locus-tag	class	description
AltI4_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AltI4_00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AltI4_00040	COG0187	DNA topoisomerase II activity
AltI4_00090	COG2818	Glycosylase
AltI4_00110	COG3078	GTPase activator activity
AltI4_00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AltI4_00150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AltI4_00160	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AltI4_00170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AltI4_00190	COG0741	lytic transglycosylase activity
AltI4_00240	COG0569	domain protein
AltI4_00250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AltI4_00250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AltI4_00260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AltI4_00280	COG1652	LysM domain
AltI4_00290	COG0758	DNA mediated transformation
AltI4_00330	COG0009	L-threonylcarbamoyladenylate synthase
AltI4_00340	COG0408	coproporphyrinogen oxidase activity
AltI4_00350	COG3047	cAMP biosynthetic process
AltI4_00380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AltI4_00410	COG0587	DNA-directed DNA polymerase activity
AltI4_00480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AltI4_00530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AltI4_00540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AltI4_00590	COG3642	lipopolysaccharide core region biosynthetic process
AltI4_00600	COG0859	PFAM glycosyl transferase family 9
AltI4_00640	COG0156	8-amino-7-oxononanoate synthase activity
AltI4_00660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AltI4_00670	COG0705	Rhomboid family
AltI4_00690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AltI4_00700	COG2960	long-chain fatty acid transporting porin activity
AltI4_00710	COG0210	DNA helicase
AltI4_00850	COG0582	viral genome integration into host DNA
AltI4_00870	COG0556	nucleotide-excision repair
AltI4_00980	COG4771	TonB-dependent receptor
AltI4_01010	COG1012	belongs to the aldehyde dehydrogenase family
AltI4_01020	COG1024	Enoyl-CoA hydratase
AltI4_01150	COG2175	clavaminate synthase activity
AltI4_01170	COG3384	dioxygenase
AltI4_01200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AltI4_01210	COG1335	isochorismatase
AltI4_01280	COG4638	Rieske (2fe-2S)
AltI4_01300	COG2207	Transcriptional regulator
AltI4_01360	COG3250	beta-galactosidase activity
AltI4_01410	COG0494	nUDIX hydrolase
AltI4_01420	COG1609	Transcriptional regulator
AltI4_01430	COG4771	TonB-dependent receptor
AltI4_01520	COG0179	Fumarylacetoacetate (FAA) hydrolase
AltI4_01550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AltI4_01570	COG0583	DNA-binding transcription factor activity
AltI4_01610	COG0642	Histidine kinase
AltI4_01620	COG0745	RESPONSE REGULATOR receiver
AltI4_01700	COG3106	COG3106 Predicted ATPase
AltI4_01770	COG1178	ABC-type Fe3 transport system permease component
AltI4_01780	COG3842	ATPase activity
AltI4_01820	COG2959	enzyme of heme biosynthesis
AltI4_01840	COG0181	hydroxymethylbilane synthase activity
AltI4_01850	COG0400	carboxylic ester hydrolase activity
AltI4_01860	COG0194	GDP metabolic process
AltI4_01880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AltI4_01900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AltI4_01940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AltI4_01960	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AltI4_01960	COG0678	peroxiredoxin activity
AltI4_01980	COG2081	HI0933 family
AltI4_02010	COG0667	Aldo Keto reductase
AltI4_02020	COG0577	efflux transmembrane transporter activity
AltI4_02040	COG1136	(ABC) transporter
AltI4_02060	COG1312	Catalyzes the dehydration of D-mannonate
AltI4_02070	COG2186	Transcriptional regulator
AltI4_02110	COG0583	DNA-binding transcription factor activity
AltI4_02120	COG0697	spore germination
AltI4_02150	COG0484	heat shock protein binding
AltI4_02170	COG0612	Peptidase, M16
AltI4_02180	COG0535	radical SAM domain protein
AltI4_02220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AltI4_02320	COG0583	DNA-binding transcription factor activity
AltI4_02330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AltI4_02350	COG2851	Citrate transporter
AltI4_02370	COG4771	TonB-dependent receptor
AltI4_02420	COG3300	MHYT domain
AltI4_02420	COG5001	Diguanylate cyclase
AltI4_02440	COG0446	pyridine nucleotide-disulphide oxidoreductase
AltI4_02470	COG1294	oxidase, subunit
AltI4_02480	COG4988	ABC transporter
AltI4_02490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AltI4_02570	COG0730	response to heat
AltI4_02610	COG2723	6-phospho-beta-galactosidase activity
AltI4_02620	COG2211	Major facilitator Superfamily
AltI4_02650	COG0840	transmembrane signaling receptor activity
AltI4_02670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AltI4_02700	COG4115	mRNA cleavage
AltI4_02730	COG5002	protein histidine kinase activity
AltI4_02760	COG0347	Belongs to the P(II) protein family
AltI4_02780	COG2199	diguanylate cyclase activity
AltI4_02780	COG2203	Gaf domain
AltI4_02800	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AltI4_02870	COG0089	rRNA binding
AltI4_02890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AltI4_02910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AltI4_02940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AltI4_02950	COG1064	alcohol dehydrogenase
AltI4_02960	COG1519	Transferase
AltI4_02970	COG0025	NhaP-type Na H and K H
AltI4_03020	COG0121	glutamine amidotransferase
AltI4_03040	COG0339	signal peptide processing
AltI4_03050	COG0788	formyltetrahydrofolate deformylase activity
AltI4_03060	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AltI4_03070	COG1643	Atp-dependent helicase
AltI4_03090	COG2951	lytic endotransglycosylase activity
AltI4_03140	COG3243	poly(R)-hydroxyalkanoic acid synthase
AltI4_03160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AltI4_03180	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AltI4_03190	COG2354	Protein conserved in bacteria
AltI4_03220	COG0004	ammonium transporteR
AltI4_03230	COG0405	Gamma-glutamyltransferase
AltI4_03240	COG2837	iron assimilation
AltI4_03250	COG0583	DNA-binding transcription factor activity
AltI4_03260	COG0501	Belongs to the peptidase M48B family
AltI4_03310	COG0540	Belongs to the ATCase OTCase family
AltI4_03330	COG4999	Histidine kinase
AltI4_03330	COG2205	protein histidine kinase activity
AltI4_03330	COG3437	response regulator, receiver
AltI4_03330	COG3850	Histidine kinase
AltI4_03380	COG1012	belongs to the aldehyde dehydrogenase family
AltI4_03400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AltI4_03440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AltI4_03480	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AltI4_03500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AltI4_03570	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AltI4_03580	COG0281	malic enzyme
AltI4_03660	COG2200	EAL domain
AltI4_03690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AltI4_03690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AltI4_03710	COG0137	argininosuccinate synthase activity
AltI4_03750	COG1803	Methylglyoxal synthase
AltI4_03780	COG0745	RESPONSE REGULATOR receiver
AltI4_03790	COG2205	protein histidine kinase activity
AltI4_03800	COG2267	carboxylic ester hydrolase activity
AltI4_03810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AltI4_03820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AltI4_03840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AltI4_03850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AltI4_03860	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AltI4_03870	COG4942	peptidase
AltI4_03880	COG2861	carbohydrate metabolic process
AltI4_03890	COG4206	TonB-dependent receptor
AltI4_03900	COG0457	Tetratricopeptide repeat
AltI4_03920	COG0584	glycerophosphoryl diester phosphodiesterase
AltI4_03950	COG1162	GTPase activity
AltI4_03960	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AltI4_03990	COG0028	Belongs to the TPP enzyme family
AltI4_04040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AltI4_04050	COG0805	protein transport
AltI4_04070	COG0084	hydrolase, TatD family'
AltI4_04080	COG3706	GGDEF domain
AltI4_04100	COG0248	Ppx GppA phosphatase
AltI4_04110	COG0513	Belongs to the DEAD box helicase family
AltI4_04120	COG3118	belongs to the thioredoxin family
AltI4_04140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AltI4_04160	COG0784	Response regulator, receiver
AltI4_04160	COG2205	protein histidine kinase activity
AltI4_04190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AltI4_04210	COG0783	Belongs to the Dps family
AltI4_04220	COG2133	pyrroloquinoline quinone binding
AltI4_04230	COG1506	peptidase
AltI4_04230	COG4946	Tricorn protease homolog
AltI4_04230	COG0823	Involved in the tonB-independent uptake of proteins
AltI4_04250	COG3118	belongs to the thioredoxin family
AltI4_04270	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AltI4_04290	COG1012	belongs to the aldehyde dehydrogenase family
AltI4_04340	COG2378	regulation of single-species biofilm formation
AltI4_04360	COG1757	Na H antiporter
AltI4_04370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AltI4_04460	COG3876	Protein conserved in bacteria
AltI4_04480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AltI4_04510	COG2971	BadF BadG BcrA BcrD
AltI4_04530	COG4251	negative regulation of phosphorylation
AltI4_04530	COG3706	GGDEF domain
AltI4_04530	COG2203	Gaf domain
AltI4_04530	COG5001	Diguanylate cyclase
AltI4_04690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AltI4_04710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AltI4_04750	COG2197	response regulator
AltI4_04770	COG0515	serine threonine protein kinase
AltI4_04820	COG2045	Belongs to the ComB family
AltI4_04840	COG0667	Aldo Keto reductase
AltI4_04850	COG1283	sodium-dependent phosphate transmembrane transporter activity
AltI4_04890	COG1247	-acetyltransferase
AltI4_04920	COG0189	ligase activity
AltI4_04920	COG4067	protein conserved in archaea
AltI4_04940	COG0189	ligase activity
AltI4_04950	COG2205	protein histidine kinase activity
AltI4_04950	COG0784	Response regulator, receiver
AltI4_04970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AltI4_04980	COG0517	IMP dehydrogenase activity
AltI4_04980	COG0516	GMP reductase activity
AltI4_05020	COG0840	transmembrane signaling receptor activity
AltI4_05080	COG2234	aminopeptidase activity
AltI4_05100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AltI4_05110	COG0572	uridine kinase
AltI4_05150	COG1438	arginine binding
AltI4_05160	COG0039	L-malate dehydrogenase activity
AltI4_05170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AltI4_05180	COG0545	Peptidyl-prolyl cis-trans isomerase
AltI4_05200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AltI4_05210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AltI4_05220	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AltI4_05230	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AltI4_05240	COG1805	sodium ion transport
AltI4_05250	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AltI4_05260	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AltI4_05270	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AltI4_05280	COG2871	sodium ion transport
AltI4_05290	COG1477	protein flavinylation
AltI4_05310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AltI4_05340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AltI4_05370	COG3123	guanosine phosphorylase activity
AltI4_05380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AltI4_05400	COG5002	protein histidine kinase activity
AltI4_05400	COG5001	Diguanylate cyclase
AltI4_05440	COG0702	epimerase
AltI4_05460	COG0848	biopolymer transport protein
AltI4_05480	COG0716	FMN binding
AltI4_05510	COG0384	phenazine biosynthesis protein PhzF
AltI4_05520	COG1522	sequence-specific DNA binding
AltI4_05530	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AltI4_05540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AltI4_05570	COG0733	neurotransmitter:sodium symporter activity
AltI4_05580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AltI4_05620	COG0668	transmembrane transport
AltI4_05630	COG0204	Acyl-transferase
AltI4_05640	COG0204	Acyl-transferase
AltI4_05650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AltI4_05660	COG0667	Aldo Keto reductase
AltI4_05670	COG1472	Belongs to the glycosyl hydrolase 3 family
AltI4_05770	COG3291	Pkd domain containing protein
AltI4_05790	COG2115	Belongs to the xylose isomerase family
AltI4_05800	COG1070	Carbohydrate kinase
AltI4_05810	COG2207	Transcriptional regulator
AltI4_05810	COG1609	Transcriptional regulator
AltI4_05840	COG0583	DNA-binding transcription factor activity
AltI4_05870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AltI4_05880	COG2207	Transcriptional regulator
AltI4_05880	COG1917	Cupin 2, conserved barrel domain protein
AltI4_05890	COG3250	beta-galactosidase activity
AltI4_05900	COG0673	inositol 2-dehydrogenase activity
AltI4_05910	COG0477	Major facilitator Superfamily
AltI4_05990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AltI4_06020	COG1842	Phage shock protein A
AltI4_06070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AltI4_06110	COG3300	MHYT domain
AltI4_06110	COG5001	Diguanylate cyclase
AltI4_06130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AltI4_06140	COG2205	protein histidine kinase activity
AltI4_06150	COG5001	Diguanylate cyclase
AltI4_06170	COG1309	transcriptional regulator
AltI4_06240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AltI4_06260	COG0183	Belongs to the thiolase family
AltI4_06270	COG1250	3-hydroxyacyl-CoA dehydrogenase
AltI4_06270	COG1024	Enoyl-CoA hydratase
AltI4_06290	COG0006	proline dipeptidase activity
AltI4_06310	COG0142	geranyltranstransferase activity
AltI4_06430	COG3385	transposase activity
AltI4_06440	COG4191	Histidine kinase
AltI4_06440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_06450	COG0784	Response regulator, receiver
AltI4_06450	COG3437	response regulator, receiver
AltI4_06460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_06460	COG4191	Histidine kinase
AltI4_06480	COG4942	peptidase
AltI4_06480	COG1388	LysM domain
AltI4_06490	COG1238	metal cluster binding
AltI4_06510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AltI4_06520	COG0585	pseudouridine synthase activity
AltI4_06550	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AltI4_06580	COG2119	membrane
AltI4_06590	COG4991	sh3 domain protein
AltI4_06620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AltI4_06640	COG0494	nUDIX hydrolase
AltI4_06660	COG0730	response to heat
AltI4_06670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AltI4_06680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AltI4_06690	COG2201	protein-glutamate methylesterase activity
AltI4_06700	COG3706	GGDEF domain
AltI4_06740	COG0564	pseudouridine synthase activity
AltI4_06750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AltI4_06760	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AltI4_06780	COG1648	precorrin-2 dehydrogenase activity
AltI4_06780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AltI4_06790	COG0513	Belongs to the DEAD box helicase family
AltI4_06840	COG1538	Outer membrane efflux protein
AltI4_06850	COG0494	nUDIX hydrolase
AltI4_06860	COG3151	Protein conserved in bacteria
AltI4_06870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AltI4_06880	COG3150	esterase
AltI4_06890	COG0187	DNA topoisomerase II activity
AltI4_06940	COG1509	lysine 2,3-aminomutase activity
AltI4_07050	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AltI4_07080	COG0200	Binds to the 23S rRNA
AltI4_07090	COG0201	protein transport
AltI4_07130	COG0202	RNA polymerase activity
AltI4_07230	COG1484	DNA-dependent DNA replication
AltI4_07250	COG4584	PFAM Integrase catalytic
AltI4_07270	COG2963	transposase activity
AltI4_07430	COG1216	Glycosyl transferase, family 2
AltI4_07440	COG0463	Glycosyl transferase, family 2
AltI4_07460	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AltI4_07500	COG2197	response regulator
AltI4_07510	COG2197	response regulator
AltI4_07550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AltI4_07610	COG1091	dTDP-4-dehydrorhamnose reductase activity
AltI4_07640	COG1088	dTDP-glucose 4,6-dehydratase activity
AltI4_07660	COG0438	transferase activity, transferring glycosyl groups
AltI4_07660	COG1216	Glycosyl transferase, family 2
AltI4_07680	COG0417	DNA replication proofreading
AltI4_07700	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_07760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_07760	COG4191	Histidine kinase
AltI4_07780	COG2205	protein histidine kinase activity
AltI4_07780	COG2198	Histidine kinase
AltI4_07780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_07780	COG0784	Response regulator, receiver
AltI4_07820	COG0745	RESPONSE REGULATOR receiver
AltI4_07820	COG3706	GGDEF domain
AltI4_07850	COG0730	response to heat
AltI4_07870	COG0583	DNA-binding transcription factor activity
AltI4_07890	COG0531	amino acid
AltI4_07920	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AltI4_08010	COG0583	DNA-binding transcription factor activity
AltI4_08020	COG1696	Membrane protein involved in D-alanine export
AltI4_08040	COG2207	Transcriptional regulator
AltI4_08050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AltI4_08070	COG1538	Outer membrane efflux protein
AltI4_08100	COG4771	TonB-dependent receptor
AltI4_08110	COG0583	DNA-binding transcription factor activity
AltI4_08120	COG1012	belongs to the aldehyde dehydrogenase family
AltI4_08140	COG2010	Cytochrome c
AltI4_08140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AltI4_08160	COG1131	(ABC) transporter
AltI4_08180	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AltI4_08190	COG4585	Histidine kinase
AltI4_08200	COG2197	response regulator
AltI4_08210	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AltI4_08210	COG3264	Mechanosensitive ion channel
AltI4_08220	COG1595	DNA-templated transcription, initiation
AltI4_08280	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_08320	COG1854	S-ribosylhomocysteine lyase activity
AltI4_08340	COG2197	response regulator
AltI4_08350	COG4585	Histidine kinase
AltI4_08380	COG0625	glutathione transferase activity
AltI4_08390	COG1234	tRNA 3'-trailer cleavage
AltI4_08540	COG1595	DNA-templated transcription, initiation
AltI4_08600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AltI4_08620	COG0625	glutathione transferase activity
AltI4_08650	COG1733	regulation of RNA biosynthetic process
AltI4_08670	COG2249	NAD(P)H dehydrogenase (quinone) activity
AltI4_08770	COG0795	lipopolysaccharide-transporting ATPase activity
AltI4_08780	COG0795	lipopolysaccharide-transporting ATPase activity
AltI4_08790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AltI4_08800	COG2927	DNA polymerase III (CHI subunit)
AltI4_08810	COG0525	valine-tRNA ligase activity
AltI4_08820	COG2223	nitrite transmembrane transporter activity
AltI4_08830	COG0515	serine threonine protein kinase
AltI4_08830	COG2815	serine threonine protein kinase
AltI4_08850	COG4771	TonB-dependent receptor
AltI4_08860	COG1858	cytochrome C peroxidase
AltI4_08890	COG4206	TonB-dependent receptor
AltI4_08910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AltI4_08920	COG3706	GGDEF domain
AltI4_08940	COG0514	ATP-dependent DNA helicase (RecQ)
AltI4_08960	COG2832	Protein of unknown function (DUF454)
AltI4_08970	COG1294	oxidase, subunit
AltI4_08980	COG1271	oxidase subunit
AltI4_09200	COG0501	Belongs to the peptidase M48B family
AltI4_09210	COG4269	membrane
AltI4_09230	COG0204	Acyl-transferase
AltI4_09240	COG3437	response regulator, receiver
AltI4_09250	COG2204	response regulator
AltI4_09260	COG3852	Histidine kinase
AltI4_09280	COG0174	glutamine synthetase
AltI4_09310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AltI4_09320	COG1914	H( )-stimulated, divalent metal cation uptake system
AltI4_09450	COG1523	belongs to the glycosyl hydrolase 13 family
AltI4_09500	COG1902	pentaerythritol trinitrate reductase activity
AltI4_09520	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AltI4_09530	COG0739	heme binding
AltI4_09540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AltI4_09580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AltI4_09660	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_09690	COG4221	oxidoreductase activity
AltI4_09710	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_09730	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_09780	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AltI4_09830	COG1162	GTPase activity
AltI4_09850	COG0653	protein targeting
AltI4_09870	COG0183	Belongs to the thiolase family
AltI4_09880	COG1250	3-hydroxyacyl-CoA dehydrogenase
AltI4_09930	COG1960	acyl-CoA dehydrogenase activity
AltI4_09940	COG1960	acyl-CoA dehydrogenase activity
AltI4_09980	COG0183	Belongs to the thiolase family
AltI4_10000	COG4771	TonB-dependent receptor
AltI4_10020	COG0493	'glutamate synthase
AltI4_10030	COG0070	glutamate synthase
AltI4_10030	COG0069	glutamate synthase activity
AltI4_10030	COG0067	glutamate synthase
AltI4_10040	COG0784	Response regulator, receiver
AltI4_10040	COG5002	protein histidine kinase activity
AltI4_10040	COG2198	Histidine kinase
AltI4_10080	COG2828	Protein conserved in bacteria
AltI4_10090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AltI4_10100	COG0372	Belongs to the citrate synthase family
AltI4_10110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AltI4_10140	COG2823	Periplasmic or secreted lipoprotein
AltI4_10160	COG0792	nuclease activity
AltI4_10180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AltI4_10210	COG1748	Saccharopine dehydrogenase
AltI4_10270	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AltI4_10300	COG5001	Diguanylate cyclase
AltI4_10300	COG3300	MHYT domain
AltI4_10310	COG2205	protein histidine kinase activity
AltI4_10310	COG0784	Response regulator, receiver
AltI4_10350	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AltI4_10360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AltI4_10410	COG1506	peptidase
AltI4_10410	COG0823	Involved in the tonB-independent uptake of proteins
AltI4_10450	COG0762	integral membrane protein
AltI4_10460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AltI4_10510	COG0596	Alpha beta hydrolase
AltI4_10540	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AltI4_10560	COG0189	ligase activity
AltI4_10570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AltI4_10590	COG0668	transmembrane transport
AltI4_10620	COG0840	transmembrane signaling receptor activity
AltI4_10630	COG0745	RESPONSE REGULATOR receiver
AltI4_10650	COG0835	chemotaxis
AltI4_10680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AltI4_10700	COG4191	Histidine kinase
AltI4_10710	COG2204	response regulator
AltI4_10720	COG3706	GGDEF domain
AltI4_10750	COG0678	peroxiredoxin activity
AltI4_10750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AltI4_10790	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AltI4_10800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AltI4_10870	COG1119	ATPase activity
AltI4_10880	COG2001	Belongs to the MraZ family
AltI4_10900	COG3116	cell division
AltI4_10910	COG0768	penicillin binding
AltI4_10920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AltI4_10930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AltI4_10950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AltI4_10960	COG0772	Belongs to the SEDS family
AltI4_10970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AltI4_10980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AltI4_10990	COG1181	Belongs to the D-alanine--D-alanine ligase family
AltI4_11000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AltI4_11010	COG0849	cell division
AltI4_11030	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AltI4_11040	COG1196	nuclear chromosome segregation
AltI4_11040	COG0741	lytic transglycosylase activity
AltI4_11040	COG0739	heme binding
AltI4_11060	COG0494	nUDIX hydrolase
AltI4_11080	COG0840	transmembrane signaling receptor activity
AltI4_11080	COG3290	protein histidine kinase activity
AltI4_11090	COG0835	chemotaxis
AltI4_11100	COG2201	protein-glutamate methylesterase activity
AltI4_11120	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AltI4_11130	COG0745	RESPONSE REGULATOR receiver
AltI4_11140	COG0643	Histidine kinase
AltI4_11140	COG2198	Histidine kinase
AltI4_11160	COG1192	Involved in chromosome partitioning
AltI4_11180	COG0840	transmembrane signaling receptor activity
AltI4_11190	COG0840	transmembrane signaling receptor activity
AltI4_11200	COG2186	Transcriptional regulator
AltI4_11210	COG2186	Transcriptional regulator
AltI4_11290	COG0800	Aldolase
AltI4_11300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AltI4_11310	COG2271	Major facilitator Superfamily
AltI4_11350	COG2084	Dehydrogenase
AltI4_11430	COG0583	DNA-binding transcription factor activity
AltI4_11450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AltI4_11460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AltI4_11470	COG0513	Belongs to the DEAD box helicase family
AltI4_11480	COG0617	tRNA 3'-terminal CCA addition
AltI4_11490	COG3267	Type II secretory pathway component ExeA
AltI4_11490	COG3409	Peptidoglycan-binding domain 1 protein
AltI4_11520	COG0066	3-isopropylmalate dehydratase activity
AltI4_11540	COG0473	3-isopropylmalate dehydrogenase activity
AltI4_11550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AltI4_11590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AltI4_11650	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AltI4_11660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AltI4_11670	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AltI4_11690	COG1138	Cytochrome C-type biogenesis protein
AltI4_11740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AltI4_11760	COG3104	oligopeptide transport
AltI4_11810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AltI4_11820	COG1215	transferase activity, transferring glycosyl groups
AltI4_11850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AltI4_11860	COG0483	inositol monophosphate 1-phosphatase activity
AltI4_11870	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AltI4_11880	COG1045	serine acetyltransferase
AltI4_11890	COG1959	2 iron, 2 sulfur cluster binding
AltI4_11900	COG1104	cysteine desulfurase activity
AltI4_11910	COG0719	Fe-S assembly protein
AltI4_11920	COG0396	ATPase activity
AltI4_11930	COG0719	Fe-S assembly protein
AltI4_11940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AltI4_11970	COG2166	iron-sulfur cluster assembly
AltI4_11990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AltI4_12010	COG1426	Protein conserved in bacteria
AltI4_12040	COG2976	Protein conserved in bacteria
AltI4_12050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AltI4_12080	COG1570	exodeoxyribonuclease VII activity
AltI4_12090	COG0516	GMP reductase activity
AltI4_12090	COG0517	IMP dehydrogenase activity
AltI4_12120	COG0840	transmembrane signaling receptor activity
AltI4_12130	COG0123	including yeast histone deacetylase and acetoin utilization protein
AltI4_12150	COG1234	tRNA 3'-trailer cleavage
AltI4_12170	COG1720	tRNA m6t6A37 methyltransferase activity
AltI4_12180	COG1131	(ABC) transporter
AltI4_12240	COG0544	peptidyl-prolyl cis-trans isomerase activity
AltI4_12250	COG0740	serine-type endopeptidase activity
AltI4_12260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AltI4_12270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AltI4_12280	COG0776	regulation of translation
AltI4_12290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AltI4_12370	COG0268	Binds directly to 16S ribosomal RNA
AltI4_12380	COG2239	Acts as a magnesium transporter
AltI4_12390	COG0728	peptidoglycan biosynthetic process
AltI4_12400	COG0196	riboflavin kinase activity
AltI4_12410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AltI4_12430	COG1047	Peptidyl-prolyl cis-trans
AltI4_12440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AltI4_12510	COG4681	YaeQ
AltI4_12590	COG3209	COG3209 Rhs family protein
AltI4_12630	COG1484	DNA-dependent DNA replication
AltI4_12640	COG4584	PFAM Integrase catalytic
AltI4_12710	COG1047	Peptidyl-prolyl cis-trans
AltI4_12730	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AltI4_12740	COG2030	dehydratase
AltI4_12760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AltI4_12770	COG1595	DNA-templated transcription, initiation
AltI4_12820	COG0681	Belongs to the peptidase S26 family
AltI4_12830	COG0571	ribonuclease III activity
AltI4_12840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AltI4_12860	COG0084	hydrolase, TatD family'
AltI4_12880	COG0560	Phosphoserine phosphatase
AltI4_12930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AltI4_12950	COG0488	(ABC) transporter
AltI4_12960	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AltI4_12990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AltI4_12990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AltI4_13020	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AltI4_13040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AltI4_13050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AltI4_13070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AltI4_13080	COG0142	geranyltranstransferase activity
AltI4_13090	COG1722	exodeoxyribonuclease VII activity
AltI4_13100	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AltI4_13120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AltI4_13150	COG4221	oxidoreductase activity
AltI4_13180	COG1595	DNA-templated transcription, initiation
AltI4_13190	COG3806	Anti-sigma factor
AltI4_13220	COG0564	pseudouridine synthase activity
AltI4_13240	COG0542	response to heat
AltI4_13270	COG1183	phosphatidylcholine synthase activity
AltI4_13280	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_13290	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_13320	COG0840	transmembrane signaling receptor activity
AltI4_13340	COG3220	belongs to the UPF0276 family
AltI4_13360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AltI4_13370	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AltI4_13390	COG0277	FAD linked oxidase domain protein
AltI4_13400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AltI4_13410	COG0326	Molecular chaperone. Has ATPase activity
AltI4_13420	COG1609	Transcriptional regulator
AltI4_13460	COG4206	TonB-dependent receptor
AltI4_13540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AltI4_13540	COG0140	phosphoribosyl-ATP diphosphatase activity
AltI4_13570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AltI4_13580	COG0131	Imidazoleglycerol-phosphate dehydratase
AltI4_13580	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AltI4_13590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AltI4_13600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AltI4_13610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AltI4_13670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AltI4_13710	COG0783	Belongs to the Dps family
AltI4_13780	COG3706	GGDEF domain
AltI4_13800	COG3008	intermembrane lipid transfer
AltI4_13810	COG2995	paraquat-inducible protein a
AltI4_13820	COG0017	Asparaginyl-tRNA synthetase
AltI4_13950	COG3340	Belongs to the peptidase S51 family
AltI4_13960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AltI4_13970	COG4139	cobalamin transport
AltI4_13990	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AltI4_14010	COG3530	Putative quorum-sensing-regulated virulence factor
AltI4_14020	COG5265	(ABC) transporter
AltI4_14030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AltI4_14040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AltI4_14050	COG3706	GGDEF domain
AltI4_14060	COG0745	RESPONSE REGULATOR receiver
AltI4_14080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AltI4_14090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AltI4_14110	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AltI4_14120	COG4948	Mandelate Racemase Muconate Lactonizing
AltI4_14160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AltI4_14170	COG0402	S-adenosylhomocysteine deaminase activity
AltI4_14180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AltI4_14220	COG4181	ATPase activity
AltI4_14230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AltI4_14260	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AltI4_14310	COG0702	epimerase
AltI4_14320	COG1733	regulation of RNA biosynthetic process
AltI4_14350	COG3507	Belongs to the glycosyl hydrolase 43 family
AltI4_14360	COG1090	epimerase
AltI4_14370	COG0628	permease
AltI4_14400	COG2205	protein histidine kinase activity
AltI4_14410	COG0745	RESPONSE REGULATOR receiver
AltI4_14430	COG2350	Protein conserved in bacteria
AltI4_14460	COG0134	indole-3-glycerol-phosphate synthase activity
AltI4_14460	COG0135	phosphoribosylanthranilate isomerase activity
AltI4_14470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AltI4_14490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AltI4_14500	COG0613	PHP domain protein
AltI4_14510	COG0009	L-threonylcarbamoyladenylate synthase
AltI4_14530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AltI4_14590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AltI4_14660	COG1714	RDD family
AltI4_14700	COG0386	Belongs to the glutathione peroxidase family
AltI4_14740	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AltI4_14750	COG0497	DNA recombination
AltI4_14780	COG5001	Diguanylate cyclase
AltI4_14780	COG3300	MHYT domain
AltI4_14820	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_14840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AltI4_14850	COG2610	gluconate transmembrane transporter activity
AltI4_14920	COG2205	protein histidine kinase activity
AltI4_14920	COG5002	protein histidine kinase activity
AltI4_14920	COG0784	Response regulator, receiver
AltI4_14930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AltI4_14950	COG0484	heat shock protein binding
AltI4_14970	COG3300	MHYT domain
AltI4_14970	COG5001	Diguanylate cyclase
AltI4_15010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AltI4_15020	COG0505	Belongs to the CarA family
AltI4_15030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AltI4_15040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AltI4_15060	COG0454	-acetyltransferase
AltI4_15080	COG3401	FG-GAP repeat protein
AltI4_15100	COG0659	secondary active sulfate transmembrane transporter activity
AltI4_15170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AltI4_15190	COG4974	Belongs to the 'phage' integrase family
AltI4_15210	COG0464	growth
AltI4_15240	COG1484	DNA-dependent DNA replication
AltI4_15250	COG4584	PFAM Integrase catalytic
AltI4_15270	COG0071	Belongs to the small heat shock protein (HSP20) family
AltI4_15280	COG1228	amidohydrolase
AltI4_15290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AltI4_15300	COG4535	Mg2 and Co2 transporter CorC
AltI4_15320	COG1702	phosphate starvation-inducible protein PhoH
AltI4_15340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AltI4_15360	COG1115	amino acid carrier protein
AltI4_15380	COG0012	GTP binding
AltI4_15430	COG2205	protein histidine kinase activity
AltI4_15430	COG0784	Response regulator, receiver
AltI4_15460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AltI4_15470	COG5001	Diguanylate cyclase
AltI4_15470	COG3300	MHYT domain
AltI4_15490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AltI4_15500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AltI4_15520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AltI4_15540	COG2890	protein-(glutamine-N5) methyltransferase activity
AltI4_15550	COG0784	Response regulator, receiver
AltI4_15550	COG3437	response regulator, receiver
AltI4_15560	COG3094	Invasion gene expression up-regulator, SirB
AltI4_15590	COG0583	DNA-binding transcription factor activity
AltI4_15610	COG2363	Small membrane protein
AltI4_15640	COG4191	Histidine kinase
AltI4_15820	COG2204	response regulator
AltI4_15840	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AltI4_15960	COG1199	ATP-dependent helicase activity
AltI4_15970	COG1214	PFAM Peptidase M22, glycoprotease
AltI4_16010	COG0318	PFAM AMP-dependent synthetase and ligase
AltI4_16020	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AltI4_16040	COG2951	lytic endotransglycosylase activity
AltI4_16050	COG0179	Fumarylacetoacetate (FAA) hydrolase
AltI4_16060	COG2983	Belongs to the UPF0260 family
AltI4_16080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AltI4_16100	COG2186	Transcriptional regulator
AltI4_16170	COG4399	Belongs to the UPF0754 family
AltI4_16200	COG2226	methyltransferase
AltI4_16260	COG3072	Adenylate cyclase
AltI4_16280	COG1309	transcriptional regulator
AltI4_16290	COG1902	pentaerythritol trinitrate reductase activity
AltI4_16290	COG0446	pyridine nucleotide-disulphide oxidoreductase
AltI4_16330	COG3101	peptidyl-lysine hydroxylation
AltI4_16390	COG2026	Addiction module toxin, RelE StbE family
AltI4_16440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AltI4_16440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AltI4_16460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AltI4_16510	COG0101	tRNA pseudouridine synthase activity
AltI4_16530	COG0285	dihydrofolate synthase activity
AltI4_16540	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AltI4_16550	COG1286	toxin biosynthetic process
AltI4_16560	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AltI4_16630	COG1785	Belongs to the alkaline phosphatase family
AltI4_16640	COG1785	Belongs to the alkaline phosphatase family
AltI4_16650	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AltI4_16660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AltI4_16670	COG0215	cysteine-tRNA ligase activity
AltI4_16680	COG3344	reverse transcriptase
AltI4_16700	COG2204	response regulator
AltI4_16710	COG4206	TonB-dependent receptor
AltI4_16730	COG0471	metal ion transport
AltI4_16740	COG0281	malic enzyme
AltI4_16770	COG1388	LysM domain
AltI4_16770	COG0741	lytic transglycosylase activity
AltI4_16780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AltI4_16790	COG2226	methyltransferase
AltI4_16800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AltI4_16800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AltI4_16830	COG1082	Xylose isomerase domain protein TIM barrel
AltI4_16860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AltI4_16870	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AltI4_16880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AltI4_16890	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AltI4_16910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AltI4_16930	COG1451	nucleotide metabolic process
AltI4_16940	COG3706	GGDEF domain
AltI4_16980	COG0488	(ABC) transporter
AltI4_17010	COG0318	PFAM AMP-dependent synthetase and ligase
AltI4_17030	COG1620	l-lactate permease
AltI4_17050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AltI4_17080	COG2814	Major facilitator Superfamily
AltI4_17100	COG0798	PFAM Bile acid sodium symporter
AltI4_17110	COG0431	NADPH-dependent FMN reductase
AltI4_17130	COG0640	Transcriptional regulator
AltI4_17220	COG0583	DNA-binding transcription factor activity
AltI4_17230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AltI4_17250	COG2159	amidohydrolase
AltI4_17280	COG0667	Aldo Keto reductase
AltI4_17290	COG3384	dioxygenase
AltI4_17300	COG4771	TonB-dependent receptor
AltI4_17330	COG2871	sodium ion transport
AltI4_17350	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AltI4_17380	COG0277	FAD linked oxidase domain protein
AltI4_17400	COG2823	Periplasmic or secreted lipoprotein
AltI4_17430	COG2853	Lipoprotein
AltI4_17490	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AltI4_17510	COG0784	Response regulator, receiver
AltI4_17510	COG5002	protein histidine kinase activity
AltI4_17510	COG2198	Histidine kinase
AltI4_17520	COG0784	Response regulator, receiver
AltI4_17530	COG4251	negative regulation of phosphorylation
AltI4_17550	COG2204	response regulator
AltI4_17580	COG0640	Transcriptional regulator
AltI4_17610	COG0583	DNA-binding transcription factor activity
AltI4_17640	COG3300	MHYT domain
AltI4_17640	COG5001	Diguanylate cyclase
AltI4_17650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AltI4_17650	COG2010	Cytochrome c
AltI4_17670	COG1022	Amp-dependent synthetase and ligase
AltI4_17710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AltI4_17720	COG1074	ATP-dependent DNA helicase activity
AltI4_17730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AltI4_17790	COG0521	Mo-molybdopterin cofactor biosynthetic process
AltI4_17800	COG0315	cyclic pyranopterin monophosphate synthase activity
AltI4_17810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AltI4_17820	COG0314	molybdopterin synthase activity
AltI4_17850	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AltI4_17860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AltI4_17870	COG4771	TonB-dependent receptor
AltI4_17900	COG3706	GGDEF domain
AltI4_17930	COG0668	transmembrane transport
AltI4_17960	COG2198	Histidine kinase
AltI4_17960	COG5002	protein histidine kinase activity
AltI4_17960	COG0784	Response regulator, receiver
AltI4_17970	COG3437	response regulator, receiver
AltI4_17990	COG0195	Participates in both transcription termination and antitermination
AltI4_18020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AltI4_18040	COG0840	transmembrane signaling receptor activity
AltI4_18080	COG3153	acetyltransferase
AltI4_18080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AltI4_18110	COG0450	alkyl hydroperoxide reductase
AltI4_18120	COG3634	alkyl hydroperoxide reductase activity
AltI4_18160	COG1032	radical SAM domain protein
AltI4_18200	COG4948	Mandelate Racemase Muconate Lactonizing
AltI4_18220	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AltI4_18250	COG2733	membrane
AltI4_18260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AltI4_18270	COG0577	efflux transmembrane transporter activity
AltI4_18270	COG1136	(ABC) transporter
AltI4_18290	COG4667	esterase of the alpha-beta hydrolase superfamily
AltI4_18330	COG0415	Belongs to the DNA photolyase family
AltI4_18340	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AltI4_18400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AltI4_18450	COG1196	nuclear chromosome segregation
AltI4_18530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AltI4_18570	COG3668	Plasmid stabilization system
AltI4_18650	COG1484	DNA-dependent DNA replication
AltI4_18660	COG4584	PFAM Integrase catalytic
AltI4_18860	COG3608	succinylglutamate desuccinylase aspartoacylase
AltI4_18860	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AltI4_18890	COG2867	negative regulation of translational initiation
AltI4_18900	COG2914	Belongs to the UPF0125 (RnfH) family
AltI4_18920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AltI4_18930	COG4771	TonB-dependent receptor
AltI4_18940	COG0457	Tetratricopeptide repeat
AltI4_18960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AltI4_18960	COG0574	Belongs to the PEP-utilizing enzyme family
AltI4_19020	COG0277	FAD linked oxidase domain protein
AltI4_19020	COG0247	lactate metabolic process
AltI4_19050	COG2850	peptidyl-arginine hydroxylation
AltI4_19070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AltI4_19080	COG2915	High frequency lysogenization protein hflD homolog
AltI4_19090	COG0482	sulfurtransferase activity
AltI4_19100	COG1187	pseudouridine synthase activity
AltI4_19130	COG1278	Cold shock
AltI4_19140	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AltI4_19150	COG0542	response to heat
AltI4_19160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AltI4_19170	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AltI4_19180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AltI4_19190	COG0492	ferredoxin-NADP+ reductase activity
AltI4_19200	COG3092	negative regulation of chromosome organization
AltI4_19210	COG3091	SprT-like family
AltI4_19220	COG0616	signal peptide processing
AltI4_19250	COG0778	Nitroreductase
AltI4_19260	COG0469	pyruvate kinase activity
AltI4_19270	COG1737	Transcriptional regulator
AltI4_19280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AltI4_19290	COG0363	glucosamine-6-phosphate deaminase activity
AltI4_19300	COG0129	dihydroxy-acid dehydratase activity
AltI4_19310	COG0837	glucose binding
AltI4_19320	COG0800	Aldolase
AltI4_19340	COG0676	glucose-6-phosphate 1-epimerase activity
AltI4_19360	COG1640	4-alpha-glucanotransferase
AltI4_19370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AltI4_19390	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AltI4_19430	COG2866	Carboxypeptidase
AltI4_19440	COG1115	amino acid carrier protein
AltI4_19460	COG3139	Protein of unknown function (DUF1315)
AltI4_19500	COG0252	asparaginase activity
AltI4_19550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AltI4_19560	COG0321	lipoyl(octanoyl) transferase activity
AltI4_19570	COG2921	Belongs to the UPF0250 family
AltI4_19580	COG1686	Belongs to the peptidase S11 family
AltI4_19590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AltI4_19600	COG0772	Belongs to the SEDS family
AltI4_19610	COG0768	penicillin binding
AltI4_19630	COG0799	negative regulation of ribosome biogenesis
AltI4_19640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AltI4_19670	COG0495	leucyl-tRNA aminoacylation
AltI4_19690	COG1067	ATP-dependent peptidase activity
AltI4_19710	COG1534	Rna-binding protein
AltI4_19720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AltI4_19730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AltI4_19740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AltI4_19750	COG0149	triose-phosphate isomerase activity
AltI4_19760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AltI4_19800	COG1597	lipid kinase activity
AltI4_19830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AltI4_19880	COG1185	polyribonucleotide nucleotidyltransferase activity
AltI4_19950	COG1196	nuclear chromosome segregation
AltI4_19970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AltI4_19990	COG0658	competence protein
AltI4_19990	COG2333	competence protein COMEC
AltI4_20000	COG1132	(ABC) transporter
AltI4_20010	COG1663	tetraacyldisaccharide 4'-kinase activity
AltI4_20020	COG2835	tetraacyldisaccharide 4'-kinase activity
AltI4_20090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AltI4_20100	COG0579	oxidoreductase
AltI4_20110	COG0435	Glutathione S-transferase
AltI4_20120	COG1741	Belongs to the pirin family
AltI4_20170	COG2009	succinate dehydrogenase
AltI4_20180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AltI4_20190	COG1053	succinate dehydrogenase
AltI4_20210	COG0567	Dehydrogenase, E1 component
AltI4_20220	COG0508	dehydrogenase complex catalyzes the overall conversion of
AltI4_20310	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AltI4_20340	COG0004	ammonium transporteR
AltI4_20360	COG0366	Alpha amylase catalytic
AltI4_20360	COG1874	Beta-galactosidase
AltI4_20370	COG1609	Transcriptional regulator
AltI4_20390	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_20400	COG2267	carboxylic ester hydrolase activity
AltI4_20410	COG0616	signal peptide processing
AltI4_20430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AltI4_20440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AltI4_20450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AltI4_20460	COG2084	Dehydrogenase
AltI4_20490	COG1960	acyl-CoA dehydrogenase activity
AltI4_20500	COG1024	Enoyl-CoA hydratase
AltI4_20520	COG3083	sulfuric ester hydrolase activity
AltI4_20530	COG3082	Protein of unknown function (DUF1414)
AltI4_20540	COG3081	Nucleoid-associated protein
AltI4_20600	COG3275	phosphorelay sensor kinase activity
AltI4_20610	COG3279	Response regulator of the LytR AlgR family
AltI4_20620	COG3693	PFAM glycoside hydrolase, family 10
AltI4_20630	COG0205	6-phosphofructokinase activity
AltI4_20670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_20670	COG2205	protein histidine kinase activity
AltI4_20690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AltI4_20740	COG0513	Belongs to the DEAD box helicase family
AltI4_20760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AltI4_20770	COG0583	DNA-binding transcription factor activity
AltI4_20780	COG2194	sulfuric ester hydrolase activity
AltI4_20820	COG0583	DNA-binding transcription factor activity
AltI4_20910	COG1484	DNA-dependent DNA replication
AltI4_20920	COG4584	PFAM Integrase catalytic
AltI4_21050	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_21140	COG3250	beta-galactosidase activity
AltI4_21320	COG0519	Catalyzes the synthesis of GMP from XMP
AltI4_21390	COG1760	l-serine dehydratase
AltI4_21410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AltI4_21440	COG1322	Protein conserved in bacteria
AltI4_21450	COG3706	GGDEF domain
AltI4_21480	COG1404	Belongs to the peptidase S8 family
AltI4_21500	COG0022	dehydrogenase e1 component
AltI4_21520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AltI4_21530	COG0515	serine threonine protein kinase
AltI4_21540	COG1946	Acyl-CoA thioesterase
AltI4_21550	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AltI4_21560	COG2715	membrane protein required for spore maturation
AltI4_21580	COG1956	GAF domain-containing protein
AltI4_21610	COG0793	Belongs to the peptidase S41A family
AltI4_21620	COG0733	neurotransmitter:sodium symporter activity
AltI4_21640	COG0308	aminopeptidase N
AltI4_21690	COG2902	Dehydrogenase
AltI4_21700	COG0167	dihydroorotate dehydrogenase activity
AltI4_21730	COG0488	(ABC) transporter
AltI4_21750	COG3130	regulation of translation
AltI4_21760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AltI4_21780	COG0415	Belongs to the DNA photolyase family
AltI4_21790	COG0415	Belongs to the DNA photolyase family
AltI4_21800	COG3046	protein related to deoxyribodipyrimidine photolyase
AltI4_21830	COG2308	Evidence 4 Homologs of previously reported genes of
AltI4_21850	COG1309	transcriptional regulator
AltI4_21860	COG0604	alcohol dehydrogenase
AltI4_21890	COG4771	TonB-dependent receptor
AltI4_21900	COG1472	Belongs to the glycosyl hydrolase 3 family
AltI4_21920	COG2972	Histidine kinase
AltI4_22010	COG0681	Belongs to the peptidase S26 family
AltI4_22020	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AltI4_22030	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AltI4_22040	COG2814	Major facilitator Superfamily
AltI4_22050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AltI4_22060	COG0668	transmembrane transport
AltI4_22080	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_22100	COG0318	PFAM AMP-dependent synthetase and ligase
AltI4_22120	COG0589	response to stress
AltI4_22130	COG0069	glutamate synthase activity
AltI4_22140	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AltI4_22160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AltI4_22160	COG4651	solute:proton antiporter activity
AltI4_22180	COG2193	ferroxidase activity
AltI4_22200	COG3278	Belongs to the heme-copper respiratory oxidase family
AltI4_22230	COG2010	Cytochrome c
AltI4_22250	COG2217	Heavy metal translocating P-type atpase
AltI4_22280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AltI4_22290	COG0589	response to stress
AltI4_22300	COG0037	tRNA processing
AltI4_22310	COG1752	Esterase of the alpha-beta hydrolase superfamily
AltI4_22350	COG1280	lysine exporter protein (LysE YggA)
AltI4_22360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AltI4_22370	COG2897	thiosulfate sulfurtransferase activity
AltI4_22390	COG0840	transmembrane signaling receptor activity
AltI4_22450	COG4584	PFAM Integrase catalytic
AltI4_22460	COG1484	DNA-dependent DNA replication
AltI4_22550	COG0322	excinuclease ABC activity
AltI4_22560	COG2197	response regulator
AltI4_22570	COG0670	Belongs to the BI1 family
AltI4_22580	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AltI4_22590	COG2923	Belongs to the DsrF TusC family
AltI4_22610	COG2920	part of a sulfur-relay system
AltI4_22640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AltI4_22660	COG1674	ftsk spoiiie
AltI4_22660	COG0531	amino acid
AltI4_22680	COG0686	Belongs to the AlaDH PNT family
AltI4_22690	COG0284	orotidine-5'-phosphate decarboxylase activity
AltI4_22700	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AltI4_22720	COG0776	regulation of translation
AltI4_22730	COG0539	negative regulation of cytoplasmic translation
AltI4_22740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AltI4_22760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AltI4_22770	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AltI4_22790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AltI4_22800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AltI4_22820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AltI4_22850	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AltI4_22860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AltI4_22880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AltI4_22930	COG4783	chaperone-mediated protein folding
AltI4_22940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AltI4_22950	COG1393	Belongs to the ArsC family
AltI4_22990	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AltI4_23020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AltI4_23040	COG1960	acyl-CoA dehydrogenase activity
AltI4_23050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AltI4_23100	COG3769	mannosylglycerate metabolic process
AltI4_23110	COG1215	transferase activity, transferring glycosyl groups
AltI4_23130	COG0303	'Molybdopterin
AltI4_23140	COG0534	Mate efflux family protein
AltI4_23170	COG2095	MarC family integral membrane protein
AltI4_23190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AltI4_23230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AltI4_23320	COG3011	Protein conserved in bacteria
AltI4_23350	COG0405	Gamma-glutamyltransferase
AltI4_23360	COG1024	Enoyl-CoA hydratase
AltI4_23410	COG2873	o-acetylhomoserine
AltI4_23440	COG1448	Aminotransferase
AltI4_23550	COG0596	Alpha beta hydrolase
AltI4_23580	COG0840	transmembrane signaling receptor activity
AltI4_23590	COG0735	belongs to the Fur family
AltI4_23600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AltI4_23610	COG1984	allophanate hydrolase subunit 2
AltI4_23620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AltI4_23630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AltI4_23640	COG2996	Protein conserved in bacteria
AltI4_23650	COG1765	OsmC-like protein
AltI4_23660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AltI4_23720	COG0436	Aminotransferase
AltI4_23730	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AltI4_23740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AltI4_23800	COG3012	SEC-C Motif Domain Protein
AltI4_23920	COG2610	gluconate transmembrane transporter activity
AltI4_23930	COG3265	gluconokinase activity
AltI4_23940	COG1609	Transcriptional regulator
AltI4_23950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AltI4_23970	COG0084	hydrolase, TatD family'
AltI4_24000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AltI4_24010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AltI4_24020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AltI4_24030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AltI4_24050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AltI4_24060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AltI4_24070	COG0416	fatty acid biosynthetic process
AltI4_24090	COG1399	metal-binding, possibly nucleic acid-binding protein
AltI4_24100	COG0424	maF-like protein
AltI4_24120	COG0564	pseudouridine synthase activity
AltI4_24130	COG1530	ribonuclease E activity
AltI4_24200	COG3384	dioxygenase
AltI4_24210	COG0435	Glutathione S-transferase
AltI4_24220	COG2259	Doxx family
AltI4_24230	COG0583	DNA-binding transcription factor activity
AltI4_24290	COG3122	Protein conserved in bacteria
AltI4_24300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AltI4_24310	COG3724	N-succinylarginine dihydrolase activity
AltI4_24330	COG1301	dicarboxylic acid transport
AltI4_24340	COG4591	ABC-type transport system involved in lipoprotein release permease component
AltI4_24380	COG1304	FMN binding
AltI4_24390	COG4952	isomerase
AltI4_24400	COG3347	Dehydrogenase
AltI4_24400	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_24450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AltI4_24460	COG0328	RNA-DNA hybrid ribonuclease activity
AltI4_24480	COG0604	alcohol dehydrogenase
AltI4_24480	COG3321	synthase
AltI4_24530	COG1643	Atp-dependent helicase
AltI4_24580	COG2925	Exonuclease
AltI4_24610	COG0183	Belongs to the thiolase family
AltI4_24620	COG0789	Transcriptional regulator
AltI4_24630	COG1960	acyl-CoA dehydrogenase activity
AltI4_24640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AltI4_24650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AltI4_24780	COG1639	'signal transduction protein
AltI4_24790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AltI4_24830	COG0708	Exodeoxyribonuclease III
AltI4_24860	COG2205	protein histidine kinase activity
AltI4_24870	COG0745	RESPONSE REGULATOR receiver
AltI4_24910	COG1671	Belongs to the UPF0178 family
AltI4_24930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AltI4_24950	COG0456	acetyltransferase
AltI4_25040	COG2267	carboxylic ester hydrolase activity
AltI4_25090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AltI4_25320	COG4584	PFAM Integrase catalytic
AltI4_25330	COG1484	DNA-dependent DNA replication
AltI4_25560	COG4591	ABC-type transport system involved in lipoprotein release permease component
AltI4_25580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AltI4_25600	COG2096	Adenosyltransferase
AltI4_25620	COG0471	metal ion transport
AltI4_25640	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AltI4_25680	COG0072	phenylalanine-tRNA ligase activity
AltI4_25680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AltI4_25710	COG4774	siderophore transport
AltI4_25780	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AltI4_25830	COG0745	RESPONSE REGULATOR receiver
AltI4_25840	COG0642	Histidine kinase
AltI4_25900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AltI4_25930	COG1477	protein flavinylation
AltI4_25940	COG0583	DNA-binding transcription factor activity
AltI4_25960	COG0659	secondary active sulfate transmembrane transporter activity
AltI4_26000	COG0730	response to heat
AltI4_26010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AltI4_26040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AltI4_26050	COG2233	PERMEase
AltI4_26080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AltI4_26090	COG2252	PERMEase
AltI4_26110	COG1309	transcriptional regulator
AltI4_26130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AltI4_26160	COG2351	hydroxyisourate hydrolase activity
AltI4_26170	COG0402	S-adenosylhomocysteine deaminase activity
AltI4_26190	COG3447	MASE1 domain protein
AltI4_26190	COG5001	Diguanylate cyclase
AltI4_26190	COG5002	protein histidine kinase activity
AltI4_26200	COG4191	Histidine kinase
AltI4_26200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_26230	COG0746	molybdenum cofactor guanylyltransferase activity
AltI4_26250	COG1116	anion transmembrane transporter activity
AltI4_26270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AltI4_26280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AltI4_26290	COG1648	precorrin-2 dehydrogenase activity
AltI4_26290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AltI4_26300	COG0243	molybdopterin cofactor binding
AltI4_26310	COG2146	nitrite reductase [NAD(P)H] activity
AltI4_26320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AltI4_26320	COG2146	nitrite reductase [NAD(P)H] activity
AltI4_26350	COG3707	response regulator
AltI4_26470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AltI4_26500	COG0778	Nitroreductase
AltI4_26530	COG1960	acyl-CoA dehydrogenase activity
AltI4_26540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AltI4_26550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AltI4_26620	COG1845	cytochrome c oxidase, subunit III
AltI4_26650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AltI4_26820	COG1845	cytochrome c oxidase, subunit III
AltI4_26830	COG1012	belongs to the aldehyde dehydrogenase family
AltI4_26860	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_26930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AltI4_26950	COG2301	Belongs to the HpcH HpaI aldolase family
AltI4_26960	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AltI4_26970	COG1250	3-hydroxyacyl-CoA dehydrogenase
AltI4_26980	COG1024	Enoyl-CoA hydratase
AltI4_26990	COG1024	Enoyl-CoA hydratase
AltI4_27000	COG0183	Belongs to the thiolase family
AltI4_27060	COG4584	PFAM Integrase catalytic
AltI4_27070	COG1484	DNA-dependent DNA replication
AltI4_27080	COG0633	Ferredoxin
AltI4_27100	COG4771	TonB-dependent receptor
AltI4_27160	COG2190	(PTS) system
AltI4_27170	COG1393	Belongs to the ArsC family
AltI4_27210	COG0393	Putative heavy-metal-binding
AltI4_27230	COG2988	succinylglutamate desuccinylase activity
AltI4_27250	COG3385	transposase activity
AltI4_27260	COG0058	SHG alpha-glucan phosphorylase activity
AltI4_27270	COG0033	Phosphoglucomutase
AltI4_27280	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AltI4_27290	COG0714	Associated with various cellular activities
AltI4_27320	COG2205	protein histidine kinase activity
AltI4_27350	COG0577	efflux transmembrane transporter activity
AltI4_27350	COG1136	(ABC) transporter
AltI4_27370	COG0793	Belongs to the peptidase S41A family
AltI4_27370	COG4946	Tricorn protease homolog
AltI4_27470	COG2274	protein secretion by the type I secretion system
AltI4_27480	COG0583	DNA-binding transcription factor activity
AltI4_27550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AltI4_27570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AltI4_27580	COG0438	transferase activity, transferring glycosyl groups
AltI4_27610	COG0438	transferase activity, transferring glycosyl groups
AltI4_27620	COG1215	transferase activity, transferring glycosyl groups
AltI4_27650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AltI4_27660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AltI4_27670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AltI4_27690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AltI4_27700	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AltI4_27710	COG2885	chlorophyll binding
AltI4_27720	COG0823	Involved in the tonB-independent uptake of proteins
AltI4_27750	COG0811	peptide transport
AltI4_27760	COG0824	Thioesterase
AltI4_27770	COG2130	NADP-dependent
AltI4_27790	COG2255	four-way junction helicase activity
AltI4_27820	COG0494	nUDIX hydrolase
AltI4_27830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AltI4_27860	COG2204	response regulator
AltI4_27880	COG2205	protein histidine kinase activity
AltI4_27960	COG0023	Translation Initiation Factor
AltI4_27970	COG0745	RESPONSE REGULATOR receiver
AltI4_27980	COG1605	Chorismate mutase
AltI4_27980	COG0077	Prephenate dehydratase
AltI4_27990	COG0287	Prephenate dehydrogenase
AltI4_27990	COG1605	Chorismate mutase
AltI4_28000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AltI4_28010	COG1136	(ABC) transporter
AltI4_28050	COG0577	efflux transmembrane transporter activity
AltI4_28050	COG1136	(ABC) transporter
AltI4_28100	COG0335	large ribosomal subunit rRNA binding
AltI4_28110	COG0336	Belongs to the RNA methyltransferase TrmD family
AltI4_28120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AltI4_28130	COG0228	four-way junction DNA binding
AltI4_28140	COG1132	(ABC) transporter
AltI4_28160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AltI4_28240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AltI4_28250	COG4137	Cytochrome C assembly protein
AltI4_28260	COG4536	flavin adenine dinucleotide binding
AltI4_28330	COG1024	Enoyl-CoA hydratase
AltI4_28330	COG1250	3-hydroxyacyl-CoA dehydrogenase
AltI4_28350	COG0714	Associated with various cellular activities
AltI4_28420	COG1595	DNA-templated transcription, initiation
AltI4_28440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AltI4_28450	COG0175	sulfate reduction
AltI4_28460	COG0529	Catalyzes the synthesis of activated sulfate
AltI4_28470	COG1218	3'(2'),5'-bisphosphate nucleotidase
AltI4_28490	COG0471	metal ion transport
AltI4_28490	COG3273	potassium ion transport
AltI4_28500	COG0745	RESPONSE REGULATOR receiver
AltI4_28500	COG3706	GGDEF domain
AltI4_28540	COG1501	Belongs to the glycosyl hydrolase 31 family
AltI4_28550	COG1874	Beta-galactosidase
AltI4_28610	COG3344	reverse transcriptase
AltI4_28620	COG1668	transmembrane transport
AltI4_28630	COG4555	ABC transporter
AltI4_28670	COG0367	asparagine synthase
AltI4_28690	COG0602	queuosine metabolic process
AltI4_28730	COG4628	conserved protein (DUF2132)
AltI4_28740	COG0556	nucleotide-excision repair
AltI4_28750	COG0534	Mate efflux family protein
AltI4_28760	COG4657	Part of a membrane complex involved in electron transport
AltI4_28770	COG2878	Part of a membrane complex involved in electron transport
AltI4_28780	COG4656	Part of a membrane complex involved in electron transport
AltI4_28790	COG4658	electron transport chain
AltI4_28800	COG4659	FMN binding
AltI4_28810	COG4660	Part of a membrane complex involved in electron transport
AltI4_28820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AltI4_28870	COG0346	lactoylglutathione lyase activity
AltI4_28880	COG0584	glycerophosphoryl diester phosphodiesterase
AltI4_28900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AltI4_28910	COG0477	Major facilitator Superfamily
AltI4_28910	COG2814	Major facilitator Superfamily
AltI4_28920	COG0450	alkyl hydroperoxide reductase
AltI4_28970	COG4771	TonB-dependent receptor
AltI4_28980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AltI4_29000	COG2766	serine protein kinase
AltI4_29010	COG2718	Belongs to the UPF0229 family
AltI4_29020	COG2719	SpoVR family
AltI4_29030	COG2814	Major facilitator Superfamily
AltI4_29050	COG2890	protein-(glutamine-N5) methyltransferase activity
AltI4_29060	COG2840	Smr protein MutS2
AltI4_29110	COG0612	Peptidase, M16
AltI4_29130	COG0564	pseudouridine synthase activity
AltI4_29140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AltI4_29150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AltI4_29280	COG4774	siderophore transport
AltI4_29300	COG1607	acyl-coa hydrolase
AltI4_29340	COG0848	biopolymer transport protein
AltI4_29350	COG0811	peptide transport
AltI4_29360	COG0811	peptide transport
AltI4_29420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AltI4_29430	COG1522	sequence-specific DNA binding
AltI4_29440	COG0625	glutathione transferase activity
AltI4_29460	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AltI4_29520	COG1842	Phage shock protein A
AltI4_29530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AltI4_29540	COG0747	negative chemotaxis
AltI4_29550	COG4168	peptide transport system, permease
AltI4_29560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AltI4_29570	COG4172	Belongs to the ABC transporter superfamily
AltI4_29580	COG4608	Belongs to the ABC transporter superfamily
AltI4_29590	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AltI4_29620	COG1476	TRANSCRIPTIONal
AltI4_29660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AltI4_29670	COG2137	regulation of response to DNA damage stimulus
AltI4_29690	COG3590	peptidase
AltI4_29710	COG0646	methionine synthase
AltI4_29710	COG1410	methionine synthase
AltI4_29720	COG0646	methionine synthase
AltI4_29720	COG1410	methionine synthase
AltI4_29760	COG0835	chemotaxis
AltI4_29780	COG1192	Involved in chromosome partitioning
AltI4_29790	COG2201	protein-glutamate methylesterase activity
AltI4_29800	COG0643	Histidine kinase
AltI4_29800	COG2198	Histidine kinase
AltI4_29810	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AltI4_29840	COG0455	bacterial-type flagellum organization
AltI4_29860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AltI4_29890	COG1987	bacterial-type flagellum assembly
AltI4_29910	COG3190	flagellar
AltI4_29990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AltI4_30000	COG1766	The M ring may be actively involved in energy transduction
AltI4_30010	COG1677	Flagellar hook-basal body complex protein FliE
AltI4_30020	COG2204	response regulator
AltI4_30030	COG3852	Histidine kinase
AltI4_30040	COG2204	response regulator
AltI4_30120	COG1660	Displays ATPase and GTPase activities
AltI4_30130	COG1216	Glycosyl transferase, family 2
AltI4_30150	COG1216	Glycosyl transferase, family 2
AltI4_30180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AltI4_30190	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_30230	COG2089	acid synthase
AltI4_30240	COG1083	cytidylyl-transferase
AltI4_30250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AltI4_30260	COG1086	Polysaccharide biosynthesis protein
AltI4_30340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AltI4_30380	COG1256	bacterial-type flagellum assembly
AltI4_30390	COG3951	Flagellar rod assembly protein muramidase FlgJ
AltI4_30390	COG1705	Flagellar rod assembly protein muramidase FlgJ
AltI4_30420	COG4786	Flagellar basal body rod
AltI4_30430	COG4787	bacterial-type flagellum-dependent cell motility
AltI4_30440	COG1749	Flagellar hook protein flgE
AltI4_30450	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AltI4_30460	COG1558	bacterial-type flagellum-dependent cell motility
AltI4_30470	COG1815	bacterial-type flagellum-dependent cell motility
AltI4_30480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AltI4_30490	COG0835	chemotaxis
AltI4_30490	COG0784	Response regulator, receiver
AltI4_30630	COG0590	tRNA wobble adenosine to inosine editing
AltI4_30660	COG5001	Diguanylate cyclase
AltI4_30670	COG0037	tRNA processing
AltI4_30680	COG0825	malonyl-CoA metabolic process
AltI4_30720	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AltI4_30730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AltI4_30760	COG0750	zinc metalloprotease
AltI4_30770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AltI4_30780	COG0575	Belongs to the CDS family
AltI4_30790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AltI4_30810	COG0528	UMP kinase activity
AltI4_30830	COG0052	Belongs to the universal ribosomal protein uS2 family
AltI4_30840	COG0024	Methionine aminopeptidase
AltI4_30890	COG3098	single-species biofilm formation
AltI4_30940	COG4584	PFAM Integrase catalytic
AltI4_30950	COG1484	DNA-dependent DNA replication
AltI4_31110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AltI4_31110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AltI4_31120	COG3706	GGDEF domain
AltI4_31130	COG1611	Belongs to the LOG family
AltI4_31160	COG0473	3-isopropylmalate dehydrogenase activity
AltI4_31170	COG1596	polysaccharide export
AltI4_31170	COG1555	photosystem II stabilization
AltI4_31180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AltI4_31190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AltI4_31200	COG1862	Preprotein translocase
AltI4_31210	COG0343	queuine tRNA-ribosyltransferase activity
AltI4_31250	COG1842	Phage shock protein A
AltI4_31300	COG0754	glutathionylspermidine amidase activity
AltI4_31330	COG1785	Belongs to the alkaline phosphatase family
AltI4_31530	COG0367	asparagine synthase
AltI4_31540	COG0438	transferase activity, transferring glycosyl groups
AltI4_31550	COG1796	DNA polymerase
AltI4_31550	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AltI4_31570	COG2244	polysaccharide biosynthetic process
AltI4_31620	COG2755	lipolytic protein G-D-S-L family
AltI4_31620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AltI4_31630	COG1216	Glycosyl transferase, family 2
AltI4_31640	COG2755	lipolytic protein G-D-S-L family
AltI4_31640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AltI4_31680	COG1215	transferase activity, transferring glycosyl groups
AltI4_31710	COG0438	transferase activity, transferring glycosyl groups
AltI4_31720	COG0438	transferase activity, transferring glycosyl groups
AltI4_31800	COG0489	protein tyrosine kinase activity
AltI4_31820	COG3409	Peptidoglycan-binding domain 1 protein
AltI4_31820	COG3267	Type II secretory pathway component ExeA
AltI4_31830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AltI4_31830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AltI4_31840	COG2827	Endonuclease containing a URI domain
AltI4_31880	COG1560	Kdo2-lipid A biosynthetic process
AltI4_31920	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AltI4_31930	COG1960	acyl-CoA dehydrogenase activity
AltI4_31940	COG5001	Diguanylate cyclase
AltI4_31940	COG3300	MHYT domain
AltI4_31950	COG1435	thymidine kinase activity
AltI4_32030	COG1609	Transcriptional regulator
AltI4_32040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AltI4_32070	COG3300	MHYT domain
AltI4_32070	COG5001	Diguanylate cyclase
AltI4_32080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AltI4_32110	COG0308	aminopeptidase N
AltI4_32130	COG0657	acetylesterase activity
AltI4_32130	COG2755	lipolytic protein G-D-S-L family
AltI4_32170	COG1607	acyl-coa hydrolase
AltI4_32260	COG0583	DNA-binding transcription factor activity
AltI4_32290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AltI4_32300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AltI4_32310	COG0006	proline dipeptidase activity
AltI4_32320	COG3079	Belongs to the UPF0149 family
AltI4_32330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AltI4_32350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AltI4_32360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AltI4_32370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AltI4_32410	COG3313	Fe-S protein
AltI4_32440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AltI4_32450	COG0508	dehydrogenase complex catalyzes the overall conversion of
AltI4_32470	COG2186	Transcriptional regulator
AltI4_32500	COG3577	Aspartyl protease
AltI4_32520	COG4969	Belongs to the N-Me-Phe pilin family
AltI4_32530	COG1459	type II secretion system
AltI4_32540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AltI4_32610	COG3608	succinylglutamate desuccinylase aspartoacylase
AltI4_32770	COG2986	histidine ammonia-lyase
AltI4_32850	COG0583	DNA-binding transcription factor activity
AltI4_32930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AltI4_32940	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AltI4_32960	COG3220	belongs to the UPF0276 family
AltI4_32980	COG3118	belongs to the thioredoxin family
AltI4_33080	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_33100	COG0583	DNA-binding transcription factor activity
AltI4_33130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AltI4_33190	COG0308	aminopeptidase N
AltI4_33200	COG0251	oxidation-reduction process
AltI4_33210	COG1739	Uncharacterized protein family UPF0029
AltI4_33230	COG1272	protein, Hemolysin III
AltI4_33240	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_33250	COG1764	response to oxidative stress
AltI4_33260	COG1846	Transcriptional regulator
AltI4_33360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AltI4_33370	COG0513	Belongs to the DEAD box helicase family
AltI4_33380	COG1278	Cold shock
AltI4_33410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AltI4_33440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AltI4_33450	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AltI4_33550	COG1216	Glycosyl transferase, family 2
AltI4_33590	COG2199	diguanylate cyclase activity
AltI4_33590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AltI4_33670	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_33720	COG1132	(ABC) transporter
AltI4_33740	COG1595	DNA-templated transcription, initiation
AltI4_33770	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_33790	COG0306	phosphate transporter
AltI4_33810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AltI4_33830	COG0573	inorganic phosphate transmembrane transporter activity
AltI4_33850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AltI4_33860	COG0248	Ppx GppA phosphatase
AltI4_33880	COG3588	fructose-bisphosphate aldolase
AltI4_33890	COG0126	phosphoglycerate kinase activity
AltI4_33910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AltI4_33930	COG2954	triphosphatase activity
AltI4_33950	COG1794	racemase activity, acting on amino acids and derivatives
AltI4_33980	COG0784	Response regulator, receiver
AltI4_33980	COG2205	protein histidine kinase activity
AltI4_34110	COG1741	Belongs to the pirin family
AltI4_34120	COG0583	DNA-binding transcription factor activity
AltI4_34140	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AltI4_34160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AltI4_34190	COG5007	Belongs to the BolA IbaG family
AltI4_34210	COG2854	intermembrane phospholipid transfer
AltI4_34220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AltI4_34230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AltI4_34240	COG1127	ABC transporter
AltI4_34260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AltI4_34260	COG0517	IMP dehydrogenase activity
AltI4_34270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AltI4_34300	COG1137	ATPase activity
AltI4_34310	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AltI4_34330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AltI4_34350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AltI4_34360	COG3300	MHYT domain
AltI4_34360	COG5001	Diguanylate cyclase
AltI4_34370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AltI4_34390	COG4682	membrane
AltI4_34440	COG2239	Acts as a magnesium transporter
AltI4_34450	COG0745	RESPONSE REGULATOR receiver
AltI4_34480	COG2969	positive regulation of protein catabolic process
AltI4_34490	COG0625	glutathione transferase activity
AltI4_34500	COG2857	Cytochrome c1
AltI4_34510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AltI4_34520	COG0723	plastoquinol--plastocyanin reductase activity
AltI4_34540	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AltI4_34570	COG3956	TIGRFAM MazG family protein
AltI4_34580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AltI4_34590	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AltI4_34610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AltI4_34640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AltI4_34650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AltI4_34660	COG4974	Belongs to the 'phage' integrase family
AltI4_34670	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AltI4_34680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AltI4_34690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AltI4_34700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AltI4_34720	COG2967	ApaG domain
AltI4_34810	COG3706	GGDEF domain
AltI4_34830	COG2203	Gaf domain
AltI4_34830	COG3706	GGDEF domain
AltI4_34830	COG4251	negative regulation of phosphorylation
AltI4_34830	COG5001	Diguanylate cyclase
AltI4_34840	COG0527	aspartate kinase activity
AltI4_34870	COG2133	pyrroloquinoline quinone binding
AltI4_34940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AltI4_34950	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AltI4_34970	COG4325	translation initiation factor activity
AltI4_35020	COG0848	biopolymer transport protein
AltI4_35030	COG0811	peptide transport
AltI4_35040	COG0811	peptide transport
AltI4_35100	COG5002	protein histidine kinase activity
AltI4_35110	COG0745	RESPONSE REGULATOR receiver
AltI4_35120	COG4191	Histidine kinase
AltI4_35120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_35130	COG2974	May be involved in recombination
AltI4_35140	COG2311	Membrane
AltI4_35150	COG1396	sequence-specific DNA binding
AltI4_35160	COG3135	benzoate transporter
AltI4_35190	COG0537	adenosine 5'-monophosphoramidase activity
AltI4_35230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AltI4_35250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AltI4_35310	COG0358	DNA primase activity
AltI4_35320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AltI4_35360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AltI4_35370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AltI4_35400	COG1960	acyl-CoA dehydrogenase activity
AltI4_35440	COG0348	domain, Protein
AltI4_35450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AltI4_35470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AltI4_35480	COG3710	Transcriptional regulator
AltI4_35520	COG0659	secondary active sulfate transmembrane transporter activity
AltI4_35570	COG0271	Belongs to the BolA IbaG family
AltI4_35720	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AltI4_35760	COG2234	aminopeptidase activity
AltI4_35830	COG0583	DNA-binding transcription factor activity
AltI4_35840	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AltI4_35860	COG1960	acyl-CoA dehydrogenase activity
AltI4_35870	COG1522	sequence-specific DNA binding
AltI4_35900	COG1278	Cold shock
AltI4_35910	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AltI4_35930	COG2226	methyltransferase
AltI4_35960	COG0339	signal peptide processing
AltI4_35970	COG2199	diguanylate cyclase activity
AltI4_35970	COG2200	EAL domain
AltI4_35970	COG2203	Gaf domain
AltI4_35980	COG2201	protein-glutamate methylesterase activity
AltI4_36000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_36000	COG4191	Histidine kinase
AltI4_36020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AltI4_36040	COG3437	response regulator, receiver
AltI4_36040	COG0784	Response regulator, receiver
AltI4_36050	COG0402	S-adenosylhomocysteine deaminase activity
AltI4_36090	COG1695	Transcriptional regulator
AltI4_36140	COG2197	response regulator
AltI4_36180	COG3093	addiction module antidote protein HigA
AltI4_36220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AltI4_36230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AltI4_36250	COG0281	malic enzyme
AltI4_36270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AltI4_36330	COG0456	acetyltransferase
AltI4_36350	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AltI4_36360	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AltI4_36370	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AltI4_36380	COG2177	Part of the ABC transporter FtsEX involved in
AltI4_36390	COG2884	Cell division ATP-binding protein ftsE
AltI4_36400	COG0552	protein localization to endoplasmic reticulum
AltI4_36410	COG0742	ribosomal rna small subunit methyltransferase
AltI4_36420	COG3068	Protein conserved in bacteria
AltI4_36430	COG2095	MarC family integral membrane protein
AltI4_36470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AltI4_36480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AltI4_36490	COG0617	tRNA 3'-terminal CCA addition
AltI4_36520	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AltI4_36530	COG0784	Response regulator, receiver
AltI4_36530	COG2205	protein histidine kinase activity
AltI4_36540	COG0076	glutamate decarboxylase activity
AltI4_36550	COG4106	trans-aconitate 2-methyltransferase activity
AltI4_36560	COG0842	Transport permease protein
AltI4_36570	COG1131	(ABC) transporter
AltI4_36580	COG5002	protein histidine kinase activity
AltI4_36580	COG0784	Response regulator, receiver
AltI4_36580	COG2205	protein histidine kinase activity
AltI4_36590	COG0745	RESPONSE REGULATOR receiver
AltI4_36590	COG3706	GGDEF domain
AltI4_36600	COG2885	chlorophyll binding
AltI4_36600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AltI4_36610	COG0745	RESPONSE REGULATOR receiver
AltI4_36620	COG2205	protein histidine kinase activity
AltI4_36630	COG1253	flavin adenine dinucleotide binding
AltI4_36640	COG1966	Carbon starvation protein
AltI4_36650	COG3300	MHYT domain
AltI4_36650	COG5001	Diguanylate cyclase
AltI4_36690	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AltI4_36700	COG0049	tRNA binding
AltI4_36710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AltI4_36720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AltI4_36730	COG0085	RNA polymerase activity
AltI4_36740	COG0222	ribosome binding
AltI4_36750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AltI4_36760	COG0081	regulation of translation
AltI4_36770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AltI4_36780	COG0250	Participates in transcription elongation, termination and antitermination
AltI4_36790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AltI4_36810	COG1960	acyl-CoA dehydrogenase activity
AltI4_36830	COG1132	(ABC) transporter
AltI4_36840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AltI4_36860	COG0251	oxidation-reduction process
AltI4_36870	COG2010	Cytochrome c
AltI4_36910	COG0513	Belongs to the DEAD box helicase family
AltI4_36920	COG0418	dihydroorotase activity
AltI4_36930	COG0243	molybdopterin cofactor binding
AltI4_36960	COG3040	lipid binding
AltI4_36970	COG4989	oxidoreductase activity
AltI4_36980	COG0346	lactoylglutathione lyase activity
AltI4_36990	COG1940	carbohydrate kinase activity
AltI4_37000	COG2211	Major facilitator Superfamily
AltI4_37030	COG0302	gtp cyclohydrolase
AltI4_37040	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_37050	COG2957	Belongs to the agmatine deiminase family
AltI4_37080	COG1201	RNA secondary structure unwinding
AltI4_37120	COG1793	dna ligase
AltI4_37140	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_37210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AltI4_37230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AltI4_37240	COG3706	GGDEF domain
AltI4_37240	COG0745	RESPONSE REGULATOR receiver
AltI4_37260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AltI4_37270	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AltI4_37280	COG0330	HflC and HflK could
AltI4_37290	COG0330	HflC and HflK could
AltI4_37300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AltI4_37310	COG1923	regulation of RNA biosynthetic process
AltI4_37320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AltI4_37350	COG0802	atpase or kinase
AltI4_37360	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AltI4_37360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AltI4_37370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AltI4_37380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AltI4_37410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AltI4_37420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AltI4_37440	COG2022	thiamine diphosphate biosynthetic process
AltI4_37470	COG0351	phosphomethylpyrimidine kinase
AltI4_37500	COG1522	sequence-specific DNA binding
AltI4_37530	COG0735	belongs to the Fur family
AltI4_37550	COG0432	Pfam Uncharacterised protein family UPF0047
AltI4_37570	COG0305	Participates in initiation and elongation during chromosome replication
AltI4_37660	COG2258	MOSC domain
AltI4_37920	COG2211	Major facilitator Superfamily
AltI4_37940	COG0673	inositol 2-dehydrogenase activity
AltI4_37950	COG1609	Transcriptional regulator
AltI4_38050	COG2971	BadF BadG BcrA BcrD
AltI4_38060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AltI4_38070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AltI4_38090	COG0840	transmembrane signaling receptor activity
AltI4_38100	COG3547	Transposase (IS116 IS110 IS902 family)
AltI4_38110	COG1309	transcriptional regulator
AltI4_38120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AltI4_38130	COG1335	isochorismatase
AltI4_38140	COG0251	oxidation-reduction process
AltI4_38150	COG0596	Alpha beta hydrolase
AltI4_38160	COG0778	Nitroreductase
AltI4_38170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AltI4_38200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AltI4_38220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AltI4_38230	COG1349	DNA-binding transcription factor activity
AltI4_38250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AltI4_38260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AltI4_38290	COG1621	beta-fructofuranosidase activity
AltI4_38300	COG2814	Major facilitator Superfamily
AltI4_38360	COG1476	TRANSCRIPTIONal
AltI4_38390	COG3609	addiction module antidote protein, CC2985 family
AltI4_38420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AltI4_38460	COG1175	transmembrane transport
AltI4_38480	COG3659	wide pore channel activity
AltI4_38500	COG0246	Mannitol dehydrogenase
AltI4_38530	COG1595	DNA-templated transcription, initiation
AltI4_38580	COG0436	Aminotransferase
AltI4_38600	COG0626	cystathionine gamma-synthase activity
AltI4_38610	COG1757	Na H antiporter
AltI4_38630	COG0840	transmembrane signaling receptor activity
AltI4_38640	COG0348	domain, Protein
AltI4_38650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AltI4_38720	COG4774	siderophore transport
AltI4_38780	COG3275	phosphorelay sensor kinase activity
AltI4_38790	COG1131	(ABC) transporter
AltI4_38820	COG0604	alcohol dehydrogenase
AltI4_38830	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AltI4_38860	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AltI4_38880	COG0297	glycogen (starch) synthase activity
AltI4_38900	COG4191	Histidine kinase
AltI4_38900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AltI4_38910	COG0745	RESPONSE REGULATOR receiver
AltI4_38940	COG0312	modulator of DNA gyrase
AltI4_38950	COG3028	Belongs to the UPF0307 family
AltI4_38960	COG0312	modulator of DNA gyrase
AltI4_38970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AltI4_38980	COG3164	Protein of unknown function
AltI4_38990	COG1530	ribonuclease E activity
AltI4_39000	COG0424	maF-like protein
AltI4_39010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AltI4_39020	COG1792	Involved in formation and maintenance of cell shape
AltI4_39030	COG1077	Cell shape determining protein MreB Mrl
AltI4_39090	COG4969	Belongs to the N-Me-Phe pilin family
AltI4_39120	COG1459	type II secretion system
AltI4_39130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AltI4_39150	COG3409	Peptidoglycan-binding domain 1 protein
AltI4_39150	COG3267	Type II secretory pathway component ExeA
AltI4_39210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AltI4_39240	COG3243	poly(R)-hydroxyalkanoic acid synthase
AltI4_39260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AltI4_39280	COG0189	ligase activity
AltI4_39300	COG1595	DNA-templated transcription, initiation
AltI4_39330	COG2239	Acts as a magnesium transporter
AltI4_39370	COG0629	single-stranded DNA binding
AltI4_39440	COG1674	ftsk spoiiie
AltI4_39440	COG1196	nuclear chromosome segregation
AltI4_39450	COG4191	Histidine kinase
AltI4_39470	COG1484	DNA-dependent DNA replication
AltI4_39480	COG4584	PFAM Integrase catalytic
AltI4_39530	COG1104	cysteine desulfurase activity
AltI4_39620	COG3250	beta-galactosidase activity
AltI4_39630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AltI4_39700	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AltI4_39710	COG1085	galactose-1-phosphate uridylyltransferase
AltI4_39730	COG1609	Transcriptional regulator
AltI4_39770	COG2186	Transcriptional regulator
AltI4_39800	COG4771	TonB-dependent receptor
AltI4_39820	COG3940	Belongs to the glycosyl hydrolase 43 family
AltI4_39830	COG3507	Belongs to the glycosyl hydrolase 43 family
AltI4_39840	COG0471	metal ion transport
AltI4_39840	COG0490	domain, Protein
AltI4_39860	COG3866	Pectate lyase
AltI4_39890	COG1349	DNA-binding transcription factor activity
AltI4_39900	COG2223	nitrite transmembrane transporter activity
AltI4_39950	COG0523	cobalamin synthesis protein
AltI4_39970	COG0577	efflux transmembrane transporter activity
AltI4_39970	COG1136	(ABC) transporter
AltI4_40040	COG0545	Peptidyl-prolyl cis-trans isomerase
AltI4_40110	COG1279	arginine transmembrane transporter activity
AltI4_40160	COG3668	Plasmid stabilization system
AltI4_40210	COG3940	Belongs to the glycosyl hydrolase 43 family
AltI4_40220	COG2211	Major facilitator Superfamily
AltI4_40240	COG3507	Belongs to the glycosyl hydrolase 43 family
AltI4_40280	COG4774	siderophore transport
AltI4_40310	COG3940	Belongs to the glycosyl hydrolase 43 family
AltI4_40320	COG1082	Xylose isomerase domain protein TIM barrel
AltI4_40340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AltI4_40380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AltI4_40390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AltI4_40400	COG0346	lactoylglutathione lyase activity
AltI4_40430	COG2814	Major facilitator Superfamily
AltI4_40440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AltI4_40480	COG0004	ammonium transporteR
AltI4_40490	COG3507	Belongs to the glycosyl hydrolase 43 family
AltI4_40530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AltI4_40540	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AltI4_40550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AltI4_40560	COG0163	prenyltransferase activity
AltI4_40590	COG0671	phosphoesterase, PA-phosphatase related
AltI4_40610	COG0019	diaminopimelate decarboxylase activity
AltI4_40620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AltI4_40650	COG1011	Hydrolase
AltI4_40670	COG0210	DNA helicase
AltI4_40680	COG0745	RESPONSE REGULATOR receiver
AltI4_40680	COG3706	GGDEF domain
AltI4_40700	COG0534	Mate efflux family protein
AltI4_40720	COG2962	Rard protein
AltI4_40730	COG2239	Acts as a magnesium transporter
AltI4_40740	COG0514	ATP-dependent DNA helicase (RecQ)
AltI4_40760	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AltI4_40790	COG3064	Membrane
AltI4_40820	COG3264	Mechanosensitive ion channel
AltI4_40820	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AltI4_40870	COG0123	including yeast histone deacetylase and acetoin utilization protein
AltI4_40880	COG0427	acetyl-CoA hydrolase
AltI4_40910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AltI4_41030	COG3038	cytochrome b561
AltI4_41080	COG1252	NADH dehydrogenase
AltI4_41100	COG1012	belongs to the aldehyde dehydrogenase family
AltI4_41120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AltI4_41150	COG0784	Response regulator, receiver
AltI4_41150	COG2205	protein histidine kinase activity
AltI4_41190	COG1131	(ABC) transporter
AltI4_41250	COG0348	domain, Protein
AltI4_41250	COG3901	Regulator of nitric oxide reductase transcription
AltI4_41270	COG3550	peptidyl-serine autophosphorylation
AltI4_41280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AltI4_41290	COG2205	protein histidine kinase activity
AltI4_41300	COG0745	RESPONSE REGULATOR receiver
AltI4_41310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AltI4_41330	COG1538	Outer membrane efflux protein
AltI4_41420	COG4774	siderophore transport
AltI4_41450	COG3706	GGDEF domain
AltI4_41480	COG5002	protein histidine kinase activity
AltI4_41490	COG0745	RESPONSE REGULATOR receiver
AltI4_41540	COG1505	serine-type exopeptidase activity
AltI4_41560	COG0583	DNA-binding transcription factor activity
AltI4_41570	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AltI4_41610	COG1522	sequence-specific DNA binding
AltI4_41620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AltI4_41700	COG1473	amidohydrolase
AltI4_41770	COG4172	Belongs to the ABC transporter superfamily
AltI4_41780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AltI4_41790	COG0601	transmembrane transport
AltI4_41810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AltI4_41850	COG1012	belongs to the aldehyde dehydrogenase family
AltI4_41920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AltI4_41930	COG1349	DNA-binding transcription factor activity
AltI4_41950	COG0673	inositol 2-dehydrogenase activity
AltI4_41960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AltI4_41970	COG2199	diguanylate cyclase activity
AltI4_41980	COG0697	spore germination
AltI4_41990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AltI4_42000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AltI4_42020	COG1166	arginine decarboxylase activity
AltI4_42070	COG1522	sequence-specific DNA binding
AltI4_42080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AltI4_42090	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AltI4_42100	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AltI4_42110	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AltI4_42120	COG0612	Peptidase, M16
AltI4_42130	COG3344	reverse transcriptase
AltI4_42160	COG4677	pectinesterase activity
AltI4_42200	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AltI4_42210	COG4771	TonB-dependent receptor
AltI4_42220	COG2755	lipolytic protein G-D-S-L family
AltI4_42230	COG3706	GGDEF domain
AltI4_42240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AltI4_42250	COG0800	Aldolase
AltI4_42260	COG0246	Mannitol dehydrogenase
AltI4_42270	COG1904	glucuronate isomerase
AltI4_42280	COG2721	sulfolactate sulfo-lyase activity
AltI4_42330	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AltI4_42340	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_42370	COG1324	tolerance protein
AltI4_42380	COG4232	protein-disulfide reductase activity
AltI4_42400	COG0840	transmembrane signaling receptor activity
AltI4_42430	COG0745	RESPONSE REGULATOR receiver
AltI4_42440	COG0643	Histidine kinase
AltI4_42440	COG2198	Histidine kinase
AltI4_42450	COG0835	chemotaxis
AltI4_42480	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AltI4_42490	COG2201	protein-glutamate methylesterase activity
AltI4_42500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AltI4_42510	COG0511	ligase activity, forming carbon-carbon bonds
AltI4_42520	COG0439	Biotin carboxylase
AltI4_42600	COG0154	amidase activity
AltI4_42630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AltI4_42660	COG0151	Belongs to the GarS family
AltI4_42690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AltI4_42700	COG3954	Phosphoribulokinase
AltI4_42710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AltI4_42720	COG0745	RESPONSE REGULATOR receiver
AltI4_42760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AltI4_42770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AltI4_42780	COG3031	protein transport across the cell outer membrane
AltI4_42800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AltI4_42810	COG1459	type II secretion system
AltI4_42820	COG2165	general secretion pathway protein
AltI4_42840	COG2165	general secretion pathway protein
AltI4_42850	COG4795	General secretion pathway protein
AltI4_42860	COG3156	type II secretion system protein K
AltI4_42880	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AltI4_42910	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AltI4_42920	COG1011	Hydrolase
AltI4_42930	COG0494	nUDIX hydrolase
AltI4_42940	COG1218	3'(2'),5'-bisphosphate nucleotidase
AltI4_42950	COG2353	YceI-like domain
AltI4_42970	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AltI4_43000	COG0429	hydrolase of the alpha beta-hydrolase fold
AltI4_43020	COG0488	(ABC) transporter
AltI4_43060	COG2268	Band 7 protein
AltI4_43070	COG1278	Cold shock
AltI4_43090	COG3177	Filamentation induced by cAMP protein fic
AltI4_43110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AltI4_43120	COG2900	Belongs to the SlyX family
AltI4_43140	COG0545	Peptidyl-prolyl cis-trans isomerase
AltI4_43160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AltI4_43200	COG2183	response to ionizing radiation
AltI4_43230	COG0596	Alpha beta hydrolase
AltI4_43240	COG1040	competence protein
AltI4_43270	COG0534	Mate efflux family protein
AltI4_43280	COG1649	PFAM Uncharacterised BCR, COG1649
AltI4_43280	COG0726	polysaccharide deacetylase
AltI4_43310	COG0109	protoheme IX farnesyltransferase activity
AltI4_43320	COG1612	heme a metabolic process
AltI4_43370	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AltI4_43380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AltI4_43390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AltI4_43420	COG0500	methyltransferase
AltI4_43450	COG3706	GGDEF domain
AltI4_43520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AltI4_43530	COG1414	Transcriptional regulator
AltI4_43540	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AltI4_43550	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_43580	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AltI4_43620	COG3254	rhamnose metabolic process
AltI4_43630	COG1874	Beta-galactosidase
AltI4_43700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AltI4_43710	COG0129	dihydroxy-acid dehydratase activity
AltI4_43720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AltI4_43730	COG0606	chelatase, subunit chli
AltI4_43740	COG0583	DNA-binding transcription factor activity
AltI4_43770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AltI4_43790	COG2814	Major facilitator Superfamily
AltI4_43800	COG3507	Belongs to the glycosyl hydrolase 43 family
AltI4_43830	COG2326	polyphosphate kinase activity
AltI4_43870	COG2911	Protein conserved in bacteria
AltI4_43910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AltI4_43930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AltI4_43940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AltI4_43980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AltI4_44040	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AltI4_44070	COG1228	amidohydrolase
AltI4_44110	COG0425	Belongs to the sulfur carrier protein TusA family
AltI4_44140	COG1561	YicC-like family, N-terminal region
AltI4_44160	COG3550	peptidyl-serine autophosphorylation
AltI4_44180	COG2153	protein acetylation
AltI4_44230	COG2211	Major facilitator Superfamily
AltI4_44240	COG1609	Transcriptional regulator
AltI4_44270	COG0840	transmembrane signaling receptor activity
AltI4_44300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AltI4_44300	COG2199	diguanylate cyclase activity
AltI4_44370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AltI4_44410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AltI4_44420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AltI4_44440	COG0356	it plays a direct role in the translocation of protons across the membrane
AltI4_44460	COG1475	DNA binding
AltI4_44470	COG1192	Involved in chromosome partitioning
AltI4_44520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AltI4_44550	COG0706	membrane insertase activity
AltI4_44570	COG0594	ribonuclease P activity
AltI4_44720	COG4771	TonB-dependent receptor
AltI4_44750	COG1960	acyl-CoA dehydrogenase activity
AltI4_44760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AltI4_44770	COG1024	Enoyl-CoA hydratase
AltI4_44790	COG0183	Belongs to the thiolase family
AltI4_44810	COG1024	Enoyl-CoA hydratase
AltI4_44820	COG1024	Enoyl-CoA hydratase
AltI4_44840	COG2814	Major facilitator Superfamily
AltI4_44860	COG0183	Belongs to the thiolase family
AltI4_44910	COG1472	Belongs to the glycosyl hydrolase 3 family
AltI4_44920	COG2211	Major facilitator Superfamily
AltI4_44950	COG2272	Belongs to the type-B carboxylesterase lipase family
AltI4_44960	COG2186	Transcriptional regulator
AltI4_44990	COG1960	acyl-CoA dehydrogenase activity
AltI4_45010	COG4206	TonB-dependent receptor
AltI4_45040	COG3507	Belongs to the glycosyl hydrolase 43 family
AltI4_45090	COG1192	Involved in chromosome partitioning
AltI4_45120	COG4206	TonB-dependent receptor
AltI4_45140	COG4771	TonB-dependent receptor
AltI4_45230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AltI4_45240	COG2971	BadF BadG BcrA BcrD
AltI4_45250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AltI4_45260	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AltI4_45300	COG0179	Fumarylacetoacetate (FAA) hydrolase
AltI4_45310	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_45330	COG1028	Short-chain dehydrogenase reductase Sdr
AltI4_45350	COG0129	dihydroxy-acid dehydratase activity
AltI4_45370	COG1250	3-hydroxyacyl-CoA dehydrogenase
AltI4_45370	COG1024	Enoyl-CoA hydratase