locus-tag	class	description
AltI4_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AltI4_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AltI4_00030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AltI4_00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AltI4_00070	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AltI4_00080	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AltI4_00090	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AltI4_00110	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
AltI4_00130	ENOG4106RE7	Cytochrome
AltI4_00140	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AltI4_00150	ENOG4105C2M	dna polymerase I
AltI4_00160	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AltI4_00170	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AltI4_00190	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AltI4_00240	ENOG4105C1A	potassium transporter peripheral membrane
AltI4_00250	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AltI4_00270	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AltI4_00280	ENOG4108WZM	domain protein
AltI4_00290	ENOG4105C79	DNA protecting protein DprA
AltI4_00310	ENOG4108RPN	Protein smg homolog
AltI4_00330	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AltI4_00340	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AltI4_00350	ENOG4105EIF	outer membrane protein W
AltI4_00370	ENOG4105E2X	shikimate dehydrogenase
AltI4_00380	ENOG4108Z0R	Transferase
AltI4_00410	ENOG4105C0B	DNA polymerase III (alpha subunit)
AltI4_00470	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AltI4_00480	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AltI4_00490	ENOG4105W5Q	DNA repair protein (RadC
AltI4_00530	ENOG4105E3R	(LipO)protein
AltI4_00540	ENOG4105KDC	50s ribosomal protein l28
AltI4_00550	ENOG4105W0E	50S ribosomal protein L33
AltI4_00570	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AltI4_00580	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AltI4_00590	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AltI4_00600	ENOG4105DKP	glycosyl transferase, family 9
AltI4_00630	ENOG4105BZU	Histidine kinase
AltI4_00640	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AltI4_00650	ENOG4105CPQ	Dehydrogenase
AltI4_00660	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AltI4_00670	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
AltI4_00690	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AltI4_00700	ENOG4105W0Z	cytoplasmic protein
AltI4_00710	ENOG4105C4R	Atp-dependent dna helicase
AltI4_00720	ENOG4105BZU	Histidine kinase
AltI4_00730	ENOG4105MPD	Cytochrome
AltI4_00760	ENOG4105VZ1	Replication Protein
AltI4_00850	ENOG4108KU3	Integrase
AltI4_00870	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AltI4_01000	ENOG4105D2S	major facilitator superfamily
AltI4_01020	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AltI4_01150	ENOG4105E2B	Taurine dioxygenase
AltI4_01170	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AltI4_01200	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
AltI4_01210	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AltI4_01280	ENOG4105FUY	alpha subunit
AltI4_01300	ENOG4105CF7	AraC family transcriptional regulator
AltI4_01310	ENOG4107RTG	Major Facilitator superfamily
AltI4_01350	ENOG41060NJ	transcriptional regulator
AltI4_01360	ENOG4105CNT	hydrolase family 2
AltI4_01410	ENOG4105M6F	mutator MutT protein
AltI4_01420	ENOG4105ETE	Transcriptional regulator (LacI family
AltI4_01430	ENOG4105D05	Receptor
AltI4_01450	ENOG4108RXX	maleylacetoacetate isomerase
AltI4_01520	ENOG4105ERH	Fumarylacetoacetate hydrolase
AltI4_01550	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
AltI4_01560	ENOG4105CI2	imidazolone-5-propionate hydrolase
AltI4_01570	ENOG4105DUM	transcriptional regulator, lysR family
AltI4_01610	ENOG4105DHQ	Histidine kinase
AltI4_01620	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
AltI4_01700	ENOG4105CM6	amino acid regulated cytosolic protein
AltI4_01730	ENOG4108KPZ	tonB-dependent Receptor
AltI4_01770	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
AltI4_01780	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AltI4_01800	ENOG4105CE1	Ferrous iron transport protein b
AltI4_01820	ENOG4105ECF	c-methyltransferase
AltI4_01840	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AltI4_01850	ENOG4106CJB	Phospholipase Carboxylesterase
AltI4_01860	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AltI4_01870	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AltI4_01880	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AltI4_01890	ENOG4105KME	endoribonuclease L-psp
AltI4_01900	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AltI4_01940	ENOG4105CB5	ATP-dependent DNA helicase recG
AltI4_01950	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AltI4_01960	ENOG4105EHV	domain protein
AltI4_01970	ENOG4105EBR	Carboxylesterase
AltI4_01980	ENOG4105CBX	hi0933 family
AltI4_02000	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AltI4_02010	ENOG4107SET	aldo keto reductase
AltI4_02020	ENOG4107RBB	ABC transporter, permease
AltI4_02040	ENOG4105C19	ABC transporter
AltI4_02060	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AltI4_02070	ENOG4105C6F	GntR Family Transcriptional Regulator
AltI4_02110	ENOG4105GZI	Transcriptional regulator
AltI4_02120	ENOG4106UX7	integral membrane protein
AltI4_02150	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AltI4_02170	ENOG4107RAN	Peptidase, M16
AltI4_02180	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AltI4_02190	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
AltI4_02220	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AltI4_02230	ENOG4108UZ3	Transporter
AltI4_02320	ENOG4105F04	LysR family Transcriptional regulator
AltI4_02350	ENOG4105D4T	Citrate transporter
AltI4_02360	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AltI4_02370	ENOG4105D05	Receptor
AltI4_02420	ENOG4105BZU	Histidine kinase
AltI4_02440	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
AltI4_02460	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AltI4_02470	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AltI4_02480	ENOG4108JJ9	ABC, transporter
AltI4_02490	ENOG4108JJ8	(ABC) transporter
AltI4_02520	ENOG4106B0W	Curli production assembly transport component CsgG
AltI4_02550	ENOG4107Y60	(LipO)protein
AltI4_02570	ENOG4108VCT	Sulfite exporter TauE/SafE
AltI4_02590	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AltI4_02620	ENOG4105CT4	transporter
AltI4_02640	ENOG4108NVR	Methyl-accepting chemotaxis
AltI4_02650	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AltI4_02670	ENOG4105KT5	UmuD protein
AltI4_02700	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AltI4_02730	ENOG4105US7	Histidine kinase
AltI4_02760	ENOG4108YZA	Nitrogen regulatory protein pii
AltI4_02770	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
AltI4_02780	ENOG410620I	Diguanylate cyclase
AltI4_02790	ENOG4107QHF	type ii secretion system protein e
AltI4_02800	ENOG4108MAJ	Membrane
AltI4_02810	ENOG4108S4H	thioesterase Superfamily protein
AltI4_02850	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AltI4_02860	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AltI4_02870	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AltI4_02880	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AltI4_02890	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AltI4_02900	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AltI4_02910	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AltI4_02920	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AltI4_02930	ENOG41083MP	50s ribosomal protein l29
AltI4_02940	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AltI4_02950	ENOG4105DQ4	alcohol dehydrogenase
AltI4_02960	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AltI4_03020	ENOG4105E7A	Glutamine amidotransferase
AltI4_03040	ENOG4105DGW	oligopeptidase A
AltI4_03060	ENOG4107F58	2'-5' rna ligase
AltI4_03070	ENOG4105CQ7	ATP-dependent helicase
AltI4_03090	ENOG4105CVE	Lytic murein transglycosylase
AltI4_03140	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AltI4_03160	ENOG4105BZ4	penicillin-binding protein
AltI4_03190	ENOG4105CKW	Inner membrane protein yedI
AltI4_03210	ENOG4108YZA	Nitrogen regulatory protein pii
AltI4_03230	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AltI4_03240	ENOG4105EZR	dyp-type peroxidase family protein
AltI4_03250	ENOG41063Z6	transcriptional regulator, lysR family
AltI4_03260	ENOG4105D0M	Protease HtpX homolog
AltI4_03300	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AltI4_03310	ENOG4105CXT	aspartate transcarbamylase
AltI4_03330	ENOG4105BZU	Histidine kinase
AltI4_03340	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AltI4_03360	ENOG4105BZU	Histidine kinase
AltI4_03380	ENOG4105C26	Dehydrogenase
AltI4_03400	ENOG4105C8Y	Acetylornithine aminotransferase
AltI4_03430	ENOG4105C31	Tryptophanyl-tRNA synthetase
AltI4_03440	ENOG4105DJV	ribulose-phosphate 3-epimerase
AltI4_03480	ENOG4105DFE	Dna adenine methylase
AltI4_03500	ENOG4105D49	3-dehydroquinate synthase
AltI4_03510	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AltI4_03520	ENOG4105E4G	Type IV pilus
AltI4_03570	ENOG4108JQC	penicillin-binding protein 1A
AltI4_03580	ENOG4107R1I	NAD-dependent malic enzyme
AltI4_03660	ENOG4105BZU	Histidine kinase
AltI4_03690	ENOG4107QZM	n-acetylglutamate synthase
AltI4_03700	ENOG4105CH7	arginosuccinase
AltI4_03710	ENOG4105CDH	Citrulline--aspartate ligase
AltI4_03730	ENOG4105CAS	nag kinase
AltI4_03740	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AltI4_03750	ENOG4108Z5K	methylglyoxal synthase
AltI4_03780	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AltI4_03790	ENOG4105E0F	Histidine kinase
AltI4_03800	ENOG4108EUD	Lysophospholipase
AltI4_03810	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AltI4_03820	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AltI4_03830	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AltI4_03850	ENOG4107YZP	Rhodanese domain protein
AltI4_03860	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AltI4_03870	ENOG41063SB	peptidase
AltI4_03880	ENOG4105PXI	polysaccharide deacetylase
AltI4_03890	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AltI4_03900	ENOG4107RDJ	Sulfotransferase
AltI4_03920	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
AltI4_03940	ENOG4105DJ4	phosphatidylserine decarboxylase
AltI4_03950	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AltI4_03960	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AltI4_03990	ENOG4105C7K	acetolactate synthase
AltI4_04000	ENOG4108ZP8	Acetolactate synthase small subunit
AltI4_04030	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AltI4_04040	ENOG410887T	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AltI4_04050	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AltI4_04070	ENOG4105F8V	Hydrolase, tatD family
AltI4_04080	ENOG4105BZU	Histidine kinase
AltI4_04090	ENOG4105D52	delta-aminolevulinic acid dehydratase
AltI4_04100	ENOG4105C9X	ppx gppa phosphatase
AltI4_04110	ENOG4105C1J	atp-dependent rna helicase
AltI4_04120	ENOG4105K63	Thioredoxin
AltI4_04130	ENOG4105CFP	Peptidase U32
AltI4_04150	ENOG4105CH2	amidohydrolase
AltI4_04160	ENOG4105BZU	Histidine kinase
AltI4_04170	ENOG4105DUM	transcriptional regulator, lysR family
AltI4_04180	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AltI4_04190	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AltI4_04220	ENOG4105D8V	Glucose sorbosone dehydrogenase
AltI4_04230	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AltI4_04250	ENOG4107QR8	Thioredoxin
AltI4_04280	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AltI4_04290	ENOG4105C26	Dehydrogenase
AltI4_04340	ENOG4105D29	Helix-turn-helix type 11 domain protein
AltI4_04350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AltI4_04360	ENOG4107S6Z	Na H antiporter
AltI4_04440	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
AltI4_04460	ENOG4105EHZ	conserved protein UCP016719
AltI4_04470	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AltI4_04480	ENOG4107RJ1	sodium solute
AltI4_04490	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AltI4_04510	ENOG4105RD7	BadF BadG BcrA BcrD
AltI4_04690	ENOG4105D4A	Cell wall formation (By similarity)
AltI4_04700	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AltI4_04710	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AltI4_04720	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AltI4_04750	ENOG4105WH1	Two component transcriptional regulator luxr family
AltI4_04770	ENOG4107QPV	Serine Threonine protein kinase
AltI4_04820	ENOG4108N5B	2-phosphosulfolactate phosphatase
AltI4_04840	ENOG4105CPC	Aldo Keto reductase
AltI4_04870	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AltI4_04890	ENOG4107Y3V	-acetyltransferase
AltI4_04920	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AltI4_04940	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AltI4_04950	ENOG4105BZU	Histidine kinase
AltI4_04970	ENOG4107QN1	sodium solute
AltI4_04980	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AltI4_05020	ENOG4108N3W	hemolysin secretion protein
AltI4_05080	ENOG4107VAM	peptidase, m28
AltI4_05100	ENOG4105D9N	nucleoside
AltI4_05110	ENOG4105DBI	uridine monophosphokinase
AltI4_05140	ENOG4108KPZ	tonB-dependent Receptor
AltI4_05150	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AltI4_05160	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AltI4_05170	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AltI4_05180	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AltI4_05200	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AltI4_05210	ENOG4105CH5	extracellular solute-binding protein, family 7
AltI4_05220	ENOG4105RKW	reductase (By
AltI4_05230	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AltI4_05240	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AltI4_05250	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AltI4_05260	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AltI4_05270	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AltI4_05280	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AltI4_05290	ENOG4105CJ2	(LipO)protein
AltI4_05340	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AltI4_05370	ENOG4105NBK	UPF0345 protein
AltI4_05380	ENOG4105EFZ	amidohydrolase
AltI4_05400	ENOG4105BZU	Histidine kinase
AltI4_05410	ENOG4105KWG	Pfam:DUF1696
AltI4_05440	ENOG4105K4T	epimerase
AltI4_05460	ENOG4109015	Biopolymer transport protein exbD tolR
AltI4_05480	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AltI4_05510	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AltI4_05530	ENOG410822N	TonB family
AltI4_05540	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AltI4_05570	ENOG4105C8J	)-transporter
AltI4_05580	ENOG4108535	NAD dependent epimerase/dehydratase family
AltI4_05620	ENOG4105CUY	Mechanosensitive ion channel
AltI4_05630	ENOG4106HNH	Acyl-transferase
AltI4_05640	ENOG4106HNH	Acyl-transferase
AltI4_05650	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AltI4_05660	ENOG4107SET	aldo keto reductase
AltI4_05710	ENOG4105QV4	Tryptophan halogenase
AltI4_05770	ENOG4105E08	Glycoside hydrolase, family 9
AltI4_05790	ENOG4105C93	Xylose Isomerase
AltI4_05800	ENOG4105CMG	Carbohydrate kinase
AltI4_05810	ENOG4105T16	Transcriptional regulator (AraC family)
AltI4_05840	ENOG4105ETT	transcriptional Regulator, LysR family
AltI4_05870	ENOG4108K2F	hydrolase Family 5
AltI4_05880	ENOG4106HBX	Transcriptional Regulator AraC Family
AltI4_05890	ENOG4105CNT	hydrolase family 2
AltI4_05920	ENOG4105DT9	hydrolase family 43
AltI4_05950	ENOG4107RNH	Outer membrane receptor FepA
AltI4_05990	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AltI4_06020	ENOG41087YS	Phage shock protein A
AltI4_06070	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AltI4_06080	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AltI4_06090	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AltI4_06110	ENOG4105BZU	Histidine kinase
AltI4_06130	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AltI4_06150	ENOG4105BZU	Histidine kinase
AltI4_06170	ENOG4105EJ2	Transcriptional regulator
AltI4_06180	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AltI4_06240	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AltI4_06260	ENOG4105CHU	acetyl-coa acetyltransferase
AltI4_06270	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AltI4_06290	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
AltI4_06310	ENOG4105EAH	synthase
AltI4_06320	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AltI4_06330	ENOG4105K46	50S ribosomal protein l27
AltI4_06340	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AltI4_06370	ENOG4105BZU	Histidine kinase
AltI4_06380	ENOG4108W5X	Transcriptional Regulator, LuxR family
AltI4_06390	ENOG4107QZV	Type I secretion membrane fusion protein
AltI4_06410	ENOG4105CDV	Ompa motb domain protein
AltI4_06430	ENOG4105VNT	transposase (IS4 family) protein
AltI4_06440	ENOG4105BZU	Histidine kinase
AltI4_06450	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AltI4_06460	ENOG4105BZU	Histidine kinase
AltI4_06480	ENOG4108K5P	(LipO)protein
AltI4_06490	ENOG4108UM1	dedA family
AltI4_06500	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AltI4_06510	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AltI4_06520	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AltI4_06540	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AltI4_06550	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AltI4_06590	ENOG4106MWK	domain protein
AltI4_06620	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AltI4_06640	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AltI4_06650	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AltI4_06660	ENOG4105HF0	Membrane
AltI4_06670	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AltI4_06680	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AltI4_06690	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AltI4_06700	ENOG4105BZU	Histidine kinase
AltI4_06740	ENOG4105D3G	Pseudouridine synthase
AltI4_06750	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AltI4_06760	ENOG4108IAB	Phoh family
AltI4_06780	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AltI4_06790	ENOG4105C1J	atp-dependent rna helicase
AltI4_06840	ENOG4105DFG	type I secretion outer membrane protein
AltI4_06850	ENOG41087AY	ADP-Ribose pyrophosphatase
AltI4_06860	ENOG4108SX3	cytoplasmic protein
AltI4_06870	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AltI4_06880	ENOG4105IPS	esterase
AltI4_06890	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AltI4_06940	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AltI4_06950	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AltI4_06960	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AltI4_06970	ENOG4105UGU	tonB-dependent Receptor
AltI4_06990	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AltI4_07000	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AltI4_07010	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AltI4_07020	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AltI4_07030	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AltI4_07040	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AltI4_07050	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AltI4_07060	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AltI4_07070	ENOG4105VPB	50S ribosomal protein L30
AltI4_07080	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AltI4_07090	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AltI4_07100	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AltI4_07110	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AltI4_07120	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AltI4_07130	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AltI4_07140	ENOG4108ZT0	50S ribosomal protein l17
AltI4_07430	ENOG4105ECJ	Glycosyl Transferase
AltI4_07440	ENOG4105CKK	Glycosyl transferase, family 2
AltI4_07460	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AltI4_07500	ENOG4105WH1	Two component transcriptional regulator luxr family
AltI4_07510	ENOG4105WH1	Two component transcriptional regulator luxr family
AltI4_07550	ENOG4105C30	Nad-dependent epimerase dehydratase
AltI4_07600	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AltI4_07610	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AltI4_07620	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AltI4_07640	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AltI4_07680	ENOG4105CQ2	DNA polymerase
AltI4_07700	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_07760	ENOG4105BZU	Histidine kinase
AltI4_07780	ENOG4105BZU	Histidine kinase
AltI4_07820	ENOG4105BZU	Histidine kinase
AltI4_07840	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AltI4_07850	ENOG4105HF0	Membrane
AltI4_07870	ENOG4105DND	Transcriptional regulator
AltI4_07890	ENOG4105DVH	amino acid
AltI4_07920	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AltI4_07930	ENOG4105E53	ec 3.2.1.28
AltI4_08010	ENOG4105DZ2	Transcriptional regulator
AltI4_08020	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
AltI4_08040	ENOG4105CF7	AraC family transcriptional regulator
AltI4_08050	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AltI4_08070	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AltI4_08100	ENOG4107ZSV	Receptor
AltI4_08110	ENOG4105F52	Transcriptional regulator
AltI4_08140	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AltI4_08150	ENOG4105EQ2	LysR family Transcriptional regulator
AltI4_08160	ENOG4108M15	ABC transporter
AltI4_08180	ENOG4105CPN	adenine deaminase
AltI4_08190	ENOG4105BZU	Histidine kinase
AltI4_08200	ENOG4108S01	response regulator
AltI4_08210	ENOG4105EGS	Mechanosensitive ion channel
AltI4_08220	ENOG4105JVQ	RNA Polymerase
AltI4_08280	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AltI4_08320	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AltI4_08340	ENOG4108Q9V	regulatoR
AltI4_08350	ENOG4105ENE	Histidine kinase
AltI4_08380	ENOG4105CYM	Glutathione S-transferase
AltI4_08390	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AltI4_08470	ENOG4105NA0	Transcriptional regulator
AltI4_08600	ENOG4105I03	Flagellin
AltI4_08620	ENOG4105CYM	Glutathione S-transferase
AltI4_08650	ENOG4105KVH	Transcriptional regulator
AltI4_08670	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AltI4_08770	ENOG4108K5H	permease YjgP YjgQ family protein
AltI4_08780	ENOG4108M8S	permease YjgP YjgQ family protein
AltI4_08790	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AltI4_08800	ENOG4105MYG	DNA polymerase iii, chi subunit
AltI4_08810	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AltI4_08820	ENOG4107R3J	Transporter
AltI4_08830	ENOG4105D9P	serine threonine protein kinase
AltI4_08850	ENOG4105PE1	Receptor
AltI4_08860	ENOG4105CA0	peroxidase
AltI4_08910	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AltI4_08920	ENOG4105BZU	Histidine kinase
AltI4_08940	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AltI4_08950	ENOG4107QIJ	Aconitate hydratase 2
AltI4_08960	ENOG4105WD1	Membrane
AltI4_08970	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AltI4_08980	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AltI4_09000	ENOG41090JD	Blue (Type 1) copper domain protein
AltI4_09010	ENOG4105C9Q	fumarate hydratase class II
AltI4_09080	ENOG4108VEQ	Superoxide dismutase
AltI4_09150	ENOG4105BZU	Histidine kinase
AltI4_09180	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
AltI4_09200	ENOG4108K0D	peptidase, M48
AltI4_09210	ENOG4108M3P	Membrane
AltI4_09220	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
AltI4_09230	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AltI4_09240	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AltI4_09250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_09260	ENOG4105CUX	Signal transduction histidine kinase
AltI4_09280	ENOG4105C5F	glutamine synthetase
AltI4_09290	ENOG4105CI3	gtp-binding protein typa
AltI4_09310	ENOG4105C87	Aminotransferase class I and II
AltI4_09450	ENOG4108IUM	Glycogen debranching enzyme
AltI4_09470	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AltI4_09500	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AltI4_09520	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AltI4_09530	ENOG4105DR5	peptidase
AltI4_09540	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AltI4_09580	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AltI4_09600	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AltI4_09660	ENOG4105CHR	reductase
AltI4_09680	ENOG4105JQN	Transcriptional regulator
AltI4_09690	ENOG4105EMU	Dehydrogenase
AltI4_09710	ENOG4105CHR	reductase
AltI4_09730	ENOG4105CHR	reductase
AltI4_09780	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AltI4_09850	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AltI4_09870	ENOG4105CHU	acetyl-coa acetyltransferase
AltI4_09880	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AltI4_09890	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AltI4_09900	ENOG4105C10	Electron transfer flavoprotein
AltI4_09910	ENOG4105BZJ	Electron transfer flavoprotein
AltI4_09930	ENOG4105CC9	acyl-Coa dehydrogenase
AltI4_09940	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_09980	ENOG4105CHU	acetyl-coa acetyltransferase
AltI4_10020	ENOG4105BZ8	glutamate synthase
AltI4_10030	ENOG4105CBC	glutamate synthase
AltI4_10040	ENOG4105BZU	Histidine kinase
AltI4_10080	ENOG4105C7F	AcnD-accessory protein PrpF
AltI4_10090	ENOG4108I0Z	Aconitate hydratase
AltI4_10100	ENOG4105BZN	citrate synthase
AltI4_10110	ENOG4105CR4	methylisocitrate lyase
AltI4_10140	ENOG4105W4M	Transport-associated protein
AltI4_10150	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AltI4_10160	ENOG41082RQ	UPF0102 protein
AltI4_10170	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AltI4_10180	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AltI4_10210	ENOG4105E3Q	saccharopine dehydrogenase
AltI4_10270	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AltI4_10290	ENOG4105BZU	Histidine kinase
AltI4_10300	ENOG4105BZU	Histidine kinase
AltI4_10310	ENOG4105BZU	Histidine kinase
AltI4_10340	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AltI4_10350	ENOG4105D98	threonine synthase
AltI4_10360	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AltI4_10380	ENOG4107QP8	phosphohexose isomerase
AltI4_10390	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AltI4_10400	ENOG4105D1Q	UPF0246 protein
AltI4_10410	ENOG4105C5Z	peptidase
AltI4_10450	ENOG4108VIA	integral membrane protein
AltI4_10460	ENOG4105II7	pyrroline-5-carboxylate reductase
AltI4_10470	ENOG4105DFA	alanine racemase domain protein
AltI4_10480	ENOG4105CZX	twitching motility protein
AltI4_10490	ENOG4105CZX	twitching motility protein
AltI4_10510	ENOG4108J2P	Alpha beta hydrolase fold
AltI4_10540	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AltI4_10550	ENOG4108UJU	UPF0301 protein
AltI4_10560	ENOG4105D7Z	glutathione synthase
AltI4_10570	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AltI4_10620	ENOG4108N3W	hemolysin secretion protein
AltI4_10630	ENOG4108VYJ	response regulator receiver protein
AltI4_10640	ENOG4105CBS	Chea signal transduction histidine kinase
AltI4_10650	ENOG4108V3W	Chemotaxis protein, CheW
AltI4_10660	ENOG4107SDU	Methyl-accepting chemotaxis
AltI4_10670	ENOG4105BZU	Histidine kinase
AltI4_10680	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AltI4_10700	ENOG4105BZU	Histidine kinase
AltI4_10710	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_10720	ENOG4105BZU	Histidine kinase
AltI4_10750	ENOG4105EHV	domain protein
AltI4_10790	ENOG4108IJF	Heavy metal efflux pump, CzcA
AltI4_10800	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AltI4_10870	ENOG4105DKW	ABC transporter
AltI4_10880	ENOG4108V6E	Cell division protein mraZ
AltI4_10890	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AltI4_10900	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AltI4_10910	ENOG4105CJN	penicillin-binding protein
AltI4_10920	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AltI4_10930	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AltI4_10940	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AltI4_10950	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AltI4_10960	ENOG4105CNI	cell division protein FtsW
AltI4_10970	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AltI4_10980	ENOG4105DFU	Cell wall formation (By similarity)
AltI4_10990	ENOG4105CPF	Cell wall formation (By similarity)
AltI4_11000	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AltI4_11010	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AltI4_11020	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AltI4_11030	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AltI4_11040	ENOG4105E4C	Lytic transglycosylase catalytic
AltI4_11050	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AltI4_11060	ENOG4105M6F	mutator MutT protein
AltI4_11080	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_11090	ENOG4108V3W	Chemotaxis protein, CheW
AltI4_11100	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AltI4_11120	ENOG4105BZU	Histidine kinase
AltI4_11130	ENOG4108VYJ	response regulator receiver protein
AltI4_11140	ENOG4105CBS	Chea signal transduction histidine kinase
AltI4_11160	ENOG4107QJE	Chromosome Partitioning Protein
AltI4_11170	ENOG4108VYJ	response regulator receiver protein
AltI4_11180	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_11190	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_11200	ENOG4105C6F	GntR Family Transcriptional Regulator
AltI4_11210	ENOG4105C6F	GntR Family Transcriptional Regulator
AltI4_11270	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AltI4_11280	ENOG4105D2N	Aldolase
AltI4_11290	ENOG4108UHU	Aldolase
AltI4_11300	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AltI4_11310	ENOG4105DPW	Major facilitator superfamily MFS_1
AltI4_11330	ENOG4105EY3	heparinase II III family protein
AltI4_11350	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AltI4_11430	ENOG4105EGI	Transcriptional regulator
AltI4_11450	ENOG4105CSA	Coproporphyrinogen iii oxidase
AltI4_11460	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AltI4_11470	ENOG4105C1J	atp-dependent rna helicase
AltI4_11480	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AltI4_11510	ENOG4105CPI	Metal Dependent Phosphohydrolase
AltI4_11520	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AltI4_11530	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AltI4_11540	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AltI4_11550	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AltI4_11570	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AltI4_11580	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AltI4_11590	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AltI4_11610	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AltI4_11640	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AltI4_11650	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AltI4_11660	ENOG41060IM	Heme exporter protein
AltI4_11670	ENOG4105X3C	heme exporter protein
AltI4_11680	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AltI4_11690	ENOG4105DA4	cytochrome c-type biogenesis protein
AltI4_11700	ENOG4107QX9	Thiol disulfide interChange protein
AltI4_11710	ENOG4105KWW	Biogenesis protein
AltI4_11730	ENOG410903C	(LipO)protein
AltI4_11740	ENOG4105CMR	udp-glucose 4-epimerase
AltI4_11760	ENOG4105DUX	Transporter
AltI4_11790	ENOG4107V1M	polysaccharide export protein
AltI4_11810	ENOG4105ESV	Glycosyl transferase, family 4
AltI4_11820	ENOG4105K64	Glycosyl transferase, family 2
AltI4_11840	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AltI4_11850	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AltI4_11870	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AltI4_11880	ENOG4105D7W	serine acetyltransferase
AltI4_11890	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AltI4_11900	ENOG4105C3J	Cysteine desulfurase
AltI4_11920	ENOG4105C3K	feS assembly ATPase SufC
AltI4_11940	ENOG4105C9B	Cysteine desulfurase
AltI4_11950	ENOG4108Z4V	iron-sulfur cluster assembly
AltI4_11970	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AltI4_11980	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AltI4_11990	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AltI4_12010	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AltI4_12020	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AltI4_12030	ENOG4105CUT	histidyl-tRNA synthetase
AltI4_12040	ENOG4105N21	Membrane
AltI4_12050	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AltI4_12060	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AltI4_12080	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AltI4_12090	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AltI4_12100	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AltI4_12120	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_12130	ENOG4105DGU	Histone deacetylase
AltI4_12140	ENOG4105HDD	phospholipase
AltI4_12150	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AltI4_12160	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AltI4_12170	ENOG4108R96	Methyltransferase, YaeB family
AltI4_12180	ENOG4105DA5	(ABC) transporter
AltI4_12230	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AltI4_12240	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AltI4_12250	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AltI4_12260	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AltI4_12270	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AltI4_12280	ENOG4105K70	DNA-binding protein
AltI4_12290	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AltI4_12370	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AltI4_12380	ENOG4105CJW	magnesium transporter
AltI4_12390	ENOG4105CJR	Integral membrane protein (MviN
AltI4_12400	ENOG4105DTN	riboflavin biosynthesis protein ribF
AltI4_12410	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AltI4_12420	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AltI4_12430	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AltI4_12440	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AltI4_12510	ENOG4108VWS	Yaeq family
AltI4_12570	ENOG4108VAU	general secretion pathway protein G
AltI4_12630	ENOG4105F5W	AtP-binding protein
AltI4_12640	ENOG4105D70	Integrase catalytic subunit
AltI4_12690	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AltI4_12700	ENOG4108YZA	Nitrogen regulatory protein pii
AltI4_12710	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AltI4_12730	ENOG4105Y75	tpr repeat protein
AltI4_12740	ENOG4108F01	MaoC domain protein
AltI4_12760	ENOG4108IYU	L-aspartate oxidase
AltI4_12770	ENOG4105EMN	RNA polymerase sigma factor
AltI4_12810	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AltI4_12820	ENOG4105C3F	Signal peptidase i
AltI4_12830	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AltI4_12840	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AltI4_12850	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AltI4_12860	ENOG4105EYA	deoxyribonuclease
AltI4_12880	ENOG4105EAC	phosphoserine phosphatase
AltI4_12930	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AltI4_12950	ENOG4105C5H	ABC transporter
AltI4_12960	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AltI4_12970	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AltI4_12980	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AltI4_12990	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AltI4_13020	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AltI4_13030	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AltI4_13040	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AltI4_13050	ENOG4108ZAI	phosphatidylglycerophosphatase a
AltI4_13070	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AltI4_13080	ENOG4105CTB	Polyprenyl synthetase
AltI4_13090	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AltI4_13100	ENOG4105E14	MotA TolQ exbB proton channel
AltI4_13110	ENOG4106VK6	Flagellar motor protein
AltI4_13120	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AltI4_13150	ENOG4105EMU	Dehydrogenase
AltI4_13180	ENOG4105K6V	RNA polymerase
AltI4_13190	ENOG4108NIX	Factor ChrR
AltI4_13200	ENOG4105BZU	Histidine kinase
AltI4_13210	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AltI4_13220	ENOG4105C34	Pseudouridine synthase
AltI4_13230	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AltI4_13240	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AltI4_13270	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AltI4_13280	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_13290	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_13320	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_13340	ENOG4105E18	UPF0276 protein
AltI4_13360	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AltI4_13370	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AltI4_13380	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AltI4_13390	ENOG4105IQ5	FAD linked oxidase domain protein
AltI4_13400	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AltI4_13410	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AltI4_13420	ENOG4107KJX	Transcriptional regulator
AltI4_13460	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AltI4_13470	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AltI4_13540	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AltI4_13550	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AltI4_13560	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AltI4_13570	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AltI4_13580	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AltI4_13590	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AltI4_13600	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AltI4_13610	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AltI4_13710	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
AltI4_13780	ENOG4105BZU	Histidine kinase
AltI4_13800	ENOG4105DY2	Paraquat-inducible protein b
AltI4_13810	ENOG4105F1S	paraquat-inducible protein a
AltI4_13820	ENOG4105C5S	asparaginyl-tRNA synthetase
AltI4_13900	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AltI4_13910	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AltI4_13930	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AltI4_13940	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AltI4_13950	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
AltI4_13960	ENOG4105KJF	protein tyrosine phosphatase
AltI4_13970	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AltI4_13980	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
AltI4_13990	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
AltI4_14010	ENOG4105VRT	cytoplasmic protein
AltI4_14020	ENOG4108JJ7	ABC transporter
AltI4_14030	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AltI4_14050	ENOG4105BZU	Histidine kinase
AltI4_14060	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AltI4_14080	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AltI4_14090	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
AltI4_14110	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AltI4_14120	ENOG4105CXK	mandelate racemase muconate lactonizing
AltI4_14160	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AltI4_14170	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AltI4_14180	ENOG4105CD3	dihydroorotase
AltI4_14190	ENOG4105BZU	Histidine kinase
AltI4_14220	ENOG4108I0Y	(ABC) transporter
AltI4_14230	ENOG4105CV6	ABC transporter, permease
AltI4_14260	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
AltI4_14310	ENOG4107S9F	NmrA family
AltI4_14320	ENOG4105KVH	Transcriptional regulator
AltI4_14350	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
AltI4_14360	ENOG4105ECP	epimerase
AltI4_14370	ENOG4105DSF	transport protein
AltI4_14400	ENOG4105IFJ	Histidine kinase
AltI4_14410	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AltI4_14430	ENOG4105K9H	YciI-like protein
AltI4_14440	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AltI4_14450	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AltI4_14460	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AltI4_14470	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AltI4_14480	ENOG4108EFP	Anthranilate synthase component II
AltI4_14490	ENOG4105CRQ	synthase (Component I)
AltI4_14500	ENOG4105DB7	PHP domain protein
AltI4_14510	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AltI4_14530	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AltI4_14540	ENOG4105FE9	pseudouridine synthase
AltI4_14550	ENOG4105CNM	Receptor
AltI4_14590	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AltI4_14660	ENOG4105HHM	rdd domain containing protein
AltI4_14700	ENOG4108V06	Glutathione peroxidase
AltI4_14720	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AltI4_14740	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AltI4_14750	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AltI4_14770	ENOG4105CIG	ABC transporter
AltI4_14780	ENOG4105BZU	Histidine kinase
AltI4_14790	ENOG4105F8J	Adenylate Guanylate cyclase
AltI4_14810	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AltI4_14840	ENOG4105DWV	Homoserine O-trans-acetylase
AltI4_14850	ENOG4105CY2	Citrate transporter
AltI4_14920	ENOG4105BZU	Histidine kinase
AltI4_14930	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AltI4_14940	ENOG4105CFG	Acts as a chaperone (By similarity)
AltI4_14950	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AltI4_14970	ENOG4105BZU	Histidine kinase
AltI4_14980	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AltI4_15010	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AltI4_15020	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AltI4_15030	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AltI4_15040	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AltI4_15060	ENOG4105I4A	GCN5-related N-acetyltransferase
AltI4_15080	ENOG4105CX8	fg-gap repeat protein
AltI4_15100	ENOG4105CHH	sulfate transporter
AltI4_15110	ENOG4107B2H	carbonic anhydrase
AltI4_15150	ENOG4105EMN	RNA polymerase sigma factor
AltI4_15160	ENOG410822N	TonB family
AltI4_15170	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AltI4_15180	ENOG4105K3M	)-transporter
AltI4_15190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AltI4_15270	ENOG4108ZNX	Heat shock protein
AltI4_15280	ENOG4105CI2	imidazolone-5-propionate hydrolase
AltI4_15290	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AltI4_15300	ENOG4108JU5	Magnesium and cobalt efflux protein
AltI4_15310	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AltI4_15320	ENOG4105C9A	Phoh family
AltI4_15330	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AltI4_15340	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AltI4_15360	ENOG4105BZG	amino acid carrier protein
AltI4_15380	ENOG4105C3G	gtp-binding protein
AltI4_15390	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AltI4_15400	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AltI4_15430	ENOG4105BZU	Histidine kinase
AltI4_15460	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AltI4_15470	ENOG4105BZU	Histidine kinase
AltI4_15490	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AltI4_15500	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AltI4_15520	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AltI4_15530	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AltI4_15540	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AltI4_15550	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AltI4_15560	ENOG4108YY7	Invasion gene expression up-regulator SirB
AltI4_15570	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AltI4_15590	ENOG4105ETT	transcriptional Regulator, LysR family
AltI4_15620	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
AltI4_15630	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AltI4_15650	ENOG4105E3S	small subunit
AltI4_15660	ENOG4105DPX	Hydrogenase, large subunit
AltI4_15670	ENOG4105C8H	hydrogenase maturation protein Hypf
AltI4_15680	ENOG4105E3S	small subunit
AltI4_15690	ENOG4105DPX	Hydrogenase, large subunit
AltI4_15710	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AltI4_15730	ENOG4105X9Y	Hydrogenase assembly chaperone hypC hupF
AltI4_15740	ENOG4105YYZ	Hydrogenase expression formation protein
AltI4_15760	ENOG4107UY0	rubredoxin
AltI4_15770	ENOG410631X	Hydrogenase expression formation protein
AltI4_15830	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
AltI4_15840	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AltI4_15850	ENOG4105CQS	hydrogenase expression formation protein HypD
AltI4_15860	ENOG4105C45	hydrogenase expression formation protein (HypE)
AltI4_15960	ENOG4105DVT	helicase
AltI4_15970	ENOG41072GX	Peptidase M22 Glycoprotease
AltI4_16010	ENOG4105CEY	Amp-dependent synthetase and ligase
AltI4_16020	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AltI4_16030	ENOG4105VNG	YcgL domain-containing protein
AltI4_16040	ENOG4105CVE	Lytic murein transglycosylase
AltI4_16050	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AltI4_16060	ENOG4108ZZ3	UPF0260 protein
AltI4_16080	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AltI4_16090	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AltI4_16100	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
AltI4_16170	ENOG4106MP8	UPF0754 membrane protein
AltI4_16200	ENOG4105DHI	Methyltransferase
AltI4_16260	ENOG4107T0K	Adenylate cyclase
AltI4_16280	ENOG4108Q5F	Tetr family transcriptional regulator
AltI4_16290	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AltI4_16330	ENOG4108BPE	-transporting atpase
AltI4_16390	ENOG4105K4U	addiction module toxin, RelE StbE family
AltI4_16440	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AltI4_16460	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AltI4_16510	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AltI4_16520	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AltI4_16530	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AltI4_16540	ENOG4108S3P	Sporulation domain protein
AltI4_16550	ENOG4105E96	Colicin v production protein
AltI4_16560	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AltI4_16580	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AltI4_16590	ENOG4107SDU	Methyl-accepting chemotaxis
AltI4_16630	ENOG4105G6Z	alkaline phosphatase
AltI4_16640	ENOG4105G6Z	alkaline phosphatase
AltI4_16650	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AltI4_16660	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AltI4_16670	ENOG4105C8N	cysteinyl-tRNA synthetase
AltI4_16680	ENOG4105EKQ	RNA-directed DNA polymerase
AltI4_16690	ENOG4105CQZ	Histidine kinase
AltI4_16730	ENOG4105C8P	)-transporter
AltI4_16740	ENOG4107R1I	NAD-dependent malic enzyme
AltI4_16770	ENOG4105E9H	Lytic Murein transglycosylase
AltI4_16780	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AltI4_16790	ENOG4105D1A	Methyltransferase
AltI4_16800	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AltI4_16810	ENOG4105D1F	ATP-binding protein
AltI4_16820	ENOG4105DHP	deoxycytidine triphosphate deaminase
AltI4_16860	ENOG4108RWN	rrna methyltransferase
AltI4_16870	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AltI4_16880	ENOG4108Z4U	Ferredoxin
AltI4_16890	ENOG4105DZ0	fad dependent oxidoreductase
AltI4_16910	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AltI4_16930	ENOG4108VKG	metal-dependent hydrolase
AltI4_16940	ENOG4105BZU	Histidine kinase
AltI4_16980	ENOG4105C5H	ABC transporter
AltI4_17010	ENOG4105CEY	Amp-dependent synthetase and ligase
AltI4_17020	ENOG4108ZX5	transcriptional regulator
AltI4_17030	ENOG4105DAA	L-lactate
AltI4_17050	ENOG4105C5X	domain protein
AltI4_17080	ENOG4105F27	Major Facilitator
AltI4_17100	ENOG4105D6J	arsenicaL-resistance protein
AltI4_17110	ENOG4105CAU	Arsenical resistance protein, ArsH
AltI4_17130	ENOG41082YX	Transcriptional regulator, arsr family
AltI4_17200	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AltI4_17220	ENOG4105DUM	transcriptional regulator, lysR family
AltI4_17230	ENOG4105JSC	dimethylmenaquinone methyltransferase
AltI4_17250	ENOG4105KHM	amidohydrolase 2
AltI4_17260	ENOG4105GAK	amidohydrolase 2
AltI4_17280	ENOG4105CPC	Aldo Keto reductase
AltI4_17300	ENOG4107ZSV	Receptor
AltI4_17320	ENOG4105D2S	major facilitator superfamily
AltI4_17330	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AltI4_17380	ENOG4105CXG	d-lactate dehydrogenase
AltI4_17400	ENOG4105K3G	Periplasmic Protein
AltI4_17430	ENOG410903C	(LipO)protein
AltI4_17510	ENOG4105BZU	Histidine kinase
AltI4_17530	ENOG4105BZU	Histidine kinase
AltI4_17550	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_17580	ENOG41080HT	Transcriptional regulator, arsr family
AltI4_17610	ENOG4105CVI	Transcriptional regulator
AltI4_17640	ENOG4105BZU	Histidine kinase
AltI4_17650	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
AltI4_17670	ENOG4108IQE	Amp-dependent synthetase and ligase
AltI4_17710	ENOG4105DSY	exodeoxyribonuclease V, gamma
AltI4_17720	ENOG4107QKA	exodeoxyribonuclease V beta
AltI4_17730	ENOG4107QYX	exodeoxyribonuclease v alpha
AltI4_17780	ENOG4105D06	uba thif-type nad fad binding protein
AltI4_17790	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AltI4_17800	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AltI4_17810	ENOG4105M00	molybdopterin converting factor, subunit 1
AltI4_17820	ENOG4108ZAF	Molybdopterin
AltI4_17830	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AltI4_17840	ENOG4105E0C	molybdate abc transporter
AltI4_17850	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AltI4_17860	ENOG4105D4P	Coproporphyrinogen iii oxidase
AltI4_17900	ENOG4105BZU	Histidine kinase
AltI4_17930	ENOG4105D8X	mechanosensitive ion channel
AltI4_17940	ENOG4105KZX	Pterin carbinolamine dehydratase
AltI4_17960	ENOG4105BZU	Histidine kinase
AltI4_17970	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AltI4_17980	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AltI4_17990	ENOG4105CHV	Transcription elongation factor NusA
AltI4_18000	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AltI4_18010	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AltI4_18020	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AltI4_18030	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AltI4_18040	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_18080	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AltI4_18110	ENOG4105D3R	alkyl hydroperoxide reductase
AltI4_18120	ENOG4108JU3	Alkyl hydroperoxide reductase
AltI4_18160	ENOG4105CCT	upf0313 protein
AltI4_18200	ENOG4107S8C	mandelate racemase muconate lactonizing
AltI4_18220	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AltI4_18250	ENOG4106BRA	Membrane
AltI4_18260	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AltI4_18270	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AltI4_18290	ENOG4108NRW	Phospholipase, patatin family
AltI4_18330	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AltI4_18340	ENOG4105CPN	adenine deaminase
AltI4_18370	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_18430	ENOG4107R3N	Filamentation induced by cAMP protein fic
AltI4_18450	ENOG4105ESI	atpase involved in dna repair
AltI4_18530	ENOG4108C33	Resolvase
AltI4_18570	ENOG4105VV5	Plasmid stabilization system
AltI4_18650	ENOG4105F5W	AtP-binding protein
AltI4_18660	ENOG4105D70	Integrase catalytic subunit
AltI4_18860	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AltI4_18880	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AltI4_18890	ENOG4108Z1B	Cyclase dehydrase
AltI4_18900	ENOG4105VDB	UPF0125 protein
AltI4_18920	ENOG4105C94	Transporter
AltI4_18940	ENOG4107RDJ	Sulfotransferase
AltI4_18950	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AltI4_18960	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AltI4_18990	ENOG4105BZU	Histidine kinase
AltI4_19020	ENOG4105CQB	FAD linked oxidase domain protein
AltI4_19050	ENOG4105EZE	Cupin 4 family protein
AltI4_19070	ENOG4107QTF	adenylosuccinate lyase
AltI4_19080	ENOG41075W9	High frequency lysogenization protein HflD homolog
AltI4_19090	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AltI4_19100	ENOG4108R99	pseudouridine synthase
AltI4_19110	ENOG4105E9K	Isocitrate dehydrogenase
AltI4_19130	ENOG4105VEQ	Cold shock protein
AltI4_19140	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AltI4_19150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AltI4_19160	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AltI4_19170	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AltI4_19180	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AltI4_19190	ENOG4105C3M	thioredoxin reductase
AltI4_19210	ENOG4105GPY	SprT protein
AltI4_19220	ENOG4105D07	Signal peptide peptidase, SppA
AltI4_19250	ENOG41069NU	Nitroreductase
AltI4_19260	ENOG4105CA9	Pyruvate kinase
AltI4_19270	ENOG4106KNT	transcriptional regulator
AltI4_19280	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AltI4_19290	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AltI4_19300	ENOG4105C01	Dihydroxy-acid dehydratase
AltI4_19310	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AltI4_19320	ENOG4108UHU	Aldolase
AltI4_19340	ENOG4105DSB	aldose 1-epimerase
AltI4_19360	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
AltI4_19370	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AltI4_19390	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AltI4_19400	ENOG4105E0X	reductase
AltI4_19440	ENOG4105BZG	amino acid carrier protein
AltI4_19460	ENOG4105VUT	cytoplasmic protein
AltI4_19500	ENOG4105HDK	L-asparaginase
AltI4_19550	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AltI4_19560	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AltI4_19570	ENOG4108Z43	UPF0250 protein
AltI4_19580	ENOG4105DZ1	carboxypeptidase
AltI4_19590	ENOG4105K6T	rare lipoprotein A
AltI4_19600	ENOG4105CNI	cell division protein FtsW
AltI4_19610	ENOG4105CJN	penicillin-binding protein
AltI4_19630	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AltI4_19640	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AltI4_19670	ENOG4105C8T	Leucyl-tRNA synthetase
AltI4_19690	ENOG4105DAN	ATP-dependent protease
AltI4_19710	ENOG4105HBR	Rna-binding protein
AltI4_19720	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AltI4_19730	ENOG4105EEI	dihydropteroate synthase
AltI4_19740	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AltI4_19750	ENOG4105CP7	Triose-phosphate isomerase
AltI4_19800	ENOG4105CBD	Diacylglycerol kinase
AltI4_19830	ENOG4105CK7	Sodium proline symporter
AltI4_19850	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AltI4_19880	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AltI4_19950	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AltI4_19960	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AltI4_19970	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AltI4_19990	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AltI4_20000	ENOG4105BZ1	(ABC) transporter
AltI4_20010	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AltI4_20020	ENOG4105W49	UPF0434 protein
AltI4_20030	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AltI4_20050	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AltI4_20090	ENOG4105CUZ	uba thif-type nad fad binding protein
AltI4_20100	ENOG4105D5U	fad dependent oxidoreductase
AltI4_20110	ENOG4105CHF	Glutathione S-transferase
AltI4_20120	ENOG4105EUB	pirin domain protein
AltI4_20130	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AltI4_20140	ENOG4107QKV	phosphomannomutase
AltI4_20160	ENOG4105BZN	citrate synthase
AltI4_20170	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AltI4_20180	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AltI4_20190	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AltI4_20200	ENOG4105E33	succinate dehydrogenase
AltI4_20210	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AltI4_20220	ENOG4105C7S	Dehydrogenase
AltI4_20230	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AltI4_20240	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AltI4_20310	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AltI4_20360	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AltI4_20370	ENOG4105ETE	Transcriptional regulator (LacI family
AltI4_20380	ENOG4105CX6	glutaminyL-tRNA synthetase
AltI4_20390	ENOG4105UBK	short-chain dehydrogenase reductase
AltI4_20400	ENOG4108M0H	Extracellular lipase
AltI4_20410	ENOG4105ERU	peptidase
AltI4_20430	ENOG4107QNR	UPF0135 protein
AltI4_20440	ENOG4106371	Methyltransferase
AltI4_20450	ENOG4105C5I	Dehydrogenase
AltI4_20460	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AltI4_20480	ENOG4105C26	Dehydrogenase
AltI4_20490	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_20500	ENOG4105E39	Enoyl-CoA hydratase
AltI4_20510	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AltI4_20520	ENOG4105E68	Sulfatase
AltI4_20530	ENOG4105PAN	UPF0352 protein
AltI4_20540	ENOG4106V8H	Nucleoid-associated protein
AltI4_20600	ENOG4108HRK	Histidine kinase
AltI4_20610	ENOG4108VAC	response regulator
AltI4_20630	ENOG4105CTQ	phosphohexokinase
AltI4_20670	ENOG4105BZU	Histidine kinase
AltI4_20690	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AltI4_20710	ENOG4105C72	UPF0176 protein
AltI4_20740	ENOG4105C1J	atp-dependent rna helicase
AltI4_20760	ENOG4105D6N	CoA-transferase, subunit a
AltI4_20770	ENOG4105F04	LysR family Transcriptional regulator
AltI4_20780	ENOG4105DIJ	Phosphoethanolamine transferase
AltI4_20820	ENOG4107R11	Transcriptional regulator
AltI4_20910	ENOG4105F5W	AtP-binding protein
AltI4_20920	ENOG4105D70	Integrase catalytic subunit
AltI4_21140	ENOG4105CNT	hydrolase family 2
AltI4_21320	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AltI4_21390	ENOG4105EJQ	L-serine dehydratase
AltI4_21410	ENOG4105CRQ	synthase (Component I)
AltI4_21440	ENOG4105CGY	Dna recombination protein
AltI4_21450	ENOG4105BZU	Histidine kinase
AltI4_21480	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
AltI4_21490	ENOG4107R0V	Pyruvate dehydrogenase
AltI4_21500	ENOG4105CPP	Dehydrogenase, E1 component
AltI4_21510	ENOG4105C7S	Dehydrogenase
AltI4_21520	ENOG4105D6S	protein involved in catabolism of external DNA
AltI4_21540	ENOG4105C29	acyl-CoA thioesterase
AltI4_21550	ENOG4105C5R	Aminotransferase
AltI4_21560	ENOG4108JIC	nucleoside recognition domain protein
AltI4_21580	ENOG4108ZGC	gaf domain protein
AltI4_21600	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
AltI4_21610	ENOG4105CN1	protease
AltI4_21620	ENOG4105C8J	)-transporter
AltI4_21630	ENOG4105DFD	Na H antiporter
AltI4_21640	ENOG4105CD8	aminopeptidase N
AltI4_21660	ENOG4105D25	secreted protein
AltI4_21690	ENOG4105C7I	Dehydrogenase
AltI4_21700	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AltI4_21710	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AltI4_21730	ENOG4105C5H	ABC transporter
AltI4_21750	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
AltI4_21760	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AltI4_21780	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AltI4_21790	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AltI4_21800	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AltI4_21850	ENOG4108WUH	Transcriptional regulator, TetR family
AltI4_21860	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AltI4_21920	ENOG4105C2F	Histidine kinase
AltI4_21930	ENOG4108NEV	two component transcriptional regulator, LytTR family
AltI4_22010	ENOG4105C3F	Signal peptidase i
AltI4_22020	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
AltI4_22030	ENOG4108M8H	domain protein
AltI4_22040	ENOG4107SFI	Major Facilitator superfamily
AltI4_22050	ENOG41080IJ	Diacylglycerol kinase
AltI4_22060	ENOG4105D64	Mechanosensitive ion channel
AltI4_22100	ENOG4105CEY	Amp-dependent synthetase and ligase
AltI4_22120	ENOG41081QV	Universal stress protein
AltI4_22130	ENOG4105CBC	glutamate synthase
AltI4_22160	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AltI4_22170	ENOG4108UQY	Iron-storage protein
AltI4_22200	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AltI4_22230	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AltI4_22250	ENOG4105C59	p-type ATPase
AltI4_22280	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AltI4_22290	ENOG4105Q9Y	Universal stress protein
AltI4_22300	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AltI4_22310	ENOG4105D78	K07001 NTE family protein
AltI4_22360	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AltI4_22370	ENOG4105KHC	sulfurtransferase
AltI4_22390	ENOG4108N3W	hemolysin secretion protein
AltI4_22450	ENOG4105D70	Integrase catalytic subunit
AltI4_22460	ENOG4105F5W	AtP-binding protein
AltI4_22550	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AltI4_22560	ENOG4105WH1	Two component transcriptional regulator luxr family
AltI4_22570	ENOG4108MN8	Membrane
AltI4_22580	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
AltI4_22590	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AltI4_22610	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AltI4_22620	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AltI4_22630	ENOG4105WMR	Protein CrcB homolog
AltI4_22640	ENOG4105D1H	recombination factor protein RarA
AltI4_22660	ENOG4105CNU	cell division protein FtsK
AltI4_22670	ENOG4105EW9	transcriptional regulator AsnC family
AltI4_22680	ENOG4105DCF	alanine dehydrogenase
AltI4_22690	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AltI4_22700	ENOG4105CFV	Tetratricopeptide repeat protein
AltI4_22720	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AltI4_22730	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AltI4_22740	ENOG4105CAT	Cytidine monophosphate kinase
AltI4_22760	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AltI4_22770	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AltI4_22780	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AltI4_22790	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AltI4_22800	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AltI4_22810	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AltI4_22820	ENOG4105XPH	Ferredoxin
AltI4_22840	ENOG4105C8V	SAICAR synthetase
AltI4_22850	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AltI4_22860	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AltI4_22880	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AltI4_22930	ENOG4105ERG	peptidase m48, ste24p
AltI4_22940	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AltI4_22950	ENOG4105K89	arsenate reductase
AltI4_22960	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AltI4_22990	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
AltI4_23010	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AltI4_23020	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AltI4_23040	ENOG4107QPN	acyl-Coa dehydrogenase
AltI4_23050	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AltI4_23070	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AltI4_23080	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AltI4_23100	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
AltI4_23110	ENOG4105C3Q	Glycosyl transferase, family 2
AltI4_23130	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AltI4_23140	ENOG4107QI1	Mate efflux family protein
AltI4_23170	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AltI4_23190	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AltI4_23230	ENOG4105C6T	cysteine synthase
AltI4_23320	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
AltI4_23350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AltI4_23360	ENOG4105E39	Enoyl-CoA hydratase
AltI4_23400	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AltI4_23410	ENOG4108IQK	o-acetylhomoserine
AltI4_23440	ENOG4105CGF	Aromatic amino acid aminotransferase
AltI4_23510	ENOG4105C10	Electron transfer flavoprotein
AltI4_23520	ENOG4105BZJ	Electron transfer flavoprotein
AltI4_23530	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AltI4_23550	ENOG4105EV9	Alpha Beta Hydrolase
AltI4_23570	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AltI4_23580	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_23590	ENOG41090R7	Ferric uptake
AltI4_23600	ENOG4105F0I	Aminotransferase
AltI4_23620	ENOG4105P4J	Allophanate hydrolase, subunit 1
AltI4_23630	ENOG4105E7W	lamb ycsf family protein
AltI4_23640	ENOG4105QNR	S1 RNA binding domain protein
AltI4_23650	ENOG4108UKZ	OsmC family
AltI4_23660	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AltI4_23720	ENOG4105CHM	Aminotransferase
AltI4_23730	ENOG4105DK2	UPF0207 protein
AltI4_23740	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AltI4_23760	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AltI4_23800	ENOG4105K5B	UPF0225 protein
AltI4_23920	ENOG4105C6Z	Gluconate
AltI4_23930	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AltI4_23940	ENOG4105DIQ	Transcriptional regulator
AltI4_23950	ENOG4108UVJ	appr-1-p processing domain protein
AltI4_23970	ENOG4105F8V	Hydrolase, tatD family
AltI4_23980	ENOG4107QRG	dna polymerase iii
AltI4_23990	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AltI4_24000	ENOG4105HHA	aminodeoxychorismate lyase
AltI4_24010	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
AltI4_24020	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AltI4_24030	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AltI4_24040	ENOG4105CHR	reductase
AltI4_24050	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AltI4_24060	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AltI4_24070	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AltI4_24080	ENOG4105VGS	50s ribosomal protein l32
AltI4_24090	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AltI4_24100	ENOG4108UHJ	MAF-like protein
AltI4_24120	ENOG4105EI2	Pseudouridine synthase
AltI4_24130	ENOG4105C03	ribonuclease
AltI4_24200	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AltI4_24210	ENOG4105CHF	Glutathione S-transferase
AltI4_24220	ENOG4108VGI	doxx family
AltI4_24230	ENOG4105CC0	LysR family Transcriptional regulator
AltI4_24250	ENOG4105DFD	Na H antiporter
AltI4_24290	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
AltI4_24300	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AltI4_24310	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
AltI4_24340	ENOG4105D60	lipoprotein releasing system transmembrane protein
AltI4_24350	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AltI4_24360	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
AltI4_24390	ENOG4105C9F	isomerase
AltI4_24450	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AltI4_24460	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AltI4_24480	ENOG4108JA1	polyketide synthase
AltI4_24500	ENOG4105DR4	Methyltransferase
AltI4_24530	ENOG4105CQ7	ATP-dependent helicase
AltI4_24570	ENOG4105D44	asparaginase
AltI4_24580	ENOG4105CJB	Exodeoxyribonuclease I
AltI4_24610	ENOG4105CHU	acetyl-coa acetyltransferase
AltI4_24620	ENOG4108Z4X	TRANSCRIPTIONal
AltI4_24630	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_24640	ENOG4107QX3	carboxylase
AltI4_24650	ENOG4108IPT	Naphthoate synthase
AltI4_24670	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AltI4_24730	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AltI4_24780	ENOG4108HU6	Metal dependent phosphohydrolase
AltI4_24790	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AltI4_24830	ENOG4105CGK	Exodeoxyribonuclease III
AltI4_24860	ENOG4105E0F	Histidine kinase
AltI4_24870	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AltI4_24910	ENOG4108UPT	UPF0178 protein
AltI4_24930	ENOG4108UMN	azlc family
AltI4_24950	ENOG4105KD7	acetyltransferase
AltI4_25040	ENOG4108JNI	Alpha beta hydrolase
AltI4_25090	ENOG41068WN	
AltI4_25320	ENOG4105D70	Integrase catalytic subunit
AltI4_25330	ENOG4105F5W	AtP-binding protein
AltI4_25550	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AltI4_25560	ENOG4105D60	lipoprotein releasing system transmembrane protein
AltI4_25580	ENOG4108JA2	transcriptioN-repair coupling factor
AltI4_25600	ENOG4108WBT	adenosyltransferase
AltI4_25620	ENOG4105C8P	)-transporter
AltI4_25630	ENOG4105CUJ	penicillin amidase
AltI4_25640	ENOG4108Z66	YbaK ebsC protein
AltI4_25670	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AltI4_25680	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AltI4_25690	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AltI4_25710	ENOG4105E0K	tonB-dependent siderophore receptor
AltI4_25720	ENOG4105VDW	Csbd family
AltI4_25750	ENOG4105DUM	transcriptional regulator, lysR family
AltI4_25760	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AltI4_25770	ENOG41082NX	50s ribosomal protein l35
AltI4_25780	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AltI4_25790	ENOG4105C22	threonyL-tRNA synthetase
AltI4_25830	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AltI4_25840	ENOG4105DHQ	Histidine kinase
AltI4_25900	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AltI4_25930	ENOG4105CJ2	(LipO)protein
AltI4_25940	ENOG4105C5Q	Transcriptional regulator
AltI4_25950	ENOG4107B2H	carbonic anhydrase
AltI4_25960	ENOG4105CHH	sulfate transporter
AltI4_25990	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AltI4_26000	ENOG4105HF0	Membrane
AltI4_26010	ENOG4105C5R	Aminotransferase
AltI4_26040	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AltI4_26050	ENOG4105C2W	permease
AltI4_26080	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AltI4_26090	ENOG4105C7N	Xanthine uracil vitamin C permease
AltI4_26110	ENOG4108R86	Transcriptional regulator
AltI4_26130	ENOG4105C7W	Xanthine dehydrogenase
AltI4_26170	ENOG4107QUY	Guanine deaminase
AltI4_26190	ENOG4105BZU	Histidine kinase
AltI4_26200	ENOG4105BZU	Histidine kinase
AltI4_26230	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AltI4_26250	ENOG4105D7T	ABC transporter
AltI4_26280	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AltI4_26290	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AltI4_26310	ENOG4105WZK	nitrite reductase NADPH small subunit
AltI4_26320	ENOG4107QZF	nitrite reductase NADPH large subunit
AltI4_26440	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AltI4_26450	ENOG4105BZJ	Electron transfer flavoprotein
AltI4_26460	ENOG4105C10	Electron transfer flavoprotein
AltI4_26470	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AltI4_26480	ENOG4105EW9	transcriptional regulator AsnC family
AltI4_26500	ENOG4108TKH	Nitroreductase
AltI4_26510	ENOG4105EWK	phytoene
AltI4_26530	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_26540	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AltI4_26550	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AltI4_26620	ENOG4105CCU	oxidase (Subunit III)
AltI4_26650	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AltI4_26730	ENOG4105D25	secreted protein
AltI4_26830	ENOG4105C26	Dehydrogenase
AltI4_26860	ENOG4105CHR	reductase
AltI4_26930	ENOG4105IYB	L-carnitine dehydratase bile acid-inducible protein F
AltI4_26940	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_26950	ENOG4105CI0	Citrate lyase
AltI4_26960	ENOG4108M9J	MaoC like domain protein
AltI4_26970	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AltI4_26980	ENOG4105E39	Enoyl-CoA hydratase
AltI4_26990	ENOG4108UKI	Enoyl-CoA hydratase
AltI4_27020	ENOG4108ZX5	transcriptional regulator
AltI4_27040	ENOG4105VCQ	rubredoxin
AltI4_27080	ENOG4107Z7P	Ferredoxin
AltI4_27100	ENOG4107ZSV	Receptor
AltI4_27110	ENOG4105D25	secreted protein
AltI4_27170	ENOG4105KUZ	arsenate reductase
AltI4_27180	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AltI4_27210	ENOG4105K8R	UPF0145 protein
AltI4_27230	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
AltI4_27240	ENOG4105BZU	Histidine kinase
AltI4_27250	ENOG4105VNT	transposase (IS4 family) protein
AltI4_27260	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AltI4_27270	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AltI4_27290	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AltI4_27310	ENOG4105F8C	transglutaminase domain-containing protein
AltI4_27320	ENOG4105C08	Histidine kinase
AltI4_27330	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_27350	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AltI4_27370	ENOG4107RE3	peptidase, S41
AltI4_27470	ENOG4108JJA	ABC, transporter
AltI4_27480	ENOG41063Z6	transcriptional regulator, lysR family
AltI4_27550	ENOG4105D3Q	Sugar transferase
AltI4_27570	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AltI4_27580	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AltI4_27610	ENOG4105E2K	Glycosyl transferase (Group 1
AltI4_27620	ENOG4105CND	Glycosyl transferase, family 2
AltI4_27660	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AltI4_27670	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AltI4_27680	ENOG4108DMA	Nad-dependent epimerase dehydratase
AltI4_27690	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AltI4_27700	ENOG4105UFD	tol-pal system protein YbgF
AltI4_27710	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AltI4_27720	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AltI4_27740	ENOG4105M8F	Biopolymer transport protein exbD tolR
AltI4_27750	ENOG4105E02	MotA TolQ exbB proton channel
AltI4_27760	ENOG4107YD3	Thioesterase
AltI4_27770	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
AltI4_27790	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AltI4_27800	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AltI4_27810	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AltI4_27820	ENOG4108TIT	dATP pyrophosphohydrolase
AltI4_27830	ENOG4105C9M	aspartyl-trna synthetase
AltI4_27860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_27880	ENOG4107WP9	Histidine kinase
AltI4_27920	ENOG4105BZU	Histidine kinase
AltI4_27940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AltI4_27960	ENOG4108ZJT	translation initiation factor, Sui1
AltI4_27970	ENOG4108VYJ	response regulator receiver protein
AltI4_28000	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AltI4_28010	ENOG4105C19	ABC transporter
AltI4_28050	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AltI4_28100	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AltI4_28110	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AltI4_28120	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AltI4_28130	ENOG4105K5M	30s ribosomal protein S16
AltI4_28140	ENOG4105BZ1	(ABC) transporter
AltI4_28160	ENOG4105BZS	acriflavin resistance protein
AltI4_28240	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AltI4_28250	ENOG4106KVJ	cytochrome C assembly protein
AltI4_28260	ENOG4108JU6	CBS domain protein
AltI4_28290	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
AltI4_28300	ENOG4105BZU	Histidine kinase
AltI4_28330	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AltI4_28340	ENOG4105CHU	acetyl-coa acetyltransferase
AltI4_28350	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AltI4_28420	ENOG4105EMN	RNA polymerase sigma factor
AltI4_28440	ENOG4105CK7	Sodium proline symporter
AltI4_28450	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AltI4_28460	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
AltI4_28470	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AltI4_28480	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AltI4_28500	ENOG4105BZU	Histidine kinase
AltI4_28530	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AltI4_28570	ENOG4105QV4	Tryptophan halogenase
AltI4_28610	ENOG4105EKQ	RNA-directed DNA polymerase
AltI4_28620	ENOG4108SDH	ABC, transporter
AltI4_28630	ENOG4108IUW	ABC transporter
AltI4_28670	ENOG4105CAQ	asparagine synthetase
AltI4_28690	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AltI4_28700	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AltI4_28730	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AltI4_28740	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AltI4_28750	ENOG4105C3S	Mate efflux family protein
AltI4_28760	ENOG4105DGN	Electron transport complex
AltI4_28770	ENOG4108R3D	Electron transport complex
AltI4_28790	ENOG4105D6A	Electron transport complex
AltI4_28800	ENOG4108UQQ	Electron transport complex
AltI4_28810	ENOG4105DZB	Electron transport complex
AltI4_28820	ENOG4105CSM	endonuclease III
AltI4_28870	ENOG4108UYE	Lactoylglutathione lyase
AltI4_28880	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AltI4_28890	ENOG4105EIY	sodium-type flagellar protein motY
AltI4_28900	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AltI4_28910	ENOG4107QNK	)-transporter
AltI4_28920	ENOG4105D3R	alkyl hydroperoxide reductase
AltI4_28970	ENOG4105D05	Receptor
AltI4_28980	ENOG4105M2J	Glutaredoxin
AltI4_28990	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AltI4_29000	ENOG4105CYN	Serine protein kinase
AltI4_29010	ENOG4106AKX	UPF0229 protein
AltI4_29020	ENOG4105ED1	spovr family
AltI4_29030	ENOG4105D8G	Major Facilitator superfamily
AltI4_29040	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AltI4_29050	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AltI4_29060	ENOG4108DG9	Smr protein MutS2
AltI4_29100	ENOG4105D9M	gamma-glutamylcysteine synthetase
AltI4_29130	ENOG4108W1A	pseudouridine synthase
AltI4_29140	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AltI4_29150	ENOG4105CRK	lysyL-tRNA synthetase
AltI4_29180	ENOG4105C75	arginyL-tRNA synthetase
AltI4_29190	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AltI4_29280	ENOG4108ESX	Receptor
AltI4_29300	ENOG4108S4H	thioesterase Superfamily protein
AltI4_29330	ENOG410822N	TonB family
AltI4_29340	ENOG4109015	Biopolymer transport protein exbD tolR
AltI4_29400	ENOG4108KPZ	tonB-dependent Receptor
AltI4_29420	ENOG4107RDP	Dehydrogenase
AltI4_29430	ENOG4108XM1	transcriptional regulator AsnC family
AltI4_29440	ENOG4108RXX	maleylacetoacetate isomerase
AltI4_29460	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AltI4_29470	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AltI4_29490	ENOG4105MIR	Phenylalanine 4-monooxygenase
AltI4_29510	ENOG4105YYT	phage shock protein B
AltI4_29520	ENOG41087YS	Phage shock protein A
AltI4_29530	ENOG4105E51	psp operon transcriptional activator
AltI4_29540	ENOG4105DEF	Extracellular solute-binding protein, family 5
AltI4_29550	ENOG4108I5W	peptide transport system, permease protein
AltI4_29560	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AltI4_29570	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
AltI4_29580	ENOG4108JQ7	(ABC) transporter
AltI4_29590	ENOG4105D9Q	decarboxylase (Beta subunit)
AltI4_29600	ENOG4107QSA	Oxaloacetate decarboxylase
AltI4_29620	ENOG4105VZ8	Transcriptional regulator
AltI4_29650	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AltI4_29660	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AltI4_29670	ENOG4105Y3E	Modulates RecA activity (By similarity)
AltI4_29690	ENOG4105C9K	Endothelin-converting enzyme 1
AltI4_29710	ENOG4105C3R	Methionine synthase
AltI4_29720	ENOG4105C3R	Methionine synthase
AltI4_29730	ENOG4105CVG	Homoserine O-transsuccinylase
AltI4_29760	ENOG4108V3W	Chemotaxis protein, CheW
AltI4_29780	ENOG4107QJE	Chromosome Partitioning Protein
AltI4_29790	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AltI4_29800	ENOG4105CBS	Chea signal transduction histidine kinase
AltI4_29810	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AltI4_29820	ENOG4108VYJ	response regulator receiver protein
AltI4_29830	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AltI4_29850	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AltI4_29860	ENOG4105D7B	Flagellar biosynthesis protein flha
AltI4_29870	ENOG4105D00	flagellar biosynthetic protein flhB
AltI4_29880	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AltI4_29890	ENOG4105VS8	Flagellar biosynthetic protein fliq
AltI4_29900	ENOG4105CN7	Flagellar biosynthetic protein FliP
AltI4_29910	ENOG4105K0P	flagellar biosynthesis protein
AltI4_29920	ENOG4105DD5	Flagellar motor switch protein
AltI4_29930	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AltI4_29970	ENOG4108JIR	Flagellum-specific ATP synthase
AltI4_29990	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AltI4_30000	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AltI4_30010	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AltI4_30020	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_30030	ENOG4105BZU	Histidine kinase
AltI4_30040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_30100	ENOG4106BQ7	Glycosyl Transferase
AltI4_30120	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AltI4_30130	ENOG4107S6X	Glycosyl transferase, family 2
AltI4_30150	ENOG4105K64	Glycosyl transferase, family 2
AltI4_30180	ENOG4105CEY	Amp-dependent synthetase and ligase
AltI4_30190	ENOG4105CHR	reductase
AltI4_30230	ENOG4105D2T	synthase
AltI4_30240	ENOG4105F0R	Cytidylyltransferase
AltI4_30250	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AltI4_30260	ENOG4105C5E	polysaccharide biosynthesis protein
AltI4_30290	ENOG4105MQ3	flagellar protein FliS
AltI4_30310	ENOG41063QE	flagellar protein FlaG
AltI4_30320	ENOG4105I03	Flagellin
AltI4_30330	ENOG4105I03	Flagellin
AltI4_30340	ENOG4105I03	Flagellin
AltI4_30350	ENOG4105I03	Flagellin
AltI4_30380	ENOG4105E1Q	flagellar hook-associated protein
AltI4_30390	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AltI4_30400	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AltI4_30410	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AltI4_30420	ENOG4105CGA	flagellar basal-body rod protein FlgG
AltI4_30430	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AltI4_30440	ENOG4105BZE	flagellar hook protein, FlgE
AltI4_30450	ENOG4105W00	Flagellar hook capping protein
AltI4_30460	ENOG4108ZC9	flagellar basal-body rod protein flgc
AltI4_30470	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AltI4_30480	ENOG4105BZU	Histidine kinase
AltI4_30490	ENOG4107R88	Chemotaxis protein (CheV)
AltI4_30600	ENOG4108ETH	Formylglycinamide ribotide synthetase
AltI4_30610	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AltI4_30630	ENOG4108Z6B	deaminase
AltI4_30660	ENOG4105BZU	Histidine kinase
AltI4_30670	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AltI4_30680	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AltI4_30690	ENOG4105C0B	DNA polymerase III (alpha subunit)
AltI4_30700	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AltI4_30710	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AltI4_30720	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AltI4_30730	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AltI4_30760	ENOG4105DZP	Membrane-associated zinc metalloprotease
AltI4_30770	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AltI4_30780	ENOG4105KNE	Phosphatidate cytidylyltransferase
AltI4_30790	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AltI4_30800	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AltI4_30810	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AltI4_30820	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AltI4_30830	ENOG4105CE9	30S ribosomal protein S2
AltI4_30840	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AltI4_30850	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AltI4_30860	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AltI4_30870	ENOG4105QDK	Flavodoxin
AltI4_30880	ENOG4105DR9	pseudouridine synthase
AltI4_30890	ENOG4105WP7	tRNA pseudouridine synthase C
AltI4_30940	ENOG4105D70	Integrase catalytic subunit
AltI4_30950	ENOG4105F5W	AtP-binding protein
AltI4_31100	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
AltI4_31110	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AltI4_31120	ENOG4105BZU	Histidine kinase
AltI4_31130	ENOG4105EWT	decarboxylase family
AltI4_31160	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AltI4_31170	ENOG4105KQC	Competence protein
AltI4_31180	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AltI4_31190	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AltI4_31200	ENOG4105VIE	preprotein translocase, subunit YajC
AltI4_31210	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AltI4_31220	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AltI4_31250	ENOG4108P9J	Phage shock protein A
AltI4_31300	ENOG4106032	Glutathionylspermidine synthase
AltI4_31330	ENOG4105G6Z	alkaline phosphatase
AltI4_31350	ENOG4107RET	Isocitrate lyase
AltI4_31490	ENOG4105JEU	Glycosyl transferase, family 2
AltI4_31530	ENOG4105CAQ	asparagine synthetase
AltI4_31540	ENOG4108MJN	Glycosyl Transferase
AltI4_31550	ENOG4105DCG	PHP domain protein
AltI4_31620	ENOG4105EXC	Acyl-transferase
AltI4_31630	ENOG4107QRS	glycosyltransferase group 2 family protein
AltI4_31640	ENOG4105EXC	Acyl-transferase
AltI4_31700	ENOG4107T8Q	Glycosyl transferase (Group 1
AltI4_31710	ENOG4105JNK	Glycosyl transferase (Group 1
AltI4_31720	ENOG4105E2K	Glycosyl transferase (Group 1
AltI4_31770	ENOG4105D3Q	Sugar transferase
AltI4_31800	ENOG4108QV3	biosynthesis protein
AltI4_31830	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AltI4_31840	ENOG41082IR	Excinuclease ABC C subunit domain protein
AltI4_31860	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AltI4_31880	ENOG4105D1S	lipid A biosynthesis
AltI4_31920	ENOG4108M1M	outer membrane lipoprotein-sorting protein
AltI4_31930	ENOG4107QPN	acyl-Coa dehydrogenase
AltI4_31940	ENOG4105BZU	Histidine kinase
AltI4_31950	ENOG4107104	thymidine kinase
AltI4_32010	ENOG4105QV4	Tryptophan halogenase
AltI4_32040	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AltI4_32060	ENOG4107QPN	acyl-Coa dehydrogenase
AltI4_32070	ENOG4105BZU	Histidine kinase
AltI4_32080	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AltI4_32090	ENOG4105EJC	lysr family transcriptional regulator
AltI4_32110	ENOG4105CD8	aminopeptidase N
AltI4_32150	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_32170	ENOG4105NAU	thioesterase Superfamily protein
AltI4_32220	ENOG4108ZJ4	polysaccharide deacetylase
AltI4_32230	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AltI4_32240	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AltI4_32250	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AltI4_32290	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AltI4_32300	ENOG4105D0A	hydroxylase
AltI4_32310	ENOG4107RAQ	aminopeptidase
AltI4_32330	ENOG4108RVA	ribokinase
AltI4_32350	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AltI4_32360	ENOG4105E66	phosphoriboisomerase A
AltI4_32370	ENOG4108JQ1	Dehydrogenase
AltI4_32410	ENOG4105XZD	Fe-S protein
AltI4_32440	ENOG4107QN2	dihydrolipoyl dehydrogenase
AltI4_32450	ENOG4107QSN	dihydrolipoamide acetyltransferase
AltI4_32460	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AltI4_32470	ENOG41073TP	transcriptional regulator
AltI4_32500	ENOG4108WIW	Aspartyl protease
AltI4_32510	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AltI4_32520	ENOG4108ZUW	Major pilin subunit
AltI4_32530	ENOG4105D7Q	type ii secretion system
AltI4_32540	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AltI4_32590	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AltI4_32600	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AltI4_32610	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
AltI4_32620	ENOG4107SDU	Methyl-accepting chemotaxis
AltI4_32660	ENOG41067MG	lrgb family
AltI4_32770	ENOG4105C84	Histidine ammonia-lyase
AltI4_32780	ENOG4105CGP	Urocanate hydratase
AltI4_32800	ENOG4105CI2	imidazolone-5-propionate hydrolase
AltI4_32830	ENOG4107S1E	Beta-lactamase
AltI4_32850	ENOG4105HEI	LysR family (Transcriptional regulator
AltI4_32930	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AltI4_32940	ENOG41061N2	exported protein
AltI4_32980	ENOG4105N6Y	Thioredoxin
AltI4_33080	ENOG4105CHR	reductase
AltI4_33090	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_33100	ENOG41064T2	transcriptional regulator, lysR family
AltI4_33110	ENOG4105CKK	Glycosyl transferase, family 2
AltI4_33130	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AltI4_33170	ENOG4105BZU	Histidine kinase
AltI4_33190	ENOG4105CD8	aminopeptidase N
AltI4_33210	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AltI4_33230	ENOG4108UT2	hemolysin iii
AltI4_33240	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_33250	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AltI4_33260	ENOG4105K56	Transcriptional regulator
AltI4_33360	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AltI4_33370	ENOG4105C1J	atp-dependent rna helicase
AltI4_33380	ENOG4105VEQ	Cold shock protein
AltI4_33410	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AltI4_33430	ENOG4108R1E	Serine threonine protein phosphatase 1
AltI4_33440	ENOG4105C30	Nad-dependent epimerase dehydratase
AltI4_33450	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AltI4_33550	ENOG4105ECJ	Glycosyl Transferase
AltI4_33590	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AltI4_33670	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_33720	ENOG4105BZ1	(ABC) transporter
AltI4_33740	ENOG4105EMN	RNA polymerase sigma factor
AltI4_33770	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_33790	ENOG4105CJ3	phosphate transporter
AltI4_33810	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AltI4_33830	ENOG4105C8U	phosphate abc transporter
AltI4_33860	ENOG4105C9X	ppx gppa phosphatase
AltI4_33870	ENOG4105BZU	Histidine kinase
AltI4_33880	ENOG4105WYW	fructose-bisphosphate aldolase
AltI4_33890	ENOG4105BZA	Phosphoglycerate kinase
AltI4_33900	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AltI4_33910	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AltI4_33920	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AltI4_33930	ENOG4105P0I	Adenylate cyclase
AltI4_33970	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
AltI4_33980	ENOG4105BZU	Histidine kinase
AltI4_34000	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_34120	ENOG4108PZW	LysR family Transcriptional regulator
AltI4_34130	ENOG4105CDY	transcriptional regulatory protein
AltI4_34140	ENOG4105D6Z	AFG1 family ATPase
AltI4_34160	ENOG4105C0H	protease
AltI4_34180	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AltI4_34190	ENOG4105VFK	BolA family
AltI4_34210	ENOG4105E3I	toluene tolerance
AltI4_34220	ENOG4107PE3	Mammalian cell entry related domain protein
AltI4_34230	ENOG4105CY3	ABC transporter, permease
AltI4_34240	ENOG4105DHJ	ABC, transporter
AltI4_34260	ENOG4105C2X	Arabinose 5-phosphate isomerase
AltI4_34270	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AltI4_34300	ENOG4108IUZ	ABC transporter
AltI4_34310	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AltI4_34320	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AltI4_34330	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AltI4_34340	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AltI4_34350	ENOG41080Z8	PHOSPHOCARRIER protein
AltI4_34360	ENOG4105BZU	Histidine kinase
AltI4_34370	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AltI4_34390	ENOG4108Z12	YiaAB two helix domain-containing protein
AltI4_34440	ENOG4105CJW	magnesium transporter
AltI4_34450	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AltI4_34480	ENOG4105KB2	stringent starvation protein b
AltI4_34490	ENOG4107MKT	Stringent starvation protein a
AltI4_34500	ENOG4105EIX	cytochrome c1
AltI4_34510	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AltI4_34520	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AltI4_34540	ENOG4108UJD	30S ribosomal protein S9
AltI4_34550	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AltI4_34570	ENOG4105DXN	mazG family
AltI4_34580	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AltI4_34590	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AltI4_34600	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AltI4_34610	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AltI4_34620	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AltI4_34640	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AltI4_34650	ENOG4105T95	Thiol disulfide interChange protein
AltI4_34660	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AltI4_34670	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AltI4_34680	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AltI4_34690	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AltI4_34700	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AltI4_34710	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AltI4_34720	ENOG4105NWN	ApaG protein
AltI4_34740	ENOG4108NVR	Methyl-accepting chemotaxis
AltI4_34800	ENOG4108YZN	class I peptide chain release factor
AltI4_34810	ENOG4105BZU	Histidine kinase
AltI4_34840	ENOG4105CFH	Aspartokinase
AltI4_34860	ENOG4107QIJ	Aconitate hydratase 2
AltI4_34940	ENOG4105EHG	Permease protein
AltI4_34950	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AltI4_34970	ENOG4105EXU	Membrane
AltI4_35010	ENOG410822N	TonB family
AltI4_35020	ENOG4109015	Biopolymer transport protein exbD tolR
AltI4_35100	ENOG4105BZU	Histidine kinase
AltI4_35110	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AltI4_35120	ENOG4105BZU	Histidine kinase
AltI4_35130	ENOG4105DH7	May be involved in recombination (By similarity)
AltI4_35140	ENOG4105DHF	Membrane
AltI4_35150	ENOG4108JCI	Transcriptional regulator
AltI4_35160	ENOG4105DKK	Benzoate
AltI4_35190	ENOG4105K59	histidine triad (HIT) protein
AltI4_35200	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AltI4_35230	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AltI4_35250	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AltI4_35280	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AltI4_35290	ENOG4105VCC	30S ribosomal protein S21
AltI4_35310	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AltI4_35320	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AltI4_35360	ENOG4107RUZ	Sss sodium solute transporter superfamily
AltI4_35370	ENOG4105BZS	acriflavin resistance protein
AltI4_35400	ENOG4105CSU	acyl-Coa dehydrogenase
AltI4_35440	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AltI4_35450	ENOG4105E27	serine threonine protein kinase
AltI4_35470	ENOG4108Z33	Thiol disulfide Interchange Protein
AltI4_35480	ENOG4108M3R	transcriptional activator CadC
AltI4_35520	ENOG4105CHH	sulfate transporter
AltI4_35570	ENOG4105M85	Bola protein
AltI4_35590	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AltI4_35610	ENOG4105BZU	Histidine kinase
AltI4_35620	ENOG4105CHR	reductase
AltI4_35630	ENOG4105E54	alpha-amylase
AltI4_35670	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AltI4_35680	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AltI4_35690	ENOG4107QXK	peptidase
AltI4_35720	ENOG4108UV7	flagellar protein motX
AltI4_35740	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AltI4_35750	ENOG4107QK7	reductase
AltI4_35760	ENOG4107VAM	peptidase, m28
AltI4_35840	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AltI4_35860	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_35870	ENOG4108XM1	transcriptional regulator AsnC family
AltI4_35900	ENOG4105VEQ	Cold shock protein
AltI4_35910	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AltI4_35930	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AltI4_35960	ENOG4105DGW	oligopeptidase A
AltI4_35970	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
AltI4_35980	ENOG4107Z9R	response regulator
AltI4_36000	ENOG4105BZU	Histidine kinase
AltI4_36010	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AltI4_36020	ENOG4105DC8	reductase
AltI4_36040	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AltI4_36050	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AltI4_36130	ENOG4108JJA	ABC, transporter
AltI4_36140	ENOG4105PFC	Transcriptional regulator
AltI4_36180	ENOG41082AG	Plasmid maintenance system antidote protein
AltI4_36200	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AltI4_36210	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AltI4_36220	ENOG41063M6	Cell Division Protein
AltI4_36230	ENOG4105C25	Primosomal protein n'
AltI4_36240	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AltI4_36250	ENOG4105C6K	Malic enzyme
AltI4_36260	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
AltI4_36270	ENOG4105SYT	Methylenetetrahydrofolate reductase
AltI4_36280	ENOG4107S2Z	UPF0761 membrane protein
AltI4_36320	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AltI4_36330	ENOG4105SUU	thioesterase domain
AltI4_36340	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AltI4_36350	ENOG4105D58	Diguanylate phosphodiesterase
AltI4_36360	ENOG4105D58	Diguanylate phosphodiesterase
AltI4_36370	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AltI4_36380	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AltI4_36390	ENOG4105CAK	Cell division ATP-binding protein ftsE
AltI4_36400	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AltI4_36410	ENOG4106H78	methyltransferase
AltI4_36420	ENOG4105R2J	Conserved Protein
AltI4_36430	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AltI4_36450	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AltI4_36460	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AltI4_36470	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AltI4_36480	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AltI4_36490	ENOG4105DJ0	Poly(A) Polymerase
AltI4_36500	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AltI4_36510	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AltI4_36520	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AltI4_36530	ENOG4105BZU	Histidine kinase
AltI4_36540	ENOG4105DY8	decarboxylase
AltI4_36550	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AltI4_36560	ENOG4105E3A	(ABC) transporter
AltI4_36570	ENOG4105DA5	(ABC) transporter
AltI4_36580	ENOG4105BZU	Histidine kinase
AltI4_36590	ENOG4105BZU	Histidine kinase
AltI4_36610	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AltI4_36620	ENOG4105EB3	Histidine kinase
AltI4_36640	ENOG4105D22	carbon starvation protein
AltI4_36650	ENOG4105BZU	Histidine kinase
AltI4_36680	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AltI4_36690	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AltI4_36700	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AltI4_36710	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AltI4_36720	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AltI4_36730	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AltI4_36740	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AltI4_36750	ENOG4108VZM	50s ribosomal protein L10
AltI4_36760	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AltI4_36770	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AltI4_36780	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AltI4_36790	ENOG4105PM1	preprotein translocase subunit SecE
AltI4_36810	ENOG4105CSU	acyl-Coa dehydrogenase
AltI4_36830	ENOG4105BZ1	(ABC) transporter
AltI4_36840	ENOG4105JSC	dimethylmenaquinone methyltransferase
AltI4_36860	ENOG4105M4H	endoribonuclease L-psp
AltI4_36870	ENOG4107TJ9	Cytochrome
AltI4_36910	ENOG4105C1J	atp-dependent rna helicase
AltI4_36920	ENOG4105EKE	dihydroorotase
AltI4_36930	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AltI4_36960	ENOG4105QNF	Outer membrane lipoprotein
AltI4_36970	ENOG4107QM2	Aldo Keto reductase
AltI4_36980	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AltI4_37000	ENOG4105E5W	Transporter
AltI4_37010	ENOG4107QW3	Sucrose phosphorylase
AltI4_37030	ENOG4105EUJ	GTP cyclohydrolase i
AltI4_37040	ENOG410642E	Short chain dehydrogenase
AltI4_37050	ENOG4105DWY	Agmatine deiminase
AltI4_37080	ENOG4107QRT	dEAD DEAH box helicase
AltI4_37120	ENOG4107T0X	DNA ligase
AltI4_37140	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AltI4_37210	ENOG4107IFA	Lipase (EC 3.1.1.3)
AltI4_37230	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AltI4_37240	ENOG4105BZU	Histidine kinase
AltI4_37260	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AltI4_37270	ENOG4105CFC	Transporter
AltI4_37280	ENOG4105EPW	hflc protein
AltI4_37290	ENOG4107QJR	hflk protein
AltI4_37300	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AltI4_37310	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AltI4_37320	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AltI4_37330	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AltI4_37340	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AltI4_37350	ENOG4105K8N	protein family UPF0079, ATPase
AltI4_37360	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AltI4_37370	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AltI4_37380	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AltI4_37410	ENOG4105ETU	transcriptional activator (TenA
AltI4_37420	ENOG4105D06	uba thif-type nad fad binding protein
AltI4_37440	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AltI4_37480	ENOG4105C9B	Cysteine desulfurase
AltI4_37500	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
AltI4_37520	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
AltI4_37530	ENOG4105MYN	Zinc uptake regulation protein
AltI4_37550	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AltI4_37560	ENOG4105CDV	Ompa motb domain protein
AltI4_37570	ENOG4105CDU	Replicative dna helicase
AltI4_37660	ENOG4108RPX	mosc domain containing protein
AltI4_37700	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AltI4_37710	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AltI4_37720	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AltI4_37750	ENOG4108NIW	Leucine export protein LeuE
AltI4_37780	ENOG4105FE9	pseudouridine synthase
AltI4_37820	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AltI4_37920	ENOG4105EAA	nucleoside
AltI4_37950	ENOG4105ETE	Transcriptional regulator (LacI family
AltI4_37980	ENOG4107QM5	aconitate hydratase
AltI4_38050	ENOG4105RD7	BadF BadG BcrA BcrD
AltI4_38060	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AltI4_38070	ENOG4105CE4	GlcNAc 6-P deacetylase
AltI4_38090	ENOG41069D7	Methyl-accepting chemotaxis
AltI4_38100	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_38110	ENOG4108R86	Transcriptional regulator
AltI4_38120	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
AltI4_38130	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AltI4_38150	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AltI4_38160	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
AltI4_38170	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
AltI4_38200	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AltI4_38220	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AltI4_38230	ENOG4105E98	transcriptional regulator DeoR family
AltI4_38240	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AltI4_38250	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AltI4_38280	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
AltI4_38290	ENOG4108HKT	sucrose-6-phosphate hydrolase
AltI4_38360	ENOG4105VZ8	Transcriptional regulator
AltI4_38390	ENOG4105YAJ	CopG Arc MetJ
AltI4_38410	ENOG4105DKT	Transcriptional regulator
AltI4_38420	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
AltI4_38430	ENOG4105DEI	Mannitol dehydrogenase
AltI4_38440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AltI4_38460	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
AltI4_38480	ENOG4105TW1	Carbohydrate-selective porin OprB
AltI4_38500	ENOG4105DEI	Mannitol dehydrogenase
AltI4_38530	ENOG4105DU6	RNA polymerase
AltI4_38580	ENOG4105CHM	Aminotransferase
AltI4_38600	ENOG4105C28	cystathionine
AltI4_38610	ENOG4105DFD	Na H antiporter
AltI4_38630	ENOG4108N3W	hemolysin secretion protein
AltI4_38640	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AltI4_38650	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AltI4_38690	ENOG410804D	Sensor Signal Transduction Histidine Kinase
AltI4_38710	ENOG4105CNM	Receptor
AltI4_38720	ENOG4108ESX	Receptor
AltI4_38740	ENOG4105BZU	Histidine kinase
AltI4_38750	ENOG4105DFF	Rod shape-determining protein mreb
AltI4_38760	ENOG4105EQR	Transposase IS116 IS110 IS902
AltI4_38780	ENOG4108HRK	Histidine kinase
AltI4_38790	ENOG4105CJ1	ABC, transporter
AltI4_38810	ENOG4105EXG	Transcriptional regulator
AltI4_38820	ENOG4105CIS	alcohol dehydrogenase
AltI4_38830	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AltI4_38840	ENOG4105CEN	a g-specific adenine glycosylase
AltI4_38860	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AltI4_38870	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AltI4_38880	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AltI4_38900	ENOG4105BZU	Histidine kinase
AltI4_38910	ENOG41065U4	response regulator
AltI4_38940	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AltI4_38950	ENOG4105N42	UPF0307 protein
AltI4_38960	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AltI4_38980	ENOG4105QD6	exported protein
AltI4_38990	ENOG4105C03	ribonuclease
AltI4_39000	ENOG4108Z03	MAF-like protein
AltI4_39010	ENOG4105VQ7	Rod shape-determining protein MreD
AltI4_39020	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AltI4_39030	ENOG4105DFF	Rod shape-determining protein mreb
AltI4_39090	ENOG4105KHS	type IV fimbrial pilin protein
AltI4_39120	ENOG4105D7Q	type ii secretion system
AltI4_39130	ENOG4107QHF	type ii secretion system protein e
AltI4_39210	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AltI4_39240	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AltI4_39260	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AltI4_39280	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AltI4_39300	ENOG4105EMN	RNA polymerase sigma factor
AltI4_39330	ENOG4105CJW	magnesium transporter
AltI4_39370	ENOG4107XMK	single-stranded DNA-binding protein
AltI4_39440	ENOG4105CNU	cell division protein FtsK
AltI4_39450	ENOG4105BZU	Histidine kinase
AltI4_39530	ENOG4105C3J	Cysteine desulfurase
AltI4_39620	ENOG4105CNT	hydrolase family 2
AltI4_39630	ENOG4105CMR	udp-glucose 4-epimerase
AltI4_39700	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AltI4_39710	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AltI4_39720	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AltI4_39730	ENOG41060NJ	transcriptional regulator
AltI4_39770	ENOG4107EJG	GntR family transcriptional regulator
AltI4_39800	ENOG4105D05	Receptor
AltI4_39820	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AltI4_39830	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
AltI4_39840	ENOG4107QWE	)-transporter
AltI4_39860	ENOG4108J20	pectate lyase
AltI4_39890	ENOG4105E98	transcriptional regulator DeoR family
AltI4_39900	ENOG4106UW1	Major Facilitator superfamily
AltI4_39950	ENOG4105CKI	cobalamin synthesis protein
AltI4_39970	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AltI4_39990	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AltI4_40000	ENOG4105QV4	Tryptophan halogenase
AltI4_40020	ENOG4105QV4	Tryptophan halogenase
AltI4_40040	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AltI4_40110	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AltI4_40160	ENOG4105VV5	Plasmid stabilization system
AltI4_40210	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AltI4_40220	ENOG4105CT4	transporter
AltI4_40240	ENOG4106Z5D	Glycoside Hydrolase Family 43
AltI4_40260	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AltI4_40270	ENOG4106IUH	DTW domain containing protein
AltI4_40280	ENOG4108ESX	Receptor
AltI4_40310	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
AltI4_40320	ENOG4105CGS	Alpha-glucosidase
AltI4_40330	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AltI4_40340	ENOG4107VXZ	Hydrolase
AltI4_40370	ENOG4105EF1	ribulokinase
AltI4_40380	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AltI4_40390	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AltI4_40400	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AltI4_40430	ENOG4107RDB	Major Facilitator
AltI4_40440	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AltI4_40480	ENOG4105BZU	Histidine kinase
AltI4_40490	ENOG4105DSG	hydrolase family 43
AltI4_40530	ENOG4105F0N	pyrophosphate phospho-hydrolase
AltI4_40540	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AltI4_40550	ENOG4105DFU	Cell wall formation (By similarity)
AltI4_40560	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AltI4_40580	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AltI4_40590	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
AltI4_40610	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AltI4_40620	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AltI4_40650	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AltI4_40660	ENOG4105D7W	serine acetyltransferase
AltI4_40670	ENOG4105C4R	Atp-dependent dna helicase
AltI4_40680	ENOG4105BZU	Histidine kinase
AltI4_40700	ENOG4105C3S	Mate efflux family protein
AltI4_40720	ENOG4105FR1	rard protein
AltI4_40730	ENOG4105CJW	magnesium transporter
AltI4_40740	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AltI4_40760	ENOG4105CNG	UPF0061 protein
AltI4_40780	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AltI4_40790	ENOG4108NST	exported protein
AltI4_40820	ENOG4105EGS	Mechanosensitive ion channel
AltI4_40840	ENOG4105C8Q	Methyl-accepting chemotaxis
AltI4_40880	ENOG4105CYC	Transferase
AltI4_40900	ENOG4105BZS	acriflavin resistance protein
AltI4_40910	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AltI4_41030	ENOG4105DS1	cytochrome b561
AltI4_41070	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AltI4_41080	ENOG4105CEP	NADH dehydrogenase
AltI4_41100	ENOG4105C26	Dehydrogenase
AltI4_41120	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AltI4_41150	ENOG4105BZU	Histidine kinase
AltI4_41190	ENOG4105CJ1	ABC, transporter
AltI4_41240	ENOG4105DZG	Dehydrogenase
AltI4_41280	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AltI4_41290	ENOG4107WP9	Histidine kinase
AltI4_41300	ENOG4105ETX	regulatoR
AltI4_41310	ENOG4105BZS	acriflavin resistance protein
AltI4_41330	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AltI4_41410	ENOG4105C09	Bile acid
AltI4_41420	ENOG4108ESX	Receptor
AltI4_41430	ENOG4107E2E	PKHD-type hydroxylase
AltI4_41450	ENOG4105BZU	Histidine kinase
AltI4_41480	ENOG4105BZU	Histidine kinase
AltI4_41490	ENOG4105ETX	regulatoR
AltI4_41530	ENOG4108ZNX	Heat shock protein
AltI4_41560	ENOG4105CC0	LysR family Transcriptional regulator
AltI4_41580	ENOG4105C4W	S-formylglutathione hydrolase
AltI4_41610	ENOG4108RYR	transcriptional regulator AsnC family
AltI4_41620	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AltI4_41700	ENOG4105CH2	amidohydrolase
AltI4_41720	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AltI4_41770	ENOG4108JQ6	ABC transporter
AltI4_41780	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AltI4_41810	ENOG4105CJP	fad dependent oxidoreductase
AltI4_41830	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AltI4_41850	ENOG4105C26	Dehydrogenase
AltI4_41920	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AltI4_41930	ENOG410804X	Transcriptional regulator
AltI4_41950	ENOG4105D9R	oxidoreductase
AltI4_41960	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AltI4_41970	ENOG4105BZU	Histidine kinase
AltI4_41980	ENOG4108Q5Y	Membrane
AltI4_41990	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AltI4_42000	ENOG4105D03	DNA-3-methyladenine glycosylase II
AltI4_42010	ENOG41066YJ	Beta-lactamase
AltI4_42020	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AltI4_42080	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AltI4_42090	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AltI4_42100	ENOG4105W8H	transhydrogenase (subunit alpha
AltI4_42110	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AltI4_42130	ENOG4105EKQ	RNA-directed DNA polymerase
AltI4_42140	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AltI4_42150	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AltI4_42160	ENOG4105NBR	Pectinesterase
AltI4_42190	ENOG4105E4I	Glycoside hydrolase family 28
AltI4_42200	ENOG4105F5H	Glycosyl Hydrolase Family 88
AltI4_42210	ENOG4105D05	Receptor
AltI4_42220	ENOG4107TDE	lipolytic protein G-D-S-L family
AltI4_42230	ENOG4105BZU	Histidine kinase
AltI4_42240	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AltI4_42250	ENOG4108UHU	Aldolase
AltI4_42260	ENOG4105DEI	Mannitol dehydrogenase
AltI4_42270	ENOG4105D2H	Uronic isomerase
AltI4_42280	ENOG4105CTX	dehydratase
AltI4_42290	ENOG4105ETE	Transcriptional regulator (LacI family
AltI4_42300	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AltI4_42320	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AltI4_42330	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
AltI4_42340	ENOG4105CHR	reductase
AltI4_42370	ENOG4105VF7	tolerance protein
AltI4_42380	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AltI4_42400	ENOG4108N3W	hemolysin secretion protein
AltI4_42430	ENOG4108VYJ	response regulator receiver protein
AltI4_42440	ENOG4105CBS	Chea signal transduction histidine kinase
AltI4_42450	ENOG4108V3W	Chemotaxis protein, CheW
AltI4_42460	ENOG4107SDU	Methyl-accepting chemotaxis
AltI4_42470	ENOG4105BZU	Histidine kinase
AltI4_42480	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AltI4_42490	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AltI4_42500	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AltI4_42510	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AltI4_42520	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AltI4_42600	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AltI4_42610	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AltI4_42620	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AltI4_42630	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AltI4_42640	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AltI4_42660	ENOG4105C12	Phosphoribosylglycinamide synthetase
AltI4_42690	ENOG4105EYW	Ion transport protein
AltI4_42700	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AltI4_42710	ENOG4105DN9	Na H antiporter
AltI4_42720	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AltI4_42730	ENOG4105E0F	Histidine kinase
AltI4_42750	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AltI4_42760	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AltI4_42770	ENOG4105VEJ	Heat shock protein
AltI4_42780	ENOG4108XKW	General secretion pathway protein C
AltI4_42800	ENOG4107QHF	type ii secretion system protein e
AltI4_42810	ENOG4105D7Q	type ii secretion system
AltI4_42820	ENOG4108VAU	general secretion pathway protein G
AltI4_42910	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AltI4_42920	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
AltI4_42930	ENOG4107RK2	ADP-ribose diphosphatase NudE
AltI4_42950	ENOG4108YYC	ycei family
AltI4_42960	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AltI4_42970	ENOG4105DJ9	glucan biosynthesis protein
AltI4_43000	ENOG4105DNZ	Alpha Beta Hydrolase
AltI4_43020	ENOG4105C5H	ABC transporter
AltI4_43040	ENOG4105P66	Membrane
AltI4_43060	ENOG4107S78	Band 7 protein
AltI4_43070	ENOG4105VEQ	Cold shock protein
AltI4_43120	ENOG41069P5	Protein slyX homolog
AltI4_43140	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AltI4_43160	ENOG4108RRZ	Transcription elongation factor GreB
AltI4_43170	ENOG4106B0W	Curli production assembly transport component CsgG
AltI4_43190	ENOG4107Y60	(LipO)protein
AltI4_43200	ENOG4105BZM	domain protein
AltI4_43230	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AltI4_43240	ENOG4105MJ2	Competence protein
AltI4_43260	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AltI4_43270	ENOG4107R73	Mate efflux family protein
AltI4_43280	ENOG4107BJW	polysaccharide deacetylase
AltI4_43310	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AltI4_43320	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
AltI4_43370	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
AltI4_43380	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AltI4_43390	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AltI4_43400	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AltI4_43420	ENOG4105FQ6	thiopurine methyltransferase
AltI4_43450	ENOG4105BZU	Histidine kinase
AltI4_43500	ENOG4105E55	glycerol-3-phosphate acyltransferase
AltI4_43520	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AltI4_43530	ENOG4105J4Q	Transcriptional regulator
AltI4_43550	ENOG4105CHR	reductase
AltI4_43570	ENOG4105CT4	transporter
AltI4_43580	ENOG4105F5H	Glycosyl Hydrolase Family 88
AltI4_43590	ENOG4105EKC	
AltI4_43620	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
AltI4_43700	ENOG4105C7B	Threonine dehydratase
AltI4_43710	ENOG4105C01	Dihydroxy-acid dehydratase
AltI4_43720	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AltI4_43730	ENOG4105C0P	Mg chelatase subunit ChlI
AltI4_43740	ENOG4105EMY	transcriptional regulator
AltI4_43750	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AltI4_43770	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AltI4_43790	ENOG4105C2C	drug resistance transporter, Bcr CflA
AltI4_43800	ENOG4105DSG	hydrolase family 43
AltI4_43830	ENOG4105CSR	polyphosphate kinase 2
AltI4_43870	ENOG4105MA0	exported protein
AltI4_43910	ENOG4105C5I	Dehydrogenase
AltI4_43930	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AltI4_43940	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AltI4_44040	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AltI4_44070	ENOG4105CI2	imidazolone-5-propionate hydrolase
AltI4_44110	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AltI4_44120	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AltI4_44130	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AltI4_44140	ENOG4105DSJ	YicC domain protein
AltI4_44160	ENOG4105CAF	HipA N-terminal domain protein
AltI4_44180	ENOG4107YB6	acetyltransferase, (GNAT) family
AltI4_44190	ENOG4105QV4	Tryptophan halogenase
AltI4_44230	ENOG4105CT4	transporter
AltI4_44240	ENOG41060NJ	transcriptional regulator
AltI4_44270	ENOG4108N3W	hemolysin secretion protein
AltI4_44290	ENOG4105CDV	Ompa motb domain protein
AltI4_44300	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AltI4_44370	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AltI4_44380	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AltI4_44390	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AltI4_44400	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AltI4_44410	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AltI4_44420	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AltI4_44440	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AltI4_44460	ENOG4105FA0	parb-like partition protein
AltI4_44470	ENOG4107QJE	Chromosome Partitioning Protein
AltI4_44480	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AltI4_44490	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AltI4_44520	ENOG4105QTB	Flavodoxin
AltI4_44540	ENOG4108VPT	UPF0234 protein
AltI4_44550	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AltI4_44560	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AltI4_44570	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AltI4_44720	ENOG4105D05	Receptor
AltI4_44730	ENOG4105R0I	Feruloyl esterase
AltI4_44750	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_44760	ENOG410846T	CoA-transferase family III
AltI4_44770	ENOG4105E39	Enoyl-CoA hydratase
AltI4_44780	ENOG4105EA8	2-Nitropropane dioxygenase
AltI4_44790	ENOG4105CHU	acetyl-coa acetyltransferase
AltI4_44810	ENOG4108UKI	Enoyl-CoA hydratase
AltI4_44840	ENOG4105DNH	Major Facilitator
AltI4_44860	ENOG4105CHU	acetyl-coa acetyltransferase
AltI4_44870	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AltI4_44920	ENOG4105CT4	transporter
AltI4_44950	ENOG4105EBR	Carboxylesterase
AltI4_44960	ENOG4107EJG	GntR family transcriptional regulator
AltI4_44990	ENOG4105C1G	acyl-Coa dehydrogenase
AltI4_45010	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AltI4_45020	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AltI4_45040	ENOG4105DSG	hydrolase family 43
AltI4_45060	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
AltI4_45090	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
AltI4_45120	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AltI4_45140	ENOG4105D05	Receptor
AltI4_45230	ENOG4105E2D	ec 3.2.1.52
AltI4_45240	ENOG4105RD7	BadF BadG BcrA BcrD
AltI4_45250	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AltI4_45260	ENOG4105CE4	GlcNAc 6-P deacetylase
AltI4_45300	ENOG4105ERH	Fumarylacetoacetate hydrolase
AltI4_45310	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AltI4_45330	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AltI4_45350	ENOG4105C01	Dihydroxy-acid dehydratase
AltI4_45370	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase