locus-tag	class	description
AV941_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AV941_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AV941_00020	COG0187	DNA topoisomerase II activity
AV941_00040	COG2818	Glycosylase
AV941_00050	COG3078	GTPase activator activity
AV941_00070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV941_00070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV941_00075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AV941_00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AV941_00085	COG0569	domain protein
AV941_00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV941_00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV941_00095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AV941_00110	COG0758	DNA mediated transformation
AV941_00125	COG0009	L-threonylcarbamoyladenylate synthase
AV941_00130	COG0408	coproporphyrinogen oxidase activity
AV941_00135	COG3047	cAMP biosynthetic process
AV941_00150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AV941_00225	COG2234	aminopeptidase activity
AV941_00230	COG0463	Glycosyl transferase, family 2
AV941_00240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AV941_00265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV941_00295	COG3642	lipopolysaccharide core region biosynthetic process
AV941_00300	COG0859	PFAM glycosyl transferase family 9
AV941_00330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_00345	COG3161	chorismate lyase activity
AV941_00350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AV941_00370	COG0210	DNA helicase
AV941_00415	COG1959	2 iron, 2 sulfur cluster binding
AV941_00420	COG0730	response to heat
AV941_00435	COG4771	TonB-dependent receptor
AV941_00450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AV941_00455	COG4988	ABC transporter
AV941_00465	COG1271	oxidase subunit
AV941_00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_00475	COG0425	Belongs to the sulfur carrier protein TusA family
AV941_00485	COG0450	alkyl hydroperoxide reductase
AV941_00495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV941_00525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV941_00570	COG0270	DNA (cytosine-5-)-methyltransferase activity
AV941_00575	COG0556	nucleotide-excision repair
AV941_00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_00590	COG0842	Transport permease protein
AV941_00590	COG1129	ABC transporter
AV941_00595	COG0842	Transport permease protein
AV941_00610	COG1960	acyl-CoA dehydrogenase activity
AV941_00615	COG0583	DNA-binding transcription factor activity
AV941_00625	COG3106	COG3106 Predicted ATPase
AV941_00640	COG2184	nucleotidyltransferase activity
AV941_00645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AV941_00660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AV941_00665	COG0352	thiamine-phosphate diphosphorylase activity
AV941_00675	COG3071	HemY protein
AV941_00680	COG2959	enzyme of heme biosynthesis
AV941_00690	COG0181	hydroxymethylbilane synthase activity
AV941_00705	COG0194	GDP metabolic process
AV941_00715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV941_00725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV941_00730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AV941_00740	COG0678	peroxiredoxin activity
AV941_00755	COG1178	ABC-type Fe3 transport system permease component
AV941_00760	COG3842	ATPase activity
AV941_00765	COG0668	transmembrane transport
AV941_00770	COG2081	HI0933 family
AV941_00790	COG2963	transposase activity
AV941_00825	COG0789	Transcriptional regulator
AV941_00830	COG2963	transposase activity
AV941_00835	COG2801	Transposase and inactivated derivatives
AV941_00850	COG2200	EAL domain
AV941_00855	COG0583	DNA-binding transcription factor activity
AV941_00865	COG2076	Multidrug Resistance protein
AV941_00880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_00895	COG0427	acetyl-CoA hydrolase
AV941_00900	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV941_00915	COG0840	transmembrane signaling receptor activity
AV941_00925	COG3064	Membrane
AV941_00935	COG5002	protein histidine kinase activity
AV941_00935	COG5001	Diguanylate cyclase
AV941_00950	COG0514	ATP-dependent DNA helicase (RecQ)
AV941_00955	COG2239	Acts as a magnesium transporter
AV941_00960	COG2962	Rard protein
AV941_00965	COG0745	RESPONSE REGULATOR receiver
AV941_00965	COG3706	GGDEF domain
AV941_00970	COG0210	DNA helicase
AV941_00980	COG1011	Hydrolase
AV941_00995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AV941_01000	COG0019	diaminopimelate decarboxylase activity
AV941_01030	COG0163	prenyltransferase activity
AV941_01035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV941_01045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AV941_01065	COG1077	Cell shape determining protein MreB Mrl
AV941_01070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AV941_01075	COG2814	Major facilitator Superfamily
AV941_01080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV941_01105	COG1085	galactose-1-phosphate uridylyltransferase
AV941_01110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AV941_01120	COG0629	single-stranded DNA binding
AV941_01135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV941_01140	COG3250	beta-galactosidase activity
AV941_01160	COG1349	DNA-binding transcription factor activity
AV941_01205	COG3267	Type II secretory pathway component ExeA
AV941_01205	COG3409	Peptidoglycan-binding domain 1 protein
AV941_01220	COG1459	type II secretion system
AV941_01265	COG1077	Cell shape determining protein MreB Mrl
AV941_01270	COG1792	Involved in formation and maintenance of cell shape
AV941_01275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AV941_01285	COG1530	ribonuclease E activity
AV941_01295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV941_01300	COG0312	modulator of DNA gyrase
AV941_01305	COG3028	Belongs to the UPF0307 family
AV941_01310	COG0312	modulator of DNA gyrase
AV941_01320	COG0745	RESPONSE REGULATOR receiver
AV941_01325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV941_01325	COG4191	Histidine kinase
AV941_01330	COG0297	glycogen (starch) synthase activity
AV941_01340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AV941_01345	COG0596	Alpha beta hydrolase
AV941_01370	COG5002	protein histidine kinase activity
AV941_01375	COG0745	RESPONSE REGULATOR receiver
AV941_01395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_01485	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AV941_01515	COG0375	protein maturation
AV941_01525	COG0409	Hydrogenase expression formation protein
AV941_01535	COG0309	Hydrogenase expression formation protein (HypE)
AV941_01540	COG0789	Transcriptional regulator
AV941_01545	COG2217	Heavy metal translocating P-type atpase
AV941_01630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV941_01640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV941_01650	COG0463	Glycosyl transferase, family 2
AV941_01655	COG0745	RESPONSE REGULATOR receiver
AV941_01660	COG5002	protein histidine kinase activity
AV941_01675	COG0789	Transcriptional regulator
AV941_01680	COG2217	Heavy metal translocating P-type atpase
AV941_01715	COG0531	amino acid
AV941_01725	COG2132	Multicopper oxidase
AV941_01765	COG2801	Transposase and inactivated derivatives
AV941_01820	COG0546	phosphoglycolate phosphatase activity
AV941_01840	COG1609	Transcriptional regulator
AV941_01845	COG0673	inositol 2-dehydrogenase activity
AV941_01855	COG2211	Major facilitator Superfamily
AV941_01880	COG1454	alcohol dehydrogenase
AV941_01950	COG0089	rRNA binding
AV941_01960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AV941_01970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AV941_01985	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AV941_01990	COG0438	transferase activity, transferring glycosyl groups
AV941_02000	COG1519	Transferase
AV941_02035	COG0788	formyltetrahydrofolate deformylase activity
AV941_02045	COG1643	Atp-dependent helicase
AV941_02050	COG2951	lytic endotransglycosylase activity
AV941_02055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV941_02065	COG2354	Protein conserved in bacteria
AV941_02070	COG4977	sequence-specific DNA binding
AV941_02085	COG0004	ammonium transporteR
AV941_02090	COG0405	Gamma-glutamyltransferase
AV941_02095	COG2837	iron assimilation
AV941_02110	COG0540	Belongs to the ATCase OTCase family
AV941_02135	COG0784	Response regulator, receiver
AV941_02135	COG2205	protein histidine kinase activity
AV941_02135	COG5002	protein histidine kinase activity
AV941_02150	COG3300	MHYT domain
AV941_02150	COG5001	Diguanylate cyclase
AV941_02160	COG1012	belongs to the aldehyde dehydrogenase family
AV941_02170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV941_02185	COG0180	Tryptophanyl-tRNA synthetase
AV941_02190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AV941_02210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AV941_02220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AV941_02255	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AV941_02260	COG0281	malic enzyme
AV941_02270	COG0625	glutathione transferase activity
AV941_02280	COG0753	catalase activity
AV941_02295	COG3300	MHYT domain
AV941_02295	COG5001	Diguanylate cyclase
AV941_02300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV941_02300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AV941_02310	COG0137	argininosuccinate synthase activity
AV941_02330	COG1803	Methylglyoxal synthase
AV941_02340	COG0745	RESPONSE REGULATOR receiver
AV941_02345	COG2205	protein histidine kinase activity
AV941_02350	COG2267	carboxylic ester hydrolase activity
AV941_02355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AV941_02365	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AV941_02375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV941_02380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_02385	COG4942	peptidase
AV941_02390	COG2861	carbohydrate metabolic process
AV941_02415	COG1162	GTPase activity
AV941_02420	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AV941_02455	COG0028	Belongs to the TPP enzyme family
AV941_02475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV941_02480	COG0805	protein transport
AV941_02490	COG0084	hydrolase, TatD family'
AV941_02495	COG2203	Gaf domain
AV941_02495	COG3706	GGDEF domain
AV941_02495	COG4251	negative regulation of phosphorylation
AV941_02495	COG5001	Diguanylate cyclase
AV941_02505	COG0248	Ppx GppA phosphatase
AV941_02510	COG0513	Belongs to the DEAD box helicase family
AV941_02515	COG3118	belongs to the thioredoxin family
AV941_02520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AV941_02530	COG0784	Response regulator, receiver
AV941_02530	COG5002	protein histidine kinase activity
AV941_02535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AV941_02545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AV941_02560	COG0783	Belongs to the Dps family
AV941_02565	COG2133	pyrroloquinoline quinone binding
AV941_02570	COG1506	peptidase
AV941_02570	COG4946	Tricorn protease homolog
AV941_02570	COG0823	Involved in the tonB-independent uptake of proteins
AV941_02580	COG3118	belongs to the thioredoxin family
AV941_02595	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AV941_02605	COG1012	belongs to the aldehyde dehydrogenase family
AV941_02625	COG1757	Na H antiporter
AV941_02640	COG3876	Protein conserved in bacteria
AV941_02645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AV941_02655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AV941_02665	COG0346	lactoylglutathione lyase activity
AV941_02690	COG2824	Alkylphosphonate utilization operon protein PhnA
AV941_02695	COG0454	-acetyltransferase
AV941_02725	COG3093	addiction module antidote protein HigA
AV941_02740	COG2026	Addiction module toxin, RelE StbE family
AV941_02845	COG3547	Transposase (IS116 IS110 IS902 family)
AV941_02900	COG0183	Belongs to the thiolase family
AV941_02905	COG1024	Enoyl-CoA hydratase
AV941_02905	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV941_02915	COG0006	proline dipeptidase activity
AV941_02925	COG0142	geranyltranstransferase activity
AV941_02955	COG4942	peptidase
AV941_02955	COG1388	LysM domain
AV941_02960	COG1238	metal cluster binding
AV941_02970	COG0585	pseudouridine synthase activity
AV941_02975	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AV941_02985	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AV941_02995	COG0840	transmembrane signaling receptor activity
AV941_03030	COG0494	nUDIX hydrolase
AV941_03035	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AV941_03040	COG0730	response to heat
AV941_03045	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AV941_03050	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AV941_03060	COG0745	RESPONSE REGULATOR receiver
AV941_03060	COG3706	GGDEF domain
AV941_03085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AV941_03095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AV941_03105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV941_03105	COG1648	precorrin-2 dehydrogenase activity
AV941_03110	COG0513	Belongs to the DEAD box helicase family
AV941_03125	COG1538	Outer membrane efflux protein
AV941_03130	COG0494	nUDIX hydrolase
AV941_03140	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AV941_03145	COG3150	esterase
AV941_03150	COG0187	DNA topoisomerase II activity
AV941_03160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV941_03185	COG1509	lysine 2,3-aminomutase activity
AV941_03195	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AV941_03210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV941_03225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV941_03240	COG0271	Belongs to the BolA IbaG family
AV941_03255	COG3707	response regulator
AV941_03270	COG0659	secondary active sulfate transmembrane transporter activity
AV941_03275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AV941_03285	COG0243	molybdopterin cofactor binding
AV941_03290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV941_03290	COG1648	precorrin-2 dehydrogenase activity
AV941_03295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV941_03305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AV941_03305	COG1116	anion transmembrane transporter activity
AV941_03315	COG1116	anion transmembrane transporter activity
AV941_03330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV941_03335	COG4206	TonB-dependent receptor
AV941_03345	COG0348	domain, Protein
AV941_03360	COG1960	acyl-CoA dehydrogenase activity
AV941_03365	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_03375	COG4948	Mandelate Racemase Muconate Lactonizing
AV941_03390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_03395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_03415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV941_03420	COG0358	DNA primase activity
AV941_03445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AV941_03450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV941_03465	COG0537	adenosine 5'-monophosphoramidase activity
AV941_03480	COG3135	benzoate transporter
AV941_03485	COG1396	sequence-specific DNA binding
AV941_03490	COG2974	May be involved in recombination
AV941_03495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV941_03495	COG4191	Histidine kinase
AV941_03500	COG0745	RESPONSE REGULATOR receiver
AV941_03505	COG5002	protein histidine kinase activity
AV941_03530	COG0811	peptide transport
AV941_03535	COG0811	peptide transport
AV941_03540	COG0848	biopolymer transport protein
AV941_03545	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AV941_03555	COG3437	response regulator, receiver
AV941_03565	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_03575	COG2133	pyrroloquinoline quinone binding
AV941_03585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV941_03610	COG0527	aspartate kinase activity
AV941_03615	COG0840	transmembrane signaling receptor activity
AV941_03620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV941_03625	COG2967	ApaG domain
AV941_03635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AV941_03640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV941_03645	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AV941_03650	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AV941_03660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV941_03680	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AV941_03695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV941_03700	COG3956	TIGRFAM MazG family protein
AV941_03725	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_03735	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_03745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV941_03755	COG0463	Glycosyl transferase, family 2
AV941_03775	COG0642	Histidine kinase
AV941_03780	COG0745	RESPONSE REGULATOR receiver
AV941_03795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV941_03800	COG0723	plastoquinol--plastocyanin reductase activity
AV941_03805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AV941_03810	COG2857	Cytochrome c1
AV941_03815	COG0625	glutathione transferase activity
AV941_03820	COG2969	positive regulation of protein catabolic process
AV941_03825	COG2239	Acts as a magnesium transporter
AV941_03830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV941_03840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV941_03850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AV941_03855	COG1137	ATPase activity
AV941_03860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AV941_03870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AV941_03885	COG1127	ABC transporter
AV941_03890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV941_03895	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV941_03900	COG2854	intermembrane phospholipid transfer
AV941_03910	COG5007	Belongs to the BolA IbaG family
AV941_03920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV941_03925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV941_03935	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AV941_03975	COG4771	TonB-dependent receptor
AV941_03980	COG0697	spore germination
AV941_03990	COG0784	Response regulator, receiver
AV941_03990	COG2205	protein histidine kinase activity
AV941_04015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV941_04025	COG0126	phosphoglycerate kinase activity
AV941_04030	COG3588	fructose-bisphosphate aldolase
AV941_04040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_04050	COG1538	Outer membrane efflux protein
AV941_04055	COG4946	Tricorn protease homolog
AV941_04055	COG1506	peptidase
AV941_04055	COG0823	Involved in the tonB-independent uptake of proteins
AV941_04060	COG0248	Ppx GppA phosphatase
AV941_04065	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AV941_04075	COG0573	inorganic phosphate transmembrane transporter activity
AV941_04085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV941_04095	COG0306	phosphate transporter
AV941_04105	COG0583	DNA-binding transcription factor activity
AV941_04115	COG1272	protein, Hemolysin III
AV941_04120	COG1846	Transcriptional regulator
AV941_04125	COG1764	response to oxidative stress
AV941_04140	COG1739	Uncharacterized protein family UPF0029
AV941_04160	COG0420	3'-5' exonuclease activity
AV941_04165	COG0419	ATPase involved in DNA repair
AV941_04175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AV941_04200	COG2986	histidine ammonia-lyase
AV941_04225	COG0488	(ABC) transporter
AV941_04245	COG0668	transmembrane transport
AV941_04315	COG1484	DNA-dependent DNA replication
AV941_04330	COG0582	viral genome integration into host DNA
AV941_04335	COG4372	Transposase
AV941_04380	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AV941_04395	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AV941_04445	COG1346	cytolysis
AV941_04475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV941_04485	COG0513	Belongs to the DEAD box helicase family
AV941_04495	COG3409	Peptidoglycan-binding domain 1 protein
AV941_04495	COG3267	Type II secretory pathway component ExeA
AV941_04510	COG0066	3-isopropylmalate dehydratase activity
AV941_04520	COG0473	3-isopropylmalate dehydrogenase activity
AV941_04525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV941_04545	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AV941_04560	COG4555	ABC transporter
AV941_04565	COG1668	transmembrane transport
AV941_04585	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV941_04590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV941_04595	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV941_04605	COG1138	Cytochrome C-type biogenesis protein
AV941_04610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV941_04625	COG2853	Lipoprotein
AV941_04630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV941_04640	COG3104	oligopeptide transport
AV941_04670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV941_04685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AV941_04690	COG1555	photosystem II stabilization
AV941_04690	COG1596	polysaccharide export
AV941_04695	COG0473	3-isopropylmalate dehydrogenase activity
AV941_04710	COG1611	Belongs to the LOG family
AV941_04715	COG0745	RESPONSE REGULATOR receiver
AV941_04715	COG3706	GGDEF domain
AV941_04720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV941_04720	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV941_04775	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AV941_04780	COG0024	Methionine aminopeptidase
AV941_04785	COG0052	Belongs to the universal ribosomal protein uS2 family
AV941_04795	COG0528	UMP kinase activity
AV941_04805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV941_04810	COG0575	Belongs to the CDS family
AV941_04835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV941_04855	COG0587	DNA-directed DNA polymerase activity
AV941_04860	COG0825	malonyl-CoA metabolic process
AV941_04865	COG0037	tRNA processing
AV941_04885	COG0590	tRNA wobble adenosine to inosine editing
AV941_04895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AV941_04895	COG0047	phosphoribosylformylglycinamidine synthase activity
AV941_04900	COG2840	Smr protein MutS2
AV941_04930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_04935	COG2197	response regulator
AV941_04970	COG0835	chemotaxis
AV941_04970	COG0784	Response regulator, receiver
AV941_04975	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AV941_04980	COG1815	bacterial-type flagellum-dependent cell motility
AV941_04985	COG1558	bacterial-type flagellum-dependent cell motility
AV941_04990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AV941_04995	COG1749	Flagellar hook protein flgE
AV941_05000	COG4787	bacterial-type flagellum-dependent cell motility
AV941_05005	COG4786	Flagellar basal body rod
AV941_05020	COG3951	Flagellar rod assembly protein muramidase FlgJ
AV941_05020	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV941_05025	COG1256	bacterial-type flagellum assembly
AV941_05040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV941_05045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV941_05060	COG1516	flagellar protein fliS
AV941_05075	COG1086	Polysaccharide biosynthesis protein
AV941_05080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AV941_05090	COG2089	acid synthase
AV941_05105	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_05110	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_05155	COG1660	Displays ATPase and GTPase activities
AV941_05160	COG1216	Glycosyl transferase, family 2
AV941_05175	COG1083	cytidylyl-transferase
AV941_05185	COG2204	response regulator
AV941_05190	COG3852	Histidine kinase
AV941_05195	COG2204	response regulator
AV941_05200	COG1677	Flagellar hook-basal body complex protein FliE
AV941_05205	COG1766	The M ring may be actively involved in energy transduction
AV941_05210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV941_05260	COG1987	bacterial-type flagellum assembly
AV941_05275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV941_05285	COG0455	bacterial-type flagellum organization
AV941_05300	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AV941_05305	COG2198	Histidine kinase
AV941_05305	COG0643	Histidine kinase
AV941_05315	COG1192	Involved in chromosome partitioning
AV941_05325	COG0835	chemotaxis
AV941_05340	COG1410	methionine synthase
AV941_05340	COG0646	methionine synthase
AV941_05345	COG0646	methionine synthase
AV941_05345	COG1410	methionine synthase
AV941_05355	COG3123	guanosine phosphorylase activity
AV941_05360	COG0583	DNA-binding transcription factor activity
AV941_05365	COG0583	DNA-binding transcription factor activity
AV941_05375	COG0659	secondary active sulfate transmembrane transporter activity
AV941_05390	COG3590	peptidase
AV941_05400	COG2137	regulation of response to DNA damage stimulus
AV941_05405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AV941_05435	COG0511	ligase activity, forming carbon-carbon bonds
AV941_05435	COG5016	pyruvate
AV941_05440	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AV941_05445	COG4172	Belongs to the ABC transporter superfamily
AV941_05455	COG4171	peptide transport system, permease
AV941_05460	COG4168	peptide transport system, permease
AV941_05465	COG0747	negative chemotaxis
AV941_05470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AV941_05475	COG1842	Phage shock protein A
AV941_05505	COG0625	glutathione transferase activity
AV941_05510	COG1522	sequence-specific DNA binding
AV941_05575	COG0811	peptide transport
AV941_05580	COG0811	peptide transport
AV941_05585	COG0848	biopolymer transport protein
AV941_05600	COG1444	tRNA N-acetyltransferase activity
AV941_05640	COG0456	acetyltransferase
AV941_05655	COG0583	DNA-binding transcription factor activity
AV941_05660	COG2814	Major facilitator Superfamily
AV941_05665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV941_05670	COG0656	L-ascorbic acid biosynthetic process
AV941_05690	COG1846	Transcriptional regulator
AV941_05700	COG3620	sequence-specific DNA binding
AV941_05705	COG3550	peptidyl-serine autophosphorylation
AV941_05740	COG0668	transmembrane transport
AV941_05750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AV941_05770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AV941_05860	COG0789	Transcriptional regulator
AV941_05875	COG0789	Transcriptional regulator
AV941_05880	COG0640	Transcriptional regulator
AV941_05890	COG1230	cation diffusion facilitator family transporter
AV941_05915	COG1538	Outer membrane efflux protein
AV941_05930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_05945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV941_05960	COG0681	Belongs to the peptidase S26 family
AV941_05980	COG1074	ATP-dependent DNA helicase activity
AV941_05990	COG1404	Belongs to the peptidase S8 family
AV941_05995	COG0464	growth
AV941_06015	COG0629	single-stranded DNA binding
AV941_06030	COG0714	Associated with various cellular activities
AV941_06055	COG2003	Belongs to the UPF0758 family
AV941_06075	COG0583	DNA-binding transcription factor activity
AV941_06165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV941_06175	COG3706	GGDEF domain
AV941_06215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AV941_06220	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AV941_06225	COG0564	pseudouridine synthase activity
AV941_06235	COG0612	Peptidase, M16
AV941_06240	COG2918	glutathione biosynthetic process
AV941_06260	COG2840	Smr protein MutS2
AV941_06265	COG2890	protein-(glutamine-N5) methyltransferase activity
AV941_06280	COG2719	SpoVR family
AV941_06285	COG2718	Belongs to the UPF0229 family
AV941_06290	COG2766	serine protein kinase
AV941_06300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AV941_06305	COG4771	TonB-dependent receptor
AV941_06330	COG0450	alkyl hydroperoxide reductase
AV941_06335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV941_06340	COG2885	chlorophyll binding
AV941_06345	COG0584	glycerophosphoryl diester phosphodiesterase
AV941_06350	COG0346	lactoylglutathione lyase activity
AV941_06355	COG1278	Cold shock
AV941_06370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AV941_06375	COG4660	Part of a membrane complex involved in electron transport
AV941_06380	COG4659	FMN binding
AV941_06385	COG4658	electron transport chain
AV941_06390	COG4656	Part of a membrane complex involved in electron transport
AV941_06395	COG2878	Part of a membrane complex involved in electron transport
AV941_06415	COG0534	Mate efflux family protein
AV941_06420	COG0556	nucleotide-excision repair
AV941_06435	COG0602	queuosine metabolic process
AV941_06445	COG0367	asparagine synthase
AV941_06470	COG3273	potassium ion transport
AV941_06470	COG0471	metal ion transport
AV941_06485	COG0529	Catalyzes the synthesis of activated sulfate
AV941_06490	COG0175	sulfate reduction
AV941_06495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV941_06500	COG3706	GGDEF domain
AV941_06525	COG2304	oxidoreductase activity
AV941_06545	COG0714	Associated with various cellular activities
AV941_06555	COG1024	Enoyl-CoA hydratase
AV941_06555	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV941_06570	COG1025	Belongs to the peptidase M16 family
AV941_06575	COG2062	phosphohistidine phosphatase, SixA
AV941_06585	COG4536	flavin adenine dinucleotide binding
AV941_06590	COG4137	Cytochrome C assembly protein
AV941_06595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AV941_06640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_06645	COG1132	(ABC) transporter
AV941_06660	COG0228	four-way junction DNA binding
AV941_06665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AV941_06670	COG0336	Belongs to the RNA methyltransferase TrmD family
AV941_06675	COG0335	large ribosomal subunit rRNA binding
AV941_06680	COG2860	membrane
AV941_06690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AV941_06695	COG0287	Prephenate dehydrogenase
AV941_06695	COG1605	Chorismate mutase
AV941_06700	COG1605	Chorismate mutase
AV941_06700	COG0077	Prephenate dehydratase
AV941_06710	COG0023	Translation Initiation Factor
AV941_06740	COG2205	protein histidine kinase activity
AV941_06750	COG2204	response regulator
AV941_06770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AV941_06775	COG0494	nUDIX hydrolase
AV941_06780	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AV941_06790	COG2255	four-way junction helicase activity
AV941_06795	COG0824	Thioesterase
AV941_06800	COG0811	peptide transport
AV941_06815	COG0823	Involved in the tonB-independent uptake of proteins
AV941_06820	COG2885	chlorophyll binding
AV941_06825	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AV941_06850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AV941_06870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AV941_06885	COG4667	esterase of the alpha-beta hydrolase superfamily
AV941_06890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AV941_06900	COG2205	protein histidine kinase activity
AV941_06900	COG0784	Response regulator, receiver
AV941_06920	COG3038	cytochrome b561
AV941_06940	COG0583	DNA-binding transcription factor activity
AV941_06945	COG1451	nucleotide metabolic process
AV941_06955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_06965	COG1309	transcriptional regulator
AV941_06970	COG4774	siderophore transport
AV941_06990	COG3706	GGDEF domain
AV941_07000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV941_07000	COG3008	intermembrane lipid transfer
AV941_07005	COG2995	paraquat-inducible protein a
AV941_07020	COG0017	Asparaginyl-tRNA synthetase
AV941_07035	COG0189	ligase activity
AV941_07065	COG0156	8-amino-7-oxononanoate synthase activity
AV941_07070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV941_07080	COG3340	Belongs to the peptidase S51 family
AV941_07085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AV941_07090	COG4139	cobalamin transport
AV941_07095	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AV941_07100	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AV941_07115	COG5265	(ABC) transporter
AV941_07120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AV941_07130	COG0745	RESPONSE REGULATOR receiver
AV941_07165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV941_07195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV941_07210	COG2755	lipolytic protein G-D-S-L family
AV941_07215	COG4181	ATPase activity
AV941_07220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AV941_07225	COG1090	epimerase
AV941_07230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV941_07235	COG0628	permease
AV941_07245	COG0745	RESPONSE REGULATOR receiver
AV941_07260	COG2350	Protein conserved in bacteria
AV941_07265	COG0159	tryptophan synthase activity
AV941_07275	COG0134	indole-3-glycerol-phosphate synthase activity
AV941_07275	COG0135	phosphoribosylanthranilate isomerase activity
AV941_07280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV941_07290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AV941_07295	COG0613	PHP domain protein
AV941_07300	COG0009	L-threonylcarbamoyladenylate synthase
AV941_07305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AV941_07310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AV941_07320	COG0656	L-ascorbic acid biosynthetic process
AV941_07325	COG0110	maltose O-acetyltransferase activity
AV941_07335	COG2733	membrane
AV941_07355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_07360	COG0500	methyltransferase
AV941_07365	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV941_07370	COG0497	DNA recombination
AV941_07375	COG0783	Belongs to the Dps family
AV941_07385	COG1454	alcohol dehydrogenase
AV941_07390	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_07400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV941_07405	COG2610	gluconate transmembrane transporter activity
AV941_07410	COG4771	TonB-dependent receptor
AV941_07420	COG0784	Response regulator, receiver
AV941_07420	COG2205	protein histidine kinase activity
AV941_07420	COG2198	Histidine kinase
AV941_07425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AV941_07435	COG0484	heat shock protein binding
AV941_07440	COG3909	cytochrome
AV941_07445	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV941_07460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AV941_07465	COG0505	Belongs to the CarA family
AV941_07470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AV941_07475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV941_07495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV941_07500	COG0280	phosphate acetyltransferase
AV941_07500	COG0857	belongs to the CobB CobQ family
AV941_07515	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AV941_07520	COG4535	Mg2 and Co2 transporter CorC
AV941_07530	COG1702	phosphate starvation-inducible protein PhoH
AV941_07540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV941_07570	COG1607	acyl-coa hydrolase
AV941_07575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV941_07585	COG1115	amino acid carrier protein
AV941_07630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV941_07635	COG0012	GTP binding
AV941_07650	COG1064	alcohol dehydrogenase
AV941_07665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AV941_07675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AV941_07680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AV941_07685	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AV941_07695	COG2890	protein-(glutamine-N5) methyltransferase activity
AV941_07700	COG3437	response regulator, receiver
AV941_07700	COG0784	Response regulator, receiver
AV941_07705	COG3094	Invasion gene expression up-regulator, SirB
AV941_07720	COG0583	DNA-binding transcription factor activity
AV941_07730	COG2363	Small membrane protein
AV941_07750	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AV941_07755	COG0515	serine threonine protein kinase
AV941_07760	COG2116	formate transmembrane transporter activity
AV941_07775	COG0714	Associated with various cellular activities
AV941_07780	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AV941_07785	COG0033	Phosphoglucomutase
AV941_07790	COG0058	SHG alpha-glucan phosphorylase activity
AV941_07800	COG2988	succinylglutamate desuccinylase activity
AV941_07835	COG1393	Belongs to the ArsC family
AV941_07860	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AV941_07890	COG3300	MHYT domain
AV941_07890	COG5001	Diguanylate cyclase
AV941_07915	COG2249	NAD(P)H dehydrogenase (quinone) activity
AV941_07935	COG1733	regulation of RNA biosynthetic process
AV941_07940	COG5001	Diguanylate cyclase
AV941_07940	COG5002	protein histidine kinase activity
AV941_07940	COG3447	MASE1 domain protein
AV941_07950	COG0402	S-adenosylhomocysteine deaminase activity
AV941_07955	COG2351	hydroxyisourate hydrolase activity
AV941_07970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV941_07985	COG1309	transcriptional regulator
AV941_08000	COG2252	PERMEase
AV941_08005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV941_08020	COG2203	Gaf domain
AV941_08020	COG3706	GGDEF domain
AV941_08020	COG4251	negative regulation of phosphorylation
AV941_08020	COG5001	Diguanylate cyclase
AV941_08025	COG5001	Diguanylate cyclase
AV941_08025	COG4251	negative regulation of phosphorylation
AV941_08025	COG3706	GGDEF domain
AV941_08025	COG2203	Gaf domain
AV941_08030	COG2205	protein histidine kinase activity
AV941_08030	COG0784	Response regulator, receiver
AV941_08045	COG2233	PERMEase
AV941_08060	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV941_08065	COG0730	response to heat
AV941_08105	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_08120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AV941_08135	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AV941_08135	COG0662	Cupin 2, conserved barrel domain protein
AV941_08140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AV941_08150	COG1596	polysaccharide export
AV941_08155	COG0489	protein tyrosine kinase activity
AV941_08160	COG4464	protein tyrosine phosphatase activity
AV941_08215	COG1216	Glycosyl transferase, family 2
AV941_08230	COG1215	transferase activity, transferring glycosyl groups
AV941_08235	COG0438	transferase activity, transferring glycosyl groups
AV941_08245	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AV941_08265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV941_08265	COG0072	phenylalanine-tRNA ligase activity
AV941_08280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AV941_08290	COG1472	Belongs to the glycosyl hydrolase 3 family
AV941_08295	COG2096	Adenosyltransferase
AV941_08305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AV941_08315	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV941_08340	COG0708	Exodeoxyribonuclease III
AV941_08375	COG2814	Major facilitator Superfamily
AV941_08415	COG1024	Enoyl-CoA hydratase
AV941_08420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AV941_08425	COG1960	acyl-CoA dehydrogenase activity
AV941_08430	COG0789	Transcriptional regulator
AV941_08435	COG0183	Belongs to the thiolase family
AV941_08450	COG3706	GGDEF domain
AV941_08460	COG2925	Exonuclease
AV941_08465	COG0582	viral genome integration into host DNA
AV941_08505	COG0531	amino acid
AV941_08505	COG1674	ftsk spoiiie
AV941_08545	COG2197	response regulator
AV941_08560	COG3617	BRO family, N-terminal domain
AV941_08630	COG0305	Participates in initiation and elongation during chromosome replication
AV941_08720	COG3728	DNA packaging
AV941_08720	COG5484	DNA packaging
AV941_08865	COG1643	Atp-dependent helicase
AV941_08885	COG3321	synthase
AV941_08885	COG0604	alcohol dehydrogenase
AV941_08890	COG0328	RNA-DNA hybrid ribonuclease activity
AV941_08895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV941_08925	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV941_08935	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV941_08950	COG3724	N-succinylarginine dihydrolase activity
AV941_08960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AV941_08975	COG0746	molybdenum cofactor guanylyltransferase activity
AV941_08980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AV941_08985	COG0243	molybdopterin cofactor binding
AV941_08990	COG2153	protein acetylation
AV941_09005	COG1530	ribonuclease E activity
AV941_09020	COG0424	maF-like protein
AV941_09025	COG1399	metal-binding, possibly nucleic acid-binding protein
AV941_09035	COG0416	fatty acid biosynthetic process
AV941_09040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV941_09045	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AV941_09055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV941_09060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV941_09070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AV941_09085	COG0084	hydrolase, TatD family'
AV941_09095	COG0702	epimerase
AV941_09100	COG3706	GGDEF domain
AV941_09100	COG0745	RESPONSE REGULATOR receiver
AV941_09120	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_09125	COG0596	Alpha beta hydrolase
AV941_09135	COG0183	Belongs to the thiolase family
AV941_09140	COG1960	acyl-CoA dehydrogenase activity
AV941_09160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV941_09170	COG0246	Mannitol dehydrogenase
AV941_09190	COG0668	transmembrane transport
AV941_09195	COG4771	TonB-dependent receptor
AV941_09220	COG3437	response regulator, receiver
AV941_09230	COG0195	Participates in both transcription termination and antitermination
AV941_09245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AV941_09260	COG1187	pseudouridine synthase activity
AV941_09270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV941_09270	COG3153	acetyltransferase
AV941_09300	COG0450	alkyl hydroperoxide reductase
AV941_09345	COG1032	radical SAM domain protein
AV941_09360	COG4771	TonB-dependent receptor
AV941_09365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_09375	COG4134	Bacterial extracellular solute-binding protein
AV941_09385	COG4136	ATPase activity
AV941_09390	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AV941_09415	COG5001	Diguanylate cyclase
AV941_09415	COG4251	negative regulation of phosphorylation
AV941_09415	COG3706	GGDEF domain
AV941_09415	COG2203	Gaf domain
AV941_09495	COG1902	pentaerythritol trinitrate reductase activity
AV941_09505	COG2867	negative regulation of translational initiation
AV941_09510	COG2914	Belongs to the UPF0125 (RnfH) family
AV941_09520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV941_09525	COG4771	TonB-dependent receptor
AV941_09530	COG0457	Tetratricopeptide repeat
AV941_09545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AV941_09545	COG0574	Belongs to the PEP-utilizing enzyme family
AV941_09580	COG2850	peptidyl-arginine hydroxylation
AV941_09590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AV941_09595	COG2915	High frequency lysogenization protein hflD homolog
AV941_09600	COG0482	sulfurtransferase activity
AV941_09605	COG1187	pseudouridine synthase activity
AV941_09615	COG1278	Cold shock
AV941_09620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AV941_09625	COG0542	response to heat
AV941_09630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV941_09635	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AV941_09640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AV941_09645	COG0492	ferredoxin-NADP+ reductase activity
AV941_09650	COG3092	negative regulation of chromosome organization
AV941_09655	COG3091	SprT-like family
AV941_09660	COG0616	signal peptide processing
AV941_09675	COG0778	Nitroreductase
AV941_09685	COG0252	asparaginase activity
AV941_09690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AV941_09695	COG0321	lipoyl(octanoyl) transferase activity
AV941_09700	COG2921	Belongs to the UPF0250 family
AV941_09705	COG1686	Belongs to the peptidase S11 family
AV941_09710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV941_09715	COG0772	Belongs to the SEDS family
AV941_09720	COG0768	penicillin binding
AV941_09725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AV941_09730	COG0799	negative regulation of ribosome biogenesis
AV941_09740	COG1466	dna polymerase III delta subunit
AV941_09745	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AV941_09750	COG0495	leucyl-tRNA aminoacylation
AV941_09765	COG1067	ATP-dependent peptidase activity
AV941_09770	COG0596	Alpha beta hydrolase
AV941_09775	COG3706	GGDEF domain
AV941_09785	COG1534	Rna-binding protein
AV941_09790	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AV941_09795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV941_09800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AV941_09805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV941_09810	COG0149	triose-phosphate isomerase activity
AV941_09815	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV941_09825	COG5001	Diguanylate cyclase
AV941_09825	COG3300	MHYT domain
AV941_09840	COG1597	lipid kinase activity
AV941_09840	COG1803	Methylglyoxal synthase
AV941_09850	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_09855	COG0561	phosphatase activity
AV941_09870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV941_09895	COG1185	polyribonucleotide nucleotidyltransferase activity
AV941_09920	COG1819	glycosyl
AV941_10035	COG4372	Transposase
AV941_10065	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AV941_10070	COG1196	nuclear chromosome segregation
AV941_10080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AV941_10095	COG1132	(ABC) transporter
AV941_10100	COG1663	tetraacyldisaccharide 4'-kinase activity
AV941_10135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AV941_10140	COG0435	Glutathione S-transferase
AV941_10145	COG1741	Belongs to the pirin family
AV941_10150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV941_10160	COG0372	Belongs to the citrate synthase family
AV941_10165	COG2009	succinate dehydrogenase
AV941_10170	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AV941_10175	COG1053	succinate dehydrogenase
AV941_10180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AV941_10185	COG0567	Dehydrogenase, E1 component
AV941_10190	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV941_10225	COG4667	esterase of the alpha-beta hydrolase superfamily
AV941_10245	COG0366	Alpha amylase catalytic
AV941_10270	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_10275	COG2267	carboxylic ester hydrolase activity
AV941_10285	COG0616	signal peptide processing
AV941_10305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV941_10310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV941_10315	COG0386	Belongs to the glutathione peroxidase family
AV941_10320	COG2084	Dehydrogenase
AV941_10330	COG1960	acyl-CoA dehydrogenase activity
AV941_10335	COG1024	Enoyl-CoA hydratase
AV941_10340	COG2226	methyltransferase
AV941_10345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV941_10350	COG3083	sulfuric ester hydrolase activity
AV941_10355	COG3082	Protein of unknown function (DUF1414)
AV941_10360	COG3081	Nucleoid-associated protein
AV941_10390	COG3275	phosphorelay sensor kinase activity
AV941_10395	COG3279	Response regulator of the LytR AlgR family
AV941_10400	COG0205	6-phosphofructokinase activity
AV941_10415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_10430	COG2205	protein histidine kinase activity
AV941_10430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV941_10450	COG0513	Belongs to the DEAD box helicase family
AV941_10460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AV941_10465	COG0583	DNA-binding transcription factor activity
AV941_10485	COG1760	l-serine dehydratase
AV941_10510	COG1322	Protein conserved in bacteria
AV941_10515	COG1404	Belongs to the peptidase S8 family
AV941_10520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AV941_10525	COG0022	dehydrogenase e1 component
AV941_10535	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AV941_10540	COG0515	serine threonine protein kinase
AV941_10545	COG1946	Acyl-CoA thioesterase
AV941_10555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV941_10565	COG1956	GAF domain-containing protein
AV941_10580	COG0793	Belongs to the peptidase S41A family
AV941_10585	COG0733	neurotransmitter:sodium symporter activity
AV941_10595	COG0308	aminopeptidase N
AV941_10625	COG2902	Dehydrogenase
AV941_10630	COG0167	dihydroorotate dehydrogenase activity
AV941_10655	COG3130	regulation of translation
AV941_10660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV941_10670	COG0415	Belongs to the DNA photolyase family
AV941_10675	COG0415	Belongs to the DNA photolyase family
AV941_10680	COG0415	Belongs to the DNA photolyase family
AV941_10685	COG3046	protein related to deoxyribodipyrimidine photolyase
AV941_10695	COG4974	Belongs to the 'phage' integrase family
AV941_10705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV941_10710	COG0589	response to stress
AV941_10720	COG0069	glutamate synthase activity
AV941_10735	COG2193	ferroxidase activity
AV941_10745	COG3278	Belongs to the heme-copper respiratory oxidase family
AV941_10760	COG2010	Cytochrome c
AV941_10785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV941_10790	COG0589	response to stress
AV941_10795	COG0037	tRNA processing
AV941_10800	COG1752	Esterase of the alpha-beta hydrolase superfamily
AV941_10820	COG1280	lysine exporter protein (LysE YggA)
AV941_10825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AV941_10830	COG2897	thiosulfate sulfurtransferase activity
AV941_10835	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AV941_10865	COG0322	excinuclease ABC activity
AV941_10870	COG2197	response regulator
AV941_10875	COG0436	Aminotransferase
AV941_10895	COG2259	Doxx family
AV941_10900	COG0583	DNA-binding transcription factor activity
AV941_10915	COG0670	Belongs to the BI1 family
AV941_10920	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AV941_10935	COG2920	part of a sulfur-relay system
AV941_10965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AV941_10975	COG1674	ftsk spoiiie
AV941_10975	COG0531	amino acid
AV941_10985	COG0686	Belongs to the AlaDH PNT family
AV941_10990	COG0284	orotidine-5'-phosphate decarboxylase activity
AV941_10995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AV941_11010	COG0776	regulation of translation
AV941_11015	COG0539	negative regulation of cytoplasmic translation
AV941_11020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AV941_11025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AV941_11030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AV941_11040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV941_11045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV941_11050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV941_11055	COG0633	Ferredoxin
AV941_11085	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AV941_11090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV941_11100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AV941_11110	COG4783	chaperone-mediated protein folding
AV941_11120	COG1393	Belongs to the ArsC family
AV941_11135	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AV941_11150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AV941_11160	COG1960	acyl-CoA dehydrogenase activity
AV941_11185	COG0572	uridine kinase
AV941_11190	COG3769	mannosylglycerate metabolic process
AV941_11195	COG1215	transferase activity, transferring glycosyl groups
AV941_11200	COG0366	Alpha amylase catalytic
AV941_11210	COG0303	'Molybdopterin
AV941_11215	COG0534	Mate efflux family protein
AV941_11230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV941_11235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV941_11265	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AV941_11310	COG0405	Gamma-glutamyltransferase
AV941_11315	COG1024	Enoyl-CoA hydratase
AV941_11360	COG1448	Aminotransferase
AV941_11370	COG1671	Belongs to the UPF0178 family
AV941_11375	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_11380	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_11385	COG1960	acyl-CoA dehydrogenase activity
AV941_11390	COG2207	Transcriptional regulator
AV941_11390	COG0662	Cupin 2, conserved barrel domain protein
AV941_11405	COG1505	serine-type exopeptidase activity
AV941_11415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_11445	COG0596	Alpha beta hydrolase
AV941_11455	COG0716	FMN binding
AV941_11465	COG0735	belongs to the Fur family
AV941_11475	COG1984	allophanate hydrolase subunit 2
AV941_11480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AV941_11485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AV941_11490	COG2996	Protein conserved in bacteria
AV941_11495	COG1765	OsmC-like protein
AV941_11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_11510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV941_11525	COG0436	Aminotransferase
AV941_11535	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV941_11545	COG2010	Cytochrome c
AV941_11545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV941_11550	COG2080	2 iron, 2 sulfur cluster binding
AV941_11575	COG1073	alpha beta
AV941_11580	COG2207	Transcriptional regulator
AV941_11595	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AV941_11620	COG3012	SEC-C Motif Domain Protein
AV941_11625	COG0604	alcohol dehydrogenase
AV941_11635	COG1960	acyl-CoA dehydrogenase activity
AV941_11645	COG4771	TonB-dependent receptor
AV941_11665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV941_11670	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AV941_11690	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AV941_11695	COG0315	cyclic pyranopterin monophosphate synthase activity
AV941_11700	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV941_11715	COG2161	toxin-antitoxin pair type II binding
AV941_11720	COG4115	mRNA cleavage
AV941_11735	COG0436	Aminotransferase
AV941_11740	COG3268	Saccharopine dehydrogenase
AV941_11745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV941_11760	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AV941_11765	COG4206	TonB-dependent receptor
AV941_11775	COG5006	permease, DMT superfamily
AV941_11790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AV941_11795	COG1074	ATP-dependent DNA helicase activity
AV941_11800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AV941_11815	COG1022	Amp-dependent synthetase and ligase
AV941_11820	COG5001	Diguanylate cyclase
AV941_11820	COG3706	GGDEF domain
AV941_11820	COG2203	Gaf domain
AV941_11820	COG4251	negative regulation of phosphorylation
AV941_11840	COG0583	DNA-binding transcription factor activity
AV941_11860	COG0640	Transcriptional regulator
AV941_11880	COG2204	response regulator
AV941_11890	COG4251	negative regulation of phosphorylation
AV941_11895	COG0784	Response regulator, receiver
AV941_11900	COG0784	Response regulator, receiver
AV941_11900	COG2205	protein histidine kinase activity
AV941_11925	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV941_11945	COG3139	Protein of unknown function (DUF1315)
AV941_11960	COG1115	amino acid carrier protein
AV941_11965	COG2866	Carboxypeptidase
AV941_11985	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AV941_11995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV941_12000	COG1640	4-alpha-glucanotransferase
AV941_12005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AV941_12010	COG0676	glucose-6-phosphate 1-epimerase activity
AV941_12015	COG0800	Aldolase
AV941_12025	COG0129	dihydroxy-acid dehydratase activity
AV941_12040	COG1737	Transcriptional regulator
AV941_12045	COG0469	pyruvate kinase activity
AV941_12060	COG1960	acyl-CoA dehydrogenase activity
AV941_12080	COG0471	metal ion transport
AV941_12080	COG0490	domain, Protein
AV941_12095	COG1737	Transcriptional regulator
AV941_12100	COG0469	pyruvate kinase activity
AV941_12105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV941_12125	COG2823	Periplasmic or secreted lipoprotein
AV941_12155	COG3665	Urea carboxylase-associated protein
AV941_12185	COG2356	endonuclease I
AV941_12190	COG0840	transmembrane signaling receptor activity
AV941_12205	COG0583	DNA-binding transcription factor activity
AV941_12210	COG1979	alcohol dehydrogenase
AV941_12215	COG5001	Diguanylate cyclase
AV941_12225	COG3437	response regulator, receiver
AV941_12225	COG0784	Response regulator, receiver
AV941_12230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV941_12230	COG4191	Histidine kinase
AV941_12310	COG0471	metal ion transport
AV941_12320	COG0489	protein tyrosine kinase activity
AV941_12325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV941_12325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV941_12330	COG0668	transmembrane transport
AV941_12335	COG2226	methyltransferase
AV941_12340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_12345	COG1388	LysM domain
AV941_12345	COG0741	lytic transglycosylase activity
AV941_12370	COG0215	cysteine-tRNA ligase activity
AV941_12375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV941_12380	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV941_12390	COG2268	Band 7 protein
AV941_12405	COG1733	regulation of RNA biosynthetic process
AV941_12410	COG0604	alcohol dehydrogenase
AV941_12415	COG0753	catalase activity
AV941_12420	COG0604	alcohol dehydrogenase
AV941_12425	COG0583	DNA-binding transcription factor activity
AV941_12460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AV941_12465	COG1286	toxin biosynthetic process
AV941_12470	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AV941_12475	COG0285	dihydrofolate synthase activity
AV941_12495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AV941_12500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV941_12520	COG3609	addiction module antidote protein, CC2985 family
AV941_12530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV941_12535	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_12545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV941_12545	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AV941_12580	COG0789	Transcriptional regulator
AV941_12585	COG0604	alcohol dehydrogenase
AV941_12610	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_12615	COG1119	ATPase activity
AV941_12620	COG2031	fatty acid transporter
AV941_12625	COG0784	Response regulator, receiver
AV941_12625	COG2205	protein histidine kinase activity
AV941_12625	COG5002	protein histidine kinase activity
AV941_12635	COG0612	Peptidase, M16
AV941_12650	COG3101	peptidyl-lysine hydroxylation
AV941_12680	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV941_12680	COG1902	pentaerythritol trinitrate reductase activity
AV941_12705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV941_12715	COG4399	Belongs to the UPF0754 family
AV941_12740	COG1770	oligopeptidase
AV941_12745	COG2186	Transcriptional regulator
AV941_12755	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AV941_12760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV941_12770	COG2983	Belongs to the UPF0260 family
AV941_12775	COG0179	Fumarylacetoacetate (FAA) hydrolase
AV941_12790	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AV941_12795	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_12800	COG2267	carboxylic ester hydrolase activity
AV941_12815	COG1214	PFAM Peptidase M22, glycoprotease
AV941_12820	COG1199	ATP-dependent helicase activity
AV941_12870	COG4771	TonB-dependent receptor
AV941_12880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AV941_12885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AV941_12890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV941_12895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV941_12895	COG0131	Imidazoleglycerol-phosphate dehydratase
AV941_12900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AV941_12915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AV941_12915	COG0140	phosphoribosyl-ATP diphosphatase activity
AV941_12930	COG2116	formate transmembrane transporter activity
AV941_12935	COG0612	Peptidase, M16
AV941_12965	COG0326	Molecular chaperone. Has ATPase activity
AV941_12970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AV941_12990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV941_12995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AV941_13005	COG3220	belongs to the UPF0276 family
AV941_13015	COG1136	(ABC) transporter
AV941_13015	COG0577	efflux transmembrane transporter activity
AV941_13025	COG4251	negative regulation of phosphorylation
AV941_13025	COG5001	Diguanylate cyclase
AV941_13025	COG2203	Gaf domain
AV941_13025	COG3706	GGDEF domain
AV941_13045	COG1183	phosphatidylcholine synthase activity
AV941_13065	COG0277	FAD linked oxidase domain protein
AV941_13070	COG0542	response to heat
AV941_13080	COG0564	pseudouridine synthase activity
AV941_13095	COG1595	DNA-templated transcription, initiation
AV941_13110	COG4221	oxidoreductase activity
AV941_13125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AV941_13135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AV941_13145	COG0142	geranyltranstransferase activity
AV941_13155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AV941_13160	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AV941_13170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AV941_13185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV941_13185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV941_13205	COG0488	(ABC) transporter
AV941_13215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AV941_13225	COG0560	Phosphoserine phosphatase
AV941_13235	COG0084	hydrolase, TatD family'
AV941_13250	COG0571	ribonuclease III activity
AV941_13255	COG0681	Belongs to the peptidase S26 family
AV941_13280	COG1595	DNA-templated transcription, initiation
AV941_13285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AV941_13300	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AV941_13380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AV941_13385	COG1047	Peptidyl-prolyl cis-trans
AV941_13395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AV941_13400	COG0196	riboflavin kinase activity
AV941_13405	COG0728	peptidoglycan biosynthetic process
AV941_13410	COG0268	Binds directly to 16S ribosomal RNA
AV941_13430	COG0385	Bile acid
AV941_13455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV941_13460	COG0776	regulation of translation
AV941_13470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV941_13475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AV941_13480	COG0740	serine-type endopeptidase activity
AV941_13485	COG0544	peptidyl-prolyl cis-trans isomerase activity
AV941_13530	COG1720	tRNA m6t6A37 methyltransferase activity
AV941_13540	COG1234	tRNA 3'-trailer cleavage
AV941_13550	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV941_13565	COG0516	GMP reductase activity
AV941_13565	COG0517	IMP dehydrogenase activity
AV941_13570	COG1570	exodeoxyribonuclease VII activity
AV941_13590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV941_13595	COG2976	Protein conserved in bacteria
AV941_13620	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AV941_13630	COG2166	iron-sulfur cluster assembly
AV941_13645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AV941_13650	COG0719	Fe-S assembly protein
AV941_13655	COG0396	ATPase activity
AV941_13660	COG0719	Fe-S assembly protein
AV941_13665	COG1104	cysteine desulfurase activity
AV941_13675	COG2072	flavoprotein involved in K transport
AV941_13680	COG1045	serine acetyltransferase
AV941_13685	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AV941_13690	COG0483	inositol monophosphate 1-phosphatase activity
AV941_13705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV941_13710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV941_13715	COG1862	Preprotein translocase
AV941_13720	COG0343	queuine tRNA-ribosyltransferase activity
AV941_13740	COG1842	Phage shock protein A
AV941_13745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AV941_13765	COG0754	glutathionylspermidine amidase activity
AV941_13795	COG2066	Belongs to the glutaminase family
AV941_13800	COG1785	Belongs to the alkaline phosphatase family
AV941_13855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV941_13875	COG0438	transferase activity, transferring glycosyl groups
AV941_13900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AV941_13905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AV941_13935	COG2755	lipolytic protein G-D-S-L family
AV941_13935	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AV941_13940	COG0367	asparagine synthase
AV941_13945	COG0438	transferase activity, transferring glycosyl groups
AV941_13955	COG2244	polysaccharide biosynthetic process
AV941_13985	COG0367	asparagine synthase
AV941_14020	COG0489	protein tyrosine kinase activity
AV941_14030	COG3409	Peptidoglycan-binding domain 1 protein
AV941_14030	COG3267	Type II secretory pathway component ExeA
AV941_14080	COG1560	Kdo2-lipid A biosynthetic process
AV941_14095	COG1960	acyl-CoA dehydrogenase activity
AV941_14110	COG5001	Diguanylate cyclase
AV941_14110	COG3300	MHYT domain
AV941_14115	COG1435	thymidine kinase activity
AV941_14125	COG1609	Transcriptional regulator
AV941_14130	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AV941_14160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AV941_14165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV941_14170	COG1024	Enoyl-CoA hydratase
AV941_14170	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV941_14185	COG1012	belongs to the aldehyde dehydrogenase family
AV941_14205	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AV941_14230	COG1960	acyl-CoA dehydrogenase activity
AV941_14260	COG0745	RESPONSE REGULATOR receiver
AV941_14265	COG2205	protein histidine kinase activity
AV941_14305	COG2080	2 iron, 2 sulfur cluster binding
AV941_14310	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AV941_14315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV941_14335	COG1028	Short-chain dehydrogenase reductase Sdr
AV941_14340	COG4221	oxidoreductase activity
AV941_14345	COG0693	protein deglycase activity
AV941_14350	COG1295	ribonuclease BN
AV941_14360	COG4681	YaeQ
AV941_14390	COG2814	Major facilitator Superfamily
AV941_14405	COG0514	ATP-dependent DNA helicase (RecQ)
AV941_14435	COG4251	negative regulation of phosphorylation
AV941_14440	COG2133	pyrroloquinoline quinone binding
AV941_14445	COG3609	addiction module antidote protein, CC2985 family
AV941_14475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV941_14480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV941_14495	COG0330	HflC and HflK could
AV941_14585	COG4772	TonB-dependent receptor
AV941_14670	COG4372	Transposase
AV941_14685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV941_14685	COG1017	nitric oxide dioxygenase activity
AV941_14690	COG3604	Transcriptional regulator
AV941_14720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AV941_14725	COG2971	BadF BadG BcrA BcrD
AV941_14730	COG0583	DNA-binding transcription factor activity
AV941_14735	COG1620	l-lactate permease
AV941_14755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV941_14760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV941_14765	COG0006	proline dipeptidase activity
AV941_14780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV941_14795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AV941_14800	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AV941_14805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV941_14825	COG3313	Fe-S protein
AV941_14860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_14865	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV941_14870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AV941_14875	COG2186	Transcriptional regulator
AV941_14885	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV941_14890	COG3577	Aspartyl protease
AV941_14895	COG0157	Belongs to the NadC ModD family
AV941_14905	COG1459	type II secretion system
AV941_14910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AV941_14920	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AV941_14930	COG3608	succinylglutamate desuccinylase aspartoacylase
AV941_14935	COG0494	nUDIX hydrolase
AV941_14945	COG0739	heme binding
AV941_14950	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AV941_14955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AV941_14960	COG0849	cell division
AV941_14965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AV941_14970	COG1181	Belongs to the D-alanine--D-alanine ligase family
AV941_14975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV941_14985	COG0772	Belongs to the SEDS family
AV941_14990	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AV941_15000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AV941_15005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV941_15010	COG0768	penicillin binding
AV941_15015	COG3116	cell division
AV941_15025	COG2001	Belongs to the MraZ family
AV941_15065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV941_15065	COG0678	peroxiredoxin activity
AV941_15080	COG3706	GGDEF domain
AV941_15090	COG2204	response regulator
AV941_15095	COG2205	protein histidine kinase activity
AV941_15095	COG0784	Response regulator, receiver
AV941_15120	COG0668	transmembrane transport
AV941_15125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AV941_15130	COG0189	ligase activity
AV941_15135	COG1678	Uncharacterized ACR, COG1678
AV941_15140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AV941_15165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AV941_15170	COG0762	integral membrane protein
AV941_15180	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV941_15180	COG1902	pentaerythritol trinitrate reductase activity
AV941_15195	COG0625	glutathione transferase activity
AV941_15205	COG1764	response to oxidative stress
AV941_15210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV941_15225	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AV941_15235	COG2814	Major facilitator Superfamily
AV941_15240	COG0724	RNA recognition motif
AV941_15265	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AV941_15270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AV941_15290	COG0583	DNA-binding transcription factor activity
AV941_15305	COG0640	Transcriptional regulator
AV941_15315	COG0431	NADPH-dependent FMN reductase
AV941_15320	COG0798	PFAM Bile acid sodium symporter
AV941_15325	COG2201	protein-glutamate methylesterase activity
AV941_15330	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AV941_15340	COG0642	Histidine kinase
AV941_15365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV941_15390	COG1748	Saccharopine dehydrogenase
AV941_15405	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AV941_15410	COG3107	peptidoglycan biosynthetic process
AV941_15420	COG0438	transferase activity, transferring glycosyl groups
AV941_15430	COG2823	Periplasmic or secreted lipoprotein
AV941_15450	COG4585	Histidine kinase
AV941_15455	COG2197	response regulator
AV941_15470	COG4771	TonB-dependent receptor
AV941_15480	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AV941_15485	COG0372	Belongs to the citrate synthase family
AV941_15490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AV941_15495	COG2828	Protein conserved in bacteria
AV941_15500	COG2199	diguanylate cyclase activity
AV941_15500	COG2203	Gaf domain
AV941_15505	COG1940	carbohydrate kinase activity
AV941_15545	COG0784	Response regulator, receiver
AV941_15545	COG2198	Histidine kinase
AV941_15545	COG5002	protein histidine kinase activity
AV941_15550	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV941_15555	COG0070	glutamate synthase
AV941_15555	COG0069	glutamate synthase activity
AV941_15555	COG0067	glutamate synthase
AV941_15560	COG0493	'glutamate synthase
AV941_15575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV941_15580	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AV941_15585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AV941_15590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV941_15605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV941_15610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AV941_15620	COG4942	peptidase
AV941_15625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AV941_15630	COG0738	Major facilitator superfamily
AV941_15640	COG1902	pentaerythritol trinitrate reductase activity
AV941_15660	COG0625	glutathione transferase activity
AV941_15685	COG2894	cell division
AV941_15690	COG0850	regulation of cytokinetic process
AV941_15700	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AV941_15730	COG1914	H( )-stimulated, divalent metal cation uptake system
AV941_15735	COG0436	Aminotransferase
AV941_15750	COG0174	glutamine synthetase
AV941_15760	COG3852	Histidine kinase
AV941_15765	COG2204	response regulator
AV941_15770	COG3437	response regulator, receiver
AV941_15775	COG0204	Acyl-transferase
AV941_15795	COG3920	Histidine kinase
AV941_15795	COG2202	Pas domain
AV941_15815	COG4999	Histidine kinase
AV941_15815	COG3850	Histidine kinase
AV941_15815	COG2205	protein histidine kinase activity
AV941_15815	COG3437	response regulator, receiver
AV941_15820	COG0525	valine-tRNA ligase activity
AV941_15825	COG2927	DNA polymerase III (CHI subunit)
AV941_15830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV941_15835	COG0795	lipopolysaccharide-transporting ATPase activity
AV941_15840	COG0795	lipopolysaccharide-transporting ATPase activity
AV941_15935	COG4974	Belongs to the 'phage' integrase family
AV941_15950	COG2856	Zn peptidase
AV941_16040	COG3250	beta-galactosidase activity
AV941_16050	COG4948	Mandelate Racemase Muconate Lactonizing
AV941_16055	COG3661	Belongs to the glycosyl hydrolase 67 family
AV941_16070	COG2203	Gaf domain
AV941_16070	COG2199	diguanylate cyclase activity
AV941_16100	COG0673	inositol 2-dehydrogenase activity
AV941_16110	COG0628	permease
AV941_16125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AV941_16130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV941_16135	COG4558	Periplasmic binding protein
AV941_16145	COG4206	TonB-dependent receptor
AV941_16155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AV941_16160	COG0697	spore germination
AV941_16185	COG1971	Probably functions as a manganese efflux pump
AV941_16195	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AV941_16210	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AV941_16220	COG0679	Auxin Efflux Carrier
AV941_16250	COG1131	(ABC) transporter
AV941_16260	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV941_16270	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AV941_16310	COG2205	protein histidine kinase activity
AV941_16320	COG0348	domain, Protein
AV941_16320	COG3901	Regulator of nitric oxide reductase transcription
AV941_16330	COG2197	response regulator
AV941_16355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV941_16370	COG4771	TonB-dependent receptor
AV941_16380	COG0583	DNA-binding transcription factor activity
AV941_16385	COG1304	FMN binding
AV941_16390	COG0277	FAD linked oxidase domain protein
AV941_16400	COG1462	curli production assembly transport component CsgG
AV941_16430	COG2197	response regulator
AV941_16445	COG0513	Belongs to the DEAD box helicase family
AV941_16475	COG2337	Toxic component of a toxin-antitoxin (TA) module
AV941_16505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV941_16530	COG2199	diguanylate cyclase activity
AV941_16530	COG2203	Gaf domain
AV941_16550	COG2124	cytochrome p450
AV941_16560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV941_16580	COG1271	oxidase subunit
AV941_16585	COG1294	oxidase, subunit
AV941_16590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV941_16605	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AV941_16605	COG3264	Mechanosensitive ion channel
AV941_16645	COG0730	response to heat
AV941_16665	COG4191	Histidine kinase
AV941_16675	COG0417	DNA replication proofreading
AV941_16685	COG0318	PFAM AMP-dependent synthetase and ligase
AV941_16725	COG1309	transcriptional regulator
AV941_16735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_16745	COG1573	uracil-dna glycosylase
AV941_16750	COG5001	Diguanylate cyclase
AV941_16750	COG3300	MHYT domain
AV941_16770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV941_16790	COG1983	PspC domain protein
AV941_16795	COG1842	Phage shock protein A
AV941_16805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV941_16825	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AV941_16825	COG2885	chlorophyll binding
AV941_16830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV941_16840	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AV941_16845	COG0204	Acyl-transferase
AV941_16850	COG0204	Acyl-transferase
AV941_16855	COG0668	transmembrane transport
AV941_16870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AV941_16875	COG0733	neurotransmitter:sodium symporter activity
AV941_16890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV941_16905	COG0716	FMN binding
AV941_16915	COG0848	biopolymer transport protein
AV941_16930	COG0457	Tetratricopeptide repeat
AV941_16935	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AV941_16945	COG1215	transferase activity, transferring glycosyl groups
AV941_16960	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AV941_16965	COG0702	epimerase
AV941_16980	COG5002	protein histidine kinase activity
AV941_16980	COG5001	Diguanylate cyclase
AV941_16995	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AV941_17005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_17015	COG0583	DNA-binding transcription factor activity
AV941_17020	COG0121	glutamine amidotransferase
AV941_17025	COG4682	membrane
AV941_17045	COG1953	Uracil, thiamine, allantoin
AV941_17050	COG4771	TonB-dependent receptor
AV941_17060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV941_17065	COG0778	Nitroreductase
AV941_17070	COG0596	Alpha beta hydrolase
AV941_17075	COG0251	oxidation-reduction process
AV941_17080	COG1335	isochorismatase
AV941_17085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV941_17090	COG1309	transcriptional regulator
AV941_17105	COG4628	conserved protein (DUF2132)
AV941_17110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV941_17120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AV941_17130	COG1477	protein flavinylation
AV941_17135	COG2871	sodium ion transport
AV941_17140	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_17145	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_17150	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_17155	COG1805	sodium ion transport
AV941_17160	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV941_17165	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AV941_17170	COG0545	Peptidyl-prolyl cis-trans isomerase
AV941_17175	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AV941_17180	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AV941_17195	COG0039	L-malate dehydrogenase activity
AV941_17200	COG1438	arginine binding
AV941_17225	COG0572	uridine kinase
AV941_17230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AV941_17250	COG0745	RESPONSE REGULATOR receiver
AV941_17250	COG3706	GGDEF domain
AV941_17255	COG2176	DNA-directed DNA polymerase activity
AV941_17260	COG1125	glycine betaine transport
AV941_17260	COG0517	IMP dehydrogenase activity
AV941_17265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV941_17275	COG2205	protein histidine kinase activity
AV941_17285	COG0189	ligase activity
AV941_17295	COG0189	ligase activity
AV941_17295	COG4067	protein conserved in archaea
AV941_17320	COG1283	sodium-dependent phosphate transmembrane transporter activity
AV941_17325	COG0667	Aldo Keto reductase
AV941_17340	COG5001	Diguanylate cyclase
AV941_17370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AV941_17380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AV941_17420	COG2274	protein secretion by the type I secretion system
AV941_17425	COG0583	DNA-binding transcription factor activity
AV941_17450	COG1216	Glycosyl transferase, family 2
AV941_17450	COG0438	transferase activity, transferring glycosyl groups
AV941_17490	COG0457	Tetratricopeptide repeat
AV941_17525	COG1216	Glycosyl transferase, family 2
AV941_17525	COG0463	Glycosyl transferase, family 2
AV941_17625	COG4372	Transposase
AV941_17675	COG2161	toxin-antitoxin pair type II binding
AV941_17685	COG0202	RNA polymerase activity
AV941_17710	COG0201	protein transport
AV941_17730	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AV941_17765	COG5002	protein histidine kinase activity
AV941_17765	COG0784	Response regulator, receiver
AV941_17790	COG0557	exoribonuclease II activity
AV941_17835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AV941_17850	COG0543	2 iron, 2 sulfur cluster binding
AV941_17865	COG2234	aminopeptidase activity
AV941_17875	COG4251	negative regulation of phosphorylation
AV941_17885	COG1271	oxidase subunit
AV941_17890	COG1294	oxidase, subunit
AV941_17895	COG1522	sequence-specific DNA binding
AV941_17905	COG1278	Cold shock
AV941_17910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV941_17930	COG0339	signal peptide processing
AV941_17935	COG2201	protein-glutamate methylesterase activity
AV941_17945	COG3852	Histidine kinase
AV941_17955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV941_17960	COG0243	molybdopterin cofactor binding
AV941_17965	COG0823	Involved in the tonB-independent uptake of proteins
AV941_17965	COG1506	peptidase
AV941_17965	COG4946	Tricorn protease homolog
AV941_18010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV941_18020	COG2197	response regulator
AV941_18030	COG0189	ligase activity
AV941_18050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AV941_18055	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV941_18060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AV941_18075	COG0281	malic enzyme
AV941_18085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AV941_18115	COG0456	acetyltransferase
AV941_18125	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV941_18130	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV941_18135	COG2177	Part of the ABC transporter FtsEX involved in
AV941_18140	COG2884	Cell division ATP-binding protein ftsE
AV941_18145	COG0552	protein localization to endoplasmic reticulum
AV941_18150	COG0742	ribosomal rna small subunit methyltransferase
AV941_18160	COG2095	MarC family integral membrane protein
AV941_18180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AV941_18185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV941_18190	COG0617	tRNA 3'-terminal CCA addition
AV941_18195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AV941_18210	COG0076	glutamate decarboxylase activity
AV941_18225	COG0842	Transport permease protein
AV941_18230	COG1131	(ABC) transporter
AV941_18235	COG0745	RESPONSE REGULATOR receiver
AV941_18240	COG2205	protein histidine kinase activity
AV941_18245	COG4774	siderophore transport
AV941_18265	COG1253	flavin adenine dinucleotide binding
AV941_18275	COG1966	Carbon starvation protein
AV941_18300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV941_18305	COG0049	tRNA binding
AV941_18310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AV941_18315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AV941_18320	COG0085	RNA polymerase activity
AV941_18325	COG0222	ribosome binding
AV941_18330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AV941_18335	COG0081	regulation of translation
AV941_18340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AV941_18360	COG0250	Participates in transcription elongation, termination and antitermination
AV941_18365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV941_18375	COG1132	(ABC) transporter
AV941_18380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AV941_18385	COG3590	peptidase
AV941_18395	COG0513	Belongs to the DEAD box helicase family
AV941_18400	COG0418	dihydroorotase activity
AV941_18405	COG3040	lipid binding
AV941_18410	COG4989	oxidoreductase activity
AV941_18415	COG0346	lactoylglutathione lyase activity
AV941_18420	COG0668	transmembrane transport
AV941_18440	COG0302	gtp cyclohydrolase
AV941_18450	COG2957	Belongs to the agmatine deiminase family
AV941_18455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV941_18470	COG1201	RNA secondary structure unwinding
AV941_18480	COG1793	dna ligase
AV941_18485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV941_18490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV941_18500	COG1410	methionine synthase
AV941_18500	COG0646	methionine synthase
AV941_18505	COG0625	glutathione transferase activity
AV941_18510	COG0625	glutathione transferase activity
AV941_18520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AV941_18535	COG1012	belongs to the aldehyde dehydrogenase family
AV941_18540	COG0028	Belongs to the TPP enzyme family
AV941_18550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AV941_18555	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AV941_18560	COG0330	HflC and HflK could
AV941_18565	COG0330	HflC and HflK could
AV941_18570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AV941_18575	COG1923	regulation of RNA biosynthetic process
AV941_18580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AV941_18595	COG0802	atpase or kinase
AV941_18600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AV941_18600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AV941_18605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AV941_18615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AV941_18625	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AV941_18630	COG0735	belongs to the Fur family
AV941_18640	COG0432	Pfam Uncharacterised protein family UPF0047
AV941_18650	COG0305	Participates in initiation and elongation during chromosome replication
AV941_18675	COG2258	MOSC domain
AV941_18705	COG2205	protein histidine kinase activity
AV941_18725	COG0840	transmembrane signaling receptor activity
AV941_18730	COG5002	protein histidine kinase activity
AV941_18735	COG0840	transmembrane signaling receptor activity
AV941_18765	COG1472	Belongs to the glycosyl hydrolase 3 family
AV941_18775	COG2723	6-phospho-beta-galactosidase activity
AV941_18780	COG1609	Transcriptional regulator
AV941_18785	COG0477	Major facilitator Superfamily
AV941_18785	COG2814	Major facilitator Superfamily
AV941_18790	COG4319	ketosteroid isomerase
AV941_18810	COG2375	cellular response to nickel ion
AV941_18815	COG3237	CsbD-like
AV941_18845	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV941_18845	COG0596	Alpha beta hydrolase
AV941_18865	COG3038	cytochrome b561
AV941_18875	COG1252	NADH dehydrogenase
AV941_18890	COG0583	DNA-binding transcription factor activity
AV941_18895	COG2067	long-chain fatty acid transport protein
AV941_18900	COG2130	NADP-dependent
AV941_18905	COG2203	Gaf domain
AV941_18905	COG4251	negative regulation of phosphorylation
AV941_18905	COG5001	Diguanylate cyclase
AV941_18905	COG3706	GGDEF domain
AV941_18910	COG0784	Response regulator, receiver
AV941_18910	COG2205	protein histidine kinase activity
AV941_18920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV941_18925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AV941_18930	COG1349	DNA-binding transcription factor activity
AV941_18935	COG0673	inositol 2-dehydrogenase activity
AV941_18950	COG0697	spore germination
AV941_18955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV941_18960	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AV941_18965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AV941_18970	COG1166	arginine decarboxylase activity
AV941_18980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AV941_18985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV941_18990	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV941_19060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV941_19065	COG0109	protoheme IX farnesyltransferase activity
AV941_19085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV941_19130	COG3030	protein affecting phage T7 exclusion by the F plasmid
AV941_19135	COG1324	tolerance protein
AV941_19140	COG4232	protein-disulfide reductase activity
AV941_19145	COG0739	heme binding
AV941_19150	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AV941_19155	COG0511	ligase activity, forming carbon-carbon bonds
AV941_19160	COG0439	Biotin carboxylase
AV941_19205	COG0154	amidase activity
AV941_19220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV941_19225	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AV941_19240	COG0151	Belongs to the GarS family
AV941_19255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV941_19260	COG3954	Phosphoribulokinase
AV941_19270	COG0745	RESPONSE REGULATOR receiver
AV941_19285	COG1501	Belongs to the glycosyl hydrolase 31 family
AV941_19295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AV941_19305	COG3031	protein transport across the cell outer membrane
AV941_19315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV941_19320	COG1459	type II secretion system
AV941_19325	COG2165	general secretion pathway protein
AV941_19330	COG2165	general secretion pathway protein
AV941_19340	COG4795	General secretion pathway protein
AV941_19355	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AV941_19370	COG1012	belongs to the aldehyde dehydrogenase family
AV941_19380	COG1011	Hydrolase
AV941_19385	COG0494	nUDIX hydrolase
AV941_19390	COG1218	3'(2'),5'-bisphosphate nucleotidase
AV941_19405	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AV941_19415	COG3089	Belongs to the UPF0270 family
AV941_19420	COG0429	hydrolase of the alpha beta-hydrolase fold
AV941_19430	COG0488	(ABC) transporter
AV941_19445	COG2900	Belongs to the SlyX family
AV941_19455	COG0545	Peptidyl-prolyl cis-trans isomerase
AV941_19465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV941_19470	COG2183	response to ionizing radiation
AV941_19495	COG1609	Transcriptional regulator
AV941_19495	COG2207	Transcriptional regulator
AV941_19500	COG2211	Major facilitator Superfamily
AV941_19515	COG3693	PFAM glycoside hydrolase, family 10
AV941_19520	COG0667	Aldo Keto reductase
AV941_19525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV941_19530	COG2115	Belongs to the xylose isomerase family
AV941_19535	COG1070	Carbohydrate kinase
AV941_19550	COG1472	Belongs to the glycosyl hydrolase 3 family
AV941_19555	COG0477	Major facilitator Superfamily
AV941_19600	COG0596	Alpha beta hydrolase
AV941_19605	COG1040	competence protein
AV941_19625	COG1794	racemase activity, acting on amino acids and derivatives
AV941_19635	COG0534	Mate efflux family protein
AV941_19650	COG1999	signal sequence binding
AV941_19655	COG0109	protoheme IX farnesyltransferase activity
AV941_19660	COG1612	heme a metabolic process
AV941_19680	COG1845	cytochrome c oxidase, subunit III
AV941_19685	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AV941_19690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV941_19695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV941_19715	COG0129	dihydroxy-acid dehydratase activity
AV941_19725	COG0606	chelatase, subunit chli
AV941_19730	COG0583	DNA-binding transcription factor activity
AV941_19740	COG2814	Major facilitator Superfamily
AV941_19750	COG0729	surface antigen
AV941_19755	COG2911	Protein conserved in bacteria
AV941_19780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV941_19790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV941_19810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV941_19835	COG1228	amidohydrolase
AV941_19860	COG0425	Belongs to the sulfur carrier protein TusA family
AV941_19875	COG1561	YicC-like family, N-terminal region
AV941_19885	COG3550	peptidyl-serine autophosphorylation
AV941_19890	COG3620	sequence-specific DNA binding
AV941_19975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV941_20005	COG5433	transposase activity
AV941_20010	COG3119	arylsulfatase activity
AV941_20015	COG0714	Associated with various cellular activities
AV941_20030	COG2304	oxidoreductase activity
AV941_20065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV941_20075	COG1960	acyl-CoA dehydrogenase activity
AV941_20085	COG1024	Enoyl-CoA hydratase
AV941_20095	COG2801	Transposase and inactivated derivatives
AV941_20110	COG0129	dihydroxy-acid dehydratase activity
AV941_20130	COG3177	Filamentation induced by cAMP protein fic
AV941_20140	COG1609	Transcriptional regulator
AV941_20155	COG2199	diguanylate cyclase activity
AV941_20155	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AV941_20180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AV941_20200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AV941_20205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AV941_20225	COG1475	DNA binding
AV941_20230	COG1192	Involved in chromosome partitioning
AV941_20255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV941_20260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AV941_20270	COG0706	membrane insertase activity
AV941_20275	COG0594	ribonuclease P activity
AV941_20280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AV941_20825	COG1132	(ABC) transporter
AV941_20845	COG2801	Transposase and inactivated derivatives
AV941_20925	COG2201	protein-glutamate methylesterase activity
AV941_20980	COG5290	Psort location Cytoplasmic, score
AV941_21010	COG3209	COG3209 Rhs family protein
AV941_21020	COG3209	COG3209 Rhs family protein
AV941_21140	COG5310	Homospermidine synthase
AV941_21165	COG3251	PFAM MbtH domain protein
AV941_21335	COG0210	DNA helicase
AV941_21375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV941_21405	COG4584	PFAM Integrase catalytic
AV941_21410	COG1484	DNA-dependent DNA replication
AV941_21420	COG5001	Diguanylate cyclase
AV941_21420	COG3300	MHYT domain
AV941_21435	COG3706	GGDEF domain
AV941_21520	COG1192	Involved in chromosome partitioning