locus-tag	class	description
BM526_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM526_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BM526_00020	COG0187	DNA topoisomerase II activity
BM526_00050	COG2818	Glycosylase
BM526_00060	COG3078	GTPase activator activity
BM526_00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM526_00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM526_00085	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BM526_00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BM526_00095	COG0569	domain protein
BM526_00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BM526_00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BM526_00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BM526_00120	COG0758	DNA mediated transformation
BM526_00135	COG0009	L-threonylcarbamoyladenylate synthase
BM526_00140	COG0408	coproporphyrinogen oxidase activity
BM526_00145	COG3047	cAMP biosynthetic process
BM526_00160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BM526_00230	COG2234	aminopeptidase activity
BM526_00235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM526_00235	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BM526_00250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BM526_00275	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM526_00305	COG3642	lipopolysaccharide core region biosynthetic process
BM526_00310	COG0859	PFAM glycosyl transferase family 9
BM526_00340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_00355	COG3161	chorismate lyase activity
BM526_00360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BM526_00380	COG0210	DNA helicase
BM526_00425	COG1959	2 iron, 2 sulfur cluster binding
BM526_00430	COG0730	response to heat
BM526_00460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM526_00465	COG4988	ABC transporter
BM526_00475	COG1271	oxidase subunit
BM526_00480	COG0425	Belongs to the sulfur carrier protein TusA family
BM526_00480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_00490	COG0450	alkyl hydroperoxide reductase
BM526_00495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM526_00500	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_00520	COG1024	Enoyl-CoA hydratase
BM526_00525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM526_00535	COG1960	acyl-CoA dehydrogenase activity
BM526_00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_00590	COG1129	ABC transporter
BM526_00590	COG0842	Transport permease protein
BM526_00595	COG0842	Transport permease protein
BM526_00605	COG4771	TonB-dependent receptor
BM526_00620	COG0583	DNA-binding transcription factor activity
BM526_00630	COG3106	COG3106 Predicted ATPase
BM526_00645	COG2184	nucleotidyltransferase activity
BM526_00650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BM526_00665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BM526_00670	COG0352	thiamine-phosphate diphosphorylase activity
BM526_00680	COG3071	HemY protein
BM526_00685	COG2959	enzyme of heme biosynthesis
BM526_00695	COG0181	hydroxymethylbilane synthase activity
BM526_00710	COG0194	GDP metabolic process
BM526_00720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM526_00730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM526_00735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BM526_00745	COG0678	peroxiredoxin activity
BM526_00760	COG1178	ABC-type Fe3 transport system permease component
BM526_00765	COG3842	ATPase activity
BM526_00770	COG0668	transmembrane transport
BM526_00775	COG2081	HI0933 family
BM526_00785	COG2200	EAL domain
BM526_00790	COG0583	DNA-binding transcription factor activity
BM526_00800	COG2076	Multidrug Resistance protein
BM526_00815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_00830	COG0427	acetyl-CoA hydrolase
BM526_00835	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM526_00850	COG0840	transmembrane signaling receptor activity
BM526_00860	COG3064	Membrane
BM526_00870	COG5001	Diguanylate cyclase
BM526_00870	COG5002	protein histidine kinase activity
BM526_00885	COG0514	ATP-dependent DNA helicase (RecQ)
BM526_00890	COG2239	Acts as a magnesium transporter
BM526_00895	COG2962	Rard protein
BM526_00900	COG3706	GGDEF domain
BM526_00900	COG0745	RESPONSE REGULATOR receiver
BM526_00905	COG0210	DNA helicase
BM526_00915	COG1011	Hydrolase
BM526_00930	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BM526_00935	COG0019	diaminopimelate decarboxylase activity
BM526_00965	COG0163	prenyltransferase activity
BM526_00970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM526_00980	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BM526_01005	COG1077	Cell shape determining protein MreB Mrl
BM526_01020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BM526_01025	COG2814	Major facilitator Superfamily
BM526_01030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_01060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BM526_01075	COG0629	single-stranded DNA binding
BM526_01105	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_01130	COG1349	DNA-binding transcription factor activity
BM526_01200	COG3409	Peptidoglycan-binding domain 1 protein
BM526_01200	COG3267	Type II secretory pathway component ExeA
BM526_01210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_01215	COG1459	type II secretion system
BM526_01260	COG1077	Cell shape determining protein MreB Mrl
BM526_01265	COG1792	Involved in formation and maintenance of cell shape
BM526_01270	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BM526_01280	COG1530	ribonuclease E activity
BM526_01290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM526_01295	COG0312	modulator of DNA gyrase
BM526_01300	COG3028	Belongs to the UPF0307 family
BM526_01305	COG0312	modulator of DNA gyrase
BM526_01320	COG0745	RESPONSE REGULATOR receiver
BM526_01325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_01325	COG4191	Histidine kinase
BM526_01330	COG0297	glycogen (starch) synthase activity
BM526_01340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BM526_01345	COG0596	Alpha beta hydrolase
BM526_01390	COG0745	RESPONSE REGULATOR receiver
BM526_01400	COG0835	chemotaxis
BM526_01415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM526_01430	COG0745	RESPONSE REGULATOR receiver
BM526_01435	COG0643	Histidine kinase
BM526_01435	COG2198	Histidine kinase
BM526_01440	COG0835	chemotaxis
BM526_01460	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM526_01510	COG0546	phosphoglycolate phosphatase activity
BM526_01535	COG0673	inositol 2-dehydrogenase activity
BM526_01545	COG2211	Major facilitator Superfamily
BM526_01550	COG1082	Xylose isomerase domain protein TIM barrel
BM526_01570	COG1454	alcohol dehydrogenase
BM526_01600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_01620	COG0089	rRNA binding
BM526_01630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BM526_01640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BM526_01655	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BM526_01660	COG0438	transferase activity, transferring glycosyl groups
BM526_01670	COG1519	Transferase
BM526_01690	COG0840	transmembrane signaling receptor activity
BM526_01705	COG0788	formyltetrahydrofolate deformylase activity
BM526_01715	COG1643	Atp-dependent helicase
BM526_01725	COG2951	lytic endotransglycosylase activity
BM526_01730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BM526_01740	COG2354	Protein conserved in bacteria
BM526_01750	COG4977	sequence-specific DNA binding
BM526_01765	COG0004	ammonium transporteR
BM526_01770	COG0405	Gamma-glutamyltransferase
BM526_01775	COG2837	iron assimilation
BM526_01790	COG0540	Belongs to the ATCase OTCase family
BM526_01815	COG0784	Response regulator, receiver
BM526_01815	COG2205	protein histidine kinase activity
BM526_01815	COG5002	protein histidine kinase activity
BM526_01830	COG3300	MHYT domain
BM526_01830	COG5001	Diguanylate cyclase
BM526_01840	COG1012	belongs to the aldehyde dehydrogenase family
BM526_01850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BM526_01865	COG0180	Tryptophanyl-tRNA synthetase
BM526_01870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BM526_01890	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BM526_01900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BM526_01935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BM526_01940	COG0281	malic enzyme
BM526_01950	COG0625	glutathione transferase activity
BM526_01960	COG0753	catalase activity
BM526_01985	COG5001	Diguanylate cyclase
BM526_01985	COG3300	MHYT domain
BM526_01990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BM526_01990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BM526_02000	COG0137	argininosuccinate synthase activity
BM526_02020	COG1803	Methylglyoxal synthase
BM526_02030	COG0745	RESPONSE REGULATOR receiver
BM526_02035	COG2205	protein histidine kinase activity
BM526_02040	COG2267	carboxylic ester hydrolase activity
BM526_02045	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BM526_02055	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BM526_02065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM526_02070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_02075	COG4942	peptidase
BM526_02080	COG2861	carbohydrate metabolic process
BM526_02105	COG1162	GTPase activity
BM526_02110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BM526_02130	COG0457	Tetratricopeptide repeat
BM526_02145	COG0028	Belongs to the TPP enzyme family
BM526_02165	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BM526_02170	COG0805	protein transport
BM526_02180	COG0084	hydrolase, TatD family'
BM526_02185	COG2203	Gaf domain
BM526_02185	COG5001	Diguanylate cyclase
BM526_02185	COG4251	negative regulation of phosphorylation
BM526_02185	COG3706	GGDEF domain
BM526_02195	COG0248	Ppx GppA phosphatase
BM526_02200	COG0513	Belongs to the DEAD box helicase family
BM526_02205	COG3118	belongs to the thioredoxin family
BM526_02210	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BM526_02220	COG5002	protein histidine kinase activity
BM526_02220	COG0784	Response regulator, receiver
BM526_02225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BM526_02235	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BM526_02250	COG0783	Belongs to the Dps family
BM526_02255	COG2133	pyrroloquinoline quinone binding
BM526_02260	COG4946	Tricorn protease homolog
BM526_02260	COG1506	peptidase
BM526_02260	COG0823	Involved in the tonB-independent uptake of proteins
BM526_02270	COG3118	belongs to the thioredoxin family
BM526_02285	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BM526_02295	COG1012	belongs to the aldehyde dehydrogenase family
BM526_02315	COG1757	Na H antiporter
BM526_02330	COG3876	Protein conserved in bacteria
BM526_02335	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BM526_02345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BM526_02355	COG0346	lactoylglutathione lyase activity
BM526_02380	COG2824	Alkylphosphonate utilization operon protein PhnA
BM526_02385	COG0454	-acetyltransferase
BM526_02595	COG0183	Belongs to the thiolase family
BM526_02600	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM526_02600	COG1024	Enoyl-CoA hydratase
BM526_02610	COG0006	proline dipeptidase activity
BM526_02620	COG0142	geranyltranstransferase activity
BM526_02650	COG4942	peptidase
BM526_02650	COG1388	LysM domain
BM526_02655	COG1238	metal cluster binding
BM526_02665	COG0585	pseudouridine synthase activity
BM526_02670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BM526_02680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BM526_02690	COG0840	transmembrane signaling receptor activity
BM526_02725	COG0494	nUDIX hydrolase
BM526_02730	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BM526_02735	COG0730	response to heat
BM526_02740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BM526_02745	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BM526_02750	COG2201	protein-glutamate methylesterase activity
BM526_02755	COG0745	RESPONSE REGULATOR receiver
BM526_02755	COG3706	GGDEF domain
BM526_02780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BM526_02795	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BM526_02805	COG1648	precorrin-2 dehydrogenase activity
BM526_02805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM526_02810	COG0513	Belongs to the DEAD box helicase family
BM526_02825	COG1538	Outer membrane efflux protein
BM526_02830	COG0494	nUDIX hydrolase
BM526_02840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BM526_02845	COG3150	esterase
BM526_02850	COG0187	DNA topoisomerase II activity
BM526_02860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_02885	COG1509	lysine 2,3-aminomutase activity
BM526_02895	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BM526_02910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BM526_02915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM526_02930	COG0271	Belongs to the BolA IbaG family
BM526_02945	COG3707	response regulator
BM526_02960	COG0659	secondary active sulfate transmembrane transporter activity
BM526_02965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BM526_02975	COG0243	molybdopterin cofactor binding
BM526_02980	COG1648	precorrin-2 dehydrogenase activity
BM526_02980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM526_02985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM526_02995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BM526_02995	COG1116	anion transmembrane transporter activity
BM526_03005	COG1116	anion transmembrane transporter activity
BM526_03020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM526_03025	COG4206	TonB-dependent receptor
BM526_03030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BM526_03035	COG0348	domain, Protein
BM526_03050	COG1960	acyl-CoA dehydrogenase activity
BM526_03055	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_03065	COG4948	Mandelate Racemase Muconate Lactonizing
BM526_03080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_03085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_03105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BM526_03110	COG0358	DNA primase activity
BM526_03115	COG1610	YqeY-like protein
BM526_03135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BM526_03140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM526_03155	COG0537	adenosine 5'-monophosphoramidase activity
BM526_03170	COG3135	benzoate transporter
BM526_03175	COG1396	sequence-specific DNA binding
BM526_03180	COG2974	May be involved in recombination
BM526_03185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_03185	COG4191	Histidine kinase
BM526_03190	COG0745	RESPONSE REGULATOR receiver
BM526_03195	COG5002	protein histidine kinase activity
BM526_03220	COG0811	peptide transport
BM526_03225	COG0811	peptide transport
BM526_03230	COG0848	biopolymer transport protein
BM526_03235	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BM526_03245	COG3437	response regulator, receiver
BM526_03250	COG5002	protein histidine kinase activity
BM526_03250	COG0784	Response regulator, receiver
BM526_03250	COG2205	protein histidine kinase activity
BM526_03255	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_03265	COG2133	pyrroloquinoline quinone binding
BM526_03275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM526_03305	COG0527	aspartate kinase activity
BM526_03315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BM526_03320	COG2967	ApaG domain
BM526_03330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BM526_03335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM526_03340	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BM526_03345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BM526_03355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM526_03375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BM526_03390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM526_03395	COG3956	TIGRFAM MazG family protein
BM526_03420	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BM526_03425	COG0723	plastoquinol--plastocyanin reductase activity
BM526_03430	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BM526_03435	COG2857	Cytochrome c1
BM526_03440	COG0625	glutathione transferase activity
BM526_03445	COG2969	positive regulation of protein catabolic process
BM526_03460	COG0745	RESPONSE REGULATOR receiver
BM526_03465	COG2239	Acts as a magnesium transporter
BM526_03470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM526_03480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM526_03490	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BM526_03495	COG1137	ATPase activity
BM526_03500	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BM526_03510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BM526_03525	COG1127	ABC transporter
BM526_03530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BM526_03535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM526_03540	COG2854	intermembrane phospholipid transfer
BM526_03550	COG5007	Belongs to the BolA IbaG family
BM526_03560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM526_03565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM526_03575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BM526_03610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM526_03625	COG4771	TonB-dependent receptor
BM526_03630	COG0697	spore germination
BM526_03640	COG0784	Response regulator, receiver
BM526_03640	COG2205	protein histidine kinase activity
BM526_03665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BM526_03675	COG0126	phosphoglycerate kinase activity
BM526_03680	COG3588	fructose-bisphosphate aldolase
BM526_03690	COG1506	peptidase
BM526_03690	COG4946	Tricorn protease homolog
BM526_03690	COG0823	Involved in the tonB-independent uptake of proteins
BM526_03695	COG0248	Ppx GppA phosphatase
BM526_03700	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BM526_03710	COG0573	inorganic phosphate transmembrane transporter activity
BM526_03720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BM526_03730	COG0306	phosphate transporter
BM526_03740	COG0583	DNA-binding transcription factor activity
BM526_03750	COG1272	protein, Hemolysin III
BM526_03755	COG1846	Transcriptional regulator
BM526_03760	COG1764	response to oxidative stress
BM526_03775	COG1739	Uncharacterized protein family UPF0029
BM526_03795	COG0583	DNA-binding transcription factor activity
BM526_03800	COG4989	oxidoreductase activity
BM526_03815	COG0420	3'-5' exonuclease activity
BM526_03820	COG0419	ATPase involved in DNA repair
BM526_03830	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BM526_03845	COG2188	Transcriptional regulator
BM526_03855	COG2986	histidine ammonia-lyase
BM526_03880	COG0488	(ABC) transporter
BM526_03905	COG0668	transmembrane transport
BM526_03950	COG1346	cytolysis
BM526_03980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM526_03990	COG0513	Belongs to the DEAD box helicase family
BM526_04000	COG3267	Type II secretory pathway component ExeA
BM526_04000	COG3409	Peptidoglycan-binding domain 1 protein
BM526_04015	COG0066	3-isopropylmalate dehydratase activity
BM526_04025	COG0473	3-isopropylmalate dehydrogenase activity
BM526_04030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BM526_04055	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BM526_04070	COG4555	ABC transporter
BM526_04075	COG1668	transmembrane transport
BM526_04095	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM526_04100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM526_04105	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM526_04115	COG1138	Cytochrome C-type biogenesis protein
BM526_04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BM526_04135	COG2853	Lipoprotein
BM526_04140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM526_04150	COG3104	oligopeptide transport
BM526_04160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BM526_04165	COG1555	photosystem II stabilization
BM526_04165	COG1596	polysaccharide export
BM526_04170	COG0473	3-isopropylmalate dehydrogenase activity
BM526_04185	COG1611	Belongs to the LOG family
BM526_04190	COG3706	GGDEF domain
BM526_04190	COG0745	RESPONSE REGULATOR receiver
BM526_04195	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BM526_04195	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BM526_04250	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BM526_04255	COG0024	Methionine aminopeptidase
BM526_04260	COG0052	Belongs to the universal ribosomal protein uS2 family
BM526_04270	COG0528	UMP kinase activity
BM526_04280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BM526_04285	COG0575	Belongs to the CDS family
BM526_04310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM526_04330	COG0587	DNA-directed DNA polymerase activity
BM526_04335	COG0825	malonyl-CoA metabolic process
BM526_04340	COG0037	tRNA processing
BM526_04360	COG0590	tRNA wobble adenosine to inosine editing
BM526_04375	COG2840	Smr protein MutS2
BM526_04405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_04410	COG2197	response regulator
BM526_04450	COG0835	chemotaxis
BM526_04450	COG0784	Response regulator, receiver
BM526_04455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BM526_04460	COG1815	bacterial-type flagellum-dependent cell motility
BM526_04465	COG1558	bacterial-type flagellum-dependent cell motility
BM526_04470	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BM526_04475	COG1749	Flagellar hook protein flgE
BM526_04480	COG4787	bacterial-type flagellum-dependent cell motility
BM526_04485	COG4786	Flagellar basal body rod
BM526_04500	COG1705	Flagellar rod assembly protein muramidase FlgJ
BM526_04500	COG3951	Flagellar rod assembly protein muramidase FlgJ
BM526_04505	COG1256	bacterial-type flagellum assembly
BM526_04530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM526_04535	COG1334	flagellar protein FlaG
BM526_04540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BM526_04565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM526_04575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BM526_04580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM526_04590	COG1215	transferase activity, transferring glycosyl groups
BM526_04595	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM526_04600	COG1086	Polysaccharide biosynthesis protein
BM526_04615	COG3475	LICD family
BM526_04620	COG2089	acid synthase
BM526_04630	COG1083	cytidylyl-transferase
BM526_04640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM526_04650	COG2204	response regulator
BM526_04655	COG3852	Histidine kinase
BM526_04660	COG2204	response regulator
BM526_04665	COG1677	Flagellar hook-basal body complex protein FliE
BM526_04670	COG1766	The M ring may be actively involved in energy transduction
BM526_04675	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BM526_04725	COG1987	bacterial-type flagellum assembly
BM526_04740	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM526_04750	COG0455	bacterial-type flagellum organization
BM526_04765	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BM526_04770	COG0643	Histidine kinase
BM526_04770	COG2198	Histidine kinase
BM526_04780	COG1192	Involved in chromosome partitioning
BM526_04790	COG0835	chemotaxis
BM526_04805	COG0646	methionine synthase
BM526_04805	COG1410	methionine synthase
BM526_04810	COG0646	methionine synthase
BM526_04810	COG1410	methionine synthase
BM526_04820	COG3123	guanosine phosphorylase activity
BM526_04830	COG0583	DNA-binding transcription factor activity
BM526_04835	COG0583	DNA-binding transcription factor activity
BM526_04845	COG0659	secondary active sulfate transmembrane transporter activity
BM526_04860	COG3590	peptidase
BM526_04870	COG2137	regulation of response to DNA damage stimulus
BM526_04875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BM526_04905	COG5016	pyruvate
BM526_04905	COG0511	ligase activity, forming carbon-carbon bonds
BM526_04910	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BM526_04915	COG4172	Belongs to the ABC transporter superfamily
BM526_04925	COG4171	peptide transport system, permease
BM526_04930	COG4168	peptide transport system, permease
BM526_04935	COG0747	negative chemotaxis
BM526_04940	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BM526_04945	COG1842	Phage shock protein A
BM526_04975	COG0625	glutathione transferase activity
BM526_04980	COG1522	sequence-specific DNA binding
BM526_05045	COG0811	peptide transport
BM526_05050	COG0811	peptide transport
BM526_05055	COG0848	biopolymer transport protein
BM526_05070	COG1444	tRNA N-acetyltransferase activity
BM526_05110	COG0456	acetyltransferase
BM526_05125	COG0583	DNA-binding transcription factor activity
BM526_05130	COG2814	Major facilitator Superfamily
BM526_05135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM526_05140	COG0656	L-ascorbic acid biosynthetic process
BM526_05150	COG3706	GGDEF domain
BM526_05185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM526_05215	COG0543	2 iron, 2 sulfur cluster binding
BM526_05215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BM526_05230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BM526_05235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM526_05240	COG0564	pseudouridine synthase activity
BM526_05250	COG0612	Peptidase, M16
BM526_05255	COG2918	glutathione biosynthetic process
BM526_05275	COG2840	Smr protein MutS2
BM526_05280	COG2890	protein-(glutamine-N5) methyltransferase activity
BM526_05295	COG2719	SpoVR family
BM526_05300	COG2718	Belongs to the UPF0229 family
BM526_05305	COG2766	serine protein kinase
BM526_05315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BM526_05320	COG4771	TonB-dependent receptor
BM526_05345	COG0450	alkyl hydroperoxide reductase
BM526_05350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM526_05355	COG2885	chlorophyll binding
BM526_05360	COG0584	glycerophosphoryl diester phosphodiesterase
BM526_05365	COG0346	lactoylglutathione lyase activity
BM526_05370	COG1278	Cold shock
BM526_05385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BM526_05390	COG4660	Part of a membrane complex involved in electron transport
BM526_05395	COG4659	FMN binding
BM526_05400	COG4658	electron transport chain
BM526_05405	COG4656	Part of a membrane complex involved in electron transport
BM526_05410	COG2878	Part of a membrane complex involved in electron transport
BM526_05430	COG0534	Mate efflux family protein
BM526_05435	COG0556	nucleotide-excision repair
BM526_05450	COG0602	queuosine metabolic process
BM526_05460	COG0367	asparagine synthase
BM526_05485	COG0471	metal ion transport
BM526_05485	COG3273	potassium ion transport
BM526_05500	COG0529	Catalyzes the synthesis of activated sulfate
BM526_05505	COG0175	sulfate reduction
BM526_05510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_05515	COG3706	GGDEF domain
BM526_05540	COG2304	oxidoreductase activity
BM526_05560	COG0714	Associated with various cellular activities
BM526_05570	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM526_05570	COG1024	Enoyl-CoA hydratase
BM526_05585	COG1025	Belongs to the peptidase M16 family
BM526_05590	COG2062	phosphohistidine phosphatase, SixA
BM526_05600	COG4536	flavin adenine dinucleotide binding
BM526_05605	COG4137	Cytochrome C assembly protein
BM526_05610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BM526_05655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_05660	COG1132	(ABC) transporter
BM526_05675	COG0228	four-way junction DNA binding
BM526_05680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BM526_05685	COG0336	Belongs to the RNA methyltransferase TrmD family
BM526_05690	COG0335	large ribosomal subunit rRNA binding
BM526_05695	COG2860	membrane
BM526_05705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BM526_05710	COG1605	Chorismate mutase
BM526_05710	COG0287	Prephenate dehydrogenase
BM526_05715	COG0077	Prephenate dehydratase
BM526_05715	COG1605	Chorismate mutase
BM526_05725	COG0023	Translation Initiation Factor
BM526_05755	COG2205	protein histidine kinase activity
BM526_05765	COG2204	response regulator
BM526_05770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM526_05785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BM526_05790	COG0494	nUDIX hydrolase
BM526_05795	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BM526_05805	COG2255	four-way junction helicase activity
BM526_05810	COG0824	Thioesterase
BM526_05815	COG0811	peptide transport
BM526_05830	COG0823	Involved in the tonB-independent uptake of proteins
BM526_05835	COG2885	chlorophyll binding
BM526_05840	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BM526_05860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BM526_05875	COG4667	esterase of the alpha-beta hydrolase superfamily
BM526_05880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM526_05890	COG0784	Response regulator, receiver
BM526_05890	COG2205	protein histidine kinase activity
BM526_05905	COG0300	oxidoreductase activity
BM526_05910	COG3038	cytochrome b561
BM526_05940	COG0583	DNA-binding transcription factor activity
BM526_05945	COG1064	alcohol dehydrogenase
BM526_05950	COG1451	nucleotide metabolic process
BM526_05955	COG0517	IMP dehydrogenase activity
BM526_05960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_05970	COG1309	transcriptional regulator
BM526_05975	COG4774	siderophore transport
BM526_05995	COG3706	GGDEF domain
BM526_06005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM526_06005	COG3008	intermembrane lipid transfer
BM526_06010	COG2995	paraquat-inducible protein a
BM526_06030	COG2207	Transcriptional regulator
BM526_06035	COG0017	Asparaginyl-tRNA synthetase
BM526_06050	COG0189	ligase activity
BM526_06080	COG0156	8-amino-7-oxononanoate synthase activity
BM526_06085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM526_06095	COG3340	Belongs to the peptidase S51 family
BM526_06100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BM526_06105	COG4139	cobalamin transport
BM526_06110	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BM526_06115	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BM526_06130	COG5265	(ABC) transporter
BM526_06135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BM526_06145	COG0745	RESPONSE REGULATOR receiver
BM526_06165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM526_06205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM526_06220	COG2755	lipolytic protein G-D-S-L family
BM526_06225	COG4181	ATPase activity
BM526_06230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BM526_06235	COG1090	epimerase
BM526_06240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM526_06245	COG0628	permease
BM526_06255	COG0745	RESPONSE REGULATOR receiver
BM526_06270	COG2350	Protein conserved in bacteria
BM526_06275	COG0159	tryptophan synthase activity
BM526_06285	COG0134	indole-3-glycerol-phosphate synthase activity
BM526_06285	COG0135	phosphoribosylanthranilate isomerase activity
BM526_06290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM526_06300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BM526_06305	COG0613	PHP domain protein
BM526_06310	COG0009	L-threonylcarbamoyladenylate synthase
BM526_06315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BM526_06320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BM526_06330	COG0656	L-ascorbic acid biosynthetic process
BM526_06335	COG0110	maltose O-acetyltransferase activity
BM526_06345	COG2733	membrane
BM526_06365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_06370	COG0500	methyltransferase
BM526_06375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM526_06380	COG0497	DNA recombination
BM526_06385	COG0783	Belongs to the Dps family
BM526_06395	COG1454	alcohol dehydrogenase
BM526_06400	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_06410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BM526_06415	COG2610	gluconate transmembrane transporter activity
BM526_06435	COG2205	protein histidine kinase activity
BM526_06435	COG0784	Response regulator, receiver
BM526_06435	COG2198	Histidine kinase
BM526_06455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BM526_06465	COG0484	heat shock protein binding
BM526_06470	COG3909	cytochrome
BM526_06490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BM526_06495	COG0505	Belongs to the CarA family
BM526_06500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BM526_06505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM526_06525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BM526_06530	COG0280	phosphate acetyltransferase
BM526_06530	COG0857	belongs to the CobB CobQ family
BM526_06535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BM526_06540	COG4535	Mg2 and Co2 transporter CorC
BM526_06550	COG1702	phosphate starvation-inducible protein PhoH
BM526_06560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM526_06590	COG1607	acyl-coa hydrolase
BM526_06595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM526_06605	COG1115	amino acid carrier protein
BM526_06650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM526_06655	COG0012	GTP binding
BM526_06670	COG1064	alcohol dehydrogenase
BM526_06685	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BM526_06695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BM526_06700	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BM526_06705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BM526_06715	COG2890	protein-(glutamine-N5) methyltransferase activity
BM526_06720	COG3437	response regulator, receiver
BM526_06720	COG0784	Response regulator, receiver
BM526_06725	COG3094	Invasion gene expression up-regulator, SirB
BM526_06740	COG0583	DNA-binding transcription factor activity
BM526_06750	COG2363	Small membrane protein
BM526_06765	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BM526_06770	COG0515	serine threonine protein kinase
BM526_06775	COG2116	formate transmembrane transporter activity
BM526_06790	COG0714	Associated with various cellular activities
BM526_06795	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BM526_06800	COG0033	Phosphoglucomutase
BM526_06805	COG0058	SHG alpha-glucan phosphorylase activity
BM526_06815	COG2988	succinylglutamate desuccinylase activity
BM526_06850	COG1393	Belongs to the ArsC family
BM526_06875	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BM526_06900	COG2080	2 iron, 2 sulfur cluster binding
BM526_06910	COG0281	malic enzyme
BM526_06915	COG5001	Diguanylate cyclase
BM526_06915	COG3300	MHYT domain
BM526_06940	COG2249	NAD(P)H dehydrogenase (quinone) activity
BM526_06960	COG1733	regulation of RNA biosynthetic process
BM526_06965	COG5001	Diguanylate cyclase
BM526_06965	COG5002	protein histidine kinase activity
BM526_06965	COG3447	MASE1 domain protein
BM526_06975	COG0402	S-adenosylhomocysteine deaminase activity
BM526_06980	COG2351	hydroxyisourate hydrolase activity
BM526_06995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM526_07005	COG1309	transcriptional regulator
BM526_07020	COG2252	PERMEase
BM526_07025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BM526_07040	COG3706	GGDEF domain
BM526_07040	COG0745	RESPONSE REGULATOR receiver
BM526_07045	COG0784	Response regulator, receiver
BM526_07045	COG2205	protein histidine kinase activity
BM526_07060	COG2233	PERMEase
BM526_07080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM526_07085	COG0730	response to heat
BM526_07125	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_07140	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BM526_07155	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BM526_07155	COG0662	Cupin 2, conserved barrel domain protein
BM526_07160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BM526_07170	COG1596	polysaccharide export
BM526_07175	COG0489	protein tyrosine kinase activity
BM526_07180	COG4464	protein tyrosine phosphatase activity
BM526_07215	COG0297	glycogen (starch) synthase activity
BM526_07280	COG2246	polysaccharide biosynthetic process
BM526_07285	COG0463	Glycosyl transferase, family 2
BM526_07300	COG2963	transposase activity
BM526_07330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM526_07330	COG0072	phenylalanine-tRNA ligase activity
BM526_07355	COG1472	Belongs to the glycosyl hydrolase 3 family
BM526_07360	COG2096	Adenosyltransferase
BM526_07370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BM526_07380	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM526_07405	COG0708	Exodeoxyribonuclease III
BM526_07440	COG2814	Major facilitator Superfamily
BM526_07480	COG1024	Enoyl-CoA hydratase
BM526_07485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM526_07490	COG1960	acyl-CoA dehydrogenase activity
BM526_07495	COG0789	Transcriptional regulator
BM526_07500	COG0183	Belongs to the thiolase family
BM526_07515	COG3706	GGDEF domain
BM526_07525	COG2925	Exonuclease
BM526_07575	COG1643	Atp-dependent helicase
BM526_07595	COG3321	synthase
BM526_07595	COG0604	alcohol dehydrogenase
BM526_07600	COG0328	RNA-DNA hybrid ribonuclease activity
BM526_07605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM526_07635	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BM526_07645	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM526_07660	COG3724	N-succinylarginine dihydrolase activity
BM526_07670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BM526_07685	COG0746	molybdenum cofactor guanylyltransferase activity
BM526_07690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BM526_07695	COG0243	molybdopterin cofactor binding
BM526_07700	COG2153	protein acetylation
BM526_07715	COG1530	ribonuclease E activity
BM526_07735	COG1399	metal-binding, possibly nucleic acid-binding protein
BM526_07745	COG0416	fatty acid biosynthetic process
BM526_07750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BM526_07755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BM526_07765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM526_07770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM526_07775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BM526_07780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BM526_07795	COG0084	hydrolase, TatD family'
BM526_07805	COG0702	epimerase
BM526_07810	COG0745	RESPONSE REGULATOR receiver
BM526_07810	COG3706	GGDEF domain
BM526_07830	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_07835	COG0596	Alpha beta hydrolase
BM526_07845	COG0183	Belongs to the thiolase family
BM526_07850	COG1960	acyl-CoA dehydrogenase activity
BM526_07870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_07880	COG0246	Mannitol dehydrogenase
BM526_07905	COG0668	transmembrane transport
BM526_07910	COG4771	TonB-dependent receptor
BM526_07940	COG3437	response regulator, receiver
BM526_07950	COG0195	Participates in both transcription termination and antitermination
BM526_07965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BM526_07980	COG3300	MHYT domain
BM526_07980	COG5001	Diguanylate cyclase
BM526_07985	COG1187	pseudouridine synthase activity
BM526_07995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM526_07995	COG3153	acetyltransferase
BM526_08025	COG0450	alkyl hydroperoxide reductase
BM526_08070	COG1032	radical SAM domain protein
BM526_08085	COG4771	TonB-dependent receptor
BM526_08090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_08100	COG4134	Bacterial extracellular solute-binding protein
BM526_08110	COG4136	ATPase activity
BM526_08115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BM526_08135	COG4251	negative regulation of phosphorylation
BM526_08135	COG5001	Diguanylate cyclase
BM526_08135	COG2203	Gaf domain
BM526_08135	COG3706	GGDEF domain
BM526_08155	COG0583	DNA-binding transcription factor activity
BM526_08175	COG1131	(ABC) transporter
BM526_08190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM526_08195	COG0385	Bile acid
BM526_08225	COG0582	viral genome integration into host DNA
BM526_08300	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BM526_08305	COG0732	type I restriction modification DNA specificity domain
BM526_08320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BM526_08365	COG1902	pentaerythritol trinitrate reductase activity
BM526_08375	COG2867	negative regulation of translational initiation
BM526_08380	COG2914	Belongs to the UPF0125 (RnfH) family
BM526_08390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM526_08395	COG4771	TonB-dependent receptor
BM526_08400	COG0457	Tetratricopeptide repeat
BM526_08415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BM526_08415	COG0574	Belongs to the PEP-utilizing enzyme family
BM526_08450	COG2850	peptidyl-arginine hydroxylation
BM526_08460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BM526_08465	COG2915	High frequency lysogenization protein hflD homolog
BM526_08470	COG0482	sulfurtransferase activity
BM526_08475	COG1187	pseudouridine synthase activity
BM526_08485	COG1278	Cold shock
BM526_08490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BM526_08495	COG0542	response to heat
BM526_08500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BM526_08505	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BM526_08510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BM526_08515	COG0492	ferredoxin-NADP+ reductase activity
BM526_08520	COG3092	negative regulation of chromosome organization
BM526_08525	COG3091	SprT-like family
BM526_08530	COG0616	signal peptide processing
BM526_08545	COG0778	Nitroreductase
BM526_08555	COG0252	asparaginase activity
BM526_08560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BM526_08565	COG0321	lipoyl(octanoyl) transferase activity
BM526_08570	COG2921	Belongs to the UPF0250 family
BM526_08575	COG1686	Belongs to the peptidase S11 family
BM526_08580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM526_08585	COG0772	Belongs to the SEDS family
BM526_08590	COG0768	penicillin binding
BM526_08595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BM526_08600	COG0799	negative regulation of ribosome biogenesis
BM526_08610	COG1466	dna polymerase III delta subunit
BM526_08615	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BM526_08620	COG0495	leucyl-tRNA aminoacylation
BM526_08630	COG1067	ATP-dependent peptidase activity
BM526_08635	COG0596	Alpha beta hydrolase
BM526_08640	COG3706	GGDEF domain
BM526_08650	COG1534	Rna-binding protein
BM526_08655	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BM526_08660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM526_08665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BM526_08670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BM526_08675	COG0149	triose-phosphate isomerase activity
BM526_08680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM526_08710	COG1803	Methylglyoxal synthase
BM526_08710	COG1597	lipid kinase activity
BM526_08720	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_08725	COG0561	phosphatase activity
BM526_08740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_08765	COG1185	polyribonucleotide nucleotidyltransferase activity
BM526_08880	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BM526_08885	COG1196	nuclear chromosome segregation
BM526_08895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BM526_08910	COG1132	(ABC) transporter
BM526_08915	COG1663	tetraacyldisaccharide 4'-kinase activity
BM526_08955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BM526_08960	COG0435	Glutathione S-transferase
BM526_08965	COG1741	Belongs to the pirin family
BM526_08970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BM526_08980	COG0372	Belongs to the citrate synthase family
BM526_08985	COG2009	succinate dehydrogenase
BM526_08990	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BM526_08995	COG1053	succinate dehydrogenase
BM526_09000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BM526_09005	COG0567	Dehydrogenase, E1 component
BM526_09010	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM526_09065	COG4667	esterase of the alpha-beta hydrolase superfamily
BM526_09085	COG0366	Alpha amylase catalytic
BM526_09110	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_09115	COG2267	carboxylic ester hydrolase activity
BM526_09125	COG0616	signal peptide processing
BM526_09145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM526_09150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM526_09155	COG0386	Belongs to the glutathione peroxidase family
BM526_09160	COG2084	Dehydrogenase
BM526_09170	COG1960	acyl-CoA dehydrogenase activity
BM526_09175	COG1024	Enoyl-CoA hydratase
BM526_09180	COG2226	methyltransferase
BM526_09185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM526_09190	COG3083	sulfuric ester hydrolase activity
BM526_09195	COG3082	Protein of unknown function (DUF1414)
BM526_09200	COG3081	Nucleoid-associated protein
BM526_09230	COG3275	phosphorelay sensor kinase activity
BM526_09235	COG3279	Response regulator of the LytR AlgR family
BM526_09240	COG0205	6-phosphofructokinase activity
BM526_09250	COG0789	Transcriptional regulator
BM526_09300	COG2205	protein histidine kinase activity
BM526_09300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_09320	COG0513	Belongs to the DEAD box helicase family
BM526_09330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BM526_09335	COG0583	DNA-binding transcription factor activity
BM526_09355	COG1760	l-serine dehydratase
BM526_09375	COG1322	Protein conserved in bacteria
BM526_09380	COG1404	Belongs to the peptidase S8 family
BM526_09385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BM526_09390	COG0022	dehydrogenase e1 component
BM526_09400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BM526_09405	COG0515	serine threonine protein kinase
BM526_09410	COG1946	Acyl-CoA thioesterase
BM526_09420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM526_09430	COG1956	GAF domain-containing protein
BM526_09445	COG0793	Belongs to the peptidase S41A family
BM526_09450	COG0733	neurotransmitter:sodium symporter activity
BM526_09460	COG0308	aminopeptidase N
BM526_09490	COG2902	Dehydrogenase
BM526_09495	COG0167	dihydroorotate dehydrogenase activity
BM526_09520	COG3130	regulation of translation
BM526_09525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM526_09535	COG0415	Belongs to the DNA photolyase family
BM526_09540	COG0415	Belongs to the DNA photolyase family
BM526_09545	COG0415	Belongs to the DNA photolyase family
BM526_09550	COG3046	protein related to deoxyribodipyrimidine photolyase
BM526_09565	COG4264	IucA IucC family
BM526_09570	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_09575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM526_09580	COG1082	Xylose isomerase domain protein TIM barrel
BM526_09605	COG4974	Belongs to the 'phage' integrase family
BM526_09615	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BM526_09620	COG0589	response to stress
BM526_09630	COG0069	glutamate synthase activity
BM526_09645	COG2193	ferroxidase activity
BM526_09655	COG3278	Belongs to the heme-copper respiratory oxidase family
BM526_09670	COG2010	Cytochrome c
BM526_09680	COG2217	Heavy metal translocating P-type atpase
BM526_09695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM526_09700	COG0589	response to stress
BM526_09705	COG0037	tRNA processing
BM526_09710	COG1752	Esterase of the alpha-beta hydrolase superfamily
BM526_09730	COG1280	lysine exporter protein (LysE YggA)
BM526_09735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BM526_09740	COG2897	thiosulfate sulfurtransferase activity
BM526_09745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BM526_09775	COG0322	excinuclease ABC activity
BM526_09780	COG2197	response regulator
BM526_09785	COG0436	Aminotransferase
BM526_09815	COG2259	Doxx family
BM526_09820	COG0583	DNA-binding transcription factor activity
BM526_09840	COG0670	Belongs to the BI1 family
BM526_09845	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BM526_09860	COG2920	part of a sulfur-relay system
BM526_09890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BM526_09900	COG1674	ftsk spoiiie
BM526_09900	COG0531	amino acid
BM526_09910	COG0686	Belongs to the AlaDH PNT family
BM526_09915	COG0284	orotidine-5'-phosphate decarboxylase activity
BM526_09920	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BM526_09935	COG0776	regulation of translation
BM526_09940	COG0539	negative regulation of cytoplasmic translation
BM526_09945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BM526_09950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BM526_09955	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BM526_09965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM526_09970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM526_09975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM526_09980	COG0633	Ferredoxin
BM526_10010	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BM526_10015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BM526_10025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM526_10035	COG4783	chaperone-mediated protein folding
BM526_10045	COG1393	Belongs to the ArsC family
BM526_10060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM526_10075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BM526_10085	COG1960	acyl-CoA dehydrogenase activity
BM526_10110	COG0572	uridine kinase
BM526_10115	COG3769	mannosylglycerate metabolic process
BM526_10120	COG1215	transferase activity, transferring glycosyl groups
BM526_10125	COG0366	Alpha amylase catalytic
BM526_10135	COG0303	'Molybdopterin
BM526_10140	COG0534	Mate efflux family protein
BM526_10155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM526_10160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM526_10290	COG0405	Gamma-glutamyltransferase
BM526_10295	COG1024	Enoyl-CoA hydratase
BM526_10340	COG1448	Aminotransferase
BM526_10355	COG1671	Belongs to the UPF0178 family
BM526_10360	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_10365	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_10370	COG1960	acyl-CoA dehydrogenase activity
BM526_10375	COG0662	Cupin 2, conserved barrel domain protein
BM526_10375	COG2207	Transcriptional regulator
BM526_10380	COG4771	TonB-dependent receptor
BM526_10390	COG1505	serine-type exopeptidase activity
BM526_10400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_10430	COG0596	Alpha beta hydrolase
BM526_10440	COG0716	FMN binding
BM526_10450	COG0735	belongs to the Fur family
BM526_10460	COG1984	allophanate hydrolase subunit 2
BM526_10465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BM526_10470	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BM526_10475	COG2996	Protein conserved in bacteria
BM526_10480	COG1765	OsmC-like protein
BM526_10485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_10495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_10510	COG0436	Aminotransferase
BM526_10515	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM526_10520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BM526_10545	COG3012	SEC-C Motif Domain Protein
BM526_10550	COG3447	MASE1 domain protein
BM526_10550	COG5001	Diguanylate cyclase
BM526_10550	COG5002	protein histidine kinase activity
BM526_10555	COG0366	Alpha amylase catalytic
BM526_10565	COG0604	alcohol dehydrogenase
BM526_10575	COG1960	acyl-CoA dehydrogenase activity
BM526_10585	COG4771	TonB-dependent receptor
BM526_10605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM526_10610	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BM526_10610	COG1618	nucleotide phosphatase activity, acting on free nucleotides
BM526_10630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BM526_10640	COG0521	Mo-molybdopterin cofactor biosynthetic process
BM526_10645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BM526_10675	COG0436	Aminotransferase
BM526_10680	COG3268	Saccharopine dehydrogenase
BM526_10685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM526_10705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BM526_10710	COG4206	TonB-dependent receptor
BM526_10720	COG5006	permease, DMT superfamily
BM526_10745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM526_10750	COG1074	ATP-dependent DNA helicase activity
BM526_10755	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BM526_10770	COG1022	Amp-dependent synthetase and ligase
BM526_10775	COG2203	Gaf domain
BM526_10775	COG3706	GGDEF domain
BM526_10775	COG4251	negative regulation of phosphorylation
BM526_10775	COG5001	Diguanylate cyclase
BM526_10795	COG0583	DNA-binding transcription factor activity
BM526_10810	COG0640	Transcriptional regulator
BM526_10830	COG2204	response regulator
BM526_10840	COG4251	negative regulation of phosphorylation
BM526_10845	COG0784	Response regulator, receiver
BM526_10850	COG0784	Response regulator, receiver
BM526_10850	COG2205	protein histidine kinase activity
BM526_10875	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM526_10900	COG3139	Protein of unknown function (DUF1315)
BM526_10915	COG1115	amino acid carrier protein
BM526_10920	COG2866	Carboxypeptidase
BM526_10940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BM526_10950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BM526_10955	COG1640	4-alpha-glucanotransferase
BM526_10960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BM526_10965	COG0676	glucose-6-phosphate 1-epimerase activity
BM526_10970	COG0800	Aldolase
BM526_10980	COG0129	dihydroxy-acid dehydratase activity
BM526_10990	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BM526_10995	COG1737	Transcriptional regulator
BM526_11000	COG0469	pyruvate kinase activity
BM526_11005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM526_11020	COG2823	Periplasmic or secreted lipoprotein
BM526_11050	COG3665	Urea carboxylase-associated protein
BM526_11070	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_11085	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BM526_11100	COG2721	sulfolactate sulfo-lyase activity
BM526_11105	COG1904	glucuronate isomerase
BM526_11110	COG0246	Mannitol dehydrogenase
BM526_11115	COG0800	Aldolase
BM526_11120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_11125	COG2755	lipolytic protein G-D-S-L family
BM526_11135	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BM526_11160	COG2356	endonuclease I
BM526_11165	COG0840	transmembrane signaling receptor activity
BM526_11180	COG0583	DNA-binding transcription factor activity
BM526_11185	COG1979	alcohol dehydrogenase
BM526_11190	COG5001	Diguanylate cyclase
BM526_11200	COG0784	Response regulator, receiver
BM526_11200	COG3437	response regulator, receiver
BM526_11205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM526_11205	COG4191	Histidine kinase
BM526_11240	COG0471	metal ion transport
BM526_11250	COG0489	protein tyrosine kinase activity
BM526_11255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM526_11255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM526_11260	COG0668	transmembrane transport
BM526_11265	COG2226	methyltransferase
BM526_11275	COG1388	LysM domain
BM526_11275	COG0741	lytic transglycosylase activity
BM526_11300	COG0215	cysteine-tRNA ligase activity
BM526_11305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM526_11310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM526_11320	COG2268	Band 7 protein
BM526_11335	COG1733	regulation of RNA biosynthetic process
BM526_11340	COG0604	alcohol dehydrogenase
BM526_11345	COG0753	catalase activity
BM526_11350	COG0604	alcohol dehydrogenase
BM526_11355	COG0583	DNA-binding transcription factor activity
BM526_11380	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BM526_11385	COG1286	toxin biosynthetic process
BM526_11390	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BM526_11395	COG0285	dihydrofolate synthase activity
BM526_11415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BM526_11420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM526_11440	COG3609	addiction module antidote protein, CC2985 family
BM526_11445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM526_11450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM526_11455	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_11465	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BM526_11465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM526_11500	COG0789	Transcriptional regulator
BM526_11505	COG0604	alcohol dehydrogenase
BM526_11520	COG1119	ATPase activity
BM526_11525	COG2031	fatty acid transporter
BM526_11530	COG5002	protein histidine kinase activity
BM526_11530	COG0784	Response regulator, receiver
BM526_11530	COG2205	protein histidine kinase activity
BM526_11540	COG0612	Peptidase, M16
BM526_11555	COG3101	peptidyl-lysine hydroxylation
BM526_11580	COG1902	pentaerythritol trinitrate reductase activity
BM526_11580	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM526_11605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM526_11615	COG4399	Belongs to the UPF0754 family
BM526_11640	COG1770	oligopeptidase
BM526_11645	COG2186	Transcriptional regulator
BM526_11655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BM526_11660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BM526_11670	COG2983	Belongs to the UPF0260 family
BM526_11675	COG0179	Fumarylacetoacetate (FAA) hydrolase
BM526_11690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BM526_11695	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_11700	COG2267	carboxylic ester hydrolase activity
BM526_11715	COG1214	PFAM Peptidase M22, glycoprotease
BM526_11720	COG1199	ATP-dependent helicase activity
BM526_11780	COG4771	TonB-dependent receptor
BM526_11790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BM526_11795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BM526_11800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM526_11805	COG0131	Imidazoleglycerol-phosphate dehydratase
BM526_11805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM526_11810	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BM526_11825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BM526_11825	COG0140	phosphoribosyl-ATP diphosphatase activity
BM526_11830	COG2116	formate transmembrane transporter activity
BM526_11865	COG0326	Molecular chaperone. Has ATPase activity
BM526_11870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BM526_11890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BM526_11895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BM526_11905	COG3220	belongs to the UPF0276 family
BM526_11915	COG0577	efflux transmembrane transporter activity
BM526_11915	COG1136	(ABC) transporter
BM526_11925	COG4251	negative regulation of phosphorylation
BM526_11925	COG5001	Diguanylate cyclase
BM526_11925	COG2203	Gaf domain
BM526_11925	COG3706	GGDEF domain
BM526_11960	COG1183	phosphatidylcholine synthase activity
BM526_11980	COG0277	FAD linked oxidase domain protein
BM526_11985	COG0542	response to heat
BM526_11995	COG0564	pseudouridine synthase activity
BM526_12010	COG1595	DNA-templated transcription, initiation
BM526_12025	COG4221	oxidoreductase activity
BM526_12040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BM526_12050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BM526_12060	COG0142	geranyltranstransferase activity
BM526_12070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BM526_12075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BM526_12085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BM526_12100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM526_12100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM526_12120	COG0488	(ABC) transporter
BM526_12130	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BM526_12140	COG0560	Phosphoserine phosphatase
BM526_12150	COG0084	hydrolase, TatD family'
BM526_12165	COG0571	ribonuclease III activity
BM526_12170	COG0681	Belongs to the peptidase S26 family
BM526_12195	COG1595	DNA-templated transcription, initiation
BM526_12200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BM526_12215	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BM526_12295	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BM526_12300	COG1047	Peptidyl-prolyl cis-trans
BM526_12310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BM526_12315	COG0196	riboflavin kinase activity
BM526_12320	COG0728	peptidoglycan biosynthetic process
BM526_12325	COG0268	Binds directly to 16S ribosomal RNA
BM526_12340	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_12345	COG0385	Bile acid
BM526_12350	COG0583	DNA-binding transcription factor activity
BM526_12375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM526_12380	COG0776	regulation of translation
BM526_12385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM526_12390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BM526_12395	COG0740	serine-type endopeptidase activity
BM526_12400	COG0544	peptidyl-prolyl cis-trans isomerase activity
BM526_12455	COG1720	tRNA m6t6A37 methyltransferase activity
BM526_12465	COG1234	tRNA 3'-trailer cleavage
BM526_12475	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM526_12490	COG0517	IMP dehydrogenase activity
BM526_12490	COG0516	GMP reductase activity
BM526_12495	COG1570	exodeoxyribonuclease VII activity
BM526_12520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM526_12525	COG2976	Protein conserved in bacteria
BM526_12550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BM526_12560	COG2166	iron-sulfur cluster assembly
BM526_12575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BM526_12580	COG0719	Fe-S assembly protein
BM526_12585	COG0396	ATPase activity
BM526_12590	COG0719	Fe-S assembly protein
BM526_12595	COG1104	cysteine desulfurase activity
BM526_12600	COG1959	2 iron, 2 sulfur cluster binding
BM526_12605	COG2072	flavoprotein involved in K transport
BM526_12615	COG1045	serine acetyltransferase
BM526_12620	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BM526_12625	COG0483	inositol monophosphate 1-phosphatase activity
BM526_12640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM526_12645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM526_12650	COG1862	Preprotein translocase
BM526_12655	COG0343	queuine tRNA-ribosyltransferase activity
BM526_12675	COG1842	Phage shock protein A
BM526_12680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BM526_12700	COG0754	glutathionylspermidine amidase activity
BM526_12730	COG2066	Belongs to the glutaminase family
BM526_12735	COG1785	Belongs to the alkaline phosphatase family
BM526_12825	COG1215	transferase activity, transferring glycosyl groups
BM526_12845	COG1215	transferase activity, transferring glycosyl groups
BM526_12850	COG0463	Glycosyl transferase, family 2
BM526_12865	COG1216	Glycosyl transferase, family 2
BM526_12870	COG1216	Glycosyl transferase, family 2
BM526_12870	COG0463	Glycosyl transferase, family 2
BM526_12880	COG0297	glycogen (starch) synthase activity
BM526_12895	COG0438	transferase activity, transferring glycosyl groups
BM526_12915	COG0438	transferase activity, transferring glycosyl groups
BM526_12915	COG0297	glycogen (starch) synthase activity
BM526_12935	COG0489	protein tyrosine kinase activity
BM526_12955	COG3409	Peptidoglycan-binding domain 1 protein
BM526_12955	COG3267	Type II secretory pathway component ExeA
BM526_12960	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BM526_12960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM526_12990	COG1560	Kdo2-lipid A biosynthetic process
BM526_13005	COG1960	acyl-CoA dehydrogenase activity
BM526_13020	COG3300	MHYT domain
BM526_13020	COG5001	Diguanylate cyclase
BM526_13025	COG1435	thymidine kinase activity
BM526_13035	COG1609	Transcriptional regulator
BM526_13040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BM526_13075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM526_13080	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM526_13080	COG1024	Enoyl-CoA hydratase
BM526_13095	COG1012	belongs to the aldehyde dehydrogenase family
BM526_13115	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BM526_13120	COG0789	Transcriptional regulator
BM526_13150	COG1960	acyl-CoA dehydrogenase activity
BM526_13170	COG0745	RESPONSE REGULATOR receiver
BM526_13175	COG2205	protein histidine kinase activity
BM526_13220	COG2080	2 iron, 2 sulfur cluster binding
BM526_13225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BM526_13230	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM526_13250	COG1028	Short-chain dehydrogenase reductase Sdr
BM526_13255	COG4221	oxidoreductase activity
BM526_13260	COG0693	protein deglycase activity
BM526_13265	COG1295	ribonuclease BN
BM526_13280	COG4681	YaeQ
BM526_13310	COG2814	Major facilitator Superfamily
BM526_13335	COG0514	ATP-dependent DNA helicase (RecQ)
BM526_13360	COG3706	GGDEF domain
BM526_13375	COG4251	negative regulation of phosphorylation
BM526_13380	COG2133	pyrroloquinoline quinone binding
BM526_13385	COG3609	addiction module antidote protein, CC2985 family
BM526_13400	COG5002	protein histidine kinase activity
BM526_13445	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BM526_13450	COG2971	BadF BadG BcrA BcrD
BM526_13455	COG0583	DNA-binding transcription factor activity
BM526_13460	COG1620	l-lactate permease
BM526_13485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM526_13490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM526_13495	COG0006	proline dipeptidase activity
BM526_13510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_13525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BM526_13530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BM526_13535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM526_13555	COG3313	Fe-S protein
BM526_13590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_13595	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM526_13600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BM526_13605	COG2186	Transcriptional regulator
BM526_13615	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM526_13620	COG3577	Aspartyl protease
BM526_13625	COG0157	Belongs to the NadC ModD family
BM526_13635	COG1459	type II secretion system
BM526_13640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BM526_13645	COG0237	dephospho-CoA kinase activity
BM526_13645	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BM526_13650	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BM526_13660	COG3608	succinylglutamate desuccinylase aspartoacylase
BM526_13665	COG0494	nUDIX hydrolase
BM526_13675	COG0739	heme binding
BM526_13680	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BM526_13685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BM526_13690	COG0849	cell division
BM526_13695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BM526_13700	COG1181	Belongs to the D-alanine--D-alanine ligase family
BM526_13705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM526_13715	COG0772	Belongs to the SEDS family
BM526_13720	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BM526_13730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BM526_13735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BM526_13740	COG0768	penicillin binding
BM526_13745	COG3116	cell division
BM526_13755	COG2001	Belongs to the MraZ family
BM526_13775	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM526_13800	COG0678	peroxiredoxin activity
BM526_13800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM526_13815	COG3706	GGDEF domain
BM526_13825	COG2204	response regulator
BM526_13830	COG0784	Response regulator, receiver
BM526_13830	COG2205	protein histidine kinase activity
BM526_13845	COG2271	Major facilitator Superfamily
BM526_13870	COG0668	transmembrane transport
BM526_13875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BM526_13880	COG0189	ligase activity
BM526_13885	COG1678	Uncharacterized ACR, COG1678
BM526_13890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BM526_13915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BM526_13920	COG0762	integral membrane protein
BM526_13930	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM526_13930	COG1902	pentaerythritol trinitrate reductase activity
BM526_13945	COG0625	glutathione transferase activity
BM526_13955	COG1764	response to oxidative stress
BM526_13970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BM526_13980	COG2814	Major facilitator Superfamily
BM526_13985	COG0724	RNA recognition motif
BM526_14010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BM526_14015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BM526_14020	COG0083	homoserine kinase activity
BM526_14035	COG0583	DNA-binding transcription factor activity
BM526_14050	COG0640	Transcriptional regulator
BM526_14060	COG0431	NADPH-dependent FMN reductase
BM526_14065	COG0798	PFAM Bile acid sodium symporter
BM526_14070	COG2201	protein-glutamate methylesterase activity
BM526_14075	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BM526_14085	COG0642	Histidine kinase
BM526_14100	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BM526_14130	COG1748	Saccharopine dehydrogenase
BM526_14145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BM526_14150	COG3107	peptidoglycan biosynthetic process
BM526_14170	COG2823	Periplasmic or secreted lipoprotein
BM526_14190	COG4585	Histidine kinase
BM526_14195	COG2197	response regulator
BM526_14205	COG4771	TonB-dependent receptor
BM526_14215	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BM526_14220	COG0372	Belongs to the citrate synthase family
BM526_14225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BM526_14230	COG2828	Protein conserved in bacteria
BM526_14235	COG2203	Gaf domain
BM526_14235	COG2199	diguanylate cyclase activity
BM526_14255	COG2198	Histidine kinase
BM526_14255	COG5002	protein histidine kinase activity
BM526_14255	COG0784	Response regulator, receiver
BM526_14260	COG3023	N-Acetylmuramoyl-L-alanine amidase
BM526_14265	COG0067	glutamate synthase
BM526_14265	COG0069	glutamate synthase activity
BM526_14265	COG0070	glutamate synthase
BM526_14270	COG0493	'glutamate synthase
BM526_14290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM526_14295	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BM526_14300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BM526_14305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM526_14320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM526_14325	COG5507	3-demethylubiquinone-9 3-methyltransferase
BM526_14330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BM526_14335	COG4942	peptidase
BM526_14340	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BM526_14345	COG0738	Major facilitator superfamily
BM526_14355	COG1902	pentaerythritol trinitrate reductase activity
BM526_14375	COG0625	glutathione transferase activity
BM526_14400	COG2894	cell division
BM526_14405	COG0850	regulation of cytokinetic process
BM526_14415	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BM526_14450	COG1914	H( )-stimulated, divalent metal cation uptake system
BM526_14455	COG0436	Aminotransferase
BM526_14470	COG0174	glutamine synthetase
BM526_14480	COG3852	Histidine kinase
BM526_14485	COG2204	response regulator
BM526_14490	COG3437	response regulator, receiver
BM526_14495	COG0204	Acyl-transferase
BM526_14510	COG3706	GGDEF domain
BM526_14530	COG2205	protein histidine kinase activity
BM526_14530	COG3437	response regulator, receiver
BM526_14530	COG3850	Histidine kinase
BM526_14530	COG4999	Histidine kinase
BM526_14535	COG0525	valine-tRNA ligase activity
BM526_14540	COG2927	DNA polymerase III (CHI subunit)
BM526_14545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM526_14550	COG0795	lipopolysaccharide-transporting ATPase activity
BM526_14555	COG0795	lipopolysaccharide-transporting ATPase activity
BM526_14630	COG3459	Glycosyltransferase 36 associated
BM526_14640	COG2203	Gaf domain
BM526_14640	COG2199	diguanylate cyclase activity
BM526_14670	COG0673	inositol 2-dehydrogenase activity
BM526_14675	COG5002	protein histidine kinase activity
BM526_14680	COG0628	permease
BM526_14695	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BM526_14700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BM526_14705	COG4558	Periplasmic binding protein
BM526_14715	COG4206	TonB-dependent receptor
BM526_14725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BM526_14730	COG0697	spore germination
BM526_14760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BM526_14770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BM526_14775	COG0745	RESPONSE REGULATOR receiver
BM526_14775	COG3706	GGDEF domain
BM526_14780	COG0679	Auxin Efflux Carrier
BM526_14790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM526_14800	COG0395	ABC-type sugar transport system, permease component
BM526_14820	COG2267	carboxylic ester hydrolase activity
BM526_14850	COG1131	(ABC) transporter
BM526_14860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM526_14910	COG2205	protein histidine kinase activity
BM526_14920	COG3901	Regulator of nitric oxide reductase transcription
BM526_14920	COG0348	domain, Protein
BM526_14930	COG2197	response regulator
BM526_14965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM526_14970	COG0277	FAD linked oxidase domain protein
BM526_14980	COG1462	curli production assembly transport component CsgG
BM526_15010	COG2197	response regulator
BM526_15035	COG0513	Belongs to the DEAD box helicase family
BM526_15040	COG5001	Diguanylate cyclase
BM526_15045	COG0800	Aldolase
BM526_15050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_15065	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BM526_15065	COG3264	Mechanosensitive ion channel
BM526_15105	COG0730	response to heat
BM526_15125	COG4191	Histidine kinase
BM526_15135	COG0417	DNA replication proofreading
BM526_15145	COG0318	PFAM AMP-dependent synthetase and ligase
BM526_15195	COG1309	transcriptional regulator
BM526_15205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_15215	COG1573	uracil-dna glycosylase
BM526_15220	COG5001	Diguanylate cyclase
BM526_15220	COG3300	MHYT domain
BM526_15240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM526_15260	COG1983	PspC domain protein
BM526_15265	COG1842	Phage shock protein A
BM526_15275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM526_15280	COG0582	viral genome integration into host DNA
BM526_15360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BM526_15365	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BM526_15445	COG1621	beta-fructofuranosidase activity
BM526_15465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM526_15475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BM526_15480	COG0204	Acyl-transferase
BM526_15485	COG0204	Acyl-transferase
BM526_15490	COG0668	transmembrane transport
BM526_15505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM526_15510	COG0733	neurotransmitter:sodium symporter activity
BM526_15525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BM526_15540	COG0716	FMN binding
BM526_15550	COG0848	biopolymer transport protein
BM526_15565	COG0457	Tetratricopeptide repeat
BM526_15570	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BM526_15580	COG1215	transferase activity, transferring glycosyl groups
BM526_15595	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BM526_15615	COG5001	Diguanylate cyclase
BM526_15615	COG5002	protein histidine kinase activity
BM526_15625	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BM526_15635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM526_15645	COG0583	DNA-binding transcription factor activity
BM526_15650	COG0121	glutamine amidotransferase
BM526_15660	COG4682	membrane
BM526_15680	COG1953	Uracil, thiamine, allantoin
BM526_15685	COG4771	TonB-dependent receptor
BM526_15695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM526_15705	COG0596	Alpha beta hydrolase
BM526_15710	COG0251	oxidation-reduction process
BM526_15715	COG1335	isochorismatase
BM526_15720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM526_15725	COG1309	transcriptional regulator
BM526_15740	COG4628	conserved protein (DUF2132)
BM526_15745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM526_15755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BM526_15775	COG1477	protein flavinylation
BM526_15780	COG2871	sodium ion transport
BM526_15785	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_15790	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_15795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_15800	COG1805	sodium ion transport
BM526_15805	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM526_15810	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BM526_15815	COG0545	Peptidyl-prolyl cis-trans isomerase
BM526_15820	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BM526_15835	COG0039	L-malate dehydrogenase activity
BM526_15840	COG1438	arginine binding
BM526_15865	COG0572	uridine kinase
BM526_15870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BM526_15885	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BM526_15895	COG0745	RESPONSE REGULATOR receiver
BM526_15895	COG3706	GGDEF domain
BM526_15900	COG2176	DNA-directed DNA polymerase activity
BM526_15910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_15920	COG2205	protein histidine kinase activity
BM526_15930	COG0189	ligase activity
BM526_15940	COG0189	ligase activity
BM526_15940	COG4067	protein conserved in archaea
BM526_15965	COG1283	sodium-dependent phosphate transmembrane transporter activity
BM526_15970	COG0667	Aldo Keto reductase
BM526_15995	COG2815	serine threonine protein kinase
BM526_15995	COG0515	serine threonine protein kinase
BM526_16070	COG2274	protein secretion by the type I secretion system
BM526_16075	COG0583	DNA-binding transcription factor activity
BM526_16110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM526_16125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BM526_16145	COG1063	alcohol dehydrogenase
BM526_16175	COG2244	polysaccharide biosynthetic process
BM526_16195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BM526_16205	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BM526_16210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BM526_16225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM526_16240	COG0202	RNA polymerase activity
BM526_16265	COG0201	protein transport
BM526_16285	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BM526_16320	COG5002	protein histidine kinase activity
BM526_16320	COG0784	Response regulator, receiver
BM526_16340	COG0557	exoribonuclease II activity
BM526_16385	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BM526_16400	COG0543	2 iron, 2 sulfur cluster binding
BM526_16410	COG2234	aminopeptidase activity
BM526_16420	COG4251	negative regulation of phosphorylation
BM526_16430	COG1271	oxidase subunit
BM526_16435	COG1294	oxidase, subunit
BM526_16440	COG1522	sequence-specific DNA binding
BM526_16450	COG1278	Cold shock
BM526_16455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM526_16475	COG0339	signal peptide processing
BM526_16480	COG2201	protein-glutamate methylesterase activity
BM526_16490	COG3852	Histidine kinase
BM526_16500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM526_16505	COG0243	molybdopterin cofactor binding
BM526_16510	COG0823	Involved in the tonB-independent uptake of proteins
BM526_16510	COG1506	peptidase
BM526_16510	COG4946	Tricorn protease homolog
BM526_16555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM526_16565	COG2197	response regulator
BM526_16595	COG1621	beta-fructofuranosidase activity
BM526_16600	COG2814	Major facilitator Superfamily
BM526_16610	COG1629	transport
BM526_16610	COG4206	TonB-dependent receptor
BM526_16620	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BM526_16625	COG1278	Cold shock
BM526_16630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM526_16635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BM526_16650	COG0281	malic enzyme
BM526_16660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BM526_16690	COG0456	acetyltransferase
BM526_16700	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM526_16705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM526_16710	COG2177	Part of the ABC transporter FtsEX involved in
BM526_16715	COG2884	Cell division ATP-binding protein ftsE
BM526_16720	COG0552	protein localization to endoplasmic reticulum
BM526_16725	COG0742	ribosomal rna small subunit methyltransferase
BM526_16735	COG2095	MarC family integral membrane protein
BM526_16760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BM526_16765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM526_16770	COG0617	tRNA 3'-terminal CCA addition
BM526_16775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BM526_16790	COG0076	glutamate decarboxylase activity
BM526_16805	COG0842	Transport permease protein
BM526_16810	COG1131	(ABC) transporter
BM526_16815	COG0745	RESPONSE REGULATOR receiver
BM526_16820	COG2205	protein histidine kinase activity
BM526_16825	COG4774	siderophore transport
BM526_16850	COG1253	flavin adenine dinucleotide binding
BM526_16860	COG1966	Carbon starvation protein
BM526_16870	COG0657	acetylesterase activity
BM526_16915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BM526_16925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BM526_16955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BM526_16960	COG0049	tRNA binding
BM526_16965	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BM526_16970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BM526_16975	COG0085	RNA polymerase activity
BM526_16980	COG0222	ribosome binding
BM526_16985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BM526_16990	COG0081	regulation of translation
BM526_16995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BM526_17015	COG0250	Participates in transcription elongation, termination and antitermination
BM526_17020	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM526_17030	COG1132	(ABC) transporter
BM526_17035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BM526_17040	COG3590	peptidase
BM526_17050	COG0513	Belongs to the DEAD box helicase family
BM526_17055	COG0418	dihydroorotase activity
BM526_17060	COG3040	lipid binding
BM526_17065	COG4989	oxidoreductase activity
BM526_17070	COG0346	lactoylglutathione lyase activity
BM526_17075	COG0668	transmembrane transport
BM526_17095	COG0302	gtp cyclohydrolase
BM526_17105	COG2957	Belongs to the agmatine deiminase family
BM526_17110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM526_17120	COG1201	RNA secondary structure unwinding
BM526_17130	COG1793	dna ligase
BM526_17135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BM526_17140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM526_17150	COG1410	methionine synthase
BM526_17150	COG0646	methionine synthase
BM526_17155	COG0625	glutathione transferase activity
BM526_17160	COG0625	glutathione transferase activity
BM526_17170	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BM526_17185	COG1012	belongs to the aldehyde dehydrogenase family
BM526_17190	COG0028	Belongs to the TPP enzyme family
BM526_17200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BM526_17205	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BM526_17210	COG0330	HflC and HflK could
BM526_17215	COG0330	HflC and HflK could
BM526_17220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BM526_17225	COG1923	regulation of RNA biosynthetic process
BM526_17230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BM526_17245	COG0802	atpase or kinase
BM526_17250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BM526_17250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BM526_17255	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BM526_17265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BM526_17275	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BM526_17280	COG0735	belongs to the Fur family
BM526_17290	COG0432	Pfam Uncharacterised protein family UPF0047
BM526_17300	COG0305	Participates in initiation and elongation during chromosome replication
BM526_17325	COG2258	MOSC domain
BM526_17385	COG0784	Response regulator, receiver
BM526_17385	COG2198	Histidine kinase
BM526_17385	COG2205	protein histidine kinase activity
BM526_17395	COG1136	(ABC) transporter
BM526_17395	COG0577	efflux transmembrane transporter activity
BM526_17405	COG0840	transmembrane signaling receptor activity
BM526_17410	COG5002	protein histidine kinase activity
BM526_17415	COG0840	transmembrane signaling receptor activity
BM526_17430	COG2855	membrane
BM526_17435	COG2175	clavaminate synthase activity
BM526_17440	COG0656	L-ascorbic acid biosynthetic process
BM526_17460	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM526_17465	COG4771	TonB-dependent receptor
BM526_17490	COG1472	Belongs to the glycosyl hydrolase 3 family
BM526_17500	COG2723	6-phospho-beta-galactosidase activity
BM526_17505	COG1609	Transcriptional regulator
BM526_17510	COG0477	Major facilitator Superfamily
BM526_17510	COG2814	Major facilitator Superfamily
BM526_17515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM526_17520	COG4988	ABC transporter
BM526_17525	COG4890	Cyd operon protein YbgT
BM526_17530	COG1294	oxidase, subunit
BM526_17565	COG4319	ketosteroid isomerase
BM526_17580	COG2375	cellular response to nickel ion
BM526_17585	COG3237	CsbD-like
BM526_17600	COG1595	DNA-templated transcription, initiation
BM526_17605	COG1404	Belongs to the peptidase S8 family
BM526_17630	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM526_17630	COG0596	Alpha beta hydrolase
BM526_17650	COG3038	cytochrome b561
BM526_17660	COG1252	NADH dehydrogenase
BM526_17675	COG0583	DNA-binding transcription factor activity
BM526_17680	COG2067	long-chain fatty acid transport protein
BM526_17685	COG2130	NADP-dependent
BM526_17690	COG4251	negative regulation of phosphorylation
BM526_17690	COG2203	Gaf domain
BM526_17690	COG5001	Diguanylate cyclase
BM526_17690	COG3706	GGDEF domain
BM526_17695	COG2205	protein histidine kinase activity
BM526_17695	COG0784	Response regulator, receiver
BM526_17705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM526_17710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM526_17715	COG1349	DNA-binding transcription factor activity
BM526_17720	COG0673	inositol 2-dehydrogenase activity
BM526_17735	COG0697	spore germination
BM526_17740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BM526_17745	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BM526_17750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM526_17755	COG1166	arginine decarboxylase activity
BM526_17765	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BM526_17770	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BM526_17775	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BM526_17825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM526_17850	COG3866	Pectate lyase
BM526_17865	COG3030	protein affecting phage T7 exclusion by the F plasmid
BM526_17870	COG1324	tolerance protein
BM526_17875	COG4232	protein-disulfide reductase activity
BM526_17880	COG0739	heme binding
BM526_17885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BM526_17890	COG0511	ligase activity, forming carbon-carbon bonds
BM526_17895	COG0439	Biotin carboxylase
BM526_17940	COG0154	amidase activity
BM526_17955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM526_17960	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BM526_17975	COG0151	Belongs to the GarS family
BM526_17995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM526_18000	COG3954	Phosphoribulokinase
BM526_18010	COG0745	RESPONSE REGULATOR receiver
BM526_18025	COG1501	Belongs to the glycosyl hydrolase 31 family
BM526_18040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BM526_18050	COG3031	protein transport across the cell outer membrane
BM526_18060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_18065	COG1459	type II secretion system
BM526_18070	COG2165	general secretion pathway protein
BM526_18075	COG2165	general secretion pathway protein
BM526_18085	COG4795	General secretion pathway protein
BM526_18100	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BM526_18120	COG1012	belongs to the aldehyde dehydrogenase family
BM526_18130	COG1011	Hydrolase
BM526_18135	COG0494	nUDIX hydrolase
BM526_18140	COG1218	3'(2'),5'-bisphosphate nucleotidase
BM526_18155	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BM526_18165	COG3089	Belongs to the UPF0270 family
BM526_18170	COG0429	hydrolase of the alpha beta-hydrolase fold
BM526_18180	COG0488	(ABC) transporter
BM526_18205	COG0545	Peptidyl-prolyl cis-trans isomerase
BM526_18215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM526_18220	COG2183	response to ionizing radiation
BM526_18240	COG0596	Alpha beta hydrolase
BM526_18245	COG1040	competence protein
BM526_18265	COG1794	racemase activity, acting on amino acids and derivatives
BM526_18280	COG0534	Mate efflux family protein
BM526_18285	COG0726	polysaccharide deacetylase
BM526_18285	COG1649	PFAM Uncharacterised BCR, COG1649
BM526_18295	COG1999	signal sequence binding
BM526_18300	COG0109	protoheme IX farnesyltransferase activity
BM526_18305	COG1612	heme a metabolic process
BM526_18325	COG1845	cytochrome c oxidase, subunit III
BM526_18330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BM526_18335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BM526_18340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BM526_18360	COG0129	dihydroxy-acid dehydratase activity
BM526_18370	COG0606	chelatase, subunit chli
BM526_18375	COG0583	DNA-binding transcription factor activity
BM526_18385	COG2814	Major facilitator Superfamily
BM526_18390	COG1073	alpha beta
BM526_18395	COG0729	surface antigen
BM526_18400	COG2911	Protein conserved in bacteria
BM526_18425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM526_18435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BM526_18455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM526_18480	COG1228	amidohydrolase
BM526_18505	COG0425	Belongs to the sulfur carrier protein TusA family
BM526_18520	COG1561	YicC-like family, N-terminal region
BM526_18540	COG2723	6-phospho-beta-galactosidase activity
BM526_18545	COG2211	Major facilitator Superfamily
BM526_18550	COG1609	Transcriptional regulator
BM526_18565	COG2199	diguanylate cyclase activity
BM526_18565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BM526_18590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BM526_18610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BM526_18615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BM526_18635	COG1475	DNA binding
BM526_18640	COG1192	Involved in chromosome partitioning
BM526_18665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM526_18670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BM526_18680	COG0706	membrane insertase activity
BM526_18685	COG0594	ribonuclease P activity
BM526_18690	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BM526_18795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BM526_18830	COG2200	EAL domain
BM526_18830	COG2202	Pas domain
BM526_18830	COG2199	diguanylate cyclase activity
BM526_18855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_18865	COG0745	RESPONSE REGULATOR receiver
BM526_18870	COG4999	Histidine kinase
BM526_18870	COG3850	Histidine kinase
BM526_18870	COG2205	protein histidine kinase activity
BM526_18870	COG3437	response regulator, receiver
BM526_18935	COG0210	DNA helicase
BM526_18975	COG0840	transmembrane signaling receptor activity
BM526_19375	COG2337	Toxic component of a toxin-antitoxin (TA) module
BM526_19400	COG0305	Participates in initiation and elongation during chromosome replication
BM526_19535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM526_19535	COG1199	ATP-dependent helicase activity
BM526_19730	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BM526_19745	COG2176	DNA-directed DNA polymerase activity
BM526_19790	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM526_19845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BM526_19860	COG0583	DNA-binding transcription factor activity
BM526_19875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BM526_19880	COG2974	May be involved in recombination
BM526_19885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM526_19910	COG0358	DNA primase activity
BM526_20020	COG2805	Type II/IV secretion system protein
BM526_20060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM526_20145	COG5001	Diguanylate cyclase
BM526_20145	COG3447	MASE1 domain protein
BM526_20145	COG5002	protein histidine kinase activity
BM526_20265	COG0776	regulation of translation