locus-tag	class	description
AV942_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AV942_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AV942_00020	COG0187	DNA topoisomerase II activity
AV942_00040	COG2818	Glycosylase
AV942_00050	COG3078	GTPase activator activity
AV942_00070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV942_00070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV942_00075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AV942_00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AV942_00085	COG0569	domain protein
AV942_00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV942_00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV942_00095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AV942_00110	COG0758	DNA mediated transformation
AV942_00125	COG0009	L-threonylcarbamoyladenylate synthase
AV942_00130	COG0408	coproporphyrinogen oxidase activity
AV942_00135	COG3047	cAMP biosynthetic process
AV942_00150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AV942_00225	COG2234	aminopeptidase activity
AV942_00230	COG0463	Glycosyl transferase, family 2
AV942_00240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AV942_00265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV942_00295	COG3642	lipopolysaccharide core region biosynthetic process
AV942_00300	COG0859	PFAM glycosyl transferase family 9
AV942_00330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV942_00345	COG3161	chorismate lyase activity
AV942_00350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AV942_00370	COG0210	DNA helicase
AV942_00415	COG1959	2 iron, 2 sulfur cluster binding
AV942_00420	COG0730	response to heat
AV942_00435	COG4771	TonB-dependent receptor
AV942_00450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AV942_00455	COG4988	ABC transporter
AV942_00465	COG1271	oxidase subunit
AV942_00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV942_00475	COG0425	Belongs to the sulfur carrier protein TusA family
AV942_00485	COG0450	alkyl hydroperoxide reductase
AV942_00495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV942_00525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV942_00570	COG0270	DNA (cytosine-5-)-methyltransferase activity
AV942_00575	COG0556	nucleotide-excision repair
AV942_00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_00590	COG1129	ABC transporter
AV942_00590	COG0842	Transport permease protein
AV942_00595	COG0842	Transport permease protein
AV942_00610	COG1960	acyl-CoA dehydrogenase activity
AV942_00615	COG0583	DNA-binding transcription factor activity
AV942_00625	COG3106	COG3106 Predicted ATPase
AV942_00640	COG2184	nucleotidyltransferase activity
AV942_00645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AV942_00660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AV942_00665	COG0352	thiamine-phosphate diphosphorylase activity
AV942_00675	COG3071	HemY protein
AV942_00680	COG2959	enzyme of heme biosynthesis
AV942_00690	COG0181	hydroxymethylbilane synthase activity
AV942_00705	COG0194	GDP metabolic process
AV942_00715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV942_00725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV942_00730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AV942_00740	COG0678	peroxiredoxin activity
AV942_00755	COG1178	ABC-type Fe3 transport system permease component
AV942_00760	COG3842	ATPase activity
AV942_00765	COG0668	transmembrane transport
AV942_00770	COG2081	HI0933 family
AV942_00790	COG2963	transposase activity
AV942_00825	COG0789	Transcriptional regulator
AV942_00830	COG2963	transposase activity
AV942_00835	COG2801	Transposase and inactivated derivatives
AV942_00850	COG2200	EAL domain
AV942_00855	COG0583	DNA-binding transcription factor activity
AV942_00865	COG2076	Multidrug Resistance protein
AV942_00880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_00895	COG0427	acetyl-CoA hydrolase
AV942_00900	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV942_00915	COG0840	transmembrane signaling receptor activity
AV942_00925	COG3064	Membrane
AV942_00935	COG5002	protein histidine kinase activity
AV942_00935	COG5001	Diguanylate cyclase
AV942_00950	COG0514	ATP-dependent DNA helicase (RecQ)
AV942_00955	COG2239	Acts as a magnesium transporter
AV942_00960	COG2962	Rard protein
AV942_00965	COG3706	GGDEF domain
AV942_00965	COG0745	RESPONSE REGULATOR receiver
AV942_00970	COG0210	DNA helicase
AV942_00980	COG1011	Hydrolase
AV942_00995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AV942_01000	COG0019	diaminopimelate decarboxylase activity
AV942_01030	COG0163	prenyltransferase activity
AV942_01035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV942_01045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AV942_01065	COG1077	Cell shape determining protein MreB Mrl
AV942_01070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AV942_01075	COG2814	Major facilitator Superfamily
AV942_01080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV942_01105	COG1085	galactose-1-phosphate uridylyltransferase
AV942_01110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AV942_01120	COG0629	single-stranded DNA binding
AV942_01135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV942_01140	COG3250	beta-galactosidase activity
AV942_01160	COG1349	DNA-binding transcription factor activity
AV942_01205	COG3409	Peptidoglycan-binding domain 1 protein
AV942_01205	COG3267	Type II secretory pathway component ExeA
AV942_01220	COG1459	type II secretion system
AV942_01265	COG1077	Cell shape determining protein MreB Mrl
AV942_01270	COG1792	Involved in formation and maintenance of cell shape
AV942_01275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AV942_01285	COG1530	ribonuclease E activity
AV942_01295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV942_01300	COG0312	modulator of DNA gyrase
AV942_01305	COG3028	Belongs to the UPF0307 family
AV942_01310	COG0312	modulator of DNA gyrase
AV942_01320	COG0745	RESPONSE REGULATOR receiver
AV942_01325	COG4191	Histidine kinase
AV942_01325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV942_01330	COG0297	glycogen (starch) synthase activity
AV942_01340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AV942_01345	COG0596	Alpha beta hydrolase
AV942_01370	COG5002	protein histidine kinase activity
AV942_01375	COG0745	RESPONSE REGULATOR receiver
AV942_01395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV942_01485	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AV942_01515	COG0375	protein maturation
AV942_01525	COG0409	Hydrogenase expression formation protein
AV942_01535	COG0309	Hydrogenase expression formation protein (HypE)
AV942_01540	COG0789	Transcriptional regulator
AV942_01545	COG2217	Heavy metal translocating P-type atpase
AV942_01630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV942_01640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV942_01650	COG0463	Glycosyl transferase, family 2
AV942_01655	COG0745	RESPONSE REGULATOR receiver
AV942_01660	COG5002	protein histidine kinase activity
AV942_01695	COG0789	Transcriptional regulator
AV942_01700	COG2217	Heavy metal translocating P-type atpase
AV942_01735	COG0531	amino acid
AV942_01745	COG2132	Multicopper oxidase
AV942_01830	COG0546	phosphoglycolate phosphatase activity
AV942_01850	COG1609	Transcriptional regulator
AV942_01855	COG0673	inositol 2-dehydrogenase activity
AV942_01865	COG2211	Major facilitator Superfamily
AV942_01890	COG1454	alcohol dehydrogenase
AV942_01965	COG0089	rRNA binding
AV942_01975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AV942_01985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AV942_02000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AV942_02005	COG0438	transferase activity, transferring glycosyl groups
AV942_02015	COG1519	Transferase
AV942_02050	COG0788	formyltetrahydrofolate deformylase activity
AV942_02060	COG1643	Atp-dependent helicase
AV942_02065	COG2951	lytic endotransglycosylase activity
AV942_02070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV942_02080	COG2354	Protein conserved in bacteria
AV942_02085	COG4977	sequence-specific DNA binding
AV942_02100	COG0004	ammonium transporteR
AV942_02105	COG0405	Gamma-glutamyltransferase
AV942_02110	COG2837	iron assimilation
AV942_02125	COG0540	Belongs to the ATCase OTCase family
AV942_02150	COG2205	protein histidine kinase activity
AV942_02150	COG5002	protein histidine kinase activity
AV942_02150	COG0784	Response regulator, receiver
AV942_02165	COG5001	Diguanylate cyclase
AV942_02165	COG3300	MHYT domain
AV942_02175	COG1012	belongs to the aldehyde dehydrogenase family
AV942_02185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV942_02200	COG0180	Tryptophanyl-tRNA synthetase
AV942_02205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AV942_02225	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AV942_02235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AV942_02270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AV942_02275	COG0281	malic enzyme
AV942_02285	COG0625	glutathione transferase activity
AV942_02295	COG0753	catalase activity
AV942_02310	COG5001	Diguanylate cyclase
AV942_02310	COG3300	MHYT domain
AV942_02315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV942_02315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AV942_02325	COG0137	argininosuccinate synthase activity
AV942_02345	COG1803	Methylglyoxal synthase
AV942_02355	COG0745	RESPONSE REGULATOR receiver
AV942_02360	COG2205	protein histidine kinase activity
AV942_02365	COG2267	carboxylic ester hydrolase activity
AV942_02370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AV942_02380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AV942_02390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV942_02395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV942_02400	COG4942	peptidase
AV942_02405	COG2861	carbohydrate metabolic process
AV942_02430	COG1162	GTPase activity
AV942_02435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AV942_02465	COG0028	Belongs to the TPP enzyme family
AV942_02485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV942_02490	COG0805	protein transport
AV942_02500	COG0084	hydrolase, TatD family'
AV942_02505	COG2203	Gaf domain
AV942_02505	COG4251	negative regulation of phosphorylation
AV942_02505	COG5001	Diguanylate cyclase
AV942_02505	COG3706	GGDEF domain
AV942_02515	COG0248	Ppx GppA phosphatase
AV942_02520	COG0513	Belongs to the DEAD box helicase family
AV942_02525	COG3118	belongs to the thioredoxin family
AV942_02530	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AV942_02540	COG0784	Response regulator, receiver
AV942_02540	COG5002	protein histidine kinase activity
AV942_02545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AV942_02555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AV942_02570	COG0783	Belongs to the Dps family
AV942_02575	COG2133	pyrroloquinoline quinone binding
AV942_02580	COG0823	Involved in the tonB-independent uptake of proteins
AV942_02580	COG4946	Tricorn protease homolog
AV942_02580	COG1506	peptidase
AV942_02590	COG3118	belongs to the thioredoxin family
AV942_02605	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AV942_02615	COG1012	belongs to the aldehyde dehydrogenase family
AV942_02635	COG1757	Na H antiporter
AV942_02650	COG3876	Protein conserved in bacteria
AV942_02655	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AV942_02665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AV942_02675	COG0346	lactoylglutathione lyase activity
AV942_02700	COG2824	Alkylphosphonate utilization operon protein PhnA
AV942_02705	COG0454	-acetyltransferase
AV942_02735	COG3093	addiction module antidote protein HigA
AV942_02750	COG2026	Addiction module toxin, RelE StbE family
AV942_02840	COG0183	Belongs to the thiolase family
AV942_02845	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV942_02845	COG1024	Enoyl-CoA hydratase
AV942_02855	COG0006	proline dipeptidase activity
AV942_02865	COG0142	geranyltranstransferase activity
AV942_02895	COG1388	LysM domain
AV942_02895	COG4942	peptidase
AV942_02900	COG1238	metal cluster binding
AV942_02910	COG0585	pseudouridine synthase activity
AV942_02915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AV942_02925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AV942_02935	COG0840	transmembrane signaling receptor activity
AV942_02970	COG0494	nUDIX hydrolase
AV942_02975	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AV942_02980	COG0730	response to heat
AV942_02985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AV942_02990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AV942_03000	COG0745	RESPONSE REGULATOR receiver
AV942_03000	COG3706	GGDEF domain
AV942_03025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AV942_03035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AV942_03045	COG1648	precorrin-2 dehydrogenase activity
AV942_03045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV942_03050	COG0513	Belongs to the DEAD box helicase family
AV942_03065	COG1538	Outer membrane efflux protein
AV942_03070	COG0494	nUDIX hydrolase
AV942_03080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AV942_03085	COG3150	esterase
AV942_03090	COG0187	DNA topoisomerase II activity
AV942_03100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV942_03125	COG1509	lysine 2,3-aminomutase activity
AV942_03135	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AV942_03150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV942_03165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV942_03180	COG0271	Belongs to the BolA IbaG family
AV942_03195	COG3707	response regulator
AV942_03210	COG0659	secondary active sulfate transmembrane transporter activity
AV942_03215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AV942_03225	COG0243	molybdopterin cofactor binding
AV942_03230	COG1648	precorrin-2 dehydrogenase activity
AV942_03230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV942_03235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV942_03245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AV942_03245	COG1116	anion transmembrane transporter activity
AV942_03255	COG1116	anion transmembrane transporter activity
AV942_03270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV942_03275	COG4206	TonB-dependent receptor
AV942_03285	COG0348	domain, Protein
AV942_03300	COG1960	acyl-CoA dehydrogenase activity
AV942_03305	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_03315	COG4948	Mandelate Racemase Muconate Lactonizing
AV942_03330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_03335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV942_03355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV942_03360	COG0358	DNA primase activity
AV942_03385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AV942_03390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV942_03405	COG0537	adenosine 5'-monophosphoramidase activity
AV942_03420	COG3135	benzoate transporter
AV942_03425	COG1396	sequence-specific DNA binding
AV942_03430	COG2974	May be involved in recombination
AV942_03435	COG4191	Histidine kinase
AV942_03435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV942_03440	COG0745	RESPONSE REGULATOR receiver
AV942_03445	COG5002	protein histidine kinase activity
AV942_03470	COG0811	peptide transport
AV942_03475	COG0811	peptide transport
AV942_03480	COG0848	biopolymer transport protein
AV942_03485	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AV942_03495	COG3437	response regulator, receiver
AV942_03505	COG0318	PFAM AMP-dependent synthetase and ligase
AV942_03515	COG2133	pyrroloquinoline quinone binding
AV942_03525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV942_03550	COG0527	aspartate kinase activity
AV942_03555	COG0840	transmembrane signaling receptor activity
AV942_03560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV942_03565	COG2967	ApaG domain
AV942_03575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AV942_03580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV942_03585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AV942_03590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AV942_03600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV942_03620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AV942_03635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV942_03640	COG3956	TIGRFAM MazG family protein
AV942_03665	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_03675	COG0318	PFAM AMP-dependent synthetase and ligase
AV942_03685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AV942_03695	COG0463	Glycosyl transferase, family 2
AV942_03715	COG0642	Histidine kinase
AV942_03720	COG0745	RESPONSE REGULATOR receiver
AV942_03735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV942_03740	COG0723	plastoquinol--plastocyanin reductase activity
AV942_03745	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AV942_03750	COG2857	Cytochrome c1
AV942_03755	COG0625	glutathione transferase activity
AV942_03760	COG2969	positive regulation of protein catabolic process
AV942_03765	COG2239	Acts as a magnesium transporter
AV942_03770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV942_03780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV942_03790	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AV942_03795	COG1137	ATPase activity
AV942_03800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AV942_03810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AV942_03825	COG1127	ABC transporter
AV942_03830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV942_03835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV942_03840	COG2854	intermembrane phospholipid transfer
AV942_03850	COG5007	Belongs to the BolA IbaG family
AV942_03860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV942_03865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV942_03875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AV942_03915	COG4771	TonB-dependent receptor
AV942_03920	COG0697	spore germination
AV942_03930	COG2205	protein histidine kinase activity
AV942_03930	COG0784	Response regulator, receiver
AV942_03955	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV942_03965	COG0126	phosphoglycerate kinase activity
AV942_03970	COG3588	fructose-bisphosphate aldolase
AV942_03980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_03990	COG1538	Outer membrane efflux protein
AV942_03995	COG0823	Involved in the tonB-independent uptake of proteins
AV942_03995	COG4946	Tricorn protease homolog
AV942_03995	COG1506	peptidase
AV942_04000	COG0248	Ppx GppA phosphatase
AV942_04005	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AV942_04015	COG0573	inorganic phosphate transmembrane transporter activity
AV942_04025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV942_04035	COG0306	phosphate transporter
AV942_04045	COG0583	DNA-binding transcription factor activity
AV942_04055	COG1272	protein, Hemolysin III
AV942_04060	COG1846	Transcriptional regulator
AV942_04065	COG1764	response to oxidative stress
AV942_04085	COG1739	Uncharacterized protein family UPF0029
AV942_04105	COG0420	3'-5' exonuclease activity
AV942_04110	COG0419	ATPase involved in DNA repair
AV942_04120	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AV942_04145	COG2986	histidine ammonia-lyase
AV942_04170	COG0488	(ABC) transporter
AV942_04190	COG0668	transmembrane transport
AV942_04250	COG0582	viral genome integration into host DNA
AV942_04255	COG4372	Transposase
AV942_04350	COG1484	DNA-dependent DNA replication
AV942_04360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AV942_04375	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AV942_04425	COG1346	cytolysis
AV942_04455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV942_04465	COG0513	Belongs to the DEAD box helicase family
AV942_04475	COG3409	Peptidoglycan-binding domain 1 protein
AV942_04475	COG3267	Type II secretory pathway component ExeA
AV942_04490	COG0066	3-isopropylmalate dehydratase activity
AV942_04500	COG0473	3-isopropylmalate dehydrogenase activity
AV942_04505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV942_04525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AV942_04540	COG4555	ABC transporter
AV942_04545	COG1668	transmembrane transport
AV942_04565	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV942_04570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV942_04575	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV942_04585	COG1138	Cytochrome C-type biogenesis protein
AV942_04590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV942_04605	COG2853	Lipoprotein
AV942_04610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV942_04620	COG3104	oligopeptide transport
AV942_04650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AV942_04665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AV942_04670	COG1555	photosystem II stabilization
AV942_04670	COG1596	polysaccharide export
AV942_04675	COG0473	3-isopropylmalate dehydrogenase activity
AV942_04690	COG1611	Belongs to the LOG family
AV942_04695	COG3706	GGDEF domain
AV942_04695	COG0745	RESPONSE REGULATOR receiver
AV942_04700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV942_04700	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV942_04755	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AV942_04760	COG0024	Methionine aminopeptidase
AV942_04765	COG0052	Belongs to the universal ribosomal protein uS2 family
AV942_04775	COG0528	UMP kinase activity
AV942_04785	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV942_04790	COG0575	Belongs to the CDS family
AV942_04815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV942_04835	COG0587	DNA-directed DNA polymerase activity
AV942_04840	COG0825	malonyl-CoA metabolic process
AV942_04845	COG0037	tRNA processing
AV942_04865	COG0590	tRNA wobble adenosine to inosine editing
AV942_04875	COG0047	phosphoribosylformylglycinamidine synthase activity
AV942_04875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AV942_04880	COG2840	Smr protein MutS2
AV942_04910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_04915	COG2197	response regulator
AV942_04950	COG0784	Response regulator, receiver
AV942_04950	COG0835	chemotaxis
AV942_04955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AV942_04960	COG1815	bacterial-type flagellum-dependent cell motility
AV942_04965	COG1558	bacterial-type flagellum-dependent cell motility
AV942_04970	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AV942_04975	COG1749	Flagellar hook protein flgE
AV942_04980	COG4787	bacterial-type flagellum-dependent cell motility
AV942_04985	COG4786	Flagellar basal body rod
AV942_05000	COG3951	Flagellar rod assembly protein muramidase FlgJ
AV942_05000	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV942_05005	COG1256	bacterial-type flagellum assembly
AV942_05025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV942_05030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV942_05045	COG1516	flagellar protein fliS
AV942_05060	COG1086	Polysaccharide biosynthesis protein
AV942_05065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AV942_05075	COG2089	acid synthase
AV942_05090	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_05095	COG0318	PFAM AMP-dependent synthetase and ligase
AV942_05140	COG1660	Displays ATPase and GTPase activities
AV942_05145	COG1216	Glycosyl transferase, family 2
AV942_05160	COG1083	cytidylyl-transferase
AV942_05170	COG2204	response regulator
AV942_05175	COG3852	Histidine kinase
AV942_05180	COG2204	response regulator
AV942_05185	COG1677	Flagellar hook-basal body complex protein FliE
AV942_05190	COG1766	The M ring may be actively involved in energy transduction
AV942_05195	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV942_05245	COG1987	bacterial-type flagellum assembly
AV942_05260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV942_05270	COG0455	bacterial-type flagellum organization
AV942_05285	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AV942_05290	COG2198	Histidine kinase
AV942_05290	COG0643	Histidine kinase
AV942_05300	COG1192	Involved in chromosome partitioning
AV942_05310	COG0835	chemotaxis
AV942_05325	COG0646	methionine synthase
AV942_05325	COG1410	methionine synthase
AV942_05330	COG1410	methionine synthase
AV942_05330	COG0646	methionine synthase
AV942_05340	COG3123	guanosine phosphorylase activity
AV942_05345	COG0583	DNA-binding transcription factor activity
AV942_05350	COG0583	DNA-binding transcription factor activity
AV942_05360	COG0659	secondary active sulfate transmembrane transporter activity
AV942_05375	COG3590	peptidase
AV942_05385	COG2137	regulation of response to DNA damage stimulus
AV942_05390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AV942_05420	COG0511	ligase activity, forming carbon-carbon bonds
AV942_05420	COG5016	pyruvate
AV942_05425	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AV942_05430	COG4172	Belongs to the ABC transporter superfamily
AV942_05440	COG4171	peptide transport system, permease
AV942_05445	COG4168	peptide transport system, permease
AV942_05450	COG0747	negative chemotaxis
AV942_05455	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AV942_05460	COG1842	Phage shock protein A
AV942_05490	COG0625	glutathione transferase activity
AV942_05495	COG1522	sequence-specific DNA binding
AV942_05560	COG0811	peptide transport
AV942_05565	COG0811	peptide transport
AV942_05570	COG0848	biopolymer transport protein
AV942_05585	COG1444	tRNA N-acetyltransferase activity
AV942_05625	COG0456	acetyltransferase
AV942_05640	COG0583	DNA-binding transcription factor activity
AV942_05645	COG2814	Major facilitator Superfamily
AV942_05650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV942_05655	COG0656	L-ascorbic acid biosynthetic process
AV942_05675	COG1846	Transcriptional regulator
AV942_05685	COG3620	sequence-specific DNA binding
AV942_05690	COG3550	peptidyl-serine autophosphorylation
AV942_05725	COG0668	transmembrane transport
AV942_05735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AV942_05755	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AV942_05835	COG0789	Transcriptional regulator
AV942_05850	COG0789	Transcriptional regulator
AV942_05855	COG0640	Transcriptional regulator
AV942_05865	COG1230	cation diffusion facilitator family transporter
AV942_05890	COG1538	Outer membrane efflux protein
AV942_05900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV942_05915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV942_05930	COG0681	Belongs to the peptidase S26 family
AV942_05950	COG1074	ATP-dependent DNA helicase activity
AV942_05960	COG1404	Belongs to the peptidase S8 family
AV942_05965	COG0464	growth
AV942_05985	COG0629	single-stranded DNA binding
AV942_06000	COG0714	Associated with various cellular activities
AV942_06025	COG2003	Belongs to the UPF0758 family
AV942_06045	COG0583	DNA-binding transcription factor activity
AV942_06135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV942_06145	COG3706	GGDEF domain
AV942_06185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AV942_06190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AV942_06195	COG0564	pseudouridine synthase activity
AV942_06205	COG0612	Peptidase, M16
AV942_06210	COG2918	glutathione biosynthetic process
AV942_06230	COG2840	Smr protein MutS2
AV942_06235	COG2890	protein-(glutamine-N5) methyltransferase activity
AV942_06250	COG2719	SpoVR family
AV942_06255	COG2718	Belongs to the UPF0229 family
AV942_06260	COG2766	serine protein kinase
AV942_06270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AV942_06275	COG4771	TonB-dependent receptor
AV942_06300	COG0450	alkyl hydroperoxide reductase
AV942_06305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV942_06310	COG2885	chlorophyll binding
AV942_06315	COG0584	glycerophosphoryl diester phosphodiesterase
AV942_06320	COG0346	lactoylglutathione lyase activity
AV942_06325	COG1278	Cold shock
AV942_06340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AV942_06345	COG4660	Part of a membrane complex involved in electron transport
AV942_06350	COG4659	FMN binding
AV942_06355	COG4658	electron transport chain
AV942_06360	COG4656	Part of a membrane complex involved in electron transport
AV942_06365	COG2878	Part of a membrane complex involved in electron transport
AV942_06385	COG0534	Mate efflux family protein
AV942_06390	COG0556	nucleotide-excision repair
AV942_06405	COG0602	queuosine metabolic process
AV942_06415	COG0367	asparagine synthase
AV942_06440	COG0471	metal ion transport
AV942_06440	COG3273	potassium ion transport
AV942_06455	COG0529	Catalyzes the synthesis of activated sulfate
AV942_06460	COG0175	sulfate reduction
AV942_06465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV942_06470	COG3706	GGDEF domain
AV942_06495	COG2304	oxidoreductase activity
AV942_06515	COG0714	Associated with various cellular activities
AV942_06525	COG1024	Enoyl-CoA hydratase
AV942_06525	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV942_06540	COG1025	Belongs to the peptidase M16 family
AV942_06545	COG2062	phosphohistidine phosphatase, SixA
AV942_06555	COG4536	flavin adenine dinucleotide binding
AV942_06560	COG4137	Cytochrome C assembly protein
AV942_06565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AV942_06610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_06615	COG1132	(ABC) transporter
AV942_06630	COG0228	four-way junction DNA binding
AV942_06635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AV942_06640	COG0336	Belongs to the RNA methyltransferase TrmD family
AV942_06645	COG0335	large ribosomal subunit rRNA binding
AV942_06650	COG2860	membrane
AV942_06660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AV942_06665	COG0287	Prephenate dehydrogenase
AV942_06665	COG1605	Chorismate mutase
AV942_06670	COG1605	Chorismate mutase
AV942_06670	COG0077	Prephenate dehydratase
AV942_06680	COG0023	Translation Initiation Factor
AV942_06710	COG2205	protein histidine kinase activity
AV942_06720	COG2204	response regulator
AV942_06740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AV942_06745	COG0494	nUDIX hydrolase
AV942_06750	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AV942_06760	COG2255	four-way junction helicase activity
AV942_06765	COG0824	Thioesterase
AV942_06770	COG0811	peptide transport
AV942_06785	COG0823	Involved in the tonB-independent uptake of proteins
AV942_06790	COG2885	chlorophyll binding
AV942_06795	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AV942_06815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AV942_06835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AV942_06850	COG4667	esterase of the alpha-beta hydrolase superfamily
AV942_06855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AV942_06865	COG0784	Response regulator, receiver
AV942_06865	COG2205	protein histidine kinase activity
AV942_06885	COG3038	cytochrome b561
AV942_06905	COG0583	DNA-binding transcription factor activity
AV942_06910	COG1451	nucleotide metabolic process
AV942_06920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV942_06930	COG1309	transcriptional regulator
AV942_06935	COG4774	siderophore transport
AV942_06955	COG3706	GGDEF domain
AV942_06965	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV942_06965	COG3008	intermembrane lipid transfer
AV942_06970	COG2995	paraquat-inducible protein a
AV942_06985	COG0017	Asparaginyl-tRNA synthetase
AV942_07000	COG0189	ligase activity
AV942_07030	COG0156	8-amino-7-oxononanoate synthase activity
AV942_07035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV942_07045	COG3340	Belongs to the peptidase S51 family
AV942_07050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AV942_07055	COG4139	cobalamin transport
AV942_07060	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AV942_07065	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AV942_07080	COG5265	(ABC) transporter
AV942_07085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AV942_07095	COG0745	RESPONSE REGULATOR receiver
AV942_07120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV942_07160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV942_07175	COG2755	lipolytic protein G-D-S-L family
AV942_07180	COG4181	ATPase activity
AV942_07185	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AV942_07190	COG1090	epimerase
AV942_07195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV942_07200	COG0628	permease
AV942_07210	COG0745	RESPONSE REGULATOR receiver
AV942_07225	COG2350	Protein conserved in bacteria
AV942_07230	COG0159	tryptophan synthase activity
AV942_07240	COG0134	indole-3-glycerol-phosphate synthase activity
AV942_07240	COG0135	phosphoribosylanthranilate isomerase activity
AV942_07245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV942_07255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AV942_07260	COG0613	PHP domain protein
AV942_07265	COG0009	L-threonylcarbamoyladenylate synthase
AV942_07270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AV942_07275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AV942_07285	COG0656	L-ascorbic acid biosynthetic process
AV942_07290	COG0110	maltose O-acetyltransferase activity
AV942_07300	COG2733	membrane
AV942_07320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_07325	COG0500	methyltransferase
AV942_07330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV942_07335	COG0497	DNA recombination
AV942_07340	COG0783	Belongs to the Dps family
AV942_07350	COG1454	alcohol dehydrogenase
AV942_07355	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_07365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV942_07370	COG2610	gluconate transmembrane transporter activity
AV942_07375	COG4771	TonB-dependent receptor
AV942_07385	COG2205	protein histidine kinase activity
AV942_07385	COG2198	Histidine kinase
AV942_07385	COG0784	Response regulator, receiver
AV942_07390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AV942_07400	COG0484	heat shock protein binding
AV942_07405	COG3909	cytochrome
AV942_07410	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV942_07425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AV942_07430	COG0505	Belongs to the CarA family
AV942_07435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AV942_07440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV942_07460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV942_07465	COG0280	phosphate acetyltransferase
AV942_07465	COG0857	belongs to the CobB CobQ family
AV942_07480	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AV942_07485	COG4535	Mg2 and Co2 transporter CorC
AV942_07495	COG1702	phosphate starvation-inducible protein PhoH
AV942_07505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV942_07535	COG1607	acyl-coa hydrolase
AV942_07540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV942_07550	COG1115	amino acid carrier protein
AV942_07595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV942_07600	COG0012	GTP binding
AV942_07615	COG1064	alcohol dehydrogenase
AV942_07630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AV942_07640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AV942_07645	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AV942_07650	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AV942_07660	COG2890	protein-(glutamine-N5) methyltransferase activity
AV942_07665	COG0784	Response regulator, receiver
AV942_07665	COG3437	response regulator, receiver
AV942_07670	COG3094	Invasion gene expression up-regulator, SirB
AV942_07685	COG0583	DNA-binding transcription factor activity
AV942_07695	COG2363	Small membrane protein
AV942_07715	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AV942_07720	COG0515	serine threonine protein kinase
AV942_07725	COG2116	formate transmembrane transporter activity
AV942_07740	COG0714	Associated with various cellular activities
AV942_07745	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AV942_07750	COG0033	Phosphoglucomutase
AV942_07755	COG0058	SHG alpha-glucan phosphorylase activity
AV942_07765	COG2988	succinylglutamate desuccinylase activity
AV942_07800	COG1393	Belongs to the ArsC family
AV942_07825	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AV942_07855	COG5001	Diguanylate cyclase
AV942_07855	COG3300	MHYT domain
AV942_07880	COG2249	NAD(P)H dehydrogenase (quinone) activity
AV942_07900	COG1733	regulation of RNA biosynthetic process
AV942_07905	COG5002	protein histidine kinase activity
AV942_07905	COG3447	MASE1 domain protein
AV942_07905	COG5001	Diguanylate cyclase
AV942_07915	COG0402	S-adenosylhomocysteine deaminase activity
AV942_07920	COG2351	hydroxyisourate hydrolase activity
AV942_07935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV942_07950	COG1309	transcriptional regulator
AV942_07965	COG2252	PERMEase
AV942_07970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV942_07985	COG3706	GGDEF domain
AV942_07985	COG5001	Diguanylate cyclase
AV942_07985	COG4251	negative regulation of phosphorylation
AV942_07985	COG2203	Gaf domain
AV942_07990	COG2203	Gaf domain
AV942_07990	COG3706	GGDEF domain
AV942_07990	COG4251	negative regulation of phosphorylation
AV942_07990	COG5001	Diguanylate cyclase
AV942_07995	COG2205	protein histidine kinase activity
AV942_07995	COG0784	Response regulator, receiver
AV942_08010	COG2233	PERMEase
AV942_08025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV942_08030	COG0730	response to heat
AV942_08070	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_08085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AV942_08100	COG0662	Cupin 2, conserved barrel domain protein
AV942_08100	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AV942_08105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AV942_08115	COG1596	polysaccharide export
AV942_08120	COG0489	protein tyrosine kinase activity
AV942_08125	COG4464	protein tyrosine phosphatase activity
AV942_08180	COG1216	Glycosyl transferase, family 2
AV942_08195	COG1215	transferase activity, transferring glycosyl groups
AV942_08200	COG0438	transferase activity, transferring glycosyl groups
AV942_08210	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AV942_08230	COG0072	phenylalanine-tRNA ligase activity
AV942_08230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV942_08245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AV942_08255	COG1472	Belongs to the glycosyl hydrolase 3 family
AV942_08260	COG2096	Adenosyltransferase
AV942_08270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AV942_08280	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV942_08305	COG0708	Exodeoxyribonuclease III
AV942_08340	COG2814	Major facilitator Superfamily
AV942_08380	COG1024	Enoyl-CoA hydratase
AV942_08385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AV942_08390	COG1960	acyl-CoA dehydrogenase activity
AV942_08395	COG0789	Transcriptional regulator
AV942_08400	COG0183	Belongs to the thiolase family
AV942_08415	COG3706	GGDEF domain
AV942_08425	COG2925	Exonuclease
AV942_08430	COG0582	viral genome integration into host DNA
AV942_08470	COG1674	ftsk spoiiie
AV942_08470	COG0531	amino acid
AV942_08510	COG2197	response regulator
AV942_08525	COG3617	BRO family, N-terminal domain
AV942_08595	COG0305	Participates in initiation and elongation during chromosome replication
AV942_08685	COG3728	DNA packaging
AV942_08685	COG5484	DNA packaging
AV942_08830	COG1643	Atp-dependent helicase
AV942_08850	COG3321	synthase
AV942_08850	COG0604	alcohol dehydrogenase
AV942_08855	COG0328	RNA-DNA hybrid ribonuclease activity
AV942_08860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV942_08890	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV942_08900	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV942_08915	COG3724	N-succinylarginine dihydrolase activity
AV942_08925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AV942_08940	COG0746	molybdenum cofactor guanylyltransferase activity
AV942_08945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AV942_08950	COG0243	molybdopterin cofactor binding
AV942_08955	COG2153	protein acetylation
AV942_08970	COG1530	ribonuclease E activity
AV942_08985	COG0424	maF-like protein
AV942_08990	COG1399	metal-binding, possibly nucleic acid-binding protein
AV942_09000	COG0416	fatty acid biosynthetic process
AV942_09005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV942_09010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AV942_09020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV942_09025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV942_09035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AV942_09050	COG0084	hydrolase, TatD family'
AV942_09060	COG0702	epimerase
AV942_09065	COG0745	RESPONSE REGULATOR receiver
AV942_09065	COG3706	GGDEF domain
AV942_09085	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_09090	COG0596	Alpha beta hydrolase
AV942_09100	COG0183	Belongs to the thiolase family
AV942_09105	COG1960	acyl-CoA dehydrogenase activity
AV942_09125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV942_09135	COG0246	Mannitol dehydrogenase
AV942_09155	COG0668	transmembrane transport
AV942_09160	COG4771	TonB-dependent receptor
AV942_09180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV942_09180	COG2205	protein histidine kinase activity
AV942_09185	COG3437	response regulator, receiver
AV942_09195	COG0195	Participates in both transcription termination and antitermination
AV942_09210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AV942_09225	COG1187	pseudouridine synthase activity
AV942_09235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV942_09235	COG3153	acetyltransferase
AV942_09265	COG0450	alkyl hydroperoxide reductase
AV942_09310	COG1032	radical SAM domain protein
AV942_09325	COG4771	TonB-dependent receptor
AV942_09330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV942_09340	COG4134	Bacterial extracellular solute-binding protein
AV942_09350	COG4136	ATPase activity
AV942_09355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AV942_09380	COG5001	Diguanylate cyclase
AV942_09380	COG4251	negative regulation of phosphorylation
AV942_09380	COG2203	Gaf domain
AV942_09380	COG3706	GGDEF domain
AV942_09460	COG1902	pentaerythritol trinitrate reductase activity
AV942_09470	COG2867	negative regulation of translational initiation
AV942_09475	COG2914	Belongs to the UPF0125 (RnfH) family
AV942_09485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV942_09490	COG4771	TonB-dependent receptor
AV942_09495	COG0457	Tetratricopeptide repeat
AV942_09510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AV942_09510	COG0574	Belongs to the PEP-utilizing enzyme family
AV942_09545	COG2850	peptidyl-arginine hydroxylation
AV942_09555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AV942_09560	COG2915	High frequency lysogenization protein hflD homolog
AV942_09565	COG0482	sulfurtransferase activity
AV942_09570	COG1187	pseudouridine synthase activity
AV942_09580	COG1278	Cold shock
AV942_09585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AV942_09590	COG0542	response to heat
AV942_09595	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV942_09600	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AV942_09605	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AV942_09610	COG0492	ferredoxin-NADP+ reductase activity
AV942_09615	COG3092	negative regulation of chromosome organization
AV942_09620	COG3091	SprT-like family
AV942_09625	COG0616	signal peptide processing
AV942_09640	COG0778	Nitroreductase
AV942_09650	COG0252	asparaginase activity
AV942_09655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AV942_09660	COG0321	lipoyl(octanoyl) transferase activity
AV942_09665	COG2921	Belongs to the UPF0250 family
AV942_09670	COG1686	Belongs to the peptidase S11 family
AV942_09675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV942_09680	COG0772	Belongs to the SEDS family
AV942_09685	COG0768	penicillin binding
AV942_09690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AV942_09695	COG0799	negative regulation of ribosome biogenesis
AV942_09705	COG1466	dna polymerase III delta subunit
AV942_09710	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AV942_09715	COG0495	leucyl-tRNA aminoacylation
AV942_09730	COG1067	ATP-dependent peptidase activity
AV942_09735	COG0596	Alpha beta hydrolase
AV942_09740	COG3706	GGDEF domain
AV942_09750	COG1534	Rna-binding protein
AV942_09755	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AV942_09760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV942_09765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AV942_09770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV942_09775	COG0149	triose-phosphate isomerase activity
AV942_09780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV942_09790	COG5001	Diguanylate cyclase
AV942_09790	COG3300	MHYT domain
AV942_09805	COG1597	lipid kinase activity
AV942_09805	COG1803	Methylglyoxal synthase
AV942_09815	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_09820	COG0561	phosphatase activity
AV942_09835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV942_09860	COG1185	polyribonucleotide nucleotidyltransferase activity
AV942_09885	COG1819	glycosyl
AV942_10000	COG4372	Transposase
AV942_10030	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AV942_10035	COG1196	nuclear chromosome segregation
AV942_10045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AV942_10060	COG1132	(ABC) transporter
AV942_10065	COG1663	tetraacyldisaccharide 4'-kinase activity
AV942_10100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AV942_10105	COG0435	Glutathione S-transferase
AV942_10110	COG1741	Belongs to the pirin family
AV942_10115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV942_10125	COG0372	Belongs to the citrate synthase family
AV942_10130	COG2009	succinate dehydrogenase
AV942_10135	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AV942_10140	COG1053	succinate dehydrogenase
AV942_10145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AV942_10150	COG0567	Dehydrogenase, E1 component
AV942_10155	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV942_10190	COG4667	esterase of the alpha-beta hydrolase superfamily
AV942_10210	COG0366	Alpha amylase catalytic
AV942_10235	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_10240	COG2267	carboxylic ester hydrolase activity
AV942_10250	COG0616	signal peptide processing
AV942_10270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV942_10275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV942_10280	COG0386	Belongs to the glutathione peroxidase family
AV942_10285	COG2084	Dehydrogenase
AV942_10295	COG1960	acyl-CoA dehydrogenase activity
AV942_10300	COG1024	Enoyl-CoA hydratase
AV942_10305	COG2226	methyltransferase
AV942_10310	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV942_10315	COG3083	sulfuric ester hydrolase activity
AV942_10320	COG3082	Protein of unknown function (DUF1414)
AV942_10325	COG3081	Nucleoid-associated protein
AV942_10355	COG3275	phosphorelay sensor kinase activity
AV942_10360	COG3279	Response regulator of the LytR AlgR family
AV942_10365	COG0205	6-phosphofructokinase activity
AV942_10380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV942_10395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV942_10395	COG2205	protein histidine kinase activity
AV942_10415	COG0513	Belongs to the DEAD box helicase family
AV942_10425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AV942_10430	COG0583	DNA-binding transcription factor activity
AV942_10450	COG1760	l-serine dehydratase
AV942_10475	COG1322	Protein conserved in bacteria
AV942_10480	COG1404	Belongs to the peptidase S8 family
AV942_10485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AV942_10490	COG0022	dehydrogenase e1 component
AV942_10500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AV942_10505	COG0515	serine threonine protein kinase
AV942_10510	COG1946	Acyl-CoA thioesterase
AV942_10520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV942_10530	COG1956	GAF domain-containing protein
AV942_10545	COG0793	Belongs to the peptidase S41A family
AV942_10550	COG0733	neurotransmitter:sodium symporter activity
AV942_10560	COG0308	aminopeptidase N
AV942_10590	COG2902	Dehydrogenase
AV942_10595	COG0167	dihydroorotate dehydrogenase activity
AV942_10620	COG3130	regulation of translation
AV942_10625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV942_10635	COG0415	Belongs to the DNA photolyase family
AV942_10640	COG0415	Belongs to the DNA photolyase family
AV942_10645	COG0415	Belongs to the DNA photolyase family
AV942_10650	COG3046	protein related to deoxyribodipyrimidine photolyase
AV942_10660	COG4974	Belongs to the 'phage' integrase family
AV942_10670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV942_10675	COG0589	response to stress
AV942_10685	COG0069	glutamate synthase activity
AV942_10700	COG2193	ferroxidase activity
AV942_10710	COG3278	Belongs to the heme-copper respiratory oxidase family
AV942_10725	COG2010	Cytochrome c
AV942_10750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV942_10755	COG0589	response to stress
AV942_10760	COG0037	tRNA processing
AV942_10765	COG1752	Esterase of the alpha-beta hydrolase superfamily
AV942_10785	COG1280	lysine exporter protein (LysE YggA)
AV942_10790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AV942_10795	COG2897	thiosulfate sulfurtransferase activity
AV942_10800	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AV942_10830	COG0322	excinuclease ABC activity
AV942_10835	COG2197	response regulator
AV942_10840	COG0436	Aminotransferase
AV942_10860	COG2259	Doxx family
AV942_10865	COG0583	DNA-binding transcription factor activity
AV942_10880	COG0670	Belongs to the BI1 family
AV942_10885	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AV942_10900	COG2920	part of a sulfur-relay system
AV942_10930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AV942_10940	COG0531	amino acid
AV942_10940	COG1674	ftsk spoiiie
AV942_10950	COG0686	Belongs to the AlaDH PNT family
AV942_10955	COG0284	orotidine-5'-phosphate decarboxylase activity
AV942_10960	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AV942_10975	COG0776	regulation of translation
AV942_10980	COG0539	negative regulation of cytoplasmic translation
AV942_10985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AV942_10990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AV942_10995	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AV942_11005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV942_11010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV942_11015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV942_11020	COG0633	Ferredoxin
AV942_11050	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AV942_11055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV942_11065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AV942_11075	COG4783	chaperone-mediated protein folding
AV942_11085	COG1393	Belongs to the ArsC family
AV942_11100	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AV942_11115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AV942_11125	COG1960	acyl-CoA dehydrogenase activity
AV942_11150	COG0572	uridine kinase
AV942_11155	COG3769	mannosylglycerate metabolic process
AV942_11160	COG1215	transferase activity, transferring glycosyl groups
AV942_11165	COG0366	Alpha amylase catalytic
AV942_11175	COG0303	'Molybdopterin
AV942_11180	COG0534	Mate efflux family protein
AV942_11195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV942_11200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV942_11230	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AV942_11275	COG0405	Gamma-glutamyltransferase
AV942_11280	COG1024	Enoyl-CoA hydratase
AV942_11325	COG1448	Aminotransferase
AV942_11335	COG1671	Belongs to the UPF0178 family
AV942_11340	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_11345	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_11350	COG1960	acyl-CoA dehydrogenase activity
AV942_11355	COG0662	Cupin 2, conserved barrel domain protein
AV942_11355	COG2207	Transcriptional regulator
AV942_11370	COG1505	serine-type exopeptidase activity
AV942_11380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_11410	COG0596	Alpha beta hydrolase
AV942_11420	COG0716	FMN binding
AV942_11430	COG0735	belongs to the Fur family
AV942_11440	COG1984	allophanate hydrolase subunit 2
AV942_11445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AV942_11450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AV942_11455	COG2996	Protein conserved in bacteria
AV942_11460	COG1765	OsmC-like protein
AV942_11465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_11475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV942_11490	COG0436	Aminotransferase
AV942_11500	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV942_11510	COG2010	Cytochrome c
AV942_11510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV942_11515	COG2080	2 iron, 2 sulfur cluster binding
AV942_11540	COG1073	alpha beta
AV942_11545	COG2207	Transcriptional regulator
AV942_11560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AV942_11585	COG3012	SEC-C Motif Domain Protein
AV942_11590	COG0604	alcohol dehydrogenase
AV942_11600	COG1960	acyl-CoA dehydrogenase activity
AV942_11610	COG4771	TonB-dependent receptor
AV942_11630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV942_11635	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AV942_11655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AV942_11660	COG0315	cyclic pyranopterin monophosphate synthase activity
AV942_11665	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV942_11680	COG2161	toxin-antitoxin pair type II binding
AV942_11685	COG4115	mRNA cleavage
AV942_11700	COG0436	Aminotransferase
AV942_11705	COG3268	Saccharopine dehydrogenase
AV942_11710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV942_11725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AV942_11730	COG4206	TonB-dependent receptor
AV942_11740	COG5006	permease, DMT superfamily
AV942_11755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AV942_11760	COG1074	ATP-dependent DNA helicase activity
AV942_11765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AV942_11780	COG1022	Amp-dependent synthetase and ligase
AV942_11785	COG4251	negative regulation of phosphorylation
AV942_11785	COG3706	GGDEF domain
AV942_11785	COG5001	Diguanylate cyclase
AV942_11785	COG2203	Gaf domain
AV942_11805	COG0583	DNA-binding transcription factor activity
AV942_11820	COG0640	Transcriptional regulator
AV942_11840	COG2204	response regulator
AV942_11850	COG4251	negative regulation of phosphorylation
AV942_11855	COG0784	Response regulator, receiver
AV942_11860	COG2205	protein histidine kinase activity
AV942_11860	COG0784	Response regulator, receiver
AV942_11885	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV942_11905	COG3139	Protein of unknown function (DUF1315)
AV942_11920	COG1115	amino acid carrier protein
AV942_11925	COG2866	Carboxypeptidase
AV942_11945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AV942_11955	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV942_11960	COG1640	4-alpha-glucanotransferase
AV942_11965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AV942_11970	COG0676	glucose-6-phosphate 1-epimerase activity
AV942_11975	COG0800	Aldolase
AV942_11985	COG0129	dihydroxy-acid dehydratase activity
AV942_12000	COG1737	Transcriptional regulator
AV942_12005	COG0469	pyruvate kinase activity
AV942_12020	COG1960	acyl-CoA dehydrogenase activity
AV942_12040	COG0490	domain, Protein
AV942_12040	COG0471	metal ion transport
AV942_12060	COG0129	dihydroxy-acid dehydratase activity
AV942_12070	COG1737	Transcriptional regulator
AV942_12075	COG0469	pyruvate kinase activity
AV942_12080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV942_12100	COG2823	Periplasmic or secreted lipoprotein
AV942_12130	COG3665	Urea carboxylase-associated protein
AV942_12160	COG2356	endonuclease I
AV942_12165	COG0840	transmembrane signaling receptor activity
AV942_12180	COG0583	DNA-binding transcription factor activity
AV942_12185	COG1979	alcohol dehydrogenase
AV942_12190	COG5001	Diguanylate cyclase
AV942_12200	COG0784	Response regulator, receiver
AV942_12200	COG3437	response regulator, receiver
AV942_12205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV942_12205	COG4191	Histidine kinase
AV942_12285	COG0471	metal ion transport
AV942_12295	COG0489	protein tyrosine kinase activity
AV942_12300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV942_12300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV942_12305	COG0668	transmembrane transport
AV942_12310	COG2226	methyltransferase
AV942_12315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV942_12320	COG1388	LysM domain
AV942_12320	COG0741	lytic transglycosylase activity
AV942_12345	COG0215	cysteine-tRNA ligase activity
AV942_12350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV942_12355	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV942_12365	COG2268	Band 7 protein
AV942_12380	COG1733	regulation of RNA biosynthetic process
AV942_12385	COG0604	alcohol dehydrogenase
AV942_12390	COG0753	catalase activity
AV942_12395	COG0604	alcohol dehydrogenase
AV942_12400	COG0583	DNA-binding transcription factor activity
AV942_12435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AV942_12440	COG1286	toxin biosynthetic process
AV942_12445	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AV942_12450	COG0285	dihydrofolate synthase activity
AV942_12470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AV942_12475	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV942_12495	COG3609	addiction module antidote protein, CC2985 family
AV942_12505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV942_12510	COG0318	PFAM AMP-dependent synthetase and ligase
AV942_12520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV942_12520	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AV942_12555	COG0789	Transcriptional regulator
AV942_12560	COG0604	alcohol dehydrogenase
AV942_12585	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_12590	COG1119	ATPase activity
AV942_12595	COG2031	fatty acid transporter
AV942_12600	COG0784	Response regulator, receiver
AV942_12600	COG5002	protein histidine kinase activity
AV942_12600	COG2205	protein histidine kinase activity
AV942_12610	COG0612	Peptidase, M16
AV942_12625	COG3101	peptidyl-lysine hydroxylation
AV942_12655	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV942_12655	COG1902	pentaerythritol trinitrate reductase activity
AV942_12680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV942_12690	COG4399	Belongs to the UPF0754 family
AV942_12715	COG1770	oligopeptidase
AV942_12720	COG2186	Transcriptional regulator
AV942_12730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AV942_12735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV942_12745	COG2983	Belongs to the UPF0260 family
AV942_12750	COG0179	Fumarylacetoacetate (FAA) hydrolase
AV942_12765	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AV942_12770	COG0318	PFAM AMP-dependent synthetase and ligase
AV942_12775	COG2267	carboxylic ester hydrolase activity
AV942_12790	COG1214	PFAM Peptidase M22, glycoprotease
AV942_12795	COG1199	ATP-dependent helicase activity
AV942_12845	COG4771	TonB-dependent receptor
AV942_12855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AV942_12860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AV942_12865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV942_12870	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV942_12870	COG0131	Imidazoleglycerol-phosphate dehydratase
AV942_12875	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AV942_12890	COG0140	phosphoribosyl-ATP diphosphatase activity
AV942_12890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AV942_12905	COG2116	formate transmembrane transporter activity
AV942_12910	COG0612	Peptidase, M16
AV942_12940	COG0326	Molecular chaperone. Has ATPase activity
AV942_12945	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AV942_12965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV942_12970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AV942_12980	COG3220	belongs to the UPF0276 family
AV942_12990	COG0577	efflux transmembrane transporter activity
AV942_12990	COG1136	(ABC) transporter
AV942_13000	COG4251	negative regulation of phosphorylation
AV942_13000	COG5001	Diguanylate cyclase
AV942_13000	COG3706	GGDEF domain
AV942_13000	COG2203	Gaf domain
AV942_13025	COG1183	phosphatidylcholine synthase activity
AV942_13045	COG0277	FAD linked oxidase domain protein
AV942_13050	COG0542	response to heat
AV942_13060	COG0564	pseudouridine synthase activity
AV942_13075	COG1595	DNA-templated transcription, initiation
AV942_13090	COG4221	oxidoreductase activity
AV942_13105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AV942_13115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AV942_13125	COG0142	geranyltranstransferase activity
AV942_13135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AV942_13140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AV942_13150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AV942_13165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV942_13165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV942_13185	COG0488	(ABC) transporter
AV942_13195	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AV942_13205	COG0560	Phosphoserine phosphatase
AV942_13215	COG0084	hydrolase, TatD family'
AV942_13230	COG0571	ribonuclease III activity
AV942_13235	COG0681	Belongs to the peptidase S26 family
AV942_13260	COG1595	DNA-templated transcription, initiation
AV942_13265	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AV942_13280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AV942_13360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AV942_13365	COG1047	Peptidyl-prolyl cis-trans
AV942_13375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AV942_13380	COG0196	riboflavin kinase activity
AV942_13385	COG0728	peptidoglycan biosynthetic process
AV942_13390	COG0268	Binds directly to 16S ribosomal RNA
AV942_13410	COG0385	Bile acid
AV942_13435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV942_13440	COG0776	regulation of translation
AV942_13450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV942_13455	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AV942_13460	COG0740	serine-type endopeptidase activity
AV942_13465	COG0544	peptidyl-prolyl cis-trans isomerase activity
AV942_13510	COG1720	tRNA m6t6A37 methyltransferase activity
AV942_13520	COG1234	tRNA 3'-trailer cleavage
AV942_13530	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV942_13545	COG0517	IMP dehydrogenase activity
AV942_13545	COG0516	GMP reductase activity
AV942_13550	COG1570	exodeoxyribonuclease VII activity
AV942_13570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV942_13575	COG2976	Protein conserved in bacteria
AV942_13600	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AV942_13610	COG2166	iron-sulfur cluster assembly
AV942_13625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AV942_13630	COG0719	Fe-S assembly protein
AV942_13635	COG0396	ATPase activity
AV942_13640	COG0719	Fe-S assembly protein
AV942_13645	COG1104	cysteine desulfurase activity
AV942_13655	COG2072	flavoprotein involved in K transport
AV942_13660	COG1045	serine acetyltransferase
AV942_13665	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AV942_13670	COG0483	inositol monophosphate 1-phosphatase activity
AV942_13685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV942_13690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV942_13695	COG1862	Preprotein translocase
AV942_13700	COG0343	queuine tRNA-ribosyltransferase activity
AV942_13720	COG1842	Phage shock protein A
AV942_13725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AV942_13745	COG0754	glutathionylspermidine amidase activity
AV942_13775	COG2066	Belongs to the glutaminase family
AV942_13780	COG1785	Belongs to the alkaline phosphatase family
AV942_13840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV942_13860	COG0438	transferase activity, transferring glycosyl groups
AV942_13880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AV942_13885	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AV942_13915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AV942_13915	COG2755	lipolytic protein G-D-S-L family
AV942_13920	COG0367	asparagine synthase
AV942_13925	COG0438	transferase activity, transferring glycosyl groups
AV942_13935	COG2244	polysaccharide biosynthetic process
AV942_13965	COG0367	asparagine synthase
AV942_14000	COG0489	protein tyrosine kinase activity
AV942_14010	COG3409	Peptidoglycan-binding domain 1 protein
AV942_14010	COG3267	Type II secretory pathway component ExeA
AV942_14040	COG1560	Kdo2-lipid A biosynthetic process
AV942_14055	COG1960	acyl-CoA dehydrogenase activity
AV942_14070	COG5001	Diguanylate cyclase
AV942_14070	COG3300	MHYT domain
AV942_14075	COG1435	thymidine kinase activity
AV942_14085	COG1609	Transcriptional regulator
AV942_14090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AV942_14120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AV942_14125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV942_14130	COG1024	Enoyl-CoA hydratase
AV942_14130	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV942_14145	COG1012	belongs to the aldehyde dehydrogenase family
AV942_14165	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AV942_14190	COG1960	acyl-CoA dehydrogenase activity
AV942_14220	COG0745	RESPONSE REGULATOR receiver
AV942_14225	COG2205	protein histidine kinase activity
AV942_14265	COG2080	2 iron, 2 sulfur cluster binding
AV942_14270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AV942_14275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV942_14295	COG1028	Short-chain dehydrogenase reductase Sdr
AV942_14300	COG4221	oxidoreductase activity
AV942_14305	COG0693	protein deglycase activity
AV942_14310	COG1295	ribonuclease BN
AV942_14320	COG4681	YaeQ
AV942_14350	COG2814	Major facilitator Superfamily
AV942_14365	COG0514	ATP-dependent DNA helicase (RecQ)
AV942_14395	COG4251	negative regulation of phosphorylation
AV942_14400	COG2133	pyrroloquinoline quinone binding
AV942_14405	COG3609	addiction module antidote protein, CC2985 family
AV942_14435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV942_14440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV942_14455	COG0330	HflC and HflK could
AV942_14545	COG4772	TonB-dependent receptor
AV942_14590	COG4372	Transposase
AV942_14605	COG1017	nitric oxide dioxygenase activity
AV942_14605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV942_14610	COG3604	Transcriptional regulator
AV942_14640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AV942_14645	COG2971	BadF BadG BcrA BcrD
AV942_14650	COG0583	DNA-binding transcription factor activity
AV942_14655	COG1620	l-lactate permease
AV942_14675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV942_14680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV942_14685	COG0006	proline dipeptidase activity
AV942_14700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV942_14715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AV942_14720	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AV942_14725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV942_14745	COG3313	Fe-S protein
AV942_14780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV942_14785	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV942_14790	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AV942_14795	COG2186	Transcriptional regulator
AV942_14805	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV942_14810	COG3577	Aspartyl protease
AV942_14815	COG0157	Belongs to the NadC ModD family
AV942_14825	COG1459	type II secretion system
AV942_14830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AV942_14840	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AV942_14850	COG3608	succinylglutamate desuccinylase aspartoacylase
AV942_14855	COG0494	nUDIX hydrolase
AV942_14865	COG0739	heme binding
AV942_14870	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AV942_14875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AV942_14880	COG0849	cell division
AV942_14885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AV942_14890	COG1181	Belongs to the D-alanine--D-alanine ligase family
AV942_14895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV942_14905	COG0772	Belongs to the SEDS family
AV942_14910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AV942_14920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AV942_14925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV942_14930	COG0768	penicillin binding
AV942_14935	COG3116	cell division
AV942_14945	COG2001	Belongs to the MraZ family
AV942_14985	COG0678	peroxiredoxin activity
AV942_14985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV942_15000	COG3706	GGDEF domain
AV942_15010	COG2204	response regulator
AV942_15015	COG2205	protein histidine kinase activity
AV942_15015	COG0784	Response regulator, receiver
AV942_15040	COG0668	transmembrane transport
AV942_15045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AV942_15050	COG0189	ligase activity
AV942_15055	COG1678	Uncharacterized ACR, COG1678
AV942_15060	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AV942_15085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AV942_15090	COG0762	integral membrane protein
AV942_15100	COG1902	pentaerythritol trinitrate reductase activity
AV942_15100	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV942_15115	COG0625	glutathione transferase activity
AV942_15125	COG1764	response to oxidative stress
AV942_15130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV942_15145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AV942_15155	COG2814	Major facilitator Superfamily
AV942_15160	COG0724	RNA recognition motif
AV942_15185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AV942_15190	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AV942_15210	COG0583	DNA-binding transcription factor activity
AV942_15225	COG0640	Transcriptional regulator
AV942_15235	COG0431	NADPH-dependent FMN reductase
AV942_15240	COG0798	PFAM Bile acid sodium symporter
AV942_15245	COG2201	protein-glutamate methylesterase activity
AV942_15250	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AV942_15260	COG0642	Histidine kinase
AV942_15285	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV942_15310	COG1748	Saccharopine dehydrogenase
AV942_15325	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AV942_15330	COG3107	peptidoglycan biosynthetic process
AV942_15340	COG0438	transferase activity, transferring glycosyl groups
AV942_15350	COG2823	Periplasmic or secreted lipoprotein
AV942_15370	COG4585	Histidine kinase
AV942_15375	COG2197	response regulator
AV942_15390	COG4771	TonB-dependent receptor
AV942_15400	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AV942_15405	COG0372	Belongs to the citrate synthase family
AV942_15410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AV942_15415	COG2828	Protein conserved in bacteria
AV942_15420	COG2199	diguanylate cyclase activity
AV942_15420	COG2203	Gaf domain
AV942_15425	COG1940	carbohydrate kinase activity
AV942_15465	COG5002	protein histidine kinase activity
AV942_15465	COG2198	Histidine kinase
AV942_15465	COG0784	Response regulator, receiver
AV942_15470	COG3023	N-Acetylmuramoyl-L-alanine amidase
AV942_15475	COG0070	glutamate synthase
AV942_15475	COG0069	glutamate synthase activity
AV942_15475	COG0067	glutamate synthase
AV942_15480	COG0493	'glutamate synthase
AV942_15495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV942_15500	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AV942_15505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AV942_15510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV942_15525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV942_15530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AV942_15535	COG4942	peptidase
AV942_15540	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AV942_15545	COG0738	Major facilitator superfamily
AV942_15555	COG1902	pentaerythritol trinitrate reductase activity
AV942_15575	COG0625	glutathione transferase activity
AV942_15600	COG2894	cell division
AV942_15605	COG0850	regulation of cytokinetic process
AV942_15615	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AV942_15645	COG1914	H( )-stimulated, divalent metal cation uptake system
AV942_15650	COG0436	Aminotransferase
AV942_15665	COG0174	glutamine synthetase
AV942_15675	COG3852	Histidine kinase
AV942_15680	COG2204	response regulator
AV942_15685	COG3437	response regulator, receiver
AV942_15690	COG0204	Acyl-transferase
AV942_15710	COG3920	Histidine kinase
AV942_15710	COG2202	Pas domain
AV942_15730	COG2205	protein histidine kinase activity
AV942_15730	COG3437	response regulator, receiver
AV942_15730	COG3850	Histidine kinase
AV942_15730	COG4999	Histidine kinase
AV942_15735	COG0525	valine-tRNA ligase activity
AV942_15740	COG2927	DNA polymerase III (CHI subunit)
AV942_15745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV942_15750	COG0795	lipopolysaccharide-transporting ATPase activity
AV942_15755	COG0795	lipopolysaccharide-transporting ATPase activity
AV942_15850	COG4974	Belongs to the 'phage' integrase family
AV942_15865	COG2856	Zn peptidase
AV942_15955	COG3250	beta-galactosidase activity
AV942_15965	COG4948	Mandelate Racemase Muconate Lactonizing
AV942_15970	COG3661	Belongs to the glycosyl hydrolase 67 family
AV942_15985	COG2203	Gaf domain
AV942_15985	COG2199	diguanylate cyclase activity
AV942_16015	COG0673	inositol 2-dehydrogenase activity
AV942_16025	COG0628	permease
AV942_16040	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AV942_16045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV942_16050	COG4558	Periplasmic binding protein
AV942_16060	COG4206	TonB-dependent receptor
AV942_16070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AV942_16075	COG0697	spore germination
AV942_16100	COG1971	Probably functions as a manganese efflux pump
AV942_16110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AV942_16125	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AV942_16135	COG0679	Auxin Efflux Carrier
AV942_16165	COG1131	(ABC) transporter
AV942_16175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV942_16185	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AV942_16225	COG2205	protein histidine kinase activity
AV942_16235	COG0348	domain, Protein
AV942_16235	COG3901	Regulator of nitric oxide reductase transcription
AV942_16245	COG2197	response regulator
AV942_16270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV942_16285	COG4771	TonB-dependent receptor
AV942_16295	COG0583	DNA-binding transcription factor activity
AV942_16300	COG1304	FMN binding
AV942_16305	COG0277	FAD linked oxidase domain protein
AV942_16315	COG1462	curli production assembly transport component CsgG
AV942_16345	COG2197	response regulator
AV942_16360	COG0513	Belongs to the DEAD box helicase family
AV942_16365	COG1294	oxidase, subunit
AV942_16370	COG1271	oxidase subunit
AV942_16390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV942_16400	COG2124	cytochrome p450
AV942_16420	COG2199	diguanylate cyclase activity
AV942_16420	COG2203	Gaf domain
AV942_16465	COG2337	Toxic component of a toxin-antitoxin (TA) module
AV942_16495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV942_16530	COG3264	Mechanosensitive ion channel
AV942_16530	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AV942_16570	COG0730	response to heat
AV942_16590	COG4191	Histidine kinase
AV942_16600	COG0417	DNA replication proofreading
AV942_16610	COG0318	PFAM AMP-dependent synthetase and ligase
AV942_16645	COG1309	transcriptional regulator
AV942_16655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV942_16665	COG1573	uracil-dna glycosylase
AV942_16670	COG3300	MHYT domain
AV942_16670	COG5001	Diguanylate cyclase
AV942_16690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV942_16710	COG1983	PspC domain protein
AV942_16715	COG1842	Phage shock protein A
AV942_16725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV942_16745	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AV942_16745	COG2885	chlorophyll binding
AV942_16750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV942_16760	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AV942_16765	COG0204	Acyl-transferase
AV942_16770	COG0204	Acyl-transferase
AV942_16775	COG0668	transmembrane transport
AV942_16790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AV942_16795	COG0733	neurotransmitter:sodium symporter activity
AV942_16810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV942_16825	COG0716	FMN binding
AV942_16835	COG0848	biopolymer transport protein
AV942_16850	COG0457	Tetratricopeptide repeat
AV942_16855	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AV942_16865	COG1215	transferase activity, transferring glycosyl groups
AV942_16880	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AV942_16885	COG0702	epimerase
AV942_16900	COG5001	Diguanylate cyclase
AV942_16900	COG5002	protein histidine kinase activity
AV942_16915	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AV942_16925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV942_16935	COG0583	DNA-binding transcription factor activity
AV942_16940	COG0121	glutamine amidotransferase
AV942_16945	COG4682	membrane
AV942_16965	COG1953	Uracil, thiamine, allantoin
AV942_16970	COG4771	TonB-dependent receptor
AV942_16980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV942_16985	COG0778	Nitroreductase
AV942_16990	COG0596	Alpha beta hydrolase
AV942_16995	COG0251	oxidation-reduction process
AV942_17000	COG1335	isochorismatase
AV942_17005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV942_17010	COG1309	transcriptional regulator
AV942_17025	COG4628	conserved protein (DUF2132)
AV942_17030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV942_17040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AV942_17050	COG1477	protein flavinylation
AV942_17055	COG2871	sodium ion transport
AV942_17060	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV942_17065	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV942_17070	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV942_17075	COG1805	sodium ion transport
AV942_17080	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV942_17085	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AV942_17090	COG0545	Peptidyl-prolyl cis-trans isomerase
AV942_17095	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AV942_17100	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AV942_17115	COG0039	L-malate dehydrogenase activity
AV942_17120	COG1438	arginine binding
AV942_17145	COG0572	uridine kinase
AV942_17150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AV942_17170	COG3706	GGDEF domain
AV942_17170	COG0745	RESPONSE REGULATOR receiver
AV942_17175	COG2176	DNA-directed DNA polymerase activity
AV942_17180	COG0517	IMP dehydrogenase activity
AV942_17180	COG1125	glycine betaine transport
AV942_17185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV942_17195	COG2205	protein histidine kinase activity
AV942_17205	COG0189	ligase activity
AV942_17215	COG0189	ligase activity
AV942_17215	COG4067	protein conserved in archaea
AV942_17240	COG1283	sodium-dependent phosphate transmembrane transporter activity
AV942_17245	COG0667	Aldo Keto reductase
AV942_17265	COG5001	Diguanylate cyclase
AV942_17295	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AV942_17305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AV942_17345	COG2274	protein secretion by the type I secretion system
AV942_17350	COG0583	DNA-binding transcription factor activity
AV942_17375	COG0438	transferase activity, transferring glycosyl groups
AV942_17375	COG1216	Glycosyl transferase, family 2
AV942_17415	COG0457	Tetratricopeptide repeat
AV942_17450	COG1216	Glycosyl transferase, family 2
AV942_17450	COG0463	Glycosyl transferase, family 2
AV942_17550	COG4372	Transposase
AV942_17600	COG2161	toxin-antitoxin pair type II binding
AV942_17610	COG0202	RNA polymerase activity
AV942_17635	COG0201	protein transport
AV942_17655	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AV942_17690	COG0784	Response regulator, receiver
AV942_17690	COG5002	protein histidine kinase activity
AV942_17715	COG0557	exoribonuclease II activity
AV942_17760	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AV942_17775	COG0543	2 iron, 2 sulfur cluster binding
AV942_17790	COG2234	aminopeptidase activity
AV942_17800	COG4251	negative regulation of phosphorylation
AV942_17810	COG1271	oxidase subunit
AV942_17815	COG1294	oxidase, subunit
AV942_17820	COG1522	sequence-specific DNA binding
AV942_17830	COG1278	Cold shock
AV942_17835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV942_17855	COG0339	signal peptide processing
AV942_17860	COG2201	protein-glutamate methylesterase activity
AV942_17870	COG3852	Histidine kinase
AV942_17880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV942_17885	COG0243	molybdopterin cofactor binding
AV942_17890	COG0823	Involved in the tonB-independent uptake of proteins
AV942_17890	COG1506	peptidase
AV942_17890	COG4946	Tricorn protease homolog
AV942_17935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV942_17945	COG2197	response regulator
AV942_17955	COG0189	ligase activity
AV942_17975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AV942_17980	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV942_17985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AV942_18000	COG0281	malic enzyme
AV942_18010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AV942_18040	COG0456	acetyltransferase
AV942_18050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV942_18055	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV942_18060	COG2177	Part of the ABC transporter FtsEX involved in
AV942_18065	COG2884	Cell division ATP-binding protein ftsE
AV942_18070	COG0552	protein localization to endoplasmic reticulum
AV942_18075	COG0742	ribosomal rna small subunit methyltransferase
AV942_18085	COG2095	MarC family integral membrane protein
AV942_18105	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AV942_18110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV942_18115	COG0617	tRNA 3'-terminal CCA addition
AV942_18120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AV942_18135	COG0076	glutamate decarboxylase activity
AV942_18150	COG0842	Transport permease protein
AV942_18155	COG1131	(ABC) transporter
AV942_18160	COG0745	RESPONSE REGULATOR receiver
AV942_18165	COG2205	protein histidine kinase activity
AV942_18170	COG4774	siderophore transport
AV942_18190	COG1253	flavin adenine dinucleotide binding
AV942_18200	COG1966	Carbon starvation protein
AV942_18225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV942_18230	COG0049	tRNA binding
AV942_18235	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AV942_18240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AV942_18245	COG0085	RNA polymerase activity
AV942_18250	COG0222	ribosome binding
AV942_18255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AV942_18260	COG0081	regulation of translation
AV942_18265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AV942_18285	COG0250	Participates in transcription elongation, termination and antitermination
AV942_18290	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV942_18300	COG1132	(ABC) transporter
AV942_18305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AV942_18310	COG3590	peptidase
AV942_18320	COG0513	Belongs to the DEAD box helicase family
AV942_18325	COG0418	dihydroorotase activity
AV942_18330	COG3040	lipid binding
AV942_18335	COG4989	oxidoreductase activity
AV942_18340	COG0346	lactoylglutathione lyase activity
AV942_18345	COG0668	transmembrane transport
AV942_18365	COG0302	gtp cyclohydrolase
AV942_18375	COG2957	Belongs to the agmatine deiminase family
AV942_18380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV942_18395	COG1201	RNA secondary structure unwinding
AV942_18405	COG1793	dna ligase
AV942_18410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV942_18415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV942_18425	COG0646	methionine synthase
AV942_18425	COG1410	methionine synthase
AV942_18430	COG0625	glutathione transferase activity
AV942_18435	COG0625	glutathione transferase activity
AV942_18445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AV942_18460	COG1012	belongs to the aldehyde dehydrogenase family
AV942_18465	COG0028	Belongs to the TPP enzyme family
AV942_18475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AV942_18480	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AV942_18485	COG0330	HflC and HflK could
AV942_18490	COG0330	HflC and HflK could
AV942_18495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AV942_18500	COG1923	regulation of RNA biosynthetic process
AV942_18505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AV942_18520	COG0802	atpase or kinase
AV942_18525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AV942_18525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AV942_18530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AV942_18540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AV942_18550	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AV942_18555	COG0735	belongs to the Fur family
AV942_18565	COG0432	Pfam Uncharacterised protein family UPF0047
AV942_18575	COG0305	Participates in initiation and elongation during chromosome replication
AV942_18600	COG2258	MOSC domain
AV942_18630	COG2205	protein histidine kinase activity
AV942_18650	COG0840	transmembrane signaling receptor activity
AV942_18655	COG5002	protein histidine kinase activity
AV942_18660	COG0840	transmembrane signaling receptor activity
AV942_18690	COG1472	Belongs to the glycosyl hydrolase 3 family
AV942_18700	COG2723	6-phospho-beta-galactosidase activity
AV942_18705	COG1609	Transcriptional regulator
AV942_18710	COG2814	Major facilitator Superfamily
AV942_18710	COG0477	Major facilitator Superfamily
AV942_18715	COG4319	ketosteroid isomerase
AV942_18735	COG2375	cellular response to nickel ion
AV942_18740	COG3237	CsbD-like
AV942_18770	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV942_18770	COG0596	Alpha beta hydrolase
AV942_18790	COG3038	cytochrome b561
AV942_18800	COG1252	NADH dehydrogenase
AV942_18815	COG0583	DNA-binding transcription factor activity
AV942_18820	COG2067	long-chain fatty acid transport protein
AV942_18825	COG2130	NADP-dependent
AV942_18830	COG5001	Diguanylate cyclase
AV942_18830	COG2203	Gaf domain
AV942_18830	COG4251	negative regulation of phosphorylation
AV942_18830	COG3706	GGDEF domain
AV942_18835	COG0784	Response regulator, receiver
AV942_18835	COG2205	protein histidine kinase activity
AV942_18845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV942_18850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AV942_18855	COG1349	DNA-binding transcription factor activity
AV942_18860	COG0673	inositol 2-dehydrogenase activity
AV942_18875	COG0697	spore germination
AV942_18880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV942_18885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AV942_18890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AV942_18895	COG1166	arginine decarboxylase activity
AV942_18905	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AV942_18910	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV942_18915	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV942_18985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV942_18990	COG0109	protoheme IX farnesyltransferase activity
AV942_19010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV942_19055	COG3030	protein affecting phage T7 exclusion by the F plasmid
AV942_19060	COG1324	tolerance protein
AV942_19065	COG4232	protein-disulfide reductase activity
AV942_19070	COG0739	heme binding
AV942_19075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AV942_19080	COG0511	ligase activity, forming carbon-carbon bonds
AV942_19085	COG0439	Biotin carboxylase
AV942_19130	COG0154	amidase activity
AV942_19145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV942_19150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AV942_19165	COG0151	Belongs to the GarS family
AV942_19180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV942_19185	COG3954	Phosphoribulokinase
AV942_19195	COG0745	RESPONSE REGULATOR receiver
AV942_19210	COG1501	Belongs to the glycosyl hydrolase 31 family
AV942_19220	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AV942_19230	COG3031	protein transport across the cell outer membrane
AV942_19240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV942_19245	COG1459	type II secretion system
AV942_19250	COG2165	general secretion pathway protein
AV942_19255	COG2165	general secretion pathway protein
AV942_19265	COG4795	General secretion pathway protein
AV942_19280	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AV942_19295	COG1012	belongs to the aldehyde dehydrogenase family
AV942_19305	COG1011	Hydrolase
AV942_19310	COG0494	nUDIX hydrolase
AV942_19315	COG1218	3'(2'),5'-bisphosphate nucleotidase
AV942_19330	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AV942_19340	COG3089	Belongs to the UPF0270 family
AV942_19345	COG0429	hydrolase of the alpha beta-hydrolase fold
AV942_19355	COG0488	(ABC) transporter
AV942_19370	COG2900	Belongs to the SlyX family
AV942_19380	COG0545	Peptidyl-prolyl cis-trans isomerase
AV942_19390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV942_19395	COG2183	response to ionizing radiation
AV942_19420	COG2207	Transcriptional regulator
AV942_19420	COG1609	Transcriptional regulator
AV942_19425	COG2211	Major facilitator Superfamily
AV942_19440	COG3693	PFAM glycoside hydrolase, family 10
AV942_19445	COG0667	Aldo Keto reductase
AV942_19450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV942_19455	COG2115	Belongs to the xylose isomerase family
AV942_19460	COG1070	Carbohydrate kinase
AV942_19475	COG1472	Belongs to the glycosyl hydrolase 3 family
AV942_19480	COG0477	Major facilitator Superfamily
AV942_19525	COG0596	Alpha beta hydrolase
AV942_19530	COG1040	competence protein
AV942_19550	COG1794	racemase activity, acting on amino acids and derivatives
AV942_19560	COG0534	Mate efflux family protein
AV942_19575	COG1999	signal sequence binding
AV942_19580	COG0109	protoheme IX farnesyltransferase activity
AV942_19585	COG1612	heme a metabolic process
AV942_19605	COG1845	cytochrome c oxidase, subunit III
AV942_19610	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AV942_19615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV942_19620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV942_19640	COG0129	dihydroxy-acid dehydratase activity
AV942_19650	COG0606	chelatase, subunit chli
AV942_19655	COG0583	DNA-binding transcription factor activity
AV942_19665	COG2814	Major facilitator Superfamily
AV942_19675	COG0729	surface antigen
AV942_19680	COG2911	Protein conserved in bacteria
AV942_19705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV942_19715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV942_19735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV942_19760	COG1228	amidohydrolase
AV942_19785	COG0425	Belongs to the sulfur carrier protein TusA family
AV942_19800	COG1561	YicC-like family, N-terminal region
AV942_19810	COG3550	peptidyl-serine autophosphorylation
AV942_19815	COG3620	sequence-specific DNA binding
AV942_19880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV942_19910	COG5433	transposase activity
AV942_19915	COG3119	arylsulfatase activity
AV942_19920	COG0714	Associated with various cellular activities
AV942_19935	COG2304	oxidoreductase activity
AV942_19970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AV942_19980	COG1960	acyl-CoA dehydrogenase activity
AV942_19990	COG1024	Enoyl-CoA hydratase
AV942_20000	COG2801	Transposase and inactivated derivatives
AV942_20035	COG3177	Filamentation induced by cAMP protein fic
AV942_20045	COG1609	Transcriptional regulator
AV942_20060	COG2199	diguanylate cyclase activity
AV942_20060	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AV942_20085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AV942_20105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AV942_20110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AV942_20130	COG1475	DNA binding
AV942_20135	COG1192	Involved in chromosome partitioning
AV942_20160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV942_20165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AV942_20175	COG0706	membrane insertase activity
AV942_20180	COG0594	ribonuclease P activity
AV942_20185	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AV942_20720	COG1132	(ABC) transporter
AV942_20740	COG2801	Transposase and inactivated derivatives
AV942_20820	COG2201	protein-glutamate methylesterase activity
AV942_20860	COG5290	Psort location Cytoplasmic, score
AV942_20890	COG3209	COG3209 Rhs family protein
AV942_20900	COG3209	COG3209 Rhs family protein
AV942_21025	COG5310	Homospermidine synthase
AV942_21050	COG3251	PFAM MbtH domain protein
AV942_21220	COG0210	DNA helicase
AV942_21260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV942_21290	COG4584	PFAM Integrase catalytic
AV942_21295	COG1484	DNA-dependent DNA replication
AV942_21310	COG5001	Diguanylate cyclase
AV942_21310	COG3300	MHYT domain
AV942_21325	COG3706	GGDEF domain
AV942_21410	COG1192	Involved in chromosome partitioning