 221 8.2E-64 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MADE_1012190 901808a266d6ff8aa7420e12b0ca4b23 222 SUPERFAMILY SSF56529 14 220 9.29E-60 T 13-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 MADE_1006090 a7db7c54cd0025c4510da084c7eea8ff 445 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 16 417 4.8E-130 T 13-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition MADE_1006090 a7db7c54cd0025c4510da084c7eea8ff 445 SUPERFAMILY SSF55729 218 388 1.7E-31 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1004080 ec8398c649e1ddbb2527c72a0ba7c4a6 223 Pfam PF14518 Iron-containing redox enzyme 39 206 5.1E-27 T 13-10-2018 MADE_1004080 ec8398c649e1ddbb2527c72a0ba7c4a6 223 SUPERFAMILY SSF48613 1 214 7.79E-65 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MADE_1004080 ec8398c649e1ddbb2527c72a0ba7c4a6 223 Gene3D G3DSA:1.20.910.10 3 220 1.4E-59 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MADE_1004080 ec8398c649e1ddbb2527c72a0ba7c4a6 223 SMART SM01236 73 170 1.3E-8 T 13-10-2018 MADE_1018120 1fe148b0992f9e7225fcefea98452a82 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 12 325 5.3E-78 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MADE_1006765 d69e442b17fc366d4a290b507be4b696 617 Pfam PF05960 Bacterial protein of unknown function (DUF885) 65 607 7.2E-181 T 13-10-2018 IPR010281 Protein of unknown function DUF885 MADE_1014205 fc1b50a2fa05f36bc3c2f69696a97a5b 374 Gene3D G3DSA:3.40.50.720 150 337 1.0E-150 T 13-10-2018 MADE_1014205 fc1b50a2fa05f36bc3c2f69696a97a5b 374 Pfam PF00107 Zinc-binding dehydrogenase 181 262 4.5E-9 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1014205 fc1b50a2fa05f36bc3c2f69696a97a5b 374 SUPERFAMILY SSF50129 16 182 1.99E-21 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1014205 fc1b50a2fa05f36bc3c2f69696a97a5b 374 Gene3D G3DSA:3.90.180.10 6 371 1.0E-150 T 13-10-2018 MADE_1014205 fc1b50a2fa05f36bc3c2f69696a97a5b 374 SUPERFAMILY SSF51735 144 268 3.34E-18 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1008395 543530b73861d7d3284a94a96376931e 267 Gene3D G3DSA:3.40.50.1820 2 265 2.0E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1008395 543530b73861d7d3284a94a96376931e 267 SUPERFAMILY SSF53474 10 260 3.72E-29 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1008395 543530b73861d7d3284a94a96376931e 267 Pfam PF12697 Alpha/beta hydrolase family 10 256 1.1E-15 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 MADE_1004920 035c632c320142651a2530cafd771737 215 Gene3D G3DSA:3.40.630.30 22 214 4.9E-17 T 13-10-2018 MADE_1004920 035c632c320142651a2530cafd771737 215 Pfam PF00583 Acetyltransferase (GNAT) family 65 164 5.0E-5 T 13-10-2018 IPR000182 GNAT domain MADE_1004920 035c632c320142651a2530cafd771737 215 SUPERFAMILY SSF55729 24 183 1.14E-14 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1019295 5858bbcc8c0637406a1ebbbf23665b4b 259 Gene3D G3DSA:3.40.190.10 102 208 1.5E-66 T 13-10-2018 MADE_1019295 5858bbcc8c0637406a1ebbbf23665b4b 259 Gene3D G3DSA:3.40.190.10 27 246 1.5E-66 T 13-10-2018 MADE_1019295 5858bbcc8c0637406a1ebbbf23665b4b 259 Pfam PF13531 Bacterial extracellular solute-binding protein 23 247 9.0E-47 T 13-10-2018 MADE_1019295 5858bbcc8c0637406a1ebbbf23665b4b 259 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 28 245 4.7E-57 T 13-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MADE_1019295 5858bbcc8c0637406a1ebbbf23665b4b 259 SUPERFAMILY SSF53850 21 249 5.44E-56 T 13-10-2018 MADE_1019295 5858bbcc8c0637406a1ebbbf23665b4b 259 PIRSF PIRSF004846 1 250 7.9E-62 T 13-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MADE_1002055 1b83791de9e33aa69f65426612a389ee 294 SUPERFAMILY SSF103481 39 137 1.7E-14 T 13-10-2018 MADE_1002055 1b83791de9e33aa69f65426612a389ee 294 Pfam PF00892 EamA-like transporter family 148 286 3.4E-11 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1002055 1b83791de9e33aa69f65426612a389ee 294 Pfam PF00892 EamA-like transporter family 1 132 6.5E-21 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 MADE_1002055 1b83791de9e33aa69f65426612a389ee 294 SUPERFAMILY SSF103481 185 289 3.79E-8 T 13-10-2018 MADE_000001022205 2e83f20901af5123db7b321903a11d61 157 Gene3D G3DSA:3.20.160.10 32 155 7.6E-46 T 13-10-2018 IPR038604 Type III effector HopJ superfamily MADE_000001022205 2e83f20901af5123db7b321903a11d61 157 Pfam PF08888 HopJ type III effector protein 45 152 7.4E-44 T 13-10-2018 IPR014984 HopJ type III effector protein MADE_1013425 e7f1f3bf1760f1aa7fdfc9e59669bb28 335 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 9 335 53.741 T 13-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 MADE_1013425 e7f1f3bf1760f1aa7fdfc9e59669bb28 335 Pfam PF00174 Oxidoreductase molybdopterin binding domain 109 269 8.3E-31 T 13-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 MADE_1013425 e7f1f3bf1760f1aa7fdfc9e59669bb28 335 SUPERFAMILY SSF56524 79 323 3.01E-90 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MADE_1013425 e7f1f3bf1760f1aa7fdfc9e59669bb28 335 Gene3D G3DSA:3.90.420.10 66 335 7.1E-114 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 MADE_000001023535 81af486646a1b73ad1fe8be0da8886c0 293 Gene3D G3DSA:3.30.479.30 54 190 1.5E-23 T 13-10-2018 MADE_000001023535 81af486646a1b73ad1fe8be0da8886c0 293 TIGRFAM TIGR01932 hflC: HflC protein 148 288 7.3E-55 T 13-10-2018 IPR010200 HflC GO:0016021|GO:0052547 MADE_000001023535 81af486646a1b73ad1fe8be0da8886c0 293 TIGRFAM TIGR01932 hflC: HflC protein 1 154 1.5E-54 T 13-10-2018 IPR010200 HflC GO:0016021|GO:0052547 MADE_000001023535 81af486646a1b73ad1fe8be0da8886c0 293 Pfam PF01145 SPFH domain / Band 7 family 23 204 3.8E-34 T 13-10-2018 IPR001107 Band 7 domain MADE_000001023535 81af486646a1b73ad1fe8be0da8886c0 293 SUPERFAMILY SSF117892 57 193 8.11E-31 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily MADE_000001023535 81af486646a1b73ad1fe8be0da8886c0 293 PIRSF PIRSF005651 1 293 1.6E-99 T 13-10-2018 IPR010200 HflC GO:0016021|GO:0052547 MADE_000001023535 81af486646a1b73ad1fe8be0da8886c0 293 SMART SM00244 18 188 1.4E-41 T 13-10-2018 IPR001107 Band 7 domain MADE_000001022985 9e81b9d7e4d54d58858c27d345213a29 468 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 24 468 8.4E-187 T 13-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MADE_000001022985 9e81b9d7e4d54d58858c27d345213a29 468 Pfam PF11973 NQRA C-terminal domain 283 331 3.7E-19 T 13-10-2018 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 MADE_000001022985 9e81b9d7e4d54d58858c27d345213a29 468 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 23 278 1.5E-109 T 13-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MADE_000001022985 9e81b9d7e4d54d58858c27d345213a29 468 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 23 468 45.123 T 13-10-2018 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 Pfam PF01018 GTP1/OBG 4 157 6.0E-57 T 13-10-2018 IPR006169 GTP1/OBG domain MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 9.1E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 9.1E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 9.1E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 9.1E-35 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 6.6E-147 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 Hamap MF_01454 GTPase Obg [obg]. 2 333 47.46 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 Gene3D G3DSA:2.70.210.12 1 158 9.4E-59 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 SUPERFAMILY SSF82051 2 157 1.7E-54 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 Gene3D G3DSA:3.40.50.300 159 336 4.5E-52 T 13-10-2018 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 SUPERFAMILY SSF52540 152 343 1.23E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 PIRSF PIRSF002401 1 373 1.6E-139 T 13-10-2018 IPR035101 GTP-binding protein, Obg-type MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 Pfam PF01926 50S ribosome-binding GTPase 161 284 8.7E-25 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 MADE_1003345 0e7db836384ad5ce5c2f3ae06f8d4326 392 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 13-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 Gene3D G3DSA:3.40.50.300 1 139 8.4E-47 T 13-10-2018 MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 SUPERFAMILY SSF52540 1 209 6.02E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 Gene3D G3DSA:1.20.272.10 213 337 2.1E-29 T 13-10-2018 MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 Pfam PF06144 DNA polymerase III, delta subunit 20 189 5.3E-28 T 13-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 214 330 2.0E-13 T 13-10-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 326 4.9E-77 T 13-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 Gene3D G3DSA:1.10.8.60 142 211 5.1E-23 T 13-10-2018 MADE_000001021835 41bf9636e13d28ecb9d503c7ad74f0d7 341 SUPERFAMILY SSF48019 211 330 2.95E-25 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 MADE_1010410 e415b83edb4b9e92085af91c6c4c4202 477 Gene3D G3DSA:1.20.210.10 4 474 5.9E-205 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1010410 e415b83edb4b9e92085af91c6c4c4202 477 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 10 465 1.6E-228 T 13-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 MADE_1010410 e415b83edb4b9e92085af91c6c4c4202 477 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 14 444 1.3E-114 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1010410 e415b83edb4b9e92085af91c6c4c4202 477 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 205 260 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1010410 e415b83edb4b9e92085af91c6c4c4202 477 SUPERFAMILY SSF81442 11 466 1.44E-122 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 Gene3D G3DSA:3.90.1170.10 1 136 7.0E-54 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 PRINTS PR00060 Ribosomal protein L16 signature 87 116 2.7E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 PRINTS PR00060 Ribosomal protein L16 signature 41 52 2.7E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 PRINTS PR00060 Ribosomal protein L16 signature 23 35 2.7E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 PRINTS PR00060 Ribosomal protein L16 signature 57 86 2.7E-39 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 58 69 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 SUPERFAMILY SSF54686 3 133 1.44E-53 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 133 37.639 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 125 2.3E-56 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1002295 17f71db586cf84e0a000d72f064b6a3b 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 5.2E-45 T 13-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 MADE_1016845 bcbb2f761a072bf7308b8cea357caf82 364 Pfam PF01420 Type I restriction modification DNA specificity domain 166 331 1.6E-6 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MADE_1016845 bcbb2f761a072bf7308b8cea357caf82 364 Pfam PF01420 Type I restriction modification DNA specificity domain 6 140 2.4E-15 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 MADE_1016845 bcbb2f761a072bf7308b8cea357caf82 364 SUPERFAMILY SSF116734 8 155 2.45E-26 T 13-10-2018 MADE_1016845 bcbb2f761a072bf7308b8cea357caf82 364 SUPERFAMILY SSF116734 167 363 9.97E-34 T 13-10-2018 MADE_1016845 bcbb2f761a072bf7308b8cea357caf82 364 Gene3D G3DSA:3.90.220.20 165 358 3.1E-33 T 13-10-2018 MADE_1016845 bcbb2f761a072bf7308b8cea357caf82 364 Gene3D G3DSA:3.90.220.20 2 156 3.2E-25 T 13-10-2018 MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 Gene3D G3DSA:3.40.50.300 1 284 1.7E-131 T 13-10-2018 MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 Hamap MF_01227 CTP synthase [pyrG]. 2 539 51.144 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 SUPERFAMILY SSF52317 288 541 2.81E-87 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 TIGRFAM TIGR00337 PyrG: CTP synthase 2 534 8.3E-257 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 Pfam PF00117 Glutamine amidotransferase class-I 300 533 2.7E-60 T 13-10-2018 IPR017926 Glutamine amidotransferase MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 Pfam PF06418 CTP synthase N-terminus 4 265 2.3E-123 T 13-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 Gene3D G3DSA:3.40.50.880 285 543 1.9E-104 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1004720 8074154f892b6818f98b97ba5a3a3bb1 543 SUPERFAMILY SSF52540 1 268 8.99E-120 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 SUPERFAMILY SSF55874 310 462 8.38E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 SUPERFAMILY SSF47384 204 243 5.49E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 462 2.6E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 Gene3D G3DSA:3.30.450.40 14 201 3.7E-5 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 SMART SM00387 354 464 1.6E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 Gene3D G3DSA:3.30.565.10 315 472 1.8E-43 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 2.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 461 2.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 2.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 2.4E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1008340 188b4ff65c34189f934f9ec1b766d476 482 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 302 1.3E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1012245 021b1caa40ebc8ed1796d0ca31d6c76d 200 SUPERFAMILY SSF48317 41 188 1.05E-21 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MADE_1012245 021b1caa40ebc8ed1796d0ca31d6c76d 200 Pfam PF01569 PAP2 superfamily 75 184 7.8E-14 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MADE_1012245 021b1caa40ebc8ed1796d0ca31d6c76d 200 SMART SM00014 71 183 1.4E-8 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MADE_1012245 021b1caa40ebc8ed1796d0ca31d6c76d 200 Gene3D G3DSA:1.20.144.10 103 200 1.1E-13 T 13-10-2018 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 14 282 2.4E-121 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 621 6.2E-286 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 625 45.177 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 SMART SM00861 319 483 2.0E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 Pfam PF02780 Transketolase, C-terminal domain 507 616 9.4E-23 T 13-10-2018 IPR033248 Transketolase, C-terminal domain MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 Gene3D G3DSA:3.40.50.970 317 490 3.2E-65 T 13-10-2018 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 SUPERFAMILY SSF52518 316 502 7.74E-56 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 SUPERFAMILY SSF52922 492 624 7.59E-28 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 ProSitePatterns PS00801 Transketolase signature 1. 36 55 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 Pfam PF02779 Transketolase, pyrimidine binding domain 319 478 9.2E-38 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 Gene3D G3DSA:3.40.50.920 495 625 2.7E-36 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 MADE_1012415 08ac0734d7363212bbf7db8aa374563f 625 SUPERFAMILY SSF52518 7 381 2.79E-80 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold MADE_1005690 7d09a86d0209787e9ff4e5ae8445bc02 238 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 104 236 9.2E-36 T 13-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal MADE_1005690 7d09a86d0209787e9ff4e5ae8445bc02 238 Gene3D G3DSA:2.30.30.760 180 238 1.2E-10 T 13-10-2018 MADE_1005690 7d09a86d0209787e9ff4e5ae8445bc02 238 SMART SM00858 116 178 3.0E-8 T 13-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 MADE_1005690 7d09a86d0209787e9ff4e5ae8445bc02 238 Pfam PF13144 Chaperone for flagella basal body P-ring formation 41 235 7.0E-44 T 13-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal MADE_1005690 7d09a86d0209787e9ff4e5ae8445bc02 238 Gene3D G3DSA:3.90.1210.10 114 179 3.8E-6 T 13-10-2018 MADE_000001023040 a0c2e660c93a84810cd4b291ed8ba27f 297 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 97 228 4.8E-7 T 13-10-2018 MADE_000001023040 a0c2e660c93a84810cd4b291ed8ba27f 297 Gene3D G3DSA:3.40.190.10 151 230 3.8E-8 T 13-10-2018 MADE_000001023040 a0c2e660c93a84810cd4b291ed8ba27f 297 Gene3D G3DSA:3.40.190.10 101 150 3.8E-8 T 13-10-2018 MADE_000001023040 a0c2e660c93a84810cd4b291ed8ba27f 297 SUPERFAMILY SSF53850 100 238 7.35E-9 T 13-10-2018 MADE_000001023070 e558eeba4e60d8cd3d7f79259d06d4f1 139 Gene3D G3DSA:1.20.120.550 1 139 9.8E-19 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MADE_000001023070 e558eeba4e60d8cd3d7f79259d06d4f1 139 SUPERFAMILY SSF161084 6 131 1.44E-20 T 13-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily MADE_000001023070 e558eeba4e60d8cd3d7f79259d06d4f1 139 Pfam PF01124 MAPEG family 10 135 2.8E-18 T 13-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein MADE_000001023635 6c3659819375352f27de4cbc1e8f4e9b 420 TIGRFAM TIGR01272 gluP: glucose/galactose transporter WARNING 105 405 1.7E-111 T 13-10-2018 IPR005964 Bacterial glucose/galactose transporter GO:0005354|GO:0005355|GO:0015757|GO:0016021|GO:1904659 MADE_000001023635 6c3659819375352f27de4cbc1e8f4e9b 420 SUPERFAMILY SSF103473 14 409 2.49E-38 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_000001023635 6c3659819375352f27de4cbc1e8f4e9b 420 Gene3D G3DSA:1.20.1250.20 229 414 7.6E-59 T 13-10-2018 MADE_000001023635 6c3659819375352f27de4cbc1e8f4e9b 420 Gene3D G3DSA:1.20.1250.20 19 224 1.4E-55 T 13-10-2018 MADE_000001023635 6c3659819375352f27de4cbc1e8f4e9b 420 Pfam PF07690 Major Facilitator Superfamily 31 356 7.2E-17 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 26 911 6.2E-220 T 13-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 Pfam PF00271 Helicase conserved C-terminal domain 231 353 1.7E-12 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 Gene3D G3DSA:1.20.120.1080 396 517 1.0E-6 T 13-10-2018 MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 Gene3D G3DSA:3.40.50.300 205 373 3.3E-51 T 13-10-2018 MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 Gene3D G3DSA:3.40.50.300 17 203 5.0E-48 T 13-10-2018 MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 Pfam PF00270 DEAD/DEAH box helicase 41 182 2.2E-7 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 Pfam PF08482 ATP-dependent helicase C-terminal 769 899 1.8E-43 T 13-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 SMART SM00490 255 354 3.9E-12 T 13-10-2018 IPR001650 Helicase, C-terminal MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 SUPERFAMILY SSF52540 42 365 2.58E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 SMART SM00487 13 211 8.6E-19 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain MADE_1002380 c4e552f40dc4e9a7ed5066cfe5c652b9 912 Pfam PF04408 Helicase associated domain (HA2) 414 491 5.7E-6 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 MADE_1014990 66aab09dd4af28da81d452f0e9a515fd 289 Pfam PF17113 Regulatory signalling modulator protein AmpE 1 288 7.0E-32 T 13-10-2018 IPR031347 Protein AmpE MADE_1008705 c684533b0850c5d4bed2773a4ea14df0 79 Gene3D G3DSA:1.10.1200.10 1 75 4.3E-30 T 13-10-2018 IPR036736 ACP-like superfamily MADE_1008705 c684533b0850c5d4bed2773a4ea14df0 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.1E-16 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain MADE_1008705 c684533b0850c5d4bed2773a4ea14df0 79 SUPERFAMILY SSF47336 2 76 7.46E-24 T 13-10-2018 IPR036736 ACP-like superfamily MADE_1008705 c684533b0850c5d4bed2773a4ea14df0 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 13-10-2018 IPR006162 Phosphopantetheine attachment site MADE_1008705 c684533b0850c5d4bed2773a4ea14df0 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.101 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MADE_1008705 c684533b0850c5d4bed2773a4ea14df0 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 3.4E-37 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 MADE_1005685 c67b6c099ea23972f2dd709c4b3621f9 109 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 101 2.0E-19 T 13-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 MADE_1005685 c67b6c099ea23972f2dd709c4b3621f9 109 SUPERFAMILY SSF101498 23 101 6.15E-15 T 13-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily MADE_1005685 c67b6c099ea23972f2dd709c4b3621f9 109 Pfam PF04316 Anti-sigma-28 factor, FlgM 47 99 1.9E-15 T 13-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal MADE_1001425 6135f6f94c7281a57e09d8f06762c987 97 SUPERFAMILY SSF55658 16 58 2.82E-12 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal MADE_1001425 6135f6f94c7281a57e09d8f06762c987 97 Pfam PF01693 Caulimovirus viroplasmin 16 57 2.4E-15 T 13-10-2018 IPR011320 Ribonuclease H1, N-terminal MADE_1001425 6135f6f94c7281a57e09d8f06762c987 97 Gene3D G3DSA:3.40.970.10 15 58 1.5E-14 T 13-10-2018 IPR037056 Ribonuclease H1, N-terminal domain superfamily MADE_1007290 cd81974d1f6095e23b734de772a4215e 311 SUPERFAMILY SSF52540 78 284 5.92E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1007290 cd81974d1f6095e23b734de772a4215e 311 Gene3D G3DSA:3.40.50.300 59 307 2.6E-50 T 13-10-2018 MADE_1007290 cd81974d1f6095e23b734de772a4215e 311 SMART SM00382 82 268 1.0E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1007290 cd81974d1f6095e23b734de772a4215e 311 ProSitePatterns PS00211 ABC transporters family signature. 185 199 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1007290 cd81974d1f6095e23b734de772a4215e 311 Pfam PF00005 ABC transporter 78 219 2.2E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1018355 e46148ce9102e693749b8271ec9b45ea 304 Gene3D G3DSA:3.40.630.30 3 145 1.1E-23 T 13-10-2018 MADE_1018355 e46148ce9102e693749b8271ec9b45ea 304 SUPERFAMILY SSF54637 153 297 1.01E-42 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1018355 e46148ce9102e693749b8271ec9b45ea 304 Gene3D G3DSA:3.10.129.10 146 298 7.1E-49 T 13-10-2018 MADE_1018355 e46148ce9102e693749b8271ec9b45ea 304 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 157 296 1.1E-52 T 13-10-2018 IPR012660 Thioesterase, putative MADE_1018355 e46148ce9102e693749b8271ec9b45ea 304 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 164 296 6.9E-43 T 13-10-2018 IPR012660 Thioesterase, putative MADE_1018355 e46148ce9102e693749b8271ec9b45ea 304 Pfam PF00583 Acetyltransferase (GNAT) family 20 122 2.7E-12 T 13-10-2018 IPR000182 GNAT domain MADE_1018355 e46148ce9102e693749b8271ec9b45ea 304 SUPERFAMILY SSF55729 2 166 5.91E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1000375 ca5344339b6cc4ce979e002cf2cfa74a 135 SUPERFAMILY SSF46626 55 132 4.3E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1000375 ca5344339b6cc4ce979e002cf2cfa74a 135 PRINTS PR00607 Class IE cytochrome C signature 106 118 4.6E-16 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MADE_1000375 ca5344339b6cc4ce979e002cf2cfa74a 135 PRINTS PR00607 Class IE cytochrome C signature 77 87 4.6E-16 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MADE_1000375 ca5344339b6cc4ce979e002cf2cfa74a 135 PRINTS PR00607 Class IE cytochrome C signature 121 132 4.6E-16 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MADE_1000375 ca5344339b6cc4ce979e002cf2cfa74a 135 PRINTS PR00607 Class IE cytochrome C signature 66 77 4.6E-16 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 MADE_1000375 ca5344339b6cc4ce979e002cf2cfa74a 135 Gene3D G3DSA:1.10.760.10 53 133 1.5E-32 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1000375 ca5344339b6cc4ce979e002cf2cfa74a 135 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 56 131 5.5E-17 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1004775 f452121e77e403d6d6b8ec322d4a9c68 73 Pfam PF04995 Heme exporter protein D (CcmD) 13 54 4.5E-11 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 MADE_1004775 f452121e77e403d6d6b8ec322d4a9c68 73 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 10 54 1.6E-16 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 MADE_1003945 e149cf4dc30380b19c8e26f5efd169fb 317 Pfam PF01068 ATP dependent DNA ligase domain 32 231 1.6E-8 T 13-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 MADE_1003945 e149cf4dc30380b19c8e26f5efd169fb 317 Gene3D G3DSA:3.30.470.30 57 120 4.4E-19 T 13-10-2018 MADE_1003945 e149cf4dc30380b19c8e26f5efd169fb 317 Pfam PF14743 DNA ligase OB-like domain 246 310 3.1E-28 T 13-10-2018 IPR029319 DNA ligase, OB-like domain MADE_1003945 e149cf4dc30380b19c8e26f5efd169fb 317 Gene3D G3DSA:2.40.50.140 243 315 2.1E-9 T 13-10-2018 MADE_1003945 e149cf4dc30380b19c8e26f5efd169fb 317 SUPERFAMILY SSF50249 206 310 8.0E-28 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1003945 e149cf4dc30380b19c8e26f5efd169fb 317 SUPERFAMILY SSF56091 31 231 1.04E-34 T 13-10-2018 MADE_1003945 e149cf4dc30380b19c8e26f5efd169fb 317 Gene3D G3DSA:3.30.1490.70 179 232 3.5E-16 T 13-10-2018 MADE_1013435 374ca02f033fb20735907a67b8ae0aeb 132 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 1 106 8.0E-5 T 13-10-2018 IPR020143 Uncharacterised protein family, RP436 MADE_1013435 374ca02f033fb20735907a67b8ae0aeb 132 Pfam PF09335 SNARE associated Golgi protein 18 130 2.7E-13 T 13-10-2018 IPR032816 SNARE associated Golgi protein MADE_1000955 e83fd6f9ccd3e7fb24f29607f82d596c 105 Pfam PF12305 Protein of unknown function (DUF3630) 33 92 5.0E-6 T 13-10-2018 IPR022080 Protein of unknown function DUF3630 MADE_1005340 9a6c5c2d4a6b6e6359467758e81e2a42 261 Gene3D G3DSA:3.40.1180.10 7 251 3.3E-95 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MADE_1005340 9a6c5c2d4a6b6e6359467758e81e2a42 261 Pfam PF01255 Putative undecaprenyl diphosphate synthase 30 250 3.6E-83 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MADE_1005340 9a6c5c2d4a6b6e6359467758e81e2a42 261 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 23 251 40.607 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MADE_1005340 9a6c5c2d4a6b6e6359467758e81e2a42 261 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 250 1.3E-100 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 MADE_1005340 9a6c5c2d4a6b6e6359467758e81e2a42 261 SUPERFAMILY SSF64005 23 246 8.5E-89 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 MADE_1005340 9a6c5c2d4a6b6e6359467758e81e2a42 261 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 196 213 - T 13-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 MADE_1006740 afcbb5e94b613e56ffc388204f5852fa 304 PIRSF PIRSF002936 2 304 8.2E-153 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MADE_1006740 afcbb5e94b613e56ffc388204f5852fa 304 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 6 304 56.593 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MADE_1006740 afcbb5e94b613e56ffc388204f5852fa 304 SUPERFAMILY SSF52402 8 211 7.85E-70 T 13-10-2018 MADE_1006740 afcbb5e94b613e56ffc388204f5852fa 304 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 259 9.7E-60 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MADE_1006740 afcbb5e94b613e56ffc388204f5852fa 304 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 11 304 1.1E-155 T 13-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 MADE_1006740 afcbb5e94b613e56ffc388204f5852fa 304 Gene3D G3DSA:3.40.50.620 9 213 8.3E-63 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1004180 ae4f07aea33bf118e189ce1d11ecf77c 95 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 1.3E-28 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MADE_1004180 ae4f07aea33bf118e189ce1d11ecf77c 95 SUPERFAMILY SSF69754 1 95 3.4E-36 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like MADE_1004180 ae4f07aea33bf118e189ce1d11ecf77c 95 Gene3D G3DSA:3.30.160.100 1 95 1.1E-37 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like MADE_1004180 ae4f07aea33bf118e189ce1d11ecf77c 95 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 4.4E-34 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 Pfam PF08442 ATP-grasp domain 2 203 7.1E-81 T 13-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.364 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 PIRSF PIRSF001554 1 388 6.2E-153 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 13-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.5E-174 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 Gene3D G3DSA:3.40.50.261 240 388 2.1E-57 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 SUPERFAMILY SSF56059 1 238 1.66E-80 T 13-10-2018 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 Gene3D G3DSA:3.30.470.20 1 234 8.0E-93 T 13-10-2018 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 SUPERFAMILY SSF52210 240 385 1.96E-54 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 Pfam PF00549 CoA-ligase 262 382 4.7E-25 T 13-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 MADE_1009505 2bf9a50fd0b4e4bc753b9cd6f8f7b409 388 Gene3D G3DSA:3.30.1490.20 21 104 8.0E-93 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1007875 97b6dd835ae5749d709f2aeca35498d3 644 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 12 301 3.2E-74 T 13-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 MADE_1007875 97b6dd835ae5749d709f2aeca35498d3 644 SUPERFAMILY SSF51735 417 561 1.84E-30 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1007875 97b6dd835ae5749d709f2aeca35498d3 644 Gene3D G3DSA:1.20.1530.20 2 398 2.0E-77 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily MADE_1007875 97b6dd835ae5749d709f2aeca35498d3 644 Pfam PF02254 TrkA-N domain 421 534 2.7E-21 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MADE_1007875 97b6dd835ae5749d709f2aeca35498d3 644 Pfam PF00999 Sodium/hydrogen exchanger family 10 388 8.6E-59 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MADE_1007875 97b6dd835ae5749d709f2aeca35498d3 644 Gene3D G3DSA:3.40.50.720 420 576 2.3E-33 T 13-10-2018 MADE_1013565 669c7521a344a243dfd962021d0f9a51 815 Pfam PF17148 Domain of unknown function (DUF5117) 98 290 4.9E-37 T 13-10-2018 IPR033413 Domain of unknown function DUF5117 MADE_1013565 669c7521a344a243dfd962021d0f9a51 815 Pfam PF16313 Met-zincin 416 729 1.4E-61 T 13-10-2018 IPR032534 Domain of unknown function DUF4953 MADE_1013565 669c7521a344a243dfd962021d0f9a51 815 SUPERFAMILY SSF55486 290 494 1.8E-24 T 13-10-2018 MADE_1013565 669c7521a344a243dfd962021d0f9a51 815 Gene3D G3DSA:3.40.390.10 359 492 5.2E-7 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 MADE_1005405 547717597c206fd5e9f48e77bf893092 299 SMART SM00267 131 299 9.4E-52 T 13-10-2018 IPR000160 GGDEF domain MADE_1005405 547717597c206fd5e9f48e77bf893092 299 Gene3D G3DSA:3.30.70.270 136 299 4.0E-49 T 13-10-2018 MADE_1005405 547717597c206fd5e9f48e77bf893092 299 Pfam PF00990 Diguanylate cyclase, GGDEF domain 143 294 2.8E-41 T 13-10-2018 IPR000160 GGDEF domain MADE_1005405 547717597c206fd5e9f48e77bf893092 299 SUPERFAMILY SSF55073 147 297 7.3E-44 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1005405 547717597c206fd5e9f48e77bf893092 299 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 139 297 1.0E-42 T 13-10-2018 IPR000160 GGDEF domain MADE_1013875 fdda1dbc3dccabb6093645e510637f6c 378 Pfam PF04577 Protein of unknown function (DUF563) 81 266 4.6E-20 T 13-10-2018 IPR007657 Glycosyltransferase 61 GO:0016757 MADE_1018460 ee6fe8d72b37f203a32ea6b347829bfd 222 Gene3D G3DSA:3.40.50.150 21 218 1.5E-27 T 13-10-2018 MADE_1018460 ee6fe8d72b37f203a32ea6b347829bfd 222 Pfam PF02390 Putative methyltransferase 57 214 4.3E-11 T 13-10-2018 MADE_1018460 ee6fe8d72b37f203a32ea6b347829bfd 222 SUPERFAMILY SSF53335 32 116 1.96E-14 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1001500 0a93ece5f0b123cea62d110d460312f5 429 Pfam PF02321 Outer membrane efflux protein 42 218 1.9E-10 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1001500 0a93ece5f0b123cea62d110d460312f5 429 Pfam PF02321 Outer membrane efflux protein 242 419 1.6E-12 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1001500 0a93ece5f0b123cea62d110d460312f5 429 SUPERFAMILY SSF56954 15 420 5.1E-55 T 13-10-2018 MADE_1001500 0a93ece5f0b123cea62d110d460312f5 429 Gene3D G3DSA:1.20.1600.10 35 428 6.1E-43 T 13-10-2018 MADE_1012185 4940d8e3fce8692ebb121005916b6c79 164 PIRSF PIRSF006173 1 160 7.5E-52 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 MADE_1012185 4940d8e3fce8692ebb121005916b6c79 164 Pfam PF03692 Putative zinc- or iron-chelating domain 23 103 7.2E-8 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein MADE_1008100 b842a5fd7241c2a57a97349bd898d956 469 Pfam PF01050 Mannose-6-phosphate isomerase 311 461 4.5E-74 T 13-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MADE_1008100 b842a5fd7241c2a57a97349bd898d956 469 SUPERFAMILY SSF53448 1 276 6.34E-70 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008100 b842a5fd7241c2a57a97349bd898d956 469 Pfam PF00483 Nucleotidyl transferase 2 281 7.2E-71 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MADE_1008100 b842a5fd7241c2a57a97349bd898d956 469 Gene3D G3DSA:2.60.120.10 343 453 1.0E-20 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1008100 b842a5fd7241c2a57a97349bd898d956 469 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1 465 1.4E-227 T 13-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 MADE_1008100 b842a5fd7241c2a57a97349bd898d956 469 SUPERFAMILY SSF51182 181 465 1.2E-90 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1008100 b842a5fd7241c2a57a97349bd898d956 469 Gene3D G3DSA:3.90.550.10 1 342 8.0E-119 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1016040 381ddf40f45e7df3528ae4f62f166ba0 427 Pfam PF13416 Bacterial extracellular solute-binding protein 130 335 4.8E-11 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein MADE_1016040 381ddf40f45e7df3528ae4f62f166ba0 427 Gene3D G3DSA:3.40.190.10 173 335 4.3E-20 T 13-10-2018 MADE_1016040 381ddf40f45e7df3528ae4f62f166ba0 427 SUPERFAMILY SSF53850 40 425 2.9E-43 T 13-10-2018 MADE_1002330 760d910d7844c0ba1701a18b2eae8c69 359 Gene3D G3DSA:3.40.50.2000 7 167 4.9E-30 T 13-10-2018 MADE_1002330 760d910d7844c0ba1701a18b2eae8c69 359 Gene3D G3DSA:3.40.50.2000 183 358 2.7E-36 T 13-10-2018 MADE_1002330 760d910d7844c0ba1701a18b2eae8c69 359 SUPERFAMILY SSF53756 6 356 2.04E-72 T 13-10-2018 MADE_1002330 760d910d7844c0ba1701a18b2eae8c69 359 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 90 331 8.7E-42 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 MADE_000001023120 b4701fe5889dfaa2e14b54f66eb7ee6a 144 Gene3D G3DSA:2.40.70.10 3 133 8.9E-34 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_000001023120 b4701fe5889dfaa2e14b54f66eb7ee6a 144 SUPERFAMILY SSF50630 6 140 1.03E-41 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_000001023120 b4701fe5889dfaa2e14b54f66eb7ee6a 144 Pfam PF05618 Putative ATP-dependant zinc protease 6 138 1.4E-31 T 13-10-2018 MADE_1001415 0f6e2d3f0872b9edf215ebb8c7650a02 252 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 215 252 5.2E-13 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MADE_1001415 0f6e2d3f0872b9edf215ebb8c7650a02 252 Gene3D G3DSA:3.40.1350.10 96 230 1.8E-9 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 MADE_1001415 0f6e2d3f0872b9edf215ebb8c7650a02 252 Pfam PF04471 Restriction endonuclease 90 200 2.0E-29 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 MADE_1001415 0f6e2d3f0872b9edf215ebb8c7650a02 252 SUPERFAMILY SSF52980 95 204 6.97E-28 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 MADE_1001415 0f6e2d3f0872b9edf215ebb8c7650a02 252 SUPERFAMILY SSF57783 211 251 3.32E-8 T 13-10-2018 MADE_1004450 b72e923193717bb28448d6e38c809134 178 Gene3D G3DSA:3.40.30.10 1 162 3.3E-21 T 13-10-2018 MADE_1004450 b72e923193717bb28448d6e38c809134 178 SUPERFAMILY SSF52833 10 175 2.41E-28 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1004450 b72e923193717bb28448d6e38c809134 178 Pfam PF08534 Redoxin 10 143 1.1E-17 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MADE_1000195 9fc7804d8367217e9360deac84ebdd67 234 SUPERFAMILY SSF52540 66 157 2.43E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1000195 9fc7804d8367217e9360deac84ebdd67 234 Gene3D G3DSA:3.40.50.300 50 156 2.2E-26 T 13-10-2018 MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 Pfam PF00106 short chain dehydrogenase 8 202 1.4E-49 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 SUPERFAMILY SSF51735 2 251 2.96E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 Gene3D G3DSA:3.40.50.720 2 288 1.0E-71 T 13-10-2018 MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.3E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.3E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.3E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.3E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.3E-21 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1014145 2ac366ca0ae353287d5487bac6b1d360 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.2E-9 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1009265 0099e6d31983cbd70abcfff5ce6edc7e 126 Gene3D G3DSA:3.10.180.10 1 109 6.1E-16 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1009265 0099e6d31983cbd70abcfff5ce6edc7e 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 107 1.8E-5 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_1009265 0099e6d31983cbd70abcfff5ce6edc7e 126 SUPERFAMILY SSF54593 2 121 7.52E-22 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1012455 6455760737dd7f5256e6787379375e28 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 4.2E-70 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MADE_1012455 6455760737dd7f5256e6787379375e28 149 Pfam PF03477 ATP cone domain 50 136 1.5E-18 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 MADE_1012455 6455760737dd7f5256e6787379375e28 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 87.137 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 MADE_1019685 2aae6a8ca2b828c1355d035ea187887f 94 Pfam PF10985 Protein of unknown function (DUF2805) 16 86 1.0E-34 T 13-10-2018 IPR019882 Conserved hypothetical protein CHP03643 MADE_1019685 2aae6a8ca2b828c1355d035ea187887f 94 TIGRFAM TIGR03643 TIGR03643: TIGR03643 family protein 15 83 3.3E-34 T 13-10-2018 IPR019882 Conserved hypothetical protein CHP03643 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 Gene3D G3DSA:3.40.50.720 37 336 9.7E-79 T 13-10-2018 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 SUPERFAMILY SSF51735 22 186 3.18E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 178 273 1.1E-5 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 35 158 2.4E-24 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 32 45 1.4E-14 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 329 345 1.4E-14 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 148 162 1.4E-14 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 PRINTS PR01775 Bacterial glucose-fructose oxidoreductase signature 86 102 1.4E-14 T 13-10-2018 IPR008354 Glucose-fructose oxidoreductase, bacterial MetaCyc: PWY-5530 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 Gene3D G3DSA:3.30.360.10 163 358 9.7E-79 T 13-10-2018 MADE_1016150 7fbb972e488f12a634dc19d8ecb61168 362 SUPERFAMILY SSF55347 164 319 5.4E-23 T 13-10-2018 MADE_1018235 dc5a57ca90b9a86c5aab5b8602360c63 352 SUPERFAMILY SSF53300 149 344 2.04E-11 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1018235 dc5a57ca90b9a86c5aab5b8602360c63 352 Pfam PF13519 von Willebrand factor type A domain 152 272 6.2E-7 T 13-10-2018 IPR002035 von Willebrand factor, type A MADE_1018235 dc5a57ca90b9a86c5aab5b8602360c63 352 Gene3D G3DSA:3.40.50.410 152 348 9.0E-11 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1010935 7a81efbae534aa0cda6706fbdb1f91b9 584 PIRSF PIRSF003059 7 580 2.6E-173 T 13-10-2018 IPR016377 Sucrose/Glucosylglycerate phosphorylase-related MADE_1010935 7a81efbae534aa0cda6706fbdb1f91b9 584 SUPERFAMILY SSF51445 56 542 5.89E-94 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily MADE_1010935 7a81efbae534aa0cda6706fbdb1f91b9 584 Gene3D G3DSA:3.90.400.10 145 218 4.6E-155 T 13-10-2018 MADE_1010935 7a81efbae534aa0cda6706fbdb1f91b9 584 Gene3D G3DSA:3.20.20.80 63 468 4.6E-155 T 13-10-2018 MADE_1010935 7a81efbae534aa0cda6706fbdb1f91b9 584 Gene3D G3DSA:2.60.40.1180 506 579 8.1E-9 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta MADE_1010935 7a81efbae534aa0cda6706fbdb1f91b9 584 Pfam PF00128 Alpha amylase, catalytic domain 94 348 4.8E-18 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1010935 7a81efbae534aa0cda6706fbdb1f91b9 584 SMART SM00642 60 491 7.5E-7 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 MADE_1015235 a607d78eb8a97e2c2d43f3c22a7dce9e 147 SUPERFAMILY SSF56954 30 135 4.19E-12 T 13-10-2018 MADE_1015235 a607d78eb8a97e2c2d43f3c22a7dce9e 147 Pfam PF02321 Outer membrane efflux protein 53 138 5.2E-5 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1015235 a607d78eb8a97e2c2d43f3c22a7dce9e 147 Gene3D G3DSA:1.20.1600.10 47 143 3.1E-6 T 13-10-2018 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 Pfam PF00186 Dihydrofolate reductase 2 165 1.2E-59 T 13-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 PIRSF PIRSF000194 1 167 1.7E-62 T 13-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 Gene3D G3DSA:3.40.430.10 1 167 7.5E-59 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 PRINTS PR00070 Dihydrofolate reductase signature 41 52 3.2E-15 T 13-10-2018 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 PRINTS PR00070 Dihydrofolate reductase signature 14 24 3.2E-15 T 13-10-2018 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 PRINTS PR00070 Dihydrofolate reductase signature 28 36 3.2E-15 T 13-10-2018 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 PRINTS PR00070 Dihydrofolate reductase signature 96 110 3.2E-15 T 13-10-2018 MADE_1003350 1d2b8d19648785cb1bfa99fc42854721 167 SUPERFAMILY SSF53597 1 165 1.7E-57 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 MADE_000001022030 d97132befe35fcba90576a236d2e387c 172 Gene3D G3DSA:3.10.129.10 2 172 7.5E-68 T 13-10-2018 MADE_000001022030 d97132befe35fcba90576a236d2e387c 172 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 172 53.009 T 13-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_000001022030 d97132befe35fcba90576a236d2e387c 172 SUPERFAMILY SSF54637 4 169 4.07E-59 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_000001022030 d97132befe35fcba90576a236d2e387c 172 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 172 6.3E-95 T 13-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_000001022030 d97132befe35fcba90576a236d2e387c 172 Pfam PF07977 FabA-like domain 29 158 2.9E-53 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_1003760 d4c17e6bc113a5f4b95230ba3bc8b9e9 235 Gene3D G3DSA:1.10.510.10 8 65 8.7E-8 T 13-10-2018 MADE_1003760 d4c17e6bc113a5f4b95230ba3bc8b9e9 235 Pfam PF01636 Phosphotransferase enzyme family 10 165 2.7E-26 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase MADE_1003760 d4c17e6bc113a5f4b95230ba3bc8b9e9 235 SUPERFAMILY SSF56112 10 231 2.49E-61 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1003760 d4c17e6bc113a5f4b95230ba3bc8b9e9 235 Gene3D G3DSA:1.20.1270.170 130 227 8.6E-39 T 13-10-2018 MADE_1019850 10a99f98b44d77aa1cc12ec680a74392 159 TIGRFAM TIGR01707 gspI: type II secretion system protein I 40 137 6.0E-26 T 13-10-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 MADE_1019850 10a99f98b44d77aa1cc12ec680a74392 159 Pfam PF02501 Type II secretion system (T2SS), protein I 75 152 2.0E-27 T 13-10-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 MADE_1019850 10a99f98b44d77aa1cc12ec680a74392 159 Pfam PF07963 Prokaryotic N-terminal methylation motif 36 60 2.0E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019850 10a99f98b44d77aa1cc12ec680a74392 159 Gene3D G3DSA:3.30.1300.30 67 153 9.5E-27 T 13-10-2018 MADE_1019850 10a99f98b44d77aa1cc12ec680a74392 159 SUPERFAMILY SSF54523 72 153 6.67E-25 T 13-10-2018 MADE_1019850 10a99f98b44d77aa1cc12ec680a74392 159 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 38 60 4.3E-4 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1019850 10a99f98b44d77aa1cc12ec680a74392 159 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 39 59 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_000001022460 f8e3cff6cdf07d19d35d2e7cec886d05 451 SUPERFAMILY SSF55920 195 404 5.63E-13 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like MADE_000001022460 f8e3cff6cdf07d19d35d2e7cec886d05 451 Gene3D G3DSA:3.90.230.10 193 439 4.8E-13 T 13-10-2018 MADE_000001022460 f8e3cff6cdf07d19d35d2e7cec886d05 451 Pfam PF00557 Metallopeptidase family M24 220 376 2.3E-9 T 13-10-2018 IPR000994 Peptidase M24 MADE_000001022630 6ecab462759735853b56343471f693e2 523 Pfam PF00474 Sodium:solute symporter family 32 426 1.0E-39 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_000001022630 6ecab462759735853b56343471f693e2 523 Gene3D G3DSA:1.20.1730.10 21 522 4.8E-103 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_000001022630 6ecab462759735853b56343471f693e2 523 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 32 440 3.4E-64 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_1015345 f88029d99a47cca1ca7d25a9ad40a399 347 Gene3D G3DSA:3.40.50.300 101 347 4.7E-106 T 13-10-2018 MADE_1015345 f88029d99a47cca1ca7d25a9ad40a399 347 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 341 1.4E-154 T 13-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 MADE_1015345 f88029d99a47cca1ca7d25a9ad40a399 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1015345 f88029d99a47cca1ca7d25a9ad40a399 347 Gene3D G3DSA:3.30.450.90 1 100 3.0E-35 T 13-10-2018 MADE_1015345 f88029d99a47cca1ca7d25a9ad40a399 347 SUPERFAMILY SSF52540 5 334 1.0E-72 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015345 f88029d99a47cca1ca7d25a9ad40a399 347 Pfam PF00437 Type II/IV secretion system protein 12 269 4.3E-51 T 13-10-2018 IPR001482 Type II/IV secretion system protein MADE_1014845 def864f44cf6ab84e33ae810413693cd 334 SUPERFAMILY SSF52540 5 163 8.4E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1014845 def864f44cf6ab84e33ae810413693cd 334 Gene3D G3DSA:3.40.50.300 5 167 9.2E-14 T 13-10-2018 MADE_1011495 b5daf09b03f1ae6ba69e7a7dc66957d7 469 Pfam PF03050 Transposase IS66 family 154 420 7.0E-49 T 13-10-2018 IPR004291 Transposase, IS66 MADE_1011495 b5daf09b03f1ae6ba69e7a7dc66957d7 469 Pfam PF13005 zinc-finger binding domain of transposase IS66 96 139 5.0E-6 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 MADE_1016790 b5daf09b03f1ae6ba69e7a7dc66957d7 469 Pfam PF03050 Transposase IS66 family 154 420 7.0E-49 T 13-10-2018 IPR004291 Transposase, IS66 MADE_1016790 b5daf09b03f1ae6ba69e7a7dc66957d7 469 Pfam PF13005 zinc-finger binding domain of transposase IS66 96 139 5.0E-6 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 MADE_1018980 e01cdd692876e337235021edcd974c32 501 Gene3D G3DSA:3.30.565.10 354 501 2.3E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018980 e01cdd692876e337235021edcd974c32 501 SUPERFAMILY SSF47384 248 295 7.46E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1018980 e01cdd692876e337235021edcd974c32 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 499 1.4E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018980 e01cdd692876e337235021edcd974c32 501 SMART SM00387 394 501 7.2E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1018980 e01cdd692876e337235021edcd974c32 501 SUPERFAMILY SSF55874 352 500 1.7E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1018980 e01cdd692876e337235021edcd974c32 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 351 2.7E-7 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 MADE_1018980 e01cdd692876e337235021edcd974c32 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 445 5.0E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018980 e01cdd692876e337235021edcd974c32 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 459 5.0E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018980 e01cdd692876e337235021edcd974c32 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 480 5.0E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1018980 e01cdd692876e337235021edcd974c32 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 499 5.0E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1009745 c6fc28f668d29f30e526f85119472311 152 Pfam PF01609 Transposase DDE domain 19 141 2.0E-6 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1010900 3d30d453bcbc0f46cc892ff862d3bab8 233 Gene3D G3DSA:3.40.33.10 41 181 1.4E-16 T 13-10-2018 IPR035940 CAP superfamily MADE_1011680 ad0b803ba3b1520724b8e0b70f0dd5c2 283 PIRSF PIRSF016020 1 283 1.3E-46 T 13-10-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 MADE_1011680 ad0b803ba3b1520724b8e0b70f0dd5c2 283 Pfam PF01263 Aldose 1-epimerase 22 278 4.6E-31 T 13-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 MADE_1011680 ad0b803ba3b1520724b8e0b70f0dd5c2 283 SUPERFAMILY SSF74650 7 280 2.39E-57 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 MADE_1011680 ad0b803ba3b1520724b8e0b70f0dd5c2 283 Gene3D G3DSA:2.70.98.10 3 282 2.3E-69 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 MADE_1006075 4ab7c26cd3b82bee4813475f3b74b1f9 808 Gene3D G3DSA:2.170.130.10 49 172 1.3E-12 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1006075 4ab7c26cd3b82bee4813475f3b74b1f9 808 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 791 808 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site MADE_1006075 4ab7c26cd3b82bee4813475f3b74b1f9 808 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 151 6.1E-9 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1006075 4ab7c26cd3b82bee4813475f3b74b1f9 808 SUPERFAMILY SSF56935 34 808 5.19E-74 T 13-10-2018 MADE_1006075 4ab7c26cd3b82bee4813475f3b74b1f9 808 Pfam PF00593 TonB dependent receptor 409 806 9.5E-31 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 PIRSF PIRSF001217 8 620 4.8E-205 T 13-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 Gene3D G3DSA:3.90.226.10 96 316 1.5E-157 T 13-10-2018 MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 Gene3D G3DSA:3.40.1750.10 187 502 1.5E-157 T 13-10-2018 MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 Pfam PF01343 Peptidase family S49 396 546 5.2E-49 T 13-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 Pfam PF01343 Peptidase family S49 139 289 1.7E-25 T 13-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 SUPERFAMILY SSF52096 320 534 1.96E-42 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 333 544 5.9E-52 T 13-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 Gene3D G3DSA:3.90.226.10 319 544 1.5E-157 T 13-10-2018 MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 SUPERFAMILY SSF52096 28 286 2.58E-24 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_000001021755 2d97cf3cfd31bd04ed2a6eea684276ec 621 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 613 6.9E-181 T 13-10-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 MADE_1001315 96b3b828018553d3484c64c1ac554048 488 Gene3D G3DSA:3.40.1260.20 402 487 1.7E-6 T 13-10-2018 MADE_1001315 96b3b828018553d3484c64c1ac554048 488 SUPERFAMILY SSF50249 39 127 8.0E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1001315 96b3b828018553d3484c64c1ac554048 488 Pfam PF00575 S1 RNA binding domain 38 109 9.3E-5 T 13-10-2018 IPR003029 S1 domain GO:0003676 MADE_1001315 96b3b828018553d3484c64c1ac554048 488 Pfam PF10150 Ribonuclease E/G family 124 392 2.7E-100 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 MADE_1001315 96b3b828018553d3484c64c1ac554048 488 SMART SM00316 37 122 1.5E-7 T 13-10-2018 IPR022967 RNA-binding domain, S1 MADE_1001315 96b3b828018553d3484c64c1ac554048 488 Gene3D G3DSA:2.40.50.140 30 127 8.7E-31 T 13-10-2018 MADE_1001315 96b3b828018553d3484c64c1ac554048 488 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 425 1.7E-162 T 13-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 MADE_1008460 2cfdc89ea2ea4d4a800932d350faa451 379 SUPERFAMILY SSF53474 128 375 3.46E-31 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1008460 2cfdc89ea2ea4d4a800932d350faa451 379 Pfam PF12146 Serine aminopeptidase, S33 168 303 2.3E-9 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 MADE_1008460 2cfdc89ea2ea4d4a800932d350faa451 379 Gene3D G3DSA:3.40.50.1820 133 376 9.6E-31 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1006675 1e1f49b77bd5ae4ba7b4341f1d7725ae 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 4.9E-12 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 MADE_1006675 1e1f49b77bd5ae4ba7b4341f1d7725ae 308 Pfam PF03466 LysR substrate binding domain 117 297 2.2E-8 T 13-10-2018 IPR005119 LysR, substrate-binding MADE_1006675 1e1f49b77bd5ae4ba7b4341f1d7725ae 308 Gene3D G3DSA:3.40.190.290 102 304 3.3E-8 T 13-10-2018 MADE_1006675 1e1f49b77bd5ae4ba7b4341f1d7725ae 308 SUPERFAMILY SSF53850 107 302 9.23E-14 T 13-10-2018 MADE_1006675 1e1f49b77bd5ae4ba7b4341f1d7725ae 308 Gene3D G3DSA:1.10.10.10 9 99 1.5E-16 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006675 1e1f49b77bd5ae4ba7b4341f1d7725ae 308 SUPERFAMILY SSF46785 9 94 2.72E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001021125 ff5e234d0d43b46e5595d7965265e212 93 Gene3D G3DSA:1.10.238.10 20 83 5.9E-8 T 13-10-2018 MADE_000001021125 ff5e234d0d43b46e5595d7965265e212 93 Pfam PF13202 EF hand 60 77 0.0024 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_000001021125 ff5e234d0d43b46e5595d7965265e212 93 Pfam PF13202 EF hand 34 50 6.5E-4 T 13-10-2018 IPR002048 EF-hand domain GO:0005509 MADE_000001021125 ff5e234d0d43b46e5595d7965265e212 93 SUPERFAMILY SSF47473 29 79 2.03E-7 T 13-10-2018 IPR011992 EF-hand domain pair MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 SUPERFAMILY SSF46894 139 235 5.39E-27 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 233 1.7E-22 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 Pfam PF00072 Response regulator receiver domain 8 117 2.1E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 SUPERFAMILY SSF52172 5 128 3.42E-42 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 Gene3D G3DSA:1.10.10.10 131 240 1.4E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 SMART SM00862 157 233 1.3E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 Gene3D G3DSA:3.40.50.2300 1 127 4.9E-40 T 13-10-2018 MADE_1019780 6df0c2d2af6ad5c4e3c75b56ce27888a 240 SMART SM00448 6 117 2.5E-43 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1011100 728e490a7e5ee2c50b3724df92c05825 194 Gene3D G3DSA:1.20.1540.10 9 193 2.5E-12 T 13-10-2018 IPR035952 Rhomboid-like superfamily MADE_1011100 728e490a7e5ee2c50b3724df92c05825 194 SUPERFAMILY SSF144091 17 187 1.29E-24 T 13-10-2018 MADE_1011100 728e490a7e5ee2c50b3724df92c05825 194 TIGRFAM TIGR03902 rhom_GG_sort: rhombosortase 33 184 1.9E-53 T 13-10-2018 IPR023826 Rhomboid-like serine protease, proteobacteria MADE_1011100 728e490a7e5ee2c50b3724df92c05825 194 Pfam PF01694 Rhomboid family 43 188 7.1E-9 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 MADE_1019405 6b6d55b0b4247679ec8edb63d6f474e2 123 Pfam PF04247 Invasion gene expression up-regulator, SirB 3 120 5.0E-37 T 13-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MADE_1019405 6b6d55b0b4247679ec8edb63d6f474e2 123 PIRSF PIRSF005610 1 120 1.3E-26 T 13-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MADE_1005800 5b04b1f8f01ba34821e81b0b3e3d93f3 220 Gene3D G3DSA:3.40.50.10320 1 219 1.7E-51 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MADE_1005800 5b04b1f8f01ba34821e81b0b3e3d93f3 220 SUPERFAMILY SSF102588 1 216 5.75E-41 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 MADE_1005800 5b04b1f8f01ba34821e81b0b3e3d93f3 220 Pfam PF02585 GlcNAc-PI de-N-acetylase 1 123 9.8E-20 T 13-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.3E-24 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.3E-24 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.3E-24 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 PIRSF PIRSF002144 1 91 1.9E-31 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 Pfam PF00203 Ribosomal protein S19 3 83 6.9E-36 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 SUPERFAMILY SSF54570 3 83 9.94E-35 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.461 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 Gene3D G3DSA:3.30.860.10 1 91 9.1E-42 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002280 d2351d151089aa42144cc3ecb7ebdb0e 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 3.0E-45 T 13-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 MADE_1001905 c0797e626fcdd7151ca3436737c6f422 278 Pfam PF00551 Formyl transferase 71 156 2.6E-13 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1001905 c0797e626fcdd7151ca3436737c6f422 278 SUPERFAMILY SSF53328 1 185 9.68E-26 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1001905 c0797e626fcdd7151ca3436737c6f422 278 Gene3D G3DSA:3.40.50.12230 1 268 6.0E-36 T 13-10-2018 MADE_1010675 1521b1f5739030107e7c1414790b54e9 115 Gene3D G3DSA:1.10.10.370 45 115 7.9E-31 T 13-10-2018 MADE_1010675 1521b1f5739030107e7c1414790b54e9 115 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 9 115 1.5E-47 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE MADE_1010675 1521b1f5739030107e7c1414790b54e9 115 Gene3D G3DSA:3.30.1420.10 7 44 1.5E-8 T 13-10-2018 MADE_1010675 1521b1f5739030107e7c1414790b54e9 115 Pfam PF04358 DsrC like protein 10 115 3.4E-42 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE MADE_1010675 1521b1f5739030107e7c1414790b54e9 115 PIRSF PIRSF006223 8 115 1.2E-38 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE MADE_1010675 1521b1f5739030107e7c1414790b54e9 115 SUPERFAMILY SSF69721 6 115 1.03E-38 T 13-10-2018 IPR025526 DsrC-like domain superfamily MADE_000001022335 0ac2949dec0cecc494fac4e871183a78 348 Gene3D G3DSA:3.90.550.10 3 296 4.3E-39 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_000001022335 0ac2949dec0cecc494fac4e871183a78 348 Pfam PF00535 Glycosyl transferase family 2 42 166 3.3E-21 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_000001022335 0ac2949dec0cecc494fac4e871183a78 348 SUPERFAMILY SSF53448 38 262 2.46E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 9.9E-19 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 SMART SM00354 1 71 1.6E-29 T 13-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 Gene3D G3DSA:3.40.50.2300 56 305 1.7E-72 T 13-10-2018 MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 SUPERFAMILY SSF47413 1 60 2.82E-18 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 SUPERFAMILY SSF53822 61 331 3.53E-75 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 Pfam PF13377 Periplasmic binding protein-like domain 172 329 7.1E-31 T 13-10-2018 MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 Gene3D G3DSA:1.10.260.40 1 55 4.9E-23 T 13-10-2018 MADE_1019045 f9845191e9c14d9b0a2f89eab67a615e 333 Gene3D G3DSA:3.40.50.2300 160 289 1.7E-72 T 13-10-2018 MADE_000001023690 bed510ad12b828f589a965232de8d614 101 Gene3D G3DSA:3.10.290.10 1 79 4.7E-19 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 MADE_000001023690 bed510ad12b828f589a965232de8d614 101 SUPERFAMILY SSF55174 1 74 5.05E-13 T 13-10-2018 MADE_1005860 e222ca833244f468ef2f9e99a2fd7f1f 234 SUPERFAMILY SSF53448 3 225 1.69E-51 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1005860 e222ca833244f468ef2f9e99a2fd7f1f 234 Gene3D G3DSA:3.90.550.10 1 226 3.2E-61 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1005860 e222ca833244f468ef2f9e99a2fd7f1f 234 TIGRFAM TIGR03584 PseF: pseudaminic acid cytidylyltransferase 3 225 9.2E-88 T 13-10-2018 IPR020039 Pseudaminic acid cytidylyltransferase KEGG: 00520+2.7.7.81|MetaCyc: PWY-6143 MADE_1005860 e222ca833244f468ef2f9e99a2fd7f1f 234 Pfam PF02348 Cytidylyltransferase 3 199 2.0E-28 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 MADE_1006770 26cc53ad4b3170e87c58473c38b41f02 602 Pfam PF13584 Oxygen tolerance 22 469 2.0E-103 T 13-10-2018 IPR025738 Aerotolerance-related protein BatD MADE_1004360 5b51695dbe891422909336df496029e6 299 Gene3D G3DSA:3.20.20.70 2 299 1.6E-125 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1004360 5b51695dbe891422909336df496029e6 299 Pfam PF00274 Fructose-bisphosphate aldolase class-I 20 204 1.0E-8 T 13-10-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1004360 5b51695dbe891422909336df496029e6 299 SUPERFAMILY SSF51569 7 297 3.66E-93 T 13-10-2018 MADE_000001022340 bbab35883dd5512572ada354a44a619c 225 SUPERFAMILY SSF52540 25 212 7.77E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022340 bbab35883dd5512572ada354a44a619c 225 Gene3D G3DSA:3.40.50.300 23 225 2.9E-28 T 13-10-2018 MADE_1018465 a43a583aedc3b1fd66d2b22daf371a4d 271 Pfam PF01061 ABC-2 type transporter 24 233 1.5E-40 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 MADE_1018465 a43a583aedc3b1fd66d2b22daf371a4d 271 PIRSF PIRSF006648 1 267 6.2E-25 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1018465 a43a583aedc3b1fd66d2b22daf371a4d 271 PRINTS PR00164 ABC-2 type transport system membrane protein signature 191 210 4.8E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1018465 a43a583aedc3b1fd66d2b22daf371a4d 271 PRINTS PR00164 ABC-2 type transport system membrane protein signature 117 142 4.8E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1018465 a43a583aedc3b1fd66d2b22daf371a4d 271 PRINTS PR00164 ABC-2 type transport system membrane protein signature 73 95 4.8E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1018465 a43a583aedc3b1fd66d2b22daf371a4d 271 PRINTS PR00164 ABC-2 type transport system membrane protein signature 154 178 4.8E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 MADE_1004055 1126d4b40d0e7f35babe6c8f4e471471 122 PIRSF PIRSF016789 2 122 2.2E-32 T 13-10-2018 IPR007401 Protein of unknown function DUF454 MADE_1004055 1126d4b40d0e7f35babe6c8f4e471471 122 Pfam PF04304 Protein of unknown function (DUF454) 3 117 4.2E-34 T 13-10-2018 IPR007401 Protein of unknown function DUF454 MADE_000001022455 141153e4bae97a0640cd2aca23086f3e 319 Pfam PF05971 Protein of unknown function (DUF890) 1 319 2.4E-111 T 13-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 MADE_000001022455 141153e4bae97a0640cd2aca23086f3e 319 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 1 319 48.181 T 13-10-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 MADE_000001022455 141153e4bae97a0640cd2aca23086f3e 319 PIRSF PIRSF029038 1 319 1.8E-125 T 13-10-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 MADE_000001022455 141153e4bae97a0640cd2aca23086f3e 319 SUPERFAMILY SSF53335 36 319 1.01E-20 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1014295 43fb5a0abc2237db206dd434b5e11e14 320 Pfam PF01774 UreD urease accessory protein 75 293 8.1E-41 T 13-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MADE_1014295 43fb5a0abc2237db206dd434b5e11e14 320 Hamap MF_01384 Urease accessory protein UreD [ureD]. 33 304 24.864 T 13-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 MADE_1019745 d7c0a1297d432312d81e9653fd10e9a3 271 PIRSF PIRSF031679 1 270 9.1E-96 T 13-10-2018 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted MADE_1019745 d7c0a1297d432312d81e9653fd10e9a3 271 Gene3D G3DSA:3.40.50.150 27 228 4.5E-17 T 13-10-2018 MADE_1019745 d7c0a1297d432312d81e9653fd10e9a3 271 SUPERFAMILY SSF53335 38 227 1.32E-11 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1018445 6147e52c9a5d206badc620178344e80a 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 67 1.2E-9 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 MADE_1018445 6147e52c9a5d206badc620178344e80a 282 Gene3D G3DSA:3.40.50.620 1 179 1.0E-80 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1018445 6147e52c9a5d206badc620178344e80a 282 Gene3D G3DSA:3.30.1300.10 181 281 2.4E-28 T 13-10-2018 MADE_1018445 6147e52c9a5d206badc620178344e80a 282 Pfam PF02569 Pantoate-beta-alanine ligase 2 278 4.3E-106 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MADE_1018445 6147e52c9a5d206badc620178344e80a 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 39.557 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MADE_1018445 6147e52c9a5d206badc620178344e80a 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 280 2.1E-102 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 MADE_1018445 6147e52c9a5d206badc620178344e80a 282 SUPERFAMILY SSF52374 1 280 1.64E-106 T 13-10-2018 MADE_1019235 8e684a28e2c6c4f9157e6fa84634985f 340 Gene3D G3DSA:3.40.50.2300 145 331 1.7E-32 T 13-10-2018 MADE_1019235 8e684a28e2c6c4f9157e6fa84634985f 340 Pfam PF04392 ABC transporter substrate binding protein 47 337 5.8E-16 T 13-10-2018 IPR007487 ABC transporter, substrate-binding protein MADE_1019235 8e684a28e2c6c4f9157e6fa84634985f 340 Gene3D G3DSA:3.40.50.2300 59 309 1.7E-32 T 13-10-2018 MADE_1020365 00fdc107ed4f8dc38393c9842ded8a08 104 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 28 77 1.9E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1020365 00fdc107ed4f8dc38393c9842ded8a08 104 SUPERFAMILY SSF47413 20 78 4.79E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1020365 00fdc107ed4f8dc38393c9842ded8a08 104 Gene3D G3DSA:1.10.260.40 7 88 7.7E-10 T 13-10-2018 MADE_000001021660 c390fcaae7c15615038ebaacde0d76aa 71 Pfam PF09656 Putative transmembrane protein (PGPGW) 2 51 3.3E-7 T 13-10-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane MADE_1002810 31bcc710a87691cc8e447e9dbc03711c 79 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 8.7E-21 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MADE_1002810 31bcc710a87691cc8e447e9dbc03711c 79 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 78 24.911 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 MADE_1002810 31bcc710a87691cc8e447e9dbc03711c 79 Pfam PF02416 mttA/Hcf106 family 4 59 8.6E-15 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 MADE_1006975 54b01a27082bcbc8e49f704b647e6a70 118 Pfam PF04355 SmpA / OmlA family 31 102 4.7E-25 T 13-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 MADE_1006975 54b01a27082bcbc8e49f704b647e6a70 118 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 1 110 27.39 T 13-10-2018 IPR026592 Outer membrane protein assembly factor BamE MADE_1006975 54b01a27082bcbc8e49f704b647e6a70 118 Gene3D G3DSA:3.30.1450.10 30 115 3.1E-24 T 13-10-2018 IPR037873 BamE-like MADE_000001023165 67d02ba8c8a7c9f6492f8ce79bbb732e 450 Pfam PF05787 Bacterial protein of unknown function (DUF839) 145 437 1.3E-56 T 13-10-2018 IPR008557 Protein of unknown function DUF839 MADE_000001023165 67d02ba8c8a7c9f6492f8ce79bbb732e 450 Pfam PF05787 Bacterial protein of unknown function (DUF839) 36 137 6.6E-12 T 13-10-2018 IPR008557 Protein of unknown function DUF839 MADE_000001023165 67d02ba8c8a7c9f6492f8ce79bbb732e 450 SUPERFAMILY SSF63829 191 432 1.42E-10 T 13-10-2018 MADE_1014420 614c44f545e6811981a9d6b12d380ba1 278 Pfam PF13280 WYL domain 116 255 1.2E-11 T 13-10-2018 IPR026881 WYL domain MADE_1014420 614c44f545e6811981a9d6b12d380ba1 278 PIRSF PIRSF015558 2 276 8.2E-65 T 13-10-2018 IPR016634 WYL domain protein, s026 type MADE_1016075 1350917dfbf7defda20838db497c4660 194 Pfam PF06271 RDD family 39 177 6.0E-16 T 13-10-2018 IPR010432 RDD MADE_1012390 26a2f55fabf413c8731fcb7da9e19953 418 Gene3D G3DSA:3.40.50.150 140 413 2.6E-99 T 13-10-2018 MADE_1012390 26a2f55fabf413c8731fcb7da9e19953 418 PIRSF PIRSF003085 17 417 2.1E-122 T 13-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 MADE_1012390 26a2f55fabf413c8731fcb7da9e19953 418 SUPERFAMILY SSF53335 21 361 1.49E-92 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1012390 26a2f55fabf413c8731fcb7da9e19953 418 Pfam PF02353 Mycolic acid cyclopropane synthetase 133 403 1.7E-85 T 13-10-2018 MADE_1007765 5f4228a1a21e4f6138ed04efaea84bf9 136 SUPERFAMILY SSF54197 3 133 1.34E-32 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1007765 5f4228a1a21e4f6138ed04efaea84bf9 136 Gene3D G3DSA:3.30.428.10 1 135 3.2E-39 T 13-10-2018 IPR036265 HIT-like superfamily MADE_1007765 5f4228a1a21e4f6138ed04efaea84bf9 136 PIRSF PIRSF000714 1 136 1.2E-50 T 13-10-2018 IPR026026 Histidine triad hydrolase, Hint-type MADE_1007765 5f4228a1a21e4f6138ed04efaea84bf9 136 Pfam PF01230 HIT domain 9 97 4.9E-13 T 13-10-2018 IPR001310 Histidine triad (HIT) protein MADE_000001023095 b4a5fbccfca3a94186182e289d301772 88 Pfam PF13937 Domain of unknown function (DUF4212) 9 86 4.2E-34 T 13-10-2018 IPR019886 Sodium symporter small subunit, predicted MADE_000001023095 b4a5fbccfca3a94186182e289d301772 88 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 11 87 7.6E-36 T 13-10-2018 IPR019886 Sodium symporter small subunit, predicted MADE_1001525 adcdcf09b1d613c61558124c77a061a8 278 SUPERFAMILY SSF53328 1 179 6.41E-27 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1001525 adcdcf09b1d613c61558124c77a061a8 278 Gene3D G3DSA:3.40.50.12230 1 268 1.6E-36 T 13-10-2018 MADE_1001525 adcdcf09b1d613c61558124c77a061a8 278 Pfam PF00551 Formyl transferase 64 156 1.4E-13 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 MADE_1016465 01a8d8cae3c7fd73200898d80b03abdb 172 Pfam PF00294 pfkB family carbohydrate kinase 13 155 1.3E-24 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB MADE_1016465 01a8d8cae3c7fd73200898d80b03abdb 172 Gene3D G3DSA:3.40.1190.20 6 162 2.7E-37 T 13-10-2018 IPR029056 Ribokinase-like MADE_1016465 01a8d8cae3c7fd73200898d80b03abdb 172 SUPERFAMILY SSF53613 9 158 1.12E-35 T 13-10-2018 IPR029056 Ribokinase-like MADE_1019965 2f6830836d5cc7760d1f95ea853fa4bd 82 Hamap MF_00715 Protein SlyX [slyX]. 15 82 15.592 T 13-10-2018 IPR007236 SlyX MADE_1019965 2f6830836d5cc7760d1f95ea853fa4bd 82 Pfam PF04102 SlyX 19 82 8.2E-23 T 13-10-2018 IPR007236 SlyX MADE_1010145 112ede33b9c91d13bd430faf30553057 491 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 476 1.1E-135 T 13-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 MADE_1010145 112ede33b9c91d13bd430faf30553057 491 Pfam PF03553 Na+/H+ antiporter family 166 473 7.5E-58 T 13-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MADE_1010960 1f9eed0b5a0d9fae908c9e750faf13a5 393 Pfam PF05762 VWA domain containing CoxE-like protein 186 273 9.4E-7 T 13-10-2018 IPR008912 Uncharacterised protein family CoxE-like MADE_1014000 cae877fe6db6d6919287d77e555f5483 179 PIRSF PIRSF002161 1 179 8.9E-67 T 13-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1014000 cae877fe6db6d6919287d77e555f5483 179 Pfam PF00281 Ribosomal protein L5 24 80 1.3E-27 T 13-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1014000 cae877fe6db6d6919287d77e555f5483 179 SUPERFAMILY SSF55282 4 179 2.31E-79 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1014000 cae877fe6db6d6919287d77e555f5483 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.8E-41 T 13-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1014000 cae877fe6db6d6919287d77e555f5483 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 13-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1014000 cae877fe6db6d6919287d77e555f5483 179 Gene3D G3DSA:3.30.1440.10 1 179 1.2E-80 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1014000 cae877fe6db6d6919287d77e555f5483 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.624 T 13-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1004830 1d8176fc46aae6cd74f510f4de301236 224 Pfam PF00005 ABC transporter 22 152 9.1E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004830 1d8176fc46aae6cd74f510f4de301236 224 Gene3D G3DSA:3.40.50.300 1 223 1.3E-37 T 13-10-2018 MADE_1004830 1d8176fc46aae6cd74f510f4de301236 224 SUPERFAMILY SSF52540 2 209 1.81E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004830 1d8176fc46aae6cd74f510f4de301236 224 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1004830 1d8176fc46aae6cd74f510f4de301236 224 SMART SM00382 30 214 2.8E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1019795 287b2fde2f17a5c6ae489d8fa589ebcf 392 Gene3D G3DSA:1.20.1250.20 197 385 4.6E-21 T 13-10-2018 MADE_1019795 287b2fde2f17a5c6ae489d8fa589ebcf 392 Gene3D G3DSA:1.20.1250.20 2 188 6.0E-21 T 13-10-2018 MADE_1019795 287b2fde2f17a5c6ae489d8fa589ebcf 392 SUPERFAMILY SSF103473 3 388 6.8E-44 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1019795 287b2fde2f17a5c6ae489d8fa589ebcf 392 Pfam PF07690 Major Facilitator Superfamily 10 325 4.4E-23 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1007815 818eb278bdec36367fff5ced84899265 121 SUPERFAMILY SSF54593 5 117 2.55E-18 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1007815 818eb278bdec36367fff5ced84899265 121 Gene3D G3DSA:3.10.180.10 2 120 2.2E-24 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1014340 8fb735f31fd8c4be689d82f316efb583 503 Gene3D G3DSA:1.10.3290.10 270 503 1.4E-42 T 13-10-2018 IPR036597 Fido-like domain superfamily MADE_1014340 8fb735f31fd8c4be689d82f316efb583 503 SUPERFAMILY SSF140931 332 502 1.23E-28 T 13-10-2018 IPR036597 Fido-like domain superfamily MADE_1014340 8fb735f31fd8c4be689d82f316efb583 503 Pfam PF02661 Fic/DOC family 389 461 8.5E-11 T 13-10-2018 IPR003812 Fido domain MADE_1000415 4556a34b2e34678279e124e751789d3d 266 Pfam PF01925 Sulfite exporter TauE/SafE 7 259 1.3E-44 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MADE_1006350 59514f26d3552f1e335d275d9b9b347a 302 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 6 300 9.8E-98 T 13-10-2018 IPR020020 Luciferase-type oxidoreductase MADE_1006350 59514f26d3552f1e335d275d9b9b347a 302 SUPERFAMILY SSF51679 41 301 5.5E-49 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MADE_1006350 59514f26d3552f1e335d275d9b9b347a 302 Pfam PF00296 Luciferase-like monooxygenase 40 224 1.8E-28 T 13-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 MADE_1006350 59514f26d3552f1e335d275d9b9b347a 302 Gene3D G3DSA:3.20.20.30 3 302 5.3E-71 T 13-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 MADE_1013520 6a6c21317bd6d9aef5a3eb6dd2c353ab 157 SUPERFAMILY SSF54690 5 153 2.88E-43 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MADE_1013520 6a6c21317bd6d9aef5a3eb6dd2c353ab 157 Pfam PF02391 MoaE protein 11 123 5.9E-28 T 13-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MADE_1013520 6a6c21317bd6d9aef5a3eb6dd2c353ab 157 Gene3D G3DSA:3.90.1170.40 2 153 1.5E-40 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 MADE_1007520 a807561c1f8b513aba119b2682188fde 328 SUPERFAMILY SSF53448 3 257 4.13E-35 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1007520 a807561c1f8b513aba119b2682188fde 328 Pfam PF00535 Glycosyl transferase family 2 6 165 3.6E-23 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1007520 a807561c1f8b513aba119b2682188fde 328 Gene3D G3DSA:3.90.550.10 1 235 1.0E-41 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 164 331 1.8E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 SMART SM00091 36 101 5.1E-4 T 13-10-2018 IPR000014 PAS domain MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 SUPERFAMILY SSF55785 47 165 3.67E-9 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 SMART SM00267 157 333 1.4E-49 T 13-10-2018 IPR000160 GGDEF domain MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 Pfam PF13426 PAS domain 47 155 4.1E-7 T 13-10-2018 IPR000014 PAS domain MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 42 159 6.9E-8 T 13-10-2018 IPR000014 PAS domain MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 Pfam PF00990 Diguanylate cyclase, GGDEF domain 168 329 1.8E-45 T 13-10-2018 IPR000160 GGDEF domain MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 Gene3D G3DSA:3.30.70.270 158 333 9.3E-50 T 13-10-2018 MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 Gene3D G3DSA:3.30.450.20 34 157 2.0E-18 T 13-10-2018 MADE_1013320 1fb7d8cdb1491f9bd602cac645c02fab 333 SUPERFAMILY SSF55073 173 332 2.67E-43 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1016350 086f34c6118ab6196c501c6de0756e5e 99 Gene3D G3DSA:3.40.50.12740 1 95 1.7E-15 T 13-10-2018 MADE_1016350 086f34c6118ab6196c501c6de0756e5e 99 Pfam PF00072 Response regulator receiver domain 3 85 5.8E-15 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1016350 086f34c6118ab6196c501c6de0756e5e 99 SUPERFAMILY SSF52172 1 89 1.38E-16 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1014085 51d308f067e6c531cd74f99f8dc0ff49 196 Pfam PF11075 Protein of unknown function VcgC/VcgE (DUF2780) 11 189 2.9E-41 T 13-10-2018 IPR021302 Protein of unknown function DUF2780, VcgC/VcgE MADE_000001021290 1cb9514e66a2f534a755a5151cba2d01 147 Gene3D G3DSA:3.40.190.10 27 145 1.1E-5 T 13-10-2018 MADE_000001021290 1cb9514e66a2f534a755a5151cba2d01 147 SUPERFAMILY SSF53850 25 143 1.19E-6 T 13-10-2018 MADE_1016015 0e83cc7ae1eff0d97194387c33821f42 132 PIRSF PIRSF018193 1 132 7.9E-45 T 13-10-2018 IPR016716 Regulator of ribonuclease activity B MADE_1016015 0e83cc7ae1eff0d97194387c33821f42 132 SUPERFAMILY SSF89946 6 123 2.35E-36 T 13-10-2018 IPR036701 RraB-like superfamily MADE_1016015 0e83cc7ae1eff0d97194387c33821f42 132 Hamap MF_01888 Regulator of ribonuclease activity B [rraB]. 5 117 29.959 T 13-10-2018 IPR016716 Regulator of ribonuclease activity B MADE_1016015 0e83cc7ae1eff0d97194387c33821f42 132 Gene3D G3DSA:3.30.70.970 1 129 1.2E-45 T 13-10-2018 IPR036701 RraB-like superfamily MADE_1016015 0e83cc7ae1eff0d97194387c33821f42 132 Pfam PF06877 Regulator of ribonuclease activity B 13 113 3.7E-29 T 13-10-2018 IPR009671 Regulator of ribonuclease activity B domain MADE_1016995 fe4e22036522d6bca174b004e6135025 186 Pfam PF01625 Peptide methionine sulfoxide reductase 12 164 7.8E-67 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1016995 fe4e22036522d6bca174b004e6135025 186 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 9 168 38.02 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1016995 fe4e22036522d6bca174b004e6135025 186 Gene3D G3DSA:3.30.1060.10 1 173 3.7E-73 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1016995 fe4e22036522d6bca174b004e6135025 186 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 11 163 4.0E-62 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1016995 fe4e22036522d6bca174b004e6135025 186 SUPERFAMILY SSF55068 4 174 2.22E-75 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 MADE_1018170 3f9fab8cd16544e333f2c66ab435ad59 186 SMART SM00448 68 180 1.1E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1018170 3f9fab8cd16544e333f2c66ab435ad59 186 SUPERFAMILY SSF52172 67 185 6.97E-27 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1018170 3f9fab8cd16544e333f2c66ab435ad59 186 Pfam PF00072 Response regulator receiver domain 70 180 1.2E-17 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1018170 3f9fab8cd16544e333f2c66ab435ad59 186 SUPERFAMILY SSF46955 3 54 1.17E-5 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1018170 3f9fab8cd16544e333f2c66ab435ad59 186 Pfam PF12728 Helix-turn-helix domain 4 54 3.5E-8 T 13-10-2018 MADE_1018170 3f9fab8cd16544e333f2c66ab435ad59 186 Gene3D G3DSA:3.40.50.2300 64 186 3.7E-26 T 13-10-2018 MADE_1018170 3f9fab8cd16544e333f2c66ab435ad59 186 Gene3D G3DSA:1.10.1660.10 2 52 2.5E-5 T 13-10-2018 MADE_1015860 679f0ba4fdf6db12086fbde2fe549b8d 445 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 13 415 1.3E-133 T 13-10-2018 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 MADE_1015860 679f0ba4fdf6db12086fbde2fe549b8d 445 Gene3D G3DSA:1.20.1250.20 11 227 1.2E-49 T 13-10-2018 MADE_1015860 679f0ba4fdf6db12086fbde2fe549b8d 445 Pfam PF07690 Major Facilitator Superfamily 19 373 1.2E-14 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1015860 679f0ba4fdf6db12086fbde2fe549b8d 445 SUPERFAMILY SSF103473 6 420 3.53E-33 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1015860 679f0ba4fdf6db12086fbde2fe549b8d 445 Gene3D G3DSA:1.20.1250.20 232 422 1.5E-46 T 13-10-2018 MADE_1002470 8f5216ebb6de25d020a011a7e9a64960 238 Pfam PF11201 Protein of unknown function (DUF2982) 73 223 1.0E-58 T 13-10-2018 IPR021367 Protein of unknown function DUF2982 MADE_1009670 5fa42cccabe0f5a40929a0a2c5fcd7dd 508 SUPERFAMILY SSF53649 412 455 6.98E-6 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 MADE_1009670 5fa42cccabe0f5a40929a0a2c5fcd7dd 508 Pfam PF11893 Domain of unknown function (DUF3413) 8 256 1.3E-80 T 13-10-2018 IPR024588 Inner membrane protein YejM, N-terminal MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 Gene3D G3DSA:1.25.40.10 36 424 6.0E-29 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SUPERFAMILY SSF48452 39 261 8.35E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 Pfam PF13432 Tetratricopeptide repeat 848 895 0.0026 T 13-10-2018 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 Pfam PF13432 Tetratricopeptide repeat 781 840 8.3E-4 T 13-10-2018 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SUPERFAMILY SSF48452 274 461 8.54E-13 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SUPERFAMILY SSF48452 771 892 1.02E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SUPERFAMILY SSF48452 449 746 1.86E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 Gene3D G3DSA:1.25.40.10 448 562 3.9E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SMART SM00028 304 337 42.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SMART SM00028 710 743 190.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SMART SM00028 203 236 330.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SMART SM00028 508 541 180.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SMART SM00028 105 138 85.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SMART SM00028 237 270 370.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1013135 0ab36d6b303edea46ab2678d84b4bf7d 918 SMART SM00028 809 842 0.97 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 Gene3D G3DSA:3.40.50.300 2 281 6.0E-54 T 13-10-2018 MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 SUPERFAMILY SSF52540 297 523 3.17E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 Gene3D G3DSA:3.40.50.300 282 530 1.6E-53 T 13-10-2018 MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 SUPERFAMILY SSF52540 4 239 6.13E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 Pfam PF00005 ABC transporter 336 467 2.2E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 SMART SM00382 26 238 1.4E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 SMART SM00382 344 512 4.0E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 Pfam PF00005 ABC transporter 18 184 2.7E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004540 cce24dabef2bfcc25fa459245cd044a9 530 Pfam PF12848 ABC transporter 224 306 4.6E-21 T 13-10-2018 IPR032781 ABC-transporter extension domain MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 Pfam PF00472 RF-1 domain 145 254 1.1E-42 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 SUPERFAMILY SSF75620 1 281 1.7E-123 T 13-10-2018 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 SMART SM00937 2 112 7.6E-59 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 282 31.956 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 Gene3D G3DSA:3.30.160.20 143 238 3.5E-97 T 13-10-2018 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 162 178 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 Pfam PF03462 PCRF domain 6 136 9.4E-46 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 280 6.0E-148 T 13-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 MADE_1006465 a515ad467037d3702faa506ad7a699f7 282 Gene3D G3DSA:3.30.70.1660 47 275 3.5E-97 T 13-10-2018 MADE_1002235 815c7b506f383784a849ea964209c06e 153 Pfam PF06172 Cupin superfamily (DUF985) 5 132 8.3E-41 T 13-10-2018 IPR009327 Cupin domain of unknown function DUF985 MADE_1002235 815c7b506f383784a849ea964209c06e 153 SUPERFAMILY SSF51182 4 142 4.15E-45 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1002235 815c7b506f383784a849ea964209c06e 153 Gene3D G3DSA:2.60.120.10 1 150 3.6E-44 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_000001021620 368b01e9a9a36aad1e019d0b0f631ddd 903 Pfam PF00593 TonB dependent receptor 289 900 1.1E-33 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_000001021620 368b01e9a9a36aad1e019d0b0f631ddd 903 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 38 - T 13-10-2018 IPR010916 TonB box, conserved site MADE_000001021620 368b01e9a9a36aad1e019d0b0f631ddd 903 Gene3D G3DSA:2.170.130.10 21 166 9.3E-27 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_000001021620 368b01e9a9a36aad1e019d0b0f631ddd 903 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 158 3.5E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_000001021620 368b01e9a9a36aad1e019d0b0f631ddd 903 SUPERFAMILY SSF56935 21 902 1.36E-95 T 13-10-2018 MADE_000001023145 32a3c7bd8ab7e56c54980fba07bc109f 384 PRINTS PR00173 Glutamate-aspartate symporter signature 51 76 5.8E-6 T 13-10-2018 MADE_000001023145 32a3c7bd8ab7e56c54980fba07bc109f 384 PRINTS PR00173 Glutamate-aspartate symporter signature 191 210 5.8E-6 T 13-10-2018 MADE_000001023145 32a3c7bd8ab7e56c54980fba07bc109f 384 PRINTS PR00173 Glutamate-aspartate symporter signature 20 40 5.8E-6 T 13-10-2018 MADE_000001023145 32a3c7bd8ab7e56c54980fba07bc109f 384 PRINTS PR00173 Glutamate-aspartate symporter signature 294 313 5.8E-6 T 13-10-2018 MADE_000001023145 32a3c7bd8ab7e56c54980fba07bc109f 384 Pfam PF02690 Na+/Pi-cotransporter 33 149 3.4E-20 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 MADE_000001023145 32a3c7bd8ab7e56c54980fba07bc109f 384 Pfam PF02690 Na+/Pi-cotransporter 218 336 3.4E-19 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 375 385 - T 13-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 Gene3D G3DSA:2.60.120.380 460 555 5.0E-36 T 13-10-2018 MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 474 541 5.5E-14 T 13-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 SUPERFAMILY SSF52743 158 438 1.96E-84 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 223 233 - T 13-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 Gene3D G3DSA:3.40.50.200 161 445 2.5E-84 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 PRINTS PR00723 Subtilisin serine protease family (S8) signature 178 197 3.5E-17 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 PRINTS PR00723 Subtilisin serine protease family (S8) signature 219 232 3.5E-17 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 PRINTS PR00723 Subtilisin serine protease family (S8) signature 374 390 3.5E-17 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 SUPERFAMILY SSF54897 64 153 5.95E-9 T 13-10-2018 MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 Pfam PF00082 Subtilase family 182 425 5.4E-52 T 13-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 MADE_1018005 25381e0efaffddb7534f33bf154a3b10 556 Gene3D G3DSA:3.30.70.80 59 160 3.6E-14 T 13-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 MADE_1001665 a87f6fd4145fb270d3e3d4755ba4e69d 144 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 17 118 1.0E-12 T 13-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal MADE_1001665 a87f6fd4145fb270d3e3d4755ba4e69d 144 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 17 125 1.8E-22 T 13-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal MADE_1001665 a87f6fd4145fb270d3e3d4755ba4e69d 144 Gene3D G3DSA:3.30.1370.140 13 112 4.3E-25 T 13-10-2018 IPR038527 HupH, C-terminal domain superfamily MADE_1003330 112733367d95db9bfaf5d8399e7d72bc 324 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site MADE_1003330 112733367d95db9bfaf5d8399e7d72bc 324 SUPERFAMILY SSF48576 5 323 5.92E-98 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily MADE_1003330 112733367d95db9bfaf5d8399e7d72bc 324 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site MADE_1003330 112733367d95db9bfaf5d8399e7d72bc 324 Gene3D G3DSA:1.10.600.10 1 324 7.1E-112 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily MADE_1003330 112733367d95db9bfaf5d8399e7d72bc 324 Pfam PF00348 Polyprenyl synthetase 32 262 5.6E-75 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MADE_1015085 3c31f2f45b56b1d662a0bcf899a18118 213 Pfam PF13646 HEAT repeats 119 186 1.6E-8 T 13-10-2018 MADE_1015085 3c31f2f45b56b1d662a0bcf899a18118 213 SUPERFAMILY SSF48371 25 185 1.3E-11 T 13-10-2018 IPR016024 Armadillo-type fold MADE_1015085 3c31f2f45b56b1d662a0bcf899a18118 213 Gene3D G3DSA:1.25.10.10 14 200 6.9E-14 T 13-10-2018 IPR011989 Armadillo-like helical MADE_1014055 74d0389dd6de2131383c0be46053c1a3 149 Pfam PF07813 LTXXQ motif family protein 35 136 1.5E-10 T 13-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 MADE_1014055 74d0389dd6de2131383c0be46053c1a3 149 Gene3D G3DSA:1.20.120.1490 35 148 8.9E-16 T 13-10-2018 MADE_1006495 490fec4882d1311627bf42c06a6202d7 532 SUPERFAMILY SSF55931 11 519 1.05E-189 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 MADE_1006495 490fec4882d1311627bf42c06a6202d7 532 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 11 522 4.8E-188 T 13-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MADE_1006495 490fec4882d1311627bf42c06a6202d7 532 Gene3D G3DSA:3.30.590.20 22 529 2.9E-184 T 13-10-2018 MADE_1006495 490fec4882d1311627bf42c06a6202d7 532 Pfam PF04262 Glutamate-cysteine ligase 13 385 1.9E-164 T 13-10-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MADE_1006495 490fec4882d1311627bf42c06a6202d7 532 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 532 203.529 T 13-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 MADE_1004405 97f262d3a0a0b1d2e66b9d6abbbd3ad5 238 PIRSF PIRSF003107 7 227 3.6E-60 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MADE_1004405 97f262d3a0a0b1d2e66b9d6abbbd3ad5 238 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 14 221 2.0E-60 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 MADE_1004405 97f262d3a0a0b1d2e66b9d6abbbd3ad5 238 SUPERFAMILY SSF109755 13 233 1.57E-62 T 13-10-2018 MADE_1004405 97f262d3a0a0b1d2e66b9d6abbbd3ad5 238 Gene3D G3DSA:1.20.58.220 1 118 1.3E-35 T 13-10-2018 IPR038078 PhoU-like domain superfamily MADE_1004405 97f262d3a0a0b1d2e66b9d6abbbd3ad5 238 Gene3D G3DSA:1.20.58.220 123 236 1.5E-25 T 13-10-2018 IPR038078 PhoU-like domain superfamily MADE_1004405 97f262d3a0a0b1d2e66b9d6abbbd3ad5 238 Pfam PF01895 PhoU domain 131 213 4.5E-14 T 13-10-2018 IPR026022 PhoU domain MADE_1004405 97f262d3a0a0b1d2e66b9d6abbbd3ad5 238 Pfam PF01895 PhoU domain 26 112 6.4E-18 T 13-10-2018 IPR026022 PhoU domain MADE_1009600 1da314ad58fb6391c172667ffd58f1f7 340 Pfam PF01343 Peptidase family S49 154 293 2.0E-40 T 13-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 MADE_1009600 1da314ad58fb6391c172667ffd58f1f7 340 SUPERFAMILY SSF52096 93 291 2.45E-25 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1009600 1da314ad58fb6391c172667ffd58f1f7 340 Pfam PF08496 Peptidase family S49 N-terminal 2 150 7.7E-56 T 13-10-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 MADE_1009600 1da314ad58fb6391c172667ffd58f1f7 340 Gene3D G3DSA:3.90.226.10 126 293 1.2E-38 T 13-10-2018 MADE_1009600 1da314ad58fb6391c172667ffd58f1f7 340 Gene3D G3DSA:3.40.1750.20 194 258 1.2E-38 T 13-10-2018 MADE_1007260 dcff5916f20aa1f4a990ef47e35977ab 466 Gene3D G3DSA:3.90.1150.10 34 427 5.9E-117 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1007260 dcff5916f20aa1f4a990ef47e35977ab 466 Gene3D G3DSA:3.40.640.10 50 323 5.9E-117 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1007260 dcff5916f20aa1f4a990ef47e35977ab 466 Pfam PF00155 Aminotransferase class I and II 39 429 3.9E-50 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1007260 dcff5916f20aa1f4a990ef47e35977ab 466 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 270 279 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 MADE_1007260 dcff5916f20aa1f4a990ef47e35977ab 466 SUPERFAMILY SSF53383 3 431 2.31E-89 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 TIGRFAM TIGR02519 pilus_MshL: pilus (MSHA type) biogenesis protein MshL 258 560 7.9E-87 T 13-10-2018 IPR013358 Pilus biogenesis, MshL MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 Pfam PF00263 Bacterial type II and III secretion system protein 384 561 1.1E-41 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 Gene3D G3DSA:3.55.50.30 60 158 1.8E-11 T 13-10-2018 MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 PRINTS PR00811 Bacterial general secretion pathway protein D signature 379 403 1.3E-16 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 PRINTS PR00811 Bacterial general secretion pathway protein D signature 548 562 1.3E-16 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 PRINTS PR00811 Bacterial general secretion pathway protein D signature 292 302 1.3E-16 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 PRINTS PR00811 Bacterial general secretion pathway protein D signature 525 543 1.3E-16 T 13-10-2018 IPR001775 GspD/PilQ family MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 Pfam PF07655 Secretin N-terminal domain 154 263 8.0E-23 T 13-10-2018 IPR011514 Secretin, N-terminal GO:0009297|GO:0019867 MADE_1001230 e2393f912ed855168f1ed02f30a1b937 582 SMART SM00965 102 150 4.1E-4 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 MADE_000001021200 a5b6a33b205c8d4bd7f9e3e0b94b0aa7 139 TIGRFAM TIGR02801 tolR: protein TolR 10 136 1.2E-45 T 13-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 MADE_000001021200 a5b6a33b205c8d4bd7f9e3e0b94b0aa7 139 Hamap MF_02203 Tol-Pal system protein TolR [tolR]. 3 136 31.086 T 13-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 MADE_000001021200 a5b6a33b205c8d4bd7f9e3e0b94b0aa7 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 137 4.4E-28 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MADE_000001021200 a5b6a33b205c8d4bd7f9e3e0b94b0aa7 139 Gene3D G3DSA:3.30.420.270 56 128 3.7E-26 T 13-10-2018 MADE_1013480 0898e985fa24f0932ccb85d817dc3bf7 860 Pfam PF00593 TonB dependent receptor 276 857 2.5E-38 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1013480 0898e985fa24f0932ccb85d817dc3bf7 860 Pfam PF07715 TonB-dependent Receptor Plug Domain 60 168 1.8E-14 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1013480 0898e985fa24f0932ccb85d817dc3bf7 860 SUPERFAMILY SSF56935 40 860 8.42E-103 T 13-10-2018 MADE_1013480 0898e985fa24f0932ccb85d817dc3bf7 860 Gene3D G3DSA:2.40.170.20 52 525 1.4E-67 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1013480 0898e985fa24f0932ccb85d817dc3bf7 860 Gene3D G3DSA:2.40.170.20 552 860 3.9E-55 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 689 26.023 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 317 333 9.1E-36 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 9.1E-36 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 9.1E-36 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 245 260 9.1E-36 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 9.1E-36 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 SUPERFAMILY SSF109604 339 490 2.67E-12 T 13-10-2018 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 SMART SM00836 584 686 0.0031 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 Pfam PF05746 DALR anticodon binding domain 581 683 6.4E-12 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 549 1.5E-207 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 SUPERFAMILY SSF47323 583 680 9.16E-7 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 Gene3D G3DSA:1.10.730.10 574 684 2.7E-6 T 13-10-2018 MADE_1000035 3867ceed78c36ce2b3b4d36803b2fd46 692 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 3 689 5.4E-264 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 MADE_1011990 a68186d9b44a0af28cb3a22ae30ad441 114 Gene3D G3DSA:3.10.180.10 3 113 1.0E-13 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1011990 a68186d9b44a0af28cb3a22ae30ad441 114 SUPERFAMILY SSF54593 8 111 1.01E-15 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1004865 6fb50a377f9e2968bfe0e1957ab837ed 296 Gene3D G3DSA:3.90.550.10 1 296 4.5E-88 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1004865 6fb50a377f9e2968bfe0e1957ab837ed 296 Pfam PF00483 Nucleotidyl transferase 6 277 3.5E-28 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 MADE_1004865 6fb50a377f9e2968bfe0e1957ab837ed 296 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 273 1.4E-110 T 13-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 MADE_1004865 6fb50a377f9e2968bfe0e1957ab837ed 296 SUPERFAMILY SSF53448 5 285 5.18E-63 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1003490 d1e2f4258ea24567d908a6824467483e 238 Gene3D G3DSA:3.30.2350.10 6 225 5.7E-70 T 13-10-2018 MADE_1003490 d1e2f4258ea24567d908a6824467483e 238 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 62 76 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1003490 d1e2f4258ea24567d908a6824467483e 238 Pfam PF00849 RNA pseudouridylate synthase 25 175 7.2E-30 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1003490 d1e2f4258ea24567d908a6824467483e 238 SUPERFAMILY SSF55120 16 227 9.6E-63 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 PRINTS PR01100 Shikimate kinase family signature 31 44 1.8E-27 T 13-10-2018 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 PRINTS PR01100 Shikimate kinase family signature 59 67 1.8E-27 T 13-10-2018 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 PRINTS PR01100 Shikimate kinase family signature 77 86 1.8E-27 T 13-10-2018 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 PRINTS PR01100 Shikimate kinase family signature 7 22 1.8E-27 T 13-10-2018 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 PRINTS PR01100 Shikimate kinase family signature 98 115 1.8E-27 T 13-10-2018 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 SUPERFAMILY SSF52540 4 168 1.33E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 Pfam PF01202 Shikimate kinase 13 169 4.0E-56 T 13-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 13-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 Hamap MF_00109 Shikimate kinase [aroK]. 4 170 29.025 T 13-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 MADE_1002565 6dce34e13f36a2378c2cdb5b19e23ca6 171 Gene3D G3DSA:3.40.50.300 1 170 2.3E-57 T 13-10-2018 MADE_1015775 00ec5cc4ad866d9377ebeec374d22786 315 SMART SM00644 29 196 9.6E-21 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MADE_1015775 00ec5cc4ad866d9377ebeec374d22786 315 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 40 197 5.1E-27 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MADE_1015775 00ec5cc4ad866d9377ebeec374d22786 315 Gene3D G3DSA:2.30.30.40 242 308 5.3E-13 T 13-10-2018 MADE_1015775 00ec5cc4ad866d9377ebeec374d22786 315 SMART SM00287 246 307 7.5E-7 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type MADE_1015775 00ec5cc4ad866d9377ebeec374d22786 315 SUPERFAMILY SSF55846 24 208 7.07E-44 T 13-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 MADE_1015775 00ec5cc4ad866d9377ebeec374d22786 315 Pfam PF08239 Bacterial SH3 domain 255 304 1.8E-8 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type MADE_1016120 fd5ac82f0c348aa854ef2e4c925b4f85 86 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 1 75 1.1E-16 T 13-10-2018 IPR022789 Antitoxin ParD MADE_1016120 fd5ac82f0c348aa854ef2e4c925b4f85 86 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 3 54 2.0E-10 T 13-10-2018 IPR022789 Antitoxin ParD MADE_1016120 fd5ac82f0c348aa854ef2e4c925b4f85 86 SUPERFAMILY SSF47598 1 40 7.45E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1016120 fd5ac82f0c348aa854ef2e4c925b4f85 86 Gene3D G3DSA:1.10.8.1250 6 83 3.3E-14 T 13-10-2018 IPR038296 Antitoxin ParD superfamily MADE_1015760 579c9da7a81db592f49b8f5f01027ae9 542 Pfam PF03703 Bacterial PH domain 454 526 1.1E-8 T 13-10-2018 IPR005182 Domain of unknown function DUF304 MADE_1015760 579c9da7a81db592f49b8f5f01027ae9 542 Pfam PF03703 Bacterial PH domain 89 164 9.0E-17 T 13-10-2018 IPR005182 Domain of unknown function DUF304 MADE_1015760 579c9da7a81db592f49b8f5f01027ae9 542 PIRSF PIRSF026631 28 536 6.7E-55 T 13-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 SUPERFAMILY SSF53383 489 962 1.14E-98 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 25 961 0.0 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 Gene3D G3DSA:3.90.1150.10 775 913 6.2E-41 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 Pfam PF02347 Glycine cleavage system P-protein 470 745 3.2E-7 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 Pfam PF02347 Glycine cleavage system P-protein 24 447 1.5E-183 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 Gene3D G3DSA:3.40.640.10 103 362 2.4E-103 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 Gene3D G3DSA:3.40.640.10 534 763 1.1E-60 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 SUPERFAMILY SSF53383 25 447 5.77E-100 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1014425 585513c54d1d62032757feae79f8b7f6 970 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 16 967 25.578 T 13-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 MADE_1000175 a594b770424591c30322ef20054ec4fb 263 Gene3D G3DSA:3.40.190.10 33 202 1.1E-6 T 13-10-2018 MADE_1000175 a594b770424591c30322ef20054ec4fb 263 Gene3D G3DSA:3.40.190.10 110 201 1.1E-6 T 13-10-2018 MADE_1000175 a594b770424591c30322ef20054ec4fb 263 SUPERFAMILY SSF53850 33 186 6.4E-12 T 13-10-2018 MADE_1004195 56c61dfdc07d9b4385673166b924e074 184 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 24 166 8.1E-41 T 13-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MADE_1004195 56c61dfdc07d9b4385673166b924e074 184 Gene3D G3DSA:2.60.450.10 23 163 1.9E-36 T 13-10-2018 MADE_1004195 56c61dfdc07d9b4385673166b924e074 184 Pfam PF03968 OstA-like protein 34 143 7.7E-23 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal MADE_1004195 56c61dfdc07d9b4385673166b924e074 184 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 5 166 21.397 T 13-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 MADE_1008740 e0d074a7f7de90fd7a4c507b781cf328 185 SUPERFAMILY SSF50475 1 185 7.5E-37 T 13-10-2018 MADE_1008740 e0d074a7f7de90fd7a4c507b781cf328 185 Gene3D G3DSA:2.30.110.10 1 185 5.5E-50 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_1008740 e0d074a7f7de90fd7a4c507b781cf328 185 TIGRFAM TIGR04026 PPOX_FMN_cyano: PPOX class probable FMN-dependent enzyme, alr4036 family 1 185 6.4E-70 T 13-10-2018 IPR024015 Pyridoxamine 5'-phosphate oxidase, probable FMN-dependent, Alr4036 family KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282 MADE_1008740 e0d074a7f7de90fd7a4c507b781cf328 185 Pfam PF12766 Pyridoxamine 5'-phosphate oxidase 1 93 9.3E-23 T 13-10-2018 IPR024624 Pyridoxamine 5'-phosphate oxidase, Alr4036 family, FMN-binding domain GO:0010181 MADE_1005780 2893695591b1c300951e1fd9434640b5 471 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 234 452 6.6E-41 T 13-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 MADE_1005780 2893695591b1c300951e1fd9434640b5 471 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 114 4.4E-14 T 13-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 MADE_1005780 2893695591b1c300951e1fd9434640b5 471 Pfam PF07196 Flagellin hook IN motif 142 186 9.5E-7 T 13-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 MADE_1001005 ca1d98989594198a48e140a8c72a5b41 231 Gene3D G3DSA:3.30.450.40 58 228 2.1E-34 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1001005 ca1d98989594198a48e140a8c72a5b41 231 Pfam PF04340 Protein of unknown function, DUF484 20 225 1.3E-42 T 13-10-2018 IPR007435 Protein of unknown function DUF484 MADE_000001023675 90b11c842d323f873cdb067a93986aca 197 Gene3D G3DSA:1.10.530.10 44 185 1.5E-17 T 13-10-2018 MADE_000001023675 90b11c842d323f873cdb067a93986aca 197 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 57 180 2.8E-17 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MADE_000001023675 90b11c842d323f873cdb067a93986aca 197 SMART SM00047 33 169 6.5E-4 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MADE_1015645 6c4b7d2ee78303b4cb4fdd141780f47f 191 Pfam PF04972 BON domain 124 190 1.5E-12 T 13-10-2018 IPR007055 BON domain MADE_1015645 6c4b7d2ee78303b4cb4fdd141780f47f 191 Pfam PF04972 BON domain 60 114 2.0E-12 T 13-10-2018 IPR007055 BON domain MADE_1015645 6c4b7d2ee78303b4cb4fdd141780f47f 191 SMART SM00749 51 115 69.0 T 13-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria MADE_1015645 6c4b7d2ee78303b4cb4fdd141780f47f 191 SMART SM00749 129 191 0.036 T 13-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria MADE_1013860 b0c5f84dcd9dfd47b383e7093b62dbbc 72 Gene3D G3DSA:3.30.420.10 3 59 1.1E-5 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1013860 b0c5f84dcd9dfd47b383e7093b62dbbc 72 SUPERFAMILY SSF53098 2 57 1.39E-9 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 Pfam PF04231 Endonuclease I 268 483 3.2E-42 T 13-10-2018 IPR007346 Endonuclease I GO:0004518 MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1320 1332 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1290 1302 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 Gene3D G3DSA:1.10.1330.10 1286 1344 1.8E-5 T 13-10-2018 MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 SUPERFAMILY SSF54060 263 483 2.59E-50 T 13-10-2018 MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 Pfam PF00932 Lamin Tail Domain 533 643 8.0E-13 T 13-10-2018 IPR001322 Lamin tail domain MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 979 1273 9.2E-11 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 SUPERFAMILY SSF63446 1285 1339 2.49E-7 T 13-10-2018 IPR036439 Dockerin domain superfamily GO:0000272 MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 SUPERFAMILY SSF56219 977 1281 4.58E-35 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1011800 b5abeed0c98bdacc8f6d61564da1b247 1346 Gene3D G3DSA:3.60.10.10 976 1280 5.0E-38 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1011825 788724a60281b985a06cce8693bcd7a3 384 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 357 3.6E-90 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MADE_1011825 788724a60281b985a06cce8693bcd7a3 384 Gene3D G3DSA:3.40.50.1970 1 181 8.7E-50 T 13-10-2018 MADE_1011825 788724a60281b985a06cce8693bcd7a3 384 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 261 281 - T 13-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 MADE_1011825 788724a60281b985a06cce8693bcd7a3 384 SUPERFAMILY SSF56796 2 363 8.37E-106 T 13-10-2018 MADE_1011825 788724a60281b985a06cce8693bcd7a3 384 Gene3D G3DSA:1.20.1090.10 182 383 2.4E-45 T 13-10-2018 MADE_1001510 780684a8f9a12f65a811c25937e13b07 128 Pfam PF03965 Penicillinase repressor 3 118 2.2E-20 T 13-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 MADE_1001510 780684a8f9a12f65a811c25937e13b07 128 SUPERFAMILY SSF46785 1 120 2.17E-20 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1001510 780684a8f9a12f65a811c25937e13b07 128 Gene3D G3DSA:1.10.10.10 1 66 2.8E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1007230 d18b749e7a655ac1d6f686964e96d197 495 Pfam PF08443 RimK-like ATP-grasp domain 297 466 2.2E-9 T 13-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 MADE_1007230 d18b749e7a655ac1d6f686964e96d197 495 Gene3D G3DSA:3.30.470.20 373 490 4.7E-20 T 13-10-2018 MADE_1007230 d18b749e7a655ac1d6f686964e96d197 495 SUPERFAMILY SSF56059 281 488 7.46E-40 T 13-10-2018 MADE_1007230 d18b749e7a655ac1d6f686964e96d197 495 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 25 163 1.6E-30 T 13-10-2018 IPR025839 RimK-like ATPgrasp N-terminal domain MADE_1007230 d18b749e7a655ac1d6f686964e96d197 495 Gene3D G3DSA:3.40.50.20 218 304 2.3E-5 T 13-10-2018 MADE_1007230 d18b749e7a655ac1d6f686964e96d197 495 Gene3D G3DSA:3.30.1490.20 306 372 1.5E-8 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 MADE_1007915 b42b887a858753aaa2135e701692fc4f 435 SUPERFAMILY SSF51556 65 368 4.4E-92 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1007915 b42b887a858753aaa2135e701692fc4f 435 Gene3D G3DSA:2.30.40.10 5 419 6.3E-163 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1007915 b42b887a858753aaa2135e701692fc4f 435 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 23 421 7.6E-161 T 13-10-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 MADE_1007915 b42b887a858753aaa2135e701692fc4f 435 Pfam PF01979 Amidohydrolase family 63 422 2.0E-59 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_1007915 b42b887a858753aaa2135e701692fc4f 435 SUPERFAMILY SSF51338 23 80 1.57E-12 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1007915 b42b887a858753aaa2135e701692fc4f 435 Gene3D G3DSA:3.20.20.140 66 383 6.3E-163 T 13-10-2018 MADE_1014120 5e7d5d1bc6be0787d87dfa6db9a4b63a 341 SUPERFAMILY SSF56176 6 219 2.45E-52 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_1014120 5e7d5d1bc6be0787d87dfa6db9a4b63a 341 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 22 219 4.8E-41 T 13-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 MADE_1014120 5e7d5d1bc6be0787d87dfa6db9a4b63a 341 SUPERFAMILY SSF55447 224 323 5.76E-23 T 13-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily MADE_1014120 5e7d5d1bc6be0787d87dfa6db9a4b63a 341 Gene3D G3DSA:3.30.465.10 1 221 1.9E-69 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1014120 5e7d5d1bc6be0787d87dfa6db9a4b63a 341 SMART SM01092 225 323 6.9E-21 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MADE_1014120 5e7d5d1bc6be0787d87dfa6db9a4b63a 341 Gene3D G3DSA:3.30.390.50 222 326 4.6E-20 T 13-10-2018 MADE_1014120 5e7d5d1bc6be0787d87dfa6db9a4b63a 341 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 321 5.0E-15 T 13-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal MADE_000001021435 db77f2b65b37f7632b9218de8e2037e9 302 Gene3D G3DSA:3.40.630.10 1 302 2.0E-110 T 13-10-2018 MADE_000001021435 db77f2b65b37f7632b9218de8e2037e9 302 SUPERFAMILY SSF53187 35 289 1.12E-33 T 13-10-2018 MADE_000001021435 db77f2b65b37f7632b9218de8e2037e9 302 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 78 176 1.1E-6 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MADE_1004660 2f52119c9de6347359c77b4966858f51 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 6 193 2.3E-63 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MADE_1004660 2f52119c9de6347359c77b4966858f51 200 Gene3D G3DSA:3.90.950.10 1 199 1.1E-76 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_1004660 2f52119c9de6347359c77b4966858f51 200 Hamap MF_01405 dITP/XTP pyrophosphatase. 5 197 48.772 T 13-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 MADE_1004660 2f52119c9de6347359c77b4966858f51 200 Pfam PF01725 Ham1 family 7 192 6.3E-57 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 MADE_1004660 2f52119c9de6347359c77b4966858f51 200 SUPERFAMILY SSF52972 5 195 8.63E-71 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_1006045 f6cc25f35052e11b14f5a1427bea7a90 196 Pfam PF06080 Protein of unknown function (DUF938) 5 195 8.9E-53 T 13-10-2018 IPR010342 Protein of unknown function DUF938 MADE_1006045 f6cc25f35052e11b14f5a1427bea7a90 196 Gene3D G3DSA:3.40.50.150 2 194 3.5E-13 T 13-10-2018 MADE_1006045 f6cc25f35052e11b14f5a1427bea7a90 196 SUPERFAMILY SSF53335 10 181 4.02E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1006795 a229dbce4d4ba1ce65b00e204286e31c 318 Gene3D G3DSA:1.10.8.300 199 315 1.3E-34 T 13-10-2018 MADE_1006795 a229dbce4d4ba1ce65b00e204286e31c 318 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 36 166 2.9E-62 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 MADE_1006795 a229dbce4d4ba1ce65b00e204286e31c 318 SUPERFAMILY SSF52540 6 290 4.44E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006795 a229dbce4d4ba1ce65b00e204286e31c 318 PIRSF PIRSF002849 1 318 4.2E-126 T 13-10-2018 MADE_1006795 a229dbce4d4ba1ce65b00e204286e31c 318 Gene3D G3DSA:3.40.50.300 17 183 1.2E-46 T 13-10-2018 MADE_1012410 b7e4eb514e778d2d6453dc23574b2f09 296 SUPERFAMILY SSF48576 1 275 7.44E-81 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily MADE_1012410 b7e4eb514e778d2d6453dc23574b2f09 296 Pfam PF00348 Polyprenyl synthetase 31 268 1.0E-54 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 MADE_1012410 b7e4eb514e778d2d6453dc23574b2f09 296 Gene3D G3DSA:1.10.600.10 2 296 5.7E-88 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily MADE_1012410 b7e4eb514e778d2d6453dc23574b2f09 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site MADE_1012410 b7e4eb514e778d2d6453dc23574b2f09 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site MADE_1004135 aa7ae7bc01e2bf13ea6c0bf6800e4c00 142 PIRSF PIRSF002181 1 142 5.1E-53 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MADE_1004135 aa7ae7bc01e2bf13ea6c0bf6800e4c00 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 29.173 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MADE_1004135 aa7ae7bc01e2bf13ea6c0bf6800e4c00 142 SUPERFAMILY SSF52161 1 140 4.97E-62 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1004135 aa7ae7bc01e2bf13ea6c0bf6800e4c00 142 Gene3D G3DSA:3.90.1180.10 1 142 3.6E-66 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 MADE_1004135 aa7ae7bc01e2bf13ea6c0bf6800e4c00 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 1.1E-66 T 13-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1004135 aa7ae7bc01e2bf13ea6c0bf6800e4c00 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 13-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 MADE_1004135 aa7ae7bc01e2bf13ea6c0bf6800e4c00 142 Pfam PF00572 Ribosomal protein L13 15 138 4.4E-59 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 13-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 Pfam PF00366 Ribosomal protein S17 11 77 1.0E-33 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 SUPERFAMILY SSF50249 7 84 1.07E-33 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 77 2.0E-30 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 4 81 24.693 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 Gene3D G3DSA:2.40.50.140 2 84 6.0E-37 T 13-10-2018 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 3.2E-13 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 3.2E-13 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 3.2E-13 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1002305 3c79260b051eadf4842bd467b7c9e71d 85 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 77 3.7E-37 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 Gene3D G3DSA:1.10.3860.10 3 416 1.5E-116 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 SUPERFAMILY SSF118215 13 401 2.48E-108 T 13-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 Pfam PF00375 Sodium:dicarboxylate symporter family 13 401 4.9E-117 T 13-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 356 376 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 145 167 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 228 247 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 5.2E-55 T 13-10-2018 MADE_1007775 e481b5c57ba4871843640b83022a43d5 417 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 5.2E-55 T 13-10-2018 MADE_1008640 540b4d7ba9e69375bd2cec434b18c5de 151 Gene3D G3DSA:3.40.630.30 1 149 6.6E-46 T 13-10-2018 MADE_1008640 540b4d7ba9e69375bd2cec434b18c5de 151 SUPERFAMILY SSF55729 1 148 1.11E-36 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1008640 540b4d7ba9e69375bd2cec434b18c5de 151 Pfam PF13673 Acetyltransferase (GNAT) domain 37 148 1.5E-19 T 13-10-2018 IPR000182 GNAT domain MADE_1003725 291a7bf698fe5e8629304c3c59c408f9 469 SUPERFAMILY SSF53850 46 310 2.93E-17 T 13-10-2018 MADE_1003725 291a7bf698fe5e8629304c3c59c408f9 469 Pfam PF13379 NMT1-like family 44 323 1.4E-104 T 13-10-2018 MADE_1003725 291a7bf698fe5e8629304c3c59c408f9 469 Gene3D G3DSA:3.40.190.10 135 452 4.2E-140 T 13-10-2018 MADE_1003725 291a7bf698fe5e8629304c3c59c408f9 469 Gene3D G3DSA:3.40.190.10 50 447 4.2E-140 T 13-10-2018 MADE_1013035 e7490d04e341b1a13956bf6453d512f9 450 Pfam PF07143 CrtC N-terminal lipocalin domain 98 314 6.1E-46 T 13-10-2018 IPR010791 AttH domain MADE_1013035 e7490d04e341b1a13956bf6453d512f9 450 Gene3D G3DSA:2.40.370.10 318 450 1.3E-31 T 13-10-2018 IPR023374 AttH-like domain superfamily MADE_1013035 e7490d04e341b1a13956bf6453d512f9 450 Pfam PF17186 Lipocalin-like domain 319 450 1.0E-37 T 13-10-2018 MADE_1013035 e7490d04e341b1a13956bf6453d512f9 450 Gene3D G3DSA:2.40.370.10 85 210 3.9E-31 T 13-10-2018 IPR023374 AttH-like domain superfamily MADE_1013035 e7490d04e341b1a13956bf6453d512f9 450 Gene3D G3DSA:2.40.370.10 211 316 7.4E-25 T 13-10-2018 IPR023374 AttH-like domain superfamily MADE_1013035 e7490d04e341b1a13956bf6453d512f9 450 SUPERFAMILY SSF159245 74 450 3.79E-89 T 13-10-2018 MADE_1013505 98ab113cce76436a94d61b61c5394914 381 Gene3D G3DSA:2.40.50.100 300 380 6.0E-7 T 13-10-2018 MADE_1013505 98ab113cce76436a94d61b61c5394914 381 SMART SM00382 20 189 4.4E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1013505 98ab113cce76436a94d61b61c5394914 381 Pfam PF00005 ABC transporter 21 138 6.1E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1013505 98ab113cce76436a94d61b61c5394914 381 Gene3D G3DSA:3.40.50.300 8 210 1.4E-43 T 13-10-2018 MADE_1013505 98ab113cce76436a94d61b61c5394914 381 SUPERFAMILY SSF52540 20 201 1.41E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1013505 98ab113cce76436a94d61b61c5394914 381 ProSitePatterns PS00211 ABC transporters family signature. 112 126 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1020150 5d2e72b0584675511b013d88f8583313 416 SUPERFAMILY SSF103473 25 404 7.46E-46 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1020150 5d2e72b0584675511b013d88f8583313 416 Gene3D G3DSA:1.20.1720.10 25 405 6.3E-79 T 13-10-2018 MADE_1020150 5d2e72b0584675511b013d88f8583313 416 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 25 385 1.0E-60 T 13-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 MADE_1020150 5d2e72b0584675511b013d88f8583313 416 Pfam PF07690 Major Facilitator Superfamily 32 369 6.8E-30 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 PRINTS PR00147 DNA photolyase signature 357 373 1.4E-7 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 PRINTS PR00147 DNA photolyase signature 377 395 1.4E-7 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 SUPERFAMILY SSF48173 223 509 1.31E-75 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 Gene3D G3DSA:3.40.50.620 8 134 4.5E-19 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 SUPERFAMILY SSF52425 10 185 2.22E-29 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 357 369 - T 13-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 Gene3D G3DSA:1.25.40.80 168 319 5.5E-19 T 13-10-2018 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 Gene3D G3DSA:1.10.579.10 324 524 3.1E-56 T 13-10-2018 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 Pfam PF03441 FAD binding domain of DNA photolyase 307 503 9.4E-55 T 13-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 MADE_1010195 bd6e58cb657f2c51a2c3e68c34cbf8ac 543 Pfam PF00875 DNA photolyase 12 132 1.8E-13 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 MADE_1015765 c7b1b75303503ad8220271f78762f423 187 Pfam PF03703 Bacterial PH domain 103 178 8.0E-15 T 13-10-2018 IPR005182 Domain of unknown function DUF304 MADE_1001220 2063e33ed5e5d01fc272ecd6a71f389c 215 Pfam PF04612 Type II secretion system (T2SS), protein M 5 79 1.6E-6 T 13-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 MADE_1016080 c4b27a4c5564ca7b9c8ce6941ae3143d 686 Pfam PF00593 TonB dependent receptor 240 685 2.4E-35 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1016080 c4b27a4c5564ca7b9c8ce6941ae3143d 686 Gene3D G3DSA:2.40.170.20 183 686 4.8E-44 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1016080 c4b27a4c5564ca7b9c8ce6941ae3143d 686 SUPERFAMILY SSF56935 25 686 7.02E-71 T 13-10-2018 MADE_1016080 c4b27a4c5564ca7b9c8ce6941ae3143d 686 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 158 1.0E-11 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1016080 c4b27a4c5564ca7b9c8ce6941ae3143d 686 Gene3D G3DSA:2.170.130.10 35 161 4.5E-9 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_000001022725 430ca73a1a629cb755133366abe0232d 72 SUPERFAMILY SSF56349 1 66 8.24E-11 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_000001022725 430ca73a1a629cb755133366abe0232d 72 Pfam PF00589 Phage integrase family 1 65 2.2E-6 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_000001022725 430ca73a1a629cb755133366abe0232d 72 Gene3D G3DSA:1.10.443.10 1 71 5.2E-8 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1016295 54b53084a46c8bb9c8df80efc8acb791 720 Gene3D G3DSA:2.170.130.10 49 179 7.3E-29 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1016295 54b53084a46c8bb9c8df80efc8acb791 720 Gene3D G3DSA:2.40.170.20 180 720 4.3E-104 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1016295 54b53084a46c8bb9c8df80efc8acb791 720 SUPERFAMILY SSF56935 41 720 4.19E-120 T 13-10-2018 MADE_1016295 54b53084a46c8bb9c8df80efc8acb791 720 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 68 720 1.0E-91 T 13-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 MADE_1016295 54b53084a46c8bb9c8df80efc8acb791 720 Pfam PF00593 TonB dependent receptor 241 719 3.3E-50 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1016295 54b53084a46c8bb9c8df80efc8acb791 720 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 168 1.1E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1007435 773570e38a23cfed9379383fb4ee862f 118 SUPERFAMILY SSF82771 23 94 3.92E-8 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MADE_1007435 773570e38a23cfed9379383fb4ee862f 118 Gene3D G3DSA:3.40.1440.10 18 116 5.3E-23 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 MADE_1007435 773570e38a23cfed9379383fb4ee862f 118 Pfam PF01541 GIY-YIG catalytic domain 23 95 2.8E-13 T 13-10-2018 IPR000305 GIY-YIG endonuclease MADE_1012340 aaf1aa8214435b4976b66e455d677478 251 Gene3D G3DSA:3.60.140.10 6 251 2.0E-77 T 13-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily MADE_1012340 aaf1aa8214435b4976b66e455d677478 251 SUPERFAMILY SSF64438 15 249 5.31E-74 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic MADE_1012340 aaf1aa8214435b4976b66e455d677478 251 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 43 247 4.9E-55 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase MADE_1012340 aaf1aa8214435b4976b66e455d677478 251 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 32 248 1.2E-65 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase MADE_1005630 dcfe20278d041bfc18186b72c3090480 267 Pfam PF04116 Fatty acid hydroxylase superfamily 89 225 6.8E-28 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 SUPERFAMILY SSF52402 208 482 3.67E-73 T 13-10-2018 MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 SUPERFAMILY SSF56235 1 196 1.12E-57 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 Pfam PF00733 Asparagine synthase 211 366 2.8E-55 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 Pfam PF13537 Glutamine amidotransferase domain 48 166 1.8E-39 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 Gene3D G3DSA:3.40.50.620 194 516 2.5E-113 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 PIRSF PIRSF001589 361 511 5.0E-26 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 PIRSF PIRSF001589 1 367 4.8E-108 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 373 8.0E-118 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 MADE_1006695 b47a06ca1b6aaa1598cebde580aaf709 556 Gene3D G3DSA:3.60.20.10 2 193 1.9E-70 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal MADE_1012885 fb8db375b6a72e087b5cbde5708f73e7 118 Pfam PF01521 Iron-sulphur cluster biosynthesis 13 113 5.4E-16 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 MADE_1012885 fb8db375b6a72e087b5cbde5708f73e7 118 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 13 117 3.0E-24 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 MADE_1012885 fb8db375b6a72e087b5cbde5708f73e7 118 Gene3D G3DSA:2.60.300.12 12 117 1.2E-25 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MADE_1012885 fb8db375b6a72e087b5cbde5708f73e7 118 SUPERFAMILY SSF89360 12 105 1.12E-18 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 MADE_1014470 f1fbcfc61ffc13982c701c0f6b90c3fd 291 SUPERFAMILY SSF103481 197 290 5.89E-5 T 13-10-2018 MADE_1014470 f1fbcfc61ffc13982c701c0f6b90c3fd 291 SUPERFAMILY SSF103481 37 143 2.88E-5 T 13-10-2018 MADE_1008560 234580332e129c99b6ee4e42f5181749 156 Pfam PF00075 RNase H 4 142 5.1E-53 T 13-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 MADE_1008560 234580332e129c99b6ee4e42f5181749 156 Gene3D G3DSA:3.30.420.10 2 152 4.0E-61 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1008560 234580332e129c99b6ee4e42f5181749 156 SUPERFAMILY SSF53098 4 143 3.04E-59 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1008560 234580332e129c99b6ee4e42f5181749 156 Hamap MF_00042 Ribonuclease H [rnhA]. 3 151 36.327 T 13-10-2018 IPR022892 Ribonuclease HI GO:0004523 MADE_1006360 a050087241d7b29f9ea58eb5f285b8f9 311 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 90 2.1E-6 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1006360 a050087241d7b29f9ea58eb5f285b8f9 311 SMART SM00829 10 308 7.4E-6 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1006360 a050087241d7b29f9ea58eb5f285b8f9 311 Gene3D G3DSA:3.40.50.720 122 246 1.3E-103 T 13-10-2018 MADE_1006360 a050087241d7b29f9ea58eb5f285b8f9 311 SUPERFAMILY SSF51735 114 263 8.96E-16 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1006360 a050087241d7b29f9ea58eb5f285b8f9 311 Gene3D G3DSA:3.90.180.10 6 292 1.3E-103 T 13-10-2018 MADE_1006360 a050087241d7b29f9ea58eb5f285b8f9 311 SUPERFAMILY SSF50129 6 148 6.85E-30 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1015075 29c3f15ec58ea0a9d0ae3f0903d04eec 125 SMART SM00448 2 115 1.2E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015075 29c3f15ec58ea0a9d0ae3f0903d04eec 125 Pfam PF00072 Response regulator receiver domain 4 115 5.8E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1015075 29c3f15ec58ea0a9d0ae3f0903d04eec 125 SUPERFAMILY SSF52172 1 120 1.04E-33 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1015075 29c3f15ec58ea0a9d0ae3f0903d04eec 125 Gene3D G3DSA:3.40.50.12740 2 125 5.5E-35 T 13-10-2018 MADE_1012930 fd18bc6e79c5764c4a4e84dd053a31f0 261 Gene3D G3DSA:1.10.8.590 165 246 3.9E-28 T 13-10-2018 MADE_1012930 fd18bc6e79c5764c4a4e84dd053a31f0 261 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 236 1.1E-84 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 MADE_1012930 fd18bc6e79c5764c4a4e84dd053a31f0 261 Pfam PF00588 SpoU rRNA Methylase family 5 154 5.5E-33 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MADE_1012930 fd18bc6e79c5764c4a4e84dd053a31f0 261 Gene3D G3DSA:3.40.1280.10 1 164 6.2E-64 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_1012930 fd18bc6e79c5764c4a4e84dd053a31f0 261 SUPERFAMILY SSF75217 4 166 2.22E-36 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_1012930 fd18bc6e79c5764c4a4e84dd053a31f0 261 PIRSF PIRSF004808 1 240 7.4E-75 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 MADE_1004750 077fbd1c477f80e99c2d5f3cc7689a0b 105 Gene3D G3DSA:3.40.1690.10 7 90 7.1E-20 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MADE_1004750 077fbd1c477f80e99c2d5f3cc7689a0b 105 Pfam PF01312 FlhB HrpN YscU SpaS Family 10 82 1.2E-14 T 13-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 MADE_1004750 077fbd1c477f80e99c2d5f3cc7689a0b 105 SUPERFAMILY SSF160544 8 86 2.22E-18 T 13-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal MADE_1020360 1ef66af3a83704957dc99d29b99552ed 80 Gene3D G3DSA:1.10.238.160 22 73 3.8E-6 T 13-10-2018 MADE_1020360 1ef66af3a83704957dc99d29b99552ed 80 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 19 68 1.4E-25 T 13-10-2018 IPR010260 DNA-binding transcriptional activator AlpA MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 SUPERFAMILY SSF52540 388 568 2.35E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 Pfam PF00664 ABC transporter transmembrane region 41 291 2.5E-18 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 SMART SM00382 398 566 8.2E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 Gene3D G3DSA:3.40.50.300 373 584 4.7E-41 T 13-10-2018 MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 SUPERFAMILY SSF90123 32 333 3.4E-26 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 Pfam PF00005 ABC transporter 393 520 2.5E-16 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1019060 2e173d49283171ed4887c6e4c4c1ff74 584 Gene3D G3DSA:1.20.1560.10 132 336 7.3E-20 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 MADE_1019070 3b12e5fb6305d42a5a2d607427265248 378 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 362 3.2E-103 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MADE_1019070 3b12e5fb6305d42a5a2d607427265248 378 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 375 3.0E-157 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MADE_1019070 3b12e5fb6305d42a5a2d607427265248 378 PIRSF PIRSF000267 2 377 3.7E-124 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 MADE_1006035 5f30036510eb5fa4348df202242958a0 355 SUPERFAMILY SSF82282 12 354 3.14E-106 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MADE_1006035 5f30036510eb5fa4348df202242958a0 355 PIRSF PIRSF037505 58 256 7.6E-7 T 13-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 MADE_1006035 5f30036510eb5fa4348df202242958a0 355 PIRSF PIRSF037505 291 351 0.015 T 13-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 MADE_1006035 5f30036510eb5fa4348df202242958a0 355 Gene3D G3DSA:3.20.20.330 6 344 9.4E-130 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MADE_1006035 5f30036510eb5fa4348df202242958a0 355 Pfam PF02574 Homocysteine S-methyltransferase 22 330 3.3E-83 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MADE_000001022585 ac5bc8862e8bbffb433097c3be7a4c2b 267 Pfam PF04338 Protein of unknown function, DUF481 53 266 7.8E-48 T 13-10-2018 IPR007433 Protein of unknown function DUF481 MADE_1006310 1d5f4f539953b3724c9aa0d549d9154c 304 SUPERFAMILY SSF56112 62 271 3.63E-24 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1006310 1d5f4f539953b3724c9aa0d549d9154c 304 Pfam PF01636 Phosphotransferase enzyme family 116 265 2.0E-13 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase MADE_1006310 1d5f4f539953b3724c9aa0d549d9154c 304 Gene3D G3DSA:3.90.1200.10 136 302 2.7E-19 T 13-10-2018 MADE_1000695 7478d6a4196b83bb5087bb56b3060fd5 378 Gene3D G3DSA:3.20.20.70 10 369 1.1E-103 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1000695 7478d6a4196b83bb5087bb56b3060fd5 378 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 5 371 2.2E-154 T 13-10-2018 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 MADE_1000695 7478d6a4196b83bb5087bb56b3060fd5 378 Pfam PF04055 Radical SAM superfamily 81 226 2.4E-11 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 MADE_1000695 7478d6a4196b83bb5087bb56b3060fd5 378 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 257 364 1.5E-23 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MADE_1000695 7478d6a4196b83bb5087bb56b3060fd5 378 SMART SM00876 256 365 5.9E-27 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 MADE_1000695 7478d6a4196b83bb5087bb56b3060fd5 378 SUPERFAMILY SSF102114 36 363 6.28E-50 T 13-10-2018 MADE_1007665 1b4ae1d39801438ce7110646a6d1bc27 123 PIRSF PIRSF005610 1 119 1.7E-23 T 13-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MADE_1007665 1b4ae1d39801438ce7110646a6d1bc27 123 Pfam PF04247 Invasion gene expression up-regulator, SirB 2 121 2.0E-40 T 13-10-2018 IPR007360 Invasion gene expression up-regulator, SirB MADE_1009850 7becbdecfb05c093a67e55853340aca8 234 SMART SM00387 124 234 4.9E-4 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1009850 7becbdecfb05c093a67e55853340aca8 234 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 125 234 3.2E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase MADE_1009850 7becbdecfb05c093a67e55853340aca8 234 SUPERFAMILY SSF55874 69 234 1.31E-20 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1009850 7becbdecfb05c093a67e55853340aca8 234 Gene3D G3DSA:3.30.565.10 87 234 5.4E-21 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily MADE_1009850 7becbdecfb05c093a67e55853340aca8 234 PRINTS PR00344 Bacterial sensor protein C-terminal signature 191 209 1.0E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1009850 7becbdecfb05c093a67e55853340aca8 234 PRINTS PR00344 Bacterial sensor protein C-terminal signature 160 174 1.0E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1009850 7becbdecfb05c093a67e55853340aca8 234 PRINTS PR00344 Bacterial sensor protein C-terminal signature 221 234 1.0E-5 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 MADE_1004145 04d111518c529067a5ef4e5124066e3c 244 Pfam PF02167 Cytochrome C1 family 31 243 1.0E-17 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 MADE_1004145 04d111518c529067a5ef4e5124066e3c 244 Gene3D G3DSA:1.10.760.10 24 209 6.1E-20 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1004145 04d111518c529067a5ef4e5124066e3c 244 SUPERFAMILY SSF46626 16 208 9.02E-49 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 Hamap MF_00163 Peptide deformylase [def]. 2 162 30.969 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 3.3E-58 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 Pfam PF01327 Polypeptide deformylase 5 152 3.6E-51 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 Gene3D G3DSA:3.90.45.10 1 167 3.9E-65 T 13-10-2018 IPR036821 Peptide deformylase superfamily MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 PIRSF PIRSF004749 1 168 2.3E-57 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 PRINTS PR01576 Peptide deformylase signature 33 62 7.1E-38 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 PRINTS PR01576 Peptide deformylase signature 120 149 7.1E-38 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 PRINTS PR01576 Peptide deformylase signature 101 119 7.1E-38 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 PRINTS PR01576 Peptide deformylase signature 89 100 7.1E-38 T 13-10-2018 IPR023635 Peptide deformylase MADE_1000105 2118122a3e328ac22c53ace6cd7d676b 169 SUPERFAMILY SSF56420 2 164 4.06E-62 T 13-10-2018 IPR036821 Peptide deformylase superfamily MADE_000001021050 50eb49369a7b2ea8eed64811e85d468c 83 SUPERFAMILY SSF54565 1 76 2.49E-27 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021050 50eb49369a7b2ea8eed64811e85d468c 83 Gene3D G3DSA:3.30.1320.10 1 82 9.8E-30 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021050 50eb49369a7b2ea8eed64811e85d468c 83 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.955 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021050 50eb49369a7b2ea8eed64811e85d468c 83 Pfam PF00886 Ribosomal protein S16 8 68 3.4E-23 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021050 50eb49369a7b2ea8eed64811e85d468c 83 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 6.7E-27 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1000810 e46b2e211109765c6e66d24ad2c65936 507 SUPERFAMILY SSF161098 4 243 1.78E-39 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1000810 e46b2e211109765c6e66d24ad2c65936 507 SUPERFAMILY SSF161098 261 490 9.35E-35 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1000810 e46b2e211109765c6e66d24ad2c65936 507 Gene3D G3DSA:1.10.3720.10 261 498 2.1E-34 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1000810 e46b2e211109765c6e66d24ad2c65936 507 Gene3D G3DSA:1.10.3720.10 7 248 3.9E-45 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1000810 e46b2e211109765c6e66d24ad2c65936 507 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 62 238 4.3E-13 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1000810 e46b2e211109765c6e66d24ad2c65936 507 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 317 489 1.6E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1015910 86186fd70dfde7f2dee98e84960951ca 86 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 84 18.839 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MADE_1015910 86186fd70dfde7f2dee98e84960951ca 86 Pfam PF03776 Septum formation topological specificity factor MinE 15 82 6.7E-26 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MADE_1015910 86186fd70dfde7f2dee98e84960951ca 86 SUPERFAMILY SSF55229 34 84 5.36E-16 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 MADE_1015910 86186fd70dfde7f2dee98e84960951ca 86 Gene3D G3DSA:3.30.1070.10 1 83 1.6E-30 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 MADE_1015910 86186fd70dfde7f2dee98e84960951ca 86 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 9.9E-29 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 MADE_1015050 9692a38d70d32c8cbaeebe87a04a9219 429 SUPERFAMILY SSF58104 99 344 1.44E-34 T 13-10-2018 MADE_1015050 9692a38d70d32c8cbaeebe87a04a9219 429 SMART SM00283 103 371 7.8E-5 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1015050 9692a38d70d32c8cbaeebe87a04a9219 429 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 190 343 5.6E-27 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1015050 9692a38d70d32c8cbaeebe87a04a9219 429 Gene3D G3DSA:1.10.287.950 84 387 9.5E-38 T 13-10-2018 MADE_1012395 b587e503e4b2a87f96636a0ac9fae8d6 309 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 57 1.7E-18 T 13-10-2018 IPR025713 Motility protein B, N-terminal domain MADE_1012395 b587e503e4b2a87f96636a0ac9fae8d6 309 Gene3D G3DSA:3.30.1330.60 146 295 1.1E-42 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1012395 b587e503e4b2a87f96636a0ac9fae8d6 309 SUPERFAMILY SSF103088 175 293 1.29E-26 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1012395 b587e503e4b2a87f96636a0ac9fae8d6 309 Pfam PF00691 OmpA family 188 287 5.0E-14 T 13-10-2018 IPR006665 OmpA-like domain MADE_000001022830 9c871335dade613fcaebfccbea1ec58b 213 SMART SM00849 12 192 3.1E-33 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_000001022830 9c871335dade613fcaebfccbea1ec58b 213 Gene3D G3DSA:3.60.15.10 1 210 2.6E-75 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_000001022830 9c871335dade613fcaebfccbea1ec58b 213 Pfam PF00753 Metallo-beta-lactamase superfamily 10 192 4.6E-25 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_000001022830 9c871335dade613fcaebfccbea1ec58b 213 SUPERFAMILY SSF56281 3 208 6.09E-53 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1018035 fb20e5d763e3c9cbda0d3b2446edade6 564 Gene3D G3DSA:2.60.40.380 35 137 2.3E-34 T 13-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 MADE_1018035 fb20e5d763e3c9cbda0d3b2446edade6 564 Pfam PF09423 PhoD-like phosphatase 146 541 7.8E-117 T 13-10-2018 IPR018946 Alkaline phosphatase D-related MADE_1018035 fb20e5d763e3c9cbda0d3b2446edade6 564 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 44 135 2.4E-31 T 13-10-2018 IPR032093 Phospholipase D, N-terminal MADE_1018035 fb20e5d763e3c9cbda0d3b2446edade6 564 SUPERFAMILY SSF56300 138 545 3.42E-31 T 13-10-2018 MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 13-10-2018 IPR019844 Cold-shock conserved site MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 Pfam PF00313 'Cold-shock' DNA-binding domain 4 68 2.0E-30 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 PRINTS PR00050 Cold shock protein signature 42 60 6.3E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 PRINTS PR00050 Cold shock protein signature 27 36 6.3E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 PRINTS PR00050 Cold shock protein signature 6 21 6.3E-19 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 PIRSF PIRSF002599 1 69 4.5E-25 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 SMART SM00357 5 69 1.4E-30 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 SUPERFAMILY SSF50249 3 68 2.03E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1018140 a48581cad7cf70ce4c7ca75e1e6e7deb 69 Gene3D G3DSA:2.40.50.140 1 69 3.1E-31 T 13-10-2018 MADE_000001023550 e23e81335f255eb914402f5a1f2288c2 82 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 3.5E-30 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MADE_000001023550 e23e81335f255eb914402f5a1f2288c2 82 Gene3D G3DSA:2.30.30.100 1 81 8.6E-34 T 13-10-2018 MADE_000001023550 e23e81335f255eb914402f5a1f2288c2 82 Pfam PF17209 Hfq protein 7 68 2.3E-31 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MADE_000001023550 e23e81335f255eb914402f5a1f2288c2 82 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.752 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 MADE_000001023550 e23e81335f255eb914402f5a1f2288c2 82 SUPERFAMILY SSF50182 7 69 1.85E-24 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1006450 ec3d385715b1cf51b84b9dc6ccf5bc9e 387 Pfam PF00487 Fatty acid desaturase 97 367 3.3E-27 T 13-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MADE_1009650 1b917263560b25eb61017bb88bead00a 376 SUPERFAMILY SSF52096 18 371 3.38E-63 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_1009650 1b917263560b25eb61017bb88bead00a 376 Pfam PF16113 Enoyl-CoA hydratase/isomerase 22 362 9.1E-119 T 13-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 MADE_1009650 1b917263560b25eb61017bb88bead00a 376 Gene3D G3DSA:3.90.226.10 7 376 1.2E-128 T 13-10-2018 MADE_1013545 8ce6c40fa34339fb5c13094207759fc0 372 Gene3D G3DSA:2.40.50.100 294 364 4.3E-131 T 13-10-2018 MADE_1013545 8ce6c40fa34339fb5c13094207759fc0 372 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 33 366 6.3E-52 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 MADE_1013545 8ce6c40fa34339fb5c13094207759fc0 372 Gene3D G3DSA:3.40.630.10 14 293 4.3E-131 T 13-10-2018 MADE_1013545 8ce6c40fa34339fb5c13094207759fc0 372 SUPERFAMILY SSF53187 13 358 1.59E-37 T 13-10-2018 MADE_1006855 92cc547161e53cc35e0624154f194201 224 SMART SM00862 145 220 3.2E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1006855 92cc547161e53cc35e0624154f194201 224 Gene3D G3DSA:1.10.10.10 123 223 1.2E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1006855 92cc547161e53cc35e0624154f194201 224 Gene3D G3DSA:3.40.50.2300 1 122 5.7E-40 T 13-10-2018 MADE_1006855 92cc547161e53cc35e0624154f194201 224 Pfam PF00072 Response regulator receiver domain 3 111 1.6E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1006855 92cc547161e53cc35e0624154f194201 224 SMART SM00448 1 112 7.3E-39 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1006855 92cc547161e53cc35e0624154f194201 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 2.7E-22 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1006855 92cc547161e53cc35e0624154f194201 224 SUPERFAMILY SSF52172 1 175 2.78E-39 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1000805 4c470dfe7be7b0fb064a6ab91b4b14f4 344 Pfam PF13343 Bacterial extracellular solute-binding protein 98 310 1.1E-10 T 13-10-2018 MADE_1000805 4c470dfe7be7b0fb064a6ab91b4b14f4 344 SUPERFAMILY SSF53850 44 332 4.24E-45 T 13-10-2018 MADE_1000805 4c470dfe7be7b0fb064a6ab91b4b14f4 344 Gene3D G3DSA:3.40.190.10 142 325 1.3E-68 T 13-10-2018 MADE_1000805 4c470dfe7be7b0fb064a6ab91b4b14f4 344 PIRSF PIRSF002825 1 344 3.7E-83 T 13-10-2018 IPR026045 Ferric binding protein MADE_1000805 4c470dfe7be7b0fb064a6ab91b4b14f4 344 Gene3D G3DSA:3.40.190.10 45 313 1.3E-68 T 13-10-2018 MADE_1018965 b0e21faba167bb4e5504b8fd120f0c45 254 SMART SM00382 43 233 2.3E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1018965 b0e21faba167bb4e5504b8fd120f0c45 254 Gene3D G3DSA:3.40.50.300 14 253 1.0E-60 T 13-10-2018 MADE_1018965 b0e21faba167bb4e5504b8fd120f0c45 254 Pfam PF00005 ABC transporter 38 186 1.0E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1018965 b0e21faba167bb4e5504b8fd120f0c45 254 SUPERFAMILY SSF52540 10 228 4.41E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006720 3956d39880863301b514c03aeb8c0a71 574 SUPERFAMILY SSF116726 292 358 3.01E-14 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1006720 3956d39880863301b514c03aeb8c0a71 574 Pfam PF02080 TrkA-C domain 294 354 1.2E-8 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MADE_1006720 3956d39880863301b514c03aeb8c0a71 574 Pfam PF02080 TrkA-C domain 208 275 3.6E-10 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 MADE_1006720 3956d39880863301b514c03aeb8c0a71 574 SUPERFAMILY SSF116726 204 283 1.57E-16 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1006720 3956d39880863301b514c03aeb8c0a71 574 Pfam PF03600 Citrate transporter 19 520 1.1E-31 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 MADE_1006720 3956d39880863301b514c03aeb8c0a71 574 Gene3D G3DSA:3.30.70.1450 204 280 6.8E-14 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_1006720 3956d39880863301b514c03aeb8c0a71 574 Gene3D G3DSA:3.30.70.1450 291 362 2.0E-12 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 MADE_000001022435 c3065a08303ccadd978d25630310e802 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 MADE_000001022435 c3065a08303ccadd978d25630310e802 488 Pfam PF00171 Aldehyde dehydrogenase family 18 477 9.2E-170 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_000001022435 c3065a08303ccadd978d25630310e802 488 Gene3D G3DSA:3.40.605.10 1 251 2.7E-89 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_000001022435 c3065a08303ccadd978d25630310e802 488 Gene3D G3DSA:3.40.309.10 252 486 6.3E-83 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_000001022435 c3065a08303ccadd978d25630310e802 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 MADE_000001022435 c3065a08303ccadd978d25630310e802 488 SUPERFAMILY SSF53720 3 483 4.06E-163 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1008980 c0536fda79dcf787152428432b559e51 863 Gene3D G3DSA:3.60.10.10 463 817 9.6E-26 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1008980 c0536fda79dcf787152428432b559e51 863 SUPERFAMILY SSF56219 455 822 6.19E-28 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1013090 761528ff13c26338a4f2c2fef43eb849 203 TIGRFAM TIGR04352 HprK_rel_A: HprK-related kinase A 1 201 3.7E-68 T 13-10-2018 IPR027600 HprK-related kinase A MADE_1013090 761528ff13c26338a4f2c2fef43eb849 203 SUPERFAMILY SSF53795 17 82 1.04E-10 T 13-10-2018 MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 SUPERFAMILY SSF52343 102 229 2.36E-33 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 Gene3D G3DSA:3.40.50.80 101 231 5.6E-28 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 Pfam PF00175 Oxidoreductase NAD-binding domain 107 210 2.6E-21 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 Gene3D G3DSA:2.40.30.10 2 98 7.0E-21 T 13-10-2018 MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 SUPERFAMILY SSF63380 4 97 9.68E-18 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 PRINTS PR00410 Phenol hydroxylase reductase family signature 131 140 9.8E-11 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 PRINTS PR00410 Phenol hydroxylase reductase family signature 47 54 9.8E-11 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 PRINTS PR00410 Phenol hydroxylase reductase family signature 31 43 9.8E-11 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MADE_1018080 e4a67d6ccadfbbe05078cffca35aa5cb 231 PRINTS PR00410 Phenol hydroxylase reductase family signature 106 125 9.8E-11 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 MADE_1002785 8468625876285a9e11d0d0b1ebea4d6d 130 Pfam PF04219 Protein of unknown function, DUF 19 105 2.1E-29 T 13-10-2018 IPR007335 Protein of unknown function DUF413 MADE_1003700 7ad18f21847596f52926b747e9bad390 123 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 16 121 4.1E-30 T 13-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MADE_1003700 7ad18f21847596f52926b747e9bad390 123 SUPERFAMILY SSF50022 15 122 8.94E-31 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MADE_1003700 7ad18f21847596f52926b747e9bad390 123 Pfam PF13806 Rieske-like [2Fe-2S] domain 16 121 2.7E-33 T 13-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 MADE_1003700 7ad18f21847596f52926b747e9bad390 123 Gene3D G3DSA:2.102.10.10 9 122 2.3E-30 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 MADE_1003660 ced6f219232b021976842874df6ba0d2 106 SUPERFAMILY SSF82657 4 88 5.1E-28 T 13-10-2018 IPR036065 BolA-like superfamily MADE_1003660 ced6f219232b021976842874df6ba0d2 106 Gene3D G3DSA:3.30.300.90 1 89 1.7E-31 T 13-10-2018 MADE_1003660 ced6f219232b021976842874df6ba0d2 106 Pfam PF01722 BolA-like protein 11 84 1.8E-28 T 13-10-2018 IPR002634 BolA protein MADE_1003660 ced6f219232b021976842874df6ba0d2 106 PIRSF PIRSF003113 1 100 1.5E-31 T 13-10-2018 IPR002634 BolA protein MADE_1006735 e43c900547b0de9bf224a6d2912e2612 198 Gene3D G3DSA:3.40.50.300 2 198 1.1E-80 T 13-10-2018 MADE_1006735 e43c900547b0de9bf224a6d2912e2612 198 Pfam PF01583 Adenylylsulphate kinase 27 177 4.3E-74 T 13-10-2018 MADE_1006735 e43c900547b0de9bf224a6d2912e2612 198 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 24 196 38.263 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MADE_1006735 e43c900547b0de9bf224a6d2912e2612 198 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 8 191 5.5E-82 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 MADE_1006735 e43c900547b0de9bf224a6d2912e2612 198 SUPERFAMILY SSF52540 24 195 7.44E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_000001022665 ba6428f93ecf8009b88c1bb95fae4402 506 SUPERFAMILY SSF56935 4 505 1.06E-26 T 13-10-2018 MADE_1018435 028749ace8d74ffa580421ff923d4a3d 165 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 6 136 9.2E-44 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1018435 028749ace8d74ffa580421ff923d4a3d 165 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 7 136 1.6E-37 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1018435 028749ace8d74ffa580421ff923d4a3d 165 SUPERFAMILY SSF55083 5 159 1.26E-51 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1018435 028749ace8d74ffa580421ff923d4a3d 165 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 91 102 - T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1018435 028749ace8d74ffa580421ff923d4a3d 165 Gene3D G3DSA:3.30.70.560 5 161 4.5E-56 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 SUPERFAMILY SSF51735 1 336 2.16E-90 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 Gene3D G3DSA:3.90.25.10 183 331 2.5E-97 T 13-10-2018 MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 265 3.0E-56 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 Gene3D G3DSA:3.40.50.720 4 319 2.5E-97 T 13-10-2018 MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 PRINTS PR01713 Nucleotide sugar epimerase signature 259 274 7.7E-29 T 13-10-2018 MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 PRINTS PR01713 Nucleotide sugar epimerase signature 298 315 7.7E-29 T 13-10-2018 MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 PRINTS PR01713 Nucleotide sugar epimerase signature 219 234 7.7E-29 T 13-10-2018 MADE_1013075 8b94d7a5a9d665150fe4e2a902709fc4 338 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 7.7E-29 T 13-10-2018 MADE_1007065 5a9e78b628235a0f0e0223e6a613e450 160 PRINTS PR00608 Class II cytochrome C signature 124 147 3.6E-7 T 13-10-2018 IPR015984 Cytochrome c prime, subgroup MADE_1007065 5a9e78b628235a0f0e0223e6a613e450 160 PRINTS PR00608 Class II cytochrome C signature 147 158 3.6E-7 T 13-10-2018 IPR015984 Cytochrome c prime, subgroup MADE_1007065 5a9e78b628235a0f0e0223e6a613e450 160 Pfam PF01322 Cytochrome C' 38 158 4.3E-31 T 13-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 MADE_1007065 5a9e78b628235a0f0e0223e6a613e450 160 PIRSF PIRSF000027 9 160 8.3E-33 T 13-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 MADE_1007065 5a9e78b628235a0f0e0223e6a613e450 160 SUPERFAMILY SSF47175 35 158 8.1E-33 T 13-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 MADE_1007065 5a9e78b628235a0f0e0223e6a613e450 160 Gene3D G3DSA:1.20.120.10 31 160 4.8E-34 T 13-10-2018 MADE_1013190 62aff62215ceb08a0472e0951906799d 375 Pfam PF13439 Glycosyltransferase Family 4 12 114 7.8E-7 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1013190 62aff62215ceb08a0472e0951906799d 375 Gene3D G3DSA:3.40.50.2000 1 171 1.5E-9 T 13-10-2018 MADE_1013190 62aff62215ceb08a0472e0951906799d 375 Gene3D G3DSA:3.40.50.2000 172 352 2.1E-30 T 13-10-2018 MADE_1013190 62aff62215ceb08a0472e0951906799d 375 Pfam PF00534 Glycosyl transferases group 1 184 346 3.7E-23 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1013190 62aff62215ceb08a0472e0951906799d 375 SUPERFAMILY SSF53756 3 366 2.69E-52 T 13-10-2018 MADE_1001715 b50c379eb82e2854340cad033a335ac1 136 SMART SM00422 1 69 4.4E-17 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1001715 b50c379eb82e2854340cad033a335ac1 136 SUPERFAMILY SSF46955 1 114 2.45E-27 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1001715 b50c379eb82e2854340cad033a335ac1 136 Gene3D G3DSA:1.10.1660.10 1 122 1.9E-28 T 13-10-2018 MADE_1001715 b50c379eb82e2854340cad033a335ac1 136 Pfam PF00376 MerR family regulatory protein 3 38 6.6E-7 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1001715 b50c379eb82e2854340cad033a335ac1 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.8E-6 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1001715 b50c379eb82e2854340cad033a335ac1 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.8E-6 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1001715 b50c379eb82e2854340cad033a335ac1 136 Pfam PF09278 MerR, DNA binding 43 105 2.2E-16 T 13-10-2018 IPR015358 Transcription regulator MerR, DNA binding MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 SUPERFAMILY SSF56176 268 471 4.49E-47 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 303 336 - T 13-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 Gene3D G3DSA:3.30.43.10 278 355 2.8E-18 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 Gene3D G3DSA:3.30.465.10 369 692 7.3E-70 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 8.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 8.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 8.9E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 Gene3D G3DSA:3.40.50.720 5 248 6.1E-41 T 13-10-2018 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 Pfam PF01565 FAD binding domain 303 437 3.1E-27 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 Gene3D G3DSA:3.40.462.20 470 666 7.3E-70 T 13-10-2018 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 SUPERFAMILY SSF51735 5 231 5.26E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1001605 92fb442c304d48627b7282159a47cc5b 705 Pfam PF00106 short chain dehydrogenase 5 193 1.9E-23 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR MADE_1005270 0986fd50370d0427094f967152244dd0 179 Pfam PF06776 Invasion associated locus B (IalB) protein 45 170 3.0E-16 T 13-10-2018 IPR010642 Invasion protein B MADE_1005270 0986fd50370d0427094f967152244dd0 179 Gene3D G3DSA:2.60.40.1880 39 179 3.6E-13 T 13-10-2018 IPR038696 Invasion protein B superfamily MADE_1012070 19d28a474ab9f4e24a5c71dc2638e8f0 222 Pfam PF04315 Elongation factor P hydroxylase 58 214 1.7E-73 T 13-10-2018 IPR007411 Elongation factor P hydroxylase MADE_1014500 e040acea6d9450387c8907d9874395da 190 SUPERFAMILY SSF53098 4 180 1.17E-20 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1014500 e040acea6d9450387c8907d9874395da 190 Gene3D G3DSA:3.30.420.10 1 185 7.6E-11 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 MADE_1014500 e040acea6d9450387c8907d9874395da 190 Pfam PF16473 3' exoribonuclease, RNase T-like 3 177 5.9E-50 T 13-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain MADE_1005980 d1f1167a311a5034934dd2410f44e0fb 288 PIRSF PIRSF003092 2 282 7.9E-83 T 13-10-2018 IPR025501 ATP binding protein MinD MADE_1005980 d1f1167a311a5034934dd2410f44e0fb 288 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 19 257 5.5E-22 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 MADE_1005980 d1f1167a311a5034934dd2410f44e0fb 288 Gene3D G3DSA:3.40.50.300 18 258 2.3E-60 T 13-10-2018 MADE_1005980 d1f1167a311a5034934dd2410f44e0fb 288 SUPERFAMILY SSF52540 19 278 4.91E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 Gene3D G3DSA:3.60.120.10 19 483 3.1E-153 T 13-10-2018 IPR005801 ADC synthase GO:0009058 MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 SUPERFAMILY SSF56322 26 482 3.66E-131 T 13-10-2018 IPR005801 ADC synthase GO:0009058 MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 Pfam PF00425 chorismate binding enzyme 220 473 8.5E-94 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 Pfam PF04715 Anthranilate synthase component I, N terminal region 35 177 5.1E-17 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 131 476 5.1E-106 T 13-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 PRINTS PR00095 Anthranilate synthase component I signature 321 334 1.1E-11 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 PRINTS PR00095 Anthranilate synthase component I signature 430 444 1.1E-11 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 PRINTS PR00095 Anthranilate synthase component I signature 335 348 1.1E-11 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_1009870 9541783b2e0e7732dde17c8683b970fa 486 PRINTS PR00095 Anthranilate synthase component I signature 415 429 1.1E-11 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 MADE_000001022060 6e65251703044e7ad8e46bdadab0caa5 268 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 132 262 1.7E-14 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MADE_000001022060 6e65251703044e7ad8e46bdadab0caa5 268 SMART SM00047 116 252 0.0077 T 13-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 MADE_000001022060 6e65251703044e7ad8e46bdadab0caa5 268 Gene3D G3DSA:1.10.530.10 124 264 1.5E-12 T 13-10-2018 MADE_1002725 90227230251626ddf8b498bebf5c375e 387 Pfam PF01551 Peptidase family M23 289 382 1.0E-23 T 13-10-2018 IPR016047 Peptidase M23 MADE_1002725 90227230251626ddf8b498bebf5c375e 387 Gene3D G3DSA:2.70.70.10 249 387 8.2E-34 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1002725 90227230251626ddf8b498bebf5c375e 387 SUPERFAMILY SSF51261 143 386 2.62E-44 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 PIRSF PIRSF002764 1 221 1.7E-73 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 194 217 2.2E-56 T 13-10-2018 MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 28 49 2.2E-56 T 13-10-2018 MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 54 71 2.2E-56 T 13-10-2018 MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 133 156 2.2E-56 T 13-10-2018 MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 77 100 2.2E-56 T 13-10-2018 MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 102 120 2.2E-56 T 13-10-2018 MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 7 217 4.9E-75 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria MADE_1004765 9c509b378297b3248457bb541d7ce3ad 221 Pfam PF03379 CcmB protein 7 218 9.4E-75 T 13-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_000001022320 aafc3dfebf8010fefaba117811a07f2d 96 Pfam PF03050 Transposase IS66 family 1 30 3.4E-7 T 13-10-2018 IPR004291 Transposase, IS66 MADE_000001022320 aafc3dfebf8010fefaba117811a07f2d 96 Pfam PF13817 IS66 C-terminal element 37 73 2.8E-12 T 13-10-2018 IPR039552 Transposase IS66, C-terminal MADE_000001021900 cd716b8fec7ed9c319d89e07655f7144 247 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 6 245 56.531 T 13-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_000001021900 cd716b8fec7ed9c319d89e07655f7144 247 ProSitePatterns PS00171 Triosephosphate isomerase active site. 162 172 - T 13-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_000001021900 cd716b8fec7ed9c319d89e07655f7144 247 Gene3D G3DSA:3.20.20.70 1 247 2.0E-91 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_000001021900 cd716b8fec7ed9c319d89e07655f7144 247 Pfam PF00121 Triosephosphate isomerase 9 243 4.4E-83 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_000001021900 cd716b8fec7ed9c319d89e07655f7144 247 SUPERFAMILY SSF51351 5 245 5.11E-87 T 13-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_000001021900 cd716b8fec7ed9c319d89e07655f7144 247 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 9 237 8.1E-61 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 MADE_1015695 7df17b4387b5ba3957840d4de503d7b2 291 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 1 288 49.718 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MADE_1015695 7df17b4387b5ba3957840d4de503d7b2 291 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 251 3.7E-52 T 13-10-2018 MADE_1015695 7df17b4387b5ba3957840d4de503d7b2 291 Gene3D G3DSA:3.20.20.60 1 291 1.7E-106 T 13-10-2018 MADE_1015695 7df17b4387b5ba3957840d4de503d7b2 291 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 4 287 1.1E-129 T 13-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 MADE_1015695 7df17b4387b5ba3957840d4de503d7b2 291 SUPERFAMILY SSF51621 4 286 4.22E-101 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 MADE_1015695 7df17b4387b5ba3957840d4de503d7b2 291 ProSitePatterns PS00161 Isocitrate lyase signature. 117 122 - T 13-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 MADE_1011070 889c87c93e68550313f094efdbeed124 100 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 91 2.9E-16 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1011070 889c87c93e68550313f094efdbeed124 100 Gene3D G3DSA:3.30.2310.20 1 92 2.6E-15 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1004465 fbff94c0bfd22024092858bcf872ede0 515 Gene3D G3DSA:3.30.160.720 359 411 9.9E-13 T 13-10-2018 MADE_1004465 fbff94c0bfd22024092858bcf872ede0 515 SUPERFAMILY SSF56300 24 341 4.72E-53 T 13-10-2018 MADE_1004465 fbff94c0bfd22024092858bcf872ede0 515 Gene3D G3DSA:3.60.21.10 16 316 5.2E-83 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like MADE_1004465 fbff94c0bfd22024092858bcf872ede0 515 Pfam PF00149 Calcineurin-like phosphoesterase 24 265 2.2E-13 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MADE_1004465 fbff94c0bfd22024092858bcf872ede0 515 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 24 293 1.6E-67 T 13-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 MADE_1004465 fbff94c0bfd22024092858bcf872ede0 515 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 316 444 6.2E-23 T 13-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain MADE_1000125 5ea940bb33235d76db281403978643b8 180 SUPERFAMILY SSF57783 22 61 1.31E-10 T 13-10-2018 MADE_1000125 5ea940bb33235d76db281403978643b8 180 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 21 56 3.6E-14 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MADE_1000125 5ea940bb33235d76db281403978643b8 180 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 111 147 3.8E-12 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MADE_1000125 5ea940bb33235d76db281403978643b8 180 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 70 105 8.9E-14 T 13-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 MADE_1000125 5ea940bb33235d76db281403978643b8 180 Gene3D G3DSA:3.30.65.10 66 112 1.9E-5 T 13-10-2018 MADE_1000125 5ea940bb33235d76db281403978643b8 180 Gene3D G3DSA:3.30.65.10 14 65 2.7E-5 T 13-10-2018 MADE_1000125 5ea940bb33235d76db281403978643b8 180 SUPERFAMILY SSF57783 111 146 6.63E-5 T 13-10-2018 MADE_1000125 5ea940bb33235d76db281403978643b8 180 SUPERFAMILY SSF57783 66 108 1.87E-11 T 13-10-2018 MADE_1009185 d61c3bfc6d8e9ab388c46009500561e1 656 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 495 8.1E-191 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MADE_1009185 d61c3bfc6d8e9ab388c46009500561e1 656 ProSitePatterns PS01303 BCCT family of transporters signature. 314 323 - T 13-10-2018 IPR018093 BCCT transporter, conserved site MADE_1009185 d61c3bfc6d8e9ab388c46009500561e1 656 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 52 495 1.3E-158 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 MADE_000001021445 6ad9a8fb88df80f20f13ade9afe1752b 62 Pfam PF06945 Protein of unknown function (DUF1289) 5 47 3.5E-19 T 13-10-2018 IPR010710 Protein of unknown function DUF1289 MADE_1001960 89fdf80790d51356667c00430a9ce0a2 441 Pfam PF13520 Amino acid permease 13 398 2.7E-29 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MADE_1001960 89fdf80790d51356667c00430a9ce0a2 441 Gene3D G3DSA:1.20.1740.10 7 435 1.4E-79 T 13-10-2018 MADE_1001960 89fdf80790d51356667c00430a9ce0a2 441 PIRSF PIRSF006060 1 441 1.1E-62 T 13-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 MADE_1013765 b578fb28d536ee9965f6b8c882f0b0f9 102 Gene3D G3DSA:2.60.40.10 3 98 1.3E-16 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1013765 b578fb28d536ee9965f6b8c882f0b0f9 102 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 15 87 2.7E-7 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 MADE_1013765 b578fb28d536ee9965f6b8c882f0b0f9 102 SUPERFAMILY SSF81296 13 98 9.33E-15 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1008130 0cb295e6513791634161c338a139b100 251 SUPERFAMILY SSF48452 58 152 3.6E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1008130 0cb295e6513791634161c338a139b100 251 Gene3D G3DSA:1.25.40.10 32 207 7.8E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1006420 c70796d012e09f702193848cb7746868 404 Gene3D G3DSA:3.60.10.10 28 403 2.5E-20 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1006420 c70796d012e09f702193848cb7746868 404 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 33 391 3.1E-23 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase MADE_1006420 c70796d012e09f702193848cb7746868 404 SUPERFAMILY SSF56219 30 399 2.36E-21 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily MADE_1003105 5b72783ea6299cf89c8216439e33ed2a 86 Gene3D G3DSA:3.30.2020.10 2 78 7.7E-11 T 13-10-2018 IPR036782 NE0471-like, N-terminal MADE_1003105 5b72783ea6299cf89c8216439e33ed2a 86 SUPERFAMILY SSF143880 2 78 2.22E-22 T 13-10-2018 IPR036782 NE0471-like, N-terminal MADE_1003105 5b72783ea6299cf89c8216439e33ed2a 86 Pfam PF10387 Protein of unknown function (DUF2442) 4 76 1.0E-18 T 13-10-2018 IPR018841 Protein of unknown function DUF2442 MADE_1015200 3b4686d539eda1b85aea35929a5ecc13 274 SUPERFAMILY SSF56935 72 273 2.75E-7 T 13-10-2018 MADE_1006520 6389c6eb68db66c18b457edaa4e7f0ba 216 Pfam PF01713 Smr domain 133 207 9.5E-18 T 13-10-2018 IPR002625 Smr domain MADE_1006520 6389c6eb68db66c18b457edaa4e7f0ba 216 SMART SM00463 130 208 2.1E-13 T 13-10-2018 IPR002625 Smr domain MADE_1006520 6389c6eb68db66c18b457edaa4e7f0ba 216 SUPERFAMILY SSF160443 130 205 4.58E-10 T 13-10-2018 IPR036063 Smr domain superfamily MADE_1006520 6389c6eb68db66c18b457edaa4e7f0ba 216 Gene3D G3DSA:3.30.1370.110 85 210 1.3E-26 T 13-10-2018 MADE_000001023220 b12d3a46032953f71f2eb0ba398d9bcb 476 Pfam PF02321 Outer membrane efflux protein 290 465 6.1E-14 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_000001023220 b12d3a46032953f71f2eb0ba398d9bcb 476 Gene3D G3DSA:1.20.1600.10 28 469 1.5E-43 T 13-10-2018 MADE_000001023220 b12d3a46032953f71f2eb0ba398d9bcb 476 SUPERFAMILY SSF56954 7 468 3.14E-37 T 13-10-2018 MADE_1001445 d82dae09435638b1c12d6c51e95bd275 297 SUPERFAMILY SSF56349 111 294 6.47E-44 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1001445 d82dae09435638b1c12d6c51e95bd275 297 Pfam PF00589 Phage integrase family 113 282 1.4E-28 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 MADE_1001445 d82dae09435638b1c12d6c51e95bd275 297 Gene3D G3DSA:1.10.443.10 106 296 9.3E-43 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1000475 cf6cf27e9e8c61649f6c694d6988e096 216 Gene3D G3DSA:3.30.1020.20 153 216 2.1E-20 T 13-10-2018 MADE_1000475 cf6cf27e9e8c61649f6c694d6988e096 216 Gene3D G3DSA:3.40.30.10 13 152 7.7E-49 T 13-10-2018 MADE_1000475 cf6cf27e9e8c61649f6c694d6988e096 216 Pfam PF00578 AhpC/TSA family 15 143 1.3E-36 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1000475 cf6cf27e9e8c61649f6c694d6988e096 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 164 200 4.8E-12 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1000475 cf6cf27e9e8c61649f6c694d6988e096 216 SUPERFAMILY SSF52833 12 215 2.78E-70 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1000475 cf6cf27e9e8c61649f6c694d6988e096 216 Hamap MF_00401 Peroxiredoxin. 12 216 42.613 T 13-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MADE_1000475 cf6cf27e9e8c61649f6c694d6988e096 216 PIRSF PIRSF000239 7 216 8.2E-75 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1014505 eb8f6a305fcdcbf877aca39f954703fc 215 SUPERFAMILY SSF47413 12 85 2.08E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1014505 eb8f6a305fcdcbf877aca39f954703fc 215 Gene3D G3DSA:1.10.260.40 4 85 1.0E-11 T 13-10-2018 MADE_1009010 3b9389fb1bc87837a51ae8849d8eba4b 497 Pfam PF03929 PepSY-associated TM region 11 353 6.3E-54 T 13-10-2018 IPR005625 PepSY-associated TM protein MADE_1003030 c375d89c3fc4e3dbd83128cc967df722 151 SUPERFAMILY SSF55729 1 149 1.05E-24 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1003030 c375d89c3fc4e3dbd83128cc967df722 151 Pfam PF00583 Acetyltransferase (GNAT) family 41 129 5.1E-11 T 13-10-2018 IPR000182 GNAT domain MADE_1003030 c375d89c3fc4e3dbd83128cc967df722 151 Gene3D G3DSA:3.40.630.30 1 151 3.4E-36 T 13-10-2018 MADE_1015885 2348ea1e560083524f884a67ae94eee5 330 Gene3D G3DSA:3.40.50.720 57 322 1.1E-93 T 13-10-2018 MADE_1015885 2348ea1e560083524f884a67ae94eee5 330 SUPERFAMILY SSF51735 115 296 2.15E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1015885 2348ea1e560083524f884a67ae94eee5 330 Gene3D G3DSA:3.40.50.720 113 299 1.1E-93 T 13-10-2018 MADE_1015885 2348ea1e560083524f884a67ae94eee5 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 295 1.1E-47 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 MADE_1010870 f2e3e651151377bf16994eae8ac17af1 245 Gene3D G3DSA:1.10.8.60 178 244 1.4E-18 T 13-10-2018 MADE_1010870 f2e3e651151377bf16994eae8ac17af1 245 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 2 242 2.0E-65 T 13-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 MADE_1010870 f2e3e651151377bf16994eae8ac17af1 245 Gene3D G3DSA:3.40.50.300 1 174 1.7E-27 T 13-10-2018 MADE_1010870 f2e3e651151377bf16994eae8ac17af1 245 Pfam PF00308 Bacterial dnaA protein 59 226 2.8E-12 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA MADE_1010870 f2e3e651151377bf16994eae8ac17af1 245 SUPERFAMILY SSF52540 11 222 2.17E-22 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015465 bea97a61e40d55d39752ae4997ecc323 221 SMART SM00986 48 209 1.3E-41 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1015465 bea97a61e40d55d39752ae4997ecc323 221 SMART SM00987 48 209 1.3E-41 T 13-10-2018 MADE_1015465 bea97a61e40d55d39752ae4997ecc323 221 Pfam PF03167 Uracil DNA glycosylase superfamily 53 208 2.2E-25 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1015465 bea97a61e40d55d39752ae4997ecc323 221 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 5 213 2.3E-86 T 13-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1015465 bea97a61e40d55d39752ae4997ecc323 221 Gene3D G3DSA:3.40.470.10 1 221 5.2E-104 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1015465 bea97a61e40d55d39752ae4997ecc323 221 SUPERFAMILY SSF52141 4 220 2.18E-95 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1015465 bea97a61e40d55d39752ae4997ecc323 221 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 3 220 40.461 T 13-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 MADE_1019910 c0d0a7ca269c7dec29bf73dbe4d3a206 194 Pfam PF04264 YceI-like domain 26 192 2.6E-15 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MADE_1019910 c0d0a7ca269c7dec29bf73dbe4d3a206 194 PIRSF PIRSF029811 1 194 4.2E-59 T 13-10-2018 IPR027016 Uncharacterised protein with YceI domain MADE_1019910 c0d0a7ca269c7dec29bf73dbe4d3a206 194 Gene3D G3DSA:2.40.128.110 22 194 4.9E-52 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MADE_1019910 c0d0a7ca269c7dec29bf73dbe4d3a206 194 SMART SM00867 25 193 8.4E-20 T 13-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like MADE_1019910 c0d0a7ca269c7dec29bf73dbe4d3a206 194 SUPERFAMILY SSF101874 22 193 3.4E-25 T 13-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily MADE_1016250 98a6d954075dbdf5a39c67ff93aa95b8 378 Gene3D G3DSA:1.10.3470.10 31 376 3.2E-96 T 13-10-2018 IPR037294 ABC transporter, BtuC-like MADE_1016250 98a6d954075dbdf5a39c67ff93aa95b8 378 Pfam PF01032 FecCD transport family 43 368 1.3E-87 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 MADE_1016250 98a6d954075dbdf5a39c67ff93aa95b8 378 SUPERFAMILY SSF81345 28 369 1.83E-79 T 13-10-2018 IPR037294 ABC transporter, BtuC-like MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 550 580 - T 13-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 Gene3D G3DSA:2.130.10.120 113 449 3.5E-250 T 13-10-2018 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 48 446 1.8E-102 T 13-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 Gene3D G3DSA:3.40.50.1820 58 714 3.5E-250 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 Pfam PF00326 Prolyl oligopeptidase family 506 718 4.6E-64 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 SUPERFAMILY SSF50993 43 450 8.89E-86 T 13-10-2018 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 SUPERFAMILY SSF53474 457 716 1.47E-48 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 515 539 5.4E-58 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 543 562 5.4E-58 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 573 593 5.4E-58 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 629 644 5.4E-58 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 489 507 5.4E-58 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1013750 9849fa874b4d0df989bef4690a803b88 719 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 648 670 5.4E-58 T 13-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 MADE_1004840 474c0a5512f840aedf11da8943dd6f19 609 Gene3D G3DSA:3.10.560.10 130 292 1.2E-14 T 13-10-2018 MADE_1004840 474c0a5512f840aedf11da8943dd6f19 609 Pfam PF02563 Polysaccharide biosynthesis/export protein 130 203 1.2E-12 T 13-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 MADE_1004840 474c0a5512f840aedf11da8943dd6f19 609 Gene3D G3DSA:3.30.1950.10 136 207 1.2E-14 T 13-10-2018 MADE_1004840 474c0a5512f840aedf11da8943dd6f19 609 Gene3D G3DSA:3.10.560.10 501 579 1.6E-10 T 13-10-2018 MADE_1006220 c723f3ced0abf5f5c5cda47296700586 935 Gene3D G3DSA:2.170.130.10 37 170 2.6E-40 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1006220 c723f3ced0abf5f5c5cda47296700586 935 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 165 3.8E-28 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1006220 c723f3ced0abf5f5c5cda47296700586 935 SUPERFAMILY SSF56935 42 935 2.35E-103 T 13-10-2018 MADE_1006220 c723f3ced0abf5f5c5cda47296700586 935 Pfam PF00593 TonB dependent receptor 346 929 6.0E-46 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1013410 2f68a04156e5d81c81526ca846f8307d 406 Pfam PF00155 Aminotransferase class I and II 36 381 6.9E-55 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 MADE_1013410 2f68a04156e5d81c81526ca846f8307d 406 Gene3D G3DSA:3.90.1150.10 22 398 9.5E-141 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1013410 2f68a04156e5d81c81526ca846f8307d 406 SUPERFAMILY SSF53383 7 401 5.39E-93 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1013410 2f68a04156e5d81c81526ca846f8307d 406 Gene3D G3DSA:3.40.640.10 53 294 9.5E-141 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1000350 1369b074d01d149eb5026d2af646b676 124 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 5 123 3.9E-42 T 13-10-2018 IPR009387 Toxin HigB-2 MADE_1000350 1369b074d01d149eb5026d2af646b676 124 PIRSF PIRSF018634 4 124 9.3E-39 T 13-10-2018 IPR009387 Toxin HigB-2 MADE_1007690 66d0c52770d8e295dd2d50cbd68f4339 150 Pfam PF04241 Protein of unknown function (DUF423) 29 115 9.0E-32 T 13-10-2018 IPR006696 Protein of unknown function DUF423 MADE_1003755 405b2e06dd7f8fa1588321687720b93c 640 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 39 - T 13-10-2018 IPR010916 TonB box, conserved site MADE_1003755 405b2e06dd7f8fa1588321687720b93c 640 Gene3D G3DSA:2.170.130.10 27 157 8.8E-29 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1003755 405b2e06dd7f8fa1588321687720b93c 640 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 152 1.3E-24 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1003755 405b2e06dd7f8fa1588321687720b93c 640 Pfam PF00593 TonB dependent receptor 175 639 3.3E-44 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1003755 405b2e06dd7f8fa1588321687720b93c 640 SUPERFAMILY SSF56935 30 639 5.23E-104 T 13-10-2018 MADE_1003755 405b2e06dd7f8fa1588321687720b93c 640 Gene3D G3DSA:2.40.170.20 164 640 5.6E-87 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1003075 74e08516aa12755163519720ad151c24 97 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 82 2.8E-7 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1003075 74e08516aa12755163519720ad151c24 97 Gene3D G3DSA:3.30.2310.20 1 95 3.1E-25 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1003075 74e08516aa12755163519720ad151c24 97 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 84 1.5E-12 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1003075 74e08516aa12755163519720ad151c24 97 SUPERFAMILY SSF143011 1 82 4.05E-21 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_000001021275 1c9babcedcb5c1ccf8ce772fd17cbeaa 63 Gene3D G3DSA:3.40.50.720 1 62 1.2E-9 T 13-10-2018 MADE_000001021275 1c9babcedcb5c1ccf8ce772fd17cbeaa 63 SUPERFAMILY SSF51735 2 61 8.4E-8 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1010830 5696d1c552c5d25bd345b38522112959 187 Gene3D G3DSA:3.30.70.260 89 175 9.2E-11 T 13-10-2018 MADE_1010830 5696d1c552c5d25bd345b38522112959 187 Pfam PF13740 ACT domain 4 78 1.3E-18 T 13-10-2018 MADE_1010830 5696d1c552c5d25bd345b38522112959 187 SUPERFAMILY SSF55021 3 84 1.47E-13 T 13-10-2018 MADE_1010830 5696d1c552c5d25bd345b38522112959 187 Gene3D G3DSA:3.30.70.260 2 86 6.4E-18 T 13-10-2018 MADE_1010830 5696d1c552c5d25bd345b38522112959 187 PIRSF PIRSF028103 2 177 7.1E-39 T 13-10-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 MADE_1010830 5696d1c552c5d25bd345b38522112959 187 SUPERFAMILY SSF55021 92 173 2.86E-11 T 13-10-2018 MADE_1016835 0d00216b24dfc66ecb3d75c5a248c43b 276 Pfam PF11185 Protein of unknown function (DUF2971) 127 215 8.0E-12 T 13-10-2018 IPR021352 Protein of unknown function DUF2971 MADE_1001845 ff26dca297647eae10716fe0e2c198eb 253 Pfam PF03050 Transposase IS66 family 2 204 5.9E-35 T 13-10-2018 IPR004291 Transposase, IS66 MADE_000001023390 2f5e90ddcf92442b49d3356ef5f17267 316 Gene3D G3DSA:3.20.20.100 1 316 6.8E-88 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_000001023390 2f5e90ddcf92442b49d3356ef5f17267 316 Pfam PF00248 Aldo/keto reductase family 11 306 1.2E-55 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain MADE_000001023390 2f5e90ddcf92442b49d3356ef5f17267 316 SUPERFAMILY SSF51430 8 314 8.12E-69 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily MADE_1004600 cf3c9c0773dd1a44d331967073214e42 269 TIGRFAM TIGR04052 AZL_007920_fam: AZL_007920/MXAN_0976 family protein 65 259 4.6E-36 T 13-10-2018 IPR023977 Conserved hypotheical protein CHP04052 MADE_1011645 1f324564060255d1f65f30db2ba1b23b 294 Pfam PF11207 Protein of unknown function (DUF2989) 38 238 1.6E-61 T 13-10-2018 IPR021372 Protein of unknown function DUF2989 MADE_1002740 dea28d631cbfc1b0216ed779f07ebac5 229 SUPERFAMILY SSF51695 1 228 9.68E-58 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MADE_1002740 dea28d631cbfc1b0216ed779f07ebac5 229 Gene3D G3DSA:3.20.20.190 1 229 9.6E-59 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 MADE_1002740 dea28d631cbfc1b0216ed779f07ebac5 229 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 223 3.2E-32 T 13-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 MADE_1019725 6f72c3b02f573f7dedea5f3f784c6b36 292 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 284 1.9E-98 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MADE_1019725 6f72c3b02f573f7dedea5f3f784c6b36 292 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 291 31.879 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MADE_1019725 6f72c3b02f573f7dedea5f3f784c6b36 292 PIRSF PIRSF000401 1 292 6.5E-91 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 MADE_1019725 6f72c3b02f573f7dedea5f3f784c6b36 292 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 291 3.5E-96 T 13-10-2018 MADE_1019725 6f72c3b02f573f7dedea5f3f784c6b36 292 SUPERFAMILY SSF53335 66 270 1.03E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1019725 6f72c3b02f573f7dedea5f3f784c6b36 292 Gene3D G3DSA:3.40.50.150 101 292 1.3E-55 T 13-10-2018 MADE_1013185 4bed881b9321fad9151d022bd7421eb2 434 SUPERFAMILY SSF53756 127 361 1.15E-21 T 13-10-2018 MADE_1013185 4bed881b9321fad9151d022bd7421eb2 434 Pfam PF00534 Glycosyl transferases group 1 213 325 3.5E-16 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1013185 4bed881b9321fad9151d022bd7421eb2 434 Gene3D G3DSA:3.40.50.2000 205 374 2.2E-19 T 13-10-2018 MADE_1019380 c6613d8f181e5ef876b6c1d9c1095eec 297 Pfam PF01136 Peptidase family U32 92 247 1.6E-14 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MADE_1005300 15498cc80e59009d43cdd31431f74d30 239 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 6 151 2.9E-39 T 13-10-2018 IPR023370 YaeB-like, N-terminal domain MADE_1005300 15498cc80e59009d43cdd31431f74d30 239 Pfam PF01980 Uncharacterised protein family UPF0066 24 145 1.0E-34 T 13-10-2018 IPR023370 YaeB-like, N-terminal domain MADE_1005300 15498cc80e59009d43cdd31431f74d30 239 SUPERFAMILY SSF118196 7 233 8.11E-68 T 13-10-2018 IPR036413 YaeB-like superfamily MADE_1005300 15498cc80e59009d43cdd31431f74d30 239 Gene3D G3DSA:3.30.2310.10 159 234 3.4E-15 T 13-10-2018 MADE_1005300 15498cc80e59009d43cdd31431f74d30 239 Gene3D G3DSA:2.40.30.70 9 158 4.6E-42 T 13-10-2018 IPR036414 YaeB, N-terminal domain superfamily MADE_1019065 5a4d75d3720de995c48c89db15c36192 37 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 30 3.6E-20 T 13-10-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 MADE_1019065 5a4d75d3720de995c48c89db15c36192 37 Pfam PF08173 Membrane bound YbgT-like protein 1 26 1.9E-17 T 13-10-2018 IPR012994 Membrane bound YbgT-like MADE_1016725 c9e9ce6dd11c789964cc0794b83e2e43 301 Pfam PF10987 Protein of unknown function (DUF2806) 74 291 2.2E-72 T 13-10-2018 IPR021254 Protein of unknown function DUF2806 MADE_1016725 c9e9ce6dd11c789964cc0794b83e2e43 301 TIGRFAM TIGR03899 TIGR03899: TIGR03899 family protein 51 300 4.8E-95 T 13-10-2018 IPR021254 Protein of unknown function DUF2806 MADE_1016345 683aa665555a9dc8fe1c7d069380002c 306 Pfam PF13737 Transposase DDE domain 19 129 7.2E-44 T 13-10-2018 IPR025668 Transposase DDE domain MADE_1007490 59b9f7011cba1664c7cf215b1c93dd7f 476 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 171 263 4.5E-18 T 13-10-2018 IPR026392 Exosortase/Archaeosortase domain MADE_1007490 59b9f7011cba1664c7cf215b1c93dd7f 476 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 14 263 5.2E-55 T 13-10-2018 IPR019127 Exosortase MADE_1007490 59b9f7011cba1664c7cf215b1c93dd7f 476 Pfam PF11984 Protein of unknown function (DUF3485) 327 463 1.8E-11 T 13-10-2018 IPR014263 Methanolan biosynthesis EpsI MADE_1007490 59b9f7011cba1664c7cf215b1c93dd7f 476 TIGRFAM TIGR02602 8TM_EpsH: exosortase 29 262 7.5E-60 T 13-10-2018 IPR013426 Exosortase, EpsH-like MADE_1006645 8dc73fb5e9312dfb79cb473b2d7e4f4e 362 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 352 9.0E-127 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 MADE_1006645 8dc73fb5e9312dfb79cb473b2d7e4f4e 362 Pfam PF03116 NQR2, RnfD, RnfE family 5 351 6.3E-103 T 13-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 MADE_1006645 8dc73fb5e9312dfb79cb473b2d7e4f4e 362 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 3 353 26.576 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 MADE_1006210 e3d8975abf7901f5b18e62b3b6357082 362 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 3 340 33.467 T 13-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MADE_1006210 e3d8975abf7901f5b18e62b3b6357082 362 Gene3D G3DSA:1.20.58.480 8 237 7.6E-69 T 13-10-2018 MADE_1006210 e3d8975abf7901f5b18e62b3b6357082 362 Pfam PF03301 Tryptophan 2,3-dioxygenase 9 340 5.1E-100 T 13-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MADE_1006210 e3d8975abf7901f5b18e62b3b6357082 362 SUPERFAMILY SSF140959 10 340 1.37E-77 T 13-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 SUPERFAMILY SSF50104 7 119 2.81E-46 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 8 118 4.0E-51 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 ProSitePatterns PS01015 Ribosomal protein L19 signature. 91 106 - T 13-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 Gene3D G3DSA:2.30.30.790 1 120 3.6E-14 T 13-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 Pfam PF01245 Ribosomal protein L19 9 118 5.1E-50 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 7 119 31.362 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 PRINTS PR00061 Ribosomal protein L19 signature 93 118 2.7E-41 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 PRINTS PR00061 Ribosomal protein L19 signature 39 68 2.7E-41 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 PRINTS PR00061 Ribosomal protein L19 signature 9 38 2.7E-41 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_000001021065 1df1b85ab9f639beba904f84103f4f7b 120 PIRSF PIRSF002191 1 120 6.1E-51 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 MADE_1006830 a925876182b1212ac17d6a9d4ad21c07 840 Pfam PF02687 FtsX-like permease family 743 830 5.4E-7 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MADE_1006830 a925876182b1212ac17d6a9d4ad21c07 840 Pfam PF02687 FtsX-like permease family 289 376 5.7E-9 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MADE_1006830 a925876182b1212ac17d6a9d4ad21c07 840 Pfam PF12704 MacB-like periplasmic core domain 23 200 2.6E-6 T 13-10-2018 IPR025857 MacB-like periplasmic core domain MADE_1001075 14add51fc845dd33d98df360b87187d0 232 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 130 220 6.9E-12 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MADE_1001075 14add51fc845dd33d98df360b87187d0 232 SMART SM00702 3 221 2.4E-4 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MADE_1000460 a811af4bbabf77fd4a8fdb683b2abe1d 465 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 434 7.1E-150 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MADE_1000460 a811af4bbabf77fd4a8fdb683b2abe1d 465 PIRSF PIRSF006446 1 456 3.5E-170 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MADE_1005870 af853a5804eafe974cce5be975eabccb 332 Pfam PF02719 Polysaccharide biosynthesis protein 7 279 2.0E-101 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain MADE_1005870 af853a5804eafe974cce5be975eabccb 332 Gene3D G3DSA:3.90.25.30 167 315 1.5E-130 T 13-10-2018 MADE_1005870 af853a5804eafe974cce5be975eabccb 332 Gene3D G3DSA:3.40.50.720 5 311 1.5E-130 T 13-10-2018 MADE_1005870 af853a5804eafe974cce5be975eabccb 332 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 1 326 2.2E-168 T 13-10-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00520+4.2.1.115|MetaCyc: PWY-6143|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 MADE_1005870 af853a5804eafe974cce5be975eabccb 332 SUPERFAMILY SSF51735 1 260 1.78E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_000001023475 04f33f204c99895ddcbfaf4fd7ac863b 305 PIRSF PIRSF037505 2 183 1.6E-6 T 13-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 MADE_000001023475 04f33f204c99895ddcbfaf4fd7ac863b 305 PIRSF PIRSF037505 259 304 0.0091 T 13-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 MADE_000001023475 04f33f204c99895ddcbfaf4fd7ac863b 305 SUPERFAMILY SSF82282 6 303 6.93E-76 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MADE_000001023475 04f33f204c99895ddcbfaf4fd7ac863b 305 Gene3D G3DSA:3.20.20.330 2 298 4.5E-68 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 MADE_000001023475 04f33f204c99895ddcbfaf4fd7ac863b 305 Pfam PF02574 Homocysteine S-methyltransferase 10 298 1.2E-57 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 MADE_1014455 ee666c3f6c0d4bcf94cc18288472a65f 544 Pfam PF02652 L-lactate permease 8 533 8.6E-99 T 13-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 MADE_1020245 7d8c2cd0bce0ef8a47223cea84832db3 430 SUPERFAMILY SSF51556 80 391 1.26E-108 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1020245 7d8c2cd0bce0ef8a47223cea84832db3 430 Gene3D G3DSA:2.30.40.10 29 425 1.2E-139 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1020245 7d8c2cd0bce0ef8a47223cea84832db3 430 SUPERFAMILY SSF51338 21 427 1.5E-14 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 MADE_1020245 7d8c2cd0bce0ef8a47223cea84832db3 430 Pfam PF01979 Amidohydrolase family 76 426 1.4E-51 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 MADE_1020245 7d8c2cd0bce0ef8a47223cea84832db3 430 Gene3D G3DSA:3.20.20.140 82 390 1.2E-139 T 13-10-2018 MADE_1002125 ce2cda902329a9d0a04e2026de6c4769 382 SUPERFAMILY SSF56796 5 379 6.41E-119 T 13-10-2018 MADE_1002125 ce2cda902329a9d0a04e2026de6c4769 382 Gene3D G3DSA:1.20.1090.10 183 381 4.3E-65 T 13-10-2018 MADE_1002125 ce2cda902329a9d0a04e2026de6c4769 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 374 1.0E-111 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 MADE_1002125 ce2cda902329a9d0a04e2026de6c4769 382 Gene3D G3DSA:3.40.50.1970 1 182 8.2E-52 T 13-10-2018 MADE_1000325 5e89668272bd24a287b0beb6706b36a0 103 Pfam PF00581 Rhodanese-like domain 16 96 8.8E-15 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1000325 5e89668272bd24a287b0beb6706b36a0 103 SMART SM00450 5 100 1.8E-18 T 13-10-2018 IPR001763 Rhodanese-like domain MADE_1000325 5e89668272bd24a287b0beb6706b36a0 103 SUPERFAMILY SSF52821 1 98 5.76E-27 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1000325 5e89668272bd24a287b0beb6706b36a0 103 Gene3D G3DSA:3.40.250.10 1 100 4.9E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily MADE_1000325 5e89668272bd24a287b0beb6706b36a0 103 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 103 29.535 T 13-10-2018 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927 MADE_1001855 6741e74202eed332004a3769fad67ae7 580 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 71 236 4.2E-23 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MADE_1013485 c028221f2dcfeebc2c037b078b6b06f8 330 Gene3D G3DSA:3.40.50.720 175 329 5.0E-29 T 13-10-2018 MADE_1013485 c028221f2dcfeebc2c037b078b6b06f8 330 Pfam PF13478 XdhC Rossmann domain 176 317 1.4E-22 T 13-10-2018 IPR027051 XdhC Rossmann domain MADE_1013485 c028221f2dcfeebc2c037b078b6b06f8 330 Pfam PF02625 XdhC and CoxI family 16 80 3.1E-14 T 13-10-2018 IPR003777 XdhC- CoxI MADE_1007440 520595b7915cdce8d649cce6c237746a 95 SUPERFAMILY SSF53613 8 94 2.24E-19 T 13-10-2018 IPR029056 Ribokinase-like MADE_1007440 520595b7915cdce8d649cce6c237746a 95 Gene3D G3DSA:3.40.1190.20 2 95 5.0E-35 T 13-10-2018 IPR029056 Ribokinase-like MADE_1007440 520595b7915cdce8d649cce6c237746a 95 Pfam PF00294 pfkB family carbohydrate kinase 9 94 1.7E-12 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB MADE_1020085 d1fbc9514398a6a468bd6c84e4bac2a2 69 Pfam PF11137 Protein of unknown function (DUF2909) 3 62 2.8E-16 T 13-10-2018 IPR021313 Protein of unknown function DUF2909 MADE_1008350 a2f9cf594c7c5e29063459b663ee91e7 213 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 6 200 9.7E-14 T 13-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 MADE_1008350 a2f9cf594c7c5e29063459b663ee91e7 213 Gene3D G3DSA:1.10.1760.20 2 200 1.7E-6 T 13-10-2018 MADE_1012875 2e76ffcdf071af8284184d83baeae69f 136 Gene3D G3DSA:3.90.1010.10 1 136 4.6E-47 T 13-10-2018 MADE_1012875 2e76ffcdf071af8284184d83baeae69f 136 Pfam PF02657 Fe-S metabolism associated domain 11 130 1.2E-44 T 13-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like MADE_1012875 2e76ffcdf071af8284184d83baeae69f 136 SUPERFAMILY SSF82649 4 134 5.23E-44 T 13-10-2018 MADE_1006135 ad8fed1a202f9614e2fa1edb3bd94862 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 324 8.3E-20 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MADE_1006135 ad8fed1a202f9614e2fa1edb3bd94862 331 SUPERFAMILY SSF52540 3 259 1.3E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006135 ad8fed1a202f9614e2fa1edb3bd94862 331 SMART SM00382 32 239 2.9E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1006135 ad8fed1a202f9614e2fa1edb3bd94862 331 Pfam PF00005 ABC transporter 23 187 1.0E-21 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1006135 ad8fed1a202f9614e2fa1edb3bd94862 331 Gene3D G3DSA:3.40.50.300 2 330 1.9E-66 T 13-10-2018 MADE_1006135 ad8fed1a202f9614e2fa1edb3bd94862 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 306 7.8E-15 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 MADE_1010965 f8a3e5ef603578e8f31f8b169d128d5f 278 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 29 177 7.7E-13 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 MADE_1010965 f8a3e5ef603578e8f31f8b169d128d5f 278 SUPERFAMILY SSF52540 10 271 2.52E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1010965 f8a3e5ef603578e8f31f8b169d128d5f 278 Gene3D G3DSA:3.40.50.300 6 208 4.6E-27 T 13-10-2018 MADE_1010965 f8a3e5ef603578e8f31f8b169d128d5f 278 SMART SM00382 25 183 1.1E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1016660 40bf39030d4de939080e24fb73829e5f 343 SMART SM00849 34 249 1.2E-25 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1016660 40bf39030d4de939080e24fb73829e5f 343 SUPERFAMILY SSF56281 5 323 1.31E-72 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1016660 40bf39030d4de939080e24fb73829e5f 343 Gene3D G3DSA:3.60.15.10 14 276 4.6E-58 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like MADE_1016660 40bf39030d4de939080e24fb73829e5f 343 Gene3D G3DSA:1.10.10.10 278 327 1.8E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1016660 40bf39030d4de939080e24fb73829e5f 343 Pfam PF00753 Metallo-beta-lactamase superfamily 33 249 4.1E-27 T 13-10-2018 IPR001279 Metallo-beta-lactamase MADE_1000830 58089badfd6d721f807f9f3411c035b4 344 Pfam PF07751 Abi-like protein 21 174 2.6E-7 T 13-10-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like MADE_1014495 f01686b6e80c7155c0d72e3ceaea484b 200 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 24 165 2.3E-16 T 13-10-2018 IPR011978 Uncharacterised protein family UPF0149 MADE_1014495 f01686b6e80c7155c0d72e3ceaea484b 200 Pfam PF03695 Uncharacterised protein family (UPF0149) 24 186 1.5E-39 T 13-10-2018 IPR011978 Uncharacterised protein family UPF0149 MADE_1014495 f01686b6e80c7155c0d72e3ceaea484b 200 Gene3D G3DSA:1.20.120.740 14 200 1.2E-54 T 13-10-2018 MADE_1014495 f01686b6e80c7155c0d72e3ceaea484b 200 SUPERFAMILY SSF101327 17 185 9.81E-44 T 13-10-2018 IPR036255 YgfB-like superfamily MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 Gene3D G3DSA:1.10.220.30 12 97 1.9E-19 T 13-10-2018 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 Pfam PF01706 FliG C-terminal domain 231 337 1.6E-40 T 13-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 SUPERFAMILY SSF48029 127 338 9.94E-67 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 SUPERFAMILY SSF48029 14 129 2.22E-22 T 13-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PRINTS PR00954 Flagellar motor switch protein FliG signature 285 311 8.4E-59 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PRINTS PR00954 Flagellar motor switch protein FliG signature 47 73 8.4E-59 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PRINTS PR00954 Flagellar motor switch protein FliG signature 261 281 8.4E-59 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PRINTS PR00954 Flagellar motor switch protein FliG signature 127 150 8.4E-59 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PRINTS PR00954 Flagellar motor switch protein FliG signature 208 233 8.4E-59 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PRINTS PR00954 Flagellar motor switch protein FliG signature 239 259 8.4E-59 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PRINTS PR00954 Flagellar motor switch protein FliG signature 18 34 8.4E-59 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 PIRSF PIRSF003161 12 346 3.2E-115 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 Pfam PF14842 FliG N-terminal domain 17 118 1.2E-29 T 13-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 Pfam PF14841 FliG middle domain 129 200 3.1E-26 T 13-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 14 344 4.7E-99 T 13-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 Gene3D G3DSA:1.10.220.30 208 346 1.1E-42 T 13-10-2018 MADE_1005905 38b9ea00b1c5d44aab5d38034768b816 346 Gene3D G3DSA:1.10.220.30 101 206 3.5E-29 T 13-10-2018 MADE_1004275 e73116f09aca585ccc050d3568273a69 240 Gene3D G3DSA:3.30.70.980 83 235 2.1E-46 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1004275 e73116f09aca585ccc050d3568273a69 240 Gene3D G3DSA:1.10.10.200 17 78 1.4E-18 T 13-10-2018 IPR017856 Integrase-like, N-terminal MADE_1004275 e73116f09aca585ccc050d3568273a69 240 Gene3D G3DSA:3.30.70.980 127 204 2.1E-46 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1004275 e73116f09aca585ccc050d3568273a69 240 SUPERFAMILY SSF75625 1 236 3.27E-78 T 13-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1004275 e73116f09aca585ccc050d3568273a69 240 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 238 27.406 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1004275 e73116f09aca585ccc050d3568273a69 240 Pfam PF01709 Transcriptional regulator 5 236 9.0E-77 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1019080 f096a5dd4028674d881f0f40c8bc8925 200 Pfam PF11845 Protein of unknown function (DUF3365) 7 196 1.9E-25 T 13-10-2018 IPR021796 Protein of unknown function DUF3365 MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 SMART SM00100 13 134 2.1E-20 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 Gene3D G3DSA:2.60.120.10 5 142 1.2E-28 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 Pfam PF00027 Cyclic nucleotide-binding domain 32 119 3.3E-18 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 SUPERFAMILY SSF46785 150 227 2.33E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 SMART SM00419 170 218 7.5E-9 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 SUPERFAMILY SSF51206 7 141 1.2E-32 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 Pfam PF13545 Crp-like helix-turn-helix domain 153 222 2.9E-14 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 MADE_1011930 4c81680630dc10da730bfc28e1969bec 229 Gene3D G3DSA:1.10.10.10 149 225 1.2E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1019375 68b920e79aa11bca8d4947a985ef45f8 332 Pfam PF01136 Peptidase family U32 75 331 4.3E-65 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MADE_1019375 68b920e79aa11bca8d4947a985ef45f8 332 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 MADE_1015550 8224656ddd31f40f8d5abb9477e0e0b1 186 Pfam PF16036 Chalcone isomerase-like 47 184 1.1E-13 T 13-10-2018 IPR016087 Chalcone isomerase GO:0016872 MADE_1015550 8224656ddd31f40f8d5abb9477e0e0b1 186 Gene3D G3DSA:3.50.70.10 23 168 1.8E-5 T 13-10-2018 IPR016088 Chalcone isomerase, 3-layer sandwich KEGG: 00941+5.5.1.6|MetaCyc: PWY-2002|MetaCyc: PWY-5059|MetaCyc: PWY-6325|MetaCyc: PWY-6787|MetaCyc: PWY-7397|MetaCyc: PWY-7897 MADE_1016140 e4aeabc8899d5962c8aebcc916278673 262 Pfam PF01764 Lipase (class 3) 60 204 3.7E-20 T 13-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 MADE_1016140 e4aeabc8899d5962c8aebcc916278673 262 SUPERFAMILY SSF53474 9 226 5.96E-34 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1016140 e4aeabc8899d5962c8aebcc916278673 262 Gene3D G3DSA:3.40.50.1820 4 239 3.5E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1015740 247243caf49175528d5b8afe124cd646 260 SUPERFAMILY SSF55729 15 237 2.17E-86 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1015740 247243caf49175528d5b8afe124cd646 260 Gene3D G3DSA:2.30.210.20 16 73 3.4E-25 T 13-10-2018 MADE_1015740 247243caf49175528d5b8afe124cd646 260 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 47 223 3.3E-70 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MADE_1015740 247243caf49175528d5b8afe124cd646 260 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 44 234 1.0E-61 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MADE_1015740 247243caf49175528d5b8afe124cd646 260 Gene3D G3DSA:3.40.630.70 74 253 6.7E-62 T 13-10-2018 MADE_1015740 247243caf49175528d5b8afe124cd646 260 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 260 86.17 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 MADE_1009990 9ed1076368913d57da3d59a08c8079bb 61 Pfam PF09791 Oxidoreductase-like protein, N-terminal 3 44 1.6E-11 T 13-10-2018 IPR019180 Oxidoreductase-like, N-terminal MADE_1007805 f0cb2563f8455b6b85391029d6c3b1bf 172 SUPERFAMILY SSF51261 18 161 1.62E-28 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1007805 f0cb2563f8455b6b85391029d6c3b1bf 172 Gene3D G3DSA:2.70.70.10 16 170 7.8E-29 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1007805 f0cb2563f8455b6b85391029d6c3b1bf 172 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 26 147 1.4E-27 T 13-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 MADE_1004425 42165b12f4cad2cb515175bc5f42e3d6 171 SUPERFAMILY SSF52799 19 148 9.84E-12 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like MADE_1004425 42165b12f4cad2cb515175bc5f42e3d6 171 Gene3D G3DSA:3.90.190.10 8 155 7.6E-12 T 13-10-2018 IPR029021 Protein-tyrosine phosphatase-like MADE_1012730 bcb110d62b66caa2235ccd29b90a5436 630 SUPERFAMILY SSF109998 41 243 1.65E-36 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily MADE_1012730 bcb110d62b66caa2235ccd29b90a5436 630 Pfam PF13616 PPIC-type PPIASE domain 267 367 2.4E-30 T 13-10-2018 MADE_1012730 bcb110d62b66caa2235ccd29b90a5436 630 Pfam PF13624 SurA N-terminal domain 1 165 5.9E-48 T 13-10-2018 MADE_1012730 bcb110d62b66caa2235ccd29b90a5436 630 Gene3D G3DSA:1.10.4030.30 40 203 1.7E-18 T 13-10-2018 MADE_1012730 bcb110d62b66caa2235ccd29b90a5436 630 Gene3D G3DSA:3.10.50.40 264 388 8.9E-37 T 13-10-2018 MADE_1012730 bcb110d62b66caa2235ccd29b90a5436 630 SUPERFAMILY SSF54534 265 369 5.76E-30 T 13-10-2018 MADE_000001022740 37d1d877ec98d681b83649e314a17217 621 SUPERFAMILY SSF56300 115 514 5.5E-8 T 13-10-2018 MADE_1001650 8212cac132cbe503a2d3739bc7184146 264 SUPERFAMILY SSF48695 18 260 6.61E-22 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily MADE_1001650 8212cac132cbe503a2d3739bc7184146 264 Pfam PF02085 Class III cytochrome C family 43 105 5.5E-6 T 13-10-2018 IPR020942 Class III cytochrome C GO:0009055|GO:0020037 MADE_1001650 8212cac132cbe503a2d3739bc7184146 264 Gene3D G3DSA:3.90.10.10 174 252 2.6E-5 T 13-10-2018 MADE_1015815 3bdd40d9998b2418667c517da2ba8ae3 308 SUPERFAMILY SSF53807 57 305 1.02E-46 T 13-10-2018 MADE_1015815 3bdd40d9998b2418667c517da2ba8ae3 308 Gene3D G3DSA:3.40.50.1980 64 182 7.8E-34 T 13-10-2018 MADE_1015815 3bdd40d9998b2418667c517da2ba8ae3 308 Pfam PF01497 Periplasmic binding protein 67 268 3.5E-19 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain MADE_1015815 3bdd40d9998b2418667c517da2ba8ae3 308 Gene3D G3DSA:3.40.50.1980 184 308 5.5E-19 T 13-10-2018 MADE_1006165 28a5b066ebdd7bd6c8236fb06645e826 79 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 7 78 3.2E-30 T 13-10-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 MADE_1006165 28a5b066ebdd7bd6c8236fb06645e826 79 Pfam PF06667 Phage shock protein B 7 77 6.0E-34 T 13-10-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 MADE_1009980 c70149c1c2be7e4e595aca186ac32dc7 140 Pfam PF01638 HxlR-like helix-turn-helix 49 138 3.2E-37 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type MADE_1009980 c70149c1c2be7e4e595aca186ac32dc7 140 Gene3D G3DSA:1.10.10.10 34 140 5.0E-42 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1009980 c70149c1c2be7e4e595aca186ac32dc7 140 SUPERFAMILY SSF46785 36 136 2.31E-37 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1006260 c122591996f5b04d96cb48d95a3e4fe0 174 Pfam PF01618 MotA/TolQ/ExbB proton channel family 64 161 5.1E-22 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MADE_1003830 9079e616df922928cf04790745e37457 396 TIGRFAM TIGR00843 benE: benzoate transporter 9 387 4.6E-90 T 13-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MADE_1003830 9079e616df922928cf04790745e37457 396 Pfam PF03594 Benzoate membrane transport protein 3 387 1.2E-116 T 13-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 MADE_1013180 e4c976d2ba3a46253f72376c37d423d2 343 Gene3D G3DSA:3.40.50.300 46 324 2.9E-17 T 13-10-2018 MADE_1013180 e4c976d2ba3a46253f72376c37d423d2 343 Pfam PF13469 Sulfotransferase family 62 292 4.3E-12 T 13-10-2018 MADE_1013180 e4c976d2ba3a46253f72376c37d423d2 343 SUPERFAMILY SSF52540 60 336 1.52E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012170 1c1012a8f9e02aee65bbf723cc9e207c 175 SUPERFAMILY SSF158442 18 165 3.14E-41 T 13-10-2018 IPR023380 DsbB-like superfamily MADE_1012170 1c1012a8f9e02aee65bbf723cc9e207c 175 Pfam PF02600 Disulfide bond formation protein DsbB 15 163 2.3E-41 T 13-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 MADE_1012170 1c1012a8f9e02aee65bbf723cc9e207c 175 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 10 171 19.955 T 13-10-2018 IPR022920 Disulphide bond formation protein DsbB MADE_1012170 1c1012a8f9e02aee65bbf723cc9e207c 175 Gene3D G3DSA:1.20.1550.10 4 174 4.1E-50 T 13-10-2018 IPR023380 DsbB-like superfamily MADE_1012150 43fb26976c699fc17fc72729d590a106 119 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 11 43 5.9E-7 T 13-10-2018 IPR008769 Poly granule associated MADE_1012150 43fb26976c699fc17fc72729d590a106 119 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 38 83 6.2E-7 T 13-10-2018 IPR008769 Poly granule associated MADE_1012150 43fb26976c699fc17fc72729d590a106 119 Gene3D G3DSA:1.20.120.20 1 119 2.7E-5 T 13-10-2018 MADE_1016035 fe97f8f1f2a24d7aa8710cb4346a1f2c 282 SMART SM00244 49 215 1.0E-11 T 13-10-2018 IPR001107 Band 7 domain MADE_1016035 fe97f8f1f2a24d7aa8710cb4346a1f2c 282 SUPERFAMILY SSF117892 83 217 2.62E-12 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily MADE_1016035 fe97f8f1f2a24d7aa8710cb4346a1f2c 282 Gene3D G3DSA:3.30.479.30 80 217 3.5E-9 T 13-10-2018 MADE_1016035 fe97f8f1f2a24d7aa8710cb4346a1f2c 282 Pfam PF01145 SPFH domain / Band 7 family 53 225 1.4E-25 T 13-10-2018 IPR001107 Band 7 domain MADE_1006130 e5b397ecb28235596b2a8f281e286511 267 SUPERFAMILY SSF52540 4 252 2.51E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006130 e5b397ecb28235596b2a8f281e286511 267 SMART SM00382 37 231 1.1E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1006130 e5b397ecb28235596b2a8f281e286511 267 Gene3D G3DSA:3.40.50.300 2 266 1.4E-63 T 13-10-2018 MADE_1006130 e5b397ecb28235596b2a8f281e286511 267 Pfam PF00005 ABC transporter 30 182 1.2E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1002960 7a3bb43866f616322b6a6e34c7ee028d 458 Pfam PF03553 Na+/H+ antiporter family 175 452 1.0E-46 T 13-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MADE_1012175 5148fd1625722da7ddf745670203d5a7 184 Gene3D G3DSA:3.40.630.30 18 183 4.4E-31 T 13-10-2018 MADE_1012175 5148fd1625722da7ddf745670203d5a7 184 Pfam PF13302 Acetyltransferase (GNAT) domain 30 159 6.4E-18 T 13-10-2018 IPR000182 GNAT domain MADE_1012175 5148fd1625722da7ddf745670203d5a7 184 SUPERFAMILY SSF55729 16 178 1.78E-30 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_000001023470 4ece0d6f6dd2228def40df3b267b2704 390 Pfam PF13412 Winged helix-turn-helix DNA-binding 23 68 1.5E-8 T 13-10-2018 MADE_000001023470 4ece0d6f6dd2228def40df3b267b2704 390 Gene3D G3DSA:1.10.10.10 20 88 1.5E-12 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_000001023470 4ece0d6f6dd2228def40df3b267b2704 390 Gene3D G3DSA:3.30.420.40 94 216 9.4E-31 T 13-10-2018 MADE_000001023470 4ece0d6f6dd2228def40df3b267b2704 390 SUPERFAMILY SSF53067 94 387 2.04E-29 T 13-10-2018 MADE_000001023470 4ece0d6f6dd2228def40df3b267b2704 390 Gene3D G3DSA:3.30.420.40 219 353 9.4E-31 T 13-10-2018 MADE_000001023470 4ece0d6f6dd2228def40df3b267b2704 390 SUPERFAMILY SSF46785 21 87 6.39E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_000001023470 4ece0d6f6dd2228def40df3b267b2704 390 Pfam PF00480 ROK family 94 255 1.0E-16 T 13-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 MADE_1002340 396e43ba95377572d3292e353af92ad6 604 Pfam PF02254 TrkA-N domain 400 500 1.5E-6 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 MADE_1002340 396e43ba95377572d3292e353af92ad6 604 Gene3D G3DSA:1.20.1530.20 2 394 3.1E-17 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily MADE_1002340 396e43ba95377572d3292e353af92ad6 604 Gene3D G3DSA:3.40.50.720 398 516 4.3E-10 T 13-10-2018 MADE_1002340 396e43ba95377572d3292e353af92ad6 604 Pfam PF00999 Sodium/hydrogen exchanger family 10 385 2.9E-35 T 13-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 MADE_1002340 396e43ba95377572d3292e353af92ad6 604 SUPERFAMILY SSF51735 400 502 2.36E-9 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1001465 74913c5b13e3139301239318a98e2704 295 Pfam PF02481 DNA recombination-mediator protein A 76 284 1.7E-59 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 MADE_1001465 74913c5b13e3139301239318a98e2704 295 SUPERFAMILY SSF102405 84 293 4.32E-32 T 13-10-2018 MADE_1001465 74913c5b13e3139301239318a98e2704 295 Gene3D G3DSA:3.40.50.450 30 294 9.3E-63 T 13-10-2018 MADE_1005840 48f57427285d9dc54b32ec5ef4f94e9b 89 SUPERFAMILY SSF46689 1 70 2.51E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1005840 48f57427285d9dc54b32ec5ef4f94e9b 89 Pfam PF01527 Transposase 2 71 8.9E-24 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 MADE_1009795 0450778cfe6f14afa5e3e314b3f90277 265 Pfam PF13566 Domain of unknown function (DUF4130 81 239 3.8E-38 T 13-10-2018 IPR025404 Domain of unknown function DUF4130 MADE_1009795 0450778cfe6f14afa5e3e314b3f90277 265 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 12 240 1.2E-65 T 13-10-2018 IPR023875 DNA metabolism protein, putative MADE_1005375 640b92c9ba51223ce09434864eeea594 256 Gene3D G3DSA:2.160.10.10 1 186 8.3E-54 T 13-10-2018 MADE_1005375 640b92c9ba51223ce09434864eeea594 256 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 2 254 3.9E-101 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MADE_1005375 640b92c9ba51223ce09434864eeea594 256 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 174 255 1.6E-26 T 13-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 MADE_1005375 640b92c9ba51223ce09434864eeea594 256 PIRSF PIRSF000456 1 256 6.3E-103 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MADE_1005375 640b92c9ba51223ce09434864eeea594 256 SUPERFAMILY SSF51161 2 256 7.92E-78 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily MADE_1005375 640b92c9ba51223ce09434864eeea594 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 46 7.7E-11 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1005375 640b92c9ba51223ce09434864eeea594 256 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 137 1.4E-4 T 13-10-2018 IPR001451 Hexapeptide repeat MADE_1005375 640b92c9ba51223ce09434864eeea594 256 Gene3D G3DSA:1.20.1180.10 191 256 2.7E-23 T 13-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 MADE_1005375 640b92c9ba51223ce09434864eeea594 256 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 256 43.132 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 MADE_000001021105 4ca6510cf0747da97b076e5292caf2c2 101 Gene3D G3DSA:3.30.750.24 2 101 9.1E-19 T 13-10-2018 IPR036513 STAS domain superfamily MADE_000001021105 4ca6510cf0747da97b076e5292caf2c2 101 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 100 1.2E-15 T 13-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 MADE_000001021105 4ca6510cf0747da97b076e5292caf2c2 101 Pfam PF13466 STAS domain 21 95 5.0E-11 T 13-10-2018 IPR002645 STAS domain MADE_000001021105 4ca6510cf0747da97b076e5292caf2c2 101 SUPERFAMILY SSF52091 8 100 2.35E-19 T 13-10-2018 IPR036513 STAS domain superfamily MADE_1015350 8644dece379879b2d44222217c01167a 232 Pfam PF01168 Alanine racemase, N-terminal domain 19 227 3.4E-28 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 MADE_1015350 8644dece379879b2d44222217c01167a 232 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 6 226 32.863 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MADE_1015350 8644dece379879b2d44222217c01167a 232 PIRSF PIRSF004848 1 232 1.4E-77 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MADE_1015350 8644dece379879b2d44222217c01167a 232 Gene3D G3DSA:3.20.20.10 1 232 1.3E-83 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1015350 8644dece379879b2d44222217c01167a 232 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 227 6.0E-82 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MADE_1015350 8644dece379879b2d44222217c01167a 232 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 77 91 - T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 MADE_1015350 8644dece379879b2d44222217c01167a 232 SUPERFAMILY SSF51419 1 225 6.41E-81 T 13-10-2018 IPR029066 PLP-binding barrel MADE_1002625 da8c7cb2e523a5d1472ce45a513e8dab 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 4.3E-13 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1002625 da8c7cb2e523a5d1472ce45a513e8dab 200 SUPERFAMILY SSF46689 10 77 2.82E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1002625 da8c7cb2e523a5d1472ce45a513e8dab 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.8E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1002625 da8c7cb2e523a5d1472ce45a513e8dab 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.8E-7 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1002625 da8c7cb2e523a5d1472ce45a513e8dab 200 Gene3D G3DSA:1.10.357.10 6 195 1.7E-32 T 13-10-2018 MADE_1002625 da8c7cb2e523a5d1472ce45a513e8dab 200 Pfam PF13305 WHG domain 95 167 8.8E-8 T 13-10-2018 IPR025996 WHG domain MADE_1002625 da8c7cb2e523a5d1472ce45a513e8dab 200 SUPERFAMILY SSF48498 86 171 1.96E-11 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MADE_1005735 5e225acf1a571f0bcaebde9cc118c304 226 PRINTS PR01008 Flagellar L-ring protein signature 165 181 6.1E-24 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MADE_1005735 5e225acf1a571f0bcaebde9cc118c304 226 PRINTS PR01008 Flagellar L-ring protein signature 139 154 6.1E-24 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MADE_1005735 5e225acf1a571f0bcaebde9cc118c304 226 PRINTS PR01008 Flagellar L-ring protein signature 186 200 6.1E-24 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MADE_1005735 5e225acf1a571f0bcaebde9cc118c304 226 PRINTS PR01008 Flagellar L-ring protein signature 66 78 6.1E-24 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MADE_1005735 5e225acf1a571f0bcaebde9cc118c304 226 PRINTS PR01008 Flagellar L-ring protein signature 202 216 6.1E-24 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MADE_1005735 5e225acf1a571f0bcaebde9cc118c304 226 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 223 27.144 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MADE_1005735 5e225acf1a571f0bcaebde9cc118c304 226 Pfam PF02107 Flagellar L-ring protein 45 225 6.8E-62 T 13-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 MADE_1013020 7dcfbf81b130c46fe32b2e3ea176ec00 233 PIRSF PIRSF028137 2 233 2.0E-74 T 13-10-2018 IPR016870 Uncharacterised conserved protein UCP028137, membrane MADE_000001021770 78e16f92461275f1327602f9b0f2ea90 183 SUPERFAMILY SSF55469 1 181 2.36E-35 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_000001021770 78e16f92461275f1327602f9b0f2ea90 183 Pfam PF00881 Nitroreductase family 9 161 3.4E-21 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 MADE_000001021770 78e16f92461275f1327602f9b0f2ea90 183 Gene3D G3DSA:3.40.109.10 1 180 1.6E-37 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 MADE_000001021770 78e16f92461275f1327602f9b0f2ea90 183 PIRSF PIRSF000232 1 183 3.5E-57 T 13-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like MADE_1001850 4c01b4b6f0b3dcbe254d6cabd72b27d8 242 Pfam PF08019 Domain of unknown function (DUF1705) 59 208 1.4E-33 T 13-10-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 MADE_1000590 cd979e937a475ce7edab461aa290609b 372 Gene3D G3DSA:3.40.50.620 1 161 1.0E-19 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1000590 cd979e937a475ce7edab461aa290609b 372 SUPERFAMILY SSF52402 9 137 1.83E-14 T 13-10-2018 MADE_1000590 cd979e937a475ce7edab461aa290609b 372 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 9 136 2.6E-7 T 13-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 MADE_1004610 94f8299b4f3d6cd498b0c76499fa85d9 108 Pfam PF12514 Protein of unknown function (DUF3718) 40 99 1.7E-20 T 13-10-2018 IPR022193 Protein of unknown function DUF3718 MADE_1003560 c67f3084c566c6feaa7fbec11cdd4248 267 Gene3D G3DSA:3.60.21.10 1 267 2.0E-47 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like MADE_1003560 c67f3084c566c6feaa7fbec11cdd4248 267 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 224 265 0.003 T 13-10-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 MADE_1003560 c67f3084c566c6feaa7fbec11cdd4248 267 SUPERFAMILY SSF56300 2 265 1.52E-37 T 13-10-2018 MADE_1003560 c67f3084c566c6feaa7fbec11cdd4248 267 Pfam PF00149 Calcineurin-like phosphoesterase 3 210 8.6E-13 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MADE_1000790 686f2a06f37ebe601611417503a328d8 258 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 8 256 36.202 T 13-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MADE_1000790 686f2a06f37ebe601611417503a328d8 258 Pfam PF04445 Putative SAM-dependent methyltransferase 37 254 7.4E-88 T 13-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 MADE_1000790 686f2a06f37ebe601611417503a328d8 258 Gene3D G3DSA:3.40.50.150 67 257 1.7E-71 T 13-10-2018 MADE_1000790 686f2a06f37ebe601611417503a328d8 258 SUPERFAMILY SSF53335 14 256 2.01E-64 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1000780 74d49c6362689fa295e7bfd820b0ec48 235 SUPERFAMILY SSF75217 4 183 3.53E-49 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases MADE_1000780 74d49c6362689fa295e7bfd820b0ec48 235 Gene3D G3DSA:3.40.1280.10 1 200 2.0E-62 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal MADE_1000780 74d49c6362689fa295e7bfd820b0ec48 235 Pfam PF12105 SpoU, rRNA methylase, C-terminal 162 215 3.3E-20 T 13-10-2018 IPR022724 RNA methyltransferase, SpoU/TrmH type, C-terminal GO:0009020 MADE_1000780 74d49c6362689fa295e7bfd820b0ec48 235 Pfam PF00588 SpoU rRNA Methylase family 20 158 3.9E-34 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 MADE_1000780 74d49c6362689fa295e7bfd820b0ec48 235 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 2 194 36.257 T 13-10-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 SUPERFAMILY SSF46894 127 226 1.45E-31 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 SUPERFAMILY SSF52172 2 129 1.01E-42 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 Gene3D G3DSA:3.40.50.2300 1 127 3.4E-38 T 13-10-2018 MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 Pfam PF00072 Response regulator receiver domain 5 117 5.6E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 SMART SM00862 150 225 1.0E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 5.6E-27 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 6.8E-111 T 13-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 Gene3D G3DSA:1.10.10.10 128 229 2.1E-38 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1003850 1022b4f80128c20f747f18f4a9beecf6 229 SMART SM00448 3 116 1.7E-43 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1004400 880e258763b57d0773bb315501dc84e3 268 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 22 268 2.1E-116 T 13-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 MADE_1004400 880e258763b57d0773bb315501dc84e3 268 Pfam PF00005 ABC transporter 37 193 5.5E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004400 880e258763b57d0773bb315501dc84e3 268 SUPERFAMILY SSF52540 19 255 1.22E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004400 880e258763b57d0773bb315501dc84e3 268 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1004400 880e258763b57d0773bb315501dc84e3 268 SMART SM00382 46 240 2.0E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004400 880e258763b57d0773bb315501dc84e3 268 Gene3D G3DSA:3.40.50.300 17 265 1.0E-66 T 13-10-2018 MADE_1015915 e6c2939f8debb658c1e945ad1bd42f25 269 Pfam PF13614 AAA domain 3 158 5.2E-21 T 13-10-2018 IPR025669 AAA domain MADE_1015915 e6c2939f8debb658c1e945ad1bd42f25 269 SUPERFAMILY SSF52540 1 267 5.25E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015915 e6c2939f8debb658c1e945ad1bd42f25 269 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 265 1.3E-112 T 13-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 MADE_1015915 e6c2939f8debb658c1e945ad1bd42f25 269 Gene3D G3DSA:3.40.50.300 1 258 7.7E-71 T 13-10-2018 MADE_1015915 e6c2939f8debb658c1e945ad1bd42f25 269 PIRSF PIRSF003092 1 269 3.0E-94 T 13-10-2018 IPR025501 ATP binding protein MinD MADE_000001021920 a7dd65f2508fed835b6a7af1514b737a 52 Pfam PF01679 Proteolipid membrane potential modulator 2 49 5.2E-24 T 13-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 MADE_000001021920 a7dd65f2508fed835b6a7af1514b737a 52 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 7 22 - T 13-10-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 MADE_1003025 4ef91f2373f1af4ef8119ac8bda7d21d 109 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 109 3.5E-37 T 13-10-2018 IPR004624 PhnA protein MADE_1003025 4ef91f2373f1af4ef8119ac8bda7d21d 109 Gene3D G3DSA:2.30.30.40 40 109 1.9E-24 T 13-10-2018 MADE_1003025 4ef91f2373f1af4ef8119ac8bda7d21d 109 SUPERFAMILY SSF82057 36 109 3.02E-22 T 13-10-2018 MADE_1003025 4ef91f2373f1af4ef8119ac8bda7d21d 109 Pfam PF08274 PhnA Zinc-Ribbon 2 30 8.6E-15 T 13-10-2018 IPR013987 PhnA protein, N-terminal MADE_1003025 4ef91f2373f1af4ef8119ac8bda7d21d 109 Pfam PF03831 PhnA domain 42 109 1.3E-24 T 13-10-2018 IPR013988 PhnA protein, C-terminal MADE_1003025 4ef91f2373f1af4ef8119ac8bda7d21d 109 Gene3D G3DSA:2.20.25.10 1 39 2.5E-19 T 13-10-2018 MADE_1003025 4ef91f2373f1af4ef8119ac8bda7d21d 109 SUPERFAMILY SSF57783 1 37 5.1E-15 T 13-10-2018 MADE_1019890 16fdb2e9eebd0a3e3bea77ca5da28e90 193 Gene3D G3DSA:3.90.950.10 8 193 3.2E-50 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_1019890 16fdb2e9eebd0a3e3bea77ca5da28e90 193 Pfam PF01931 Protein of unknown function DUF84 21 185 1.9E-51 T 13-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 MADE_1019890 16fdb2e9eebd0a3e3bea77ca5da28e90 193 SUPERFAMILY SSF52972 17 191 2.14E-50 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like MADE_000001022305 4bd8cdf54bd5f52682b4c67a49ca7520 370 Gene3D G3DSA:3.20.20.105 1 364 5.7E-170 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MADE_000001022305 4bd8cdf54bd5f52682b4c67a49ca7520 370 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 365 1.7E-175 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MADE_000001022305 4bd8cdf54bd5f52682b4c67a49ca7520 370 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 362 57.002 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MADE_000001022305 4bd8cdf54bd5f52682b4c67a49ca7520 370 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 359 3.2E-93 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MADE_000001022305 4bd8cdf54bd5f52682b4c67a49ca7520 370 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 364 3.8E-168 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MADE_000001022305 4bd8cdf54bd5f52682b4c67a49ca7520 370 SUPERFAMILY SSF51713 1 362 1.26E-163 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 MADE_1003045 bb45e7ead6b19c005349c22e7353efa4 73 Pfam PF05534 HicB family 3 33 3.2E-6 T 13-10-2018 IPR008651 Uncharacterised protein family HicB MADE_1003045 bb45e7ead6b19c005349c22e7353efa4 73 SUPERFAMILY SSF47598 1 45 2.03E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1009330 0829dbe5987880d91e2d8ea805dc7b20 91 Gene3D G3DSA:3.40.630.10 1 90 3.6E-15 T 13-10-2018 MADE_1009330 0829dbe5987880d91e2d8ea805dc7b20 91 SUPERFAMILY SSF53187 3 78 2.51E-5 T 13-10-2018 MADE_1009330 0829dbe5987880d91e2d8ea805dc7b20 91 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 32 83 9.5E-5 T 13-10-2018 IPR019217 Protein of unknown function DUF2118 MADE_1013085 1c5fe1beee604f1204798090402bd9e1 360 Pfam PF14907 Uncharacterised nucleotidyltransferase 29 275 2.9E-36 T 13-10-2018 IPR039498 Uncharacterised nucleotidyltransferase MADE_1016365 5060b54b6d9abb55deac7022ac8b1318 499 Gene3D G3DSA:3.40.605.10 23 459 6.4E-143 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 MADE_1016365 5060b54b6d9abb55deac7022ac8b1318 499 Pfam PF00171 Aldehyde dehydrogenase family 15 478 6.7E-134 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 MADE_1016365 5060b54b6d9abb55deac7022ac8b1318 499 SUPERFAMILY SSF53720 5 483 5.76E-141 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 MADE_1016365 5060b54b6d9abb55deac7022ac8b1318 499 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 482 2.3E-188 T 13-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 MADE_1016365 5060b54b6d9abb55deac7022ac8b1318 499 Gene3D G3DSA:3.40.309.10 249 451 6.4E-143 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 MADE_000001022315 f1cb3eee843efad03c7b9b7b59622d8e 415 Pfam PF04219 Protein of unknown function, DUF 310 396 1.7E-32 T 13-10-2018 IPR007335 Protein of unknown function DUF413 MADE_000001022315 f1cb3eee843efad03c7b9b7b59622d8e 415 Pfam PF13007 Transposase C of IS166 homeodomain 27 86 3.7E-10 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain MADE_000001022315 f1cb3eee843efad03c7b9b7b59622d8e 415 Pfam PF03050 Transposase IS66 family 172 298 1.1E-25 T 13-10-2018 IPR004291 Transposase, IS66 MADE_000001021115 f04602a2ce966dfa386224effb526338 147 SUPERFAMILY SSF158682 14 140 1.18E-22 T 13-10-2018 IPR029024 TerB-like MADE_000001021115 f04602a2ce966dfa386224effb526338 147 Gene3D G3DSA:1.10.3680.10 3 136 1.1E-15 T 13-10-2018 IPR029024 TerB-like MADE_000001021115 f04602a2ce966dfa386224effb526338 147 Pfam PF05099 Tellurite resistance protein TerB 13 139 1.1E-33 T 13-10-2018 IPR007791 Co-chaperone DjlA, N-terminal MADE_1007020 e54d9b09af1669ee797446742897d793 792 Pfam PF00593 TonB dependent receptor 289 791 1.5E-39 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel MADE_1007020 e54d9b09af1669ee797446742897d793 792 Gene3D G3DSA:2.40.170.20 76 792 7.2E-139 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily MADE_1007020 e54d9b09af1669ee797446742897d793 792 SUPERFAMILY SSF56935 65 792 5.9E-111 T 13-10-2018 MADE_1007020 e54d9b09af1669ee797446742897d793 792 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 193 6.9E-15 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1019880 0e9f86f92a2fb6dcd2ffdf89d7619b7a 477 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 473 4.3E-63 T 13-10-2018 IPR010352 Protein of unknown function DUF945 MADE_000001020755 cdbf7b7f2f68058c68417f1a5d95a1a1 99 Gene3D G3DSA:3.30.200.70 11 85 1.2E-30 T 13-10-2018 MADE_000001020755 cdbf7b7f2f68058c68417f1a5d95a1a1 99 SUPERFAMILY SSF56112 4 88 6.73E-17 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_000001020755 cdbf7b7f2f68058c68417f1a5d95a1a1 99 Gene3D G3DSA:1.10.510.10 58 84 1.2E-30 T 13-10-2018 MADE_000001020755 cdbf7b7f2f68058c68417f1a5d95a1a1 99 Pfam PF01636 Phosphotransferase enzyme family 34 86 1.5E-7 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase MADE_000001022980 d67c8adba746a5abbdc7ae044cee008d 400 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 395 4.0E-174 T 13-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 MADE_000001022980 d67c8adba746a5abbdc7ae044cee008d 400 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 399 35.717 T 13-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 MADE_000001022980 d67c8adba746a5abbdc7ae044cee008d 400 PIRSF PIRSF016055 1 400 2.8E-193 T 13-10-2018 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0010181|GO:0016021|GO:0016655|GO:0022904 MADE_000001022980 d67c8adba746a5abbdc7ae044cee008d 400 Pfam PF03116 NQR2, RnfD, RnfE family 42 392 2.0E-106 T 13-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 MADE_1009660 28655833d01d52f0b36d51ed1a3d1ed9 290 Gene3D G3DSA:3.40.50.150 1 286 1.1E-58 T 13-10-2018 MADE_1009660 28655833d01d52f0b36d51ed1a3d1ed9 290 SUPERFAMILY SSF53335 1 256 3.28E-24 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1009660 28655833d01d52f0b36d51ed1a3d1ed9 290 PIRSF PIRSF018249 1 286 4.9E-67 T 13-10-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 MADE_1009660 28655833d01d52f0b36d51ed1a3d1ed9 290 Pfam PF13847 Methyltransferase domain 100 213 3.4E-7 T 13-10-2018 IPR025714 Methyltransferase domain MADE_000001022260 55c25e1463fd4f20833912935aa5ecfc 283 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 259 282 1.2E-4 T 13-10-2018 IPR013424 PEP-CTERM protein-sorting domain MADE_1018530 60632fe1825628b6b1cb29df976edf87 295 Pfam PF01963 TraB family 33 294 1.3E-67 T 13-10-2018 IPR002816 Pheromone shutdown, TraB MADE_000001022115 6172c338499b29519a638acad67330c5 430 PIRSF PIRSF000505 4 430 9.1E-157 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MADE_000001022115 6172c338499b29519a638acad67330c5 430 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 17 427 8.7E-147 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MADE_000001022115 6172c338499b29519a638acad67330c5 430 Gene3D G3DSA:3.65.10.10 245 421 2.5E-155 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MADE_000001022115 6172c338499b29519a638acad67330c5 430 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 422 2.8E-153 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 MADE_000001022115 6172c338499b29519a638acad67330c5 430 SUPERFAMILY SSF55205 4 427 6.54E-141 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 MADE_000001022115 6172c338499b29519a638acad67330c5 430 ProSitePatterns PS00104 EPSP synthase signature 1. 93 107 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MADE_000001022115 6172c338499b29519a638acad67330c5 430 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MADE_000001022115 6172c338499b29519a638acad67330c5 430 Gene3D G3DSA:3.65.10.10 23 227 2.5E-155 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 MADE_000001022115 6172c338499b29519a638acad67330c5 430 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 430 35.458 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 MADE_1007105 ee3e911c6ef5bdf36afcbebd74ee0258 179 SUPERFAMILY SSF55811 4 176 2.98E-37 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_1007105 ee3e911c6ef5bdf36afcbebd74ee0258 179 Gene3D G3DSA:3.90.79.10 2 176 1.7E-40 T 13-10-2018 MADE_1001455 47490883a0b770946f16730fefe66891 701 Pfam PF13148 Protein of unknown function (DUF3987) 233 620 4.1E-53 T 13-10-2018 IPR025048 Protein of unknown function DUF3987) MADE_1000430 014c1e45c551318422c2bf7a93074364 105 Gene3D G3DSA:2.170.130.10 14 94 2.5E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1000430 014c1e45c551318422c2bf7a93074364 105 Pfam PF07715 TonB-dependent Receptor Plug Domain 17 91 2.6E-13 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1000430 014c1e45c551318422c2bf7a93074364 105 SUPERFAMILY SSF56935 18 91 4.58E-15 T 13-10-2018 MADE_1004460 1e7c5d3809195fb07254ae5473a71983 430 Pfam PF12576 Protein of unknown function (DUF3754) 157 310 8.8E-37 T 13-10-2018 IPR022227 Protein of unknown function DUF3754 MADE_1020240 43bcf6ac66f8f708f55c16b008b5f615 194 PIRSF PIRSF029557 2 194 1.6E-58 T 13-10-2018 IPR010707 Protein of unknown function DUF1285 MADE_1020240 43bcf6ac66f8f708f55c16b008b5f615 194 Gene3D G3DSA:3.10.540.10 2 86 7.9E-33 T 13-10-2018 MADE_1020240 43bcf6ac66f8f708f55c16b008b5f615 194 Gene3D G3DSA:2.30.270.10 87 163 9.9E-14 T 13-10-2018 IPR023361 DUF1285, beta-roll domain superfamily MADE_1020240 43bcf6ac66f8f708f55c16b008b5f615 194 Pfam PF06938 Protein of unknown function (DUF1285) 36 187 1.1E-47 T 13-10-2018 IPR010707 Protein of unknown function DUF1285 MADE_000001022760 88e7798dd835b1630cf8dc20bcf95ac8 815 SUPERFAMILY SSF48452 161 387 2.01E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022760 88e7798dd835b1630cf8dc20bcf95ac8 815 Gene3D G3DSA:1.25.40.10 216 390 1.2E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_000001022760 88e7798dd835b1630cf8dc20bcf95ac8 815 Pfam PF05420 Cellulose synthase operon protein C C-terminus (BCSC_C) 549 790 2.8E-37 T 13-10-2018 IPR008410 Cellulose synthase operon C, C-terminal GO:0019867|GO:0030244 MADE_1013710 7ad0ba7f846e5397aa5ffe64cf24083e 721 SUPERFAMILY SSF50494 48 713 4.11E-21 T 13-10-2018 IPR009003 Peptidase S1, PA clan MADE_1013710 7ad0ba7f846e5397aa5ffe64cf24083e 721 Pfam PF10459 Peptidase S46 22 719 4.4E-260 T 13-10-2018 IPR019500 Peptidase S46 GO:0008239|GO:0070009 MADE_000001023225 fe630f960de0e603b4b6c907f0065265 350 Gene3D G3DSA:2.40.50.100 65 222 1.7E-27 T 13-10-2018 MADE_000001023225 fe630f960de0e603b4b6c907f0065265 350 SUPERFAMILY SSF111369 68 172 3.53E-9 T 13-10-2018 MADE_000001023225 fe630f960de0e603b4b6c907f0065265 350 Pfam PF13437 HlyD family secretion protein 188 247 5.5E-5 T 13-10-2018 MADE_000001023225 fe630f960de0e603b4b6c907f0065265 350 Gene3D G3DSA:1.10.287.470 99 185 1.7E-27 T 13-10-2018 MADE_000001023225 fe630f960de0e603b4b6c907f0065265 350 Pfam PF13533 Biotin-lipoyl like 66 111 1.1E-8 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain MADE_000001023225 fe630f960de0e603b4b6c907f0065265 350 Gene3D G3DSA:2.40.30.170 223 279 1.7E-27 T 13-10-2018 MADE_000001023490 66c1f09f327b9323797d82332d60cf06 329 SUPERFAMILY SSF158855 48 328 5.89E-56 T 13-10-2018 MADE_000001023490 66c1f09f327b9323797d82332d60cf06 329 Pfam PF03280 Proteobacterial lipase chaperone protein 133 319 7.4E-37 T 13-10-2018 IPR004961 Lipase chaperone GO:0006457|GO:0016020|GO:0051082 MADE_1008380 9156e7846f174a8d6c06bd28008e4341 281 Gene3D G3DSA:1.10.3210.10 1 269 2.1E-56 T 13-10-2018 MADE_1008380 9156e7846f174a8d6c06bd28008e4341 281 Pfam PF08668 HDOD domain 15 204 4.0E-49 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD MADE_1008380 9156e7846f174a8d6c06bd28008e4341 281 SUPERFAMILY SSF109604 3 258 3.73E-54 T 13-10-2018 MADE_1006235 446e0b68cd6e5c920de2d745d6283608 330 Gene3D G3DSA:2.60.120.330 107 306 2.6E-36 T 13-10-2018 IPR027443 Isopenicillin N synthase-like MADE_1006235 446e0b68cd6e5c920de2d745d6283608 330 SUPERFAMILY SSF51197 172 299 6.32E-14 T 13-10-2018 MADE_1006235 446e0b68cd6e5c920de2d745d6283608 330 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 167 294 1.2E-27 T 13-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 MADE_1006050 b1695050ab47841cfa5d9b8766068e4f 102 Hamap MF_01537 Pyrimidine/purine nucleoside phosphorylase [ppnP]. 10 102 24.214 T 13-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 MADE_1006050 b1695050ab47841cfa5d9b8766068e4f 102 Pfam PF06865 Protein of unknown function (DUF1255) 12 101 4.3E-34 T 13-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 MADE_1006050 b1695050ab47841cfa5d9b8766068e4f 102 Gene3D G3DSA:2.60.120.10 9 102 2.4E-34 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1006050 b1695050ab47841cfa5d9b8766068e4f 102 SUPERFAMILY SSF51182 11 101 8.91E-34 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1013205 5dde11a66b9071c83882861d6edc6ed8 354 SUPERFAMILY SSF53756 35 338 5.73E-16 T 13-10-2018 MADE_1013205 5dde11a66b9071c83882861d6edc6ed8 354 Gene3D G3DSA:3.40.50.2000 148 329 5.2E-13 T 13-10-2018 MADE_1013205 5dde11a66b9071c83882861d6edc6ed8 354 Pfam PF13692 Glycosyl transferases group 1 176 311 2.7E-17 T 13-10-2018 MADE_1013140 77c6f09dd61362607d4dee3b2f1007ad 362 SUPERFAMILY SSF55729 163 328 2.07E-16 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1013140 77c6f09dd61362607d4dee3b2f1007ad 362 Pfam PF13480 Acetyltransferase (GNAT) domain 171 319 6.5E-16 T 13-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 MADE_1013140 77c6f09dd61362607d4dee3b2f1007ad 362 Gene3D G3DSA:3.40.630.30 136 330 3.4E-5 T 13-10-2018 MADE_1000940 3e37dab86d426b99309ce2e935c43bd9 440 Pfam PF11737 Protein of unknown function (DUF3300) 39 270 3.8E-77 T 13-10-2018 IPR021728 Protein of unknown function DUF3300 MADE_1000245 9d5f389ab0d7c281c89f01c2d9f2d5d7 229 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 17 215 3.9E-42 T 13-10-2018 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB MADE_1000245 9d5f389ab0d7c281c89f01c2d9f2d5d7 229 SUPERFAMILY SSF159270 26 219 4.84E-41 T 13-10-2018 IPR023373 YmcC-like superfamily MADE_1000245 9d5f389ab0d7c281c89f01c2d9f2d5d7 229 Gene3D G3DSA:2.40.360.10 21 225 3.8E-41 T 13-10-2018 IPR023373 YmcC-like superfamily MADE_1013120 2f2ee5b87dff23b892cb40b284c31e31 77 Pfam PF05717 IS66 Orf2 like protein 9 72 4.7E-19 T 13-10-2018 IPR008878 Transposase IS66, Orf2 MADE_1009095 933bf8301fe55f3301a9590d2831f9af 55 Gene3D G3DSA:3.40.570.10 1 55 6.5E-7 T 13-10-2018 MADE_1008110 165f009daf311ab5faef8d31ce82b5fc 401 Pfam PF10082 Putative beta-barrel porin 2 25 399 3.2E-32 T 13-10-2018 IPR018759 Putative beta-barrel porin 2 MADE_1007845 ea0997bf2e591400d7a7e185344e5ee8 346 Pfam PF13280 WYL domain 157 329 2.7E-13 T 13-10-2018 IPR026881 WYL domain MADE_1019360 86e7082c7bb71478bfc9adb702315515 253 Pfam PF00899 ThiF family 12 245 1.2E-63 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MADE_1019360 86e7082c7bb71478bfc9adb702315515 253 SUPERFAMILY SSF69572 4 248 9.55E-84 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MADE_1019360 86e7082c7bb71478bfc9adb702315515 253 Gene3D G3DSA:3.40.50.720 4 252 1.1E-85 T 13-10-2018 MADE_1001145 f5b4db5c99a51181457ff14dd74ae33f 520 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 39 437 2.8E-106 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_1001145 f5b4db5c99a51181457ff14dd74ae33f 520 Gene3D G3DSA:1.20.1730.10 27 520 7.8E-165 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily MADE_1001145 f5b4db5c99a51181457ff14dd74ae33f 520 Pfam PF00474 Sodium:solute symporter family 39 438 1.1E-68 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 MADE_1005605 307311d62e4c2fd9a33460e924167232 76 ProDom PD007968 PLASMID MERE URF-1 RESISTANCE MERCURY MERCURIC DELTA URF1 PRECURSOR TNIB 18 76 1.0E-20 T 13-10-2018 IPR007746 Broad mercury transporter MerE GO:0015097|GO:0015694|GO:0016020 MADE_1005605 307311d62e4c2fd9a33460e924167232 76 Pfam PF05052 MerE protein 1 75 2.3E-46 T 13-10-2018 IPR007746 Broad mercury transporter MerE GO:0015097|GO:0015694|GO:0016020 MADE_1010415 814296885f4abc4d92aa7a7e7b7c2c55 201 SUPERFAMILY SSF46626 17 197 6.5E-31 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1010415 814296885f4abc4d92aa7a7e7b7c2c55 201 Gene3D G3DSA:1.10.760.10 42 201 5.5E-76 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1010415 814296885f4abc4d92aa7a7e7b7c2c55 201 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 5 199 1.6E-84 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MADE_1010415 814296885f4abc4d92aa7a7e7b7c2c55 201 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 5 182 9.7E-84 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO MADE_000001021075 42bf7a4743af0b00054d25afe8636dbc 238 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 218 3.6E-25 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 MADE_000001021075 42bf7a4743af0b00054d25afe8636dbc 238 SUPERFAMILY SSF52096 5 217 1.81E-41 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily MADE_000001021075 42bf7a4743af0b00054d25afe8636dbc 238 Gene3D G3DSA:3.90.226.10 3 229 4.4E-43 T 13-10-2018 MADE_1001805 8d1ec3e41f65931a46701f7b674ad428 426 Gene3D G3DSA:1.20.1600.10 18 420 2.9E-37 T 13-10-2018 MADE_1001805 8d1ec3e41f65931a46701f7b674ad428 426 SUPERFAMILY SSF56954 5 415 6.41E-50 T 13-10-2018 MADE_1001805 8d1ec3e41f65931a46701f7b674ad428 426 Pfam PF02321 Outer membrane efflux protein 241 414 2.0E-14 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1001805 8d1ec3e41f65931a46701f7b674ad428 426 Pfam PF02321 Outer membrane efflux protein 35 211 2.0E-9 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1003365 7cdc9be9bf40b94074ac2d59a1543b6b 192 Pfam PF09335 SNARE associated Golgi protein 53 157 9.7E-14 T 13-10-2018 IPR032816 SNARE associated Golgi protein MADE_1019870 66443bce335ea82599e4d6cda1b93187 159 Pfam PF04612 Type II secretion system (T2SS), protein M 2 157 1.8E-44 T 13-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 MADE_1019870 66443bce335ea82599e4d6cda1b93187 159 Gene3D G3DSA:3.30.1360.100 82 159 5.4E-24 T 13-10-2018 MADE_1019870 66443bce335ea82599e4d6cda1b93187 159 SUPERFAMILY SSF103054 82 157 2.48E-22 T 13-10-2018 IPR023229 Type II secretion system protein M, periplasmic domain superfamily MADE_1019870 66443bce335ea82599e4d6cda1b93187 159 PIRSF PIRSF006291 1 159 7.1E-48 T 13-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 MADE_1019215 3a11660bf3e2bdd54333b3c07b98b2ad 451 SUPERFAMILY SSF56935 26 451 2.14E-90 T 13-10-2018 MADE_1019215 3a11660bf3e2bdd54333b3c07b98b2ad 451 Gene3D G3DSA:2.40.160.60 26 451 1.1E-122 T 13-10-2018 MADE_1019215 3a11660bf3e2bdd54333b3c07b98b2ad 451 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 17 451 3.7E-110 T 13-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) MADE_1016805 5840e2c2a862c92b21173ca0f82a78dc 256 Pfam PF13391 HNH endonuclease 159 211 6.8E-9 T 13-10-2018 IPR003615 HNH nuclease MADE_1008265 a0f87077493d93e319948efe3a4e2b89 381 Gene3D G3DSA:3.40.50.2000 190 362 4.1E-36 T 13-10-2018 MADE_1008265 a0f87077493d93e319948efe3a4e2b89 381 Gene3D G3DSA:3.40.50.2000 23 372 4.1E-36 T 13-10-2018 MADE_1008265 a0f87077493d93e319948efe3a4e2b89 381 Pfam PF00534 Glycosyl transferases group 1 201 357 5.7E-27 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1008265 a0f87077493d93e319948efe3a4e2b89 381 SUPERFAMILY SSF53756 8 379 1.03E-49 T 13-10-2018 MADE_1014385 5adb0fcdc75327df764b13877132d254 273 Pfam PF04383 KilA-N domain 20 140 8.1E-25 T 13-10-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MADE_1014385 5adb0fcdc75327df764b13877132d254 273 SMART SM01252 11 140 6.2E-51 T 13-10-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding MADE_1020385 d751d4eb6603d05b7055668342eba466 96 SUPERFAMILY SSF47413 16 66 1.35E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1020385 d751d4eb6603d05b7055668342eba466 96 Gene3D G3DSA:1.10.260.40 7 76 1.1E-6 T 13-10-2018 MADE_1020385 d751d4eb6603d05b7055668342eba466 96 Pfam PF13560 Helix-turn-helix domain 16 81 9.4E-8 T 13-10-2018 MADE_1000850 38f2a9af49246478e085b5ec91d1ec3a 342 Pfam PF07751 Abi-like protein 34 257 7.6E-51 T 13-10-2018 IPR011664 Abortive infection system protein AbiD/AbiF-like MADE_1000850 38f2a9af49246478e085b5ec91d1ec3a 342 PIRSF PIRSF034934 144 340 4.2E-31 T 13-10-2018 IPR017034 Abortive infection system protein AbiD/AbiF MADE_1000850 38f2a9af49246478e085b5ec91d1ec3a 342 PIRSF PIRSF034934 2 163 2.3E-26 T 13-10-2018 IPR017034 Abortive infection system protein AbiD/AbiF MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 TIGRFAM TIGR00835 agcS: amino acid carrier protein 21 546 9.2E-178 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 PRINTS PR00175 Sodium/alanine symporter signature 93 115 1.0E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 PRINTS PR00175 Sodium/alanine symporter signature 184 202 1.0E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 PRINTS PR00175 Sodium/alanine symporter signature 456 478 1.0E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 PRINTS PR00175 Sodium/alanine symporter signature 212 231 1.0E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 PRINTS PR00175 Sodium/alanine symporter signature 307 325 1.0E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 PRINTS PR00175 Sodium/alanine symporter signature 515 535 1.0E-51 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 93 108 - T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_1011630 43ed2ed2271470556154c76cf70b968e 552 Pfam PF01235 Sodium:alanine symporter family 56 552 1.1E-140 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 MADE_000001023105 184893b479398d0efa8b721faaa7734d 207 Pfam PF00924 Mechanosensitive ion channel 61 170 4.0E-9 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_000001023105 184893b479398d0efa8b721faaa7734d 207 SUPERFAMILY SSF50182 105 170 1.47E-7 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1006115 ed5b4c546f35ce488d9b64458ecdfc6f 88 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 8 86 3.6E-13 T 13-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 MADE_1006115 ed5b4c546f35ce488d9b64458ecdfc6f 88 Hamap MF_00404 Probable oxaloacetate decarboxylase gamma chain [oadG]. 1 88 25.641 T 13-10-2018 IPR023424 Oxaloacetate decarboxylase gamma chain, probable GO:0008948 KEGG: 00620+4.1.1.3 MADE_1006115 ed5b4c546f35ce488d9b64458ecdfc6f 88 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 12 83 2.1E-15 T 13-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 MADE_1003640 36f907b699a23e2d16d4dc32058acc9a 409 SUPERFAMILY SSF51556 30 406 4.65E-86 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1003640 36f907b699a23e2d16d4dc32058acc9a 409 Gene3D G3DSA:3.20.20.140 28 409 5.9E-130 T 13-10-2018 MADE_1003640 36f907b699a23e2d16d4dc32058acc9a 409 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 33 400 2.4E-94 T 13-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 MADE_1016960 536039c17b05469ee92d03d262a9e346 476 SUPERFAMILY SSF50182 193 260 3.92E-11 T 13-10-2018 IPR010920 LSM domain superfamily MADE_1016960 536039c17b05469ee92d03d262a9e346 476 Pfam PF00924 Mechanosensitive ion channel 156 405 5.2E-42 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 MADE_1019355 d946c148c33d31a5cd6436a91f5ccfdf 398 Pfam PF13372 Alginate export 43 175 2.8E-8 T 13-10-2018 IPR025388 Alginate export domain MADE_1019355 d946c148c33d31a5cd6436a91f5ccfdf 398 SUPERFAMILY SSF56935 44 390 1.83E-6 T 13-10-2018 MADE_1008180 9ed2d3d61cd4cdbba70cd78dfecf361e 286 Pfam PF00535 Glycosyl transferase family 2 4 115 3.8E-25 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1008180 9ed2d3d61cd4cdbba70cd78dfecf361e 286 SUPERFAMILY SSF53448 3 202 7.69E-43 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008180 9ed2d3d61cd4cdbba70cd78dfecf361e 286 Gene3D G3DSA:3.90.550.10 2 253 1.1E-45 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008995 34e055ea3ed65ab42008c5bcd5c66843 187 Gene3D G3DSA:3.40.30.10 1 186 2.4E-61 T 13-10-2018 MADE_1008995 34e055ea3ed65ab42008c5bcd5c66843 187 SUPERFAMILY SSF52833 1 186 1.99E-55 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1008995 34e055ea3ed65ab42008c5bcd5c66843 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 9.3E-103 T 13-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 MADE_1008995 34e055ea3ed65ab42008c5bcd5c66843 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 181 8.2E-6 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1008995 34e055ea3ed65ab42008c5bcd5c66843 187 PIRSF PIRSF000239 1 187 2.9E-52 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1008995 34e055ea3ed65ab42008c5bcd5c66843 187 Pfam PF00578 AhpC/TSA family 9 133 1.2E-34 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 MADE_1006160 027c37bf7c4ed3fb3d88e8d27df7ea39 227 Pfam PF04012 PspA/IM30 family 2 215 4.4E-45 T 13-10-2018 IPR007157 PspA/IM30 MADE_1006160 027c37bf7c4ed3fb3d88e8d27df7ea39 227 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 217 7.9E-94 T 13-10-2018 IPR014319 Phage shock protein, PspA MADE_000001021305 8853e5583ce5165df4e62a0fa2fb0846 165 Pfam PF01863 Protein of unknown function DUF45 93 151 2.1E-10 T 13-10-2018 IPR002725 Protein of unknown function DUF45 MADE_000001021305 8853e5583ce5165df4e62a0fa2fb0846 165 Gene3D G3DSA:3.30.2010.10 79 156 3.7E-7 T 13-10-2018 MADE_1013605 8e410951831300088e8f36f86e89d103 100 SUPERFAMILY SSF54637 2 90 1.94E-6 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1015405 d3e8a4309ebdf8e1367612c079ddcaad 170 Pfam PF04239 Protein of unknown function (DUF421) 97 160 1.2E-12 T 13-10-2018 IPR007353 Protein of unknown function DUF421 MADE_1015405 d3e8a4309ebdf8e1367612c079ddcaad 170 Gene3D G3DSA:3.30.240.20 88 160 1.9E-18 T 13-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 PRINTS PR00143 Citrate synthase signature 124 137 1.1E-36 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 PRINTS PR00143 Citrate synthase signature 249 269 1.1E-36 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 PRINTS PR00143 Citrate synthase signature 174 189 1.1E-36 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 PRINTS PR00143 Citrate synthase signature 306 322 1.1E-36 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 PRINTS PR00143 Citrate synthase signature 326 340 1.1E-36 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 PRINTS PR00143 Citrate synthase signature 196 224 1.1E-36 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 PIRSF PIRSF001369 1 373 3.8E-116 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 9 373 4.1E-157 T 13-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 Pfam PF00285 Citrate synthase, C-terminal domain 9 355 7.1E-116 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 Gene3D G3DSA:1.10.230.10 222 320 2.3E-121 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 Gene3D G3DSA:1.10.580.10 30 353 2.3E-121 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 MADE_1015705 3ce4dda1f3ac91ac49265761a51d9d4d 373 SUPERFAMILY SSF48256 9 365 2.36E-126 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 MADE_1000645 e9c8f330f033f7598a421c6589ec5adc 373 Pfam PF12698 ABC-2 family transporter protein 24 362 1.6E-30 T 13-10-2018 MADE_1015870 49619270f0533cb7a9f1a8b9f5c88490 373 Gene3D G3DSA:3.20.20.70 1 372 4.1E-130 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1015870 49619270f0533cb7a9f1a8b9f5c88490 373 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 336 1.1E-82 T 13-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 MADE_1015870 49619270f0533cb7a9f1a8b9f5c88490 373 SUPERFAMILY SSF51395 2 363 1.83E-116 T 13-10-2018 MADE_1009175 edd15cbf92a3a6b97ba1d23e613a3f56 115 Gene3D G3DSA:3.10.20.280 1 90 4.9E-33 T 13-10-2018 IPR037021 RnfH superfamily MADE_1009175 edd15cbf92a3a6b97ba1d23e613a3f56 115 Pfam PF03658 RnfH family Ubiquitin 6 88 2.9E-34 T 13-10-2018 IPR005346 RnfH protein MADE_1009175 edd15cbf92a3a6b97ba1d23e613a3f56 115 Hamap MF_00460 Protein RnfH [rnfH]. 6 96 25.351 T 13-10-2018 IPR005346 RnfH protein MADE_1009175 edd15cbf92a3a6b97ba1d23e613a3f56 115 SUPERFAMILY SSF54285 5 80 1.37E-25 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp MADE_1012380 4ab8fdbe9fa293af7f0815f9c725a13a 421 Gene3D G3DSA:3.50.50.60 1 281 1.1E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1012380 4ab8fdbe9fa293af7f0815f9c725a13a 421 Pfam PF01593 Flavin containing amine oxidoreductase 12 269 1.7E-18 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 MADE_1012380 4ab8fdbe9fa293af7f0815f9c725a13a 421 SUPERFAMILY SSF51905 4 415 3.63E-48 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1005635 d2382357c9bd2aaf4d41a52b73117456 990 Pfam PF13700 Domain of unknown function (DUF4158) 5 168 3.1E-29 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 MADE_1005635 d2382357c9bd2aaf4d41a52b73117456 990 Pfam PF01526 Tn3 transposase DDE domain 586 972 1.6E-150 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 MADE_1000580 6ed0b35e07311d0801d078b375f7e177 319 Pfam PF13182 Protein of unknown function (DUF4007) 5 315 1.0E-68 T 13-10-2018 IPR025248 Domain of unknown function DUF4007 MADE_1007030 dd55824a61c843cdfaaf9b09a72cc1c8 123 Gene3D G3DSA:3.40.50.2300 2 119 1.5E-17 T 13-10-2018 MADE_1007030 dd55824a61c843cdfaaf9b09a72cc1c8 123 SUPERFAMILY SSF52172 3 121 1.25E-17 T 13-10-2018 IPR011006 CheY-like superfamily MADE_1007030 dd55824a61c843cdfaaf9b09a72cc1c8 123 SMART SM00448 4 115 6.0E-5 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_1007030 dd55824a61c843cdfaaf9b09a72cc1c8 123 Pfam PF00072 Response regulator receiver domain 7 114 2.7E-9 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 MADE_000001022990 21aa86b9851283b39cd2e05c18c8163e 392 Gene3D G3DSA:3.40.50.720 1 392 9.5E-173 T 13-10-2018 MADE_000001022990 21aa86b9851283b39cd2e05c18c8163e 392 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 392 53.796 T 13-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_000001022990 21aa86b9851283b39cd2e05c18c8163e 392 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 80 7.0E-38 T 13-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_000001022990 21aa86b9851283b39cd2e05c18c8163e 392 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 317 2.9E-111 T 13-10-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_000001022990 21aa86b9851283b39cd2e05c18c8163e 392 Pfam PF07055 Enoyl reductase FAD binding domain 323 386 3.8E-25 T 13-10-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 MADE_1010080 56ea8df9494e18cb30a592e096706ba4 468 Pfam PF10544 T5orf172 domain 335 424 1.4E-12 T 13-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding MADE_1010080 56ea8df9494e18cb30a592e096706ba4 468 SMART SM00974 345 428 3.9E-31 T 13-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding MADE_1010080 56ea8df9494e18cb30a592e096706ba4 468 Pfam PF13250 Domain of unknown function (DUF4041) 179 234 3.2E-22 T 13-10-2018 IPR025280 Domain of unknown function DUF4041 MADE_1015880 6bffde4300876375b174fb1af11e2f2f 605 Gene3D G3DSA:3.90.1150.10 418 556 8.1E-18 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1015880 6bffde4300876375b174fb1af11e2f2f 605 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 144 552 6.8E-61 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 MADE_1015880 6bffde4300876375b174fb1af11e2f2f 605 Gene3D G3DSA:3.40.640.10 138 417 1.6E-48 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1015880 6bffde4300876375b174fb1af11e2f2f 605 SUPERFAMILY SSF53383 150 554 2.56E-52 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1007415 6d0afa897dd4e53c352291a0f0e9913d 205 Pfam PF10671 Toxin co-regulated pilus biosynthesis protein Q 115 190 1.8E-15 T 13-10-2018 IPR018927 Toxin co-regulated pilus biosynthesis protein Q, C-terminal MADE_1019940 46d16adad0a4ba5d2814c4f756393681 167 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 9 114 4.5E-15 T 13-10-2018 IPR012659 Conserved hypothetical protein CHP02444 MADE_1019940 46d16adad0a4ba5d2814c4f756393681 167 Pfam PF09523 Protein of unknown function (DUF2390) 11 112 1.6E-20 T 13-10-2018 IPR012659 Conserved hypothetical protein CHP02444 MADE_1003935 be96b541ae390a1f07c22118406fd422 334 Pfam PF01048 Phosphorylase superfamily 38 325 1.1E-44 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 MADE_1003935 be96b541ae390a1f07c22118406fd422 334 SUPERFAMILY SSF53167 39 309 1.48E-38 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 MADE_1008165 9fc022294d5c0ba40dd1baaf22b9c7e3 379 Pfam PF13439 Glycosyltransferase Family 4 126 179 5.1E-9 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 MADE_1008165 9fc022294d5c0ba40dd1baaf22b9c7e3 379 Gene3D G3DSA:3.40.50.2000 176 361 4.9E-48 T 13-10-2018 MADE_1008165 9fc022294d5c0ba40dd1baaf22b9c7e3 379 Gene3D G3DSA:3.40.50.2000 34 369 4.9E-48 T 13-10-2018 MADE_1008165 9fc022294d5c0ba40dd1baaf22b9c7e3 379 SUPERFAMILY SSF53756 10 378 3.14E-54 T 13-10-2018 MADE_1008165 9fc022294d5c0ba40dd1baaf22b9c7e3 379 Pfam PF00534 Glycosyl transferases group 1 195 345 2.6E-28 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 MADE_1012600 8738862f49c5186633eb117f7dfd5b00 184 Pfam PF07963 Prokaryotic N-terminal methylation motif 21 41 1.8E-4 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012600 8738862f49c5186633eb117f7dfd5b00 184 Gene3D G3DSA:3.30.700.10 22 177 1.0E-9 T 13-10-2018 MADE_1012600 8738862f49c5186633eb117f7dfd5b00 184 SUPERFAMILY SSF54523 22 153 1.18E-13 T 13-10-2018 MADE_1012600 8738862f49c5186633eb117f7dfd5b00 184 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 42 1.8E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1013405 c3119ceddd90fd75c46462b01227ece4 264 Pfam PF09955 Predicted integral membrane protein (DUF2189) 78 191 1.5E-24 T 13-10-2018 IPR018692 Predicted integral membrane protein DUF2189 MADE_1001235 a2480340261f17ecd6957564829b44cd 300 Gene3D G3DSA:3.40.50.300 28 186 5.8E-14 T 13-10-2018 MADE_1001235 a2480340261f17ecd6957564829b44cd 300 Pfam PF13401 AAA domain 42 169 4.3E-25 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1001235 a2480340261f17ecd6957564829b44cd 300 SUPERFAMILY SSF52540 6 252 3.93E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1012605 ff8e34fbb7a9f3d35150cc9ad59c707e 209 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 33 9.8E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1012605 ff8e34fbb7a9f3d35150cc9ad59c707e 209 PIRSF PIRSF004525 1 209 2.2E-29 T 13-10-2018 IPR016419 Prepilin peptidase-dependent protein B, predicted MADE_1016125 3feb9f60c4f9136b7486f4458c84a46e 118 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 11 106 2.4E-5 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_1016125 3feb9f60c4f9136b7486f4458c84a46e 118 Gene3D G3DSA:3.30.2310.20 2 111 3.2E-8 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_000001021450 fa5c5f63e6ba1f82184965c4a7cf6167 312 SUPERFAMILY SSF51395 1 308 1.19E-68 T 13-10-2018 MADE_000001021450 fa5c5f63e6ba1f82184965c4a7cf6167 312 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 309 54.235 T 13-10-2018 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 MADE_000001021450 fa5c5f63e6ba1f82184965c4a7cf6167 312 Gene3D G3DSA:3.20.20.70 1 241 4.4E-79 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_000001021450 fa5c5f63e6ba1f82184965c4a7cf6167 312 PIRSF PIRSF006621 1 312 2.0E-78 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_000001021450 fa5c5f63e6ba1f82184965c4a7cf6167 312 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_000001021450 fa5c5f63e6ba1f82184965c4a7cf6167 312 Pfam PF01207 Dihydrouridine synthase (Dus) 4 281 8.5E-74 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 MADE_000001021450 fa5c5f63e6ba1f82184965c4a7cf6167 312 Gene3D G3DSA:1.20.225.30 242 310 3.4E-22 T 13-10-2018 MADE_1016760 ba7874110ea60ab60a1128b1933821a8 66 Pfam PF04024 PspC domain 7 64 1.3E-16 T 13-10-2018 IPR007168 Phage shock protein, PspC, N-terminal MADE_1019420 8a9b9185abf8876b812bb0a4f70b29b8 402 Gene3D G3DSA:1.20.1250.20 7 196 2.0E-42 T 13-10-2018 MADE_1019420 8a9b9185abf8876b812bb0a4f70b29b8 402 Pfam PF07690 Major Facilitator Superfamily 22 360 9.2E-32 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1019420 8a9b9185abf8876b812bb0a4f70b29b8 402 SUPERFAMILY SSF103473 13 360 1.27E-46 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1019420 8a9b9185abf8876b812bb0a4f70b29b8 402 Gene3D G3DSA:1.20.1250.20 287 364 1.1E-16 T 13-10-2018 MADE_1016930 e9b8254ab04b1721d0eaf8132d74e70b 587 Pfam PF00691 OmpA family 480 565 7.9E-12 T 13-10-2018 IPR006665 OmpA-like domain MADE_1016930 e9b8254ab04b1721d0eaf8132d74e70b 587 Gene3D G3DSA:3.30.1330.60 457 581 1.6E-14 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1016930 e9b8254ab04b1721d0eaf8132d74e70b 587 SUPERFAMILY SSF103088 469 566 2.75E-15 T 13-10-2018 IPR036737 OmpA-like domain superfamily MADE_1001305 d666e962b4e520aa612da06ec39208ed 158 PIRSF PIRSF018472 1 158 2.5E-55 T 13-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type MADE_1001305 d666e962b4e520aa612da06ec39208ed 158 Pfam PF04093 rod shape-determining protein MreD 5 150 3.0E-31 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MADE_1001305 d666e962b4e520aa612da06ec39208ed 158 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 5 150 6.7E-44 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 MADE_1009605 04a56ea8fd7b733d326e483dcca3ac1a 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 8.4E-14 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1009605 04a56ea8fd7b733d326e483dcca3ac1a 207 Gene3D G3DSA:1.10.357.10 2 207 1.7E-60 T 13-10-2018 MADE_1009605 04a56ea8fd7b733d326e483dcca3ac1a 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 13-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site MADE_1009605 04a56ea8fd7b733d326e483dcca3ac1a 207 SUPERFAMILY SSF48498 81 205 3.16E-40 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily MADE_1009605 04a56ea8fd7b733d326e483dcca3ac1a 207 SUPERFAMILY SSF46689 3 75 4.72E-19 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 MADE_1009605 04a56ea8fd7b733d326e483dcca3ac1a 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.4E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1009605 04a56ea8fd7b733d326e483dcca3ac1a 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.4E-8 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 MADE_1008185 3ae2112c1b06bea742b0009e163e7876 309 Pfam PF00535 Glycosyl transferase family 2 15 165 1.5E-29 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1008185 3ae2112c1b06bea742b0009e163e7876 309 SUPERFAMILY SSF53448 10 265 1.58E-51 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1008185 3ae2112c1b06bea742b0009e163e7876 309 Gene3D G3DSA:3.90.550.10 2 228 3.8E-52 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1007080 482feed037b05c773650efd38017163e 231 SUPERFAMILY SSF81342 6 201 1.83E-37 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MADE_1007080 482feed037b05c773650efd38017163e 231 Gene3D G3DSA:1.20.950.20 1 174 1.2E-17 T 13-10-2018 MADE_1007080 482feed037b05c773650efd38017163e 231 Pfam PF01292 Prokaryotic cytochrome b561 11 185 9.1E-28 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MADE_1008245 629bbc2b3bdca0a8f4ba4115974f8640 639 Pfam PF01757 Acyltransferase family 29 347 2.3E-26 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MADE_1008245 629bbc2b3bdca0a8f4ba4115974f8640 639 SUPERFAMILY SSF52266 431 631 4.58E-5 T 13-10-2018 MADE_1013665 7843c137372c605b8ed5ba48f64510d8 77 Pfam PF10982 Protein of unknown function (DUF2789) 1 75 5.4E-30 T 13-10-2018 IPR021250 Protein of unknown function DUF2789 MADE_1013665 7843c137372c605b8ed5ba48f64510d8 77 Gene3D G3DSA:1.10.10.1130 1 77 1.7E-28 T 13-10-2018 MADE_1009245 54a7e9b7b067fd282d2b8e6c73661542 201 TIGRFAM TIGR04498 AbiV_defense: abortive infection protein, AbiV family 1 141 6.1E-42 T 13-10-2018 IPR030987 Abortive infection protein, AbiV family MADE_1001880 b20be53a2e7c44132b15268f66f5df05 163 Pfam PF04214 Protein of unknown function, DUF 62 129 3.3E-26 T 13-10-2018 IPR007332 Protein of unknown function DUF411 MADE_1001880 b20be53a2e7c44132b15268f66f5df05 163 SUPERFAMILY SSF52833 29 108 3.76E-5 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1011955 72ab4390abf1c3733c3661a9e20dbd33 521 SUPERFAMILY SSF56801 13 520 3.27E-106 T 13-10-2018 MADE_1011955 72ab4390abf1c3733c3661a9e20dbd33 521 Gene3D G3DSA:3.40.50.12780 2 417 9.0E-75 T 13-10-2018 MADE_1011955 72ab4390abf1c3733c3661a9e20dbd33 521 Gene3D G3DSA:3.30.300.310 421 521 7.4E-26 T 13-10-2018 MADE_1011955 72ab4390abf1c3733c3661a9e20dbd33 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 509 4.8E-13 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain MADE_1011955 72ab4390abf1c3733c3661a9e20dbd33 521 Pfam PF00501 AMP-binding enzyme 15 425 9.4E-63 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 MADE_1004760 1f3e4a53bdea42897a9f2ea972ca3ab6 236 Pfam PF00005 ABC transporter 47 187 4.4E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004760 1f3e4a53bdea42897a9f2ea972ca3ab6 236 SUPERFAMILY SSF52540 26 219 7.86E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004760 1f3e4a53bdea42897a9f2ea972ca3ab6 236 SMART SM00382 55 236 1.8E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004760 1f3e4a53bdea42897a9f2ea972ca3ab6 236 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1004760 1f3e4a53bdea42897a9f2ea972ca3ab6 236 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 31 223 5.7E-69 T 13-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 MADE_1004760 1f3e4a53bdea42897a9f2ea972ca3ab6 236 Gene3D G3DSA:3.40.50.300 23 233 3.9E-43 T 13-10-2018 MADE_1003955 6e1cef9e95a7b7d0e8dc8aab97384c38 149 Pfam PF02643 Uncharacterized ACR, COG1430 46 148 4.3E-32 T 13-10-2018 IPR003795 Protein of unknown function DUF192 MADE_1003955 6e1cef9e95a7b7d0e8dc8aab97384c38 149 Gene3D G3DSA:2.60.120.1140 27 149 2.1E-39 T 13-10-2018 IPR038695 Saro_0823-like superfamily MADE_1015900 bee333da4535ac25dd9183b6abf3a557 259 SUPERFAMILY SSF111364 43 259 1.57E-33 T 13-10-2018 IPR036777 Nucleoside-specific channel-forming protein, Tsx-like superfamily GO:0009279 MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 SMART SM00422 1 69 5.9E-20 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 SUPERFAMILY SSF46955 1 120 2.78E-26 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 Pfam PF13411 MerR HTH family regulatory protein 1 66 1.7E-15 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.8E-8 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.8E-8 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.8E-8 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 MADE_1012005 e4a44928b757296b37dee107729e7ba2 137 Gene3D G3DSA:1.10.1660.10 1 117 3.2E-28 T 13-10-2018 MADE_1010840 564b1d71ddec29e81d0c7fb249e2716e 357 Pfam PF01594 AI-2E family transporter 20 345 1.9E-66 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like MADE_1007560 a1f34bd8720b3a9a4f64c736d102f28c 193 Gene3D G3DSA:3.40.50.1470 1 193 1.5E-68 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MADE_1007560 a1f34bd8720b3a9a4f64c736d102f28c 193 Pfam PF01195 Peptidyl-tRNA hydrolase 6 188 1.8E-50 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MADE_1007560 a1f34bd8720b3a9a4f64c736d102f28c 193 SUPERFAMILY SSF53178 4 190 2.88E-64 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 MADE_1007560 a1f34bd8720b3a9a4f64c736d102f28c 193 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 182 32.496 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MADE_1007560 a1f34bd8720b3a9a4f64c736d102f28c 193 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 MADE_1007560 a1f34bd8720b3a9a4f64c736d102f28c 193 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 190 1.1E-63 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 MADE_1016065 0137bed3e34dcfb890ff6387c04204ae 366 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 350 4.9E-77 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 MADE_1016065 0137bed3e34dcfb890ff6387c04204ae 366 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 349 7.3E-122 T 13-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 MADE_1007900 08e1bc07726fcebe849790f41a193775 119 Gene3D G3DSA:1.10.10.10 3 119 2.0E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1007900 08e1bc07726fcebe849790f41a193775 119 Pfam PF01638 HxlR-like helix-turn-helix 31 117 3.8E-23 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type MADE_1007900 08e1bc07726fcebe849790f41a193775 119 SUPERFAMILY SSF46785 17 116 3.39E-29 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1010140 811f078849064b8825ac64fc5d6b7765 444 Pfam PF00209 Sodium:neurotransmitter symporter family 4 118 1.4E-21 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1010140 811f078849064b8825ac64fc5d6b7765 444 Pfam PF00209 Sodium:neurotransmitter symporter family 137 443 3.8E-23 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1010140 811f078849064b8825ac64fc5d6b7765 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 2.7E-10 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1010140 811f078849064b8825ac64fc5d6b7765 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 2.7E-10 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1010140 811f078849064b8825ac64fc5d6b7765 444 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 2.7E-10 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 MADE_1010140 811f078849064b8825ac64fc5d6b7765 444 SUPERFAMILY SSF161070 4 443 7.45E-117 T 13-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 MADE_1019025 041be637ae92b8bc2ad74e52a8ef37bb 495 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 9 464 7.8E-125 T 13-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 MADE_1019025 041be637ae92b8bc2ad74e52a8ef37bb 495 Pfam PF03553 Na+/H+ antiporter family 162 463 6.0E-49 T 13-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MADE_1006010 91c90d077d6b8ebe975630a723ac9e84 254 Pfam PF13614 AAA domain 1 181 1.6E-49 T 13-10-2018 IPR025669 AAA domain MADE_1006010 91c90d077d6b8ebe975630a723ac9e84 254 Gene3D G3DSA:3.40.50.300 1 254 2.6E-67 T 13-10-2018 MADE_1006010 91c90d077d6b8ebe975630a723ac9e84 254 SUPERFAMILY SSF52540 1 253 1.44E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1018295 9beec3121ade4d303e2434185d2c03e8 192 SUPERFAMILY SSF110997 112 191 2.35E-21 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MADE_1018295 9beec3121ade4d303e2434185d2c03e8 192 Pfam PF05036 Sporulation related domain 114 179 1.5E-16 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 MADE_1018295 9beec3121ade4d303e2434185d2c03e8 192 Gene3D G3DSA:3.30.70.1070 109 189 7.8E-29 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 MADE_000001021155 6f7845ab718b4475662c2bc854709d23 277 SUPERFAMILY SSF117396 1 253 1.57E-65 T 13-10-2018 IPR036520 UPF0759 superfamily MADE_000001021155 6f7845ab718b4475662c2bc854709d23 277 Pfam PF01904 Protein of unknown function DUF72 17 251 6.8E-58 T 13-10-2018 IPR002763 Protein of unknown function DUF72 MADE_000001021155 6f7845ab718b4475662c2bc854709d23 277 Gene3D G3DSA:3.20.20.410 1 267 7.3E-42 T 13-10-2018 IPR036520 UPF0759 superfamily MADE_1000930 b6223417978a1b79ce47ebd9178025ce 493 SMART SM00283 231 492 1.9E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1000930 b6223417978a1b79ce47ebd9178025ce 493 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 276 458 2.9E-36 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1000930 b6223417978a1b79ce47ebd9178025ce 493 Gene3D G3DSA:1.10.287.950 172 493 4.2E-52 T 13-10-2018 MADE_1000930 b6223417978a1b79ce47ebd9178025ce 493 SUPERFAMILY SSF58104 237 493 5.49E-54 T 13-10-2018 MADE_1019995 103345468d84a0f02ce7733b3428ff22 592 Pfam PF00112 Papain family cysteine protease 43 220 7.2E-5 T 13-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 MADE_1019995 103345468d84a0f02ce7733b3428ff22 592 SUPERFAMILY SSF54001 43 240 2.39E-24 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily MADE_1019995 103345468d84a0f02ce7733b3428ff22 592 SUPERFAMILY SSF53474 412 523 2.29E-5 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1019995 103345468d84a0f02ce7733b3428ff22 592 Gene3D G3DSA:3.90.70.10 4 240 3.6E-51 T 13-10-2018 MADE_1002435 4d60723779816881ca993c21f431019e 308 SUPERFAMILY SSF54909 1 300 3.58E-87 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel MADE_1002435 4d60723779816881ca993c21f431019e 308 Pfam PF04261 Dyp-type peroxidase family 37 296 3.2E-51 T 13-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MADE_1002435 4d60723779816881ca993c21f431019e 308 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 7 297 2.6E-47 T 13-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 MADE_1018175 b56b3759c0647bbb9b41f0031774fe65 274 SUPERFAMILY SSF53850 23 239 9.75E-21 T 13-10-2018 MADE_1018175 b56b3759c0647bbb9b41f0031774fe65 274 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 28 258 1.2E-50 T 13-10-2018 MADE_1018175 b56b3759c0647bbb9b41f0031774fe65 274 Gene3D G3DSA:3.40.190.10 107 207 3.6E-35 T 13-10-2018 MADE_1018175 b56b3759c0647bbb9b41f0031774fe65 274 Gene3D G3DSA:3.40.190.10 28 236 3.6E-35 T 13-10-2018 MADE_1000080 fb22b5a5be71c770e2592547be6299d9 217 Gene3D G3DSA:3.40.50.880 1 217 2.8E-86 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1000080 fb22b5a5be71c770e2592547be6299d9 217 SUPERFAMILY SSF52317 1 216 8.79E-57 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1000080 fb22b5a5be71c770e2592547be6299d9 217 PIRSF PIRSF006320 1 217 1.7E-100 T 13-10-2018 IPR026041 Glyoxalase ElbB MADE_1004410 0fd69982ac8cda8d48dce2ee5a0492c9 423 Pfam PF01384 Phosphate transporter family 26 409 1.6E-110 T 13-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 MADE_1009865 0507fc615453abb45cf085c134d71269 190 ProSitePatterns PS01293 Nudix CoA signature. 47 67 - T 13-10-2018 IPR000059 NUDIX hydrolase, NudL, conserved site GO:0000287|GO:0009132|GO:0016818|GO:0030145 Reactome: R-HSA-390918|Reactome: R-HSA-9033241 MADE_1009865 0507fc615453abb45cf085c134d71269 190 SUPERFAMILY SSF55811 9 184 2.57E-36 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 MADE_1009865 0507fc615453abb45cf085c134d71269 190 Gene3D G3DSA:3.90.79.10 8 187 5.7E-51 T 13-10-2018 MADE_1009865 0507fc615453abb45cf085c134d71269 190 Pfam PF00293 NUDIX domain 29 143 1.3E-13 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 MADE_1009945 c564dcafcab2a95385a66418145fc3e4 201 Pfam PF04336 Acyl carrier protein phosphodiesterase 81 184 3.8E-28 T 13-10-2018 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 MADE_1005955 c291d35ba65d96b31903911aca8a6174 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 2.1E-27 T 13-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 MADE_1005955 c291d35ba65d96b31903911aca8a6174 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 5.5E-15 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MADE_1005955 c291d35ba65d96b31903911aca8a6174 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 5.5E-15 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MADE_1005955 c291d35ba65d96b31903911aca8a6174 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 5.5E-15 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MADE_1005955 c291d35ba65d96b31903911aca8a6174 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.3E-24 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MADE_1005955 c291d35ba65d96b31903911aca8a6174 89 PIRSF PIRSF004669 1 89 1.3E-26 T 13-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 MADE_1001405 d0e41f99818fb277308f9abbe758e107 113 Gene3D G3DSA:3.90.120.10 5 99 1.8E-15 T 13-10-2018 MADE_1001405 d0e41f99818fb277308f9abbe758e107 113 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 91 109 - T 13-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 MADE_1001405 d0e41f99818fb277308f9abbe758e107 113 SUPERFAMILY SSF53335 19 111 1.83E-14 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1001405 d0e41f99818fb277308f9abbe758e107 113 Pfam PF00145 C-5 cytosine-specific DNA methylase 27 106 1.7E-10 T 13-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 MADE_1011045 fe774805d29440d3e7e52334070f730e 73 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 4 64 3.5E-17 T 13-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system MADE_1011065 0742300ce7fa6a47d49de2a733f2158e 85 Gene3D G3DSA:3.40.1620.10 1 40 1.5E-5 T 13-10-2018 MADE_1011065 0742300ce7fa6a47d49de2a733f2158e 85 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 56 3.3E-11 T 13-10-2018 MADE_1011065 0742300ce7fa6a47d49de2a733f2158e 85 SUPERFAMILY SSF143120 1 74 1.24E-16 T 13-10-2018 IPR036165 YefM-like superfamily MADE_1011065 0742300ce7fa6a47d49de2a733f2158e 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 69 6.7E-15 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MADE_1016990 c973b62dde2bdf1d12ce481e9f8954d6 131 Pfam PF04134 Protein of unknown function, DUF393 3 110 6.8E-26 T 13-10-2018 IPR007263 Protein of unknown function DUF393 MADE_1001930 92b726a014ab5ffdc95a8c0b1a9e3959 112 Pfam PF11666 Protein of unknown function (DUF2933) 19 68 1.8E-20 T 13-10-2018 IPR021682 Protein of unknown function DUF2933 MADE_1011850 8fb8118d68004dcfa511f57eb6a36d29 78 SUPERFAMILY SSF53474 7 77 5.64E-13 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1011850 8fb8118d68004dcfa511f57eb6a36d29 78 Gene3D G3DSA:3.40.50.1820 1 78 3.9E-11 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1005540 1218ca782f7b4256169ec8e85c55364e 117 Pfam PF02411 MerT mercuric transport protein 3 114 1.3E-35 T 13-10-2018 IPR003457 Mercuric transport protein MerT GO:0015097|GO:0015694|GO:0016020 MADE_1009535 81d9ac5bf142efab1b91692e7718eae5 287 Pfam PF01734 Patatin-like phospholipase 5 72 1.0E-6 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MADE_1009535 81d9ac5bf142efab1b91692e7718eae5 287 Gene3D G3DSA:3.40.1090.10 87 229 3.8E-10 T 13-10-2018 MADE_1009535 81d9ac5bf142efab1b91692e7718eae5 287 Gene3D G3DSA:3.40.1090.10 1 77 4.2E-8 T 13-10-2018 MADE_1009535 81d9ac5bf142efab1b91692e7718eae5 287 SUPERFAMILY SSF52151 2 270 2.62E-34 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MADE_1005785 c9ab98fbc41ffcb70709b21e50d8f59c 142 Pfam PF02561 Flagellar protein FliS 7 122 3.7E-32 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 MADE_1005785 c9ab98fbc41ffcb70709b21e50d8f59c 142 TIGRFAM TIGR00208 fliS: flagellar protein FliS 8 122 6.3E-27 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 MADE_1005785 c9ab98fbc41ffcb70709b21e50d8f59c 142 Gene3D G3DSA:1.20.120.340 2 127 4.2E-36 T 13-10-2018 MADE_1005785 c9ab98fbc41ffcb70709b21e50d8f59c 142 SUPERFAMILY SSF101116 7 127 1.7E-35 T 13-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 MADE_1005785 c9ab98fbc41ffcb70709b21e50d8f59c 142 PIRSF PIRSF039090 1 133 5.4E-41 T 13-10-2018 IPR003713 Flagellar protein FliS GO:0044780 MADE_000001022950 ae0b40d4eabd507010ac5dca218589ba 77 Pfam PF04400 (Na+)-NQR maturation NqrM 22 63 3.7E-21 T 13-10-2018 IPR007495 (Na+)-NQR maturation factor NqrM MADE_1003770 c123e7dd17dfe9c9aa4de22d3084421c 148 Gene3D G3DSA:1.10.10.410 91 147 2.1E-19 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal MADE_1003770 c123e7dd17dfe9c9aa4de22d3084421c 148 SUPERFAMILY SSF89095 1 147 2.98E-41 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 MADE_1003770 c123e7dd17dfe9c9aa4de22d3084421c 148 Pfam PF09424 Yqey-like protein 5 146 5.9E-52 T 13-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 MADE_1003770 c123e7dd17dfe9c9aa4de22d3084421c 148 Gene3D G3DSA:1.10.1510.10 1 90 3.4E-25 T 13-10-2018 MADE_000001021020 2b5f23cc611652549f889eb51d739825 411 Pfam PF12146 Serine aminopeptidase, S33 89 290 2.5E-15 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 MADE_000001021020 2b5f23cc611652549f889eb51d739825 411 Gene3D G3DSA:3.40.50.1820 74 329 3.5E-30 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_000001021020 2b5f23cc611652549f889eb51d739825 411 SUPERFAMILY SSF53474 87 300 2.26E-23 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1018450 5b050caba1512ca13782b6b6896531d5 544 Gene3D G3DSA:3.40.640.10 118 382 1.1E-95 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1018450 5b050caba1512ca13782b6b6896531d5 544 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 60 436 5.1E-46 T 13-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 MADE_1018450 5b050caba1512ca13782b6b6896531d5 544 TIGRFAM TIGR03799 NOD_PanD_pyr: putative pyridoxal-dependent aspartate 1-decarboxylase 4 521 1.2E-257 T 13-10-2018 IPR022517 Aspartate 1-decarboxylase, pyridoxal-dependent KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 MADE_1018450 5b050caba1512ca13782b6b6896531d5 544 SUPERFAMILY SSF53383 18 523 3.23E-100 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1018450 5b050caba1512ca13782b6b6896531d5 544 Gene3D G3DSA:3.90.1150.170 45 518 1.1E-95 T 13-10-2018 MADE_000001022080 852cd3c56c7da286cbb8797f542f77ed 221 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 214 4.5E-46 T 13-10-2018 IPR006214 Bax inhibitor 1-related MADE_1016095 06654c7cd4c9a1a5433ae2be753531c8 530 Pfam PF14224 Domain of unknown function (DUF4331) 27 525 1.8E-138 T 13-10-2018 IPR025566 Protein of unknown function DUF4331 MADE_1016550 331f44b0040ab29cfcdc5fa5fd5de301 156 Pfam PF09990 Predicted membrane protein (DUF2231) 47 147 5.3E-18 T 13-10-2018 IPR019251 Domain of unknown function DUF2231, transmembrane MADE_1008000 dabd12a12b4e4235eae92c5b95416da0 809 Gene3D G3DSA:2.170.130.10 44 170 3.4E-15 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily MADE_1008000 dabd12a12b4e4235eae92c5b95416da0 809 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 163 1.7E-10 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain MADE_1008000 dabd12a12b4e4235eae92c5b95416da0 809 SUPERFAMILY SSF56935 27 809 2.49E-75 T 13-10-2018 MADE_1008000 dabd12a12b4e4235eae92c5b95416da0 809 ProSitePatterns PS00018 EF-hand calcium-binding domain. 292 304 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site MADE_1003885 4dd23d3b6897120f431a2e7e0d302f5d 172 Pfam PF01618 MotA/TolQ/ExbB proton channel family 61 165 2.3E-21 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MADE_1001570 26730394381e2481590e1e1bc88c5996 130 Gene3D G3DSA:2.60.40.1220 19 117 5.6E-17 T 13-10-2018 MADE_1001570 26730394381e2481590e1e1bc88c5996 130 Pfam PF04234 CopC domain 19 111 7.1E-19 T 13-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 MADE_1001570 26730394381e2481590e1e1bc88c5996 130 SUPERFAMILY SSF81296 18 112 5.95E-21 T 13-10-2018 IPR014756 Immunoglobulin E-set MADE_1003505 4bfb9ce3e2050953416e3d9729b53c52 675 Pfam PF01547 Bacterial extracellular solute-binding protein 317 563 2.1E-28 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein MADE_1003505 4bfb9ce3e2050953416e3d9729b53c52 675 SUPERFAMILY SSF53850 27 253 6.34E-16 T 13-10-2018 MADE_1003505 4bfb9ce3e2050953416e3d9729b53c52 675 SUPERFAMILY SSF53850 292 643 9.15E-54 T 13-10-2018 MADE_1003505 4bfb9ce3e2050953416e3d9729b53c52 675 Gene3D G3DSA:3.40.190.10 376 657 1.8E-98 T 13-10-2018 MADE_1003505 4bfb9ce3e2050953416e3d9729b53c52 675 Gene3D G3DSA:3.40.190.10 35 245 8.4E-7 T 13-10-2018 MADE_1003505 4bfb9ce3e2050953416e3d9729b53c52 675 Gene3D G3DSA:3.40.190.10 108 210 8.4E-7 T 13-10-2018 MADE_1003505 4bfb9ce3e2050953416e3d9729b53c52 675 Gene3D G3DSA:3.40.190.10 292 628 1.8E-98 T 13-10-2018 MADE_1003260 a7ebcf9576b524c4490038c25981c613 112 SUPERFAMILY SSF54427 5 108 2.32E-12 T 13-10-2018 IPR032710 NTF2-like domain superfamily MADE_1003260 a7ebcf9576b524c4490038c25981c613 112 Gene3D G3DSA:3.10.450.50 2 112 1.3E-11 T 13-10-2018 MADE_1003260 a7ebcf9576b524c4490038c25981c613 112 Pfam PF12680 SnoaL-like domain 14 102 2.7E-6 T 13-10-2018 IPR037401 SnoaL-like domain MADE_1018335 c2539b3300b8324cc9e921974fe60a0e 212 Pfam PF11172 Protein of unknown function (DUF2959) 13 210 5.4E-90 T 13-10-2018 IPR021342 Protein of unknown function DUF2959 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 Gene3D G3DSA:3.40.50.1370 9 297 1.2E-97 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 141 1.2E-41 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 44 58 5.8E-21 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 117 131 5.8E-21 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 280 291 5.8E-21 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 77 90 5.8E-21 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 219 229 5.8E-21 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 301 4.8E-94 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 SUPERFAMILY SSF53671 2 302 1.83E-87 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 Gene3D G3DSA:3.40.50.1370 131 288 1.2E-97 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 298 2.6E-44 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 263 1.4E-18 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 128 139 1.4E-18 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 46 65 1.4E-18 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002655 4936f3d1d4952eb319dea640001cdb2d 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 289 1.4E-18 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 MADE_1002690 d1f8f7c159c0fbffd4ed1803b12e7e37 322 Gene3D G3DSA:3.40.50.1820 23 322 3.8E-53 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1002690 d1f8f7c159c0fbffd4ed1803b12e7e37 322 Pfam PF12146 Serine aminopeptidase, S33 49 305 1.3E-59 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 MADE_1002690 d1f8f7c159c0fbffd4ed1803b12e7e37 322 SUPERFAMILY SSF53474 23 321 9.7E-42 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1010725 49b5f7cf6e04f567151c37d4cf1da218 232 SUPERFAMILY SSF51366 2 229 1.86E-77 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 MADE_1010725 49b5f7cf6e04f567151c37d4cf1da218 232 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 226 6.6E-61 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1010725 49b5f7cf6e04f567151c37d4cf1da218 232 SMART SM00934 5 226 3.6E-97 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1010725 49b5f7cf6e04f567151c37d4cf1da218 232 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 57 70 - T 13-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1010725 49b5f7cf6e04f567151c37d4cf1da218 232 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 225 2.2E-55 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_1010725 49b5f7cf6e04f567151c37d4cf1da218 232 Gene3D G3DSA:3.20.20.70 1 230 1.7E-84 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1010725 49b5f7cf6e04f567151c37d4cf1da218 232 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 231 39.041 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 MADE_000001020975 c75e1a9713eb770f1b8b01ef9dc85a37 265 Pfam PF01578 Cytochrome C assembly protein 39 263 2.9E-32 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MADE_000001022905 99323a12e3388aef50695e2649b3c8ba 244 Gene3D G3DSA:3.40.50.850 26 243 3.1E-58 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MADE_000001022905 99323a12e3388aef50695e2649b3c8ba 244 TIGRFAM TIGR03614 RutB: pyrimidine utilization protein B 22 241 7.1E-124 T 13-10-2018 IPR019916 Isochorismatase, RutB GO:0016811 KEGG: 00240+3.5.1.110 MADE_000001022905 99323a12e3388aef50695e2649b3c8ba 244 Pfam PF00857 Isochorismatase family 37 235 1.1E-42 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 MADE_000001022905 99323a12e3388aef50695e2649b3c8ba 244 SUPERFAMILY SSF52499 23 240 6.54E-58 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 MADE_1001340 092a52e6d7adea051b86d6382fe6bfdd 443 Gene3D G3DSA:3.30.2290.10 2 229 7.7E-82 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal MADE_1001340 092a52e6d7adea051b86d6382fe6bfdd 443 SUPERFAMILY SSF111283 8 442 3.92E-121 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 MADE_1001340 092a52e6d7adea051b86d6382fe6bfdd 443 Pfam PF01523 Putative modulator of DNA gyrase 28 320 4.9E-54 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 MADE_1016455 4ff5f6659bebdeb6564f5fe177792a7f 376 Gene3D G3DSA:2.40.160.10 83 376 6.1E-9 T 13-10-2018 IPR023614 Porin domain superfamily MADE_1016455 4ff5f6659bebdeb6564f5fe177792a7f 376 SUPERFAMILY SSF56935 7 376 3.05E-21 T 13-10-2018 MADE_1007410 30962696502f1841775a359b77d1c15e 311 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 7 308 41.586 T 13-10-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 MADE_1007410 30962696502f1841775a359b77d1c15e 311 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 8 308 1.1E-98 T 13-10-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 MADE_1007410 30962696502f1841775a359b77d1c15e 311 PIRSF PIRSF026649 5 306 3.2E-75 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MADE_1007410 30962696502f1841775a359b77d1c15e 311 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 8 298 1.1E-64 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 MADE_1000510 a33a41ebf14f1f62dd9a8dc0094b3e13 105 Gene3D G3DSA:3.30.70.120 2 101 3.3E-34 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal MADE_1000510 a33a41ebf14f1f62dd9a8dc0094b3e13 105 SUPERFAMILY SSF54913 6 87 1.08E-9 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta MADE_1000510 a33a41ebf14f1f62dd9a8dc0094b3e13 105 Pfam PF11582 Protein of unknown function (DUF3240) 3 100 4.7E-24 T 13-10-2018 IPR021634 Protein of unknown function DUF3240 MADE_1020310 d0be8ae21979820e8c3b24c31f0ddf98 100 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 23 95 2.9E-30 T 13-10-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 MADE_1015800 d0f4171353a622ce6316215767c086cc 195 Pfam PF10881 Protein of unknown function (DUF2726) 35 159 6.3E-37 T 13-10-2018 IPR024402 Domain of unknown function DUF2726 MADE_1015800 d0f4171353a622ce6316215767c086cc 195 PIRSF PIRSF028063 1 163 3.4E-13 T 13-10-2018 IPR014538 Uncharacterised conserved protein, topoisomerase zinc finger MADE_1020040 004fa64969ef8d3425c39eabd17557cd 127 Gene3D G3DSA:3.10.180.10 1 125 7.0E-32 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1020040 004fa64969ef8d3425c39eabd17557cd 127 SUPERFAMILY SSF54593 2 123 2.11E-19 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1020040 004fa64969ef8d3425c39eabd17557cd 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 119 8.0E-6 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_1007910 23f07628670997b85bcb0720553d769f 426 Pfam PF06181 Urate oxidase N-terminal 4 296 4.2E-133 T 13-10-2018 IPR010389 Urate oxidase N-terminal MADE_1010530 0c2c93ae975d7759285c84f56aed7c63 979 Pfam PF06048 Domain of unknown function (DUF927) 368 645 5.9E-77 T 13-10-2018 IPR009270 Domain of unknown function DUF927 MADE_1010530 0c2c93ae975d7759285c84f56aed7c63 979 SUPERFAMILY SSF57783 16 99 1.28E-7 T 13-10-2018 MADE_1010530 0c2c93ae975d7759285c84f56aed7c63 979 Gene3D G3DSA:3.40.1360.10 201 344 1.5E-6 T 13-10-2018 MADE_000001022140 d6acbacce0d33bfe505eafdb105ed8a9 130 Pfam PF04221 RelB antitoxin 41 114 2.2E-4 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ MADE_1013355 7c38a52eb41e235f0d592f011b3d9bab 288 ProSitePatterns PS00770 Aminotransferases class-IV signature. 186 215 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 MADE_1013355 7c38a52eb41e235f0d592f011b3d9bab 288 Pfam PF01063 Amino-transferase class IV 30 259 1.4E-43 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 MADE_1013355 7c38a52eb41e235f0d592f011b3d9bab 288 SUPERFAMILY SSF56752 3 284 1.7E-67 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 MADE_1013355 7c38a52eb41e235f0d592f011b3d9bab 288 Gene3D G3DSA:3.30.470.10 1 121 2.3E-29 T 13-10-2018 MADE_1013355 7c38a52eb41e235f0d592f011b3d9bab 288 Gene3D G3DSA:3.20.10.10 127 287 2.2E-49 T 13-10-2018 MADE_1006545 9ded7d761b8ec83f405c7f712f9b019b 428 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 422 39.198 T 13-10-2018 IPR006698 Uncharacterised protein family UPF0229 MADE_1006545 9ded7d761b8ec83f405c7f712f9b019b 428 Pfam PF04285 Protein of unknown function (DUF444) 3 419 9.3E-181 T 13-10-2018 IPR006698 Uncharacterised protein family UPF0229 MADE_1012065 38ece3faa83bf12b8e92be0aecbc50ca 382 PIRSF PIRSF016907 10 382 5.2E-122 T 13-10-2018 IPR011386 Putative ATP-NAD kinase MADE_1012065 38ece3faa83bf12b8e92be0aecbc50ca 382 Pfam PF01513 ATP-NAD kinase 13 376 2.1E-41 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 MADE_1012065 38ece3faa83bf12b8e92be0aecbc50ca 382 SUPERFAMILY SSF111331 83 149 3.05E-6 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily MADE_1019515 12ca15efa044c251e78ff452d1d5c3c8 93 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 7 90 1.4E-32 T 13-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 MADE_1004325 74b7ab11b6d031cc84523617912fffbf 392 Gene3D G3DSA:3.40.50.2300 150 282 5.3E-62 T 13-10-2018 MADE_1004325 74b7ab11b6d031cc84523617912fffbf 392 SUPERFAMILY SSF53822 28 386 8.38E-61 T 13-10-2018 IPR028082 Periplasmic binding protein-like I MADE_1004325 74b7ab11b6d031cc84523617912fffbf 392 Gene3D G3DSA:3.40.50.2300 31 355 5.3E-62 T 13-10-2018 MADE_1004325 74b7ab11b6d031cc84523617912fffbf 392 Pfam PF13458 Periplasmic binding protein 31 381 1.1E-41 T 13-10-2018 IPR028081 Leucine-binding protein domain MADE_1012960 6d4629eebd093bce7feac7b9ce62accb 112 Pfam PF02699 Preprotein translocase subunit 24 101 8.6E-26 T 13-10-2018 IPR003849 Preprotein translocase YajC MADE_1012960 6d4629eebd093bce7feac7b9ce62accb 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 6.5E-16 T 13-10-2018 IPR003849 Preprotein translocase YajC MADE_1012960 6d4629eebd093bce7feac7b9ce62accb 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 6.5E-16 T 13-10-2018 IPR003849 Preprotein translocase YajC MADE_1012960 6d4629eebd093bce7feac7b9ce62accb 112 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 104 7.1E-30 T 13-10-2018 IPR003849 Preprotein translocase YajC MADE_1012960 6d4629eebd093bce7feac7b9ce62accb 112 SMART SM01323 20 104 3.4E-38 T 13-10-2018 IPR003849 Preprotein translocase YajC MADE_1003655 7e17de175c697ba74354715e04245bcb 213 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 25 206 3.8E-33 T 13-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like MADE_1003655 7e17de175c697ba74354715e04245bcb 213 SUPERFAMILY SSF51197 13 208 9.75E-64 T 13-10-2018 MADE_1003655 7e17de175c697ba74354715e04245bcb 213 Gene3D G3DSA:2.60.120.590 11 212 1.5E-65 T 13-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily MADE_1004220 9674b3d9f06c14143a2433f6f3c2ba92 266 Pfam PF00005 ABC transporter 21 169 2.3E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 MADE_1004220 9674b3d9f06c14143a2433f6f3c2ba92 266 Gene3D G3DSA:3.40.50.300 1 249 1.2E-63 T 13-10-2018 MADE_1004220 9674b3d9f06c14143a2433f6f3c2ba92 266 SMART SM00382 29 224 1.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain MADE_1004220 9674b3d9f06c14143a2433f6f3c2ba92 266 SUPERFAMILY SSF52540 4 235 1.08E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004220 9674b3d9f06c14143a2433f6f3c2ba92 266 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 MADE_1004745 80ba45e8d9d55eb0e87f6f239bae10a7 398 Pfam PF12698 ABC-2 family transporter protein 16 387 2.1E-28 T 13-10-2018 MADE_1000640 1be0181ef57c67805c36c34a08ca2d0e 283 Pfam PF12698 ABC-2 family transporter protein 1 275 6.0E-31 T 13-10-2018 MADE_1011620 b00f4d5990f2d539658305650c92b4ec 108 Pfam PF13248 zinc-ribbon domain 4 27 1.1E-6 T 13-10-2018 MADE_1011620 b00f4d5990f2d539658305650c92b4ec 108 ProDom PD057827 ZN-RIBBON HI1126 PM0127 TRANSMEMBRANE ORF196EGC129 MEMBRANE SO2423 GLL0157 1 62 1.0E-18 T 13-10-2018 MADE_1004635 0fa00f923814f2be71da6abf3f12ed95 163 Gene3D G3DSA:3.30.450.20 5 140 2.9E-32 T 13-10-2018 MADE_1004635 0fa00f923814f2be71da6abf3f12ed95 163 SMART SM00091 12 78 0.003 T 13-10-2018 IPR000014 PAS domain MADE_1004635 0fa00f923814f2be71da6abf3f12ed95 163 SUPERFAMILY SSF55785 16 124 1.69E-9 T 13-10-2018 IPR035965 PAS domain superfamily MADE_1004635 0fa00f923814f2be71da6abf3f12ed95 163 Pfam PF08448 PAS fold 21 138 9.8E-7 T 13-10-2018 IPR013656 PAS fold-4 MADE_1003565 c110fef08f8f0aa74215c83c173baf23 193 Pfam PF05728 Uncharacterised protein family (UPF0227) 4 191 4.6E-49 T 13-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA MADE_1003565 c110fef08f8f0aa74215c83c173baf23 193 Gene3D G3DSA:3.40.50.1820 1 193 2.1E-54 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1003565 c110fef08f8f0aa74215c83c173baf23 193 SUPERFAMILY SSF53474 4 192 3.24E-16 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1000485 1ad48ea8b719df0ce93b90b4cfb499da 277 Pfam PF08534 Redoxin 146 257 3.8E-13 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 MADE_1000485 1ad48ea8b719df0ce93b90b4cfb499da 277 ProSitePatterns PS00194 Thioredoxin family active site. 163 181 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 MADE_1000485 1ad48ea8b719df0ce93b90b4cfb499da 277 SUPERFAMILY SSF52833 143 271 2.9E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1000485 1ad48ea8b719df0ce93b90b4cfb499da 277 Gene3D G3DSA:3.40.30.10 134 273 1.1E-30 T 13-10-2018 MADE_1013670 9210e07b29a9f346bdc5a71ae74782a0 116 Pfam PF11042 Protein of unknown function (DUF2750) 18 115 1.4E-29 T 13-10-2018 IPR021284 Protein of unknown function DUF2750 MADE_1012020 2fcb44378934844b48bdb959fb56d299 171 Gene3D G3DSA:3.90.180.10 14 171 7.2E-33 T 13-10-2018 MADE_1012020 2fcb44378934844b48bdb959fb56d299 171 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 49 144 3.4E-7 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 MADE_1012020 2fcb44378934844b48bdb959fb56d299 171 SUPERFAMILY SSF50129 20 170 7.76E-24 T 13-10-2018 IPR011032 GroES-like superfamily MADE_000001020885 72e3f646ab8350e70a4b92ce2fc795ba 111 Pfam PF05717 IS66 Orf2 like protein 8 105 6.7E-33 T 13-10-2018 IPR008878 Transposase IS66, Orf2 MADE_1011510 72e3f646ab8350e70a4b92ce2fc795ba 111 Pfam PF05717 IS66 Orf2 like protein 8 105 6.7E-33 T 13-10-2018 IPR008878 Transposase IS66, Orf2 MADE_1008225 2a5aa0bbce30b6c7d4ec0bee54d84bcc 483 Pfam PF00665 Integrase core domain 112 241 6.4E-14 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 MADE_1008225 2a5aa0bbce30b6c7d4ec0bee54d84bcc 483 ProDom PD043187 TRANSPOSASE PLASMID CATALYTIC INTEGRASE DNA-BINDING DNA TRANSPOSITION RECOMBINATION FOR INSERTION 8 111 4.0E-33 T 13-10-2018 MADE_1008225 2a5aa0bbce30b6c7d4ec0bee54d84bcc 483 SUPERFAMILY SSF53098 121 249 7.08E-6 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily MADE_1019915 636f04ee74fb22e37e6c37f16b860530 664 SUPERFAMILY SSF53448 129 407 3.56E-19 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019915 636f04ee74fb22e37e6c37f16b860530 664 Gene3D G3DSA:3.90.550.10 125 357 1.1E-15 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1019915 636f04ee74fb22e37e6c37f16b860530 664 Pfam PF13506 Glycosyl transferase family 21 197 375 5.9E-11 T 13-10-2018 IPR025993 Ceramide glucosyltransferase GO:0016757 KEGG: 00600+2.4.1.80|MetaCyc: PWY-5129|MetaCyc: PWY-7836|MetaCyc: PWY-7838|MetaCyc: PWY-7839|MetaCyc: PWY-7841|Reactome: R-HSA-1660662 MADE_1020300 4d562a7c3884acb76e7cacfc3c95aaec 409 Pfam PF13657 HipA N-terminal domain 8 112 5.3E-17 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 MADE_1020300 4d562a7c3884acb76e7cacfc3c95aaec 409 Pfam PF07804 HipA-like C-terminal domain 140 380 1.6E-51 T 13-10-2018 IPR012893 HipA-like, C-terminal MADE_1020300 4d562a7c3884acb76e7cacfc3c95aaec 409 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 8 112 4.2E-14 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 MADE_1020300 4d562a7c3884acb76e7cacfc3c95aaec 409 Gene3D G3DSA:1.10.1070.20 246 364 2.4E-8 T 13-10-2018 MADE_1015650 72077b27c16839cf8e441fd895bc5fe2 454 Pfam PF07690 Major Facilitator Superfamily 3 386 6.1E-41 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1015650 72077b27c16839cf8e441fd895bc5fe2 454 Gene3D G3DSA:1.20.1250.20 236 437 7.7E-12 T 13-10-2018 MADE_1015650 72077b27c16839cf8e441fd895bc5fe2 454 SUPERFAMILY SSF103473 2 435 1.03E-50 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1015650 72077b27c16839cf8e441fd895bc5fe2 454 Gene3D G3DSA:1.20.1250.20 1 170 9.3E-33 T 13-10-2018 MADE_1008360 1c5f19506d47c413c60e78433b5827d4 261 SUPERFAMILY SSF48613 2 252 1.67E-19 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 MADE_1015545 1ade8b4c0778a573fd3eced131ae7230 185 Pfam PF12915 Protein of unknown function (DUF3833) 20 183 7.3E-61 T 13-10-2018 IPR024409 Protein of unknown function DUF3833 MADE_1000405 c290eb08d965d0d7e708413f3fe114c9 142 Pfam PF04143 Sulphur transport 15 133 1.3E-8 T 13-10-2018 IPR007272 Sulphur transport domain MADE_1006485 96510061db5c47d7c20724dac5833e5f 186 SUPERFAMILY SSF47226 4 113 1.07E-17 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_1006485 96510061db5c47d7c20724dac5833e5f 186 Pfam PF01627 Hpt domain 27 105 2.5E-6 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 MADE_1006485 96510061db5c47d7c20724dac5833e5f 186 Gene3D G3DSA:1.20.120.160 4 115 9.0E-19 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 MADE_000001022595 7d593b5e6ea7948f5552b02d05240baf 206 Pfam PF01121 Dephospho-CoA kinase 11 185 3.5E-68 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MADE_000001022595 7d593b5e6ea7948f5552b02d05240baf 206 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 11 194 7.8E-61 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MADE_000001022595 7d593b5e6ea7948f5552b02d05240baf 206 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 9 203 27.466 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 MADE_000001022595 7d593b5e6ea7948f5552b02d05240baf 206 Gene3D G3DSA:3.40.50.300 7 206 3.6E-68 T 13-10-2018 MADE_000001022595 7d593b5e6ea7948f5552b02d05240baf 206 SUPERFAMILY SSF52540 8 202 1.14E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004670 e5394b73f7decf2d76c372da17085910 397 Hamap MF_01262 CCA-adding enzyme [cca]. 1 393 40.119 T 13-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MADE_1004670 e5394b73f7decf2d76c372da17085910 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 2.6E-9 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MADE_1004670 e5394b73f7decf2d76c372da17085910 397 Gene3D G3DSA:3.30.460.10 1 122 2.0E-28 T 13-10-2018 MADE_1004670 e5394b73f7decf2d76c372da17085910 397 PIRSF PIRSF000813 1 397 6.8E-135 T 13-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 MADE_1004670 e5394b73f7decf2d76c372da17085910 397 Gene3D G3DSA:1.10.3090.10 123 395 1.3E-43 T 13-10-2018 MADE_1004670 e5394b73f7decf2d76c372da17085910 397 Pfam PF01743 Poly A polymerase head domain 3 122 5.4E-19 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 MADE_1004670 e5394b73f7decf2d76c372da17085910 397 SUPERFAMILY SSF81301 1 118 1.09E-29 T 13-10-2018 MADE_1004670 e5394b73f7decf2d76c372da17085910 397 SUPERFAMILY SSF81891 120 392 8.89E-45 T 13-10-2018 MADE_1005960 63f1863e98a38fd45386d36ae1e40d48 259 Pfam PF01311 Bacterial export proteins, family 1 14 244 6.8E-64 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MADE_1005960 63f1863e98a38fd45386d36ae1e40d48 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 2.4E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MADE_1005960 63f1863e98a38fd45386d36ae1e40d48 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 21 42 2.4E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MADE_1005960 63f1863e98a38fd45386d36ae1e40d48 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 2.4E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MADE_1005960 63f1863e98a38fd45386d36ae1e40d48 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 80 99 2.4E-17 T 13-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 MADE_1005960 63f1863e98a38fd45386d36ae1e40d48 259 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 13 255 3.3E-68 T 13-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 MADE_1005275 e4a23b4f7cd382df710a30f7b9696ceb 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 435 7.0E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1005275 e4a23b4f7cd382df710a30f7b9696ceb 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 185 205 7.0E-5 T 13-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 MADE_1005275 e4a23b4f7cd382df710a30f7b9696ceb 540 SUPERFAMILY SSF58104 235 536 1.07E-56 T 13-10-2018 MADE_1005275 e4a23b4f7cd382df710a30f7b9696ceb 540 Gene3D G3DSA:1.10.287.950 249 540 3.0E-54 T 13-10-2018 MADE_1005275 e4a23b4f7cd382df710a30f7b9696ceb 540 SMART SM00283 279 539 2.5E-53 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1005275 e4a23b4f7cd382df710a30f7b9696ceb 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 341 504 4.2E-40 T 13-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 MADE_1010110 b883da6ce81f9da818eac6f5ddceaeb7 373 Pfam PF00266 Aminotransferase class-V 17 355 1.9E-35 T 13-10-2018 IPR000192 Aminotransferase class V domain MADE_1010110 b883da6ce81f9da818eac6f5ddceaeb7 373 Gene3D G3DSA:3.90.1150.10 10 369 2.2E-144 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 MADE_1010110 b883da6ce81f9da818eac6f5ddceaeb7 373 SUPERFAMILY SSF53383 11 373 3.3E-102 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase MADE_1010110 b883da6ce81f9da818eac6f5ddceaeb7 373 PIRSF PIRSF000524 5 373 3.5E-111 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 MADE_1010110 b883da6ce81f9da818eac6f5ddceaeb7 373 Gene3D G3DSA:3.40.640.10 23 271 2.2E-144 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 MADE_1010110 b883da6ce81f9da818eac6f5ddceaeb7 373 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 190 210 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site MADE_1007535 4ce8e3f7e7c2149211a45c96287b8df1 417 Pfam PF05159 Capsule polysaccharide biosynthesis protein 134 361 8.8E-18 T 13-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 MADE_1006585 f021c1592b183012f27f9c7e72059bdf 64 Pfam PF04324 BFD-like [2Fe-2S] binding domain 3 51 1.6E-14 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain MADE_1006585 f021c1592b183012f27f9c7e72059bdf 64 Gene3D G3DSA:1.10.10.1100 1 57 7.3E-21 T 13-10-2018 MADE_1012530 0fcf84e51bd3f65600765b39e144364e 148 PIRSF PIRSF004923 1 147 1.1E-35 T 13-10-2018 IPR026268 Protein RseC MADE_1012530 0fcf84e51bd3f65600765b39e144364e 148 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 143 9.5E-27 T 13-10-2018 MADE_1007995 62dc71982b2161ea3e518fe6d7e0d33c 57 Pfam PF06516 Purine nucleoside permease (NUP) 1 48 4.5E-6 T 13-10-2018 IPR009486 Purine nucleoside permease GO:0055085 MADE_1015565 1b4bf9408e5dd88cce12ed670b21e71f 81 Pfam PF14110 Domain of unknown function (DUF4282) 5 78 7.1E-14 T 13-10-2018 IPR025557 Protein of unknown function DUF4282 MADE_1006915 736e8e3843606d9caf7b34c6156c068c 287 Hamap MF_01805 Segregation and condensation protein A [scpA]. 52 283 20.817 T 13-10-2018 IPR003768 Segregation and condensation protein A MADE_1006915 736e8e3843606d9caf7b34c6156c068c 287 Pfam PF02616 Segregation and condensation protein ScpA 69 280 1.0E-29 T 13-10-2018 IPR003768 Segregation and condensation protein A MADE_1014130 75a808e5cc95951939dae5bdee5bc7ba 179 Pfam PF03929 PepSY-associated TM region 11 175 1.6E-16 T 13-10-2018 IPR005625 PepSY-associated TM protein MADE_1007305 3415c71f38becd7c8107e7146d05bcd5 71 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 3 67 4.3E-29 T 13-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor MADE_1007305 3415c71f38becd7c8107e7146d05bcd5 71 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 69 4.0E-21 T 13-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor MADE_000001021700 b8b278d2aa89c40d6a63a1ad1afd337a 375 SUPERFAMILY SSF52402 15 254 5.07E-55 T 13-10-2018 MADE_000001021700 b8b278d2aa89c40d6a63a1ad1afd337a 375 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 16 371 40.602 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MADE_000001021700 b8b278d2aa89c40d6a63a1ad1afd337a 375 Gene3D G3DSA:2.40.30.10 292 374 5.3E-32 T 13-10-2018 MADE_000001021700 b8b278d2aa89c40d6a63a1ad1afd337a 375 Gene3D G3DSA:2.30.30.280 223 291 1.5E-25 T 13-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MADE_000001021700 b8b278d2aa89c40d6a63a1ad1afd337a 375 Gene3D G3DSA:3.40.50.620 3 222 5.4E-96 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_000001021700 b8b278d2aa89c40d6a63a1ad1afd337a 375 Pfam PF03054 tRNA methyl transferase 16 370 1.2E-142 T 13-10-2018 MADE_000001021700 b8b278d2aa89c40d6a63a1ad1afd337a 375 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 16 370 5.3E-154 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 MADE_1009620 9b738dd4bfec685d801c5ba8b1bf8b6c 247 Gene3D G3DSA:3.40.50.150 9 247 1.7E-49 T 13-10-2018 MADE_1009620 9b738dd4bfec685d801c5ba8b1bf8b6c 247 Pfam PF08242 Methyltransferase domain 47 137 1.8E-11 T 13-10-2018 IPR013217 Methyltransferase type 12 MADE_1009620 9b738dd4bfec685d801c5ba8b1bf8b6c 247 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 3 247 35.867 T 13-10-2018 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 MADE_1009620 9b738dd4bfec685d801c5ba8b1bf8b6c 247 SUPERFAMILY SSF53335 3 246 1.88E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase MADE_1006030 6152f353999168150ebc3ec14ff9c0d4 312 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 1.4E-134 T 13-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 MADE_1006030 6152f353999168150ebc3ec14ff9c0d4 312 SUPERFAMILY SSF52317 18 297 2.18E-98 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1006030 6152f353999168150ebc3ec14ff9c0d4 312 PIRSF PIRSF000450 1 309 1.9E-138 T 13-10-2018 IPR033752 MetA family MADE_1006030 6152f353999168150ebc3ec14ff9c0d4 312 Pfam PF04204 Homoserine O-succinyltransferase 2 299 2.8E-131 T 13-10-2018 IPR033752 MetA family MADE_1006030 6152f353999168150ebc3ec14ff9c0d4 312 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 1.0E-112 T 13-10-2018 MADE_1006030 6152f353999168150ebc3ec14ff9c0d4 312 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 299 41.514 T 13-10-2018 IPR033752 MetA family MADE_1006030 6152f353999168150ebc3ec14ff9c0d4 312 Gene3D G3DSA:3.40.50.880 1 301 6.7E-122 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like MADE_1006105 4c4ef5d93a9e650c86221f4024845781 63 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 62 16.747 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MADE_1006105 4c4ef5d93a9e650c86221f4024845781 63 SUPERFAMILY SSF117130 1 54 7.72E-21 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 MADE_1006105 4c4ef5d93a9e650c86221f4024845781 63 Gene3D G3DSA:3.30.70.1680 1 59 1.3E-29 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 MADE_1006105 4c4ef5d93a9e650c86221f4024845781 63 Pfam PF02599 Global regulator protein family 1 52 3.5E-26 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MADE_1006105 4c4ef5d93a9e650c86221f4024845781 63 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 3.0E-11 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MADE_1006105 4c4ef5d93a9e650c86221f4024845781 63 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 55 2.4E-29 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 MADE_1018090 896632a7b7f4006cbcf841925e0cd461 73 SUPERFAMILY SSF89447 2 42 1.38E-6 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily MADE_1018090 896632a7b7f4006cbcf841925e0cd461 73 Gene3D G3DSA:2.10.260.10 1 41 7.9E-7 T 13-10-2018 MADE_1013375 06e67245bd8380aede7c62d5a7c24b16 305 PIRSF PIRSF012524 11 305 1.1E-56 T 13-10-2018 IPR014464 Conserved virulence factor B MADE_1013375 06e67245bd8380aede7c62d5a7c24b16 305 Pfam PF13509 S1 domain 15 92 1.4E-11 T 13-10-2018 IPR039566 Conserved virulence factor B, S1 domain MADE_1013375 06e67245bd8380aede7c62d5a7c24b16 305 Gene3D G3DSA:1.10.10.10 243 304 7.7E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1013375 06e67245bd8380aede7c62d5a7c24b16 305 SUPERFAMILY SSF50249 170 236 1.96E-5 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold MADE_1013375 06e67245bd8380aede7c62d5a7c24b16 305 Gene3D G3DSA:2.40.50.140 175 238 3.2E-5 T 13-10-2018 MADE_1005895 8c32f39cc2af491d1fc5394715a6465d 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 96 109 2.7E-10 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MADE_1005895 8c32f39cc2af491d1fc5394715a6465d 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 40 56 2.7E-10 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MADE_1005895 8c32f39cc2af491d1fc5394715a6465d 111 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 75 91 2.7E-10 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MADE_1005895 8c32f39cc2af491d1fc5394715a6465d 111 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 7 111 15.671 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MADE_1005895 8c32f39cc2af491d1fc5394715a6465d 111 Pfam PF02049 Flagellar hook-basal body complex protein FliE 26 111 4.9E-27 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MADE_1005895 8c32f39cc2af491d1fc5394715a6465d 111 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 6 110 6.6E-18 T 13-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 MADE_1013510 81c4a9c7c002b3a8d92df7168449bfd9 246 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 17 224 3.6E-64 T 13-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 MADE_1013510 81c4a9c7c002b3a8d92df7168449bfd9 246 SUPERFAMILY SSF161098 8 223 2.09E-42 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1013510 81c4a9c7c002b3a8d92df7168449bfd9 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 221 2.3E-20 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 MADE_1013510 81c4a9c7c002b3a8d92df7168449bfd9 246 Gene3D G3DSA:1.10.3720.10 2 227 2.5E-47 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1012385 3cd611f33e9a7396564f98452890c6b6 247 Pfam PF07103 Protein of unknown function (DUF1365) 6 242 2.3E-64 T 13-10-2018 IPR010775 Protein of unknown function DUF1365 MADE_1012430 9ef8adb316b95f39eb41ec263ea9128a 140 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 6 133 1.7E-42 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 MADE_1012430 9ef8adb316b95f39eb41ec263ea9128a 140 SUPERFAMILY SSF48013 3 137 3.53E-39 T 13-10-2018 IPR035926 NusB-like superfamily MADE_1012430 9ef8adb316b95f39eb41ec263ea9128a 140 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 4 135 22.148 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 MADE_1012430 9ef8adb316b95f39eb41ec263ea9128a 140 Pfam PF01029 NusB family 7 132 9.5E-33 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 MADE_1012430 9ef8adb316b95f39eb41ec263ea9128a 140 Gene3D G3DSA:1.10.940.10 1 139 5.1E-47 T 13-10-2018 IPR035926 NusB-like superfamily MADE_1004070 a404291539ef9bb2a617559d655080b9 233 Gene3D G3DSA:1.25.40.10 24 227 1.6E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1004070 a404291539ef9bb2a617559d655080b9 233 SUPERFAMILY SSF48452 77 201 8.67E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1000945 9fcaf024f4df48bdde9169a41cb8934e 204 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 6 200 41.812 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MADE_1000945 9fcaf024f4df48bdde9169a41cb8934e 204 Gene3D G3DSA:3.40.50.10990 7 177 5.0E-69 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MADE_1000945 9fcaf024f4df48bdde9169a41cb8934e 204 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 11 197 3.5E-75 T 13-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MADE_1000945 9fcaf024f4df48bdde9169a41cb8934e 204 SUPERFAMILY SSF142695 9 175 7.32E-61 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MADE_1000945 9fcaf024f4df48bdde9169a41cb8934e 204 Pfam PF00925 GTP cyclohydrolase II 12 173 6.7E-64 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 MADE_1009120 a5c2232ad8358f0c43ff10fab1f9a6c2 280 Pfam PF11750 Protein of unknown function (DUF3307) 19 139 2.1E-27 T 13-10-2018 IPR021737 Bacteriophage phiKZ, Orf197 MADE_000001022345 339dd63ddfd8ab013c0318a472a5f4e5 493 Pfam PF13440 Polysaccharide biosynthesis protein 32 324 3.8E-85 T 13-10-2018 MADE_1001325 6ca182ae1c002171d7e8d477e17141a0 272 Pfam PF00795 Carbon-nitrogen hydrolase 7 256 1.5E-44 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 MADE_1001325 6ca182ae1c002171d7e8d477e17141a0 272 SUPERFAMILY SSF56317 2 264 1.29E-67 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_1001325 6ca182ae1c002171d7e8d477e17141a0 272 Gene3D G3DSA:3.60.110.10 1 270 2.3E-79 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily MADE_1001325 6ca182ae1c002171d7e8d477e17141a0 272 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 152 172 - T 13-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site MADE_1003110 fe3fbb3589805977334dfaffb4c270d1 85 Pfam PF13711 Domain of unknown function (DUF4160) 9 70 4.9E-23 T 13-10-2018 IPR025427 Protein of unknown function DUF4160 MADE_1009075 1b002666262ccc39083e46697ce1cfce 581 Gene3D G3DSA:1.10.3720.10 312 557 9.4E-17 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1009075 1b002666262ccc39083e46697ce1cfce 581 Gene3D G3DSA:1.10.3720.10 7 288 1.7E-15 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1009075 1b002666262ccc39083e46697ce1cfce 581 SUPERFAMILY SSF161098 313 556 9.68E-18 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1009075 1b002666262ccc39083e46697ce1cfce 581 SUPERFAMILY SSF161098 10 279 5.14E-18 T 13-10-2018 IPR035906 MetI-like superfamily MADE_1012135 e9d1faf9916ac6cde3d6bdb89bd661f1 402 Pfam PF04286 Protein of unknown function (DUF445) 16 94 1.3E-10 T 13-10-2018 IPR007383 Protein of unknown function DUF445 MADE_1005835 8bb22e9c6681a2b007541f81bbd24db7 63 Pfam PF05717 IS66 Orf2 like protein 9 58 3.2E-16 T 13-10-2018 IPR008878 Transposase IS66, Orf2 MADE_1001070 66895c580139cfc692a91c29e3fec180 165 Pfam PF11736 Protein of unknown function (DUF3299) 38 163 7.8E-42 T 13-10-2018 IPR021727 Protein of unknown function DUF3299 MADE_1001070 66895c580139cfc692a91c29e3fec180 165 Gene3D G3DSA:2.40.50.870 31 165 2.9E-46 T 13-10-2018 MADE_1001615 3cb7b8ff20b90a94fad0bf7b9a2f8f07 71 SUPERFAMILY SSF46626 3 44 1.59E-5 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1019415 5c5354c434e0d2dc08928111b8f6694d 407 Gene3D G3DSA:1.20.1250.20 184 397 2.8E-45 T 13-10-2018 MADE_1019415 5c5354c434e0d2dc08928111b8f6694d 407 Gene3D G3DSA:1.20.1250.20 1 168 8.6E-34 T 13-10-2018 MADE_1019415 5c5354c434e0d2dc08928111b8f6694d 407 SUPERFAMILY SSF103473 2 392 5.62E-54 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1019415 5c5354c434e0d2dc08928111b8f6694d 407 Pfam PF07690 Major Facilitator Superfamily 3 347 2.2E-31 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1016260 1014412882971076b8b80178234724f2 380 Pfam PF14064 HmuY protein 69 215 4.8E-7 T 13-10-2018 IPR025921 HmuY protein MADE_1001215 7553ce7fd8a8461ea7fd196a568df149 208 Pfam PF05137 Fimbrial assembly protein (PilN) 119 194 1.0E-9 T 13-10-2018 IPR007813 Fimbrial assembly PilN MADE_1008140 f84fe10ed82f98eab1dfbfc09120378e 470 Pfam PF04932 O-Antigen ligase 251 394 1.2E-18 T 13-10-2018 IPR007016 O-antigen ligase-related MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 3 397 5.0E-107 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 Gene3D G3DSA:3.50.50.60 1 192 2.6E-65 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 Gene3D G3DSA:3.50.50.60 258 399 6.9E-32 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 Pfam PF01494 FAD binding domain 3 310 2.3E-28 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 2.3E-15 T 13-10-2018 MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 2.3E-15 T 13-10-2018 MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.3E-15 T 13-10-2018 MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 2.3E-15 T 13-10-2018 MADE_1007160 a8d3ba218f7c3468a41ba20a25fb16f7 399 SUPERFAMILY SSF51905 2 391 3.89E-52 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily MADE_1009125 0ded27cb600797a6dc1cb611628150c7 152 SUPERFAMILY SSF51182 68 138 3.57E-6 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1009125 0ded27cb600797a6dc1cb611628150c7 152 Gene3D G3DSA:2.60.120.10 27 145 1.7E-5 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1009125 0ded27cb600797a6dc1cb611628150c7 152 Pfam PF14499 Domain of unknown function (DUF4437) 32 77 1.5E-13 T 13-10-2018 IPR028013 Protein of unknown function DUF4437 MADE_1012690 6c9230d4e393bdadc4ab445fffd0ae1a 380 Gene3D G3DSA:3.30.200.20 17 140 1.2E-23 T 13-10-2018 MADE_1012690 6c9230d4e393bdadc4ab445fffd0ae1a 380 Gene3D G3DSA:3.90.1200.10 147 376 8.1E-62 T 13-10-2018 MADE_1012690 6c9230d4e393bdadc4ab445fffd0ae1a 380 SUPERFAMILY SSF56112 50 370 1.48E-50 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily MADE_1012690 6c9230d4e393bdadc4ab445fffd0ae1a 380 Pfam PF01636 Phosphotransferase enzyme family 51 294 1.1E-33 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 Gene3D G3DSA:2.30.330.10 40 135 1.4E-33 T 13-10-2018 IPR036429 SpoA-like superfamily MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 SUPERFAMILY SSF101801 53 133 2.49E-24 T 13-10-2018 IPR036429 SpoA-like superfamily MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 53 126 4.2E-33 T 13-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 55 125 7.1E-25 T 13-10-2018 IPR001543 Surface presentation of antigen (SpoA) MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 PRINTS PR00956 Flagellar motor switch protein FliN signature 101 116 1.9E-28 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 PRINTS PR00956 Flagellar motor switch protein FliN signature 88 101 1.9E-28 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 PRINTS PR00956 Flagellar motor switch protein FliN signature 72 88 1.9E-28 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MADE_1005940 89c0af6e2a806af5e26eb6bb7fab5582 135 PRINTS PR00956 Flagellar motor switch protein FliN signature 55 71 1.9E-28 T 13-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 MADE_1002890 7884c95b5764b7e9ba0e3ae19dbc5bb9 180 Pfam PF04314 Copper chaperone PCu(A)C 54 163 1.5E-31 T 13-10-2018 IPR007410 Copper chaperone PCuAC MADE_1002890 7884c95b5764b7e9ba0e3ae19dbc5bb9 180 Gene3D G3DSA:2.60.40.1890 56 174 6.8E-35 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily MADE_1002890 7884c95b5764b7e9ba0e3ae19dbc5bb9 180 SUPERFAMILY SSF110087 51 170 4.97E-40 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily MADE_1019220 78d8e33c322cd5a6e5f23bf83c422040 341 SUPERFAMILY SSF50129 10 152 7.66E-35 T 13-10-2018 IPR011032 GroES-like superfamily MADE_1019220 78d8e33c322cd5a6e5f23bf83c422040 341 Pfam PF16884 N-terminal domain of oxidoreductase 14 123 2.7E-34 T 13-10-2018 MADE_1019220 78d8e33c322cd5a6e5f23bf83c422040 341 SUPERFAMILY SSF51735 133 307 1.92E-46 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily MADE_1019220 78d8e33c322cd5a6e5f23bf83c422040 341 SMART SM00829 28 339 9.7E-8 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 MADE_1019220 78d8e33c322cd5a6e5f23bf83c422040 341 Gene3D G3DSA:3.40.50.720 135 310 7.8E-118 T 13-10-2018 MADE_1019220 78d8e33c322cd5a6e5f23bf83c422040 341 Gene3D G3DSA:3.90.180.10 31 338 7.8E-118 T 13-10-2018 MADE_1019220 78d8e33c322cd5a6e5f23bf83c422040 341 Pfam PF00107 Zinc-binding dehydrogenase 168 289 3.0E-24 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 MADE_1014600 9060de103b14a888f33c951ba2b9794d 371 Pfam PF13252 Protein of unknown function (DUF4043) 40 368 1.1E-50 T 13-10-2018 IPR025267 Protein of unknown function DUF4043 MADE_1014600 9060de103b14a888f33c951ba2b9794d 371 TIGRFAM TIGR04387 capsid_maj_N4: major capsid protein, N4-gp56 family 9 339 1.3E-16 T 13-10-2018 MADE_1001840 c1aee0bd121289707a9b716e7e7ee95d 205 Pfam PF13005 zinc-finger binding domain of transposase IS66 96 139 1.4E-6 T 13-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 MADE_1012995 edd5a74ed3331c74f33c6293346b4736 214 Pfam PF10679 Protein of unknown function (DUF2491) 1 211 1.2E-80 T 13-10-2018 IPR019621 Protein of unknown function DUF2491 MADE_1004795 984b2a7c565adf9cdcd739933e329e50 176 Gene3D G3DSA:1.10.8.640 48 133 3.1E-33 T 13-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily MADE_1004795 984b2a7c565adf9cdcd739933e329e50 176 Pfam PF03918 Cytochrome C biogenesis protein 36 159 1.4E-46 T 13-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family MADE_1004650 1fd4df37e36795701c1d0fbf463a0412 264 Pfam PF11101 Protein of unknown function (DUF2884) 28 256 2.8E-66 T 13-10-2018 IPR021307 Protein of unknown function DUF2884 MADE_1008620 6e9f80edade6fe7e6b086dc1ab4b51a2 269 SUPERFAMILY SSF55486 89 229 5.45E-22 T 13-10-2018 MADE_1008620 6e9f80edade6fe7e6b086dc1ab4b51a2 269 Pfam PF01457 Leishmanolysin 102 230 8.5E-6 T 13-10-2018 IPR001577 Peptidase M8, leishmanolysin GO:0004222|GO:0006508|GO:0007155|GO:0016020 MADE_1008620 6e9f80edade6fe7e6b086dc1ab4b51a2 269 Gene3D G3DSA:3.40.390.10 12 159 3.3E-5 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 MADE_000001023505 b50f6be0b486a343cfec686f5d2d122a 121 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 7 119 2.4E-47 T 13-10-2018 IPR018714 Protein of unknown function DUF2237 MADE_000001023505 b50f6be0b486a343cfec686f5d2d122a 121 Gene3D G3DSA:3.30.56.110 3 121 2.9E-49 T 13-10-2018 MADE_000001021365 09b7f3f86b9bb73b6205e5c09f2e0e20 380 Pfam PF04403 Paraquat-inducible protein A 220 376 1.5E-57 T 13-10-2018 IPR007498 Intermembrane transport protein PqiA-like MADE_000001021365 09b7f3f86b9bb73b6205e5c09f2e0e20 380 Pfam PF04403 Paraquat-inducible protein A 48 195 1.2E-34 T 13-10-2018 IPR007498 Intermembrane transport protein PqiA-like MADE_1010370 93a755215b60ae59fed73422697e51f8 117 Pfam PF01219 Prokaryotic diacylglycerol kinase 16 116 1.7E-35 T 13-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MADE_1010370 93a755215b60ae59fed73422697e51f8 117 Gene3D G3DSA:1.10.3830.10 2 117 2.7E-39 T 13-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 MADE_1002120 84be7a0c157fbdf40edc579ecbff1d1e 255 Pfam PF06439 Domain of Unknown Function (DUF1080) 63 253 9.3E-37 T 13-10-2018 IPR010496 Domain of unknown function DUF1080 MADE_1002120 84be7a0c157fbdf40edc579ecbff1d1e 255 Gene3D G3DSA:2.60.120.560 21 255 1.9E-81 T 13-10-2018 MADE_1013515 302b46808fb9a6df2bba88b32e67486d 462 Pfam PF13531 Bacterial extracellular solute-binding protein 84 347 3.2E-31 T 13-10-2018 MADE_1013515 302b46808fb9a6df2bba88b32e67486d 462 SUPERFAMILY SSF53850 82 347 1.84E-39 T 13-10-2018 MADE_1013515 302b46808fb9a6df2bba88b32e67486d 462 Gene3D G3DSA:3.40.190.10 83 190 7.0E-29 T 13-10-2018 MADE_1013515 302b46808fb9a6df2bba88b32e67486d 462 Gene3D G3DSA:3.40.190.10 337 350 4.8E-22 T 13-10-2018 MADE_1013515 302b46808fb9a6df2bba88b32e67486d 462 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 89 171 1.6E-19 T 13-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 MADE_1013515 302b46808fb9a6df2bba88b32e67486d 462 Gene3D G3DSA:3.40.190.10 228 336 4.8E-22 T 13-10-2018 MADE_000001021775 b4b6564e3c8f0c9b1e757631d31f3da5 279 Pfam PF10977 Protein of unknown function (DUF2797) 40 275 1.7E-92 T 13-10-2018 IPR021246 Protein of unknown function DUF2797 MADE_1001990 77bfcf3d2389d4c3f87ac9098400a1cf 136 Gene3D G3DSA:1.10.443.10 7 96 4.8E-13 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1001990 77bfcf3d2389d4c3f87ac9098400a1cf 136 SUPERFAMILY SSF56349 7 92 2.0E-10 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1019260 2c2736499799d17f88bdac5a3e150fa2 227 Pfam PF02665 Nitrate reductase gamma subunit 6 226 8.8E-78 T 13-10-2018 IPR023234 NarG-like domain MADE_1019260 2c2736499799d17f88bdac5a3e150fa2 227 SUPERFAMILY SSF103501 1 226 1.57E-62 T 13-10-2018 IPR036197 NarG-like superfamily MADE_1019260 2c2736499799d17f88bdac5a3e150fa2 227 Gene3D G3DSA:1.20.950.20 1 218 5.8E-71 T 13-10-2018 MADE_1019260 2c2736499799d17f88bdac5a3e150fa2 227 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 226 2.4E-74 T 13-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 MADE_1001025 a22c38e5e795ad933392beff4713222a 355 Pfam PF13528 Glycosyl transferase family 1 1 301 9.1E-38 T 13-10-2018 MADE_1001025 a22c38e5e795ad933392beff4713222a 355 TIGRFAM TIGR00661 MJ1255: conserved hypothetical protein 2 302 1.4E-71 T 13-10-2018 IPR005262 Conserved hypothetical protein CHP00661 MADE_1001025 a22c38e5e795ad933392beff4713222a 355 SUPERFAMILY SSF53756 10 281 4.32E-8 T 13-10-2018 MADE_1005465 40a895e9c31d790183ee4467aabea799 606 Pfam PF12245 Bacterial Ig-like domain (group 3) 336 358 6.1E-4 T 13-10-2018 IPR022038 Bacterial Ig-like domain MADE_1005465 40a895e9c31d790183ee4467aabea799 606 Pfam PF12245 Bacterial Ig-like domain (group 3) 306 326 0.12 T 13-10-2018 IPR022038 Bacterial Ig-like domain MADE_1005465 40a895e9c31d790183ee4467aabea799 606 Gene3D G3DSA:2.60.40.10 463 566 9.6E-13 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1005465 40a895e9c31d790183ee4467aabea799 606 Gene3D G3DSA:2.60.40.10 274 367 1.4E-13 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1005465 40a895e9c31d790183ee4467aabea799 606 Gene3D G3DSA:2.60.40.10 186 273 8.7E-9 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1005465 40a895e9c31d790183ee4467aabea799 606 Gene3D G3DSA:2.60.40.10 371 459 4.4E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1012180 496152f788c29abbef54bb051503a754 428 Pfam PF13372 Alginate export 30 410 1.0E-42 T 13-10-2018 IPR025388 Alginate export domain MADE_1016510 7deb92aeaa59307efb0b16c12d3fe331 112 SUPERFAMILY SSF50118 4 110 9.59E-29 T 13-10-2018 MADE_1016510 7deb92aeaa59307efb0b16c12d3fe331 112 Gene3D G3DSA:2.30.30.110 1 112 3.6E-36 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor MADE_1016510 7deb92aeaa59307efb0b16c12d3fe331 112 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 10 110 3.8E-21 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 MADE_1004065 e56151987750cb0390f76d6884230923 215 Gene3D G3DSA:1.25.40.10 22 194 3.7E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1004065 e56151987750cb0390f76d6884230923 215 SUPERFAMILY SSF48452 59 179 3.72E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 MADE_1018320 c92dc7eb1eec4972f7ce2fa56b4b659d 110 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 11 99 7.0E-42 T 13-10-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 MADE_1018320 c92dc7eb1eec4972f7ce2fa56b4b659d 110 SUPERFAMILY SSF47598 2 101 6.45E-55 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1018320 c92dc7eb1eec4972f7ce2fa56b4b659d 110 Gene3D G3DSA:1.10.140.10 2 105 3.1E-54 T 13-10-2018 IPR023453 Methionine repressor MetJ domain superfamily MADE_1018320 c92dc7eb1eec4972f7ce2fa56b4b659d 110 Pfam PF01340 Met Apo-repressor, MetJ 3 99 2.7E-58 T 13-10-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 MADE_1002345 6331c2e98c09a532f27ec1bdfd8eb32c 283 SUPERFAMILY SSF75011 63 265 9.68E-8 T 13-10-2018 MADE_1006290 b3a734da1976426074a1837b60d432f5 141 SUPERFAMILY SSF54637 3 118 1.33E-23 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1006290 b3a734da1976426074a1837b60d432f5 141 Pfam PF03061 Thioesterase superfamily 19 92 1.5E-11 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 MADE_1006290 b3a734da1976426074a1837b60d432f5 141 Gene3D G3DSA:3.10.129.10 1 128 2.2E-21 T 13-10-2018 MADE_1002405 68f6994eea0d30b82019915536a173ff 309 Pfam PF05661 Protein of unknown function (DUF808) 5 294 9.5E-105 T 13-10-2018 IPR008526 Inner membrane protein YedI MADE_1002405 68f6994eea0d30b82019915536a173ff 309 PIRSF PIRSF016660 1 308 2.6E-110 T 13-10-2018 IPR008526 Inner membrane protein YedI MADE_1002930 c4f9f9bd31b8705cb984a725664c4bd3 60 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 4 58 2.7E-22 T 13-10-2018 IPR019201 Protein of unknown function DUF2065 MADE_1015435 67b3920fd40b246907df08c3a959c289 259 Pfam PF03883 Peroxide stress protein YaaA 1 243 3.0E-93 T 13-10-2018 IPR005583 Peroxide stress protein YaaA MADE_1015435 67b3920fd40b246907df08c3a959c289 259 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 37.397 T 13-10-2018 IPR005583 Peroxide stress protein YaaA MADE_1001750 e2d6209e740b38d45c48d8c16a657700 525 Pfam PF03050 Transposase IS66 family 172 459 9.4E-76 T 13-10-2018 IPR004291 Transposase, IS66 MADE_1001750 e2d6209e740b38d45c48d8c16a657700 525 Pfam PF13817 IS66 C-terminal element 466 502 4.3E-11 T 13-10-2018 IPR039552 Transposase IS66, C-terminal MADE_1001750 e2d6209e740b38d45c48d8c16a657700 525 Pfam PF13007 Transposase C of IS166 homeodomain 27 86 5.8E-10 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain MADE_1001935 ec9bf3f43cf29dfaa58a7aa9361f90a5 221 Gene3D G3DSA:1.20.120.1630 6 208 2.0E-23 T 13-10-2018 MADE_1001935 ec9bf3f43cf29dfaa58a7aa9361f90a5 221 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 102 186 9.5E-8 T 13-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 MADE_1013105 d2c2ed055253c8c1465b28cd0154ec5c 229 Pfam PF02698 DUF218 domain 60 221 1.1E-20 T 13-10-2018 IPR003848 Domain of unknown function DUF218 MADE_1010790 da8653f1dbd4ea3b4005d06b87f8dbb4 104 Gene3D G3DSA:3.10.450.160 17 104 6.0E-8 T 13-10-2018 MADE_1006865 b16539ace6c4965891df15207cf61fdf 154 Gene3D G3DSA:2.30.110.10 2 139 1.5E-32 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_1006865 b16539ace6c4965891df15207cf61fdf 154 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 6 139 3.9E-29 T 13-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain MADE_1006865 b16539ace6c4965891df15207cf61fdf 154 SUPERFAMILY SSF50475 5 128 6.14E-22 T 13-10-2018 MADE_1015360 3c7e98d1668512abee67fd6e0d1b060d 178 Pfam PF02325 YGGT family 10 76 1.0E-17 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 MADE_1015360 3c7e98d1668512abee67fd6e0d1b060d 178 Pfam PF02325 YGGT family 106 171 2.1E-20 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 MADE_000001022930 4789e6a3b56a35a7bdf421773c9e62fc 73 Pfam PF09905 DNA-binding protein VF530 5 67 1.4E-35 T 13-10-2018 IPR018668 DNA-binding protein VF530-like GO:0003677 MADE_000001022930 4789e6a3b56a35a7bdf421773c9e62fc 73 Gene3D G3DSA:1.10.720.30 13 71 7.9E-31 T 13-10-2018 IPR036361 SAP domain superfamily MADE_1012060 ad7406d04b146f216887fa70bd1ad531 97 Pfam PF08891 YfcL protein 15 95 8.4E-28 T 13-10-2018 IPR014987 Uncharacterised protein family YfcL MADE_1003555 33fcdb98c1db6bfb337408ffde41f8ef 146 Pfam PF06853 Protein of unknown function (DUF1249) 27 139 1.0E-40 T 13-10-2018 IPR009659 Protein of unknown function DUF1249 MADE_1007180 01c0f178307bcaca4f1637df45d8a6c8 183 Gene3D G3DSA:1.20.1290.10 13 181 8.6E-32 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MADE_1007180 01c0f178307bcaca4f1637df45d8a6c8 183 SUPERFAMILY SSF69118 1 180 1.68E-43 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 MADE_1018970 cacaaa57168c909988420bca5371bf20 446 Pfam PF12704 MacB-like periplasmic core domain 18 205 1.1E-10 T 13-10-2018 IPR025857 MacB-like periplasmic core domain MADE_1018970 cacaaa57168c909988420bca5371bf20 446 Pfam PF02687 FtsX-like permease family 346 434 4.1E-7 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MADE_1019495 0002c5c5bdbe9171eb81b5f255d8609b 382 Pfam PF00144 Beta-lactamase 39 361 7.8E-45 T 13-10-2018 IPR001466 Beta-lactamase-related MADE_1019495 0002c5c5bdbe9171eb81b5f255d8609b 382 Gene3D G3DSA:3.40.710.10 31 373 1.6E-61 T 13-10-2018 MADE_1019495 0002c5c5bdbe9171eb81b5f255d8609b 382 SUPERFAMILY SSF56601 39 376 1.11E-62 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like MADE_1019705 ec049357534eac993b0fd9c60fc2aa3b 209 Gene3D G3DSA:2.30.110.10 6 204 1.9E-38 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 MADE_1019705 ec049357534eac993b0fd9c60fc2aa3b 209 Pfam PF01613 Flavin reductase like domain 32 164 4.6E-15 T 13-10-2018 IPR002563 Flavin reductase like domain GO:0010181 MADE_1019705 ec049357534eac993b0fd9c60fc2aa3b 209 SUPERFAMILY SSF50475 22 192 1.28E-27 T 13-10-2018 MADE_1008170 da3b715ea643f784284d9fbbda047e97 440 Pfam PF04932 O-Antigen ligase 209 361 2.2E-10 T 13-10-2018 IPR007016 O-antigen ligase-related MADE_1006610 4f0f01b8707a05352d42c0e5f99c76c8 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 13-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MADE_1006610 4f0f01b8707a05352d42c0e5f99c76c8 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 130 1.7E-61 T 13-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 MADE_1006610 4f0f01b8707a05352d42c0e5f99c76c8 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 4.1E-21 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain MADE_1006610 4f0f01b8707a05352d42c0e5f99c76c8 135 SUPERFAMILY SSF54593 1 127 5.24E-34 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1006610 4f0f01b8707a05352d42c0e5f99c76c8 135 Gene3D G3DSA:3.10.180.10 1 135 4.4E-47 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1016405 da92013ad73e06b9630241daa2e020ed 483 Pfam PF07012 Curlin associated repeat 293 323 1.4E-4 T 13-10-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 MADE_1016405 da92013ad73e06b9630241daa2e020ed 483 Pfam PF07012 Curlin associated repeat 200 233 4.9E-6 T 13-10-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 MADE_1016405 da92013ad73e06b9630241daa2e020ed 483 Pfam PF07012 Curlin associated repeat 177 211 9.8E-7 T 13-10-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 MADE_1016405 da92013ad73e06b9630241daa2e020ed 483 Pfam PF07012 Curlin associated repeat 222 255 1.3E-4 T 13-10-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 MADE_1003840 21aa8c0b05c8f7e9320db22076ac194b 324 Pfam PF04381 Putative exonuclease, RdgC 22 318 6.7E-96 T 13-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 MADE_000001021595 bd527fa2c093ab19ebbe2ef7db15d338 132 Pfam PF12514 Protein of unknown function (DUF3718) 34 100 3.8E-21 T 13-10-2018 IPR022193 Protein of unknown function DUF3718 MADE_1011590 d80b6b149312224dd6a3d6225afe3f60 217 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 83 186 6.0E-13 T 13-10-2018 MADE_1011590 d80b6b149312224dd6a3d6225afe3f60 217 SUPERFAMILY SSF109604 7 189 1.57E-26 T 13-10-2018 MADE_1011590 d80b6b149312224dd6a3d6225afe3f60 217 Gene3D G3DSA:1.10.3210.10 2 201 1.5E-60 T 13-10-2018 MADE_1011590 d80b6b149312224dd6a3d6225afe3f60 217 Pfam PF12917 HD containing hydrolase-like enzyme 14 190 3.7E-9 T 13-10-2018 IPR027366 HD containing hydrolase-like enzyme MADE_1008545 12d9ce10d9756bc7f3c30bc56efc5220 83 Pfam PF09834 Predicted membrane protein (DUF2061) 1 52 1.4E-22 T 13-10-2018 IPR018638 Domain of unknown function DUF2061, membrane MADE_1016680 7830d176fd5479aab428049e97710fca 154 SMART SM00360 73 145 4.6E-16 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 MADE_1016680 7830d176fd5479aab428049e97710fca 154 SUPERFAMILY SSF54928 65 150 1.48E-21 T 13-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 MADE_1016680 7830d176fd5479aab428049e97710fca 154 Gene3D G3DSA:3.30.70.330 53 154 3.9E-23 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily MADE_1016680 7830d176fd5479aab428049e97710fca 154 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 74 143 6.7E-14 T 13-10-2018 IPR000504 RNA recognition motif domain GO:0003676 MADE_1001980 bf39840191afb8e4c37552663dce8382 176 Pfam PF03713 Domain of unknown function (DUF305) 92 153 3.2E-9 T 13-10-2018 IPR005183 Domain of unknown function DUF305 MADE_1001980 bf39840191afb8e4c37552663dce8382 176 Gene3D G3DSA:1.20.1260.10 83 172 1.5E-9 T 13-10-2018 IPR012347 Ferritin-like MADE_1000920 5c12a4818cfcc5ee29cb2908f14e0bbc 247 Gene3D G3DSA:3.40.30.10 10 78 5.3E-11 T 13-10-2018 MADE_1000920 5c12a4818cfcc5ee29cb2908f14e0bbc 247 SUPERFAMILY SSF52833 3 77 2.07E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1000920 5c12a4818cfcc5ee29cb2908f14e0bbc 247 Pfam PF00462 Glutaredoxin 17 67 1.1E-5 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 MADE_1007965 bda2d5dbb9e2eef014e9736826cb7b6d 336 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 11 329 1.4E-110 T 13-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 MADE_1007965 bda2d5dbb9e2eef014e9736826cb7b6d 336 Hamap MF_01962 Adenine deaminase. 6 318 78.255 T 13-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 MADE_1007965 bda2d5dbb9e2eef014e9736826cb7b6d 336 Gene3D G3DSA:3.20.20.140 2 333 2.1E-103 T 13-10-2018 MADE_1007965 bda2d5dbb9e2eef014e9736826cb7b6d 336 Pfam PF00962 Adenosine/AMP deaminase 9 327 2.7E-73 T 13-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 MADE_1007965 bda2d5dbb9e2eef014e9736826cb7b6d 336 SUPERFAMILY SSF51556 6 330 2.07E-85 T 13-10-2018 IPR032466 Metal-dependent hydrolase MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 PRINTS PR00075 Fatty acid desaturase family 1 signature 58 78 2.9E-35 T 13-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 PRINTS PR00075 Fatty acid desaturase family 1 signature 155 173 2.9E-35 T 13-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 PRINTS PR00075 Fatty acid desaturase family 1 signature 186 207 2.9E-35 T 13-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 PRINTS PR00075 Fatty acid desaturase family 1 signature 229 243 2.9E-35 T 13-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 PRINTS PR00075 Fatty acid desaturase family 1 signature 96 125 2.9E-35 T 13-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 PRINTS PR00075 Fatty acid desaturase family 1 signature 35 57 2.9E-35 T 13-10-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 Pfam PF00487 Fatty acid desaturase 40 261 2.1E-25 T 13-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 MADE_1016700 a4b0a96585458828d28321b0cbb77972 375 PIRSF PIRSF000345 8 338 2.0E-101 T 13-10-2018 IPR009160 Acyl-CoA desaturase, haem/steroid binding domain-containing GO:0004768|GO:0006636|GO:0016021 MetaCyc: PWY-5987|MetaCyc: PWY-5996 MADE_1004100 ad36d10c76c9203a390f019828c3a0d2 225 Pfam PF09335 SNARE associated Golgi protein 72 188 8.9E-18 T 13-10-2018 IPR032816 SNARE associated Golgi protein MADE_1020390 d3e8cdde43e8aba5edf9b31c95575037 73 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 16 62 6.1E-15 T 13-10-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 MADE_1010780 c413d01e147fe8a6f75a939bf34d6954 90 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 21 80 8.4E-12 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 MADE_1010780 c413d01e147fe8a6f75a939bf34d6954 90 Gene3D G3DSA:3.10.20.30 1 89 6.1E-19 T 13-10-2018 IPR012675 Beta-grasp domain superfamily MADE_1010780 c413d01e147fe8a6f75a939bf34d6954 90 SUPERFAMILY SSF54292 17 88 5.51E-20 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 MADE_1010780 c413d01e147fe8a6f75a939bf34d6954 90 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 41 49 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 MADE_1009145 47b58ab5da9a52c222eb25420c8974a5 436 Pfam PF12040 Domain of unknown function (DUF3526) 278 424 5.2E-30 T 13-10-2018 IPR021913 Protein of unknown function DUF3526 MADE_000001022530 345d9c7145aaea031f7554bc61256f52 248 Pfam PF12705 PD-(D/E)XK nuclease superfamily 29 239 6.0E-13 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type MADE_000001022855 648cb3cea55b817f335e32b0c8f9e33d 269 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 50 248 1.4E-54 T 13-10-2018 IPR014547 Uncharacterised conserved protein UCP028477 MADE_1016530 1c1c12c8128c1aa2b9855e6fa932b984 267 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 46 259 4.0E-44 T 13-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related MADE_1008520 64bfd4c44e409a59951213fb30888fce 303 SUPERFAMILY SSF55073 157 272 3.53E-24 T 13-10-2018 IPR029787 Nucleotide cyclase MADE_1008520 64bfd4c44e409a59951213fb30888fce 303 SMART SM00267 138 303 2.8E-15 T 13-10-2018 IPR000160 GGDEF domain MADE_1008520 64bfd4c44e409a59951213fb30888fce 303 Pfam PF00990 Diguanylate cyclase, GGDEF domain 153 288 7.2E-27 T 13-10-2018 IPR000160 GGDEF domain MADE_1008520 64bfd4c44e409a59951213fb30888fce 303 Gene3D G3DSA:3.30.70.270 137 302 1.5E-28 T 13-10-2018 MADE_1008520 64bfd4c44e409a59951213fb30888fce 303 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 153 267 2.5E-23 T 13-10-2018 IPR000160 GGDEF domain MADE_1000120 10827db4778ab9a09e5546b94ca64813 158 Pfam PF04361 Protein of unknown function (DUF494) 1 158 7.4E-62 T 13-10-2018 IPR007456 Smg MADE_1000120 10827db4778ab9a09e5546b94ca64813 158 Hamap MF_00598 Protein Smg [smg]. 1 158 32.211 T 13-10-2018 IPR007456 Smg MADE_1016280 ffc97a682eba4d8af1218e32eaf8b7e3 287 Pfam PF03151 Triose-phosphate Transporter family 94 229 8.8E-8 T 13-10-2018 IPR004853 Sugar phosphate transporter domain MADE_1016280 ffc97a682eba4d8af1218e32eaf8b7e3 287 SUPERFAMILY SSF103481 181 281 3.47E-5 T 13-10-2018 MADE_1013210 752ae6a1c3d7bea975c946ee57260842 439 Pfam PF04932 O-Antigen ligase 205 356 4.5E-17 T 13-10-2018 IPR007016 O-antigen ligase-related MADE_1015575 7b1f93dc868df2aae5656578a9ffaa70 270 Pfam PF04116 Fatty acid hydroxylase superfamily 79 212 2.6E-29 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MADE_1002075 79c69c6a383bcfb9ce96387c6b742838 107 Pfam PF11872 Protein of unknown function (DUF3392) 2 104 5.2E-35 T 13-10-2018 IPR021813 Protein of unknown function DUF3392 MADE_1001470 496d8e0ada14acafe8aacfd9812d751a 114 Gene3D G3DSA:3.40.50.2020 7 111 1.8E-5 T 13-10-2018 MADE_1016450 06f3ff3cf7fcc5ccc3c69855fc1ad99e 139 SUPERFAMILY SSF53850 18 126 5.07E-7 T 13-10-2018 MADE_000001023245 cac7757df887e32e1152352fdfca897f 114 Pfam PF01850 PIN domain 13 105 4.6E-9 T 13-10-2018 IPR002716 PIN domain MADE_000001023245 cac7757df887e32e1152352fdfca897f 114 SUPERFAMILY SSF88723 12 111 2.8E-16 T 13-10-2018 IPR029060 PIN-like domain superfamily MADE_000001023245 cac7757df887e32e1152352fdfca897f 114 Gene3D G3DSA:3.40.50.1010 1 111 1.4E-8 T 13-10-2018 MADE_1001620 322ae320f538900e100e58543cdc602f 60 SUPERFAMILY SSF46626 3 59 1.83E-8 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1001620 322ae320f538900e100e58543cdc602f 60 Gene3D G3DSA:1.10.760.10 1 60 7.2E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 MADE_1001260 6683b0a1fed645388ebd0c07c10847b2 195 SUPERFAMILY SSF54523 8 105 2.12E-14 T 13-10-2018 MADE_1001260 6683b0a1fed645388ebd0c07c10847b2 195 Pfam PF07963 Prokaryotic N-terminal methylation motif 3 28 9.3E-9 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001260 6683b0a1fed645388ebd0c07c10847b2 195 Gene3D G3DSA:3.30.700.10 8 154 2.2E-15 T 13-10-2018 MADE_1001260 6683b0a1fed645388ebd0c07c10847b2 195 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1001260 6683b0a1fed645388ebd0c07c10847b2 195 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 28 6.7E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 45 62 2.0E-60 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 121 141 2.0E-60 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 62 82 2.0E-60 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 100 120 2.0E-60 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 156 182 2.0E-60 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 204 228 2.0E-60 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 Pfam PF01578 Cytochrome C assembly protein 26 184 1.9E-30 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 MADE_1004770 49d359cdd231c36b05edcad2a846131a 260 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 45 228 3.6E-79 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 MADE_000001022160 771ea72595d64cfce44a84222c5bc95e 318 Pfam PF12762 ISXO2-like transposase domain 142 299 1.7E-20 T 13-10-2018 IPR024445 ISXO2-like transposase domain MADE_000001022160 771ea72595d64cfce44a84222c5bc95e 318 SMART SM01126 142 299 1.2E-45 T 13-10-2018 IPR024445 ISXO2-like transposase domain MADE_1015115 fb8f7b95240d334b7ce021c9f8515d3b 292 Gene3D G3DSA:2.70.70.10 131 291 8.5E-47 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1015115 fb8f7b95240d334b7ce021c9f8515d3b 292 SUPERFAMILY SSF51261 159 288 5.02E-54 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1015115 fb8f7b95240d334b7ce021c9f8515d3b 292 Pfam PF01551 Peptidase family M23 191 285 1.3E-30 T 13-10-2018 IPR016047 Peptidase M23 MADE_1020195 a00e424c9f16d66cdf84ea501ba2c4eb 145 SUPERFAMILY SSF54637 7 140 1.46E-37 T 13-10-2018 IPR029069 HotDog domain superfamily MADE_1020195 a00e424c9f16d66cdf84ea501ba2c4eb 145 Pfam PF13279 Thioesterase-like superfamily 20 137 1.4E-13 T 13-10-2018 MADE_1020195 a00e424c9f16d66cdf84ea501ba2c4eb 145 Gene3D G3DSA:3.10.129.10 2 142 4.9E-44 T 13-10-2018 MADE_1009410 6fcde6bbb4aa5bb8239c4e2b8f32e2b6 349 SUPERFAMILY SSF52540 53 167 7.49E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1009410 6fcde6bbb4aa5bb8239c4e2b8f32e2b6 349 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 26 319 2.0E-76 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MADE_1009410 6fcde6bbb4aa5bb8239c4e2b8f32e2b6 349 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 8 332 36.187 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MADE_1009410 6fcde6bbb4aa5bb8239c4e2b8f32e2b6 349 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 330 1.2E-98 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 MADE_1004120 4f367350a2889d0a9dbd34266e872f34 119 Pfam PF13473 Cupredoxin-like domain 9 109 9.3E-25 T 13-10-2018 IPR028096 EfeO-type cupredoxin-like domain MADE_1004120 4f367350a2889d0a9dbd34266e872f34 119 Gene3D G3DSA:2.60.40.420 17 110 4.0E-20 T 13-10-2018 IPR008972 Cupredoxin MADE_1004120 4f367350a2889d0a9dbd34266e872f34 119 SUPERFAMILY SSF49503 13 110 1.31E-16 T 13-10-2018 IPR008972 Cupredoxin MADE_1002910 901c1e77944c4a3d4b30b57732f8e610 110 Pfam PF06127 Protein of unknown function (DUF962) 11 105 5.1E-38 T 13-10-2018 IPR009305 Protein of unknown function DUF962 MADE_1007430 f9e04a9c6ba36a77fad3cfb4592b70e3 301 Pfam PF03994 Domain of Unknown Function (DUF350) 93 145 1.1E-5 T 13-10-2018 IPR007140 Protein of unknown function DUF350 MADE_1015060 2dc68a43bc47f84207cbae4d575a487e 244 SUPERFAMILY SSF52540 1 244 7.75E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1015060 2dc68a43bc47f84207cbae4d575a487e 244 Pfam PF13614 AAA domain 1 162 5.5E-26 T 13-10-2018 IPR025669 AAA domain MADE_1015060 2dc68a43bc47f84207cbae4d575a487e 244 Gene3D G3DSA:3.40.50.300 1 244 8.0E-49 T 13-10-2018 MADE_1011030 38e358b721a592f21fb1cfd3540c26d8 115 PIRSF PIRSF039032 1 110 9.1E-39 T 13-10-2018 IPR009387 Toxin HigB-2 MADE_1011030 38e358b721a592f21fb1cfd3540c26d8 115 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 45 109 2.0E-6 T 13-10-2018 IPR009387 Toxin HigB-2 MADE_1012090 a66f2336e0769c8144d4652cb33d9338 405 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 303 314 - T 13-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 MADE_1012090 a66f2336e0769c8144d4652cb33d9338 405 SUPERFAMILY SSF50630 288 391 1.16E-10 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_1012090 a66f2336e0769c8144d4652cb33d9338 405 Pfam PF13975 gag-polyprotein putative aspartyl protease 298 386 3.5E-17 T 13-10-2018 MADE_1012090 a66f2336e0769c8144d4652cb33d9338 405 Gene3D G3DSA:2.40.70.10 275 403 4.0E-22 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily MADE_1011765 c0bc5644b2b2e6ec6ae0115fe598865d 197 Pfam PF09347 Domain of unknown function (DUF1989) 4 168 8.7E-50 T 13-10-2018 IPR018959 Protein of unknown function DUF1989 MADE_1016610 d4d796a494d8e6ee5e0a3f8e95bf75a8 198 Pfam PF13505 Outer membrane protein beta-barrel domain 18 198 4.0E-24 T 13-10-2018 IPR027385 Outer membrane protein beta-barrel MADE_1016610 d4d796a494d8e6ee5e0a3f8e95bf75a8 198 SUPERFAMILY SSF56925 34 198 1.02E-31 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MADE_1016610 d4d796a494d8e6ee5e0a3f8e95bf75a8 198 Gene3D G3DSA:2.40.160.20 23 198 1.5E-31 T 13-10-2018 MADE_1005575 6ff63df455a20b88af6293151c33ed72 349 Gene3D G3DSA:1.20.5.340 130 254 3.9E-5 T 13-10-2018 MADE_1005575 6ff63df455a20b88af6293151c33ed72 349 Pfam PF11740 Plasmid replication region DNA-binding N-term 7 115 8.9E-25 T 13-10-2018 IPR021104 KfrA, N-terminal DNA-binding domain MADE_000001021070 9214ce3897990f361c8b9552563fd301 216 Pfam PF03458 UPF0126 domain 8 80 5.5E-19 T 13-10-2018 IPR005115 Uncharacterised domain UPF0126 MADE_000001021070 9214ce3897990f361c8b9552563fd301 216 Pfam PF03458 UPF0126 domain 94 166 7.9E-17 T 13-10-2018 IPR005115 Uncharacterised domain UPF0126 MADE_1018055 3fe409a47eea86725f3b567bba8b7d49 93 Pfam PF13670 Peptidase propeptide and YPEB domain 8 91 1.2E-26 T 13-10-2018 IPR025711 PepSY domain MADE_1018055 3fe409a47eea86725f3b567bba8b7d49 93 SUPERFAMILY SSF54593 23 83 5.4E-5 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase MADE_1010890 7d89bb0a7a1584803b60cce7434806e2 238 Pfam PF11306 Protein of unknown function (DUF3108) 15 225 4.3E-15 T 13-10-2018 IPR021457 Protein of unknown function DUF3108 MADE_1018240 41c124d5e95b8c7575c39b95da2759e1 316 Gene3D G3DSA:3.40.50.410 141 314 2.5E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1018240 41c124d5e95b8c7575c39b95da2759e1 316 SUPERFAMILY SSF53300 148 310 2.09E-8 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily MADE_1006225 67126cdd02b0c18fe1605d74213d8642 376 SMART SM00702 176 359 1.8E-30 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 MADE_1006225 67126cdd02b0c18fe1605d74213d8642 376 Gene3D G3DSA:2.60.120.620 168 360 3.1E-44 T 13-10-2018 MADE_1006225 67126cdd02b0c18fe1605d74213d8642 376 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 258 359 1.5E-15 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 MADE_1006820 b09d82d5a2afea2cce9100ff1b54b562 218 Gene3D G3DSA:3.40.50.1110 33 217 1.6E-62 T 13-10-2018 IPR036514 SGNH hydrolase superfamily MADE_1006820 b09d82d5a2afea2cce9100ff1b54b562 218 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 198 1.4E-20 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain MADE_1006820 b09d82d5a2afea2cce9100ff1b54b562 218 SUPERFAMILY SSF52266 37 213 2.68E-46 T 13-10-2018 MADE_1000880 7fcdc233528b95f1c729e9db946ad7e1 105 Pfam PF00893 Small Multidrug Resistance protein 2 94 3.0E-24 T 13-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 MADE_1000880 7fcdc233528b95f1c729e9db946ad7e1 105 SUPERFAMILY SSF103481 4 103 2.35E-17 T 13-10-2018 MADE_1000880 7fcdc233528b95f1c729e9db946ad7e1 105 Gene3D G3DSA:1.10.3730.20 1 105 1.3E-27 T 13-10-2018 MADE_1020425 f30304171454d7b52d67b4121547707e 112 Gene3D G3DSA:1.10.10.10 2 107 1.2E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1020425 f30304171454d7b52d67b4121547707e 112 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 7 85 1.7E-14 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 MADE_1020425 f30304171454d7b52d67b4121547707e 112 SUPERFAMILY SSF46767 5 86 8.5E-14 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 MADE_1003665 d6a4fc48bf0bba00f60f27e792e48430 230 SUPERFAMILY SSF48317 28 225 2.35E-35 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily MADE_1003665 d6a4fc48bf0bba00f60f27e792e48430 230 Gene3D G3DSA:1.20.144.10 129 229 4.9E-20 T 13-10-2018 MADE_1003665 d6a4fc48bf0bba00f60f27e792e48430 230 Pfam PF01569 PAP2 superfamily 103 222 3.7E-25 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MADE_1003665 d6a4fc48bf0bba00f60f27e792e48430 230 SMART SM00014 101 215 1.5E-16 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase MADE_1008330 d5e745497b2c151e0d35d8da0e8eb5c7 471 Pfam PF12704 MacB-like periplasmic core domain 32 273 8.7E-13 T 13-10-2018 IPR025857 MacB-like periplasmic core domain MADE_1008330 d5e745497b2c151e0d35d8da0e8eb5c7 471 Pfam PF02687 FtsX-like permease family 364 464 2.0E-11 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MADE_1004230 c67269bbc6e29a22af274a747793aacd 157 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 151 2.1E-53 T 13-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 MADE_1004230 c67269bbc6e29a22af274a747793aacd 157 Pfam PF02470 MlaD protein 38 117 6.4E-19 T 13-10-2018 IPR003399 Mce/MlaD MADE_1000130 bfd8a3a4a36fd5443468c1db42c7c307 201 Gene3D G3DSA:3.90.870.10 15 200 1.9E-56 T 13-10-2018 MADE_1000130 bfd8a3a4a36fd5443468c1db42c7c307 201 SUPERFAMILY SSF55821 20 197 2.08E-49 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily MADE_1000130 bfd8a3a4a36fd5443468c1db42c7c307 201 Pfam PF01300 Telomere recombination 29 200 2.8E-39 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 MADE_1000130 bfd8a3a4a36fd5443468c1db42c7c307 201 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 19 200 37.983 T 13-10-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 MADE_000001021530 2d1c77cf7aa483be1ba4b2d63c165f27 384 SUPERFAMILY SSF103473 26 379 8.24E-15 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_000001021530 2d1c77cf7aa483be1ba4b2d63c165f27 384 Gene3D G3DSA:1.20.1250.20 25 379 1.2E-9 T 13-10-2018 MADE_1009020 3f072d85f4861bb22e42fa79ec9c0f8f 192 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 16 190 4.5E-35 T 13-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 MADE_1003215 e806ca9ffcd4f4087745e2370a7057ac 137 Gene3D G3DSA:1.10.260.40 3 67 1.4E-10 T 13-10-2018 MADE_1003215 e806ca9ffcd4f4087745e2370a7057ac 137 Pfam PF01381 Helix-turn-helix 10 62 2.7E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1003215 e806ca9ffcd4f4087745e2370a7057ac 137 SMART SM00530 9 63 1.3E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1003215 e806ca9ffcd4f4087745e2370a7057ac 137 SUPERFAMILY SSF47413 7 65 5.36E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1006205 39117721c76b9e24f141612cdeed2ba2 93 Pfam PF10719 Late competence development protein ComFB 8 84 1.1E-21 T 13-10-2018 IPR019657 Late competence development protein ComFB MADE_1003995 5e68ba1a39035191ed24b6495bb74206 750 Pfam PF03968 OstA-like protein 59 187 3.3E-11 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal MADE_1003995 5e68ba1a39035191ed24b6495bb74206 750 Pfam PF04453 Organic solvent tolerance protein 299 659 5.9E-93 T 13-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 MADE_1003995 5e68ba1a39035191ed24b6495bb74206 750 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 3 728 19.726 T 13-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 MADE_1003225 7bb5a63e90303d1234a2aac156f62f90 151 Pfam PF15428 Immunity protein 26 8 95 7.6E-6 T 13-10-2018 IPR029278 Immunity protein 26 MADE_1008985 a56da6ab75c94059345c345d68164d50 442 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 21 437 3.6E-52 T 13-10-2018 IPR018721 Protein of unknown function DUF2252 MADE_1003055 21aa698261a3f8a88463c4d09f779141 87 Gene3D G3DSA:3.10.450.530 1 83 2.2E-15 T 13-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily MADE_1003055 21aa698261a3f8a88463c4d09f779141 87 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 6 81 3.6E-26 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system MADE_1000385 5a8a94e540bf8f54c3c2a98439e18bfc 96 SUPERFAMILY SSF47413 7 62 5.63E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 MADE_1000385 5a8a94e540bf8f54c3c2a98439e18bfc 96 SMART SM00530 14 67 5.4E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1000385 5a8a94e540bf8f54c3c2a98439e18bfc 96 Gene3D G3DSA:1.10.260.40 2 72 4.5E-13 T 13-10-2018 MADE_1000385 5a8a94e540bf8f54c3c2a98439e18bfc 96 Pfam PF01381 Helix-turn-helix 16 61 9.4E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 MADE_1001985 f4e7e185f0411e378ea97953bad0ce08 131 Gene3D G3DSA:1.10.287.70 28 131 1.2E-11 T 13-10-2018 MADE_1001985 f4e7e185f0411e378ea97953bad0ce08 131 Pfam PF07885 Ion channel 57 129 6.4E-11 T 13-10-2018 IPR013099 Potassium channel domain MADE_1001985 f4e7e185f0411e378ea97953bad0ce08 131 SUPERFAMILY SSF81324 75 129 3.14E-10 T 13-10-2018 MADE_1000335 d28fd97471007cf8c777ddc20f03796f 137 Pfam PF03748 Flagellar basal body-associated protein FliL 32 135 8.1E-18 T 13-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 MADE_1020075 1cc825cbabc478589781731e78da9c01 179 SUPERFAMILY SSF52833 54 159 2.24E-5 T 13-10-2018 IPR036249 Thioredoxin-like superfamily MADE_1008595 177cbcea7313b9285539ea69498f6ee3 270 Pfam PF03618 Kinase/pyrophosphorylase 5 260 5.0E-76 T 13-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 MADE_1008595 177cbcea7313b9285539ea69498f6ee3 270 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 1 269 76.631 T 13-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein MADE_1009690 8ae25e3dfc9a65624c18b8df53d42193 305 SUPERFAMILY SSF51261 99 297 7.46E-49 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1009690 8ae25e3dfc9a65624c18b8df53d42193 305 Pfam PF01551 Peptidase family M23 200 294 1.1E-27 T 13-10-2018 IPR016047 Peptidase M23 MADE_1009690 8ae25e3dfc9a65624c18b8df53d42193 305 Gene3D G3DSA:2.70.70.10 146 300 1.2E-40 T 13-10-2018 IPR011055 Duplicated hybrid motif MADE_1003070 1c849956192aba9af3d41210b9133bc0 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 11 76 2.0E-9 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM MADE_1003070 1c849956192aba9af3d41210b9133bc0 82 SUPERFAMILY SSF143120 12 67 3.92E-8 T 13-10-2018 IPR036165 YefM-like superfamily MADE_1003070 1c849956192aba9af3d41210b9133bc0 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 12 61 5.7E-6 T 13-10-2018 MADE_000001021575 820cf4387cd330cf6e442a7288d3ee43 446 Pfam PF04996 Succinylarginine dihydrolase 3 444 1.2E-226 T 13-10-2018 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 MADE_000001021575 820cf4387cd330cf6e442a7288d3ee43 446 TIGRFAM TIGR03241 arg_catab_astB: succinylarginine dihydrolase 4 444 3.3E-224 T 13-10-2018 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 MADE_000001021575 820cf4387cd330cf6e442a7288d3ee43 446 Hamap MF_01172 N-succinylarginine dihydrolase [astB]. 1 445 59.965 T 13-10-2018 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 MADE_000001021575 820cf4387cd330cf6e442a7288d3ee43 446 SUPERFAMILY SSF55909 3 445 6.96E-210 T 13-10-2018 MADE_000001021575 820cf4387cd330cf6e442a7288d3ee43 446 Gene3D G3DSA:3.75.10.20 1 446 3.5E-207 T 13-10-2018 IPR037031 Succinylarginine dihydrolase superfamily GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 MADE_000001021460 e446ef477946cb6689f351974481b8ee 104 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 91 2.4E-14 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family MADE_000001021460 e446ef477946cb6689f351974481b8ee 104 Gene3D G3DSA:3.30.2310.20 1 96 1.9E-22 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily MADE_1010470 ab23448503d0e04d1f9995cbb58c4181 317 Pfam PF01171 PP-loop family 50 212 5.8E-15 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 MADE_1010470 ab23448503d0e04d1f9995cbb58c4181 317 SUPERFAMILY SSF52402 26 244 1.37E-55 T 13-10-2018 MADE_1010470 ab23448503d0e04d1f9995cbb58c4181 317 Gene3D G3DSA:3.40.50.620 8 275 4.7E-50 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold MADE_1010470 ab23448503d0e04d1f9995cbb58c4181 317 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 19 280 57.591 T 13-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 MADE_1010470 ab23448503d0e04d1f9995cbb58c4181 317 PIRSF PIRSF004976 2 278 7.4E-77 T 13-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 MADE_1007955 5977605d3d388eebfbed86c9f8658825 85 Gene3D G3DSA:2.60.460.20 18 83 7.3E-5 T 13-10-2018 MADE_1013540 bbb7c39e980a2ff1d0f0c198feb737fb 256 Gene3D G3DSA:3.40.50.720 5 256 2.5E-80 T 13-10-2018 MADE_1013540 bbb7c39e980a2ff1d0f0c198feb737fb 256 Pfam PF00899 ThiF family 13 251 4.7E-58 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 MADE_1013540 bbb7c39e980a2ff1d0f0c198feb737fb 256 SUPERFAMILY SSF69572 5 254 5.36E-77 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 MADE_1007470 351206d7d312c5f1d9a69d83e121022b 519 SUPERFAMILY SSF57997 168 300 1.11E-5 T 13-10-2018 MADE_1007470 351206d7d312c5f1d9a69d83e121022b 519 TIGRFAM TIGR03007 pepcterm_ChnLen: polysaccharide chain length determinant protein, PEP-CTERM locus subfamily 13 506 4.4E-144 T 13-10-2018 IPR014345 PEP-CTERM locus polysaccharide chain length determinant MADE_1003005 973d885796ffdce309d429724d15d417 372 SUPERFAMILY SSF56935 21 315 1.6E-17 T 13-10-2018 MADE_1010920 c9111454b76b4b16df76c1a154dabd0e 290 SUPERFAMILY SSF52540 38 256 5.74E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1010920 c9111454b76b4b16df76c1a154dabd0e 290 Gene3D G3DSA:3.40.50.300 16 289 2.4E-75 T 13-10-2018 MADE_1004925 4950f1ea01f54fdc58d8ab07638a7bb6 100 Pfam PF11743 Protein of unknown function (DUF3301) 7 97 4.8E-27 T 13-10-2018 IPR021732 Protein of unknown function DUF3301 MADE_1014850 47bc0b1162767f9501425074272a987a 388 Pfam PF13203 Putative metallopeptidase domain 5 251 2.3E-42 T 13-10-2018 IPR025154 Putative metallopeptidase domain MADE_1014850 47bc0b1162767f9501425074272a987a 388 Pfam PF09967 VWA-like domain (DUF2201) 260 386 1.4E-24 T 13-10-2018 IPR018698 VWA-like domain MADE_000001021560 5b2ff889c3f2b85bcf7436a652880e24 408 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 3 407 9.3E-117 T 13-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 MADE_000001021560 5b2ff889c3f2b85bcf7436a652880e24 408 Pfam PF12704 MacB-like periplasmic core domain 27 230 3.1E-9 T 13-10-2018 IPR025857 MacB-like periplasmic core domain MADE_000001021560 5b2ff889c3f2b85bcf7436a652880e24 408 Pfam PF02687 FtsX-like permease family 297 403 1.2E-7 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MADE_1019635 3c540c0296fff406e18f65889570f4d7 178 Pfam PF04186 FxsA cytoplasmic membrane protein 6 113 1.2E-36 T 13-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 MADE_000001021335 d99d08232fc660b9caedd6a806ba9038 162 Gene3D G3DSA:3.40.630.30 1 160 9.0E-52 T 13-10-2018 MADE_000001021335 d99d08232fc660b9caedd6a806ba9038 162 Pfam PF00583 Acetyltransferase (GNAT) family 33 138 9.6E-21 T 13-10-2018 IPR000182 GNAT domain MADE_000001021335 d99d08232fc660b9caedd6a806ba9038 162 SUPERFAMILY SSF55729 5 157 4.56E-41 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1004105 aba46f9e594344bbbb50b7aca945fae7 245 SUPERFAMILY SSF53448 5 234 6.75E-42 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1004105 aba46f9e594344bbbb50b7aca945fae7 245 Pfam PF00535 Glycosyl transferase family 2 7 163 3.0E-24 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1004105 aba46f9e594344bbbb50b7aca945fae7 245 Gene3D G3DSA:3.90.550.10 2 235 6.9E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1014240 206fa792dddec8d667bcb17c922c1ebe 150 Pfam PF11215 Protein of unknown function (DUF3010) 1 135 1.8E-55 T 13-10-2018 IPR021378 Protein of unknown function DUF3010 MADE_1006690 19907ce4e8014bcb68c4fbc6748fc4d0 306 Gene3D G3DSA:3.40.190.10 124 224 5.4E-6 T 13-10-2018 MADE_1006690 19907ce4e8014bcb68c4fbc6748fc4d0 306 SUPERFAMILY SSF53850 56 261 5.1E-14 T 13-10-2018 MADE_1006690 19907ce4e8014bcb68c4fbc6748fc4d0 306 Gene3D G3DSA:3.40.190.10 58 259 5.4E-6 T 13-10-2018 MADE_1012985 59dae8d2d41ed7481ee6fe6a040422ef 226 Pfam PF04012 PspA/IM30 family 2 222 1.5E-37 T 13-10-2018 IPR007157 PspA/IM30 MADE_1010225 297e8e1f9092172208c0ca6419142012 435 Pfam PF10011 Predicted membrane protein (DUF2254) 19 388 3.4E-88 T 13-10-2018 IPR018723 Protein of unknown function DUF2254, membrane MADE_1020250 1e393d3c6a99f3e013b987bdcfcac0bb 195 Pfam PF09335 SNARE associated Golgi protein 53 159 1.4E-15 T 13-10-2018 IPR032816 SNARE associated Golgi protein MADE_1020080 d48c12b938c023fb97284ac7d9ef0e90 234 Pfam PF02104 SURF1 family 18 216 2.8E-30 T 13-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 MADE_1001505 552981a9e2dff42324484ecf8cf6c859 314 Pfam PF01435 Peptidase family M48 116 212 1.9E-11 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 MADE_1001505 552981a9e2dff42324484ecf8cf6c859 314 Gene3D G3DSA:3.30.2010.10 111 192 1.7E-6 T 13-10-2018 MADE_1020355 49533806c7e031bf101a2045974ccb92 580 Pfam PF06048 Domain of unknown function (DUF927) 28 310 2.1E-98 T 13-10-2018 IPR009270 Domain of unknown function DUF927 MADE_1009895 bee95734be0dad2eb6673f2e9e9acea7 249 Pfam PF01609 Transposase DDE domain 85 242 5.6E-16 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1009895 bee95734be0dad2eb6673f2e9e9acea7 249 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 2 73 1.7E-24 T 13-10-2018 IPR025161 Putative transposase IS4/IS5 family MADE_1015810 4c9049c2cf62d43f6ab49a1d8f787042 314 Pfam PF03186 CobD/Cbib protein 16 284 1.8E-24 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 MADE_1003740 ca7901ccaba1d79645d43064d239f5ed 406 Pfam PF13372 Alginate export 61 258 5.8E-11 T 13-10-2018 IPR025388 Alginate export domain MADE_1018375 ea36e594f17395bcb5b10fe18591395e 326 PIRSF PIRSF003097 21 322 4.4E-68 T 13-10-2018 IPR004513 Cell division protein FtsX GO:0016021 MADE_1001035 de2a83aac48e171855c361a924b06c73 161 Pfam PF03737 Aldolase/RraA 7 152 2.4E-34 T 13-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein MADE_1001035 de2a83aac48e171855c361a924b06c73 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 1.4E-58 T 13-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 MADE_1001035 de2a83aac48e171855c361a924b06c73 161 SUPERFAMILY SSF89562 2 158 2.62E-43 T 13-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily MADE_1001035 de2a83aac48e171855c361a924b06c73 161 Gene3D G3DSA:3.50.30.40 1 161 1.4E-54 T 13-10-2018 MADE_1001035 de2a83aac48e171855c361a924b06c73 161 Hamap MF_00471 Regulator of ribonuclease activity A [rraA]. 1 161 44.635 T 13-10-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 MADE_1001035 de2a83aac48e171855c361a924b06c73 161 TIGRFAM TIGR02998 RraA_entero: regulator of ribonuclease activity A 1 160 1.4E-77 T 13-10-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 MADE_1000380 b8e4a4dbf54d97998ab4e9defc9251b4 397 Pfam PF13657 HipA N-terminal domain 20 113 3.0E-5 T 13-10-2018 IPR017508 HipA, N-terminal subdomain 1 MADE_1000380 b8e4a4dbf54d97998ab4e9defc9251b4 397 Pfam PF07804 HipA-like C-terminal domain 160 374 5.4E-44 T 13-10-2018 IPR012893 HipA-like, C-terminal MADE_1004530 f1ed171cf2e6890a55f1049f794c08b6 115 Pfam PF03567 Sulfotransferase family 4 98 1.3E-5 T 13-10-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 MADE_1004530 f1ed171cf2e6890a55f1049f794c08b6 115 SUPERFAMILY SSF52540 7 104 4.09E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004615 50ae3ad8336da792d946273d730a3907 253 Pfam PF04397 LytTr DNA-binding domain 161 245 1.4E-14 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MADE_1004615 50ae3ad8336da792d946273d730a3907 253 Gene3D G3DSA:2.40.50.40 150 218 3.9E-9 T 13-10-2018 MADE_1004615 50ae3ad8336da792d946273d730a3907 253 SMART SM00850 158 251 1.8E-9 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 MADE_1018280 18d7deadac4341a7568d1bcc949c3de0 151 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 8 144 4.9E-60 T 13-10-2018 IPR021679 Toxin endonuclease, YhaV GO:0004540|GO:0110001 MADE_1013150 b379e03728ad5b128b9f938b9e6ba11f 321 Gene3D G3DSA:3.90.550.10 1 204 1.1E-33 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013150 b379e03728ad5b128b9f938b9e6ba11f 321 SUPERFAMILY SSF53448 5 265 6.43E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases MADE_1013150 b379e03728ad5b128b9f938b9e6ba11f 321 Pfam PF00535 Glycosyl transferase family 2 6 127 9.7E-17 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 MADE_1004685 d1134f66da8c93b8fb18cfc92f7bdc69 395 SUPERFAMILY SSF109604 140 310 7.99E-26 T 13-10-2018 MADE_1004685 d1134f66da8c93b8fb18cfc92f7bdc69 395 SMART SM00471 146 282 5.1E-4 T 13-10-2018 IPR003607 HD/PDEase domain MADE_1004685 d1134f66da8c93b8fb18cfc92f7bdc69 395 Gene3D G3DSA:1.10.3210.10 4 312 1.1E-66 T 13-10-2018 MADE_1004685 d1134f66da8c93b8fb18cfc92f7bdc69 395 Pfam PF13487 HD domain 203 263 1.3E-13 T 13-10-2018 MADE_1004685 d1134f66da8c93b8fb18cfc92f7bdc69 395 Pfam PF11871 Domain of unknown function (DUF3391) 2 118 1.0E-14 T 13-10-2018 IPR021812 Protein of unknown function DUF3391 MADE_1004270 05fe89525fad7736a45727cfd4076667 365 Hamap MF_01919 Cell division protein ZapE [zapE]. 1 365 54.158 T 13-10-2018 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 MADE_1004270 05fe89525fad7736a45727cfd4076667 365 Gene3D G3DSA:3.40.50.300 4 191 9.4E-20 T 13-10-2018 MADE_1004270 05fe89525fad7736a45727cfd4076667 365 SUPERFAMILY SSF52540 60 223 8.89E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1004270 05fe89525fad7736a45727cfd4076667 365 Pfam PF03969 AFG1-like ATPase 1 361 1.6E-146 T 13-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 MADE_1010450 d627e877bb980dfe8c3321550d38d464 76 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 4.0E-14 T 13-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type MADE_1010450 d627e877bb980dfe8c3321550d38d464 76 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 3.9E-20 T 13-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type MADE_1010390 538d6b225aa3a6465aa0efca43558f8e 543 PIRSF PIRSF006429 6 530 3.4E-158 T 13-10-2018 IPR024188 Glutamate synthase large subunit-like protein MADE_1010390 538d6b225aa3a6465aa0efca43558f8e 543 SUPERFAMILY SSF51395 9 497 8.37E-131 T 13-10-2018 MADE_1010390 538d6b225aa3a6465aa0efca43558f8e 543 PIRSF PIRSF500060 6 526 5.6E-213 T 13-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria MADE_1010390 538d6b225aa3a6465aa0efca43558f8e 543 Gene3D G3DSA:3.20.20.70 126 497 8.4E-107 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 MADE_1010390 538d6b225aa3a6465aa0efca43558f8e 543 Pfam PF01645 Conserved region in glutamate synthase 152 470 1.9E-89 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 MADE_1010640 8e0a99394aed28e5614efd9a4817ee4d 151 Pfam PF07681 DoxX 18 105 4.9E-21 T 13-10-2018 IPR032808 DoxX family MADE_1003820 75316cae64e2c451c278da953b6360d6 564 Pfam PF03571 Peptidase family M49 155 394 3.1E-14 T 13-10-2018 IPR039461 Peptidase family M49 MADE_1003820 75316cae64e2c451c278da953b6360d6 564 Gene3D G3DSA:1.20.120.1470 154 282 8.4E-6 T 13-10-2018 MADE_1016320 7fcd49a91258f547c1e9eadfcd2e298d 567 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 43 529 1.2E-73 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 MADE_1006715 f4c73dc8121b1c50f80bd7ed0dc97c6e 234 Pfam PF04893 Yip1 domain 14 224 4.9E-18 T 13-10-2018 IPR006977 Yip1 domain GO:0016020 MADE_1000140 5a06d987e89bc6b301b91e2c75749994 224 Pfam PF03922 OmpW family 24 224 1.8E-59 T 13-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 MADE_1000140 5a06d987e89bc6b301b91e2c75749994 224 Gene3D G3DSA:2.40.160.20 23 224 5.8E-72 T 13-10-2018 MADE_1000140 5a06d987e89bc6b301b91e2c75749994 224 SUPERFAMILY SSF56925 24 224 9.42E-30 T 13-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel MADE_1008950 82fb7822526a40bed9eaef9974f1da6a 269 Gene3D G3DSA:1.20.5.340 162 255 5.9E-5 T 13-10-2018 MADE_1008950 82fb7822526a40bed9eaef9974f1da6a 269 SUPERFAMILY SSF57997 79 248 3.53E-5 T 13-10-2018 MADE_1019205 e22ee6c3243e0574490cc49f482f038d 147 Pfam PF11026 Protein of unknown function (DUF2721) 15 141 5.4E-37 T 13-10-2018 IPR021279 Protein of unknown function DUF2721 MADE_1011760 7cd789f591a85e5ec1fd93ab51ad9911 224 Pfam PF08892 YqcI/YcgG family 12 217 5.5E-62 T 13-10-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG MADE_1003415 54ab249605f8c962c4dab38c47a9b7b2 55 Gene3D G3DSA:1.10.287.130 1 51 9.9E-7 T 13-10-2018 MADE_1003415 54ab249605f8c962c4dab38c47a9b7b2 55 SUPERFAMILY SSF47384 4 38 8.44E-6 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_1013115 e83100d54904c7833d80b13f6506c955 88 Pfam PF03050 Transposase IS66 family 2 37 6.4E-10 T 13-10-2018 IPR004291 Transposase, IS66 MADE_1001210 87e5cef17140c83f5c42eb096a1bf021 304 SUPERFAMILY SSF53067 55 149 2.07E-6 T 13-10-2018 MADE_1008475 4b766e3ff7872bfa7b9e110bc2ac7010 551 Pfam PF03961 Flagellar Assembly Protein A 84 544 5.5E-116 T 13-10-2018 IPR005646 Flagellar assembly protein A MADE_1001115 dc5f951c130b514e671bd66c750c59a7 287 Gene3D G3DSA:3.40.50.1820 53 287 6.7E-17 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1001115 dc5f951c130b514e671bd66c750c59a7 287 SUPERFAMILY SSF53474 22 284 7.75E-20 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1009465 f65d92979a8ee38f7cce5fccb7d54d4b 140 Pfam PF11911 Protein of unknown function (DUF3429) 2 136 7.0E-26 T 13-10-2018 IPR021836 Protein of unknown function DUF3429 MADE_1012980 547fec14e140a6b948f1a3b2bf75d759 129 Pfam PF09938 Uncharacterized protein conserved in bacteria (DUF2170) 12 128 6.3E-38 T 13-10-2018 IPR019231 Protein of unknown function DUF2170 MADE_1002545 c05bd54cc1cd1d611fa3876f23281bef 66 Pfam PF11174 Protein of unknown function (DUF2970) 7 60 1.4E-20 T 13-10-2018 IPR021344 Protein of unknown function DUF2970 MADE_1010420 352d5cae42f9f94707f11fa1d8ddb47b 53 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 3 45 8.3E-14 T 13-10-2018 IPR008621 Cbb3-type cytochrome oxidase component MADE_1000260 6ae56221e5f28694520b6095ef14306d 700 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 35 693 5.6E-233 T 13-10-2018 IPR010344 Exopolysaccharide biosynthesis protein YbjH MADE_1001395 2998dd4ad863feb4aace85e69fbce657 365 Pfam PF04245 37-kD nucleoid-associated bacterial protein 82 312 2.6E-13 T 13-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 MADE_1016090 25d169b4a0b6662ccf012f96fe001b0b 244 Pfam PF10099 Anti-sigma-K factor rskA 62 236 2.0E-21 T 13-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 MADE_1003395 2f6fa0d7506f205b00cf2fe603b07635 571 TIGRFAM TIGR03545 TIGR03545: TIGR03545 family protein 14 520 1.5E-100 T 13-10-2018 IPR019934 Conserved hypothetical protein CHP03545 MADE_1006860 7156106fc13ddd652a5762cdfebe7658 89 Pfam PF13670 Peptidase propeptide and YPEB domain 12 83 3.9E-6 T 13-10-2018 IPR025711 PepSY domain MADE_1004930 ef019daacc8c66c29291003e805876d3 349 Pfam PF12069 Protein of unknown function (DUF3549) 4 344 3.9E-97 T 13-10-2018 IPR021936 Protein of unknown function DUF3549 MADE_1008505 3a5058e561d145d785677fe33442f8a9 348 Pfam PF00149 Calcineurin-like phosphoesterase 63 269 2.7E-14 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 MADE_1008505 3a5058e561d145d785677fe33442f8a9 348 SUPERFAMILY SSF56300 62 338 9.59E-51 T 13-10-2018 MADE_1008505 3a5058e561d145d785677fe33442f8a9 348 PIRSF PIRSF000898 17 347 1.0E-80 T 13-10-2018 IPR024927 Purple acid phosphatase GO:0003993 KEGG: 00730+3.1.3.2|KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348|Reactome: R-HSA-196843 MADE_1008505 3a5058e561d145d785677fe33442f8a9 348 Gene3D G3DSA:3.60.21.10 55 346 4.3E-84 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like MADE_000001022310 1f3db1a07a1d3f4e67f99cf4715fb43f 535 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 114 244 2.4E-7 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MADE_1010650 5b1e64030a1eb25d6c8e062677bd1c1d 488 Pfam PF11840 Protein of unknown function (DUF3360) 3 483 7.4E-248 T 13-10-2018 IPR021794 Protein of unknown function DUF3360 MADE_1011475 4bba8fc6e78d05e4c75b37e3e51aadd2 141 Pfam PF04138 GtrA-like protein 12 127 3.3E-20 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 MADE_1003085 8dc5b8b6ff43079e4e157aaa4bd3522b 72 Pfam PF09720 Putative addiction module component 14 67 1.2E-12 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module MADE_1004285 c9606507a75f5d2b5948fe738c1e28de 315 Pfam PF11231 Protein of unknown function (DUF3034) 28 312 2.4E-97 T 13-10-2018 IPR021393 Protein of unknown function DUF3034 MADE_000001021590 7e7dfbf6e922eab624f31e378827a709 132 Pfam PF12514 Protein of unknown function (DUF3718) 34 102 1.6E-23 T 13-10-2018 IPR022193 Protein of unknown function DUF3718 MADE_1020520 de6e9164498df1c0c2936bb29d2a6c40 222 Gene3D G3DSA:1.10.8.1180 114 183 5.6E-13 T 13-10-2018 MADE_1016745 34e03fdb80e9f83f88dd65333fe197df 251 TIGRFAM TIGR04219 OMP_w_GlyGly: outer membrane protein 4 251 7.1E-84 T 13-10-2018 IPR026387 Outer membrane protein MADE_1008540 43106bddd640ce704a41c9778d36886a 100 Pfam PF07238 PilZ domain 7 98 1.4E-13 T 13-10-2018 IPR009875 PilZ domain GO:0035438 MADE_1008540 43106bddd640ce704a41c9778d36886a 100 SUPERFAMILY SSF141371 2 96 4.9E-11 T 13-10-2018 MADE_1008540 43106bddd640ce704a41c9778d36886a 100 Gene3D G3DSA:2.40.10.220 4 100 1.3E-11 T 13-10-2018 MADE_1000205 d866063dbe8856867aa3daa688059a58 583 Pfam PF05960 Bacterial protein of unknown function (DUF885) 43 573 9.8E-167 T 13-10-2018 IPR010281 Protein of unknown function DUF885 MADE_1018060 4a1298932a345f5c9b4781e529b999cb 189 SUPERFAMILY SSF81342 8 188 7.06E-30 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 MADE_1018060 4a1298932a345f5c9b4781e529b999cb 189 Gene3D G3DSA:1.20.950.20 1 175 6.0E-11 T 13-10-2018 MADE_1018060 4a1298932a345f5c9b4781e529b999cb 189 Pfam PF01292 Prokaryotic cytochrome b561 14 185 4.4E-24 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 MADE_1006025 2f0235cd64d5aac94ac10143e43edd89 144 Pfam PF10975 Protein of unknown function (DUF2802) 77 141 1.3E-20 T 13-10-2018 IPR021244 Protein of unknown function DUF2802 MADE_1007405 4f16f63e01308569d3bb31c1669ec97f 85 Pfam PF11280 Protein of unknown function (DUF3081) 5 81 3.7E-31 T 13-10-2018 IPR021432 Protein of unknown function DUF3081 MADE_1005930 b8f8bfa333b9bfda4b44f2123a0072fe 179 Pfam PF03748 Flagellar basal body-associated protein FliL 78 179 1.1E-19 T 13-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 MADE_000001021360 9f2c8e806e4ba4065c7cdf68f44b548e 550 Pfam PF02470 MlaD protein 46 134 1.3E-11 T 13-10-2018 IPR003399 Mce/MlaD MADE_000001021360 9f2c8e806e4ba4065c7cdf68f44b548e 550 Pfam PF02470 MlaD protein 293 392 9.7E-12 T 13-10-2018 IPR003399 Mce/MlaD MADE_1014935 386a887dc437c9e815f70ac3fb50d428 98 Pfam PF06945 Protein of unknown function (DUF1289) 18 64 6.5E-16 T 13-10-2018 IPR010710 Protein of unknown function DUF1289 MADE_1016480 49b3e058387aee45e89c71d5933e875f 118 Pfam PF08302 Fungal tRNA ligase phosphodiesterase domain 47 99 2.4E-6 T 13-10-2018 IPR015965 tRNA ligase, phosphodiesterase GO:0003972|GO:0005524|GO:0006388 MADE_1015825 d170820bbbea199159cc01b00d10d08a 133 Pfam PF11026 Protein of unknown function (DUF2721) 6 118 1.0E-32 T 13-10-2018 IPR021279 Protein of unknown function DUF2721 MADE_1007835 32d468d4741eeddcdc7c53f98d8a3708 358 Pfam PF01734 Patatin-like phospholipase 62 242 3.4E-7 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 MADE_1007835 32d468d4741eeddcdc7c53f98d8a3708 358 SUPERFAMILY SSF52151 33 318 1.15E-13 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase MADE_1010520 2efb25ab5d0793f407495109db101769 230 SMART SM01144 21 213 7.2E-63 T 13-10-2018 IPR005636 DTW MADE_1010520 2efb25ab5d0793f407495109db101769 230 Pfam PF03942 DTW domain 24 206 1.3E-38 T 13-10-2018 IPR005636 DTW MADE_1003670 6cc71d23d64256f0b9a256fd7f088ed2 209 Pfam PF06042 Nucleotidyltransferase 24 207 5.5E-52 T 13-10-2018 IPR009267 Putative nucleotidyltransferase MADE_000001022745 f15ce3ce9815369ee549071d29accd59 136 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 134 2.5E-32 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 MADE_000001022745 f15ce3ce9815369ee549071d29accd59 136 Gene3D G3DSA:3.30.420.270 62 130 7.5E-9 T 13-10-2018 MADE_1011500 8195db85fd6b2932e73dee89bde54326 344 Pfam PF01757 Acyltransferase family 1 294 3.7E-23 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MADE_1003035 d7b9ad7e219179a521232d4f9014f379 140 Gene3D G3DSA:3.40.630.30 3 138 8.3E-12 T 13-10-2018 MADE_1003035 d7b9ad7e219179a521232d4f9014f379 140 SUPERFAMILY SSF55729 9 133 3.61E-13 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase MADE_1009740 597afaf11df05de2126e18dd3837eba8 367 Pfam PF13808 DDE_Tnp_1-associated 5 91 2.5E-25 T 13-10-2018 IPR032806 H repeat-associated protein, N-terminal MADE_1009740 597afaf11df05de2126e18dd3837eba8 367 Pfam PF01609 Transposase DDE domain 98 337 1.2E-21 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 MADE_1019615 0386f625b4059fbcc40351ba6aaa5d99 269 Pfam PF11185 Protein of unknown function (DUF2971) 63 175 2.2E-4 T 13-10-2018 IPR021352 Protein of unknown function DUF2971 MADE_1006500 26425745f1db92ae361bd8615d8ad0d3 212 SUPERFAMILY SSF53955 25 175 6.29E-26 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily MADE_1006500 26425745f1db92ae361bd8615d8ad0d3 212 Gene3D G3DSA:1.10.530.10 42 198 4.3E-13 T 13-10-2018 MADE_1011775 54cb4f45fc971f48551e1403b59fe8f9 624 Pfam PF05787 Bacterial protein of unknown function (DUF839) 243 615 2.3E-27 T 13-10-2018 IPR008557 Protein of unknown function DUF839 MADE_1000210 d32e63fb2f4ea7d052ace5869d4a4b9b 111 Pfam PF08850 Domain of unknown function (DUF1820) 7 103 3.7E-40 T 13-10-2018 IPR014949 Protein of unknown function DUF1820 MADE_1010785 038c03a0cf33eb1f3552cc2a7055bdaa 80 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 4 77 1.0E-27 T 13-10-2018 IPR018680 Protein of unknown function DUF2164 MADE_1010985 e26da32239a5c47dd6e2b075b0da52bd 346 Pfam PF01548 Transposase 9 157 1.2E-13 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 MADE_1010985 e26da32239a5c47dd6e2b075b0da52bd 346 Pfam PF02371 Transposase IS116/IS110/IS902 family 227 299 4.8E-20 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 MADE_1003450 dd8d5c19ac8eb906ab5a11eef3f1fa9a 268 Pfam PF01925 Sulfite exporter TauE/SafE 12 263 1.3E-48 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MADE_000001022850 8001d07fafc83b102a293b08170e4eb4 156 Pfam PF05360 yiaA/B two helix domain 11 63 4.5E-22 T 13-10-2018 IPR008024 YiaAB two helix MADE_000001022850 8001d07fafc83b102a293b08170e4eb4 156 Pfam PF05360 yiaA/B two helix domain 74 126 1.1E-17 T 13-10-2018 IPR008024 YiaAB two helix MADE_1004680 0ed912722797521942edcfe0adb5a9fd 415 Pfam PF16537 Type II secretion system protein B 352 410 2.7E-23 T 13-10-2018 IPR032389 Type II secretion system protein B MADE_1004680 0ed912722797521942edcfe0adb5a9fd 415 Pfam PF11871 Domain of unknown function (DUF3391) 5 74 2.8E-7 T 13-10-2018 IPR021812 Protein of unknown function DUF3391 MADE_1010120 36a82c437244019e5c322d4830dd40e7 151 Gene3D G3DSA:3.30.450.40 1 151 3.4E-65 T 13-10-2018 IPR029016 GAF-like domain superfamily MADE_1010120 36a82c437244019e5c322d4830dd40e7 151 SUPERFAMILY SSF55781 5 146 4.58E-43 T 13-10-2018 MADE_1010120 36a82c437244019e5c322d4830dd40e7 151 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 89 106 - T 13-10-2018 IPR000614 Free Met sulfoxide reductase conserved site MADE_1010120 36a82c437244019e5c322d4830dd40e7 151 Pfam PF13185 GAF domain 30 145 1.1E-9 T 13-10-2018 IPR003018 GAF domain GO:0005515 MADE_1000045 48f9a62da38a62ce000baca1c389cf8b 202 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 15 193 3.6E-74 T 13-10-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 MADE_1000045 48f9a62da38a62ce000baca1c389cf8b 202 Pfam PF03352 Methyladenine glycosylase 18 192 3.3E-77 T 13-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 MADE_1000045 48f9a62da38a62ce000baca1c389cf8b 202 Gene3D G3DSA:1.10.340.30 13 197 1.8E-81 T 13-10-2018 MADE_1000045 48f9a62da38a62ce000baca1c389cf8b 202 SUPERFAMILY SSF48150 14 195 1.33E-77 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 MADE_1004620 02c159da91426783f68f95fd5076aff3 137 Pfam PF03788 LrgA family 19 110 8.2E-21 T 13-10-2018 IPR005538 LrgA/CidA family GO:0016021 MADE_1004095 7b71aead64f31908fa2234adcace5668 603 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 64 224 2.9E-15 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like MADE_1018115 06a1b59b550d7a27cb6fe7175fdc995b 457 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 427 9.6E-153 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MADE_1018115 06a1b59b550d7a27cb6fe7175fdc995b 457 PIRSF PIRSF006446 1 454 1.8E-170 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 MADE_1004915 5a87da44743fbba5d08e6dcf554807ac 121 Pfam PF11399 Protein of unknown function (DUF3192) 17 118 1.4E-39 T 13-10-2018 IPR021534 Protein of unknown function DUF3192 MADE_1020265 6b9d4e141fdb91432f78275c5b1f5d5e 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 195 264 1.1E-21 T 13-10-2018 IPR009597 Domain of unknown function DUF1206 MADE_1020265 6b9d4e141fdb91432f78275c5b1f5d5e 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 101 169 8.2E-9 T 13-10-2018 IPR009597 Domain of unknown function DUF1206 MADE_1020265 6b9d4e141fdb91432f78275c5b1f5d5e 267 Pfam PF06724 Domain of Unknown Function (DUF1206) 14 79 1.2E-11 T 13-10-2018 IPR009597 Domain of unknown function DUF1206 MADE_1011540 66a819e6cc04b741c9019cce7fe079fb 201 Pfam PF06055 Exopolysaccharide synthesis, ExoD 14 191 5.4E-43 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD MADE_1011540 66a819e6cc04b741c9019cce7fe079fb 201 PIRSF PIRSF033239 1 200 3.5E-46 T 13-10-2018 IPR010331 Exopolysaccharide synthesis, ExoD MADE_1008315 24a4dabf261838d3a4ad4d2e558621b5 509 Pfam PF10972 Peptidoglycan-binding protein, CsiV 17 500 5.4E-50 T 13-10-2018 IPR021241 Peptidoglycan-binding protein, CsiV MADE_1012165 06e57339e10da5fd813afa83e71cd7ba 524 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 524 349.624 T 13-10-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 MADE_1012165 06e57339e10da5fd813afa83e71cd7ba 524 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 510 1.1E-259 T 13-10-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 MADE_1012165 06e57339e10da5fd813afa83e71cd7ba 524 TIGRFAM TIGR00774 NhaB: Na+/H+ antiporter NhaB 1 510 4.7E-251 T 13-10-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 MADE_1019875 ccf6db0064f1c94b244028af1d862955 254 Pfam PF01203 Type II secretion system (T2SS), protein N 37 249 1.0E-47 T 13-10-2018 IPR022792 Type II secretion system, protein N MADE_1001485 14b455f629a743248848ef5a5d1e8b7a 232 Pfam PF13795 HupE / UreJ protein 49 199 2.3E-50 T 13-10-2018 IPR032809 Putative HupE/UreJ protein MADE_1009065 ca33622e08ecaa481c48af4f1766a82f 308 Pfam PF04784 Protein of unknown function, DUF547 111 228 5.2E-26 T 13-10-2018 IPR006869 Domain of unknown function DUF547 MADE_1020430 c741e732171a403b47a29273be35cd83 194 Pfam PF03942 DTW domain 3 171 2.8E-40 T 13-10-2018 IPR005636 DTW MADE_1020430 c741e732171a403b47a29273be35cd83 194 SMART SM01144 1 188 1.7E-52 T 13-10-2018 IPR005636 DTW MADE_1001520 5887ff839a8aed31268b7b7c77301c2d 163 Pfam PF04214 Protein of unknown function, DUF 62 129 6.4E-26 T 13-10-2018 IPR007332 Protein of unknown function DUF411 MADE_1010035 9d874906e9b811d8f68006dedfa9afd8 343 Gene3D G3DSA:1.20.120.350 36 153 4.1E-6 T 13-10-2018 IPR027359 Voltage-dependent channel domain superfamily MADE_1009810 f848fcf652ddd2840cb8bf35585b8988 184 Pfam PF11993 Ribosomal S4P (gammaproteobacterial) 36 166 2.0E-6 T 13-10-2018 IPR021879 Ribosomal S4P (gammaproteobacterial) MADE_1012705 40e0a9effb9902573bf78b62c684ec29 77 SUPERFAMILY SSF46785 4 39 5.62E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily MADE_1012705 40e0a9effb9902573bf78b62c684ec29 77 Gene3D G3DSA:1.10.10.10 1 42 2.4E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily MADE_1010455 7a9a4c458a3a4d425342d366f0d223c1 219 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 8 211 1.4E-53 T 13-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain MADE_1013700 9143cd23a5dca1ac8dc782441c6a9473 260 Pfam PF05742 Transport and Golgi organisation 2 1 245 2.2E-70 T 13-10-2018 IPR008551 Transport and Golgi organisation protein 2 MADE_1010000 df12a55283b0ef46f36f0cb3c455b5fc 204 Pfam PF07290 Protein of unknown function (DUF1449) 10 203 1.4E-58 T 13-10-2018 IPR010840 Protein of unknown function DUF1449 MADE_1007015 3399776b1cbe24cf1e8f0358c140f3d2 431 Pfam PF02447 GntP family permease 5 244 2.4E-11 T 13-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 MADE_1012265 88a1b192732b990d95914dd646b92781 302 Pfam PF01925 Sulfite exporter TauE/SafE 43 296 1.3E-36 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 MADE_1008530 f95c9e12d3b223a8a17c43a545855ab1 448 Pfam PF03553 Na+/H+ antiporter family 246 432 2.4E-10 T 13-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MADE_1008530 f95c9e12d3b223a8a17c43a545855ab1 448 Pfam PF03553 Na+/H+ antiporter family 17 221 2.1E-14 T 13-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 MADE_1016395 6e4eff17292859812b5c99d206592a2b 151 Pfam PF10614 Type VIII secretion system (T8SS), CsgF protein 10 148 1.2E-24 T 13-10-2018 IPR018893 Type VIII secretion system, CsgF MADE_1006790 6eb5bba8c070c5eeae223d3faa2ad72f 324 Pfam PF01882 Protein of unknown function DUF58 57 141 2.7E-21 T 13-10-2018 IPR002881 Domain of unknown function DUF58 MADE_1009680 c8ccc4389e7fca4f69382df16f421258 368 Pfam PF04245 37-kD nucleoid-associated bacterial protein 9 358 4.9E-92 T 13-10-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 MADE_1008325 c8df7d9c1ba81e0473edcdc1ad4d9b2f 199 Pfam PF07238 PilZ domain 93 179 1.3E-8 T 13-10-2018 IPR009875 PilZ domain GO:0035438 MADE_1009090 45177f2578dee517bdc8597945625f56 283 Pfam PF04116 Fatty acid hydroxylase superfamily 109 243 1.7E-27 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 MADE_1016030 7780888202686efb572f85987f2a7f2a 73 SUPERFAMILY SSF47598 4 48 5.23E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 MADE_1016030 7780888202686efb572f85987f2a7f2a 73 Gene3D G3DSA:1.10.1220.10 1 49 7.0E-6 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 MADE_1000525 7242f84b69ac0469cb5a945015942129 82 Pfam PF11173 Protein of unknown function (DUF2960) 1 79 7.1E-36 T 13-10-2018 IPR021343 Protein of unknown function DUF2960 MADE_000001023520 70e365ec185bbcb90baf1fa78234cdaf 135 Pfam PF13430 Domain of unknown function (DUF4112) 11 110 9.6E-33 T 13-10-2018 IPR025187 Protein of unknown function DUF4112 MADE_1013905 97cf6dc4058988748a5b14a9e7e56fa4 321 SUPERFAMILY SSF52540 6 125 1.31E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase MADE_1006945 8f228f8c8648f80c7ddd03126660e898 428 Pfam PF04286 Protein of unknown function (DUF445) 53 425 2.0E-87 T 13-10-2018 IPR007383 Protein of unknown function DUF445 MADE_000001023140 bbf54aeca2607b2fb82a6c6a59d1e9d2 387 SUPERFAMILY SSF56935 26 387 6.23E-33 T 13-10-2018 MADE_1006845 28c8fa8f6f30789bee1f356d205d75e8 347 Pfam PF01594 AI-2E family transporter 13 325 1.7E-61 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like MADE_1020165 6e7eedf6b61315794500b2396646bf89 1302 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 903 1244 4.7E-49 T 13-10-2018 IPR007452 Translocation and assembly module TamB MADE_1008720 9779ad9dcf36a9f67004316026120191 339 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 8 339 32.345 T 13-10-2018 IPR003770 Endolytic murein transglycosylase MADE_1008720 9779ad9dcf36a9f67004316026120191 339 Gene3D G3DSA:3.30.160.60 309 339 7.3E-12 T 13-10-2018 MADE_1008720 9779ad9dcf36a9f67004316026120191 339 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 1 335 3.9E-86 T 13-10-2018 IPR003770 Endolytic murein transglycosylase MADE_1008720 9779ad9dcf36a9f67004316026120191 339 Pfam PF02618 YceG-like family 42 334 1.5E-79 T 13-10-2018 IPR003770 Endolytic murein transglycosylase MADE_1008420 ef84b1a4cfd012d84b7f9c79baef0ae4 328 SUPERFAMILY SSF143422 16 192 1.08E-17 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 MADE_1000605 ee2bf4ce880fb8a37b62b08b33afee3c 229 SUPERFAMILY SSF55166 78 195 5.49E-10 T 13-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 MADE_1001755 7052893e253043235bfd8ff8c8eaaf3c 111 Pfam PF05717 IS66 Orf2 like protein 8 105 2.2E-32 T 13-10-2018 IPR008878 Transposase IS66, Orf2 MADE_1016765 f5256fc4489cba908ad87dcfcc7fccd0 222 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 219 3.3E-78 T 13-10-2018 IPR014319 Phage shock protein, PspA MADE_1016765 f5256fc4489cba908ad87dcfcc7fccd0 222 Pfam PF04012 PspA/IM30 family 2 220 5.8E-43 T 13-10-2018 IPR007157 PspA/IM30 MADE_1009885 7f294356692a1f8e1632637ce81382b2 429 Pfam PF02646 RmuC family 120 416 1.2E-106 T 13-10-2018 IPR003798 DNA recombination RmuC MADE_000001022185 a4074ac9fc10e41da38f90afd32e2096 118 Pfam PF04219 Protein of unknown function, DUF 13 99 9.1E-34 T 13-10-2018 IPR007335 Protein of unknown function DUF413 MADE_1016970 4ad88738aedea04ac17d581064a3ac1c 270 Pfam PF11101 Protein of unknown function (DUF2884) 32 260 2.3E-65 T 13-10-2018 IPR021307 Protein of unknown function DUF2884 MADE_1019610 fab19cbfd71a75098a93f8665ca8fdaa 122 SUPERFAMILY SSF56349 11 110 3.53E-9 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 MADE_1019610 fab19cbfd71a75098a93f8665ca8fdaa 122 Gene3D G3DSA:1.10.443.10 4 117 6.1E-7 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 MADE_1000300 810c54dcbeedd2ca5873ebaa1bb925b2 157 Gene3D G3DSA:3.40.190.10 39 156 2.4E-12 T 13-10-2018 MADE_1000300 810c54dcbeedd2ca5873ebaa1bb925b2 157 SUPERFAMILY SSF53850 33 146 1.19E-15 T 13-10-2018 MADE_000001021850 541e88c8ea559d402451e6297e583862 211 SUPERFAMILY SSF55961 34 136 6.53E-11 T 13-10-2018 MADE_000001021850 541e88c8ea559d402451e6297e583862 211 Gene3D G3DSA:3.30.530.20 37 184 8.2E-12 T 13-10-2018 IPR023393 START-like domain superfamily MADE_1009275 8ac5cf22646d364d05007bf16501d3ca 81 Pfam PF07362 Post-segregation antitoxin CcdA 11 81 5.0E-30 T 13-10-2018 IPR009956 Post-segregation antitoxin CcdA MADE_000001020855 9f6dcf92e770c6ba40562ba3ca5269d8 194 Gene3D G3DSA:1.20.1600.10 37 194 1.7E-25 T 13-10-2018 MADE_000001020855 9f6dcf92e770c6ba40562ba3ca5269d8 194 SUPERFAMILY SSF56954 6 192 1.14E-27 T 13-10-2018 MADE_000001020855 9f6dcf92e770c6ba40562ba3ca5269d8 194 Pfam PF02321 Outer membrane efflux protein 38 191 5.0E-15 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 MADE_1006785 bf416e76026d1d5975857c3050908f2a 222 Pfam PF14316 Domain of unknown function (DUF4381) 33 176 3.9E-36 T 13-10-2018 IPR025489 Protein of unknown function (DUF4381 MADE_1005610 c72a518254db006819c5b8dfa9f63578 150 Pfam PF07681 DoxX 15 100 2.2E-9 T 13-10-2018 IPR032808 DoxX family MADE_1007215 ccdf6c99718b0f434cd82358b6be514c 218 Pfam PF12973 ChrR Cupin-like domain 18 108 4.0E-41 T 13-10-2018 IPR025979 ChrR-like cupin domain MADE_1007215 ccdf6c99718b0f434cd82358b6be514c 218 Pfam PF12973 ChrR Cupin-like domain 126 211 1.3E-31 T 13-10-2018 IPR025979 ChrR-like cupin domain MADE_1007215 ccdf6c99718b0f434cd82358b6be514c 218 SUPERFAMILY SSF51182 117 216 1.42E-24 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_1007215 ccdf6c99718b0f434cd82358b6be514c 218 Gene3D G3DSA:2.60.120.10 1 215 5.1E-80 T 13-10-2018 IPR014710 RmlC-like jelly roll fold MADE_1007215 ccdf6c99718b0f434cd82358b6be514c 218 SUPERFAMILY SSF51182 2 128 1.15E-36 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily MADE_000001021670 887aafee047096f323ee071e752ce5eb 138 Pfam PF16108 Domain of unknown function (DUF4826) 12 137 4.5E-49 T 13-10-2018 IPR032251 Protein of unknown function DUF4826 MADE_1012400 83dd866325ba7424270178a2b41483e4 253 Pfam PF01618 MotA/TolQ/ExbB proton channel family 98 211 4.0E-23 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MADE_1012400 83dd866325ba7424270178a2b41483e4 253 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 182 199 - T 13-10-2018 IPR000540 Flagellar motor protein MotA, conserved site MADE_1014615 6c58effa1f41dbdcbc901105dbd002ff 97 Pfam PF11753 Protein of unknwon function (DUF3310) 23 82 1.3E-20 T 13-10-2018 IPR021739 SaV-like MADE_1019620 9c1cfbe3334cad638aab9363e1126dda 242 Pfam PF13590 Domain of unknown function (DUF4136) 35 205 5.3E-11 T 13-10-2018 IPR025411 Domain of unknown function DUF4136 MADE_1008675 9c85cdcb66b78de0897408af226ef29e 220 Pfam PF02620 Uncharacterized ACR, COG1399 105 216 7.1E-20 T 13-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD MADE_1008375 91f2a84588450b8564b3d1da3f337800 423 Pfam PF13692 Glycosyl transferases group 1 196 316 5.1E-14 T 13-10-2018 MADE_1008375 91f2a84588450b8564b3d1da3f337800 423 Gene3D G3DSA:3.40.50.2000 189 367 1.2E-7 T 13-10-2018 MADE_1008375 91f2a84588450b8564b3d1da3f337800 423 SUPERFAMILY SSF53756 8 303 1.88E-14 T 13-10-2018 MADE_1008055 d30284cafc47639a4195531929ebff3b 208 Pfam PF02517 CAAX protease self-immunity 103 191 7.3E-11 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 MADE_1016110 c7c5e981ad24a77ec90a611b597684ae 377 Pfam PF13795 HupE / UreJ protein 189 349 2.4E-42 T 13-10-2018 IPR032809 Putative HupE/UreJ protein MADE_000001020875 8af5cbdb5a6921edeb41fbd41db6034a 86 Pfam PF13700 Domain of unknown function (DUF4158) 9 85 3.2E-14 T 13-10-2018 IPR025296 Domain of unknown function DUF4158 MADE_1006755 fde356ef6eab0ffc3e9e6c9141b51188 234 Pfam PF11859 Protein of unknown function (DUF3379) 1 230 1.0E-79 T 13-10-2018 IPR021806 Protein of unknown function DUF3379 MADE_1018230 a5d5c98f2b77f75612825ec2c2758171 256 Pfam PF01618 MotA/TolQ/ExbB proton channel family 139 243 1.4E-16 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel MADE_1012700 2557b4b23daaa6160d2c365ee4306e5c 299 Pfam PF01758 Sodium Bile acid symporter family 12 195 2.3E-30 T 13-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 MADE_1012700 2557b4b23daaa6160d2c365ee4306e5c 299 Gene3D G3DSA:1.20.1530.20 2 289 1.4E-71 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily MADE_1015460 cbf4c41e96956ae187d4ee2aaefbfdbc 58 Pfam PF12065 Protein of unknown function (DUF3545) 2 56 2.4E-23 T 13-10-2018 IPR021932 Protein of unknown function DUF3545 MADE_1010680 0c5079b2a6f69aeeef752bcc5936fd3d 145 Pfam PF10116 Protein required for attachment to host cells 7 144 1.6E-24 T 13-10-2018 IPR019291 Host attachment protein MADE_000001022355 d2ab310f27df2f27901acf2d24278195 229 Pfam PF08889 WbqC-like protein family 7 220 2.1E-66 T 13-10-2018 IPR014985 WbqC-like protein family MADE_1000360 1ac926ed7c963a9223d9a6524c00f8db 83 Pfam PF04380 Membrane fusogenic activity 1 78 9.3E-30 T 13-10-2018 IPR007475 Membrane fusogenic activity MADE_1016220 f85136e8c36610b45f5a2e6a401836a3 139 SUPERFAMILY SSF49313 42 132 3.53E-5 T 13-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 MADE_1011550 deda15c34ae7429fd2e15e424eeba21d 74 SUPERFAMILY SSF47384 9 64 1.96E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 MADE_000001022425 200e65c2138bc017654ee3c8c2dd4888 171 Pfam PF06127 Protein of unknown function (DUF962) 1 152 2.6E-25 T 13-10-2018 IPR009305 Protein of unknown function DUF962 MADE_1005305 29aa1ebe54afbc9515ffbadce5db2419 214 Pfam PF07209 Protein of unknown function (DUF1415) 35 200 1.8E-53 T 13-10-2018 IPR009858 Protein of unknown function DUF1415 MADE_1001410 dfb6f71522d1ffddc3da6ef1328b1e56 339 Pfam PF04250 Protein of unknown function (DUF429) 60 245 2.2E-13 T 13-10-2018 IPR007362 Protein of unknown function DUF429 MADE_1009280 63fd8ef3322d4ade9f3b6a464e443aea 271 SUPERFAMILY SSF143422 3 140 2.22E-16 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 MADE_000001020775 e115ca04c9d5287cd71fc7e7a7ccabbc 393 SUPERFAMILY SSF56935 17 393 3.36E-28 T 13-10-2018 MADE_1004885 4ff745c17375db8cd1c99dd20d329ef7 124 Pfam PF11399 Protein of unknown function (DUF3192) 22 119 2.1E-41 T 13-10-2018 IPR021534 Protein of unknown function DUF3192 MADE_1001575 0df675fddb50af5fb7fa45cf098538d2 304 Pfam PF05425 Copper resistance protein D 197 296 4.3E-15 T 13-10-2018 IPR008457 Copper resistance protein D GO:0016021 MADE_1009725 9883962b006dd2f95a923151ee0b543d 280 PIRSF PIRSF028200 1 280 3.2E-64 T 13-10-2018 IPR016875 Uncharacterised conserved protein UCP028200 MADE_1005495 801bbb19b526583c2c6e65f6c6bb2d2a 267 Pfam PF01526 Tn3 transposase DDE domain 2 245 1.9E-76 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 MADE_1013840 bd92333f349c522b06cbfa330bce236a 227 SUPERFAMILY SSF53474 62 195 1.45E-6 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold MADE_1018150 49e17093751f387d6a58acee24780e2c 211 Pfam PF02036 SCP-2 sterol transfer family 15 120 4.6E-11 T 13-10-2018 IPR003033 SCP2 sterol-binding domain MADE_1004645 05b66264188c667f6960adaa47ef41ec 187 Pfam PF07603 Protein of unknown function (DUF1566) 61 182 2.0E-27 T 13-10-2018 IPR011460 Protein of unknown function DUF1566 MADE_1014200 47289232f8695888dd774108e6314bac 389 Gene3D G3DSA:1.20.1250.20 206 389 1.3E-13 T 13-10-2018 MADE_1014200 47289232f8695888dd774108e6314bac 389 Gene3D G3DSA:1.20.1250.20 11 199 1.6E-15 T 13-10-2018 MADE_1014200 47289232f8695888dd774108e6314bac 389 SUPERFAMILY SSF103473 13 386 1.7E-40 T 13-10-2018 IPR036259 MFS transporter superfamily MADE_1014200 47289232f8695888dd774108e6314bac 389 Pfam PF07690 Major Facilitator Superfamily 14 347 1.1E-26 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 MADE_1005920 b3c111fd35556d169274cca3a261e98d 148 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 3 141 3.3E-25 T 13-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 MADE_1005920 b3c111fd35556d169274cca3a261e98d 148 Pfam PF02050 Flagellar FliJ protein 19 140 4.9E-28 T 13-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 MADE_1013030 822e56b45f68a12193895893ae874692 929 Pfam PF02687 FtsX-like permease family 829 918 9.1E-10 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 MADE_1002585 6541a27c132c158653d219325125c9ae 193 Pfam PF05137 Fimbrial assembly protein (PilN) 101 176 3.7E-19 T 13-10-2018 IPR007813 Fimbrial assembly PilN MADE_1001965 51dc87dde70513fa10124e5d7bb62576 248 Pfam PF05275 Copper resistance protein B precursor (CopB) 36 248 9.3E-72 T 13-10-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 MADE_1017000 f7edb65eaee87088796189bddb6ab484 373 SUPERFAMILY SSF50956 68 318 2.35E-9 T 13-10-2018 MADE_1016100 17c1aa9c7d49bd4669ee902d1579b9cf 188 Gene3D G3DSA:2.60.40.10 54 142 2.5E-6 T 13-10-2018 IPR013783 Immunoglobulin-like fold MADE_1016100 17c1aa9c7d49bd4669ee902d1579b9cf 188 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 74 139 5.8E-4 T 13-10-2018 IPR010221 VCBS repeat MADE_1000050 e409b1051bd0b3631a373c3abe96ad7e 155 Pfam PF10675 Protein of unknown function (DUF2489) 14 142 2.4E-41 T 13-10-2018 IPR019617 Domain of unknown function DUF2489 MADE_1013400 26f111c9bcd58cf8ed27e6c4f652e082 109 Pfam PF12514 Protein of unknown function (DUF3718) 43 107 3.7E-5 T 13-10-2018 IPR022193 Protein of unknown function DUF3718 MADE_1003140 35779f84f5b078ed139640023f32a93d 237 Pfam PF13643 Domain of unknown function (DUF4145) 111 198 1.0E-14 T 13-10-2018 IPR025285 Domain of unknown function DUF4145 MADE_1008835 38b72b2eb37c4bf63eb56ac5d02c2e99 181 Pfam PF11454 Protein of unknown function (DUF3016) 28 170 2.5E-45 T 13-10-2018 IPR021557 Protein of unknown function DUF3016 MADE_000001021745 f3787204a9861f3a11cbea51b754c57d 149 Pfam PF04217 Protein of unknown function, DUF412 5 144 2.9E-56 T 13-10-2018 IPR007334 Uncharacterised protein family UPF0208 MADE_1007500 ea06b6be985b26a4669c55d27aa3c8e1 493 Pfam PF13440 Polysaccharide biosynthesis protein 33 321 3.5E-45 T 13-10-2018 MADE_1012940 34b82842fe77ebad087de643cde0e29a 405 Pfam PF01757 Acyltransferase family 19 358 6.1E-13 T 13-10-2018 IPR002656 Acyltransferase 3 GO:0016747 MADE_1013335 37d64eda3e5c8cd2654ddf012ba61c72 72 Pfam PF10981 Protein of unknown function (DUF2788) 17 67 1.4E-19 T 13-10-2018 IPR021249 Protein of unknown function DUF2788 MADE_1011975 31c2b0c5a563a4bc03c4bee33a3ad46f 246 PIRSF PIRSF028688 74 244 3.1E-35 T 13-10-2018 IPR014549 Flagellar protein FlgO MADE_1004265 b083b9f81e7f5846719e22bc9e4dde56 145 Pfam PF06295 Protein of unknown function (DUF1043) 7 134 1.8E-22 T 13-10-2018 IPR009386 Protein of unknown function DUF1043 MADE_1018910 c68ef4ea1f41d623faeeae3f4ebb36da 337 Pfam PF13349 Putative adhesin 57 269 1.5E-7 T 13-10-2018 IPR025164 Putative adhesin MADE_1018510 41e9dbe1aafa31672b71b6530dbad74e 391 Pfam PF03773 Predicted permease 11 328 7.2E-43 T 13-10-2018 IPR005524 Predicted permease DUF318 MADE_000001023530 853850857582c9c48422d6fb9e0b894b 525 Pfam PF03806 AbgT putative transporter family 15 523 1.1E-214 T 13-10-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 MADE_1012280 5dc5e2b14a2e3e71f8bf0f6007ededc0 190 Pfam PF04366 Las17-binding protein actin regulator 102 190 1.4E-9 T 13-10-2018 IPR007461 Ysc84 actin-binding domain MADE_1003485 b25290fb41d0523e963684073cde6ab5 294 Pfam PF12048 Protein of unknown function (DUF3530) 35 264 2.2E-14 T 13-10-2018 IPR022529 Protein of unknown function DUF3530 MADE_1001860 69f54c1e33b36d3215f25d51064cc1fa 238 Pfam PF09335 SNARE associated Golgi protein 63 178 7.8E-18 T 13-10-2018 IPR032816 SNARE associated Golgi protein MADE_1010865 baf21b5e277b7fa1ab780855e3d68a66 140 Pfam PF09842 Predicted membrane protein (DUF2069) 11 113 3.0E-32 T 13-10-2018 IPR018643 Protein of unknown function DUF2069, membrane MADE_1005565 c0ae5f3e5c1697352dbc9a3d5d76e2c2 156 Pfam PF01526 Tn3 transposase DDE domain 2 135 6.9E-44 T 13-10-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 MADE_1001020 60cbc230db02111af077278c08b751b2 76 Pfam PF13627 Prokaryotic lipoprotein-attachment site 19 40 2.4E-7 T 13-10-2018 IPR032831 Prokaryotic lipoprotein-attachment site MADE_1000680 1d50056d46d99070e96e439ef1b2f96a 382 Pfam PF05128 Domain of unknown function (DUF697) 255 381 1.1E-21 T 13-10-2018 IPR021147 Protein of unknown function DUF697 MADE_1010480 4df49e9fa485f02bae9ff5c1d0a67daa 215 Pfam PF11205 Protein of unknown function (DUF2987) 23 167 4.6E-43 T 13-10-2018 IPR021370 Protein of unknown function DUF2987 MADE_1016400 9d14ee2fa037053542274ca12ced156d 130 Pfam PF10627 Curli assembly protein CsgE 28 129 5.9E-25 T 13-10-2018 IPR018900 Curli assembly protein CsgE MADE_1000545 0d0b5f0c0036d2fd2218b772d729f200 150 Pfam PF14015 Protein of unknown function (DUF4231) 19 97 1.7E-6 T 13-10-2018 IPR025325 Protein of unknown function DUF4231