AD45P2_00590 119d2661efb0e6c497c76203662ce30d 197 SUPERFAMILY SSF52096 17 179 3.32E-24 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AD45P2_00590 119d2661efb0e6c497c76203662ce30d 197 Gene3D G3DSA:3.90.226.10 28 185 1.4E-25 T 30-10-2018 AD45P2_00590 119d2661efb0e6c497c76203662ce30d 197 Pfam PF00574 Clp protease 51 179 2.0E-14 T 30-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AD45P2_00485 a4aaeea11f5d5eff2859e216950839e2 376 Gene3D G3DSA:3.30.470.30 131 238 3.5E-28 T 30-10-2018 AD45P2_00485 a4aaeea11f5d5eff2859e216950839e2 376 Gene3D G3DSA:3.30.1490.70 106 285 3.5E-28 T 30-10-2018 AD45P2_00485 a4aaeea11f5d5eff2859e216950839e2 376 SUPERFAMILY SSF50249 260 373 2.91E-14 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold AD45P2_00485 a4aaeea11f5d5eff2859e216950839e2 376 SUPERFAMILY SSF56091 105 287 3.84E-27 T 30-10-2018 AD45P2_00485 a4aaeea11f5d5eff2859e216950839e2 376 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 126 134 - T 30-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 AD45P2_00485 a4aaeea11f5d5eff2859e216950839e2 376 Pfam PF01068 ATP dependent DNA ligase domain 107 287 7.9E-16 T 30-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AD45P2_00455 b5ed6fb83935f51e242fc6b04fedfeac 178 SUPERFAMILY SSF69796 2 65 3.92E-7 T 30-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 AD45P2_00455 b5ed6fb83935f51e242fc6b04fedfeac 178 Pfam PF02511 Thymidylate synthase complementing protein 5 67 2.5E-8 T 30-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 AD45P2_00455 b5ed6fb83935f51e242fc6b04fedfeac 178 Gene3D G3DSA:3.30.1360.170 1 75 2.3E-11 T 30-10-2018 AD45P2_00345 8c4688a473b96492bf0cf280d5259216 149 Gene3D G3DSA:1.10.10.10 2 76 3.7E-15 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AD45P2_00345 8c4688a473b96492bf0cf280d5259216 149 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 47 59 8.5E-10 T 30-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AD45P2_00345 8c4688a473b96492bf0cf280d5259216 149 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 17 31 8.5E-10 T 30-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AD45P2_00345 8c4688a473b96492bf0cf280d5259216 149 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 31 47 8.5E-10 T 30-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AD45P2_00345 8c4688a473b96492bf0cf280d5259216 149 SMART SM00421 14 71 8.2E-11 T 30-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AD45P2_00345 8c4688a473b96492bf0cf280d5259216 149 SUPERFAMILY SSF46894 13 72 6.46E-14 T 30-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AD45P2_00345 8c4688a473b96492bf0cf280d5259216 149 Pfam PF00196 Bacterial regulatory proteins, luxR family 17 69 5.6E-12 T 30-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AD45P2_00475 45424c25ef370d08ae51fddec439c013 284 Gene3D G3DSA:3.30.479.30 50 185 2.9E-6 T 30-10-2018 AD45P2_00475 45424c25ef370d08ae51fddec439c013 284 Pfam PF01145 SPFH domain / Band 7 family 26 200 9.7E-23 T 30-10-2018 IPR001107 Band 7 domain AD45P2_00475 45424c25ef370d08ae51fddec439c013 284 SMART SM00244 22 184 4.3E-8 T 30-10-2018 IPR001107 Band 7 domain AD45P2_00475 45424c25ef370d08ae51fddec439c013 284 SUPERFAMILY SSF117892 54 187 5.1E-11 T 30-10-2018 IPR036013 Band 7/SPFH domain superfamily AD45P2_00560 e708305933a3ac2f8a4ed11feb9e9d9a 223 Pfam PF01612 3'-5' exonuclease 81 213 1.6E-9 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AD45P2_00560 e708305933a3ac2f8a4ed11feb9e9d9a 223 SUPERFAMILY SSF53098 48 213 2.0E-13 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily AD45P2_00560 e708305933a3ac2f8a4ed11feb9e9d9a 223 Gene3D G3DSA:3.30.420.10 17 220 3.5E-15 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AD45P2_00575 e2a0cb330ffa79ef9d0edcb0685fd8e4 573 PRINTS PR01183 Ribonucleotide reductase large chain signature 384 411 7.9E-22 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AD45P2_00575 e2a0cb330ffa79ef9d0edcb0685fd8e4 573 PRINTS PR01183 Ribonucleotide reductase large chain signature 140 159 7.9E-22 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AD45P2_00575 e2a0cb330ffa79ef9d0edcb0685fd8e4 573 PRINTS PR01183 Ribonucleotide reductase large chain signature 323 345 7.9E-22 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AD45P2_00575 e2a0cb330ffa79ef9d0edcb0685fd8e4 573 Gene3D G3DSA:3.20.70.20 2 547 1.7E-139 T 30-10-2018 AD45P2_00575 e2a0cb330ffa79ef9d0edcb0685fd8e4 573 SUPERFAMILY SSF51998 71 540 4.27E-119 T 30-10-2018 AD45P2_00575 e2a0cb330ffa79ef9d0edcb0685fd8e4 573 Pfam PF02867 Ribonucleotide reductase, barrel domain 73 378 7.4E-63 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AD45P2_00575 e2a0cb330ffa79ef9d0edcb0685fd8e4 573 Pfam PF02867 Ribonucleotide reductase, barrel domain 380 522 1.8E-26 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AD45P2_00125 f61e5b94a7ae0dd13244ac03704a6205 128 SMART SM00974 28 119 5.4E-5 T 30-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding AD45P2_00125 f61e5b94a7ae0dd13244ac03704a6205 128 Pfam PF10544 T5orf172 domain 19 117 1.1E-11 T 30-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding AD45P2_00565 358ca51ac3113879d6e482990305b976 611 PRINTS PR00868 DNA-polymerase family A (pol I) signature 534 547 3.7E-10 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 PRINTS PR00868 DNA-polymerase family A (pol I) signature 294 316 3.7E-10 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 PRINTS PR00868 DNA-polymerase family A (pol I) signature 340 363 3.7E-10 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 PRINTS PR00868 DNA-polymerase family A (pol I) signature 370 383 3.7E-10 T 30-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 SMART SM00482 326 551 1.2E-8 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 Pfam PF00476 DNA polymerase family A 212 588 2.7E-32 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 SUPERFAMILY SSF56672 32 590 2.89E-52 T 30-10-2018 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 Gene3D G3DSA:3.30.70.370 302 587 4.1E-37 T 30-10-2018 AD45P2_00565 358ca51ac3113879d6e482990305b976 611 Gene3D G3DSA:1.10.150.20 349 514 4.1E-37 T 30-10-2018 AD45P2_00465 d4ad87b9c577a57f9d0f4a7d1ba5e68a 155 SUPERFAMILY SSF82771 2 89 3.01E-12 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AD45P2_00465 d4ad87b9c577a57f9d0f4a7d1ba5e68a 155 SMART SM00465 3 92 8.0E-5 T 30-10-2018 IPR000305 GIY-YIG endonuclease AD45P2_00465 d4ad87b9c577a57f9d0f4a7d1ba5e68a 155 SUPERFAMILY SSF64496 98 148 4.45E-8 T 30-10-2018 AD45P2_00465 d4ad87b9c577a57f9d0f4a7d1ba5e68a 155 Gene3D G3DSA:3.40.1440.10 2 99 1.4E-10 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AD45P2_00465 d4ad87b9c577a57f9d0f4a7d1ba5e68a 155 Pfam PF01541 GIY-YIG catalytic domain 5 87 1.0E-8 T 30-10-2018 IPR000305 GIY-YIG endonuclease AD45P2_00470 f73553dc240cf3774720034937ce23d7 138 SUPERFAMILY SSF69796 5 124 6.02E-19 T 30-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 AD45P2_00470 f73553dc240cf3774720034937ce23d7 138 Gene3D G3DSA:3.30.1360.170 1 136 2.5E-25 T 30-10-2018 AD45P2_00470 f73553dc240cf3774720034937ce23d7 138 Pfam PF02511 Thymidylate synthase complementing protein 5 126 4.1E-19 T 30-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 AD45P2_00520 1839664f81d701b6f486f6ff93931919 268 SUPERFAMILY SSF52980 47 175 3.22E-6 T 30-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AD45P2_00520 1839664f81d701b6f486f6ff93931919 268 Gene3D G3DSA:3.90.320.10 12 200 1.4E-6 T 30-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AD45P2_00520 1839664f81d701b6f486f6ff93931919 268 Pfam PF12705 PD-(D/E)XK nuclease superfamily 20 220 2.3E-8 T 30-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AD45P2_00110 5121f69571037478c3441d93fcaeb78e 520 Gene3D G3DSA:3.40.50.300 23 219 7.0E-10 T 30-10-2018 AD45P2_00510 aab71bd31d5a1d532c4f246630794dda 695 SUPERFAMILY SSF55874 29 152 4.79E-13 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AD45P2_00510 aab71bd31d5a1d532c4f246630794dda 695 Gene3D G3DSA:3.30.565.10 2 200 1.5E-15 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AD45P2_00510 aab71bd31d5a1d532c4f246630794dda 695 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 49 148 3.0E-7 T 30-10-2018 AD45P2_00135 d22ba53d3e7189ae736f0697c35902f5 231 SUPERFAMILY SSF110849 4 71 4.88E-8 T 30-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AD45P2_00135 d22ba53d3e7189ae736f0697c35902f5 231 Pfam PF02195 ParB-like nuclease domain 6 53 3.7E-6 T 30-10-2018 IPR003115 ParB/Sulfiredoxin AD45P2_00555 b619ec103440e42ea76c46b21b02be54 475 Gene3D G3DSA:3.40.50.300 287 474 1.7E-12 T 30-10-2018 AD45P2_00555 b619ec103440e42ea76c46b21b02be54 475 Pfam PF13361 UvrD-like helicase C-terminal domain 287 466 2.0E-9 T 30-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AD45P2_00555 b619ec103440e42ea76c46b21b02be54 475 Pfam PF13245 AAA domain 18 219 3.0E-10 T 30-10-2018 AD45P2_00555 b619ec103440e42ea76c46b21b02be54 475 SUPERFAMILY SSF52540 2 462 5.75E-38 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AD45P2_00095 adabe3a9c351634ffc11886c7074f5f2 1545 Pfam PF13884 Chaperone of endosialidase 1443 1493 6.2E-13 T 30-10-2018 IPR030392 Intramolecular chaperone auto-processing domain AD45P2_00255 9add1c87fd084f93e7005510f968555c 440 Pfam PF13203 Putative metallopeptidase domain 58 284 3.4E-20 T 30-10-2018 IPR025154 Putative metallopeptidase domain AD45P2_00255 9add1c87fd084f93e7005510f968555c 440 Pfam PF09967 VWA-like domain (DUF2201) 308 417 2.2E-10 T 30-10-2018 IPR018698 VWA-like domain AD45P2_00580 edfd2211abf34f4e034203af2fb17ab3 309 Pfam PF00268 Ribonucleotide reductase, small chain 8 274 2.3E-58 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AD45P2_00580 edfd2211abf34f4e034203af2fb17ab3 309 Gene3D G3DSA:1.10.620.20 2 299 3.5E-76 T 30-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 AD45P2_00580 edfd2211abf34f4e034203af2fb17ab3 309 SUPERFAMILY SSF47240 8 304 2.2E-68 T 30-10-2018 IPR009078 Ferritin-like superfamily AD45P2_00435 3bf2157e30249872bef9763dc08df382 194 Gene3D G3DSA:3.40.50.300 1 188 8.2E-19 T 30-10-2018 AD45P2_00460 a18b47722c9d9f104208a041c72087f5 221 SUPERFAMILY SSF54060 43 135 2.82E-8 T 30-10-2018 AD45P2_00460 a18b47722c9d9f104208a041c72087f5 221 Pfam PF13392 HNH endonuclease 87 132 1.8E-9 T 30-10-2018 IPR003615 HNH nuclease AD45P2_00500 ed1f3f472e5d7a83f8d0f77a79ba7dd3 81 Gene3D G3DSA:3.40.30.10 1 80 4.9E-16 T 30-10-2018 AD45P2_00500 ed1f3f472e5d7a83f8d0f77a79ba7dd3 81 Pfam PF00085 Thioredoxin 3 77 9.8E-11 T 30-10-2018 IPR013766 Thioredoxin domain GO:0045454 AD45P2_00500 ed1f3f472e5d7a83f8d0f77a79ba7dd3 81 SUPERFAMILY SSF52833 3 79 6.59E-17 T 30-10-2018 IPR036249 Thioredoxin-like superfamily AD45P2_00030 037e7eaff770c3e9a4374e9ce5d0dcff 2201 Pfam PF15711 Interleukin-like EMT inducer 1491 1577 7.1E-9 T 30-10-2018 IPR039477 ILEI/PANDER domain AD45P2_00030 037e7eaff770c3e9a4374e9ce5d0dcff 2201 Gene3D G3DSA:2.10.10.20 742 804 2.8E-5 T 30-10-2018 AD45P2_00240 a61a694de2d9031be763c5aa3f07b98f 153 Pfam PF10686 Protein of unknown function (DUF2493) 13 76 2.0E-10 T 30-10-2018 IPR019627 Mycobacteriophage D29, Gp61 AD45P2_00570 7cd1b580a14521fabc5635a3640daeab 136 SUPERFAMILY SSF103084 37 127 1.7E-7 T 30-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 AD45P2_00430 436dbe9e9ab94c33262ea38ab9b9d755 149 Pfam PF11351 Holin of 3TMs, for gene-transfer release 7 133 1.5E-24 T 30-10-2018 IPR021497 Holin of 3TMs, for gene-transfer release AD45P2_00260 177ea06661a90dc8af4232305be8075f 435 SUPERFAMILY SSF52540 5 278 3.61E-10 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AD45P2_00045 24485a3e984d7b87c8a58a2534a77c36 381 TIGRFAM TIGR04387 capsid_maj_N4: major capsid protein, N4-gp56 family 11 375 1.4E-55 T 30-10-2018 AD45P2_00280 89316000b829836f7dc394f850d841ac 90 Pfam PF11195 Protein of unknown function (DUF2829) 5 89 3.4E-21 T 30-10-2018 IPR021361 Protein of unknown function DUF2829 AD45P2_00525 b9f2d6c228b57a30ced42eb036dad206 153 Pfam PF13479 AAA domain 2 138 2.6E-10 T 30-10-2018 AD45P2_00615 d981b35baf9d546b7112be96b7cba830 109 Gene3D G3DSA:1.10.530.40 1 107 1.7E-8 T 30-10-2018