locus-tag	class	description
D1814_00010	ENOG4105DNH	Major Facilitator
D1814_00045	ENOG4105CGK	Exodeoxyribonuclease III
D1814_00070	ENOG4105D60	lipoprotein releasing system transmembrane protein
D1814_00080	ENOG4108JA2	transcriptioN-repair coupling factor
D1814_00090	ENOG4108WBT	adenosyltransferase
D1814_00095	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D1814_00105	ENOG4108Z66	YbaK ebsC protein
D1814_00115	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D1814_00120	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D1814_00125	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D1814_00135	ENOG4105JEU	Glycosyl transferase, family 2
D1814_00140	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
D1814_00155	ENOG4107T8Q	Glycosyl transferase (Group 1
D1814_00170	ENOG4105C74	pyruvyl transferase
D1814_00180	ENOG4107RA4	Glycosyl transferase (Group 1
D1814_00190	ENOG4107QPH	glycogen) synthase
D1814_00200	ENOG4105BZU	Histidine kinase
D1814_00225	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
D1814_00230	ENOG4108QV3	biosynthesis protein
D1814_00235	ENOG4105DAY	polysaccharide export protein
D1814_00245	ENOG4105D3Q	Sugar transferase
D1814_00265	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D1814_00270	ENOG41082NX	50s ribosomal protein l35
D1814_00275	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D1814_00280	ENOG4105C22	threonyL-tRNA synthetase
D1814_00290	ENOG4105CHR	reductase
D1814_00320	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D1814_00325	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D1814_00330	ENOG4105HF0	Membrane
D1814_00335	ENOG4105C5R	Aminotransferase
D1814_00365	ENOG4105BZU	Histidine kinase
D1814_00370	ENOG4105BZU	Histidine kinase
D1814_00375	ENOG4105BZU	Histidine kinase
D1814_00385	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D1814_00390	ENOG4105C7N	Xanthine uracil vitamin C permease
D1814_00395	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1814_00400	ENOG4105VT3	DNA binding domain protein, excisionase family
D1814_00420	ENOG4108R86	Transcriptional regulator
D1814_00430	ENOG4105C7W	Xanthine dehydrogenase
D1814_00450	ENOG4107QUY	Guanine deaminase
D1814_00460	ENOG4105BZU	Histidine kinase
D1814_00490	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D1814_00510	ENOG4105BZS	acriflavin resistance protein
D1814_00520	ENOG4105BZU	Histidine kinase
D1814_00525	ENOG4105BZU	Histidine kinase
D1814_00545	ENOG4105F1J	Homogentisate 1,2-dioxygenase
D1814_00560	ENOG4105C5Y	PTS System
D1814_00565	ENOG4105KUZ	arsenate reductase
D1814_00570	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D1814_00595	ENOG4105K8R	UPF0145 protein
D1814_00605	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
D1814_00610	ENOG4105BZU	Histidine kinase
D1814_00615	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
D1814_00620	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
D1814_00625	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
D1814_00630	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1814_00640	ENOG4105F8C	transglutaminase domain-containing protein
D1814_00645	ENOG4105TMB	Formate nitrite transporter
D1814_00650	ENOG4107TPY	serine threonine protein kinase
D1814_00655	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
D1814_00660	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D1814_00665	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
D1814_00670	ENOG4105M08	Membrane
D1814_00680	ENOG4105ETT	transcriptional Regulator, LysR family
D1814_00690	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D1814_00695	ENOG4108YY7	Invasion gene expression up-regulator SirB
D1814_00700	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1814_00705	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D1814_00710	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D1814_00715	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D1814_00720	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
D1814_00725	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D1814_00735	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D1814_00750	ENOG4105DQ4	alcohol dehydrogenase
D1814_00755	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D1814_00760	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D1814_00765	ENOG4105C3G	gtp-binding protein
D1814_00770	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1814_00830	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
D1814_00835	ENOG4105KVH	Transcriptional regulator
D1814_00840	ENOG4107XWI	flavin reductase domain protein, FMN-binding
D1814_00845	ENOG4108S4H	thioesterase Superfamily protein
D1814_00850	ENOG4107RNH	Outer membrane receptor FepA
D1814_00880	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D1814_00885	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D1814_00895	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D1814_00900	ENOG4108JU5	Magnesium and cobalt efflux protein
D1814_00905	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D1814_00910	ENOG4105C6K	Malic enzyme
D1814_00915	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D1814_00920	ENOG4108ZNX	Heat shock protein
D1814_00940	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D1814_00945	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D1814_00950	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D1814_00955	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D1814_00965	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D1814_00970	ENOG4105BZU	Histidine kinase
D1814_00975	ENOG41085AF	Cytochrome
D1814_00980	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D1814_00985	ENOG4105CFG	Acts as a chaperone (By similarity)
D1814_00990	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D1814_00995	ENOG4105BZU	Histidine kinase
D1814_01015	ENOG4105CY2	Citrate transporter
D1814_01020	ENOG4105DWV	Homoserine O-trans-acetylase
D1814_01030	ENOG4105DTD	Dehydrogenase
D1814_01035	ENOG4105C0A	alcohol dehydrogenase
D1814_01040	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D1814_01045	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
D1814_01050	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D1814_01055	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D1814_01060	ENOG4105FQ6	thiopurine methyltransferase
D1814_01065	ENOG4106BRA	Membrane
D1814_01075	ENOG4108UW5	maltose o-acetyltransferase
D1814_01080	ENOG4105FE9	pseudouridine synthase
D1814_01085	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
D1814_01095	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D1814_01100	ENOG4105DB7	PHP domain protein
D1814_01105	ENOG4105CRQ	synthase (Component I)
D1814_01115	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D1814_01120	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D1814_01125	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D1814_01130	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D1814_01135	ENOG4105K9H	YciI-like protein
D1814_01150	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D1814_01160	ENOG4105DSF	transport protein
D1814_01165	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
D1814_01170	ENOG4105ECP	epimerase
D1814_01175	ENOG4105CV6	ABC transporter, permease
D1814_01180	ENOG4108I0Y	(ABC) transporter
D1814_01200	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
D1814_01245	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D1814_01275	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D1814_01285	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D1814_01290	ENOG4108JJ7	ABC transporter
D1814_01305	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
D1814_01310	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
D1814_01315	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
D1814_01320	ENOG4105KJF	protein tyrosine phosphatase
D1814_01325	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
D1814_01330	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D1814_01335	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D1814_01340	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1814_01345	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D1814_01350	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D1814_01375	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1814_01390	ENOG4105C5S	asparaginyl-tRNA synthetase
D1814_01395	ENOG4105CF7	AraC family transcriptional regulator
D1814_01400	ENOG4105EMU	Dehydrogenase
D1814_01415	ENOG4105F1S	paraquat-inducible protein a
D1814_01420	ENOG4105DY2	Paraquat-inducible protein b
D1814_01430	ENOG4105BZU	Histidine kinase
D1814_01450	ENOG4108ESX	Receptor
D1814_01455	ENOG4108XG4	DNA-binding transcriptional regulator
D1814_01465	ENOG4105BZS	acriflavin resistance protein
D1814_01470	ENOG4105W87	Cbs domain
D1814_01475	ENOG4108VKG	metal-dependent hydrolase
D1814_01480	ENOG4105CIS	alcohol dehydrogenase
D1814_01485	ENOG4105HEI	LysR family (Transcriptional regulator
D1814_01500	ENOG4105BZU	Histidine kinase
D1814_01515	ENOG4105DS1	cytochrome b561
D1814_01520	ENOG4108W6C	Dehydrogenase
D1814_01540	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
D1814_01545	ENOG4108NRW	Phospholipase, patatin family
D1814_01560	ENOG4105CHR	reductase
D1814_01575	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D1814_01595	ENOG4105UFD	tol-pal system protein YbgF
D1814_01600	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D1814_01605	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
D1814_01615	ENOG4105M8F	Biopolymer transport protein exbD tolR
D1814_01620	ENOG4105E02	MotA TolQ exbB proton channel
D1814_01625	ENOG4107YD3	Thioesterase
D1814_01630	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D1814_01635	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D1814_01640	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D1814_01645	ENOG4108TIT	dATP pyrophosphohydrolase
D1814_01650	ENOG4105C9M	aspartyl-trna synthetase
D1814_01665	ENOG4105I03	Flagellin
D1814_01670	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_01680	ENOG4107WP9	Histidine kinase
D1814_01690	ENOG4105BZU	Histidine kinase
D1814_01700	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1814_01710	ENOG4108ZJT	translation initiation factor, Sui1
D1814_01715	ENOG4108VYJ	response regulator receiver protein
D1814_01730	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D1814_01740	ENOG4105E39	Enoyl-CoA hydratase
D1814_01745	ENOG4105EN6	Membrane
D1814_01750	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D1814_01755	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D1814_01760	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D1814_01765	ENOG4105K5M	30s ribosomal protein S16
D1814_01780	ENOG4105BZ1	(ABC) transporter
D1814_01785	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D1814_01830	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D1814_01835	ENOG4106KVJ	cytochrome C assembly protein
D1814_01840	ENOG4108JU6	CBS domain protein
D1814_01850	ENOG4108BY2	phosphohistidine phosphatase
D1814_01870	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1814_01875	ENOG4105CHU	acetyl-coa acetyltransferase
D1814_01880	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1814_01900	ENOG4107QVM	von Willebrand factor, type A
D1814_01925	ENOG4105BZU	Histidine kinase
D1814_01930	ENOG4105CK7	Sodium proline symporter
D1814_01935	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D1814_01940	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
D1814_01945	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
D1814_01950	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
D1814_01975	ENOG4105CAQ	asparagine synthetase
D1814_01985	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D1814_01990	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
D1814_02000	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D1814_02005	ENOG4107QJQ	Mate efflux family protein
D1814_02020	ENOG4105DGN	Electron transport complex
D1814_02025	ENOG4108R3D	Electron transport complex
D1814_02035	ENOG4105D6A	Electron transport complex
D1814_02040	ENOG4108UQQ	Electron transport complex
D1814_02045	ENOG4105DZB	Electron transport complex
D1814_02050	ENOG4105CSM	endonuclease III
D1814_02070	ENOG4105VEQ	Cold shock protein
D1814_02075	ENOG4108UYE	Lactoylglutathione lyase
D1814_02080	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
D1814_02085	ENOG4105EIY	sodium-type flagellar protein motY
D1814_02090	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
D1814_02095	ENOG4105D3R	alkyl hydroperoxide reductase
D1814_02120	ENOG4105D05	Receptor
D1814_02125	ENOG4105M2J	Glutaredoxin
D1814_02130	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D1814_02135	ENOG4105CYN	Serine protein kinase
D1814_02140	ENOG4106AKX	UPF0229 protein
D1814_02145	ENOG4105ED1	spovr family
D1814_02155	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D1814_02160	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
D1814_02185	ENOG4105D9M	gamma-glutamylcysteine synthetase
D1814_02200	ENOG4108W1A	pseudouridine synthase
D1814_02205	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
D1814_02210	ENOG4105CRK	lysyL-tRNA synthetase
D1814_02230	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1814_02275	ENOG4105WH1	Two component transcriptional regulator luxr family
D1814_02280	ENOG4105DZG	Dehydrogenase
D1814_02290	ENOG4107QX3	carboxylase
D1814_02305	ENOG4105C75	arginyL-tRNA synthetase
D1814_02310	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D1814_02320	ENOG4105BZU	Histidine kinase
D1814_02325	ENOG4105CV8	reductase
D1814_02335	ENOG4105F27	Major Facilitator
D1814_02340	ENOG4105HEI	LysR family (Transcriptional regulator
D1814_02355	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
D1814_02395	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
D1814_02405	ENOG410822N	TonB family
D1814_02410	ENOG4109015	Biopolymer transport protein exbD tolR
D1814_02435	ENOG4107RDJ	Sulfotransferase
D1814_02465	ENOG4107RDJ	Sulfotransferase
D1814_02470	ENOG4108KPZ	tonB-dependent Receptor
D1814_02475	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
D1814_02490	ENOG4107RDP	Dehydrogenase
D1814_02495	ENOG4108XM1	transcriptional regulator AsnC family
D1814_02500	ENOG4108RXX	maleylacetoacetate isomerase
D1814_02515	ENOG4105MIR	Phenylalanine 4-monooxygenase
D1814_02530	ENOG41087YS	Phage shock protein A
D1814_02535	ENOG4105E51	psp operon transcriptional activator
D1814_02540	ENOG4105DEF	Extracellular solute-binding protein, family 5
D1814_02545	ENOG4108I5W	peptide transport system, permease protein
D1814_02550	ENOG4108EU3	peptide transport system, permease
D1814_02555	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
D1814_02560	ENOG4108JQ2	peptide transport system atp-binding protein
D1814_02565	ENOG4105D9Q	decarboxylase (Beta subunit)
D1814_02570	ENOG4107QSA	Oxaloacetate decarboxylase
D1814_02595	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
D1814_02600	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D1814_02605	ENOG4108004	Modulates RecA activity (By similarity)
D1814_02615	ENOG4105C9K	Endothelin-converting enzyme 1
D1814_02620	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
D1814_02630	ENOG4105CHH	sulfate transporter
D1814_02635	ENOG4107B2H	carbonic anhydrase
D1814_02640	ENOG4105C5Q	Transcriptional regulator
D1814_02645	ENOG4105DZ2	Transcriptional regulator
D1814_02650	ENOG4105NBK	UPF0345 protein
D1814_02660	ENOG4105C3R	Methionine synthase
D1814_02665	ENOG4105C3R	Methionine synthase
D1814_02670	ENOG4105CVG	Homoserine O-transsuccinylase
D1814_02680	ENOG4105YFD	chemotaxis, protein
D1814_02690	ENOG4107QJE	Chromosome Partitioning Protein
D1814_02700	ENOG4105CBS	Chea signal transduction histidine kinase
D1814_02705	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
D1814_02710	ENOG4108VYJ	response regulator receiver protein
D1814_02715	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1814_02725	ENOG4105FZW	flagellar biosynthesis regulator FlhF
D1814_02730	ENOG4105D7B	Flagellar biosynthesis protein flha
D1814_02735	ENOG4105D00	flagellar biosynthetic protein flhB
D1814_02740	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
D1814_02745	ENOG4105VS8	Flagellar biosynthetic protein fliq
D1814_02750	ENOG4105CN7	Flagellar biosynthetic protein FliP
D1814_02760	ENOG4105DD5	Flagellar motor switch protein
D1814_02765	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D1814_02785	ENOG4108JIR	Flagellum-specific ATP synthase
D1814_02795	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D1814_02800	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
D1814_02805	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
D1814_02810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_02815	ENOG4105BZU	Histidine kinase
D1814_02820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_02830	ENOG4105C5E	polysaccharide biosynthesis protein
D1814_02835	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1814_02840	ENOG4105D2T	synthase
D1814_02845	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1814_02850	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1814_02870	ENOG4105F0R	Cytidylyltransferase
D1814_02885	ENOG4105MQ3	flagellar protein FliS
D1814_02895	ENOG41063QE	flagellar protein FlaG
D1814_02900	ENOG4105I03	Flagellin
D1814_02905	ENOG4105I03	Flagellin
D1814_02910	ENOG4105I03	Flagellin
D1814_02920	ENOG4105DTJ	flagellar hook-associated protein
D1814_02925	ENOG4105E1Q	flagellar hook-associated protein
D1814_02930	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
D1814_02935	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D1814_02940	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D1814_02945	ENOG4105CGA	flagellar basal-body rod protein FlgG
D1814_02950	ENOG4108KPB	Flagellar basal-body rod protein FlgF
D1814_02955	ENOG4105BZE	flagellar hook protein, FlgE
D1814_02960	ENOG4105W00	Flagellar hook capping protein
D1814_02965	ENOG4108ZC9	flagellar basal-body rod protein flgc
D1814_02970	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
D1814_02975	ENOG4105BZU	Histidine kinase
D1814_02980	ENOG4107R88	Chemotaxis protein (CheV)
D1814_03020	ENOG4108ZXC	Two component transcriptional regulator, luxr family
D1814_03030	ENOG4108JJA	ABC, transporter
D1814_03035	ENOG4105CDV	Ompa motb domain protein
D1814_03050	ENOG4108DG9	Smr protein MutS2
D1814_03055	ENOG4108ETH	Formylglycinamide ribotide synthetase
D1814_03060	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D1814_03065	ENOG4108Z6B	deaminase
D1814_03080	ENOG4105BZU	Histidine kinase
D1814_03085	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D1814_03090	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D1814_03095	ENOG4105C0B	DNA polymerase III (alpha subunit)
D1814_03100	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D1814_03105	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1814_03115	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D1814_03120	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
D1814_03130	ENOG4105DZP	Membrane-associated zinc metalloprotease
D1814_03135	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
D1814_03140	ENOG4105KNE	Phosphatidate cytidylyltransferase
D1814_03145	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D1814_03150	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D1814_03155	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D1814_03160	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D1814_03165	ENOG4105CE9	30S ribosomal protein S2
D1814_03170	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
D1814_03175	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D1814_03180	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D1814_03185	ENOG4105QDK	Flavodoxin
D1814_03190	ENOG4105DR9	pseudouridine synthase
D1814_03225	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
D1814_03235	ENOG4105BZU	Histidine kinase
D1814_03240	ENOG4105EWT	decarboxylase family
D1814_03255	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D1814_03260	ENOG4105KQC	Competence protein
D1814_03265	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
D1814_03280	ENOG4105ESV	Glycosyl transferase, family 4
D1814_03290	ENOG4107V1M	polysaccharide export protein
D1814_03310	ENOG4105DUX	Transporter
D1814_03320	ENOG4105CMR	udp-glucose 4-epimerase
D1814_03325	ENOG410903C	(LipO)protein
D1814_03335	ENOG4108M1T	Cytochrome c-type biogenesis protein
D1814_03340	ENOG4107QX9	Thiol disulfide interChange protein
D1814_03345	ENOG4105DA4	cytochrome c-type biogenesis protein
D1814_03350	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
D1814_03355	ENOG4105X3C	heme exporter protein
D1814_03360	ENOG41060IM	Heme exporter protein
D1814_03365	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
D1814_03370	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
D1814_03385	ENOG4108SDH	ABC, transporter
D1814_03390	ENOG4108IUW	ABC transporter
D1814_03395	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D1814_03405	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D1814_03410	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D1814_03415	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D1814_03430	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D1814_03435	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D1814_03440	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1814_03445	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1814_03465	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D1814_03480	ENOG4105C1J	atp-dependent rna helicase
D1814_03485	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D1814_03490	ENOG4105CSA	Coproporphyrinogen iii oxidase
D1814_03520	ENOG41067MG	lrgb family
D1814_03560	ENOG4105FCW	Major Facilitator superfamily
D1814_03570	ENOG4105D64	Mechanosensitive ion channel
D1814_03590	ENOG4105C5H	ABC transporter
D1814_03600	ENOG4105RW8	MltA-interacting MipA family protein
D1814_03610	ENOG4105C84	Histidine ammonia-lyase
D1814_03615	ENOG4105CGP	Urocanate hydratase
D1814_03625	ENOG4105CI2	imidazolone-5-propionate hydrolase
D1814_03645	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
D1814_03655	ENOG4105EYH	Exonuclease
D1814_03670	ENOG4107SDU	Methyl-accepting chemotaxis
D1814_03680	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
D1814_03695	ENOG4108ZHJ	Organic hydroperoxide resistance protein
D1814_03700	ENOG4105K56	Transcriptional regulator
D1814_03705	ENOG4108UT2	hemolysin iii
D1814_03715	ENOG4105C5Q	Transcriptional regulator
D1814_03725	ENOG4105CJ3	phosphate transporter
D1814_03735	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D1814_03745	ENOG4105C8U	phosphate abc transporter
D1814_03760	ENOG4105C9X	ppx gppa phosphatase
D1814_03765	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D1814_03770	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
D1814_03780	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D1814_03790	ENOG4105WYW	fructose-bisphosphate aldolase
D1814_03795	ENOG4105BZA	Phosphoglycerate kinase
D1814_03800	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1814_03805	ENOG4105CV1	Transketolase (EC 2.2.1.1)
D1814_03810	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D1814_03830	ENOG4105BZU	Histidine kinase
D1814_03835	ENOG4108RNG	Permease of the drug metabolite transporter
D1814_03840	ENOG4105D05	Receptor
D1814_03855	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1814_03865	ENOG4108RCM	Nitroreductase
D1814_03870	ENOG4105BZU	Histidine kinase
D1814_03885	ENOG4105CDY	transcriptional regulatory protein
D1814_03890	ENOG4105D6Z	AFG1 family ATPase
D1814_03900	ENOG4105C0H	protease
D1814_03905	ENOG4105C0H	protease
D1814_03910	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D1814_03915	ENOG4105VFK	BolA family
D1814_03925	ENOG4105E3I	toluene tolerance
D1814_03930	ENOG4107PE3	Mammalian cell entry related domain protein
D1814_03935	ENOG4105CY3	ABC transporter, permease
D1814_03940	ENOG4105DHJ	ABC, transporter
D1814_03950	ENOG4105C2X	Arabinose 5-phosphate isomerase
D1814_03955	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
D1814_03965	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
D1814_03970	ENOG4108IUZ	ABC transporter
D1814_03975	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1814_03980	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
D1814_03985	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
D1814_03990	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
D1814_03995	ENOG41080Z8	PHOSPHOCARRIER protein
D1814_04000	ENOG4105CJW	magnesium transporter
D1814_04005	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1814_04020	ENOG4105KB2	stringent starvation protein b
D1814_04025	ENOG4107MKT	Stringent starvation protein a
D1814_04030	ENOG4105EIX	cytochrome c1
D1814_04035	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D1814_04040	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D1814_04045	ENOG4108UJD	30S ribosomal protein S9
D1814_04050	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D1814_04065	ENOG4105D05	Receptor
D1814_04080	ENOG4105DXN	mazG family
D1814_04085	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D1814_04090	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D1814_04095	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
D1814_04100	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D1814_04105	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
D1814_04115	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D1814_04120	ENOG4105T95	Thiol disulfide interChange protein
D1814_04125	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1814_04130	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
D1814_04135	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D1814_04140	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D1814_04145	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D1814_04150	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D1814_04155	ENOG4105NWN	ApaG protein
D1814_04160	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
D1814_04165	ENOG4108NVR	Methyl-accepting chemotaxis
D1814_04170	ENOG4105CFH	Aspartokinase
D1814_04180	ENOG4107QIJ	Aconitate hydratase 2
D1814_04195	ENOG4108SA1	esterase
D1814_04200	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D1814_04205	ENOG4107QIJ	Aconitate hydratase 2
D1814_04220	ENOG4105CEY	Amp-dependent synthetase and ligase
D1814_04225	ENOG4105BZU	Histidine kinase
D1814_04230	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1814_04240	ENOG41067XB	TonB family
D1814_04245	ENOG4109015	Biopolymer transport protein exbD tolR
D1814_04285	ENOG4105BZU	Histidine kinase
D1814_04290	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1814_04295	ENOG4105BZU	Histidine kinase
D1814_04300	ENOG4105DH7	May be involved in recombination (By similarity)
D1814_04305	ENOG4108JCI	Transcriptional regulator
D1814_04310	ENOG4105DKK	Benzoate
D1814_04325	ENOG4105K59	histidine triad (HIT) protein
D1814_04330	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D1814_04340	ENOG4107ZVW	dihydroneopterin aldolase
D1814_04345	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
D1814_04355	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D1814_04360	ENOG4105VCC	30S ribosomal protein S21
D1814_04370	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D1814_04380	ENOG4105C8Q	Methyl-accepting chemotaxis
D1814_04395	ENOG4105BZS	acriflavin resistance protein
D1814_04410	ENOG4105MP9	class II Aldolase
D1814_04415	ENOG4105CXK	mandelate racemase muconate lactonizing
D1814_04425	ENOG4105CHR	reductase
D1814_04430	ENOG4105CSU	acyl-Coa dehydrogenase
D1814_04445	ENOG4105C58	cytochrome c oxidase accessory protein ccog
D1814_04450	ENOG4105E27	serine threonine protein kinase
D1814_04455	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1814_04460	ENOG4108Z33	Thiol disulfide Interchange Protein
D1814_04475	ENOG4105D7T	ABC transporter
D1814_04490	ENOG4107SDU	Methyl-accepting chemotaxis
D1814_04495	ENOG4107QYG	anthranilate phosphoribosyltransferase
D1814_04500	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1814_04510	ENOG4105WZK	nitrite reductase NADPH small subunit
D1814_04515	ENOG4107QZF	nitrite reductase NADPH large subunit
D1814_04525	ENOG4105CHH	sulfate transporter
D1814_04550	ENOG4105M85	Bola protein
D1814_04560	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D1814_04565	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1814_04570	ENOG41068WN	
D1814_04580	ENOG4105UGU	tonB-dependent Receptor
D1814_04585	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
D1814_04590	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D1814_04595	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D1814_04615	ENOG4107VXZ	Hydrolase
D1814_04625	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1814_04630	ENOG4105IPS	esterase
D1814_04635	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
D1814_04645	ENOG41087AY	ADP-Ribose pyrophosphatase
D1814_04650	ENOG4105DFG	type I secretion outer membrane protein
D1814_04665	ENOG4105C1J	atp-dependent rna helicase
D1814_04670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1814_04680	ENOG4108IAB	Phoh family
D1814_04695	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
D1814_04700	ENOG4105D3G	Pseudouridine synthase
D1814_04715	ENOG4105EYM	Major Facilitator superfamily
D1814_04720	ENOG4105BZU	Histidine kinase
D1814_04725	ENOG4105BZU	Histidine kinase
D1814_04730	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1814_04735	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D1814_04740	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D1814_04745	ENOG4105HF0	Membrane
D1814_04750	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
D1814_04755	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D1814_04780	ENOG4105GR3	Histidine kinase
D1814_04785	ENOG4105ETX	regulatoR
D1814_04790	ENOG4105BZS	acriflavin resistance protein
D1814_04815	ENOG4105C8Q	Methyl-accepting chemotaxis
D1814_04825	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D1814_04830	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
D1814_04835	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
D1814_04840	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
D1814_04845	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D1814_04850	ENOG4108UM1	dedA family
D1814_04855	ENOG4108K5P	(LipO)protein
D1814_04875	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D1814_04880	ENOG4105K46	50S ribosomal protein l27
D1814_04885	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D1814_04895	ENOG4105EAH	synthase
D1814_04905	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
D1814_04910	ENOG4107SC1	transglycosylase
D1814_04915	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1814_04920	ENOG4105CHU	acetyl-coa acetyltransferase
D1814_05040	ENOG4105I4A	GCN5-related N-acetyltransferase
D1814_05045	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
D1814_05055	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D1814_05065	ENOG4105K3M	)-transporter
D1814_05085	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
D1814_05100	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D1814_05105	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D1814_05125	ENOG4107S6Z	Na H antiporter
D1814_05130	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D1814_05165	ENOG4105C26	Dehydrogenase
D1814_05170	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D1814_05190	ENOG4107QR8	Thioredoxin
D1814_05200	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D1814_05225	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D1814_05230	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D1814_05235	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D1814_05240	ENOG4105BZU	Histidine kinase
D1814_05245	ENOG4105CH2	amidohydrolase
D1814_05260	ENOG4105K63	Thioredoxin
D1814_05265	ENOG4105C1J	atp-dependent rna helicase
D1814_05270	ENOG4105C9X	ppx gppa phosphatase
D1814_05275	ENOG4105D52	delta-aminolevulinic acid dehydratase
D1814_05285	ENOG4105F8V	Hydrolase, tatD family
D1814_05295	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D1814_05300	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
D1814_05305	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D1814_05315	ENOG4108ZP8	Acetolactate synthase small subunit
D1814_05320	ENOG4105C7K	acetolactate synthase
D1814_05335	ENOG4107RDJ	Sulfotransferase
D1814_05355	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
D1814_05360	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D1814_05365	ENOG4105DJ4	phosphatidylserine decarboxylase
D1814_05375	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
D1814_05385	ENOG4105PXI	polysaccharide deacetylase
D1814_05395	ENOG41063SB	peptidase
D1814_05400	ENOG4107YZP	Rhodanese domain protein
D1814_05405	ENOG4105VW4	glutaredoxin 3
D1814_05410	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
D1814_05415	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D1814_05425	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D1814_05430	ENOG4108EUD	Lysophospholipase
D1814_05435	ENOG4105E0F	Histidine kinase
D1814_05440	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D1814_05455	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D1814_05465	ENOG4108Z5K	methylglyoxal synthase
D1814_05470	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D1814_05475	ENOG4105CAS	nag kinase
D1814_05485	ENOG4105CDH	Citrulline--aspartate ligase
D1814_05490	ENOG4105CH7	arginosuccinase
D1814_05495	ENOG4107QZM	n-acetylglutamate synthase
D1814_05500	ENOG4105BZU	Histidine kinase
D1814_05535	ENOG4105CH6	catalase
D1814_05555	ENOG4105CYM	Glutathione S-transferase
D1814_05565	ENOG4107R1I	NAD-dependent malic enzyme
D1814_05570	ENOG4108JQC	penicillin-binding protein 1A
D1814_05595	ENOG4105E4G	Type IV pilus
D1814_05600	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D1814_05605	ENOG4105D49	3-dehydroquinate synthase
D1814_05615	ENOG4105DFE	Dna adenine methylase
D1814_05635	ENOG4105DJV	ribulose-phosphate 3-epimerase
D1814_05640	ENOG4105C31	Tryptophanyl-tRNA synthetase
D1814_05655	ENOG4105C8Y	Acetylornithine aminotransferase
D1814_05665	ENOG4105C26	Dehydrogenase
D1814_05675	ENOG4105BZU	Histidine kinase
D1814_05685	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1814_05690	ENOG4105BZU	Histidine kinase
D1814_05705	ENOG410624X	efflux transporter, rnd family, mfp subunit
D1814_05715	ENOG4105CXT	aspartate transcarbamylase
D1814_05720	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D1814_05730	ENOG4105EZR	dyp-type peroxidase family protein
D1814_05735	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D1814_05745	ENOG4108YZA	Nitrogen regulatory protein pii
D1814_05755	ENOG4108R6W	Transcriptional regulator, ARAC family
D1814_05760	ENOG4105CKW	Inner membrane protein yedI
D1814_05770	ENOG4105BZ4	penicillin-binding protein
D1814_05775	ENOG4105CVE	Lytic murein transglycosylase
D1814_05785	ENOG4105CQ7	ATP-dependent helicase
D1814_05815	ENOG4105DGW	oligopeptidase A
D1814_05820	ENOG4105C8Q	Methyl-accepting chemotaxis
D1814_05840	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
D1814_05850	ENOG4105CPK	Glycosyl transferase (Group 1
D1814_05855	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D1814_05860	ENOG41083MP	50s ribosomal protein l29
D1814_05865	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D1814_05870	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D1814_05875	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D1814_05880	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D1814_05885	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D1814_05890	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D1814_05895	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D1814_05900	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D1814_05910	ENOG4107QHF	type ii secretion system protein e
D1814_05920	ENOG4107QM5	aconitate hydratase
D1814_05930	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D1814_05935	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D1814_05975	ENOG4105C0A	alcohol dehydrogenase
D1814_06000	ENOG4105EAA	nucleoside
D1814_06015	ENOG4105ETE	Transcriptional regulator (LacI family
D1814_06030	ENOG4105BZU	Histidine kinase
D1814_06035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D1814_06065	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
D1814_06070	ENOG4105BZU	Histidine kinase
D1814_06075	ENOG4107SDU	Methyl-accepting chemotaxis
D1814_06080	ENOG4107SDU	Methyl-accepting chemotaxis
D1814_06085	ENOG4108V3W	Chemotaxis protein, CheW
D1814_06090	ENOG4105CBS	Chea signal transduction histidine kinase
D1814_06095	ENOG4108VYJ	response regulator receiver protein
D1814_06100	ENOG4105C8Q	Methyl-accepting chemotaxis
D1814_06105	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1814_06110	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
D1814_06115	ENOG4105BZU	Histidine kinase
D1814_06120	ENOG4107SDU	Methyl-accepting chemotaxis
D1814_06125	ENOG4108V3W	Chemotaxis protein, CheW
D1814_06130	ENOG4105CBS	Chea signal transduction histidine kinase
D1814_06135	ENOG4108VYJ	response regulator receiver protein
D1814_06140	ENOG4105C8Q	Methyl-accepting chemotaxis
D1814_06165	ENOG4105DXB	Major Facilitator superfamily
D1814_06200	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
D1814_06205	ENOG4105CEN	a g-specific adenine glycosylase
D1814_06215	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D1814_06220	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D1814_06225	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1814_06230	ENOG4105BZU	Histidine kinase
D1814_06235	ENOG41065U4	response regulator
D1814_06240	ENOG4105CNT	hydrolase family 2
D1814_06250	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
D1814_06255	ENOG4105N42	UPF0307 protein
D1814_06260	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D1814_06275	ENOG4105C03	ribonuclease
D1814_06280	ENOG4108Z03	MAF-like protein
D1814_06285	ENOG4105VQ7	Rod shape-determining protein MreD
D1814_06290	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
D1814_06295	ENOG4105DFF	Rod shape-determining protein mreb
D1814_06340	ENOG4105D7Q	type ii secretion system
D1814_06345	ENOG4107QHF	type ii secretion system protein e
D1814_06395	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
D1814_06400	ENOG4105E98	transcriptional regulator DeoR family
D1814_06405	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D1814_06425	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1814_06445	ENOG4107XMK	single-stranded DNA-binding protein
D1814_06455	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D1814_06460	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D1814_06465	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D1814_06485	ENOG4107VXZ	Hydrolase
D1814_06490	ENOG4107RDB	Major Facilitator
D1814_06495	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D1814_06525	ENOG4105F0N	pyrophosphate phospho-hydrolase
D1814_06530	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D1814_06535	ENOG4105DFU	Cell wall formation (By similarity)
D1814_06540	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
D1814_06550	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D1814_06570	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D1814_06575	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D1814_06585	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1814_06590	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
D1814_06595	ENOG4105D7W	serine acetyltransferase
D1814_06600	ENOG4105C4R	Atp-dependent dna helicase
D1814_06605	ENOG4105BZU	Histidine kinase
D1814_06610	ENOG4105FR1	rard protein
D1814_06615	ENOG4105CJW	magnesium transporter
D1814_06620	ENOG4108VUY	thioesterase Superfamily protein
D1814_06625	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1814_06640	ENOG4105BZU	Histidine kinase
D1814_06645	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
D1814_06650	ENOG4108NST	exported protein
D1814_06660	ENOG4105C8Q	Methyl-accepting chemotaxis
D1814_06680	ENOG4105CYC	Transferase
D1814_06690	ENOG4105BZS	acriflavin resistance protein
D1814_06695	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D1814_06710	ENOG4105KPY	Small multidrug resistance protein
D1814_06720	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
D1814_06725	ENOG4106TD9	Diguanylate cyclase
D1814_06740	ENOG4105CBX	hi0933 family
D1814_06750	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1814_06755	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
D1814_06775	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
D1814_06780	ENOG4105CB5	ATP-dependent DNA helicase recG
D1814_06785	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
D1814_06790	ENOG4105KME	endoribonuclease L-psp
D1814_06795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D1814_06800	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
D1814_06920	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D1814_06930	ENOG4105BZU	Histidine kinase
D1814_06935	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D1814_06945	ENOG4105ECF	c-methyltransferase
D1814_06950	ENOG410601J	HemY protein
D1814_06955	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D1814_06960	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D1814_06965	ENOG4105D06	uba thif-type nad fad binding protein
D1814_06975	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D1814_06980	ENOG4105D41	biosynthesis protein thiH
D1814_06995	ENOG4105CM6	amino acid regulated cytosolic protein
D1814_07005	ENOG4105DQS	Transcriptional regulator
D1814_07010	ENOG4105C1G	acyl-Coa dehydrogenase
D1814_07020	ENOG4107RNH	Outer membrane receptor FepA
D1814_07085	ENOG4105C3J	Cysteine desulfurase
D1814_07105	ENOG4107ZSV	Receptor
D1814_07120	ENOG41075H3	AraC family transcriptional regulator
D1814_07130	ENOG4105C94	Transporter
D1814_07150	ENOG4105QV4	Tryptophan halogenase
D1814_07160	ENOG4108HKT	sucrose-6-phosphate hydrolase
D1814_07165	ENOG4105ETE	Transcriptional regulator (LacI family
D1814_07170	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
D1814_07180	ENOG4105MPD	Cytochrome
D1814_07185	ENOG4105BZU	Histidine kinase
D1814_07190	ENOG4105C4R	Atp-dependent dna helicase
D1814_07195	ENOG4105W0Z	cytoplasmic protein
D1814_07210	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
D1814_07215	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
D1814_07230	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D1814_07235	ENOG4105CPQ	Dehydrogenase
D1814_07240	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1814_07245	ENOG4105BZU	Histidine kinase
D1814_07260	ENOG4105DKP	glycosyl transferase, family 9
D1814_07270	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D1814_07275	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
D1814_07285	ENOG4105W0E	50S ribosomal protein L33
D1814_07290	ENOG4105KDC	50s ribosomal protein l28
D1814_07295	ENOG4105E3R	(LipO)protein
D1814_07315	ENOG4105W5Q	DNA repair protein (RadC
D1814_07320	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
D1814_07325	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
D1814_07340	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D1814_07345	ENOG4105IIU	Aminopeptidase
D1814_07375	ENOG4105C0B	DNA polymerase III (alpha subunit)
D1814_07420	ENOG4108Z0R	Transferase
D1814_07425	ENOG4105E2X	shikimate dehydrogenase
D1814_07435	ENOG4105EIF	outer membrane protein W
D1814_07440	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
D1814_07445	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D1814_07455	ENOG4108RPN	Protein smg homolog
D1814_07460	ENOG4105C79	DNA protecting protein DprA
D1814_07465	ENOG4108WZM	domain protein
D1814_07470	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D1814_07485	ENOG4105C1A	potassium transporter peripheral membrane
D1814_07490	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D1814_07495	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
D1814_07500	ENOG4105C2M	dna polymerase I
D1814_07505	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D1814_07510	ENOG4106RE7	Cytochrome
D1814_07520	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
D1814_07530	ENOG4108R3E	Dna-3-methyladenine glycosylase i
D1814_07535	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
D1814_07540	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
D1814_07550	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1814_07555	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D1814_07560	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D1814_07565	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D1814_07570	ENOG4105VG0	50S ribosomal protein l34
D1814_07575	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D1814_07580	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D1814_07585	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D1814_07590	ENOG4108VPT	UPF0234 protein
D1814_07595	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D1814_07600	ENOG4105QTB	Flavodoxin
D1814_07615	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D1814_07620	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D1814_07625	ENOG4107QJE	Chromosome Partitioning Protein
D1814_07630	ENOG4105FA0	parb-like partition protein
D1814_07640	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D1814_07650	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D1814_07655	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D1814_07660	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D1814_07665	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D1814_07670	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D1814_07675	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D1814_07690	ENOG4108K3A	Glutathione S-transferase
D1814_07705	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1814_07710	ENOG4105CDV	Ompa motb domain protein
D1814_07720	ENOG41060NJ	transcriptional regulator
D1814_07725	ENOG4105CT4	transporter
D1814_07745	ENOG4105QV4	Tryptophan halogenase
D1814_07755	ENOG4105DSJ	YicC domain protein
D1814_07760	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
D1814_07765	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D1814_07770	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
D1814_07795	ENOG4105CI2	imidazolone-5-propionate hydrolase
D1814_07840	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D1814_07850	ENOG4105C5I	Dehydrogenase
D1814_07875	ENOG4105MA0	exported protein
D1814_07880	ENOG4105CFU	surface antigen
D1814_07890	ENOG4105C2C	drug resistance transporter, Bcr CflA
D1814_07895	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D1814_07900	ENOG4105EMY	transcriptional regulator
D1814_07905	ENOG4105C0P	Mg chelatase subunit ChlI
D1814_07910	ENOG4105EN6	Membrane
D1814_07915	ENOG4105C01	Dihydroxy-acid dehydratase
D1814_07920	ENOG4105C7B	Threonine dehydratase
D1814_07925	ENOG4105E55	glycerol-3-phosphate acyltransferase
D1814_07935	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D1814_07945	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D1814_07975	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
D1814_07980	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D1814_07985	ENOG4108ZX6	Electron transport protein SCO1 SenC
D1814_07995	ENOG4107BJW	polysaccharide deacetylase
D1814_08000	ENOG4107R73	Mate efflux family protein
D1814_08025	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
D1814_08035	ENOG4105MJ2	Competence protein
D1814_08040	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D1814_08060	ENOG4105BZM	domain protein
D1814_08065	ENOG4108RRZ	Transcription elongation factor GreB
D1814_08075	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1814_08085	ENOG41069P5	Protein slyX homolog
D1814_08100	ENOG4105C5H	ABC transporter
D1814_08110	ENOG4105DNZ	Alpha Beta Hydrolase
D1814_08115	ENOG4105YP7	UPF0270 protein
D1814_08130	ENOG4105DJ9	glucan biosynthesis protein
D1814_08135	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
D1814_08150	ENOG4107RK2	ADP-ribose diphosphatase NudE
D1814_08155	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
D1814_08165	ENOG4105C26	Dehydrogenase
D1814_08170	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
D1814_08195	ENOG4105R04	type II secretion system protein K
D1814_08210	ENOG4105VWV	general secretion pathway protein h
D1814_08215	ENOG4108VAU	general secretion pathway protein G
D1814_08220	ENOG4105D7Q	type ii secretion system
D1814_08225	ENOG4107QHF	type ii secretion system protein e
D1814_08235	ENOG4108XKW	General secretion pathway protein C
D1814_08240	ENOG4105VEJ	Heat shock protein
D1814_08245	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
D1814_08250	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
D1814_08255	ENOG4105CJQ	hydrolase, family 31
D1814_08265	ENOG4105E0F	Histidine kinase
D1814_08270	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D1814_08280	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
D1814_08285	ENOG4105EYW	Ion transport protein
D1814_08305	ENOG4105C12	Phosphoribosylglycinamide synthetase
D1814_08315	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D1814_08320	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D1814_08325	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D1814_08330	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D1814_08340	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D1814_08365	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D1814_08385	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D1814_08390	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D1814_08395	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D1814_08400	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D1814_08405	ENOG4105VF7	tolerance protein
D1814_08415	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D1814_08420	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D1814_08430	ENOG4105E2S	oxidase) subunit II
D1814_08435	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D1814_08440	ENOG4105CCU	oxidase (Subunit III)
D1814_08445	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
D1814_08450	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D1814_08455	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
D1814_08470	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D1814_08475	ENOG4105W8H	transhydrogenase (subunit alpha
D1814_08480	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D1814_08490	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D1814_08495	ENOG41066YJ	Beta-lactamase
D1814_08500	ENOG4105D03	DNA-3-methyladenine glycosylase II
D1814_08505	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D1814_08520	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D1814_08525	ENOG4105D9R	oxidoreductase
D1814_08535	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D1814_08580	ENOG4105W1Y	Transcriptional regulator
D1814_08595	ENOG4105PGM	cation diffusion facilitator family transporter
D1814_08625	ENOG4108M4U	conserved membrane protein
D1814_08645	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
D1814_08715	ENOG4105DEN	Luciferase family
D1814_08725	ENOG4105BZU	Histidine kinase
D1814_08735	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
D1814_08740	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D1814_08745	ENOG4105CR8	Transcriptional regulator
D1814_08755	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1814_08760	ENOG4105CEP	NADH dehydrogenase
D1814_08780	ENOG4107TTQ	Alpha beta hydrolase fold
D1814_08785	ENOG4108YZN	class I peptide chain release factor
D1814_08805	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1814_08810	ENOG4105EMN	RNA polymerase sigma factor
D1814_08825	ENOG4105VDW	Csbd family
D1814_08830	ENOG4105Q26	Siderophore-interacting protein
D1814_08860	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
D1814_08875	ENOG4107ENK	receptor
D1814_08885	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
D1814_08900	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_08910	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D1814_08915	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D1814_08925	ENOG4108JJ9	ABC, transporter
D1814_08930	ENOG4108JJ8	(ABC) transporter
D1814_08935	ENOG4107QNK	)-transporter
D1814_08940	ENOG41060NJ	transcriptional regulator
D1814_08960	ENOG4107Y60	(LipO)protein
D1814_08970	ENOG4106B0W	Curli production assembly transport component CsgG
D1814_08985	ENOG4105PGM	cation diffusion facilitator family transporter
D1814_08990	ENOG4107ZSV	Receptor
D1814_08995	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1814_09010	ENOG4105FDP	GntR family transcriptional regulator
D1814_09020	ENOG4106IBS	oxygenase
D1814_09025	ENOG4105HMI	Membrane
D1814_09040	ENOG4105C8Q	Methyl-accepting chemotaxis
D1814_09045	ENOG4105BZU	Histidine kinase
D1814_09050	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
D1814_09070	ENOG4105BZU	Histidine kinase
D1814_09075	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
D1814_09080	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D1814_09085	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D1814_09100	ENOG410804D	Sensor Signal Transduction Histidine Kinase
D1814_09115	ENOG4108RPX	mosc domain containing protein
D1814_09140	ENOG4105CDU	Replicative dna helicase
D1814_09145	ENOG4105CDV	Ompa motb domain protein
D1814_09150	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
D1814_09160	ENOG4105MYN	Zinc uptake regulation protein
D1814_09165	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
D1814_09170	ENOG4105E09	nadh pyrophosphatase
D1814_09175	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D1814_09185	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D1814_09190	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D1814_09195	ENOG4105K8N	protein family UPF0079, ATPase
D1814_09200	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D1814_09210	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D1814_09215	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
D1814_09220	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D1814_09225	ENOG4107QJR	hflk protein
D1814_09230	ENOG4105EPW	hflc protein
D1814_09235	ENOG4105CFC	Transporter
D1814_09240	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D1814_09265	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D1814_09270	ENOG4107IFA	Lipase (EC 3.1.1.3)
D1814_09285	ENOG4105CYM	Glutathione S-transferase
D1814_09290	ENOG4105C3R	Methionine synthase
D1814_09295	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
D1814_09300	ENOG4105D7K	pfkb domain protein
D1814_09305	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D1814_09310	ENOG4107T0X	DNA ligase
D1814_09325	ENOG4107QRT	dEAD DEAH box helicase
D1814_09340	ENOG4105DWY	Agmatine deiminase
D1814_09355	ENOG410642E	Short chain dehydrogenase
D1814_09360	ENOG4105EUJ	GTP cyclohydrolase i
D1814_09370	ENOG4107QW3	Sucrose phosphorylase
D1814_09375	ENOG4105DP8	Major facilitator superfamily MFS_1
D1814_09385	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
D1814_09390	ENOG4107RGM	aldo keto reductase
D1814_09395	ENOG4105QNF	Outer membrane lipoprotein
D1814_09400	ENOG4105EKE	dihydroorotase
D1814_09405	ENOG4105C1J	atp-dependent rna helicase
D1814_09415	ENOG4105C9K	Endothelin-converting enzyme 1
D1814_09420	ENOG4105JSC	dimethylmenaquinone methyltransferase
D1814_09430	ENOG4105BZ1	(ABC) transporter
D1814_09440	ENOG4105PM1	preprotein translocase subunit SecE
D1814_09445	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
D1814_09450	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D1814_09455	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D1814_09460	ENOG4108VZM	50s ribosomal protein L10
D1814_09465	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D1814_09470	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1814_09475	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1814_09480	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D1814_09485	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D1814_09490	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D1814_09495	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D1814_09520	ENOG4105D22	carbon starvation protein
D1814_09550	ENOG4107E2E	PKHD-type hydroxylase
D1814_09555	ENOG4108ESX	Receptor
D1814_09560	ENOG4105EB3	Histidine kinase
D1814_09565	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D1814_09575	ENOG4105DA5	(ABC) transporter
D1814_09580	ENOG4105E3A	(ABC) transporter
D1814_09595	ENOG4105DY8	decarboxylase
D1814_09600	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D1814_09605	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D1814_09610	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D1814_09615	ENOG4105DJ0	Poly(A) Polymerase
D1814_09620	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
D1814_09625	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D1814_09630	ENOG4105PW4	Sugar fermentation stimulation protein homolog
D1814_09635	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D1814_09645	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
D1814_09655	ENOG4106H78	methyltransferase
D1814_09660	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D1814_09665	ENOG4105CAK	Cell division ATP-binding protein ftsE
D1814_09670	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
D1814_09675	ENOG4105D58	Diguanylate phosphodiesterase
D1814_09680	ENOG4105D58	Diguanylate phosphodiesterase
D1814_09685	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1814_09690	ENOG4105SUU	thioesterase domain
D1814_09695	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D1814_09720	ENOG4105SYT	Methylenetetrahydrofolate reductase
D1814_09725	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
D1814_09730	ENOG4105C6K	Malic enzyme
D1814_09740	ENOG4105VFB	Binds the 23S rRNA (By similarity)
D1814_09745	ENOG4105C25	Primosomal protein n'
D1814_09750	ENOG41063M6	Cell Division Protein
D1814_09760	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
D1814_09765	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
D1814_09770	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
D1814_09785	ENOG4105WH1	Two component transcriptional regulator luxr family
D1814_09790	ENOG4108JJA	ABC, transporter
D1814_09795	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
D1814_09805	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D1814_09815	ENOG4105DC8	reductase
D1814_09820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_09825	ENOG4105BZU	Histidine kinase
D1814_09835	ENOG4107Z9R	response regulator
D1814_09840	ENOG4105DGW	oligopeptidase A
D1814_09850	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D1814_09860	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D1814_09865	ENOG4105VEQ	Cold shock protein
D1814_09875	ENOG4108UYU	AsnC family transcriptional regulator
D1814_09880	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D1814_09885	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D1814_09920	ENOG4107VAM	peptidase, m28
D1814_09935	ENOG4107QK7	reductase
D1814_09940	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
D1814_09950	ENOG4108UV7	flagellar protein motX
D1814_09980	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D1814_09985	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D1814_09990	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1814_10000	ENOG4105BZU	Histidine kinase
D1814_10005	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D1814_10010	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D1814_10015	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D1814_10020	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D1814_10025	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D1814_10030	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D1814_10035	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D1814_10040	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D1814_10045	ENOG4105VPB	50S ribosomal protein L30
D1814_10050	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D1814_10055	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D1814_10060	ENOG41067V7	50S ribosomal protein L36
D1814_10065	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D1814_10070	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D1814_10075	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D1814_10080	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1814_10085	ENOG4108ZT0	50S ribosomal protein l17
D1814_10160	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
D1814_10165	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D1814_10170	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
D1814_10175	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D1814_10215	ENOG41063Z6	transcriptional regulator, lysR family
D1814_10220	ENOG4108JJA	ABC, transporter
D1814_10265	ENOG4105D4A	Cell wall formation (By similarity)
D1814_10270	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
D1814_10275	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
D1814_10300	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D1814_10310	ENOG4105CH6	catalase
D1814_10340	ENOG4105D9P	serine threonine protein kinase
D1814_10365	ENOG4105CPC	Aldo Keto reductase
D1814_10380	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D1814_10395	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1814_10405	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1814_10415	ENOG4105BZU	Histidine kinase
D1814_10425	ENOG4107QN1	sodium solute
D1814_10440	ENOG4105BZU	Histidine kinase
D1814_10465	ENOG4105D9N	nucleoside
D1814_10470	ENOG4105DBI	uridine monophosphokinase
D1814_10500	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
D1814_10505	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
D1814_10520	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D1814_10525	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1814_10530	ENOG4105RKW	reductase (By
D1814_10540	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1814_10545	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1814_10550	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1814_10555	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1814_10560	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
D1814_10565	ENOG4105CJ2	(LipO)protein
D1814_10580	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D1814_10590	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D1814_10595	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D1814_10600	ENOG4108R86	Transcriptional regulator
D1814_10605	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
D1814_10610	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
D1814_10620	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
D1814_10625	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
D1814_10630	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
D1814_10635	ENOG4105C26	Dehydrogenase
D1814_10645	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
D1814_10665	ENOG4108Z12	YiaAB two helix domain-containing protein
D1814_10675	ENOG4105E7A	Glutamine amidotransferase
D1814_10680	ENOG4108WAV	Transcriptional regulator
D1814_10690	ENOG4105C5X	domain protein
D1814_10700	ENOG4105EFZ	amidohydrolase
D1814_10710	ENOG4105BZU	Histidine kinase
D1814_10715	ENOG4105KWG	Pfam:DUF1696
D1814_10725	ENOG4105K4T	epimerase
D1814_10730	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D1814_10745	ENOG4107QZ7	Cellulose synthase catalytic subunit
D1814_10755	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
D1814_10760	ENOG4105EJG	cellulose synthase
D1814_10775	ENOG4109015	Biopolymer transport protein exbD tolR
D1814_10785	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
D1814_10800	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1814_10815	ENOG4105C8J	)-transporter
D1814_10820	ENOG4108535	NAD dependent epimerase/dehydratase family
D1814_10835	ENOG4105CUY	Mechanosensitive ion channel
D1814_10840	ENOG4106HNH	Acyl-transferase
D1814_10845	ENOG4106HNH	Acyl-transferase
D1814_10850	ENOG4105C4W	S-formylglutathione hydrolase
D1814_10855	ENOG4105BZU	Histidine kinase
D1814_10890	ENOG4105CPK	Glycosyl transferase (Group 1
D1814_10900	ENOG4108KTU	conserved protein with FAD NAD(P)-binding domain
D1814_10920	ENOG41087YS	Phage shock protein A
D1814_10925	ENOG4105FM1	phage shock protein C
D1814_10945	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
D1814_10950	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
D1814_10955	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
D1814_10965	ENOG4105BZU	Histidine kinase
D1814_10970	ENOG4108RG0	uracil-dna glycosylase
D1814_10980	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
D1814_10990	ENOG4105EJ2	Transcriptional regulator
D1814_11000	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
D1814_11040	ENOG4105CEY	Amp-dependent synthetase and ligase
D1814_11050	ENOG4105CQ2	DNA polymerase
D1814_11060	ENOG4105BZU	Histidine kinase
D1814_11075	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D1814_11080	ENOG4105HF0	Membrane
D1814_11110	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D1814_11135	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D1814_11140	ENOG4108UHU	Aldolase
D1814_11155	ENOG4105BZU	Histidine kinase
D1814_11160	ENOG4105C1J	atp-dependent rna helicase
D1814_11180	ENOG4105BZU	Histidine kinase
D1814_11185	ENOG4105WH1	Two component transcriptional regulator luxr family
D1814_11215	ENOG4105P8Q	Curli production assembly transport component CsgG
D1814_11220	ENOG41086KC	Transcriptional regulator
D1814_11225	ENOG4105CXG	d-lactate dehydrogenase
D1814_11230	ENOG4105C94	Transporter
D1814_11235	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D1814_11240	ENOG4105C26	Dehydrogenase
D1814_11245	ENOG4105JQN	Transcriptional regulator
D1814_11250	ENOG4107SDU	Methyl-accepting chemotaxis
D1814_11255	ENOG4105BZU	Histidine kinase
D1814_11260	ENOG4105WH1	Two component transcriptional regulator luxr family
D1814_11280	ENOG4105BZU	Histidine kinase
D1814_11310	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
D1814_11325	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
D1814_11335	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D1814_11385	ENOG4105CXK	mandelate racemase muconate lactonizing
D1814_11390	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
D1814_11405	ENOG41088PD	hydrolase
D1814_11425	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
D1814_11430	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1814_11435	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
D1814_11440	ENOG4105BZU	Histidine kinase
D1814_11455	ENOG41082AG	Plasmid maintenance system antidote protein
D1814_11470	ENOG4105VC4	domain protein
D1814_11495	ENOG4105EY3	heparinase II III family protein
D1814_11500	ENOG4108N2Y	auxin Efflux
D1814_11505	ENOG4105BZU	Histidine kinase
D1814_11540	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D1814_11555	ENOG4105DC7	peptidase M24
D1814_11570	ENOG4107RF2	cellulose-binding family II protein
D1814_11585	ENOG4105CHR	reductase
D1814_11595	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
D1814_11600	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
D1814_11625	ENOG4105EMK	carboxylate amino acid amine transporter
D1814_11630	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D1814_11640	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1814_11650	ENOG4107R4I	Periplasmic binding protein
D1814_11655	ENOG4105EHG	Permease protein
D1814_11660	ENOG4105E0A	ABC, transporter
D1814_11675	ENOG4108KPZ	tonB-dependent Receptor
D1814_11700	ENOG4105CK5	oxidoreductase
D1814_11720	ENOG4107AUC	
D1814_11745	ENOG4107RNH	Outer membrane receptor FepA
D1814_11785	ENOG4105K6V	RNA polymerase
D1814_11800	ENOG4108K5H	permease YjgP YjgQ family protein
D1814_11805	ENOG4108M8S	permease YjgP YjgQ family protein
D1814_11810	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D1814_11815	ENOG4105MYG	DNA polymerase iii, chi subunit
D1814_11820	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D1814_11825	ENOG4105BZU	Histidine kinase
D1814_11840	ENOG4106TD9	Diguanylate cyclase
D1814_11850	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
D1814_11855	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
D1814_11860	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1814_11865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_11870	ENOG4105CUX	Signal transduction histidine kinase
D1814_11880	ENOG4105C5F	glutamine synthetase
D1814_11885	ENOG4105CI3	gtp-binding protein typa
D1814_11895	ENOG4105CHM	Aminotransferase
D1814_11900	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
D1814_11935	ENOG41090JD	Blue (Type 1) copper domain protein
D1814_11945	ENOG4105C9Q	fumarate hydratase class II
D1814_11950	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
D1814_11955	ENOG4107QMS	site-determining protein
D1814_11960	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
D1814_11965	ENOG4105CSR	polyphosphate kinase 2
D1814_11975	ENOG41069D7	Methyl-accepting chemotaxis
D1814_11980	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D1814_11985	ENOG4108U78	Glutathione S-transferase
D1814_11990	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
D1814_12005	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1814_12015	ENOG4105EDR	glucose galactose transporter
D1814_12020	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
D1814_12025	ENOG4108K5P	(LipO)protein
D1814_12030	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D1814_12050	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
D1814_12055	ENOG4105CJP	fad dependent oxidoreductase
D1814_12070	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D1814_12075	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
D1814_12080	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
D1814_12085	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D1814_12100	ENOG4105BZ8	glutamate synthase
D1814_12105	ENOG4105CBC	glutamate synthase
D1814_12110	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
D1814_12115	ENOG4105BZU	Histidine kinase
D1814_12135	ENOG4105BZU	Histidine kinase
D1814_12145	ENOG4108I0Z	Aconitate hydratase
D1814_12150	ENOG4105BZN	citrate synthase
D1814_12155	ENOG4105CR4	methylisocitrate lyase
D1814_12185	ENOG4105BZU	Histidine kinase
D1814_12205	ENOG4105W4M	Transport-associated protein
D1814_12210	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D1814_12220	ENOG41082RQ	UPF0102 protein
D1814_12225	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
D1814_12230	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D1814_12250	ENOG4105E3Q	saccharopine dehydrogenase
D1814_12260	ENOG4105Z68	AraC Family Transcriptional Regulator
D1814_12295	ENOG4105BZU	Histidine kinase
D1814_12305	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
D1814_12315	ENOG4105D6J	arsenicaL-resistance protein
D1814_12320	ENOG4105CAU	Arsenical resistance protein, ArsH
D1814_12330	ENOG41082YX	Transcriptional regulator, arsr family
D1814_12345	ENOG4105BZU	Histidine kinase
D1814_12350	ENOG4105WH1	Two component transcriptional regulator luxr family
D1814_12360	ENOG4105CC0	LysR family Transcriptional regulator
D1814_12375	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D1814_12380	ENOG4105D98	threonine synthase
D1814_12385	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D1814_12395	ENOG4107QP8	phosphohexose isomerase
D1814_12400	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D1814_12410	ENOG4105D1Q	UPF0246 protein
D1814_12420	ENOG4105VFU	Rna-binding protein
D1814_12425	ENOG4105F27	Major Facilitator
D1814_12435	ENOG4108UMN	azlc family
D1814_12445	ENOG4108QG2	Membrane
D1814_12450	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1814_12455	ENOG4108Z9K	Osmotically inducible protein
D1814_12460	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D1814_12465	ENOG4108SHQ	Glutathione S-transferase
D1814_12480	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1814_12490	ENOG4108VIA	integral membrane protein
D1814_12495	ENOG4105II7	pyrroline-5-carboxylate reductase
D1814_12500	ENOG4105DFA	alanine racemase domain protein
D1814_12505	ENOG4105CZX	twitching motility protein
D1814_12510	ENOG4105CZX	twitching motility protein
D1814_12520	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D1814_12525	ENOG4108UJU	UPF0301 protein
D1814_12530	ENOG4105D7Z	glutathione synthase
D1814_12535	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
D1814_12565	ENOG4105DPW	Major facilitator superfamily MFS_1
D1814_12570	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D1814_12580	ENOG4105BZU	Histidine kinase
D1814_12585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_12595	ENOG4105BZU	Histidine kinase
D1814_12610	ENOG4105EHV	domain protein
D1814_12630	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
D1814_12635	ENOG4108IJF	Heavy metal efflux pump, CzcA
D1814_12655	ENOG4108V6E	Cell division protein mraZ
D1814_12660	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D1814_12665	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D1814_12670	ENOG4105CJN	penicillin-binding protein
D1814_12675	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D1814_12680	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
D1814_12685	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D1814_12690	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D1814_12695	ENOG4105CNI	cell division protein FtsW
D1814_12700	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D1814_12710	ENOG4105CPF	Cell wall formation (By similarity)
D1814_12715	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
D1814_12720	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D1814_12725	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D1814_12730	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1814_12735	ENOG4105DR5	peptidase
D1814_12740	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D1814_12745	ENOG4105M6F	mutator MutT protein
D1814_12750	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
D1814_12755	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
D1814_12760	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
D1814_12765	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D1814_12770	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
D1814_12775	ENOG4105D7Q	type ii secretion system
D1814_12785	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D1814_12790	ENOG4108WIW	Aspartyl protease
D1814_12795	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
D1814_12805	ENOG41073TP	transcriptional regulator
D1814_12810	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
D1814_12815	ENOG4107QSN	dihydrolipoamide acetyltransferase
D1814_12820	ENOG4107QN2	dihydrolipoyl dehydrogenase
D1814_12835	ENOG41064T2	transcriptional regulator, lysR family
D1814_12855	ENOG4105XZD	Fe-S protein
D1814_12880	ENOG4108JQ1	Dehydrogenase
D1814_12885	ENOG4105E66	phosphoriboisomerase A
D1814_12890	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D1814_12895	ENOG4105BZU	Histidine kinase
D1814_12905	ENOG4108RVA	ribokinase
D1814_12920	ENOG4107RAQ	aminopeptidase
D1814_12925	ENOG4105D0A	hydroxylase
D1814_12930	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D1814_12945	ENOG4107RF4	Phosphodiesterase
D1814_12960	ENOG4105RD7	BadF BadG BcrA BcrD
D1814_12965	ENOG4105CE4	GlcNAc 6-P deacetylase
D1814_12970	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D1814_12975	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D1814_12980	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D1814_13005	ENOG4108HRK	Histidine kinase
D1814_13010	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1814_13030	ENOG4105D8V	Glucose sorbosone dehydrogenase
D1814_13035	ENOG4105BZU	Histidine kinase
D1814_13045	ENOG4105BZU	Histidine kinase
D1814_13065	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1814_13090	ENOG4105S8Q	sugar efflux transporter
D1814_13120	ENOG4108VWS	Yaeq family
D1814_13130	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D1814_13155	ENOG4107U9T	Pfam:Ribonuclease_BN
D1814_13160	ENOG4107R7Y	intracellular protease Pfpi family
D1814_13165	ENOG4105EMU	Dehydrogenase
D1814_13170	ENOG4105CHR	reductase
D1814_13175	ENOG4105BZU	Histidine kinase
D1814_13250	ENOG4105C7W	Xanthine dehydrogenase
D1814_13255	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
D1814_13260	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
D1814_13270	ENOG4107XDR	Lactoylglutathione lyase
D1814_13285	ENOG410822N	TonB family
D1814_13290	ENOG4105NA0	Transcriptional regulator
D1814_13300	ENOG4105E0F	Histidine kinase
D1814_13305	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D1814_13335	ENOG4105D6Z	AFG1 family ATPase
D1814_13340	ENOG4105CSU	acyl-Coa dehydrogenase
D1814_13370	ENOG4108Z4X	TRANSCRIPTIONal
D1814_13375	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
D1814_13390	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
D1814_13395	ENOG4105C26	Dehydrogenase
D1814_13425	ENOG4108RWN	rrna methyltransferase
D1814_13430	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
D1814_13455	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D1814_13475	ENOG4105BZU	Histidine kinase
D1814_13490	ENOG4107QPN	acyl-Coa dehydrogenase
D1814_13520	ENOG4105D1S	lipid A biosynthesis
D1814_13530	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
D1814_13540	ENOG41082IR	Excinuclease ABC C subunit domain protein
D1814_13545	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D1814_13560	ENOG4108QV3	biosynthesis protein
D1814_13575	ENOG4105D3Q	Sugar transferase
D1814_13625	ENOG4105PSV	Polysaccharide Biosynthesis Protein
D1814_13630	ENOG4107RA4	Glycosyl transferase (Group 1
D1814_13635	ENOG4107T8Q	Glycosyl transferase (Group 1
D1814_13650	ENOG4107R8N	Glycosyl transferase, family 2
D1814_13655	ENOG4105D7W	serine acetyltransferase
D1814_13680	ENOG4105C0H	protease
D1814_13695	ENOG4107QP3	malate synthase g
D1814_13705	ENOG4107RET	Isocitrate lyase
D1814_13715	ENOG4105G6Z	alkaline phosphatase
D1814_13720	ENOG4105CSV	Glutaminase
D1814_13735	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1814_13750	ENOG4106032	Glutathionylspermidine synthase
D1814_13775	ENOG4108P9J	Phage shock protein A
D1814_13790	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D1814_13795	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D1814_13800	ENOG4105VIE	preprotein translocase, subunit YajC
D1814_13805	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1814_13810	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1814_13820	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
D1814_13825	ENOG4105D7W	serine acetyltransferase
D1814_13830	ENOG4108VAC	response regulator
D1814_13835	ENOG4108HRK	Histidine kinase
D1814_13840	ENOG4105DA5	(ABC) transporter
D1814_13850	ENOG4105CT3	Monooxygenase
D1814_13855	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
D1814_13865	ENOG4105C3J	Cysteine desulfurase
D1814_13875	ENOG4105C3K	feS assembly ATPase SufC
D1814_13880	ENOG4105JRK	feS assembly protein SufD
D1814_13885	ENOG4105C9B	Cysteine desulfurase
D1814_13890	ENOG4108Z4V	iron-sulfur cluster assembly
D1814_13900	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D1814_13905	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D1814_13910	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D1814_13915	ENOG41090FY	type IV pilus biogenesis stability protein PilW
D1814_13920	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
D1814_13925	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D1814_13930	ENOG4105CUT	histidyl-tRNA synthetase
D1814_13935	ENOG4105N21	Membrane
D1814_13940	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D1814_13945	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D1814_13960	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D1814_13965	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1814_13970	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D1814_13985	ENOG4108NVR	Methyl-accepting chemotaxis
D1814_13990	ENOG4105DGU	Histone deacetylase
D1814_13995	ENOG4105HDD	phospholipase
D1814_14005	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D1814_14010	ENOG4108R96	Methyltransferase, YaeB family
D1814_14020	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D1814_14065	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D1814_14070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D1814_14075	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D1814_14080	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D1814_14085	ENOG4105K70	DNA-binding protein
D1814_14090	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D1814_14120	ENOG4105C09	Bile acid
D1814_14125	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
D1814_14140	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
D1814_14145	ENOG4105CJR	Integral membrane protein (MviN
D1814_14150	ENOG4105DTN	riboflavin biosynthesis protein ribF
D1814_14155	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D1814_14160	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D1814_14165	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
D1814_14170	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
D1814_14230	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
D1814_14235	ENOG4108YZA	Nitrogen regulatory protein pii
D1814_14240	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D1814_14245	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
D1814_14250	ENOG4105Y75	tpr repeat protein
D1814_14265	ENOG4108IYU	L-aspartate oxidase
D1814_14270	ENOG4105EMN	RNA polymerase sigma factor
D1814_14290	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D1814_14295	ENOG4105C3F	Signal peptidase i
D1814_14300	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D1814_14305	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D1814_14310	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D1814_14315	ENOG4105EYA	deoxyribonuclease
D1814_14325	ENOG4105EAC	phosphoserine phosphatase
D1814_14335	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D1814_14345	ENOG4105C5H	ABC transporter
D1814_14350	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1814_14355	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D1814_14360	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
D1814_14365	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D1814_14380	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D1814_14385	ENOG4107YIM	Involved in the transcription termination process (By similarity)
D1814_14390	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D1814_14395	ENOG4108ZAI	phosphatidylglycerophosphatase a
D1814_14400	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D1814_14405	ENOG4105CTB	Polyprenyl synthetase
D1814_14410	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D1814_14415	ENOG4105E14	MotA TolQ exbB proton channel
D1814_14420	ENOG4106VK6	Flagellar motor protein
D1814_14425	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D1814_14440	ENOG4105EMU	Dehydrogenase
D1814_14455	ENOG4105K6V	RNA polymerase
D1814_14465	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1814_14470	ENOG4105C34	Pseudouridine synthase
D1814_14475	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D1814_14480	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1814_14485	ENOG4105CXG	d-lactate dehydrogenase
D1814_14505	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
D1814_14545	ENOG4105E18	UPF0276 protein
D1814_14555	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
D1814_14560	ENOG4107QMP	dna polymerase iii subunits gamma and tau
D1814_14565	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D1814_14570	ENOG4105BZU	Histidine kinase
D1814_14575	ENOG4105BZU	Histidine kinase
D1814_14585	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D1814_14590	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D1814_14595	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D1814_14620	ENOG4105C3F	Signal peptidase i
D1814_14625	ENOG4105S64	Formate nitrite transporter
D1814_14635	ENOG4105ETT	transcriptional Regulator, LysR family
D1814_14650	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
D1814_14655	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
D1814_14660	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D1814_14665	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D1814_14670	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
D1814_14675	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D1814_14680	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D1814_14685	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D1814_14730	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D1814_14735	ENOG4105BZS	acriflavin resistance protein
D1814_14760	ENOG4105PGM	cation diffusion facilitator family transporter
D1814_14770	ENOG4105DVT	helicase
D1814_14775	ENOG41072GX	Peptidase M22 Glycoprotease
D1814_14790	ENOG410832A	alpha/beta hydrolase fold
D1814_14795	ENOG4105CEY	Amp-dependent synthetase and ligase
D1814_14800	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
D1814_14805	ENOG4105VNG	YcgL domain-containing protein
D1814_14815	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
D1814_14820	ENOG4108ZZ3	UPF0260 protein
D1814_14830	ENOG4108428	Inherit from COG: -acetyltransferase
D1814_14835	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
D1814_14840	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D1814_14845	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
D1814_14890	ENOG4108UH6	UPF0754 membrane protein
D1814_14900	ENOG4105D8T	Acyltransferase
D1814_14925	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1814_14975	ENOG4105BZU	Histidine kinase
D1814_14980	ENOG4105CRW	Short chain fatty acid transporter
D1814_14985	ENOG4105DKW	ABC transporter
D1814_14990	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D1814_15015	ENOG4105CPQ	Dehydrogenase
D1814_15020	ENOG4108Z6Z	Transcriptional regulator
D1814_15040	ENOG4108Z7F	N-acetyltransferase
D1814_15060	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D1814_15075	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1814_15085	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
D1814_15120	ENOG4105MP9	class II Aldolase
D1814_15125	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
D1814_15145	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D1814_15150	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D1814_15155	ENOG4108S3P	Sporulation domain protein
D1814_15160	ENOG4105E96	Colicin v production protein
D1814_15165	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D1814_15175	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
D1814_15200	ENOG4108R4R	Iron-regulated virulence regulatory protein
D1814_15215	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D1814_15235	ENOG4105KVH	Transcriptional regulator
D1814_15250	ENOG4107S78	Band 7 protein
D1814_15260	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D1814_15265	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1814_15270	ENOG4105C8N	cysteinyl-tRNA synthetase
D1814_15275	ENOG4105E0K	tonB-dependent siderophore receptor
D1814_15285	ENOG4105E9H	Lytic Murein transglycosylase
D1814_15290	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D1814_15295	ENOG4105D1A	Methyltransferase
D1814_15305	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D1814_15310	ENOG4105D1F	ATP-binding protein
D1814_15315	ENOG4105DHP	deoxycytidine triphosphate deaminase
D1814_15320	ENOG4105C8P	)-transporter
D1814_15360	ENOG4105C4R	Atp-dependent dna helicase
D1814_15380	ENOG4106V8H	Nucleoid-associated protein
D1814_15395	ENOG4105BZU	Histidine kinase
D1814_15400	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1814_15415	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1814_15420	ENOG4108I6A	alcohol dehydrogenase
D1814_15430	ENOG4108W5M	transcriptional regulator
D1814_15445	ENOG4108K8S	endonuclease I
D1814_15460	ENOG4105BZU	Histidine kinase
D1814_15475	ENOG4105EIG	urea carboxylase-associated protein 1
D1814_15500	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D1814_15505	ENOG4105EB3	Histidine kinase
D1814_15525	ENOG4105K3G	Periplasmic Protein
D1814_15540	ENOG4105CA9	Pyruvate kinase
D1814_15545	ENOG4106KNT	transcriptional regulator
D1814_15550	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
D1814_15555	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D1814_15560	ENOG4105C01	Dihydroxy-acid dehydratase
D1814_15565	ENOG4105CHC	glucokinase (EC 2.7.1.2)
D1814_15570	ENOG4108UHU	Aldolase
D1814_15575	ENOG4105DSB	aldose 1-epimerase
D1814_15580	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1814_15585	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
D1814_15590	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D1814_15600	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D1814_15605	ENOG4105E0X	reductase
D1814_15625	ENOG4105BZG	amino acid carrier protein
D1814_15640	ENOG4105VUT	cytoplasmic protein
D1814_15690	ENOG4105BZU	Histidine kinase
D1814_15700	ENOG4105BZU	Histidine kinase
D1814_15710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1814_15720	ENOG4105DUM	transcriptional regulator, lysR family
D1814_15730	ENOG41082SX	arsR family transcriptional regulator
D1814_15745	ENOG4105CVI	Transcriptional regulator
D1814_15765	ENOG4105BZU	Histidine kinase
D1814_15770	ENOG4108IQE	Amp-dependent synthetase and ligase
D1814_15780	ENOG4105DSY	exodeoxyribonuclease V, gamma
D1814_15785	ENOG4107QKA	exodeoxyribonuclease V beta
D1814_15790	ENOG4107QYX	exodeoxyribonuclease v alpha
D1814_15800	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D1814_15825	ENOG4108VX5	3-methyladenine DNA glycosylase
D1814_15840	ENOG4107B57	rieske 2fe-2S domain-containing protein
D1814_15845	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D1814_15885	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
D1814_15905	ENOG4108VW6	Pfam:UPF0157
D1814_15920	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D1814_15925	ENOG4105EG6	Saccharopine dehydrogenase
D1814_16000	ENOG4105D06	uba thif-type nad fad binding protein
D1814_16005	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D1814_16010	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D1814_16015	ENOG4105M00	molybdopterin converting factor, subunit 1
D1814_16020	ENOG4108ZAF	Molybdopterin
D1814_16030	ENOG4105E0C	molybdate abc transporter
D1814_16035	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
D1814_16040	ENOG4105D4P	Coproporphyrinogen iii oxidase
D1814_16070	ENOG4105C1G	acyl-Coa dehydrogenase
D1814_16080	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
D1814_16095	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
D1814_16100	ENOG4105BZU	Histidine kinase
D1814_16105	ENOG4105K5B	UPF0225 protein
D1814_16135	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
D1814_16140	ENOG4105DK2	UPF0207 protein
D1814_16145	ENOG4105CHM	Aminotransferase
D1814_16170	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D1814_16175	ENOG4108UKZ	OsmC family
D1814_16180	ENOG4105QNR	S1 RNA binding domain protein
D1814_16185	ENOG4105E7W	lamb ycsf family protein
D1814_16190	ENOG4105P4J	Allophanate hydrolase, subunit 1
D1814_16195	ENOG4107R7A	Allophanate hydrolase subunit 2
D1814_16205	ENOG41090R7	Ferric uptake
D1814_16210	ENOG4108NVR	Methyl-accepting chemotaxis
D1814_16215	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
D1814_16225	ENOG4105EV9	Alpha Beta Hydrolase
D1814_16230	ENOG4108SAU	DNA-binding protein H-ns
D1814_16235	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
D1814_16240	ENOG4105BZJ	Electron transfer flavoprotein
D1814_16245	ENOG4105C10	Electron transfer flavoprotein
D1814_16280	ENOG4105FTV	AraC Family Transcriptional Regulator
D1814_16285	ENOG4105CSU	acyl-Coa dehydrogenase
D1814_16290	ENOG4105CHR	reductase
D1814_16295	ENOG4105CHR	reductase
D1814_16300	ENOG4108UPT	UPF0178 protein
D1814_16310	ENOG4105CGF	Aromatic amino acid aminotransferase
D1814_16325	ENOG4105C28	cystathionine
D1814_16335	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
D1814_16360	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D1814_16370	ENOG4105JAB	phenazine biosynthesis protein, phzf family
D1814_16470	ENOG4105C6T	cysteine synthase
D1814_16490	ENOG4107QI1	Mate efflux family protein
D1814_16495	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D1814_16505	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D1814_16515	ENOG4105C3Q	Glycosyl transferase, family 2
D1814_16520	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
D1814_16525	ENOG4105DBI	uridine monophosphokinase
D1814_16530	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
D1814_16535	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
D1814_16550	ENOG4107QPN	acyl-Coa dehydrogenase
D1814_16560	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D1814_16565	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D1814_16585	ENOG4105CS1	NAD(P)H quinone oxidoreductase
D1814_16590	ENOG4105K89	arsenate reductase
D1814_16600	ENOG4105ERG	peptidase m48, ste24p
D1814_16610	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1814_16620	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D1814_16625	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D1814_16630	ENOG4105C8V	SAICAR synthetase
D1814_16640	ENOG4105BZU	Histidine kinase
D1814_16655	ENOG4105XPH	Ferredoxin
D1814_16660	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D1814_16665	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D1814_16670	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D1814_16675	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1814_16680	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D1814_16685	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D1814_16690	ENOG4105CAT	Cytidine monophosphate kinase
D1814_16695	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D1814_16700	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D1814_16715	ENOG4105CFV	Tetratricopeptide repeat protein
D1814_16720	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
D1814_16725	ENOG4105DCF	alanine dehydrogenase
D1814_16730	ENOG4105EW9	transcriptional regulator AsnC family
D1814_16735	ENOG4105CNU	cell division protein FtsK
D1814_16745	ENOG4105D1H	recombination factor protein RarA
D1814_16750	ENOG4105WMR	Protein CrcB homolog
D1814_16755	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D1814_16775	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D1814_16790	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
D1814_16795	ENOG4108MN8	Membrane
D1814_16830	ENOG4105C2I	pirin domain protein
D1814_16835	ENOG4105WH1	Two component transcriptional regulator luxr family
D1814_16840	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D1814_16920	ENOG4108HJ1	Uncharacterized conserved protein (DUF2303)
D1814_16925	ENOG4105H40	
D1814_16935	ENOG4108R7K	Metal Dependent Phosphohydrolase
D1814_17105	ENOG4106IUH	DTW domain containing protein
D1814_17110	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
D1814_17115	ENOG4105KHC	sulfurtransferase
D1814_17120	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D1814_17125	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
D1814_17145	ENOG4105D78	K07001 NTE family protein
D1814_17150	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
D1814_17155	ENOG4105Q9Y	Universal stress protein
D1814_17160	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D1814_17185	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
D1814_17200	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D1814_17215	ENOG4108UQY	Iron-storage protein
D1814_17220	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D1814_17225	ENOG4105CBC	glutamate synthase
D1814_17235	ENOG41081QV	Universal stress protein
D1814_17245	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1814_17275	ENOG4108WBH	protein TIM barrel
D1814_17280	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1814_17285	ENOG4105CEY	Amp-dependent synthetase and ligase
D1814_17290	ENOG4105DUU	IucA IucC family protein
D1814_17310	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
D1814_17315	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1814_17320	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1814_17325	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1814_17335	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
D1814_17340	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
D1814_17350	ENOG4105C5H	ABC transporter
D1814_17360	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
D1814_17365	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D1814_17370	ENOG4105C7I	Dehydrogenase
D1814_17385	ENOG4105D25	secreted protein
D1814_17400	ENOG4105CD8	aminopeptidase N
D1814_17405	ENOG4105DFD	Na H antiporter
D1814_17410	ENOG4105C8J	)-transporter
D1814_17415	ENOG4105CN1	protease
D1814_17420	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
D1814_17430	ENOG4108ZGC	gaf domain protein
D1814_17440	ENOG4105C5R	Aminotransferase
D1814_17445	ENOG4108Z0R	Transferase
D1814_17450	ENOG4105C29	acyl-CoA thioesterase
D1814_17460	ENOG4105D6S	protein involved in catabolism of external DNA
D1814_17465	ENOG4105C7S	Dehydrogenase
D1814_17470	ENOG4105CPP	Dehydrogenase, E1 component
D1814_17480	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1814_17485	ENOG4105CGY	Dna recombination protein
D1814_17505	ENOG4105EJQ	L-serine dehydratase
D1814_17510	ENOG4107R11	Transcriptional regulator
D1814_17525	ENOG4105F04	LysR family Transcriptional regulator
D1814_17530	ENOG4105D6N	CoA-transferase, subunit a
D1814_17540	ENOG4105C1J	atp-dependent rna helicase
D1814_17580	ENOG4105C72	UPF0176 protein
D1814_17590	ENOG4105BZU	Histidine kinase
D1814_17610	ENOG4105CTQ	phosphohexokinase
D1814_17615	ENOG4108VAC	response regulator
D1814_17620	ENOG4108HRK	Histidine kinase
D1814_17640	ENOG4105E4C	Lytic transglycosylase catalytic
D1814_17650	ENOG4106V8H	Nucleoid-associated protein
D1814_17655	ENOG4105PAN	UPF0352 protein
D1814_17660	ENOG4105E68	Sulfatase
D1814_17665	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
D1814_17670	ENOG4105DHI	Methyltransferase
D1814_17675	ENOG4105E39	Enoyl-CoA hydratase
D1814_17680	ENOG4105C1G	acyl-Coa dehydrogenase
D1814_17690	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D1814_17695	ENOG4108V06	Glutathione peroxidase
D1814_17700	ENOG4105C5I	Dehydrogenase
D1814_17705	ENOG4106371	Methyltransferase
D1814_17710	ENOG4107QNR	UPF0135 protein
D1814_17725	ENOG4105ERU	peptidase
D1814_17730	ENOG4107SQI	penicillin amidase
D1814_17735	ENOG4108M0H	Extracellular lipase
D1814_17740	ENOG4105UBK	short-chain dehydrogenase reductase
D1814_17745	ENOG4105CX6	glutaminyL-tRNA synthetase
D1814_17750	ENOG4105ETE	Transcriptional regulator (LacI family
D1814_17765	ENOG4108IUK	alpha amylase, catalytic
D1814_17785	ENOG4108NRW	Phospholipase, patatin family
D1814_17800	ENOG4105QV4	Tryptophan halogenase
D1814_17815	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D1814_17820	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D1814_17825	ENOG4105C7S	Dehydrogenase
D1814_17830	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D1814_17835	ENOG4105E33	succinate dehydrogenase
D1814_17840	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D1814_17845	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
D1814_17850	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
D1814_17855	ENOG4105BZN	citrate synthase
D1814_17870	ENOG4107QKV	phosphomannomutase
D1814_17880	ENOG4105CHF	Glutathione S-transferase
D1814_17885	ENOG4105CUZ	uba thif-type nad fad binding protein
D1814_17900	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
D1814_17910	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D1814_17915	ENOG4105W49	UPF0434 protein
D1814_17920	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D1814_17925	ENOG4105BZ1	(ABC) transporter
D1814_17940	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D1814_17945	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
D1814_17950	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
D1814_17955	ENOG4105EXN	Sulfate transport protein CysZ
D1814_17985	ENOG410822N	TonB family
D1814_18070	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
D1814_18135	ENOG4107RRE	RNA-directed DNA polymerase
D1814_18175	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
D1814_18185	ENOG4105CK7	Sodium proline symporter
D1814_18200	ENOG4108KP7	hydrolase
D1814_18235	ENOG4105BZU	Histidine kinase
D1814_18250	ENOG4105CP7	Triose-phosphate isomerase
D1814_18255	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
D1814_18260	ENOG4105EEI	dihydropteroate synthase
D1814_18265	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D1814_18270	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
D1814_18275	ENOG4105HBR	Rna-binding protein
D1814_18285	ENOG4105DAN	ATP-dependent protease
D1814_18295	ENOG4105C8T	Leucyl-tRNA synthetase
D1814_18300	ENOG4108U2H	Rare lipoprotein B
D1814_18305	ENOG4105DJF	DNA polymerase III, delta' subunit
D1814_18310	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D1814_18315	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D1814_18320	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D1814_18325	ENOG4105CJN	penicillin-binding protein
D1814_18330	ENOG4105CNI	cell division protein FtsW
D1814_18335	ENOG4105K6T	rare lipoprotein A
D1814_18340	ENOG4105DZ1	carboxypeptidase
D1814_18345	ENOG4108Z43	UPF0250 protein
D1814_18350	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D1814_18355	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D1814_18360	ENOG4105HDK	L-asparaginase
D1814_18370	ENOG41069NU	Nitroreductase
D1814_18385	ENOG4105D07	Signal peptide peptidase, SppA
D1814_18390	ENOG4105GPY	SprT protein
D1814_18395	ENOG4105PQ6	UPF0208 membrane protein
D1814_18400	ENOG4105C3M	thioredoxin reductase
D1814_18405	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D1814_18410	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
D1814_18415	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D1814_18420	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1814_18425	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
D1814_18430	ENOG4105VEQ	Cold shock protein
D1814_18435	ENOG4105E9K	Isocitrate dehydrogenase
D1814_18440	ENOG4108R99	pseudouridine synthase
D1814_18445	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D1814_18450	ENOG41075W9	High frequency lysogenization protein HflD homolog
D1814_18455	ENOG4107QTF	adenylosuccinate lyase
D1814_18465	ENOG4105EZE	Cupin 4 family protein
D1814_18495	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D1814_18515	ENOG4107RDJ	Sulfotransferase
D1814_18525	ENOG4105C94	Transporter
D1814_18535	ENOG4105VDB	UPF0125 protein
D1814_18540	ENOG4108Z1B	Cyclase dehydrase
D1814_18545	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D1814_18550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1814_18565	ENOG4105CJ1	ABC, transporter
D1814_18580	ENOG4105E0K	tonB-dependent siderophore receptor
D1814_18595	ENOG4105BZU	Histidine kinase
D1814_18600	ENOG4105EJC	lysr family transcriptional regulator
D1814_18625	ENOG4105E0K	tonB-dependent siderophore receptor
D1814_18660	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
D1814_18675	ENOG4105VNH	ABC transporter solute-binding protein
D1814_18685	ENOG4107QN2	dihydrolipoyl dehydrogenase
D1814_18690	ENOG4105D05	Receptor
D1814_18705	ENOG4105CCT	upf0313 protein
D1814_18750	ENOG4105D3R	alkyl hydroperoxide reductase
D1814_18775	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
D1814_18785	ENOG4105FE9	pseudouridine synthase
D1814_18790	ENOG4105BZU	Histidine kinase
D1814_18790	ENOG4105BZU	Histidine kinase
D1814_18795	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D1814_18800	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D1814_18805	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D1814_18810	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D1814_18815	ENOG4105CHV	Transcription elongation factor NusA
D1814_18820	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
D1814_18825	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1814_18830	ENOG4105BZU	Histidine kinase
D1814_18850	ENOG4105KZX	Pterin carbinolamine dehydratase
D1814_18855	ENOG4105D05	Receptor
D1814_18860	ENOG4105D8X	mechanosensitive ion channel
D1814_18880	ENOG4105CQB	FAD linked oxidase domain protein
D1814_18885	ENOG4105CKI	cobalamin synthesis protein
D1814_18895	ENOG4105N80	Ferric uptake regulator, Fur family
D1814_18905	ENOG4105DEI	Mannitol dehydrogenase
D1814_18915	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
D1814_18920	ENOG4105DKT	Transcriptional regulator
D1814_18940	ENOG4105CSU	acyl-Coa dehydrogenase
D1814_18945	ENOG4105CHU	acetyl-coa acetyltransferase
D1814_18955	ENOG4108J2P	Alpha beta hydrolase fold
D1814_18960	ENOG4105CHR	reductase
D1814_18985	ENOG4105BZU	Histidine kinase
D1814_19000	ENOG4105F8V	Hydrolase, tatD family
D1814_19005	ENOG4107QRG	dna polymerase iii
D1814_19010	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
D1814_19015	ENOG4105HHA	aminodeoxychorismate lyase
D1814_19020	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
D1814_19025	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1814_19030	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1814_19035	ENOG4105CHR	reductase
D1814_19040	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D1814_19045	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1814_19050	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D1814_19055	ENOG4105VGS	50s ribosomal protein l32
D1814_19060	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
D1814_19065	ENOG4108UHJ	MAF-like protein
D1814_19070	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D1814_19075	ENOG4105EI2	Pseudouridine synthase
D1814_19080	ENOG4105C03	ribonuclease
D1814_19095	ENOG4107YB6	acetyltransferase, (GNAT) family
D1814_19100	ENOG4105JQN	Transcriptional regulator
D1814_19120	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
D1814_19125	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
D1814_19130	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D1814_19140	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
D1814_19145	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D1814_19150	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
D1814_19160	ENOG4105CK2	sodium dicarboxylate symporter
D1814_19165	ENOG4105D60	lipoprotein releasing system transmembrane protein
D1814_19170	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1814_19175	ENOG4108M8H	domain protein
D1814_19205	ENOG4107RZZ	dna polymerase iii epsilon subunit
D1814_19210	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D1814_19215	ENOG4108JA1	polyketide synthase
D1814_19220	ENOG4105DR4	Methyltransferase
D1814_19235	ENOG4105CQ7	ATP-dependent helicase
D1814_19270	ENOG4105D44	asparaginase
D1814_19275	ENOG4105BZU	Histidine kinase
D1814_19280	ENOG4105CJB	Exodeoxyribonuclease I
D1814_19290	ENOG4105BZU	Histidine kinase
D1814_19305	ENOG4105CHU	acetyl-coa acetyltransferase
D1814_19310	ENOG4108Z6Z	Transcriptional regulator
D1814_19315	ENOG4105C1G	acyl-Coa dehydrogenase
D1814_19320	ENOG4107QX3	carboxylase
D1814_19325	ENOG4108UKI	Enoyl-CoA hydratase
D1814_19335	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
D1814_19355	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)