locus-tag	class	description
KUC14_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KUC14_00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KUC14_00040	COG0187	DNA topoisomerase II activity
KUC14_00100	COG2818	Glycosylase
KUC14_00120	COG3078	GTPase activator activity
KUC14_00160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KUC14_00160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KUC14_00170	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KUC14_00180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KUC14_00190	COG0569	domain protein
KUC14_00200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KUC14_00200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KUC14_00210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KUC14_00240	COG0758	DNA mediated transformation
KUC14_00270	COG0009	L-threonylcarbamoyladenylate synthase
KUC14_00280	COG0408	coproporphyrinogen oxidase activity
KUC14_00290	COG3047	cAMP biosynthetic process
KUC14_00320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KUC14_00420	COG2234	aminopeptidase activity
KUC14_00430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC14_00430	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KUC14_00460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KUC14_00510	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC14_00570	COG3642	lipopolysaccharide core region biosynthetic process
KUC14_00580	COG0859	PFAM glycosyl transferase family 9
KUC14_00640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KUC14_00670	COG3161	chorismate lyase activity
KUC14_00680	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KUC14_00720	COG0210	DNA helicase
KUC14_00750	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_00830	COG1595	DNA-templated transcription, initiation
KUC14_00840	COG0318	PFAM AMP-dependent synthetase and ligase
KUC14_00880	COG1024	Enoyl-CoA hydratase
KUC14_00890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC14_00910	COG1960	acyl-CoA dehydrogenase activity
KUC14_00930	COG4191	Histidine kinase
KUC14_00960	COG1136	(ABC) transporter
KUC14_00970	COG0577	efflux transmembrane transporter activity
KUC14_00980	COG3706	GGDEF domain
KUC14_00990	COG0745	RESPONSE REGULATOR receiver
KUC14_01000	COG2205	protein histidine kinase activity
KUC14_01020	COG0793	Belongs to the peptidase S41A family
KUC14_01040	COG4773	Receptor
KUC14_01060	COG1960	acyl-CoA dehydrogenase activity
KUC14_01070	COG0583	DNA-binding transcription factor activity
KUC14_01090	COG3106	COG3106 Predicted ATPase
KUC14_01130	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KUC14_01170	COG0352	thiamine-phosphate diphosphorylase activity
KUC14_01190	COG3071	HemY protein
KUC14_01200	COG2959	enzyme of heme biosynthesis
KUC14_01220	COG0181	hydroxymethylbilane synthase activity
KUC14_01250	COG0194	GDP metabolic process
KUC14_01270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUC14_01290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC14_01320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KUC14_01340	COG0678	peroxiredoxin activity
KUC14_01370	COG1178	ABC-type Fe3 transport system permease component
KUC14_01380	COG3842	ATPase activity
KUC14_01390	COG2081	HI0933 family
KUC14_01460	COG0583	DNA-binding transcription factor activity
KUC14_01500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC14_01530	COG0427	acetyl-CoA hydrolase
KUC14_01540	COG0123	including yeast histone deacetylase and acetoin utilization protein
KUC14_01570	COG0840	transmembrane signaling receptor activity
KUC14_01590	COG3064	Membrane
KUC14_01610	COG5002	protein histidine kinase activity
KUC14_01610	COG5001	Diguanylate cyclase
KUC14_01640	COG0514	ATP-dependent DNA helicase (RecQ)
KUC14_01650	COG2050	protein possibly involved in aromatic compounds catabolism
KUC14_01660	COG2239	Acts as a magnesium transporter
KUC14_01670	COG2962	Rard protein
KUC14_01690	COG0210	DNA helicase
KUC14_01720	COG1011	Hydrolase
KUC14_01730	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KUC14_01750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KUC14_01760	COG0019	diaminopimelate decarboxylase activity
KUC14_01810	COG0163	prenyltransferase activity
KUC14_01820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KUC14_01840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KUC14_01870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUC14_01920	COG1136	(ABC) transporter
KUC14_01920	COG0577	efflux transmembrane transporter activity
KUC14_01940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC14_01970	COG4555	ABC transporter
KUC14_02100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KUC14_02110	COG2814	Major facilitator Superfamily
KUC14_02120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KUC14_02170	COG1085	galactose-1-phosphate uridylyltransferase
KUC14_02180	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KUC14_02270	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC14_02320	COG1349	DNA-binding transcription factor activity
KUC14_02360	COG1077	Cell shape determining protein MreB Mrl
KUC14_02370	COG1792	Involved in formation and maintenance of cell shape
KUC14_02380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KUC14_02390	COG0424	maF-like protein
KUC14_02400	COG1530	ribonuclease E activity
KUC14_02420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC14_02430	COG0312	modulator of DNA gyrase
KUC14_02460	COG2205	protein histidine kinase activity
KUC14_02460	COG0784	Response regulator, receiver
KUC14_02470	COG3028	Belongs to the UPF0307 family
KUC14_02480	COG0312	modulator of DNA gyrase
KUC14_02490	COG2207	Transcriptional regulator
KUC14_02510	COG0745	RESPONSE REGULATOR receiver
KUC14_02520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC14_02520	COG4191	Histidine kinase
KUC14_02530	COG0297	glycogen (starch) synthase activity
KUC14_02550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KUC14_02600	COG0840	transmembrane signaling receptor activity
KUC14_02610	COG0745	RESPONSE REGULATOR receiver
KUC14_02620	COG2198	Histidine kinase
KUC14_02620	COG0643	Histidine kinase
KUC14_02630	COG0835	chemotaxis
KUC14_02710	COG1595	DNA-templated transcription, initiation
KUC14_02740	COG2205	protein histidine kinase activity
KUC14_02740	COG0784	Response regulator, receiver
KUC14_02800	COG2205	protein histidine kinase activity
KUC14_02800	COG0784	Response regulator, receiver
KUC14_02830	COG1609	Transcriptional regulator
KUC14_02840	COG0673	inositol 2-dehydrogenase activity
KUC14_02860	COG2211	Major facilitator Superfamily
KUC14_02870	COG1082	Xylose isomerase domain protein TIM barrel
KUC14_02910	COG1454	alcohol dehydrogenase
KUC14_02980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KUC14_03030	COG0089	rRNA binding
KUC14_03050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KUC14_03070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KUC14_03100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KUC14_03110	COG0297	glycogen (starch) synthase activity
KUC14_03130	COG1519	Transferase
KUC14_03170	COG0840	transmembrane signaling receptor activity
KUC14_03210	COG0788	formyltetrahydrofolate deformylase activity
KUC14_03230	COG1643	Atp-dependent helicase
KUC14_03240	COG2951	lytic endotransglycosylase activity
KUC14_03250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KUC14_03270	COG2354	Protein conserved in bacteria
KUC14_03320	COG0004	ammonium transporteR
KUC14_03330	COG0405	Gamma-glutamyltransferase
KUC14_03340	COG2837	iron assimilation
KUC14_03360	COG0540	Belongs to the ATCase OTCase family
KUC14_03380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC14_03410	COG0784	Response regulator, receiver
KUC14_03410	COG2205	protein histidine kinase activity
KUC14_03410	COG5002	protein histidine kinase activity
KUC14_03440	COG5001	Diguanylate cyclase
KUC14_03440	COG3300	MHYT domain
KUC14_03460	COG1012	belongs to the aldehyde dehydrogenase family
KUC14_03480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KUC14_03510	COG0180	Tryptophanyl-tRNA synthetase
KUC14_03520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KUC14_03560	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KUC14_03580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KUC14_03650	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KUC14_03660	COG0281	malic enzyme
KUC14_03680	COG0625	glutathione transferase activity
KUC14_03730	COG5001	Diguanylate cyclase
KUC14_03730	COG3300	MHYT domain
KUC14_03740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KUC14_03740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KUC14_03760	COG0137	argininosuccinate synthase activity
KUC14_03770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KUC14_03800	COG1803	Methylglyoxal synthase
KUC14_03820	COG0745	RESPONSE REGULATOR receiver
KUC14_03830	COG2205	protein histidine kinase activity
KUC14_03840	COG2267	carboxylic ester hydrolase activity
KUC14_03850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KUC14_03860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KUC14_03880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KUC14_03890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KUC14_03900	COG4942	peptidase
KUC14_03910	COG2861	carbohydrate metabolic process
KUC14_03930	COG0584	glycerophosphoryl diester phosphodiesterase
KUC14_03970	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KUC14_03990	COG0457	Tetratricopeptide repeat
KUC14_04020	COG0028	Belongs to the TPP enzyme family
KUC14_04040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC14_04050	COG1288	antiporter activity
KUC14_04060	COG4206	TonB-dependent receptor
KUC14_04100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KUC14_04110	COG0805	protein transport
KUC14_04130	COG0084	hydrolase, TatD family'
KUC14_04140	COG3706	GGDEF domain
KUC14_04140	COG2203	Gaf domain
KUC14_04140	COG4251	negative regulation of phosphorylation
KUC14_04140	COG5001	Diguanylate cyclase
KUC14_04160	COG0248	Ppx GppA phosphatase
KUC14_04170	COG0513	Belongs to the DEAD box helicase family
KUC14_04180	COG3118	belongs to the thioredoxin family
KUC14_04190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KUC14_04200	COG1473	amidohydrolase
KUC14_04210	COG0784	Response regulator, receiver
KUC14_04210	COG5002	protein histidine kinase activity
KUC14_04220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KUC14_04230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KUC14_04240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KUC14_04260	COG0783	Belongs to the Dps family
KUC14_04270	COG2133	pyrroloquinoline quinone binding
KUC14_04280	COG0823	Involved in the tonB-independent uptake of proteins
KUC14_04280	COG4946	Tricorn protease homolog
KUC14_04280	COG1506	peptidase
KUC14_04300	COG3118	belongs to the thioredoxin family
KUC14_04330	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KUC14_04350	COG1012	belongs to the aldehyde dehydrogenase family
KUC14_04400	COG1757	Na H antiporter
KUC14_04430	COG3876	Protein conserved in bacteria
KUC14_04440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KUC14_04480	COG0346	lactoylglutathione lyase activity
KUC14_04540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KUC14_04560	COG2824	Alkylphosphonate utilization operon protein PhnA
KUC14_04570	COG0454	-acetyltransferase
KUC14_04860	COG0183	Belongs to the thiolase family
KUC14_04870	COG1024	Enoyl-CoA hydratase
KUC14_04870	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUC14_04880	COG0739	heme binding
KUC14_04880	COG0741	lytic transglycosylase activity
KUC14_04880	COG1196	nuclear chromosome segregation
KUC14_04890	COG0006	proline dipeptidase activity
KUC14_04910	COG0142	geranyltranstransferase activity
KUC14_04960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KUC14_04970	COG1388	LysM domain
KUC14_04970	COG4942	peptidase
KUC14_04980	COG1238	metal cluster binding
KUC14_05000	COG0585	pseudouridine synthase activity
KUC14_05010	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KUC14_05030	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KUC14_05050	COG0840	transmembrane signaling receptor activity
KUC14_05060	COG1522	sequence-specific DNA binding
KUC14_05070	COG1063	alcohol dehydrogenase
KUC14_05090	COG4991	sh3 domain protein
KUC14_05130	COG0494	nUDIX hydrolase
KUC14_05140	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KUC14_05150	COG0730	response to heat
KUC14_05160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KUC14_05170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KUC14_05190	COG3706	GGDEF domain
KUC14_05200	COG3850	Histidine kinase
KUC14_05200	COG3437	response regulator, receiver
KUC14_05200	COG2205	protein histidine kinase activity
KUC14_05200	COG4999	Histidine kinase
KUC14_05210	COG2223	nitrite transmembrane transporter activity
KUC14_05240	COG0564	pseudouridine synthase activity
KUC14_05250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KUC14_05270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KUC14_05280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC14_05310	COG1648	precorrin-2 dehydrogenase activity
KUC14_05310	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KUC14_05320	COG0513	Belongs to the DEAD box helicase family
KUC14_05360	COG1538	Outer membrane efflux protein
KUC14_05370	COG0494	nUDIX hydrolase
KUC14_05400	COG3150	esterase
KUC14_05460	COG1509	lysine 2,3-aminomutase activity
KUC14_05470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KUC14_05480	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KUC14_05520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KUC14_05560	COG0271	Belongs to the BolA IbaG family
KUC14_05570	COG0671	phosphoesterase, PA-phosphatase related
KUC14_05590	COG3707	response regulator
KUC14_05610	COG0659	secondary active sulfate transmembrane transporter activity
KUC14_05620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUC14_05630	COG2146	nitrite reductase [NAD(P)H] activity
KUC14_05640	COG0243	molybdopterin cofactor binding
KUC14_05650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KUC14_05650	COG1648	precorrin-2 dehydrogenase activity
KUC14_05660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KUC14_05680	COG3706	GGDEF domain
KUC14_05700	COG1116	anion transmembrane transporter activity
KUC14_05700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KUC14_05720	COG1116	anion transmembrane transporter activity
KUC14_05740	COG0746	molybdenum cofactor guanylyltransferase activity
KUC14_05760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUC14_05770	COG4206	TonB-dependent receptor
KUC14_05780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KUC14_05790	COG0348	domain, Protein
KUC14_05820	COG1960	acyl-CoA dehydrogenase activity
KUC14_05830	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_05840	COG3618	amidohydrolase
KUC14_05850	COG4948	Mandelate Racemase Muconate Lactonizing
KUC14_05890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC14_05930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KUC14_05940	COG0358	DNA primase activity
KUC14_05990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KUC14_06000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KUC14_06030	COG0537	adenosine 5'-monophosphoramidase activity
KUC14_06060	COG3135	benzoate transporter
KUC14_06070	COG1396	sequence-specific DNA binding
KUC14_06080	COG2974	May be involved in recombination
KUC14_06090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC14_06090	COG4191	Histidine kinase
KUC14_06100	COG0745	RESPONSE REGULATOR receiver
KUC14_06110	COG5002	protein histidine kinase activity
KUC14_06170	COG0811	peptide transport
KUC14_06180	COG0811	peptide transport
KUC14_06190	COG0848	biopolymer transport protein
KUC14_06200	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KUC14_06220	COG3437	response regulator, receiver
KUC14_06230	COG0784	Response regulator, receiver
KUC14_06230	COG2205	protein histidine kinase activity
KUC14_06230	COG5002	protein histidine kinase activity
KUC14_06270	COG2133	pyrroloquinoline quinone binding
KUC14_06280	COG1049	propionate catabolic process, 2-methylcitrate cycle
KUC14_06300	COG3437	response regulator, receiver
KUC14_06300	COG3850	Histidine kinase
KUC14_06300	COG2205	protein histidine kinase activity
KUC14_06300	COG4999	Histidine kinase
KUC14_06310	COG2819	hydrolase of the alpha beta superfamily
KUC14_06340	COG1793	dna ligase
KUC14_06360	COG0527	aspartate kinase activity
KUC14_06370	COG5001	Diguanylate cyclase
KUC14_06370	COG3706	GGDEF domain
KUC14_06370	COG4251	negative regulation of phosphorylation
KUC14_06370	COG2203	Gaf domain
KUC14_06390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KUC14_06400	COG2967	ApaG domain
KUC14_06420	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KUC14_06430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC14_06440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KUC14_06450	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KUC14_06470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUC14_06480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KUC14_06510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KUC14_06540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUC14_06550	COG3956	TIGRFAM MazG family protein
KUC14_06610	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_06710	COG0642	Histidine kinase
KUC14_06750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KUC14_06760	COG0723	plastoquinol--plastocyanin reductase activity
KUC14_06770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KUC14_06780	COG2857	Cytochrome c1
KUC14_06790	COG0625	glutathione transferase activity
KUC14_06800	COG2969	positive regulation of protein catabolic process
KUC14_06830	COG0745	RESPONSE REGULATOR receiver
KUC14_06840	COG2239	Acts as a magnesium transporter
KUC14_06850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KUC14_06890	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KUC14_06900	COG1137	ATPase activity
KUC14_06910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KUC14_06930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KUC14_06960	COG1127	ABC transporter
KUC14_06970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KUC14_06980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KUC14_06990	COG2854	intermembrane phospholipid transfer
KUC14_07010	COG5007	Belongs to the BolA IbaG family
KUC14_07030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUC14_07040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUC14_07060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KUC14_07110	COG0583	DNA-binding transcription factor activity
KUC14_07120	COG0384	phenazine biosynthesis protein PhzF
KUC14_07130	COG0583	DNA-binding transcription factor activity
KUC14_07140	COG4977	sequence-specific DNA binding
KUC14_07140	COG1917	Cupin 2, conserved barrel domain protein
KUC14_07150	COG2259	Doxx family
KUC14_07180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KUC14_07200	COG3220	belongs to the UPF0276 family
KUC14_07270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC14_07310	COG1162	GTPase activity
KUC14_07380	COG0745	RESPONSE REGULATOR receiver
KUC14_07400	COG0697	spore germination
KUC14_07420	COG2205	protein histidine kinase activity
KUC14_07420	COG0784	Response regulator, receiver
KUC14_07490	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KUC14_07510	COG0126	phosphoglycerate kinase activity
KUC14_07520	COG3588	fructose-bisphosphate aldolase
KUC14_07560	COG0248	Ppx GppA phosphatase
KUC14_07570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KUC14_07590	COG0573	inorganic phosphate transmembrane transporter activity
KUC14_07610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KUC14_07630	COG0306	phosphate transporter
KUC14_07650	COG0583	DNA-binding transcription factor activity
KUC14_07700	COG1272	protein, Hemolysin III
KUC14_07710	COG1846	Transcriptional regulator
KUC14_07720	COG1764	response to oxidative stress
KUC14_07760	COG1739	Uncharacterized protein family UPF0029
KUC14_07790	COG0420	3'-5' exonuclease activity
KUC14_07800	COG0419	ATPase involved in DNA repair
KUC14_07830	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KUC14_07840	COG0010	Belongs to the arginase family
KUC14_07860	COG2188	Transcriptional regulator
KUC14_07870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KUC14_07880	COG2986	histidine ammonia-lyase
KUC14_07920	COG2971	BadF BadG BcrA BcrD
KUC14_07930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC14_07950	COG0488	(ABC) transporter
KUC14_07960	COG3002	Belongs to the UPF0753 family
KUC14_07970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KUC14_07980	COG0009	L-threonylcarbamoyladenylate synthase
KUC14_07990	COG0583	DNA-binding transcription factor activity
KUC14_08030	COG0668	transmembrane transport
KUC14_08060	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC14_08070	COG0583	DNA-binding transcription factor activity
KUC14_08090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KUC14_08130	COG1858	cytochrome C peroxidase
KUC14_08190	COG1346	cytolysis
KUC14_08260	COG0583	DNA-binding transcription factor activity
KUC14_08270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KUC14_08290	COG0513	Belongs to the DEAD box helicase family
KUC14_08320	COG3655	Transcriptional regulator
KUC14_08350	COG3267	Type II secretory pathway component ExeA
KUC14_08350	COG3409	Peptidoglycan-binding domain 1 protein
KUC14_08380	COG0066	3-isopropylmalate dehydratase activity
KUC14_08400	COG0473	3-isopropylmalate dehydrogenase activity
KUC14_08410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KUC14_08480	COG2271	Major facilitator Superfamily
KUC14_08500	COG0800	Aldolase
KUC14_08510	COG2186	Transcriptional regulator
KUC14_08580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KUC14_08610	COG4555	ABC transporter
KUC14_08620	COG1668	transmembrane transport
KUC14_08640	COG0745	RESPONSE REGULATOR receiver
KUC14_08710	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC14_08720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC14_08730	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC14_08750	COG1138	Cytochrome C-type biogenesis protein
KUC14_08790	COG2853	Lipoprotein
KUC14_08810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KUC14_08890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KUC14_08920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KUC14_08930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KUC14_08940	COG1555	photosystem II stabilization
KUC14_08950	COG0473	3-isopropylmalate dehydrogenase activity
KUC14_08980	COG1611	Belongs to the LOG family
KUC14_09080	COG0564	pseudouridine synthase activity
KUC14_09110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KUC14_09120	COG0024	Methionine aminopeptidase
KUC14_09130	COG0052	Belongs to the universal ribosomal protein uS2 family
KUC14_09150	COG0528	UMP kinase activity
KUC14_09170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KUC14_09180	COG0575	Belongs to the CDS family
KUC14_09190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KUC14_09200	COG0750	zinc metalloprotease
KUC14_09230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KUC14_09270	COG0587	DNA-directed DNA polymerase activity
KUC14_09280	COG0825	malonyl-CoA metabolic process
KUC14_09290	COG0037	tRNA processing
KUC14_09300	COG3706	GGDEF domain
KUC14_09360	COG0047	phosphoribosylformylglycinamidine synthase activity
KUC14_09360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KUC14_09380	COG2840	Smr protein MutS2
KUC14_09480	COG0784	Response regulator, receiver
KUC14_09480	COG0835	chemotaxis
KUC14_09490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KUC14_09500	COG1815	bacterial-type flagellum-dependent cell motility
KUC14_09520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KUC14_09530	COG1749	Flagellar hook protein flgE
KUC14_09540	COG4787	bacterial-type flagellum-dependent cell motility
KUC14_09580	COG3951	Flagellar rod assembly protein muramidase FlgJ
KUC14_09580	COG1705	Flagellar rod assembly protein muramidase FlgJ
KUC14_09590	COG1256	bacterial-type flagellum assembly
KUC14_09640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KUC14_09660	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KUC14_09730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KUC14_09740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KUC14_09780	COG1215	transferase activity, transferring glycosyl groups
KUC14_09790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KUC14_09800	COG1086	Polysaccharide biosynthesis protein
KUC14_09830	COG3475	LICD family
KUC14_09840	COG2089	acid synthase
KUC14_09860	COG1083	cytidylyl-transferase
KUC14_09870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC14_09920	COG1677	Flagellar hook-basal body complex protein FliE
KUC14_09930	COG1766	The M ring may be actively involved in energy transduction
KUC14_09940	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KUC14_10040	COG1987	bacterial-type flagellum assembly
KUC14_10070	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KUC14_10120	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KUC14_10130	COG0643	Histidine kinase
KUC14_10130	COG0784	Response regulator, receiver
KUC14_10130	COG2198	Histidine kinase
KUC14_10140	COG2201	protein-glutamate methylesterase activity
KUC14_10150	COG1192	Involved in chromosome partitioning
KUC14_10170	COG0835	chemotaxis
KUC14_10200	COG0646	methionine synthase
KUC14_10200	COG1410	methionine synthase
KUC14_10210	COG0646	methionine synthase
KUC14_10210	COG1410	methionine synthase
KUC14_10230	COG4269	membrane
KUC14_10260	COG0583	DNA-binding transcription factor activity
KUC14_10290	COG0659	secondary active sulfate transmembrane transporter activity
KUC14_10310	COG1309	transcriptional regulator
KUC14_10320	COG3590	peptidase
KUC14_10350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KUC14_10390	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KUC14_10400	COG4172	Belongs to the ABC transporter superfamily
KUC14_10420	COG4171	peptide transport system, permease
KUC14_10430	COG4168	peptide transport system, permease
KUC14_10440	COG0747	negative chemotaxis
KUC14_10450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KUC14_10460	COG1842	Phage shock protein A
KUC14_10530	COG0625	glutathione transferase activity
KUC14_10540	COG1522	sequence-specific DNA binding
KUC14_10640	COG0811	peptide transport
KUC14_10650	COG0811	peptide transport
KUC14_10660	COG0848	biopolymer transport protein
KUC14_10690	COG1444	tRNA N-acetyltransferase activity
KUC14_10760	COG0456	acetyltransferase
KUC14_10780	COG0583	DNA-binding transcription factor activity
KUC14_10790	COG2814	Major facilitator Superfamily
KUC14_10800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KUC14_10810	COG0656	L-ascorbic acid biosynthetic process
KUC14_10830	COG3706	GGDEF domain
KUC14_10870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC14_10880	COG3706	GGDEF domain
KUC14_10910	COG0583	DNA-binding transcription factor activity
KUC14_10920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KUC14_10950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KUC14_11000	COG0583	DNA-binding transcription factor activity
KUC14_11010	COG0702	epimerase
KUC14_11080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KUC14_11090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KUC14_11100	COG0564	pseudouridine synthase activity
KUC14_11120	COG0612	Peptidase, M16
KUC14_11130	COG2918	glutathione biosynthetic process
KUC14_11150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KUC14_11160	COG0784	Response regulator, receiver
KUC14_11160	COG5002	protein histidine kinase activity
KUC14_11180	COG1136	(ABC) transporter
KUC14_11190	COG1136	(ABC) transporter
KUC14_11190	COG0577	efflux transmembrane transporter activity
KUC14_11200	COG0577	efflux transmembrane transporter activity
KUC14_11200	COG1136	(ABC) transporter
KUC14_11230	COG0366	Alpha amylase catalytic
KUC14_11260	COG2840	Smr protein MutS2
KUC14_11270	COG2890	protein-(glutamine-N5) methyltransferase activity
KUC14_11300	COG2719	SpoVR family
KUC14_11310	COG2718	Belongs to the UPF0229 family
KUC14_11320	COG2766	serine protein kinase
KUC14_11330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KUC14_11340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KUC14_11350	COG4771	TonB-dependent receptor
KUC14_11380	COG4206	TonB-dependent receptor
KUC14_11400	COG0450	alkyl hydroperoxide reductase
KUC14_11430	COG2885	chlorophyll binding
KUC14_11440	COG0584	glycerophosphoryl diester phosphodiesterase
KUC14_11450	COG0346	lactoylglutathione lyase activity
KUC14_11460	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_11470	COG1278	Cold shock
KUC14_11500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KUC14_11510	COG4660	Part of a membrane complex involved in electron transport
KUC14_11520	COG4659	FMN binding
KUC14_11530	COG4658	electron transport chain
KUC14_11540	COG4656	Part of a membrane complex involved in electron transport
KUC14_11550	COG2878	Part of a membrane complex involved in electron transport
KUC14_11560	COG4657	Part of a membrane complex involved in electron transport
KUC14_11570	COG0534	Mate efflux family protein
KUC14_11580	COG0556	nucleotide-excision repair
KUC14_11630	COG0602	queuosine metabolic process
KUC14_11650	COG0367	asparagine synthase
KUC14_11700	COG3273	potassium ion transport
KUC14_11700	COG0471	metal ion transport
KUC14_11730	COG0529	Catalyzes the synthesis of activated sulfate
KUC14_11740	COG0175	sulfate reduction
KUC14_11750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC14_11810	COG2304	oxidoreductase activity
KUC14_11850	COG0714	Associated with various cellular activities
KUC14_11880	COG1024	Enoyl-CoA hydratase
KUC14_11880	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUC14_11920	COG1025	Belongs to the peptidase M16 family
KUC14_11930	COG2062	phosphohistidine phosphatase, SixA
KUC14_11950	COG4536	flavin adenine dinucleotide binding
KUC14_11960	COG4137	Cytochrome C assembly protein
KUC14_11970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KUC14_12050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC14_12060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC14_12070	COG1132	(ABC) transporter
KUC14_12080	COG0228	four-way junction DNA binding
KUC14_12090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KUC14_12100	COG0336	Belongs to the RNA methyltransferase TrmD family
KUC14_12110	COG0335	large ribosomal subunit rRNA binding
KUC14_12120	COG2860	membrane
KUC14_12150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KUC14_12160	COG0287	Prephenate dehydrogenase
KUC14_12160	COG1605	Chorismate mutase
KUC14_12180	COG1605	Chorismate mutase
KUC14_12180	COG0077	Prephenate dehydratase
KUC14_12190	COG0745	RESPONSE REGULATOR receiver
KUC14_12200	COG0023	Translation Initiation Factor
KUC14_12220	COG0745	RESPONSE REGULATOR receiver
KUC14_12260	COG2205	protein histidine kinase activity
KUC14_12280	COG2204	response regulator
KUC14_12300	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KUC14_12310	COG0494	nUDIX hydrolase
KUC14_12320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KUC14_12330	COG0632	four-way junction helicase activity
KUC14_12340	COG2255	four-way junction helicase activity
KUC14_12350	COG0824	Thioesterase
KUC14_12360	COG0811	peptide transport
KUC14_12390	COG0823	Involved in the tonB-independent uptake of proteins
KUC14_12400	COG2885	chlorophyll binding
KUC14_12410	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KUC14_12420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KUC14_12470	COG4319	ketosteroid isomerase
KUC14_12500	COG1725	Transcriptional regulator
KUC14_12610	COG3620	sequence-specific DNA binding
KUC14_12620	COG4667	esterase of the alpha-beta hydrolase superfamily
KUC14_12640	COG0513	Belongs to the DEAD box helicase family
KUC14_12680	COG0583	DNA-binding transcription factor activity
KUC14_12700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC14_12720	COG1309	transcriptional regulator
KUC14_12730	COG4774	siderophore transport
KUC14_12770	COG3706	GGDEF domain
KUC14_12790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KUC14_12790	COG3008	intermembrane lipid transfer
KUC14_12800	COG2995	paraquat-inducible protein a
KUC14_12820	COG0583	DNA-binding transcription factor activity
KUC14_12860	COG2207	Transcriptional regulator
KUC14_12870	COG0017	Asparaginyl-tRNA synthetase
KUC14_12900	COG0189	ligase activity
KUC14_12940	COG2201	protein-glutamate methylesterase activity
KUC14_12950	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KUC14_13010	COG0156	8-amino-7-oxononanoate synthase activity
KUC14_13040	COG3340	Belongs to the peptidase S51 family
KUC14_13050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KUC14_13060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KUC14_13070	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KUC14_13080	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KUC14_13140	COG2205	protein histidine kinase activity
KUC14_13150	COG0745	RESPONSE REGULATOR receiver
KUC14_13160	COG0569	domain protein
KUC14_13170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KUC14_13190	COG5265	(ABC) transporter
KUC14_13200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KUC14_13220	COG0745	RESPONSE REGULATOR receiver
KUC14_13230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUC14_13270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC14_13280	COG0402	S-adenosylhomocysteine deaminase activity
KUC14_13290	COG0402	S-adenosylhomocysteine deaminase activity
KUC14_13320	COG2755	lipolytic protein G-D-S-L family
KUC14_13330	COG4181	ATPase activity
KUC14_13340	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KUC14_13350	COG1090	epimerase
KUC14_13360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KUC14_13370	COG0628	permease
KUC14_13410	COG2350	Protein conserved in bacteria
KUC14_13420	COG0159	tryptophan synthase activity
KUC14_13440	COG0135	phosphoribosylanthranilate isomerase activity
KUC14_13440	COG0134	indole-3-glycerol-phosphate synthase activity
KUC14_13450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KUC14_13470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KUC14_13480	COG0613	PHP domain protein
KUC14_13490	COG0009	L-threonylcarbamoyladenylate synthase
KUC14_13510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KUC14_13540	COG0656	L-ascorbic acid biosynthetic process
KUC14_13550	COG2188	Transcriptional regulator
KUC14_13560	COG1131	(ABC) transporter
KUC14_13580	COG1506	peptidase
KUC14_13580	COG0823	Involved in the tonB-independent uptake of proteins
KUC14_13590	COG0110	maltose O-acetyltransferase activity
KUC14_13610	COG2733	membrane
KUC14_13640	COG0500	methyltransferase
KUC14_13650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC14_13660	COG0497	DNA recombination
KUC14_13670	COG0783	Belongs to the Dps family
KUC14_13680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KUC14_13700	COG1454	alcohol dehydrogenase
KUC14_13710	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_13730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KUC14_13740	COG2610	gluconate transmembrane transporter activity
KUC14_13770	COG2205	protein histidine kinase activity
KUC14_13770	COG0784	Response regulator, receiver
KUC14_13780	COG2199	diguanylate cyclase activity
KUC14_13790	COG2205	protein histidine kinase activity
KUC14_13790	COG0784	Response regulator, receiver
KUC14_13800	COG1620	l-lactate permease
KUC14_13810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KUC14_13830	COG0484	heat shock protein binding
KUC14_13840	COG3909	cytochrome
KUC14_13860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KUC14_13910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KUC14_13930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KUC14_13940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KUC14_13950	COG0840	transmembrane signaling receptor activity
KUC14_14010	COG0280	phosphate acetyltransferase
KUC14_14010	COG0857	belongs to the CobB CobQ family
KUC14_14020	COG1228	amidohydrolase
KUC14_14030	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KUC14_14040	COG4535	Mg2 and Co2 transporter CorC
KUC14_14060	COG1702	phosphate starvation-inducible protein PhoH
KUC14_14080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC14_14100	COG3706	GGDEF domain
KUC14_14110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC14_14120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC14_14210	COG1607	acyl-coa hydrolase
KUC14_14220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUC14_14230	COG1733	regulation of RNA biosynthetic process
KUC14_14240	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_14260	COG1115	amino acid carrier protein
KUC14_14280	COG0012	GTP binding
KUC14_14330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KUC14_14340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KUC14_14350	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KUC14_14360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KUC14_14380	COG2890	protein-(glutamine-N5) methyltransferase activity
KUC14_14390	COG3437	response regulator, receiver
KUC14_14390	COG0784	Response regulator, receiver
KUC14_14410	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KUC14_14430	COG0583	DNA-binding transcription factor activity
KUC14_14450	COG2363	Small membrane protein
KUC14_14490	COG3409	Peptidoglycan-binding domain 1 protein
KUC14_14490	COG0793	Belongs to the peptidase S41A family
KUC14_14500	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KUC14_14520	COG2116	formate transmembrane transporter activity
KUC14_14550	COG0714	Associated with various cellular activities
KUC14_14560	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KUC14_14570	COG0033	Phosphoglucomutase
KUC14_14580	COG0058	SHG alpha-glucan phosphorylase activity
KUC14_14590	COG3300	MHYT domain
KUC14_14590	COG5001	Diguanylate cyclase
KUC14_14600	COG2988	succinylglutamate desuccinylase activity
KUC14_14640	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KUC14_14680	COG1393	Belongs to the ArsC family
KUC14_14730	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KUC14_14760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KUC14_14790	COG3268	Saccharopine dehydrogenase
KUC14_14810	COG3300	MHYT domain
KUC14_14810	COG5001	Diguanylate cyclase
KUC14_14830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUC14_14850	COG1309	transcriptional regulator
KUC14_14950	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC14_15000	COG1733	regulation of RNA biosynthetic process
KUC14_15020	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC14_15030	COG3706	GGDEF domain
KUC14_15050	COG0402	S-adenosylhomocysteine deaminase activity
KUC14_15060	COG2351	hydroxyisourate hydrolase activity
KUC14_15090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KUC14_15110	COG1309	transcriptional regulator
KUC14_15140	COG2252	PERMEase
KUC14_15150	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KUC14_15190	COG2205	protein histidine kinase activity
KUC14_15190	COG0784	Response regulator, receiver
KUC14_15220	COG2233	PERMEase
KUC14_15250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KUC14_15260	COG0730	response to heat
KUC14_15280	COG0154	amidase activity
KUC14_15340	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_15350	COG3001	Fructosamine kinase
KUC14_15370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KUC14_15410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KUC14_15460	COG0489	protein tyrosine kinase activity
KUC14_15470	COG4464	protein tyrosine phosphatase activity
KUC14_15520	COG5001	Diguanylate cyclase
KUC14_15630	COG0463	Glycosyl transferase, family 2
KUC14_15660	COG0072	phenylalanine-tRNA ligase activity
KUC14_15660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC14_15720	COG1472	Belongs to the glycosyl hydrolase 3 family
KUC14_15740	COG2096	Adenosyltransferase
KUC14_15760	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KUC14_15780	COG4591	ABC-type transport system involved in lipoprotein release permease component
KUC14_15790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KUC14_15830	COG0708	Exodeoxyribonuclease III
KUC14_15940	COG2814	Major facilitator Superfamily
KUC14_16010	COG4770	biotin carboxylase activity
KUC14_16030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC14_16040	COG1960	acyl-CoA dehydrogenase activity
KUC14_16050	COG0789	Transcriptional regulator
KUC14_16060	COG0183	Belongs to the thiolase family
KUC14_16110	COG2925	Exonuclease
KUC14_16160	COG1643	Atp-dependent helicase
KUC14_16200	COG3321	synthase
KUC14_16200	COG0604	alcohol dehydrogenase
KUC14_16210	COG0328	RNA-DNA hybrid ribonuclease activity
KUC14_16220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KUC14_16240	COG1136	(ABC) transporter
KUC14_16250	COG4591	ABC-type transport system involved in lipoprotein release permease component
KUC14_16260	COG1301	dicarboxylic acid transport
KUC14_16280	COG3724	N-succinylarginine dihydrolase activity
KUC14_16300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KUC14_16310	COG3122	Protein conserved in bacteria
KUC14_16340	COG1609	Transcriptional regulator
KUC14_16380	COG0800	Aldolase
KUC14_16390	COG2271	Major facilitator Superfamily
KUC14_16400	COG4948	Mandelate Racemase Muconate Lactonizing
KUC14_16420	COG5285	phytanoyl-CoA dioxygenase
KUC14_16470	COG3119	arylsulfatase activity
KUC14_16600	COG2124	cytochrome p450
KUC14_16640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KUC14_16650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KUC14_16660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KUC14_16670	COG1012	belongs to the aldehyde dehydrogenase family
KUC14_16680	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_16690	COG1063	alcohol dehydrogenase
KUC14_16700	COG4948	Mandelate Racemase Muconate Lactonizing
KUC14_16720	COG3386	PFAM SMP-30 Gluconolaconase
KUC14_16730	COG2814	Major facilitator Superfamily
KUC14_16740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC14_16770	COG0625	glutathione transferase activity
KUC14_16800	COG0826	peptidase U32
KUC14_16810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KUC14_16820	COG2153	protein acetylation
KUC14_16880	COG5002	protein histidine kinase activity
KUC14_16900	COG1530	ribonuclease E activity
KUC14_16910	COG0564	pseudouridine synthase activity
KUC14_16920	COG0546	phosphoglycolate phosphatase activity
KUC14_16930	COG0424	maF-like protein
KUC14_16940	COG1399	metal-binding, possibly nucleic acid-binding protein
KUC14_16960	COG0416	fatty acid biosynthetic process
KUC14_16970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KUC14_16980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KUC14_17000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KUC14_17010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KUC14_17030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KUC14_17060	COG0084	hydrolase, TatD family'
KUC14_17070	COG0259	pyridoxamine-phosphate oxidase activity
KUC14_17080	COG0702	epimerase
KUC14_17130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KUC14_17140	COG1609	Transcriptional regulator
KUC14_17210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC14_17230	COG4771	TonB-dependent receptor
KUC14_17330	COG1238	metal cluster binding
KUC14_17370	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KUC14_17380	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KUC14_17390	COG0436	Aminotransferase
KUC14_17420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC14_17440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC14_17450	COG1765	OsmC-like protein
KUC14_17460	COG2996	Protein conserved in bacteria
KUC14_17480	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KUC14_17490	COG1984	allophanate hydrolase subunit 2
KUC14_17510	COG0735	belongs to the Fur family
KUC14_17530	COG0716	FMN binding
KUC14_17550	COG0596	Alpha beta hydrolase
KUC14_17660	COG1960	acyl-CoA dehydrogenase activity
KUC14_17670	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_17680	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_17690	COG1671	Belongs to the UPF0178 family
KUC14_17710	COG0840	transmembrane signaling receptor activity
KUC14_17730	COG1448	Aminotransferase
KUC14_17820	COG1024	Enoyl-CoA hydratase
KUC14_17830	COG0405	Gamma-glutamyltransferase
KUC14_18120	COG3547	Transposase (IS116 IS110 IS902 family)
KUC14_18130	COG3547	Transposase (IS116 IS110 IS902 family)
KUC14_18200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KUC14_18240	COG0534	Mate efflux family protein
KUC14_18250	COG0303	'Molybdopterin
KUC14_18270	COG0366	Alpha amylase catalytic
KUC14_18280	COG1215	transferase activity, transferring glycosyl groups
KUC14_18290	COG3769	mannosylglycerate metabolic process
KUC14_18300	COG0572	uridine kinase
KUC14_18360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KUC14_18430	COG1393	Belongs to the ArsC family
KUC14_18450	COG4783	chaperone-mediated protein folding
KUC14_18470	COG0583	DNA-binding transcription factor activity
KUC14_18500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KUC14_18530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUC14_18540	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KUC14_18600	COG3239	Fatty acid desaturase
KUC14_18620	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_18630	COG0583	DNA-binding transcription factor activity
KUC14_18650	COG0633	Ferredoxin
KUC14_18660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KUC14_18670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KUC14_18680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC14_18700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KUC14_18710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KUC14_18720	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KUC14_18730	COG0539	negative regulation of cytoplasmic translation
KUC14_18740	COG0776	regulation of translation
KUC14_18760	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KUC14_18770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KUC14_18780	COG0284	orotidine-5'-phosphate decarboxylase activity
KUC14_18790	COG0686	Belongs to the AlaDH PNT family
KUC14_18810	COG0531	amino acid
KUC14_18810	COG1674	ftsk spoiiie
KUC14_18820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KUC14_18830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KUC14_18920	COG2920	part of a sulfur-relay system
KUC14_18950	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KUC14_18960	COG0670	Belongs to the BI1 family
KUC14_19000	COG0583	DNA-binding transcription factor activity
KUC14_19010	COG2259	Doxx family
KUC14_19020	COG3384	dioxygenase
KUC14_19030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KUC14_19050	COG1741	Belongs to the pirin family
KUC14_19060	COG2197	response regulator
KUC14_19070	COG0322	excinuclease ABC activity
KUC14_19100	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KUC14_19110	COG3148	PFAM DTW domain containing protein
KUC14_19120	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KUC14_19130	COG2897	thiosulfate sulfurtransferase activity
KUC14_19150	COG1280	lysine exporter protein (LysE YggA)
KUC14_19190	COG1752	Esterase of the alpha-beta hydrolase superfamily
KUC14_19200	COG0037	tRNA processing
KUC14_19210	COG0589	response to stress
KUC14_19250	COG2217	Heavy metal translocating P-type atpase
KUC14_19270	COG2010	Cytochrome c
KUC14_19300	COG3278	Belongs to the heme-copper respiratory oxidase family
KUC14_19320	COG2193	ferroxidase activity
KUC14_19350	COG0069	glutamate synthase activity
KUC14_19370	COG0589	response to stress
KUC14_19380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KUC14_19400	COG4974	Belongs to the 'phage' integrase family
KUC14_19500	COG1082	Xylose isomerase domain protein TIM barrel
KUC14_19550	COG0534	Mate efflux family protein
KUC14_19570	COG3046	protein related to deoxyribodipyrimidine photolyase
KUC14_19580	COG0415	Belongs to the DNA photolyase family
KUC14_19590	COG0415	Belongs to the DNA photolyase family
KUC14_19600	COG0415	Belongs to the DNA photolyase family
KUC14_19620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KUC14_19630	COG3130	regulation of translation
KUC14_19650	COG0488	(ABC) transporter
KUC14_19680	COG0167	dihydroorotate dehydrogenase activity
KUC14_19690	COG2902	Dehydrogenase
KUC14_19750	COG0308	aminopeptidase N
KUC14_19760	COG1757	Na H antiporter
KUC14_19770	COG0733	neurotransmitter:sodium symporter activity
KUC14_19780	COG0793	Belongs to the peptidase S41A family
KUC14_19810	COG1956	GAF domain-containing protein
KUC14_19830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KUC14_19850	COG1946	Acyl-CoA thioesterase
KUC14_19870	COG0515	serine threonine protein kinase
KUC14_19880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KUC14_19900	COG0022	dehydrogenase e1 component
KUC14_19910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KUC14_19920	COG1404	Belongs to the peptidase S8 family
KUC14_19930	COG1322	Protein conserved in bacteria
KUC14_19960	COG0494	nUDIX hydrolase
KUC14_19970	COG1760	l-serine dehydratase
KUC14_20020	COG0583	DNA-binding transcription factor activity
KUC14_20030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KUC14_20040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KUC14_20050	COG0513	Belongs to the DEAD box helicase family
KUC14_20070	COG1054	Belongs to the UPF0176 family
KUC14_20100	COG2207	Transcriptional regulator
KUC14_20110	COG1073	alpha beta
KUC14_20130	COG0205	6-phosphofructokinase activity
KUC14_20150	COG3279	Response regulator of the LytR AlgR family
KUC14_20160	COG3275	phosphorelay sensor kinase activity
KUC14_20220	COG3081	Nucleoid-associated protein
KUC14_20230	COG3082	Protein of unknown function (DUF1414)
KUC14_20240	COG3083	sulfuric ester hydrolase activity
KUC14_20250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KUC14_20270	COG1024	Enoyl-CoA hydratase
KUC14_20280	COG1960	acyl-CoA dehydrogenase activity
KUC14_20300	COG2084	Dehydrogenase
KUC14_20310	COG0386	Belongs to the glutathione peroxidase family
KUC14_20320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KUC14_20330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC14_20340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KUC14_20370	COG0616	signal peptide processing
KUC14_20390	COG2267	carboxylic ester hydrolase activity
KUC14_20400	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_20420	COG1609	Transcriptional regulator
KUC14_20450	COG0366	Alpha amylase catalytic
KUC14_20500	COG4667	esterase of the alpha-beta hydrolase superfamily
KUC14_20610	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC14_20620	COG0567	Dehydrogenase, E1 component
KUC14_20630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KUC14_20640	COG1053	succinate dehydrogenase
KUC14_20650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KUC14_20670	COG0372	Belongs to the citrate synthase family
KUC14_20710	COG0435	Glutathione S-transferase
KUC14_20720	COG0579	oxidoreductase
KUC14_20730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KUC14_20810	COG1663	tetraacyldisaccharide 4'-kinase activity
KUC14_20820	COG1132	(ABC) transporter
KUC14_20830	COG2333	competence protein COMEC
KUC14_20830	COG0658	competence protein
KUC14_20850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KUC14_20870	COG1196	nuclear chromosome segregation
KUC14_20880	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KUC14_21060	COG2226	methyltransferase
KUC14_21280	COG1185	polyribonucleotide nucleotidyltransferase activity
KUC14_21310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KUC14_21320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KUC14_21330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC14_21360	COG0561	phosphatase activity
KUC14_21370	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_21390	COG1597	lipid kinase activity
KUC14_21390	COG1803	Methylglyoxal synthase
KUC14_21400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KUC14_21440	COG3706	GGDEF domain
KUC14_21450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KUC14_21460	COG0149	triose-phosphate isomerase activity
KUC14_21470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KUC14_21480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KUC14_21490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUC14_21500	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KUC14_21510	COG1534	Rna-binding protein
KUC14_21540	COG1067	ATP-dependent peptidase activity
KUC14_21560	COG0495	leucyl-tRNA aminoacylation
KUC14_21570	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
KUC14_21580	COG1466	dna polymerase III delta subunit
KUC14_21590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KUC14_21600	COG0799	negative regulation of ribosome biogenesis
KUC14_21610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KUC14_21620	COG0768	penicillin binding
KUC14_21630	COG0772	Belongs to the SEDS family
KUC14_21640	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KUC14_21650	COG1686	Belongs to the peptidase S11 family
KUC14_21660	COG2921	Belongs to the UPF0250 family
KUC14_21670	COG0321	lipoyl(octanoyl) transferase activity
KUC14_21680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KUC14_21690	COG0252	asparaginase activity
KUC14_21730	COG0778	Nitroreductase
KUC14_21760	COG0616	signal peptide processing
KUC14_21770	COG3092	negative regulation of chromosome organization
KUC14_21780	COG0492	ferredoxin-NADP+ reductase activity
KUC14_21790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KUC14_21800	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KUC14_21810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KUC14_21820	COG0542	response to heat
KUC14_21830	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KUC14_21840	COG1278	Cold shock
KUC14_21860	COG1187	pseudouridine synthase activity
KUC14_21870	COG0482	sulfurtransferase activity
KUC14_21880	COG2915	High frequency lysogenization protein hflD homolog
KUC14_21890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KUC14_21910	COG2850	peptidyl-arginine hydroxylation
KUC14_21980	COG0574	Belongs to the PEP-utilizing enzyme family
KUC14_21980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KUC14_22010	COG0457	Tetratricopeptide repeat
KUC14_22030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUC14_22050	COG2914	Belongs to the UPF0125 (RnfH) family
KUC14_22060	COG2867	negative regulation of translational initiation
KUC14_22080	COG1902	pentaerythritol trinitrate reductase activity
KUC14_22090	COG3706	GGDEF domain
KUC14_22110	COG1131	(ABC) transporter
KUC14_22170	COG0583	DNA-binding transcription factor activity
KUC14_22250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KUC14_22260	COG4136	ATPase activity
KUC14_22270	COG4135	transport system, permease component
KUC14_22280	COG4134	Bacterial extracellular solute-binding protein
KUC14_22300	COG4771	TonB-dependent receptor
KUC14_22330	COG1032	radical SAM domain protein
KUC14_22480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC14_22480	COG3153	acetyltransferase
KUC14_22540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KUC14_22570	COG0195	Participates in both transcription termination and antitermination
KUC14_22590	COG3437	response regulator, receiver
KUC14_22600	COG0784	Response regulator, receiver
KUC14_22600	COG2198	Histidine kinase
KUC14_22600	COG2205	protein histidine kinase activity
KUC14_22650	COG2205	protein histidine kinase activity
KUC14_22660	COG0745	RESPONSE REGULATOR receiver
KUC14_22680	COG4771	TonB-dependent receptor
KUC14_22690	COG0668	transmembrane transport
KUC14_22890	COG0596	Alpha beta hydrolase
KUC14_22900	COG1960	acyl-CoA dehydrogenase activity
KUC14_22910	COG0183	Belongs to the thiolase family
KUC14_22930	COG0596	Alpha beta hydrolase
KUC14_22940	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_22970	COG0366	Alpha amylase catalytic
KUC14_22980	COG0604	alcohol dehydrogenase
KUC14_23000	COG1960	acyl-CoA dehydrogenase activity
KUC14_23030	COG4771	TonB-dependent receptor
KUC14_23080	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KUC14_23120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KUC14_23130	COG0315	cyclic pyranopterin monophosphate synthase activity
KUC14_23140	COG0521	Mo-molybdopterin cofactor biosynthetic process
KUC14_23150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KUC14_23190	COG0436	Aminotransferase
KUC14_23200	COG3268	Saccharopine dehydrogenase
KUC14_23220	COG1017	nitric oxide dioxygenase activity
KUC14_23220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KUC14_23240	COG3604	Transcriptional regulator
KUC14_23290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC14_23320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KUC14_23330	COG1074	ATP-dependent DNA helicase activity
KUC14_23340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KUC14_23360	COG1022	Amp-dependent synthetase and ligase
KUC14_23370	COG5001	Diguanylate cyclase
KUC14_23370	COG3300	MHYT domain
KUC14_23400	COG0583	DNA-binding transcription factor activity
KUC14_23440	COG0640	Transcriptional regulator
KUC14_23460	COG0583	DNA-binding transcription factor activity
KUC14_23470	COG3932	Exopolysaccharide synthesis, ExoD
KUC14_23480	COG2204	response regulator
KUC14_23500	COG4251	negative regulation of phosphorylation
KUC14_23510	COG0784	Response regulator, receiver
KUC14_23520	COG2205	protein histidine kinase activity
KUC14_23520	COG0784	Response regulator, receiver
KUC14_23580	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KUC14_23630	COG3139	Protein of unknown function (DUF1315)
KUC14_23650	COG1115	amino acid carrier protein
KUC14_23660	COG2866	Carboxypeptidase
KUC14_23700	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KUC14_23720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KUC14_23730	COG1640	4-alpha-glucanotransferase
KUC14_23750	COG0676	glucose-6-phosphate 1-epimerase activity
KUC14_23760	COG0800	Aldolase
KUC14_23780	COG0129	dihydroxy-acid dehydratase activity
KUC14_23800	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KUC14_23810	COG1737	Transcriptional regulator
KUC14_23820	COG0469	pyruvate kinase activity
KUC14_23880	COG0784	Response regulator, receiver
KUC14_23880	COG2205	protein histidine kinase activity
KUC14_23910	COG2356	endonuclease I
KUC14_23970	COG0583	DNA-binding transcription factor activity
KUC14_23990	COG1979	alcohol dehydrogenase
KUC14_24000	COG5001	Diguanylate cyclase
KUC14_24020	COG0753	catalase activity
KUC14_24030	COG3437	response regulator, receiver
KUC14_24030	COG0784	Response regulator, receiver
KUC14_24040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC14_24040	COG4191	Histidine kinase
KUC14_24110	COG0778	Nitroreductase
KUC14_24150	COG0330	HflC and HflK could
KUC14_24210	COG0431	NADPH-dependent FMN reductase
KUC14_24220	COG1741	Belongs to the pirin family
KUC14_24230	COG0583	DNA-binding transcription factor activity
KUC14_24260	COG0471	metal ion transport
KUC14_24290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC14_24290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC14_24300	COG2226	methyltransferase
KUC14_24310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC14_24320	COG1388	LysM domain
KUC14_24320	COG0741	lytic transglycosylase activity
KUC14_24360	COG0215	cysteine-tRNA ligase activity
KUC14_24370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KUC14_24380	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUC14_24390	COG1785	Belongs to the alkaline phosphatase family
KUC14_24400	COG1785	Belongs to the alkaline phosphatase family
KUC14_24430	COG2268	Band 7 protein
KUC14_24450	COG1136	(ABC) transporter
KUC14_24490	COG2205	protein histidine kinase activity
KUC14_24550	COG0604	alcohol dehydrogenase
KUC14_24560	COG0583	DNA-binding transcription factor activity
KUC14_24630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KUC14_24640	COG1286	toxin biosynthetic process
KUC14_24650	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KUC14_24660	COG0285	dihydrofolate synthase activity
KUC14_24690	COG0101	tRNA pseudouridine synthase activity
KUC14_24720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KUC14_24750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KUC14_24770	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KUC14_24770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUC14_24810	COG1119	ATPase activity
KUC14_24830	COG0612	Peptidase, M16
KUC14_24850	COG2031	fatty acid transporter
KUC14_24880	COG3101	peptidyl-lysine hydroxylation
KUC14_24960	COG3119	arylsulfatase activity
KUC14_25040	COG4948	Mandelate Racemase Muconate Lactonizing
KUC14_25060	COG3119	arylsulfatase activity
KUC14_25070	COG3119	arylsulfatase activity
KUC14_25080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC14_25090	COG0800	Aldolase
KUC14_25110	COG2814	Major facilitator Superfamily
KUC14_25120	COG1609	Transcriptional regulator
KUC14_25160	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC14_25160	COG1902	pentaerythritol trinitrate reductase activity
KUC14_25210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KUC14_25230	COG4399	Belongs to the UPF0754 family
KUC14_25290	COG2186	Transcriptional regulator
KUC14_25310	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KUC14_25320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KUC14_25330	COG2983	Belongs to the UPF0260 family
KUC14_25340	COG0179	Fumarylacetoacetate (FAA) hydrolase
KUC14_25370	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KUC14_25380	COG0318	PFAM AMP-dependent synthetase and ligase
KUC14_25390	COG0318	PFAM AMP-dependent synthetase and ligase
KUC14_25400	COG2267	carboxylic ester hydrolase activity
KUC14_25430	COG1214	PFAM Peptidase M22, glycoprotease
KUC14_25440	COG1199	ATP-dependent helicase activity
KUC14_25470	COG0671	phosphoesterase, PA-phosphatase related
KUC14_25540	COG1192	Involved in chromosome partitioning
KUC14_25560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KUC14_25570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KUC14_25580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KUC14_25590	COG0131	Imidazoleglycerol-phosphate dehydratase
KUC14_25590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KUC14_25600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KUC14_25650	COG0583	DNA-binding transcription factor activity
KUC14_25660	COG0612	Peptidase, M16
KUC14_25670	COG0681	Belongs to the peptidase S26 family
KUC14_25710	COG0326	Molecular chaperone. Has ATPase activity
KUC14_25720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KUC14_25760	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KUC14_25770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KUC14_25790	COG3220	belongs to the UPF0276 family
KUC14_25820	COG1183	phosphatidylcholine synthase activity
KUC14_25850	COG0457	Tetratricopeptide repeat
KUC14_25860	COG0277	FAD linked oxidase domain protein
KUC14_25870	COG0542	response to heat
KUC14_25900	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC14_25920	COG1595	DNA-templated transcription, initiation
KUC14_25950	COG4221	oxidoreductase activity
KUC14_25960	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KUC14_25980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KUC14_26000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KUC14_26020	COG0142	geranyltranstransferase activity
KUC14_26040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KUC14_26050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KUC14_26070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KUC14_26100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUC14_26100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUC14_26130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUC14_26140	COG0488	(ABC) transporter
KUC14_26160	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KUC14_26180	COG0560	Phosphoserine phosphatase
KUC14_26200	COG0084	hydrolase, TatD family'
KUC14_26220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KUC14_26230	COG0571	ribonuclease III activity
KUC14_26270	COG3026	antisigma factor binding
KUC14_26290	COG1595	DNA-templated transcription, initiation
KUC14_26300	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KUC14_26330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KUC14_26350	COG1047	Peptidyl-prolyl cis-trans
KUC14_26490	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KUC14_26500	COG1047	Peptidyl-prolyl cis-trans
KUC14_26520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KUC14_26530	COG0196	riboflavin kinase activity
KUC14_26540	COG0728	peptidoglycan biosynthetic process
KUC14_26550	COG0268	Binds directly to 16S ribosomal RNA
KUC14_26580	COG1028	Short-chain dehydrogenase reductase Sdr
KUC14_26590	COG0385	Bile acid
KUC14_26650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC14_26660	COG0776	regulation of translation
KUC14_26670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KUC14_26690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KUC14_26700	COG0740	serine-type endopeptidase activity
KUC14_26710	COG0544	peptidyl-prolyl cis-trans isomerase activity
KUC14_26740	COG1720	tRNA m6t6A37 methyltransferase activity
KUC14_26760	COG1234	tRNA 3'-trailer cleavage
KUC14_26780	COG0123	including yeast histone deacetylase and acetoin utilization protein
KUC14_26810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KUC14_26840	COG1858	cytochrome C peroxidase
KUC14_26900	COG0516	GMP reductase activity
KUC14_26900	COG0517	IMP dehydrogenase activity
KUC14_26910	COG1570	exodeoxyribonuclease VII activity
KUC14_26960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC14_26970	COG2976	Protein conserved in bacteria
KUC14_27010	COG3063	Type IV pilus biogenesis stability protein PilW
KUC14_27020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KUC14_27040	COG2166	iron-sulfur cluster assembly
KUC14_27070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KUC14_27080	COG0719	Fe-S assembly protein
KUC14_27090	COG0396	ATPase activity
KUC14_27100	COG0719	Fe-S assembly protein
KUC14_27110	COG1104	cysteine desulfurase activity
KUC14_27120	COG1959	2 iron, 2 sulfur cluster binding
KUC14_27130	COG1045	serine acetyltransferase
KUC14_27140	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KUC14_27150	COG0483	inositol monophosphate 1-phosphatase activity
KUC14_27180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC14_27190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC14_27200	COG1862	Preprotein translocase
KUC14_27210	COG0343	queuine tRNA-ribosyltransferase activity
KUC14_27250	COG1842	Phage shock protein A
KUC14_27260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KUC14_27300	COG0754	glutathionylspermidine amidase activity
KUC14_27330	COG1136	(ABC) transporter
KUC14_27360	COG2066	Belongs to the glutaminase family
KUC14_27370	COG1785	Belongs to the alkaline phosphatase family
KUC14_27380	COG0745	RESPONSE REGULATOR receiver
KUC14_27550	COG0438	transferase activity, transferring glycosyl groups
KUC14_27640	COG0297	glycogen (starch) synthase activity
KUC14_27670	COG0367	asparagine synthase
KUC14_27730	COG0367	asparagine synthase
KUC14_27800	COG0489	protein tyrosine kinase activity
KUC14_27820	COG3409	Peptidoglycan-binding domain 1 protein
KUC14_27820	COG3267	Type II secretory pathway component ExeA
KUC14_27830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC14_27830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KUC14_27880	COG1560	Kdo2-lipid A biosynthetic process
KUC14_27910	COG1960	acyl-CoA dehydrogenase activity
KUC14_27940	COG1435	thymidine kinase activity
KUC14_27960	COG1609	Transcriptional regulator
KUC14_27970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KUC14_28010	COG1082	Xylose isomerase domain protein TIM barrel
KUC14_28030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC14_28060	COG1982	Orn Lys Arg decarboxylase major
KUC14_28090	COG1012	belongs to the aldehyde dehydrogenase family
KUC14_28130	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KUC14_28140	COG0789	Transcriptional regulator
KUC14_28210	COG1960	acyl-CoA dehydrogenase activity
KUC14_28340	COG4771	TonB-dependent receptor
KUC14_28370	COG1295	ribonuclease BN
KUC14_28410	COG3279	Response regulator of the LytR AlgR family
KUC14_28420	COG2819	hydrolase of the alpha beta superfamily
KUC14_28440	COG1917	Cupin 2, conserved barrel domain protein
KUC14_28440	COG4977	sequence-specific DNA binding
KUC14_28500	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC14_28700	COG4650	regulator
KUC14_28720	COG1690	Belongs to the RtcB family
KUC14_28730	COG0430	RNA-3'-phosphate cyclase activity
KUC14_28740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KUC14_28750	COG1690	Belongs to the RtcB family
KUC14_28770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KUC14_28770	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KUC14_28800	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KUC14_28860	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KUC14_28860	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KUC14_28900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KUC14_28920	COG0738	Major facilitator superfamily
KUC14_28930	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC14_28940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KUC14_28950	COG2971	BadF BadG BcrA BcrD
KUC14_28980	COG1609	Transcriptional regulator
KUC14_29000	COG0583	DNA-binding transcription factor activity
KUC14_29040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC14_29050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC14_29060	COG0006	proline dipeptidase activity
KUC14_29080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC14_29100	COG5002	protein histidine kinase activity
KUC14_29100	COG2198	Histidine kinase
KUC14_29100	COG0784	Response regulator, receiver
KUC14_29110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KUC14_29130	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KUC14_29140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KUC14_29180	COG3313	Fe-S protein
KUC14_29240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC14_29250	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC14_29260	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KUC14_29300	COG3577	Aspartyl protease
KUC14_29310	COG0157	Belongs to the NadC ModD family
KUC14_29330	COG1459	type II secretion system
KUC14_29340	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KUC14_29350	COG0237	dephospho-CoA kinase activity
KUC14_29360	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KUC14_29370	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KUC14_29390	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC14_29390	COG1902	pentaerythritol trinitrate reductase activity
KUC14_29400	COG2988	succinylglutamate desuccinylase activity
KUC14_29410	COG0494	nUDIX hydrolase
KUC14_29430	COG0739	heme binding
KUC14_29440	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KUC14_29450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KUC14_29460	COG0849	cell division
KUC14_29470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KUC14_29480	COG1181	Belongs to the D-alanine--D-alanine ligase family
KUC14_29490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KUC14_29510	COG0772	Belongs to the SEDS family
KUC14_29520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KUC14_29540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KUC14_29550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KUC14_29560	COG0768	penicillin binding
KUC14_29570	COG3116	cell division
KUC14_29590	COG2001	Belongs to the MraZ family
KUC14_29640	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC14_29690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KUC14_29690	COG0678	peroxiredoxin activity
KUC14_29740	COG2204	response regulator
KUC14_29820	COG0668	transmembrane transport
KUC14_29830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KUC14_29840	COG0189	ligase activity
KUC14_29850	COG1678	Uncharacterized ACR, COG1678
KUC14_29860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KUC14_29910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KUC14_29920	COG0762	integral membrane protein
KUC14_29980	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC14_29980	COG1902	pentaerythritol trinitrate reductase activity
KUC14_30020	COG0625	glutathione transferase activity
KUC14_30040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KUC14_30070	COG2378	regulation of single-species biofilm formation
KUC14_30120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KUC14_30140	COG0083	homoserine kinase activity
KUC14_30160	COG0583	DNA-binding transcription factor activity
KUC14_30180	COG2197	response regulator
KUC14_30190	COG4585	Histidine kinase
KUC14_30220	COG0840	transmembrane signaling receptor activity
KUC14_30230	COG0640	Transcriptional regulator
KUC14_30250	COG0431	NADPH-dependent FMN reductase
KUC14_30260	COG0798	PFAM Bile acid sodium symporter
KUC14_30270	COG2197	response regulator
KUC14_30280	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KUC14_30300	COG3850	Histidine kinase
KUC14_30300	COG5002	protein histidine kinase activity
KUC14_30350	COG1748	Saccharopine dehydrogenase
KUC14_30370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KUC14_30380	COG3107	peptidoglycan biosynthetic process
KUC14_30410	COG2823	Periplasmic or secreted lipoprotein
KUC14_30450	COG4585	Histidine kinase
KUC14_30460	COG2197	response regulator
KUC14_30490	COG1802	Transcriptional regulator
KUC14_30500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KUC14_30510	COG0372	Belongs to the citrate synthase family
KUC14_30520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KUC14_30540	COG2828	Protein conserved in bacteria
KUC14_30550	COG2203	Gaf domain
KUC14_30550	COG2199	diguanylate cyclase activity
KUC14_30580	COG0784	Response regulator, receiver
KUC14_30580	COG2198	Histidine kinase
KUC14_30580	COG5002	protein histidine kinase activity
KUC14_30590	COG3023	N-Acetylmuramoyl-L-alanine amidase
KUC14_30600	COG0067	glutamate synthase
KUC14_30600	COG0069	glutamate synthase activity
KUC14_30600	COG0070	glutamate synthase
KUC14_30610	COG0493	'glutamate synthase
KUC14_30620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KUC14_30660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KUC14_30670	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KUC14_30680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KUC14_30690	COG1054	Belongs to the UPF0176 family
KUC14_30720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUC14_30730	COG5507	3-demethylubiquinone-9 3-methyltransferase
KUC14_30740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KUC14_30750	COG1196	nuclear chromosome segregation
KUC14_30750	COG0739	heme binding
KUC14_30750	COG0741	lytic transglycosylase activity
KUC14_30760	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KUC14_30770	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KUC14_30820	COG0625	glutathione transferase activity
KUC14_30860	COG2326	polyphosphate kinase activity
KUC14_30890	COG1215	transferase activity, transferring glycosyl groups
KUC14_30920	COG2204	response regulator
KUC14_30950	COG2894	cell division
KUC14_30960	COG0850	regulation of cytokinetic process
KUC14_31000	COG1981	membrane
KUC14_31030	COG1914	H( )-stimulated, divalent metal cation uptake system
KUC14_31060	COG1217	gtp-binding protein TYPA
KUC14_31070	COG0174	glutamine synthetase
KUC14_31090	COG3852	Histidine kinase
KUC14_31120	COG3437	response regulator, receiver
KUC14_31190	COG0525	valine-tRNA ligase activity
KUC14_31200	COG2927	DNA polymerase III (CHI subunit)
KUC14_31210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KUC14_31220	COG0795	lipopolysaccharide-transporting ATPase activity
KUC14_31230	COG0795	lipopolysaccharide-transporting ATPase activity
KUC14_31250	COG0673	inositol 2-dehydrogenase activity
KUC14_31420	COG0464	growth
KUC14_31520	COG0328	RNA-DNA hybrid ribonuclease activity
KUC14_31520	COG3341	Caulimovirus viroplasmin
KUC14_31550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUC14_31600	COG0210	DNA helicase
KUC14_31840	COG0745	RESPONSE REGULATOR receiver
KUC14_31880	COG1024	Enoyl-CoA hydratase
KUC14_31930	COG1215	transferase activity, transferring glycosyl groups
KUC14_31940	COG0438	transferase activity, transferring glycosyl groups
KUC14_32080	COG0277	FAD linked oxidase domain protein
KUC14_32190	COG0513	Belongs to the DEAD box helicase family
KUC14_32250	COG2199	diguanylate cyclase activity
KUC14_32250	COG2200	EAL domain
KUC14_32250	COG2202	Pas domain
KUC14_32270	COG3568	Endonuclease Exonuclease Phosphatase
KUC14_32300	COG0730	response to heat
KUC14_32310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KUC14_32340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC14_32340	COG4191	Histidine kinase
KUC14_32360	COG0417	DNA replication proofreading
KUC14_32460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC14_32480	COG1573	uracil-dna glycosylase
KUC14_32490	COG3300	MHYT domain
KUC14_32490	COG5001	Diguanylate cyclase
KUC14_32530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KUC14_32570	COG1983	PspC domain protein
KUC14_32580	COG1842	Phage shock protein A
KUC14_32610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC14_32640	COG0542	response to heat
KUC14_32670	COG0204	Acyl-transferase
KUC14_32680	COG0204	Acyl-transferase
KUC14_32690	COG0668	transmembrane transport
KUC14_32720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KUC14_32730	COG0733	neurotransmitter:sodium symporter activity
KUC14_32760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KUC14_32810	COG0848	biopolymer transport protein
KUC14_32830	COG0457	Tetratricopeptide repeat
KUC14_32840	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KUC14_32890	COG0702	epimerase
KUC14_32930	COG5001	Diguanylate cyclase
KUC14_32930	COG5002	protein histidine kinase activity
KUC14_32950	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KUC14_32970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC14_32990	COG0583	DNA-binding transcription factor activity
KUC14_33000	COG0121	glutamine amidotransferase
KUC14_33020	COG4682	membrane
KUC14_33060	COG4628	conserved protein (DUF2132)
KUC14_33070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC14_33090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KUC14_33110	COG1477	protein flavinylation
KUC14_33120	COG2871	sodium ion transport
KUC14_33130	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC14_33140	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC14_33150	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC14_33160	COG1805	sodium ion transport
KUC14_33170	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC14_33180	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KUC14_33190	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC14_33200	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KUC14_33240	COG0039	L-malate dehydrogenase activity
KUC14_33250	COG1438	arginine binding
KUC14_33300	COG0572	uridine kinase
KUC14_33310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KUC14_33360	COG0517	IMP dehydrogenase activity
KUC14_33360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KUC14_33370	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC14_33390	COG2205	protein histidine kinase activity
KUC14_33390	COG0784	Response regulator, receiver
KUC14_33410	COG0189	ligase activity
KUC14_33430	COG0189	ligase activity
KUC14_33430	COG4067	protein conserved in archaea
KUC14_33460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KUC14_33480	COG1283	sodium-dependent phosphate transmembrane transporter activity
KUC14_33490	COG0667	Aldo Keto reductase
KUC14_33530	COG5001	Diguanylate cyclase
KUC14_33530	COG3300	MHYT domain
KUC14_33580	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KUC14_33600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KUC14_33610	COG0840	transmembrane signaling receptor activity
KUC14_33660	COG0583	DNA-binding transcription factor activity
KUC14_33690	COG0438	transferase activity, transferring glycosyl groups
KUC14_33690	COG1216	Glycosyl transferase, family 2
KUC14_33780	COG1216	Glycosyl transferase, family 2
KUC14_33780	COG1442	glycosyl transferase family 8
KUC14_33800	COG0463	Glycosyl transferase, family 2
KUC14_33900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KUC14_33910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KUC14_33960	COG0202	RNA polymerase activity
KUC14_34000	COG0201	protein transport
KUC14_34040	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KUC14_34110	COG2205	protein histidine kinase activity
KUC14_34110	COG0784	Response regulator, receiver
KUC14_34140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC14_34150	COG0557	exoribonuclease II activity
KUC14_34200	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KUC14_34300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KUC14_34320	COG4251	negative regulation of phosphorylation
KUC14_34360	COG3706	GGDEF domain
KUC14_34390	COG0456	acetyltransferase
KUC14_34390	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KUC14_34420	COG0583	DNA-binding transcription factor activity
KUC14_34460	COG1271	oxidase subunit
KUC14_34470	COG1294	oxidase, subunit
KUC14_34500	COG1522	sequence-specific DNA binding
KUC14_34520	COG1278	Cold shock
KUC14_34530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KUC14_34570	COG0339	signal peptide processing
KUC14_34580	COG2201	protein-glutamate methylesterase activity
KUC14_34600	COG4191	Histidine kinase
KUC14_34600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC14_34620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC14_34630	COG3437	response regulator, receiver
KUC14_34650	COG4946	Tricorn protease homolog
KUC14_34650	COG0823	Involved in the tonB-independent uptake of proteins
KUC14_34650	COG1506	peptidase
KUC14_34720	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KUC14_34730	COG1278	Cold shock
KUC14_34770	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KUC14_34780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KUC14_34810	COG0281	malic enzyme
KUC14_34830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KUC14_34890	COG0456	acetyltransferase
KUC14_34910	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KUC14_34920	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KUC14_34930	COG2177	Part of the ABC transporter FtsEX involved in
KUC14_34940	COG2884	Cell division ATP-binding protein ftsE
KUC14_34950	COG0552	protein localization to endoplasmic reticulum
KUC14_34960	COG0742	ribosomal rna small subunit methyltransferase
KUC14_34980	COG2095	MarC family integral membrane protein
KUC14_35020	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KUC14_35030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUC14_35050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KUC14_35080	COG0076	glutamate decarboxylase activity
KUC14_35110	COG0842	Transport permease protein
KUC14_35120	COG1131	(ABC) transporter
KUC14_35130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KUC14_35150	COG0745	RESPONSE REGULATOR receiver
KUC14_35160	COG2205	protein histidine kinase activity
KUC14_35170	COG4774	siderophore transport
KUC14_35220	COG1253	flavin adenine dinucleotide binding
KUC14_35230	COG0701	Predicted permease
KUC14_35240	COG1966	Carbon starvation protein
KUC14_35310	COG0848	biopolymer transport protein
KUC14_35350	COG0657	acetylesterase activity
KUC14_35380	COG1733	regulation of RNA biosynthetic process
KUC14_35400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KUC14_35410	COG0049	tRNA binding
KUC14_35420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KUC14_35430	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KUC14_35440	COG0085	RNA polymerase activity
KUC14_35450	COG0222	ribosome binding
KUC14_35460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KUC14_35470	COG0081	regulation of translation
KUC14_35480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KUC14_35510	COG0250	Participates in transcription elongation, termination and antitermination
KUC14_35520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KUC14_35530	COG1132	(ABC) transporter
KUC14_35550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KUC14_35560	COG3590	peptidase
KUC14_35590	COG0513	Belongs to the DEAD box helicase family
KUC14_35610	COG0418	dihydroorotase activity
KUC14_35620	COG3040	lipid binding
KUC14_35630	COG4989	oxidoreductase activity
KUC14_35640	COG0346	lactoylglutathione lyase activity
KUC14_35650	COG0668	transmembrane transport
KUC14_35690	COG0302	gtp cyclohydrolase
KUC14_35710	COG2957	Belongs to the agmatine deiminase family
KUC14_35720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC14_35740	COG1201	RNA secondary structure unwinding
KUC14_35760	COG1793	dna ligase
KUC14_35770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC14_35800	COG0583	DNA-binding transcription factor activity
KUC14_35820	COG0625	glutathione transferase activity
KUC14_35830	COG0625	glutathione transferase activity
KUC14_35850	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KUC14_35860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC14_35880	COG1012	belongs to the aldehyde dehydrogenase family
KUC14_35890	COG0028	Belongs to the TPP enzyme family
KUC14_35910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KUC14_35920	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KUC14_35930	COG0330	HflC and HflK could
KUC14_35940	COG0330	HflC and HflK could
KUC14_35950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KUC14_35960	COG1923	regulation of RNA biosynthetic process
KUC14_35970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KUC14_35980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KUC14_35990	COG0860	N-Acetylmuramoyl-L-alanine amidase
KUC14_36000	COG0802	atpase or kinase
KUC14_36010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KUC14_36010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KUC14_36020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KUC14_36050	COG2816	NAD+ diphosphatase activity
KUC14_36070	COG0735	belongs to the Fur family
KUC14_36110	COG0305	Participates in initiation and elongation during chromosome replication
KUC14_36160	COG2258	MOSC domain
KUC14_36260	COG0577	efflux transmembrane transporter activity
KUC14_36260	COG1136	(ABC) transporter
KUC14_36280	COG0840	transmembrane signaling receptor activity
KUC14_36290	COG5002	protein histidine kinase activity
KUC14_36300	COG0840	transmembrane signaling receptor activity
KUC14_36330	COG2855	membrane
KUC14_36350	COG0656	L-ascorbic acid biosynthetic process
KUC14_36390	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC14_36400	COG4771	TonB-dependent receptor
KUC14_36460	COG1472	Belongs to the glycosyl hydrolase 3 family
KUC14_36490	COG1609	Transcriptional regulator
KUC14_36500	COG0477	Major facilitator Superfamily
KUC14_36500	COG2814	Major facilitator Superfamily
KUC14_36510	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KUC14_36510	COG1618	nucleotide phosphatase activity, acting on free nucleotides
KUC14_36520	COG4988	ABC transporter
KUC14_36530	COG1294	oxidase, subunit
KUC14_36550	COG3829	transcription factor binding
KUC14_36600	COG4319	ketosteroid isomerase
KUC14_36610	COG1335	isochorismatase
KUC14_36630	COG0402	S-adenosylhomocysteine deaminase activity
KUC14_36640	COG1741	Belongs to the pirin family
KUC14_36660	COG4771	TonB-dependent receptor
KUC14_36690	COG1469	GTP cyclohydrolase I activity
KUC14_36770	COG0811	peptide transport
KUC14_36850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KUC14_36920	COG3706	GGDEF domain
KUC14_36920	COG4251	negative regulation of phosphorylation
KUC14_36920	COG5001	Diguanylate cyclase
KUC14_36920	COG2203	Gaf domain
KUC14_36930	COG1477	protein flavinylation
KUC14_37000	COG3237	CsbD-like
KUC14_37030	COG0596	Alpha beta hydrolase
KUC14_37030	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC14_37080	COG3038	cytochrome b561
KUC14_37090	COG2353	YceI-like domain
KUC14_37100	COG1252	NADH dehydrogenase
KUC14_37150	COG2067	long-chain fatty acid transport protein
KUC14_37160	COG2203	Gaf domain
KUC14_37160	COG3706	GGDEF domain
KUC14_37160	COG5001	Diguanylate cyclase
KUC14_37160	COG4251	negative regulation of phosphorylation
KUC14_37180	COG4191	Histidine kinase
KUC14_37190	COG2204	response regulator
KUC14_37200	COG0577	efflux transmembrane transporter activity
KUC14_37200	COG1136	(ABC) transporter
KUC14_37210	COG1136	(ABC) transporter
KUC14_37210	COG0577	efflux transmembrane transporter activity
KUC14_37230	COG5002	protein histidine kinase activity
KUC14_37230	COG5001	Diguanylate cyclase
KUC14_37250	COG0010	Belongs to the arginase family
KUC14_37260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KUC14_37280	COG0673	inositol 2-dehydrogenase activity
KUC14_37350	COG1166	arginine decarboxylase activity
KUC14_37370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KUC14_37530	COG5001	Diguanylate cyclase
KUC14_37540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC14_37550	COG1695	Transcriptional regulator
KUC14_37670	COG0328	RNA-DNA hybrid ribonuclease activity
KUC14_37720	COG3030	protein affecting phage T7 exclusion by the F plasmid
KUC14_37730	COG1324	tolerance protein
KUC14_37740	COG4232	protein-disulfide reductase activity
KUC14_37750	COG0739	heme binding
KUC14_37760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KUC14_37770	COG0511	ligase activity, forming carbon-carbon bonds
KUC14_37780	COG0439	Biotin carboxylase
KUC14_37880	COG0154	amidase activity
KUC14_37910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC14_37920	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KUC14_37950	COG0151	Belongs to the GarS family
KUC14_37970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KUC14_37980	COG3954	Phosphoribulokinase
KUC14_38040	COG1501	Belongs to the glycosyl hydrolase 31 family
KUC14_38060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KUC14_38070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KUC14_38090	COG3031	protein transport across the cell outer membrane
KUC14_38110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KUC14_38120	COG1459	type II secretion system
KUC14_38130	COG2165	general secretion pathway protein
KUC14_38140	COG2165	general secretion pathway protein
KUC14_38150	COG2165	general secretion pathway protein
KUC14_38160	COG4795	General secretion pathway protein
KUC14_38190	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KUC14_38230	COG1012	belongs to the aldehyde dehydrogenase family
KUC14_38250	COG1011	Hydrolase
KUC14_38260	COG0494	nUDIX hydrolase
KUC14_38270	COG1218	3'(2'),5'-bisphosphate nucleotidase
KUC14_38290	COG2943	transferase activity, transferring hexosyl groups
KUC14_38300	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KUC14_38320	COG3089	Belongs to the UPF0270 family
KUC14_38330	COG0429	hydrolase of the alpha beta-hydrolase fold
KUC14_38350	COG0488	(ABC) transporter
KUC14_38430	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC14_38450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KUC14_38460	COG2183	response to ionizing radiation
KUC14_38490	COG0596	Alpha beta hydrolase
KUC14_38500	COG1040	competence protein
KUC14_38530	COG1794	racemase activity, acting on amino acids and derivatives
KUC14_38560	COG0534	Mate efflux family protein
KUC14_38580	COG1649	PFAM Uncharacterised BCR, COG1649
KUC14_38580	COG0726	polysaccharide deacetylase
KUC14_38600	COG1999	signal sequence binding
KUC14_38610	COG0109	protoheme IX farnesyltransferase activity
KUC14_38620	COG1612	heme a metabolic process
KUC14_38670	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KUC14_38680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KUC14_38690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KUC14_38740	COG0129	dihydroxy-acid dehydratase activity
KUC14_38750	COG2860	membrane
KUC14_38760	COG0606	chelatase, subunit chli
KUC14_38770	COG0583	DNA-binding transcription factor activity
KUC14_38870	COG2814	Major facilitator Superfamily
KUC14_38880	COG1073	alpha beta
KUC14_38890	COG0729	surface antigen
KUC14_38900	COG2911	Protein conserved in bacteria
KUC14_38920	COG1595	DNA-templated transcription, initiation
KUC14_38950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KUC14_38970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KUC14_39010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KUC14_39060	COG1228	amidohydrolase
KUC14_39110	COG0425	Belongs to the sulfur carrier protein TusA family
KUC14_39140	COG1561	YicC-like family, N-terminal region
KUC14_39200	COG0270	DNA (cytosine-5-)-methyltransferase activity
KUC14_39300	COG2211	Major facilitator Superfamily
KUC14_39310	COG1609	Transcriptional regulator
KUC14_39340	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KUC14_39340	COG2199	diguanylate cyclase activity
KUC14_39350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KUC14_39390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KUC14_39430	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KUC14_39440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KUC14_39480	COG1475	DNA binding
KUC14_39490	COG1192	Involved in chromosome partitioning
KUC14_39520	COG0488	(ABC) transporter
KUC14_39550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KUC14_39560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KUC14_39630	COG0706	membrane insertase activity
KUC14_39640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KUC14_39650	COG0594	ribonuclease P activity