locus-tag	class	description
KUC3_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KUC3_00030	COG0187	DNA topoisomerase II activity
KUC3_00090	COG2818	Glycosylase
KUC3_00110	COG3078	GTPase activator activity
KUC3_00150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KUC3_00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KUC3_00160	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KUC3_00170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KUC3_00180	COG0569	domain protein
KUC3_00190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KUC3_00190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KUC3_00200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KUC3_00230	COG0758	DNA mediated transformation
KUC3_00260	COG0009	L-threonylcarbamoyladenylate synthase
KUC3_00270	COG0408	coproporphyrinogen oxidase activity
KUC3_00280	COG3047	cAMP biosynthetic process
KUC3_00310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KUC3_00410	COG2234	aminopeptidase activity
KUC3_00420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC3_00420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KUC3_00450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KUC3_00500	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_00560	COG3642	lipopolysaccharide core region biosynthetic process
KUC3_00570	COG0859	PFAM glycosyl transferase family 9
KUC3_00630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KUC3_00660	COG3161	chorismate lyase activity
KUC3_00670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KUC3_00710	COG0210	DNA helicase
KUC3_00740	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_00820	COG1595	DNA-templated transcription, initiation
KUC3_00830	COG0318	PFAM AMP-dependent synthetase and ligase
KUC3_00870	COG1024	Enoyl-CoA hydratase
KUC3_00880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC3_00900	COG1960	acyl-CoA dehydrogenase activity
KUC3_00920	COG4191	Histidine kinase
KUC3_00950	COG1136	(ABC) transporter
KUC3_00960	COG0577	efflux transmembrane transporter activity
KUC3_00970	COG3706	GGDEF domain
KUC3_00980	COG0745	RESPONSE REGULATOR receiver
KUC3_00990	COG2205	protein histidine kinase activity
KUC3_01010	COG0793	Belongs to the peptidase S41A family
KUC3_01030	COG4773	Receptor
KUC3_01050	COG1960	acyl-CoA dehydrogenase activity
KUC3_01060	COG0583	DNA-binding transcription factor activity
KUC3_01080	COG3106	COG3106 Predicted ATPase
KUC3_01120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KUC3_01160	COG0352	thiamine-phosphate diphosphorylase activity
KUC3_01180	COG3071	HemY protein
KUC3_01190	COG2959	enzyme of heme biosynthesis
KUC3_01210	COG0181	hydroxymethylbilane synthase activity
KUC3_01240	COG0194	GDP metabolic process
KUC3_01260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUC3_01280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC3_01310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KUC3_01330	COG0678	peroxiredoxin activity
KUC3_01360	COG1178	ABC-type Fe3 transport system permease component
KUC3_01370	COG3842	ATPase activity
KUC3_01380	COG2081	HI0933 family
KUC3_01430	COG3706	GGDEF domain
KUC3_01450	COG0583	DNA-binding transcription factor activity
KUC3_01490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_01520	COG0427	acetyl-CoA hydrolase
KUC3_01530	COG0123	including yeast histone deacetylase and acetoin utilization protein
KUC3_01560	COG0840	transmembrane signaling receptor activity
KUC3_01580	COG3064	Membrane
KUC3_01600	COG5002	protein histidine kinase activity
KUC3_01600	COG5001	Diguanylate cyclase
KUC3_01630	COG0514	ATP-dependent DNA helicase (RecQ)
KUC3_01640	COG2050	protein possibly involved in aromatic compounds catabolism
KUC3_01650	COG2239	Acts as a magnesium transporter
KUC3_01660	COG2962	Rard protein
KUC3_01680	COG0210	DNA helicase
KUC3_01710	COG1011	Hydrolase
KUC3_01720	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KUC3_01740	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KUC3_01750	COG0019	diaminopimelate decarboxylase activity
KUC3_01800	COG0163	prenyltransferase activity
KUC3_01810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KUC3_01830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KUC3_01860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUC3_01910	COG1136	(ABC) transporter
KUC3_01910	COG0577	efflux transmembrane transporter activity
KUC3_01930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_01960	COG4555	ABC transporter
KUC3_02090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KUC3_02100	COG2814	Major facilitator Superfamily
KUC3_02110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KUC3_02160	COG1085	galactose-1-phosphate uridylyltransferase
KUC3_02170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KUC3_02190	COG0629	single-stranded DNA binding
KUC3_02250	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_02300	COG1349	DNA-binding transcription factor activity
KUC3_02340	COG1077	Cell shape determining protein MreB Mrl
KUC3_02350	COG1792	Involved in formation and maintenance of cell shape
KUC3_02360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KUC3_02370	COG0424	maF-like protein
KUC3_02380	COG1530	ribonuclease E activity
KUC3_02400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC3_02410	COG0312	modulator of DNA gyrase
KUC3_02440	COG0784	Response regulator, receiver
KUC3_02440	COG2205	protein histidine kinase activity
KUC3_02450	COG3028	Belongs to the UPF0307 family
KUC3_02460	COG0312	modulator of DNA gyrase
KUC3_02470	COG2207	Transcriptional regulator
KUC3_02490	COG0745	RESPONSE REGULATOR receiver
KUC3_02500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_02500	COG4191	Histidine kinase
KUC3_02510	COG0297	glycogen (starch) synthase activity
KUC3_02530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KUC3_02580	COG0840	transmembrane signaling receptor activity
KUC3_02590	COG0745	RESPONSE REGULATOR receiver
KUC3_02600	COG2198	Histidine kinase
KUC3_02600	COG0643	Histidine kinase
KUC3_02610	COG0835	chemotaxis
KUC3_02690	COG1595	DNA-templated transcription, initiation
KUC3_02720	COG0784	Response regulator, receiver
KUC3_02720	COG2205	protein histidine kinase activity
KUC3_02780	COG0784	Response regulator, receiver
KUC3_02780	COG2205	protein histidine kinase activity
KUC3_02810	COG1609	Transcriptional regulator
KUC3_02820	COG0673	inositol 2-dehydrogenase activity
KUC3_02860	COG2211	Major facilitator Superfamily
KUC3_02870	COG2211	Major facilitator Superfamily
KUC3_02990	COG1454	alcohol dehydrogenase
KUC3_03080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KUC3_03130	COG0089	rRNA binding
KUC3_03150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KUC3_03170	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KUC3_03200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KUC3_03210	COG0297	glycogen (starch) synthase activity
KUC3_03230	COG1519	Transferase
KUC3_03270	COG0840	transmembrane signaling receptor activity
KUC3_03310	COG0788	formyltetrahydrofolate deformylase activity
KUC3_03330	COG1643	Atp-dependent helicase
KUC3_03340	COG2951	lytic endotransglycosylase activity
KUC3_03350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KUC3_03370	COG2354	Protein conserved in bacteria
KUC3_03420	COG0004	ammonium transporteR
KUC3_03430	COG0405	Gamma-glutamyltransferase
KUC3_03440	COG2837	iron assimilation
KUC3_03460	COG0540	Belongs to the ATCase OTCase family
KUC3_03480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_03510	COG2205	protein histidine kinase activity
KUC3_03510	COG5002	protein histidine kinase activity
KUC3_03510	COG0784	Response regulator, receiver
KUC3_03540	COG3300	MHYT domain
KUC3_03540	COG5001	Diguanylate cyclase
KUC3_03560	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_03580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KUC3_03610	COG0180	Tryptophanyl-tRNA synthetase
KUC3_03620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KUC3_03660	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KUC3_03680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KUC3_03750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KUC3_03760	COG0281	malic enzyme
KUC3_03780	COG0625	glutathione transferase activity
KUC3_03830	COG3300	MHYT domain
KUC3_03830	COG5001	Diguanylate cyclase
KUC3_03840	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KUC3_03840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KUC3_03860	COG0137	argininosuccinate synthase activity
KUC3_03870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KUC3_03900	COG1803	Methylglyoxal synthase
KUC3_03920	COG0745	RESPONSE REGULATOR receiver
KUC3_03930	COG2205	protein histidine kinase activity
KUC3_03940	COG2267	carboxylic ester hydrolase activity
KUC3_03950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KUC3_03960	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KUC3_03980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KUC3_03990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KUC3_04000	COG4942	peptidase
KUC3_04010	COG2861	carbohydrate metabolic process
KUC3_04030	COG0584	glycerophosphoryl diester phosphodiesterase
KUC3_04070	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KUC3_04090	COG0457	Tetratricopeptide repeat
KUC3_04120	COG0028	Belongs to the TPP enzyme family
KUC3_04140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC3_04150	COG1288	antiporter activity
KUC3_04160	COG4206	TonB-dependent receptor
KUC3_04200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KUC3_04210	COG0805	protein transport
KUC3_04230	COG0084	hydrolase, TatD family'
KUC3_04240	COG5001	Diguanylate cyclase
KUC3_04240	COG4251	negative regulation of phosphorylation
KUC3_04240	COG2203	Gaf domain
KUC3_04240	COG3706	GGDEF domain
KUC3_04260	COG0248	Ppx GppA phosphatase
KUC3_04270	COG0513	Belongs to the DEAD box helicase family
KUC3_04280	COG3118	belongs to the thioredoxin family
KUC3_04290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KUC3_04300	COG1473	amidohydrolase
KUC3_04310	COG0784	Response regulator, receiver
KUC3_04310	COG5002	protein histidine kinase activity
KUC3_04320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KUC3_04330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KUC3_04340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KUC3_04360	COG0783	Belongs to the Dps family
KUC3_04370	COG2133	pyrroloquinoline quinone binding
KUC3_04380	COG4946	Tricorn protease homolog
KUC3_04380	COG1506	peptidase
KUC3_04380	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_04400	COG3118	belongs to the thioredoxin family
KUC3_04430	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KUC3_04450	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_04500	COG1757	Na H antiporter
KUC3_04530	COG3876	Protein conserved in bacteria
KUC3_04540	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KUC3_04580	COG0346	lactoylglutathione lyase activity
KUC3_04640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KUC3_04660	COG2824	Alkylphosphonate utilization operon protein PhnA
KUC3_04670	COG0454	-acetyltransferase
KUC3_04960	COG3547	Transposase (IS116 IS110 IS902 family)
KUC3_05030	COG3547	Transposase (IS116 IS110 IS902 family)
KUC3_05100	COG3547	Transposase (IS116 IS110 IS902 family)
KUC3_05130	COG0183	Belongs to the thiolase family
KUC3_05140	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUC3_05140	COG1024	Enoyl-CoA hydratase
KUC3_05150	COG0739	heme binding
KUC3_05150	COG1196	nuclear chromosome segregation
KUC3_05150	COG0741	lytic transglycosylase activity
KUC3_05160	COG0006	proline dipeptidase activity
KUC3_05180	COG0142	geranyltranstransferase activity
KUC3_05230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KUC3_05240	COG4942	peptidase
KUC3_05240	COG1388	LysM domain
KUC3_05250	COG1238	metal cluster binding
KUC3_05270	COG0585	pseudouridine synthase activity
KUC3_05280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KUC3_05300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KUC3_05320	COG0840	transmembrane signaling receptor activity
KUC3_05330	COG1522	sequence-specific DNA binding
KUC3_05340	COG1063	alcohol dehydrogenase
KUC3_05360	COG4991	sh3 domain protein
KUC3_05400	COG0494	nUDIX hydrolase
KUC3_05410	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KUC3_05420	COG0730	response to heat
KUC3_05430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KUC3_05440	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KUC3_05460	COG3706	GGDEF domain
KUC3_05470	COG3850	Histidine kinase
KUC3_05470	COG3437	response regulator, receiver
KUC3_05470	COG4999	Histidine kinase
KUC3_05470	COG2205	protein histidine kinase activity
KUC3_05480	COG2223	nitrite transmembrane transporter activity
KUC3_05510	COG0564	pseudouridine synthase activity
KUC3_05520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KUC3_05540	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KUC3_05550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC3_05580	COG1648	precorrin-2 dehydrogenase activity
KUC3_05580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KUC3_05590	COG0513	Belongs to the DEAD box helicase family
KUC3_05630	COG1538	Outer membrane efflux protein
KUC3_05640	COG0494	nUDIX hydrolase
KUC3_05670	COG3150	esterase
KUC3_05730	COG1509	lysine 2,3-aminomutase activity
KUC3_05740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KUC3_05750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KUC3_05790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KUC3_05830	COG0271	Belongs to the BolA IbaG family
KUC3_05840	COG0671	phosphoesterase, PA-phosphatase related
KUC3_05860	COG3707	response regulator
KUC3_05880	COG0659	secondary active sulfate transmembrane transporter activity
KUC3_05890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUC3_05900	COG2146	nitrite reductase [NAD(P)H] activity
KUC3_05910	COG0243	molybdopterin cofactor binding
KUC3_05920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KUC3_05920	COG1648	precorrin-2 dehydrogenase activity
KUC3_05930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KUC3_05950	COG3706	GGDEF domain
KUC3_05970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KUC3_05970	COG1116	anion transmembrane transporter activity
KUC3_05990	COG1116	anion transmembrane transporter activity
KUC3_06010	COG0746	molybdenum cofactor guanylyltransferase activity
KUC3_06030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUC3_06040	COG4206	TonB-dependent receptor
KUC3_06050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KUC3_06060	COG0348	domain, Protein
KUC3_06090	COG1960	acyl-CoA dehydrogenase activity
KUC3_06100	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_06110	COG3618	amidohydrolase
KUC3_06120	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_06160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_06200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KUC3_06210	COG0358	DNA primase activity
KUC3_06260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KUC3_06270	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KUC3_06300	COG0537	adenosine 5'-monophosphoramidase activity
KUC3_06330	COG3135	benzoate transporter
KUC3_06340	COG1396	sequence-specific DNA binding
KUC3_06350	COG2974	May be involved in recombination
KUC3_06360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_06360	COG4191	Histidine kinase
KUC3_06370	COG0745	RESPONSE REGULATOR receiver
KUC3_06380	COG5002	protein histidine kinase activity
KUC3_06440	COG0811	peptide transport
KUC3_06450	COG0811	peptide transport
KUC3_06460	COG0848	biopolymer transport protein
KUC3_06470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KUC3_06490	COG3437	response regulator, receiver
KUC3_06500	COG5002	protein histidine kinase activity
KUC3_06500	COG2205	protein histidine kinase activity
KUC3_06500	COG0784	Response regulator, receiver
KUC3_06540	COG2133	pyrroloquinoline quinone binding
KUC3_06550	COG1049	propionate catabolic process, 2-methylcitrate cycle
KUC3_06570	COG2205	protein histidine kinase activity
KUC3_06570	COG3437	response regulator, receiver
KUC3_06570	COG3850	Histidine kinase
KUC3_06570	COG4999	Histidine kinase
KUC3_06580	COG2819	hydrolase of the alpha beta superfamily
KUC3_06610	COG1793	dna ligase
KUC3_06630	COG0527	aspartate kinase activity
KUC3_06640	COG2203	Gaf domain
KUC3_06640	COG3706	GGDEF domain
KUC3_06640	COG4251	negative regulation of phosphorylation
KUC3_06640	COG5001	Diguanylate cyclase
KUC3_06660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KUC3_06670	COG2967	ApaG domain
KUC3_06690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KUC3_06700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC3_06710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KUC3_06720	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KUC3_06740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUC3_06750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KUC3_06780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KUC3_06810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUC3_06820	COG3956	TIGRFAM MazG family protein
KUC3_06880	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_06980	COG0642	Histidine kinase
KUC3_07020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KUC3_07030	COG0723	plastoquinol--plastocyanin reductase activity
KUC3_07040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KUC3_07050	COG2857	Cytochrome c1
KUC3_07060	COG0625	glutathione transferase activity
KUC3_07070	COG2969	positive regulation of protein catabolic process
KUC3_07100	COG0745	RESPONSE REGULATOR receiver
KUC3_07110	COG2239	Acts as a magnesium transporter
KUC3_07120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KUC3_07160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KUC3_07170	COG1137	ATPase activity
KUC3_07180	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KUC3_07200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KUC3_07230	COG1127	ABC transporter
KUC3_07240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KUC3_07250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KUC3_07260	COG2854	intermembrane phospholipid transfer
KUC3_07280	COG5007	Belongs to the BolA IbaG family
KUC3_07300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUC3_07310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUC3_07330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KUC3_07380	COG0583	DNA-binding transcription factor activity
KUC3_07390	COG0384	phenazine biosynthesis protein PhzF
KUC3_07400	COG0583	DNA-binding transcription factor activity
KUC3_07410	COG4977	sequence-specific DNA binding
KUC3_07410	COG1917	Cupin 2, conserved barrel domain protein
KUC3_07420	COG2259	Doxx family
KUC3_07450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KUC3_07470	COG3220	belongs to the UPF0276 family
KUC3_07540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC3_07580	COG1162	GTPase activity
KUC3_07650	COG0745	RESPONSE REGULATOR receiver
KUC3_07670	COG0697	spore germination
KUC3_07690	COG0784	Response regulator, receiver
KUC3_07690	COG2205	protein histidine kinase activity
KUC3_07760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KUC3_07780	COG0126	phosphoglycerate kinase activity
KUC3_07790	COG3588	fructose-bisphosphate aldolase
KUC3_07830	COG0248	Ppx GppA phosphatase
KUC3_07840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KUC3_07860	COG0573	inorganic phosphate transmembrane transporter activity
KUC3_07880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KUC3_07900	COG0306	phosphate transporter
KUC3_07920	COG0583	DNA-binding transcription factor activity
KUC3_07970	COG1272	protein, Hemolysin III
KUC3_07980	COG1846	Transcriptional regulator
KUC3_07990	COG1764	response to oxidative stress
KUC3_08030	COG1739	Uncharacterized protein family UPF0029
KUC3_08060	COG0420	3'-5' exonuclease activity
KUC3_08070	COG0419	ATPase involved in DNA repair
KUC3_08100	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KUC3_08110	COG0010	Belongs to the arginase family
KUC3_08130	COG2188	Transcriptional regulator
KUC3_08140	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KUC3_08150	COG2986	histidine ammonia-lyase
KUC3_08190	COG2971	BadF BadG BcrA BcrD
KUC3_08200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC3_08220	COG0488	(ABC) transporter
KUC3_08230	COG3002	Belongs to the UPF0753 family
KUC3_08240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KUC3_08250	COG0009	L-threonylcarbamoyladenylate synthase
KUC3_08260	COG0583	DNA-binding transcription factor activity
KUC3_08300	COG0668	transmembrane transport
KUC3_08330	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC3_08340	COG0583	DNA-binding transcription factor activity
KUC3_08360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KUC3_08400	COG1858	cytochrome C peroxidase
KUC3_08460	COG1346	cytolysis
KUC3_08530	COG0583	DNA-binding transcription factor activity
KUC3_08540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KUC3_08560	COG0513	Belongs to the DEAD box helicase family
KUC3_08590	COG3655	Transcriptional regulator
KUC3_08620	COG3267	Type II secretory pathway component ExeA
KUC3_08620	COG3409	Peptidoglycan-binding domain 1 protein
KUC3_08650	COG0066	3-isopropylmalate dehydratase activity
KUC3_08670	COG0473	3-isopropylmalate dehydrogenase activity
KUC3_08680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KUC3_08750	COG2271	Major facilitator Superfamily
KUC3_08770	COG0800	Aldolase
KUC3_08780	COG2186	Transcriptional regulator
KUC3_08850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KUC3_08880	COG4555	ABC transporter
KUC3_08890	COG1668	transmembrane transport
KUC3_08910	COG0745	RESPONSE REGULATOR receiver
KUC3_08980	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC3_08990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC3_09000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KUC3_09020	COG1138	Cytochrome C-type biogenesis protein
KUC3_09060	COG2853	Lipoprotein
KUC3_09080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KUC3_09160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KUC3_09190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KUC3_09200	COG1555	photosystem II stabilization
KUC3_09210	COG0473	3-isopropylmalate dehydrogenase activity
KUC3_09240	COG1611	Belongs to the LOG family
KUC3_09340	COG0564	pseudouridine synthase activity
KUC3_09370	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KUC3_09380	COG0024	Methionine aminopeptidase
KUC3_09390	COG0052	Belongs to the universal ribosomal protein uS2 family
KUC3_09410	COG0528	UMP kinase activity
KUC3_09430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KUC3_09440	COG0575	Belongs to the CDS family
KUC3_09450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KUC3_09460	COG0750	zinc metalloprotease
KUC3_09490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KUC3_09530	COG0587	DNA-directed DNA polymerase activity
KUC3_09540	COG0825	malonyl-CoA metabolic process
KUC3_09550	COG0037	tRNA processing
KUC3_09560	COG3706	GGDEF domain
KUC3_09620	COG0047	phosphoribosylformylglycinamidine synthase activity
KUC3_09620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KUC3_09640	COG2840	Smr protein MutS2
KUC3_09750	COG0784	Response regulator, receiver
KUC3_09750	COG0835	chemotaxis
KUC3_09760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KUC3_09770	COG1815	bacterial-type flagellum-dependent cell motility
KUC3_09790	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KUC3_09800	COG1749	Flagellar hook protein flgE
KUC3_09810	COG4787	bacterial-type flagellum-dependent cell motility
KUC3_09850	COG3951	Flagellar rod assembly protein muramidase FlgJ
KUC3_09850	COG1705	Flagellar rod assembly protein muramidase FlgJ
KUC3_09860	COG1256	bacterial-type flagellum assembly
KUC3_09910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KUC3_09930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KUC3_10000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KUC3_10010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KUC3_10050	COG1215	transferase activity, transferring glycosyl groups
KUC3_10060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KUC3_10070	COG1086	Polysaccharide biosynthesis protein
KUC3_10100	COG3475	LICD family
KUC3_10110	COG2089	acid synthase
KUC3_10130	COG1083	cytidylyl-transferase
KUC3_10140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC3_10190	COG1677	Flagellar hook-basal body complex protein FliE
KUC3_10200	COG1766	The M ring may be actively involved in energy transduction
KUC3_10210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KUC3_10310	COG1987	bacterial-type flagellum assembly
KUC3_10340	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KUC3_10390	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KUC3_10400	COG0643	Histidine kinase
KUC3_10400	COG2198	Histidine kinase
KUC3_10400	COG0784	Response regulator, receiver
KUC3_10410	COG2201	protein-glutamate methylesterase activity
KUC3_10420	COG1192	Involved in chromosome partitioning
KUC3_10440	COG0835	chemotaxis
KUC3_10470	COG0646	methionine synthase
KUC3_10470	COG1410	methionine synthase
KUC3_10480	COG1410	methionine synthase
KUC3_10480	COG0646	methionine synthase
KUC3_10500	COG4269	membrane
KUC3_10530	COG0583	DNA-binding transcription factor activity
KUC3_10560	COG0659	secondary active sulfate transmembrane transporter activity
KUC3_10590	COG1309	transcriptional regulator
KUC3_10600	COG3590	peptidase
KUC3_10630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KUC3_10670	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KUC3_10680	COG4172	Belongs to the ABC transporter superfamily
KUC3_10700	COG4171	peptide transport system, permease
KUC3_10710	COG4168	peptide transport system, permease
KUC3_10720	COG0747	negative chemotaxis
KUC3_10730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KUC3_10740	COG1842	Phage shock protein A
KUC3_10810	COG0625	glutathione transferase activity
KUC3_10820	COG1522	sequence-specific DNA binding
KUC3_10920	COG0811	peptide transport
KUC3_10930	COG0811	peptide transport
KUC3_10940	COG0848	biopolymer transport protein
KUC3_10970	COG1444	tRNA N-acetyltransferase activity
KUC3_11040	COG0456	acetyltransferase
KUC3_11060	COG0583	DNA-binding transcription factor activity
KUC3_11070	COG2814	Major facilitator Superfamily
KUC3_11080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KUC3_11090	COG0656	L-ascorbic acid biosynthetic process
KUC3_11110	COG3706	GGDEF domain
KUC3_11150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC3_11160	COG3706	GGDEF domain
KUC3_11190	COG0583	DNA-binding transcription factor activity
KUC3_11200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KUC3_11230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KUC3_11280	COG0583	DNA-binding transcription factor activity
KUC3_11290	COG0702	epimerase
KUC3_11360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KUC3_11370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KUC3_11380	COG0564	pseudouridine synthase activity
KUC3_11400	COG0612	Peptidase, M16
KUC3_11410	COG2918	glutathione biosynthetic process
KUC3_11430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KUC3_11440	COG0784	Response regulator, receiver
KUC3_11440	COG5002	protein histidine kinase activity
KUC3_11460	COG1136	(ABC) transporter
KUC3_11470	COG1136	(ABC) transporter
KUC3_11470	COG0577	efflux transmembrane transporter activity
KUC3_11480	COG0577	efflux transmembrane transporter activity
KUC3_11480	COG1136	(ABC) transporter
KUC3_11510	COG0366	Alpha amylase catalytic
KUC3_11540	COG2840	Smr protein MutS2
KUC3_11550	COG2890	protein-(glutamine-N5) methyltransferase activity
KUC3_11580	COG2719	SpoVR family
KUC3_11590	COG2718	Belongs to the UPF0229 family
KUC3_11600	COG2766	serine protein kinase
KUC3_11610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KUC3_11620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KUC3_11630	COG4771	TonB-dependent receptor
KUC3_11660	COG4206	TonB-dependent receptor
KUC3_11680	COG0450	alkyl hydroperoxide reductase
KUC3_11710	COG2885	chlorophyll binding
KUC3_11720	COG0584	glycerophosphoryl diester phosphodiesterase
KUC3_11730	COG0346	lactoylglutathione lyase activity
KUC3_11740	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_11750	COG1278	Cold shock
KUC3_11780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KUC3_11790	COG4660	Part of a membrane complex involved in electron transport
KUC3_11800	COG4659	FMN binding
KUC3_11810	COG4658	electron transport chain
KUC3_11820	COG4656	Part of a membrane complex involved in electron transport
KUC3_11830	COG2878	Part of a membrane complex involved in electron transport
KUC3_11840	COG4657	Part of a membrane complex involved in electron transport
KUC3_11850	COG0534	Mate efflux family protein
KUC3_11860	COG0556	nucleotide-excision repair
KUC3_11910	COG0602	queuosine metabolic process
KUC3_11930	COG0367	asparagine synthase
KUC3_11980	COG0471	metal ion transport
KUC3_11980	COG3273	potassium ion transport
KUC3_12010	COG0529	Catalyzes the synthesis of activated sulfate
KUC3_12020	COG0175	sulfate reduction
KUC3_12030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_12090	COG2304	oxidoreductase activity
KUC3_12130	COG0714	Associated with various cellular activities
KUC3_12150	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUC3_12150	COG1024	Enoyl-CoA hydratase
KUC3_12180	COG1025	Belongs to the peptidase M16 family
KUC3_12190	COG2062	phosphohistidine phosphatase, SixA
KUC3_12210	COG4536	flavin adenine dinucleotide binding
KUC3_12220	COG4137	Cytochrome C assembly protein
KUC3_12230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KUC3_12310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_12320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_12330	COG1132	(ABC) transporter
KUC3_12340	COG0228	four-way junction DNA binding
KUC3_12350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KUC3_12360	COG0336	Belongs to the RNA methyltransferase TrmD family
KUC3_12370	COG0335	large ribosomal subunit rRNA binding
KUC3_12380	COG2860	membrane
KUC3_12410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KUC3_12420	COG0287	Prephenate dehydrogenase
KUC3_12420	COG1605	Chorismate mutase
KUC3_12440	COG1605	Chorismate mutase
KUC3_12440	COG0077	Prephenate dehydratase
KUC3_12450	COG0745	RESPONSE REGULATOR receiver
KUC3_12460	COG0023	Translation Initiation Factor
KUC3_12480	COG0745	RESPONSE REGULATOR receiver
KUC3_12530	COG2205	protein histidine kinase activity
KUC3_12550	COG2204	response regulator
KUC3_12570	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KUC3_12580	COG0494	nUDIX hydrolase
KUC3_12590	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KUC3_12600	COG0632	four-way junction helicase activity
KUC3_12610	COG2255	four-way junction helicase activity
KUC3_12620	COG0824	Thioesterase
KUC3_12630	COG0811	peptide transport
KUC3_12660	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_12670	COG2885	chlorophyll binding
KUC3_12680	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KUC3_12690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KUC3_12740	COG4319	ketosteroid isomerase
KUC3_12770	COG1725	Transcriptional regulator
KUC3_12880	COG3620	sequence-specific DNA binding
KUC3_12890	COG4667	esterase of the alpha-beta hydrolase superfamily
KUC3_12910	COG0513	Belongs to the DEAD box helicase family
KUC3_12950	COG0583	DNA-binding transcription factor activity
KUC3_12970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_12990	COG1309	transcriptional regulator
KUC3_13000	COG4774	siderophore transport
KUC3_13040	COG3706	GGDEF domain
KUC3_13060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KUC3_13060	COG3008	intermembrane lipid transfer
KUC3_13070	COG2995	paraquat-inducible protein a
KUC3_13090	COG0583	DNA-binding transcription factor activity
KUC3_13130	COG2207	Transcriptional regulator
KUC3_13140	COG0017	Asparaginyl-tRNA synthetase
KUC3_13170	COG0189	ligase activity
KUC3_13210	COG2201	protein-glutamate methylesterase activity
KUC3_13220	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KUC3_13280	COG0156	8-amino-7-oxononanoate synthase activity
KUC3_13310	COG3340	Belongs to the peptidase S51 family
KUC3_13320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KUC3_13330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KUC3_13340	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KUC3_13350	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KUC3_13410	COG2205	protein histidine kinase activity
KUC3_13420	COG0745	RESPONSE REGULATOR receiver
KUC3_13430	COG0569	domain protein
KUC3_13440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KUC3_13460	COG5265	(ABC) transporter
KUC3_13470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KUC3_13490	COG0745	RESPONSE REGULATOR receiver
KUC3_13500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUC3_13540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC3_13550	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_13560	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_13590	COG2755	lipolytic protein G-D-S-L family
KUC3_13600	COG4181	ATPase activity
KUC3_13610	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KUC3_13620	COG1090	epimerase
KUC3_13630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KUC3_13640	COG0628	permease
KUC3_13680	COG2350	Protein conserved in bacteria
KUC3_13690	COG0159	tryptophan synthase activity
KUC3_13710	COG0135	phosphoribosylanthranilate isomerase activity
KUC3_13710	COG0134	indole-3-glycerol-phosphate synthase activity
KUC3_13720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KUC3_13740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KUC3_13750	COG0613	PHP domain protein
KUC3_13760	COG0009	L-threonylcarbamoyladenylate synthase
KUC3_13780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KUC3_13810	COG0656	L-ascorbic acid biosynthetic process
KUC3_13820	COG2188	Transcriptional regulator
KUC3_13830	COG1131	(ABC) transporter
KUC3_13850	COG1506	peptidase
KUC3_13850	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_13860	COG0110	maltose O-acetyltransferase activity
KUC3_13880	COG2733	membrane
KUC3_13910	COG0500	methyltransferase
KUC3_13920	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_13930	COG0497	DNA recombination
KUC3_13940	COG0783	Belongs to the Dps family
KUC3_13950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KUC3_13970	COG1454	alcohol dehydrogenase
KUC3_13980	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_14000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KUC3_14010	COG2610	gluconate transmembrane transporter activity
KUC3_14040	COG0784	Response regulator, receiver
KUC3_14040	COG2205	protein histidine kinase activity
KUC3_14050	COG2199	diguanylate cyclase activity
KUC3_14060	COG0784	Response regulator, receiver
KUC3_14060	COG2205	protein histidine kinase activity
KUC3_14070	COG1620	l-lactate permease
KUC3_14080	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KUC3_14100	COG0484	heat shock protein binding
KUC3_14110	COG3909	cytochrome
KUC3_14130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KUC3_14180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KUC3_14200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KUC3_14210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KUC3_14220	COG0840	transmembrane signaling receptor activity
KUC3_14280	COG0857	belongs to the CobB CobQ family
KUC3_14280	COG0280	phosphate acetyltransferase
KUC3_14290	COG1228	amidohydrolase
KUC3_14300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KUC3_14310	COG4535	Mg2 and Co2 transporter CorC
KUC3_14330	COG1702	phosphate starvation-inducible protein PhoH
KUC3_14350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC3_14370	COG3706	GGDEF domain
KUC3_14380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_14390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_14480	COG1607	acyl-coa hydrolase
KUC3_14490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUC3_14500	COG1733	regulation of RNA biosynthetic process
KUC3_14510	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_14530	COG1115	amino acid carrier protein
KUC3_14550	COG0012	GTP binding
KUC3_14600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KUC3_14610	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KUC3_14620	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KUC3_14630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KUC3_14650	COG2890	protein-(glutamine-N5) methyltransferase activity
KUC3_14660	COG3437	response regulator, receiver
KUC3_14660	COG0784	Response regulator, receiver
KUC3_14680	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KUC3_14700	COG0583	DNA-binding transcription factor activity
KUC3_14720	COG2363	Small membrane protein
KUC3_14760	COG0793	Belongs to the peptidase S41A family
KUC3_14760	COG3409	Peptidoglycan-binding domain 1 protein
KUC3_14770	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KUC3_14790	COG2116	formate transmembrane transporter activity
KUC3_14820	COG0714	Associated with various cellular activities
KUC3_14830	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KUC3_14840	COG0033	Phosphoglucomutase
KUC3_14850	COG0058	SHG alpha-glucan phosphorylase activity
KUC3_14860	COG5001	Diguanylate cyclase
KUC3_14860	COG3300	MHYT domain
KUC3_14870	COG2988	succinylglutamate desuccinylase activity
KUC3_14910	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KUC3_14950	COG1393	Belongs to the ArsC family
KUC3_15000	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KUC3_15030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KUC3_15060	COG3268	Saccharopine dehydrogenase
KUC3_15080	COG3300	MHYT domain
KUC3_15080	COG5001	Diguanylate cyclase
KUC3_15100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUC3_15120	COG1309	transcriptional regulator
KUC3_15220	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC3_15270	COG1733	regulation of RNA biosynthetic process
KUC3_15290	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUC3_15300	COG3706	GGDEF domain
KUC3_15320	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_15330	COG2351	hydroxyisourate hydrolase activity
KUC3_15360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KUC3_15380	COG1309	transcriptional regulator
KUC3_15410	COG2252	PERMEase
KUC3_15420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KUC3_15460	COG2205	protein histidine kinase activity
KUC3_15460	COG0784	Response regulator, receiver
KUC3_15490	COG2233	PERMEase
KUC3_15520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KUC3_15530	COG0730	response to heat
KUC3_15550	COG0154	amidase activity
KUC3_15610	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_15620	COG3001	Fructosamine kinase
KUC3_15640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KUC3_15680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KUC3_15700	COG1596	polysaccharide export
KUC3_15710	COG0489	protein tyrosine kinase activity
KUC3_15720	COG4464	protein tyrosine phosphatase activity
KUC3_15770	COG5001	Diguanylate cyclase
KUC3_15880	COG0463	Glycosyl transferase, family 2
KUC3_15910	COG0072	phenylalanine-tRNA ligase activity
KUC3_15910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC3_15970	COG1472	Belongs to the glycosyl hydrolase 3 family
KUC3_15990	COG2096	Adenosyltransferase
KUC3_16010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KUC3_16030	COG4591	ABC-type transport system involved in lipoprotein release permease component
KUC3_16040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KUC3_16080	COG0708	Exodeoxyribonuclease III
KUC3_16190	COG2814	Major facilitator Superfamily
KUC3_16260	COG4770	biotin carboxylase activity
KUC3_16280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUC3_16290	COG1960	acyl-CoA dehydrogenase activity
KUC3_16300	COG0789	Transcriptional regulator
KUC3_16310	COG0183	Belongs to the thiolase family
KUC3_16360	COG2925	Exonuclease
KUC3_16410	COG1643	Atp-dependent helicase
KUC3_16450	COG0604	alcohol dehydrogenase
KUC3_16450	COG3321	synthase
KUC3_16460	COG0328	RNA-DNA hybrid ribonuclease activity
KUC3_16470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KUC3_16490	COG1136	(ABC) transporter
KUC3_16500	COG4591	ABC-type transport system involved in lipoprotein release permease component
KUC3_16510	COG1301	dicarboxylic acid transport
KUC3_16530	COG3724	N-succinylarginine dihydrolase activity
KUC3_16550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KUC3_16560	COG3122	Protein conserved in bacteria
KUC3_16590	COG1609	Transcriptional regulator
KUC3_16630	COG0800	Aldolase
KUC3_16640	COG2271	Major facilitator Superfamily
KUC3_16650	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_16670	COG5285	phytanoyl-CoA dioxygenase
KUC3_16720	COG3119	arylsulfatase activity
KUC3_16850	COG2124	cytochrome p450
KUC3_16890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KUC3_16900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KUC3_16910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KUC3_16920	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_16930	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_16940	COG1063	alcohol dehydrogenase
KUC3_16950	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_16970	COG3386	PFAM SMP-30 Gluconolaconase
KUC3_16980	COG2814	Major facilitator Superfamily
KUC3_16990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC3_17020	COG0625	glutathione transferase activity
KUC3_17050	COG0826	peptidase U32
KUC3_17060	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KUC3_17070	COG2153	protein acetylation
KUC3_17130	COG5002	protein histidine kinase activity
KUC3_17160	COG1530	ribonuclease E activity
KUC3_17170	COG1530	ribonuclease E activity
KUC3_17180	COG1530	ribonuclease E activity
KUC3_17200	COG0564	pseudouridine synthase activity
KUC3_17210	COG0546	phosphoglycolate phosphatase activity
KUC3_17240	COG0424	maF-like protein
KUC3_17250	COG1399	metal-binding, possibly nucleic acid-binding protein
KUC3_17270	COG0416	fatty acid biosynthetic process
KUC3_17280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KUC3_17290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KUC3_17310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KUC3_17320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KUC3_17340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KUC3_17370	COG0084	hydrolase, TatD family'
KUC3_17380	COG0259	pyridoxamine-phosphate oxidase activity
KUC3_17390	COG0702	epimerase
KUC3_17440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KUC3_17450	COG1609	Transcriptional regulator
KUC3_17520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_17540	COG4771	TonB-dependent receptor
KUC3_17640	COG1238	metal cluster binding
KUC3_17680	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KUC3_17690	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KUC3_17700	COG0436	Aminotransferase
KUC3_17730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_17750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUC3_17760	COG1765	OsmC-like protein
KUC3_17770	COG2996	Protein conserved in bacteria
KUC3_17790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KUC3_17800	COG1984	allophanate hydrolase subunit 2
KUC3_17820	COG0735	belongs to the Fur family
KUC3_17840	COG0716	FMN binding
KUC3_17860	COG0596	Alpha beta hydrolase
KUC3_17970	COG1960	acyl-CoA dehydrogenase activity
KUC3_17980	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_17990	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_18000	COG1671	Belongs to the UPF0178 family
KUC3_18020	COG0840	transmembrane signaling receptor activity
KUC3_18040	COG1448	Aminotransferase
KUC3_18130	COG1024	Enoyl-CoA hydratase
KUC3_18140	COG0405	Gamma-glutamyltransferase
KUC3_18430	COG3547	Transposase (IS116 IS110 IS902 family)
KUC3_18500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KUC3_18540	COG0534	Mate efflux family protein
KUC3_18550	COG0303	'Molybdopterin
KUC3_18570	COG0366	Alpha amylase catalytic
KUC3_18580	COG1215	transferase activity, transferring glycosyl groups
KUC3_18590	COG3769	mannosylglycerate metabolic process
KUC3_18600	COG0572	uridine kinase
KUC3_18660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KUC3_18730	COG1393	Belongs to the ArsC family
KUC3_18750	COG4783	chaperone-mediated protein folding
KUC3_18770	COG0583	DNA-binding transcription factor activity
KUC3_18800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KUC3_18820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUC3_18830	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KUC3_18890	COG3239	Fatty acid desaturase
KUC3_18910	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_18920	COG0583	DNA-binding transcription factor activity
KUC3_18940	COG0633	Ferredoxin
KUC3_18950	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KUC3_18960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KUC3_18970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC3_18990	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KUC3_19000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KUC3_19010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KUC3_19020	COG0539	negative regulation of cytoplasmic translation
KUC3_19030	COG0776	regulation of translation
KUC3_19050	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KUC3_19060	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KUC3_19070	COG0284	orotidine-5'-phosphate decarboxylase activity
KUC3_19080	COG0686	Belongs to the AlaDH PNT family
KUC3_19100	COG1674	ftsk spoiiie
KUC3_19100	COG0531	amino acid
KUC3_19110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KUC3_19120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KUC3_19210	COG2920	part of a sulfur-relay system
KUC3_19240	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KUC3_19250	COG0670	Belongs to the BI1 family
KUC3_19290	COG0583	DNA-binding transcription factor activity
KUC3_19300	COG2259	Doxx family
KUC3_19310	COG3384	dioxygenase
KUC3_19320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KUC3_19340	COG1741	Belongs to the pirin family
KUC3_19350	COG2197	response regulator
KUC3_19360	COG0322	excinuclease ABC activity
KUC3_19390	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KUC3_19400	COG3148	PFAM DTW domain containing protein
KUC3_19410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KUC3_19420	COG2897	thiosulfate sulfurtransferase activity
KUC3_19440	COG1280	lysine exporter protein (LysE YggA)
KUC3_19480	COG1752	Esterase of the alpha-beta hydrolase superfamily
KUC3_19490	COG0037	tRNA processing
KUC3_19500	COG0589	response to stress
KUC3_19540	COG2217	Heavy metal translocating P-type atpase
KUC3_19560	COG2010	Cytochrome c
KUC3_19590	COG3278	Belongs to the heme-copper respiratory oxidase family
KUC3_19610	COG2193	ferroxidase activity
KUC3_19640	COG0069	glutamate synthase activity
KUC3_19660	COG0589	response to stress
KUC3_19670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KUC3_19690	COG4974	Belongs to the 'phage' integrase family
KUC3_19790	COG1082	Xylose isomerase domain protein TIM barrel
KUC3_19840	COG0534	Mate efflux family protein
KUC3_19860	COG3046	protein related to deoxyribodipyrimidine photolyase
KUC3_19870	COG0415	Belongs to the DNA photolyase family
KUC3_19880	COG0415	Belongs to the DNA photolyase family
KUC3_19890	COG0415	Belongs to the DNA photolyase family
KUC3_19910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KUC3_19920	COG3130	regulation of translation
KUC3_19940	COG0488	(ABC) transporter
KUC3_19970	COG0167	dihydroorotate dehydrogenase activity
KUC3_19980	COG2902	Dehydrogenase
KUC3_20040	COG0308	aminopeptidase N
KUC3_20050	COG1757	Na H antiporter
KUC3_20060	COG0733	neurotransmitter:sodium symporter activity
KUC3_20070	COG0793	Belongs to the peptidase S41A family
KUC3_20100	COG1956	GAF domain-containing protein
KUC3_20120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KUC3_20140	COG1946	Acyl-CoA thioesterase
KUC3_20150	COG0515	serine threonine protein kinase
KUC3_20160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KUC3_20180	COG0022	dehydrogenase e1 component
KUC3_20190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KUC3_20200	COG1404	Belongs to the peptidase S8 family
KUC3_20210	COG1322	Protein conserved in bacteria
KUC3_20240	COG0494	nUDIX hydrolase
KUC3_20250	COG1760	l-serine dehydratase
KUC3_20300	COG0583	DNA-binding transcription factor activity
KUC3_20310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KUC3_20320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KUC3_20330	COG0513	Belongs to the DEAD box helicase family
KUC3_20350	COG1054	Belongs to the UPF0176 family
KUC3_20380	COG2207	Transcriptional regulator
KUC3_20390	COG1073	alpha beta
KUC3_20410	COG0205	6-phosphofructokinase activity
KUC3_20430	COG3279	Response regulator of the LytR AlgR family
KUC3_20440	COG3275	phosphorelay sensor kinase activity
KUC3_20500	COG3081	Nucleoid-associated protein
KUC3_20510	COG3082	Protein of unknown function (DUF1414)
KUC3_20520	COG3083	sulfuric ester hydrolase activity
KUC3_20530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KUC3_20550	COG1024	Enoyl-CoA hydratase
KUC3_20560	COG1960	acyl-CoA dehydrogenase activity
KUC3_20580	COG2084	Dehydrogenase
KUC3_20590	COG0386	Belongs to the glutathione peroxidase family
KUC3_20600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KUC3_20610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC3_20620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KUC3_20650	COG0616	signal peptide processing
KUC3_20670	COG2267	carboxylic ester hydrolase activity
KUC3_20680	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_20700	COG1609	Transcriptional regulator
KUC3_20730	COG0366	Alpha amylase catalytic
KUC3_20780	COG4667	esterase of the alpha-beta hydrolase superfamily
KUC3_20890	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC3_20900	COG0567	Dehydrogenase, E1 component
KUC3_20910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KUC3_20920	COG1053	succinate dehydrogenase
KUC3_20930	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KUC3_20950	COG0372	Belongs to the citrate synthase family
KUC3_20990	COG0435	Glutathione S-transferase
KUC3_21000	COG0579	oxidoreductase
KUC3_21010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KUC3_21090	COG1663	tetraacyldisaccharide 4'-kinase activity
KUC3_21100	COG1132	(ABC) transporter
KUC3_21110	COG2333	competence protein COMEC
KUC3_21110	COG0658	competence protein
KUC3_21130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KUC3_21150	COG1196	nuclear chromosome segregation
KUC3_21160	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KUC3_21340	COG2226	methyltransferase
KUC3_21540	COG1185	polyribonucleotide nucleotidyltransferase activity
KUC3_21570	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KUC3_21580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KUC3_21590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_21620	COG0561	phosphatase activity
KUC3_21630	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_21650	COG1597	lipid kinase activity
KUC3_21650	COG1803	Methylglyoxal synthase
KUC3_21660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KUC3_21700	COG3706	GGDEF domain
KUC3_21710	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KUC3_21720	COG0149	triose-phosphate isomerase activity
KUC3_21730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KUC3_21740	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KUC3_21750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUC3_21760	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KUC3_21770	COG1534	Rna-binding protein
KUC3_21800	COG1067	ATP-dependent peptidase activity
KUC3_21820	COG0495	leucyl-tRNA aminoacylation
KUC3_21830	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
KUC3_21840	COG1466	dna polymerase III delta subunit
KUC3_21850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KUC3_21860	COG0799	negative regulation of ribosome biogenesis
KUC3_21870	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KUC3_21880	COG0768	penicillin binding
KUC3_21890	COG0772	Belongs to the SEDS family
KUC3_21900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KUC3_21910	COG1686	Belongs to the peptidase S11 family
KUC3_21920	COG2921	Belongs to the UPF0250 family
KUC3_21930	COG0321	lipoyl(octanoyl) transferase activity
KUC3_21940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KUC3_21950	COG0252	asparaginase activity
KUC3_21990	COG0778	Nitroreductase
KUC3_22020	COG0616	signal peptide processing
KUC3_22030	COG3092	negative regulation of chromosome organization
KUC3_22040	COG0492	ferredoxin-NADP+ reductase activity
KUC3_22050	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KUC3_22060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KUC3_22070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KUC3_22080	COG0542	response to heat
KUC3_22090	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KUC3_22100	COG1278	Cold shock
KUC3_22120	COG1187	pseudouridine synthase activity
KUC3_22130	COG0482	sulfurtransferase activity
KUC3_22140	COG2915	High frequency lysogenization protein hflD homolog
KUC3_22150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KUC3_22170	COG2850	peptidyl-arginine hydroxylation
KUC3_22240	COG0574	Belongs to the PEP-utilizing enzyme family
KUC3_22240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KUC3_22270	COG0457	Tetratricopeptide repeat
KUC3_22280	COG4771	TonB-dependent receptor
KUC3_22290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUC3_22310	COG2914	Belongs to the UPF0125 (RnfH) family
KUC3_22320	COG2867	negative regulation of translational initiation
KUC3_22340	COG1902	pentaerythritol trinitrate reductase activity
KUC3_22350	COG3706	GGDEF domain
KUC3_22370	COG1131	(ABC) transporter
KUC3_22430	COG0583	DNA-binding transcription factor activity
KUC3_22510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KUC3_22520	COG4136	ATPase activity
KUC3_22530	COG4135	transport system, permease component
KUC3_22540	COG4134	Bacterial extracellular solute-binding protein
KUC3_22560	COG4771	TonB-dependent receptor
KUC3_22590	COG1032	radical SAM domain protein
KUC3_22740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC3_22740	COG3153	acetyltransferase
KUC3_22800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KUC3_22830	COG0195	Participates in both transcription termination and antitermination
KUC3_22850	COG3437	response regulator, receiver
KUC3_22860	COG0784	Response regulator, receiver
KUC3_22860	COG2205	protein histidine kinase activity
KUC3_22860	COG2198	Histidine kinase
KUC3_22910	COG2205	protein histidine kinase activity
KUC3_22920	COG0745	RESPONSE REGULATOR receiver
KUC3_22940	COG4771	TonB-dependent receptor
KUC3_22950	COG0668	transmembrane transport
KUC3_23070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUC3_23130	COG0596	Alpha beta hydrolase
KUC3_23140	COG1960	acyl-CoA dehydrogenase activity
KUC3_23150	COG0183	Belongs to the thiolase family
KUC3_23170	COG0596	Alpha beta hydrolase
KUC3_23180	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_23210	COG0366	Alpha amylase catalytic
KUC3_23220	COG0604	alcohol dehydrogenase
KUC3_23240	COG1960	acyl-CoA dehydrogenase activity
KUC3_23260	COG4771	TonB-dependent receptor
KUC3_23310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KUC3_23350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KUC3_23360	COG0315	cyclic pyranopterin monophosphate synthase activity
KUC3_23370	COG0521	Mo-molybdopterin cofactor biosynthetic process
KUC3_23380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KUC3_23420	COG0436	Aminotransferase
KUC3_23430	COG3268	Saccharopine dehydrogenase
KUC3_23450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KUC3_23450	COG1017	nitric oxide dioxygenase activity
KUC3_23470	COG3604	Transcriptional regulator
KUC3_23520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC3_23550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KUC3_23560	COG1074	ATP-dependent DNA helicase activity
KUC3_23570	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KUC3_23590	COG1022	Amp-dependent synthetase and ligase
KUC3_23600	COG3300	MHYT domain
KUC3_23600	COG5001	Diguanylate cyclase
KUC3_23630	COG0583	DNA-binding transcription factor activity
KUC3_23670	COG0640	Transcriptional regulator
KUC3_23690	COG0583	DNA-binding transcription factor activity
KUC3_23700	COG3932	Exopolysaccharide synthesis, ExoD
KUC3_23710	COG2204	response regulator
KUC3_23730	COG4251	negative regulation of phosphorylation
KUC3_23740	COG0784	Response regulator, receiver
KUC3_23750	COG0784	Response regulator, receiver
KUC3_23750	COG2205	protein histidine kinase activity
KUC3_23810	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KUC3_23860	COG3139	Protein of unknown function (DUF1315)
KUC3_23880	COG1115	amino acid carrier protein
KUC3_23890	COG2866	Carboxypeptidase
KUC3_23930	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KUC3_23950	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KUC3_23960	COG1640	4-alpha-glucanotransferase
KUC3_23980	COG0676	glucose-6-phosphate 1-epimerase activity
KUC3_23990	COG0800	Aldolase
KUC3_24010	COG0129	dihydroxy-acid dehydratase activity
KUC3_24030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KUC3_24040	COG1737	Transcriptional regulator
KUC3_24050	COG0469	pyruvate kinase activity
KUC3_24110	COG2205	protein histidine kinase activity
KUC3_24110	COG0784	Response regulator, receiver
KUC3_24140	COG2356	endonuclease I
KUC3_24200	COG0583	DNA-binding transcription factor activity
KUC3_24220	COG1979	alcohol dehydrogenase
KUC3_24230	COG5001	Diguanylate cyclase
KUC3_24250	COG0753	catalase activity
KUC3_24260	COG0784	Response regulator, receiver
KUC3_24260	COG3437	response regulator, receiver
KUC3_24270	COG4191	Histidine kinase
KUC3_24270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_24340	COG0778	Nitroreductase
KUC3_24380	COG0330	HflC and HflK could
KUC3_24440	COG0431	NADPH-dependent FMN reductase
KUC3_24450	COG1741	Belongs to the pirin family
KUC3_24460	COG0583	DNA-binding transcription factor activity
KUC3_24490	COG0471	metal ion transport
KUC3_24520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC3_24520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUC3_24530	COG2226	methyltransferase
KUC3_24540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC3_24550	COG0741	lytic transglycosylase activity
KUC3_24550	COG1388	LysM domain
KUC3_24590	COG0215	cysteine-tRNA ligase activity
KUC3_24600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KUC3_24610	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUC3_24620	COG1785	Belongs to the alkaline phosphatase family
KUC3_24630	COG1785	Belongs to the alkaline phosphatase family
KUC3_24660	COG2268	Band 7 protein
KUC3_24680	COG1136	(ABC) transporter
KUC3_24720	COG2205	protein histidine kinase activity
KUC3_24780	COG0604	alcohol dehydrogenase
KUC3_24790	COG0583	DNA-binding transcription factor activity
KUC3_24860	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KUC3_24870	COG1286	toxin biosynthetic process
KUC3_24880	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KUC3_24890	COG0285	dihydrofolate synthase activity
KUC3_24920	COG0101	tRNA pseudouridine synthase activity
KUC3_24950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KUC3_24980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KUC3_25000	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KUC3_25000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUC3_25040	COG1119	ATPase activity
KUC3_25060	COG0612	Peptidase, M16
KUC3_25080	COG2031	fatty acid transporter
KUC3_25110	COG3101	peptidyl-lysine hydroxylation
KUC3_25190	COG3119	arylsulfatase activity
KUC3_25270	COG4948	Mandelate Racemase Muconate Lactonizing
KUC3_25290	COG3119	arylsulfatase activity
KUC3_25300	COG3119	arylsulfatase activity
KUC3_25310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUC3_25320	COG0800	Aldolase
KUC3_25340	COG2814	Major facilitator Superfamily
KUC3_25350	COG1609	Transcriptional regulator
KUC3_25360	COG4771	TonB-dependent receptor
KUC3_25390	COG1902	pentaerythritol trinitrate reductase activity
KUC3_25390	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC3_25440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KUC3_25460	COG4399	Belongs to the UPF0754 family
KUC3_25520	COG2186	Transcriptional regulator
KUC3_25540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KUC3_25550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KUC3_25560	COG2983	Belongs to the UPF0260 family
KUC3_25570	COG0179	Fumarylacetoacetate (FAA) hydrolase
KUC3_25600	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KUC3_25610	COG0318	PFAM AMP-dependent synthetase and ligase
KUC3_25620	COG2267	carboxylic ester hydrolase activity
KUC3_25650	COG1214	PFAM Peptidase M22, glycoprotease
KUC3_25660	COG1199	ATP-dependent helicase activity
KUC3_25690	COG0671	phosphoesterase, PA-phosphatase related
KUC3_25760	COG1192	Involved in chromosome partitioning
KUC3_25780	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KUC3_25790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KUC3_25800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KUC3_25810	COG0131	Imidazoleglycerol-phosphate dehydratase
KUC3_25810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KUC3_25820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KUC3_25870	COG0583	DNA-binding transcription factor activity
KUC3_25880	COG0612	Peptidase, M16
KUC3_25890	COG0681	Belongs to the peptidase S26 family
KUC3_25930	COG0326	Molecular chaperone. Has ATPase activity
KUC3_25940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KUC3_25980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KUC3_25990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KUC3_26010	COG3220	belongs to the UPF0276 family
KUC3_26040	COG1183	phosphatidylcholine synthase activity
KUC3_26070	COG0457	Tetratricopeptide repeat
KUC3_26080	COG0277	FAD linked oxidase domain protein
KUC3_26090	COG0542	response to heat
KUC3_26120	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_26140	COG1595	DNA-templated transcription, initiation
KUC3_26170	COG4221	oxidoreductase activity
KUC3_26180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KUC3_26200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KUC3_26220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KUC3_26240	COG0142	geranyltranstransferase activity
KUC3_26260	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KUC3_26270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KUC3_26290	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KUC3_26320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUC3_26320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUC3_26350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUC3_26360	COG0488	(ABC) transporter
KUC3_26380	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KUC3_26400	COG0560	Phosphoserine phosphatase
KUC3_26420	COG0084	hydrolase, TatD family'
KUC3_26440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KUC3_26450	COG0571	ribonuclease III activity
KUC3_26490	COG3026	antisigma factor binding
KUC3_26510	COG1595	DNA-templated transcription, initiation
KUC3_26520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KUC3_26550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KUC3_26570	COG1047	Peptidyl-prolyl cis-trans
KUC3_26710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KUC3_26720	COG1047	Peptidyl-prolyl cis-trans
KUC3_26740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KUC3_26750	COG0196	riboflavin kinase activity
KUC3_26760	COG0728	peptidoglycan biosynthetic process
KUC3_26770	COG0728	peptidoglycan biosynthetic process
KUC3_26780	COG0268	Binds directly to 16S ribosomal RNA
KUC3_26810	COG1028	Short-chain dehydrogenase reductase Sdr
KUC3_26820	COG0385	Bile acid
KUC3_26880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC3_26890	COG0776	regulation of translation
KUC3_26900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KUC3_26920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KUC3_26930	COG0740	serine-type endopeptidase activity
KUC3_26940	COG0544	peptidyl-prolyl cis-trans isomerase activity
KUC3_26970	COG1720	tRNA m6t6A37 methyltransferase activity
KUC3_26990	COG1234	tRNA 3'-trailer cleavage
KUC3_27010	COG0123	including yeast histone deacetylase and acetoin utilization protein
KUC3_27040	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KUC3_27070	COG1858	cytochrome C peroxidase
KUC3_27130	COG0516	GMP reductase activity
KUC3_27130	COG0517	IMP dehydrogenase activity
KUC3_27140	COG1570	exodeoxyribonuclease VII activity
KUC3_27190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUC3_27200	COG2976	Protein conserved in bacteria
KUC3_27240	COG3063	Type IV pilus biogenesis stability protein PilW
KUC3_27250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KUC3_27270	COG2166	iron-sulfur cluster assembly
KUC3_27300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KUC3_27310	COG0719	Fe-S assembly protein
KUC3_27320	COG0396	ATPase activity
KUC3_27330	COG0719	Fe-S assembly protein
KUC3_27340	COG1104	cysteine desulfurase activity
KUC3_27350	COG1959	2 iron, 2 sulfur cluster binding
KUC3_27360	COG1045	serine acetyltransferase
KUC3_27370	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KUC3_27380	COG0483	inositol monophosphate 1-phosphatase activity
KUC3_27410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC3_27420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUC3_27430	COG1862	Preprotein translocase
KUC3_27440	COG0343	queuine tRNA-ribosyltransferase activity
KUC3_27480	COG1842	Phage shock protein A
KUC3_27490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KUC3_27530	COG0754	glutathionylspermidine amidase activity
KUC3_27560	COG1136	(ABC) transporter
KUC3_27590	COG2066	Belongs to the glutaminase family
KUC3_27600	COG1785	Belongs to the alkaline phosphatase family
KUC3_27610	COG0745	RESPONSE REGULATOR receiver
KUC3_27780	COG0438	transferase activity, transferring glycosyl groups
KUC3_27870	COG0297	glycogen (starch) synthase activity
KUC3_27900	COG0367	asparagine synthase
KUC3_27960	COG0367	asparagine synthase
KUC3_28030	COG0489	protein tyrosine kinase activity
KUC3_28050	COG3267	Type II secretory pathway component ExeA
KUC3_28050	COG3409	Peptidoglycan-binding domain 1 protein
KUC3_28060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KUC3_28060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KUC3_28110	COG1560	Kdo2-lipid A biosynthetic process
KUC3_28140	COG1960	acyl-CoA dehydrogenase activity
KUC3_28170	COG1435	thymidine kinase activity
KUC3_28190	COG1609	Transcriptional regulator
KUC3_28200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KUC3_28240	COG1082	Xylose isomerase domain protein TIM barrel
KUC3_28260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC3_28290	COG1982	Orn Lys Arg decarboxylase major
KUC3_28320	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_28360	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KUC3_28370	COG0789	Transcriptional regulator
KUC3_28440	COG1960	acyl-CoA dehydrogenase activity
KUC3_28570	COG4771	TonB-dependent receptor
KUC3_28600	COG1295	ribonuclease BN
KUC3_28640	COG3279	Response regulator of the LytR AlgR family
KUC3_28650	COG2819	hydrolase of the alpha beta superfamily
KUC3_28670	COG4977	sequence-specific DNA binding
KUC3_28670	COG1917	Cupin 2, conserved barrel domain protein
KUC3_28730	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC3_28930	COG4650	regulator
KUC3_28950	COG1690	Belongs to the RtcB family
KUC3_28960	COG0430	RNA-3'-phosphate cyclase activity
KUC3_28970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KUC3_28980	COG1690	Belongs to the RtcB family
KUC3_29000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KUC3_29000	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
KUC3_29030	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KUC3_29090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KUC3_29090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KUC3_29130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KUC3_29150	COG0738	Major facilitator superfamily
KUC3_29160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KUC3_29170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KUC3_29180	COG2971	BadF BadG BcrA BcrD
KUC3_29210	COG1609	Transcriptional regulator
KUC3_29230	COG0583	DNA-binding transcription factor activity
KUC3_29270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC3_29280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUC3_29290	COG0006	proline dipeptidase activity
KUC3_29310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC3_29330	COG0784	Response regulator, receiver
KUC3_29330	COG2198	Histidine kinase
KUC3_29330	COG5002	protein histidine kinase activity
KUC3_29340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KUC3_29360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KUC3_29370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KUC3_29410	COG3313	Fe-S protein
KUC3_29470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC3_29480	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC3_29490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KUC3_29530	COG3577	Aspartyl protease
KUC3_29540	COG0157	Belongs to the NadC ModD family
KUC3_29560	COG1459	type II secretion system
KUC3_29570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KUC3_29580	COG0237	dephospho-CoA kinase activity
KUC3_29590	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KUC3_29600	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KUC3_29620	COG1902	pentaerythritol trinitrate reductase activity
KUC3_29620	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC3_29630	COG2988	succinylglutamate desuccinylase activity
KUC3_29640	COG0494	nUDIX hydrolase
KUC3_29660	COG0739	heme binding
KUC3_29670	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KUC3_29680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KUC3_29690	COG0849	cell division
KUC3_29700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KUC3_29710	COG1181	Belongs to the D-alanine--D-alanine ligase family
KUC3_29720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KUC3_29740	COG0772	Belongs to the SEDS family
KUC3_29750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KUC3_29770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KUC3_29780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KUC3_29790	COG0768	penicillin binding
KUC3_29800	COG3116	cell division
KUC3_29820	COG2001	Belongs to the MraZ family
KUC3_29870	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUC3_29920	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KUC3_29920	COG0678	peroxiredoxin activity
KUC3_29970	COG2204	response regulator
KUC3_30040	COG0668	transmembrane transport
KUC3_30050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KUC3_30060	COG0189	ligase activity
KUC3_30070	COG1678	Uncharacterized ACR, COG1678
KUC3_30080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KUC3_30130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KUC3_30140	COG0762	integral membrane protein
KUC3_30200	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUC3_30200	COG1902	pentaerythritol trinitrate reductase activity
KUC3_30240	COG0625	glutathione transferase activity
KUC3_30260	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KUC3_30290	COG2378	regulation of single-species biofilm formation
KUC3_30340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KUC3_30360	COG0083	homoserine kinase activity
KUC3_30370	COG0460	homoserine dehydrogenase
KUC3_30370	COG0527	aspartate kinase activity
KUC3_30390	COG0583	DNA-binding transcription factor activity
KUC3_30410	COG2197	response regulator
KUC3_30420	COG4585	Histidine kinase
KUC3_30450	COG0840	transmembrane signaling receptor activity
KUC3_30460	COG0640	Transcriptional regulator
KUC3_30480	COG0431	NADPH-dependent FMN reductase
KUC3_30490	COG0798	PFAM Bile acid sodium symporter
KUC3_30500	COG2197	response regulator
KUC3_30510	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KUC3_30530	COG3850	Histidine kinase
KUC3_30530	COG5002	protein histidine kinase activity
KUC3_30580	COG1748	Saccharopine dehydrogenase
KUC3_30600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KUC3_30610	COG3107	peptidoglycan biosynthetic process
KUC3_30640	COG2823	Periplasmic or secreted lipoprotein
KUC3_30680	COG4585	Histidine kinase
KUC3_30690	COG2197	response regulator
KUC3_30720	COG1802	Transcriptional regulator
KUC3_30730	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KUC3_30740	COG0372	Belongs to the citrate synthase family
KUC3_30750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KUC3_30770	COG2828	Protein conserved in bacteria
KUC3_30780	COG2203	Gaf domain
KUC3_30780	COG2199	diguanylate cyclase activity
KUC3_30810	COG0784	Response regulator, receiver
KUC3_30810	COG2198	Histidine kinase
KUC3_30810	COG5002	protein histidine kinase activity
KUC3_30820	COG3023	N-Acetylmuramoyl-L-alanine amidase
KUC3_30830	COG0067	glutamate synthase
KUC3_30830	COG0069	glutamate synthase activity
KUC3_30830	COG0070	glutamate synthase
KUC3_30840	COG0493	'glutamate synthase
KUC3_30850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KUC3_30890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KUC3_30900	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KUC3_30910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KUC3_30920	COG1054	Belongs to the UPF0176 family
KUC3_30950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUC3_30960	COG5507	3-demethylubiquinone-9 3-methyltransferase
KUC3_30970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KUC3_30980	COG0739	heme binding
KUC3_30980	COG0741	lytic transglycosylase activity
KUC3_30980	COG1196	nuclear chromosome segregation
KUC3_30990	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KUC3_31040	COG0625	glutathione transferase activity
KUC3_31080	COG2326	polyphosphate kinase activity
KUC3_31110	COG1215	transferase activity, transferring glycosyl groups
KUC3_31140	COG2204	response regulator
KUC3_31170	COG2894	cell division
KUC3_31180	COG0850	regulation of cytokinetic process
KUC3_31220	COG1981	membrane
KUC3_31250	COG1914	H( )-stimulated, divalent metal cation uptake system
KUC3_31280	COG1217	gtp-binding protein TYPA
KUC3_31290	COG0174	glutamine synthetase
KUC3_31310	COG3852	Histidine kinase
KUC3_31340	COG3437	response regulator, receiver
KUC3_31410	COG0525	valine-tRNA ligase activity
KUC3_31420	COG2927	DNA polymerase III (CHI subunit)
KUC3_31430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KUC3_31440	COG0795	lipopolysaccharide-transporting ATPase activity
KUC3_31450	COG0795	lipopolysaccharide-transporting ATPase activity
KUC3_31470	COG0673	inositol 2-dehydrogenase activity
KUC3_31640	COG0464	growth
KUC3_31740	COG3341	Caulimovirus viroplasmin
KUC3_31740	COG0328	RNA-DNA hybrid ribonuclease activity
KUC3_31770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUC3_31820	COG0210	DNA helicase
KUC3_32060	COG0745	RESPONSE REGULATOR receiver
KUC3_32100	COG1024	Enoyl-CoA hydratase
KUC3_32150	COG1215	transferase activity, transferring glycosyl groups
KUC3_32160	COG0438	transferase activity, transferring glycosyl groups
KUC3_32300	COG0277	FAD linked oxidase domain protein
KUC3_32410	COG0513	Belongs to the DEAD box helicase family
KUC3_32470	COG2200	EAL domain
KUC3_32470	COG2199	diguanylate cyclase activity
KUC3_32470	COG2202	Pas domain
KUC3_32490	COG3568	Endonuclease Exonuclease Phosphatase
KUC3_32520	COG0730	response to heat
KUC3_32530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KUC3_32560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_32560	COG4191	Histidine kinase
KUC3_32580	COG0417	DNA replication proofreading
KUC3_32680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC3_32700	COG1573	uracil-dna glycosylase
KUC3_32710	COG5001	Diguanylate cyclase
KUC3_32710	COG3300	MHYT domain
KUC3_32750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KUC3_32790	COG1983	PspC domain protein
KUC3_32800	COG1842	Phage shock protein A
KUC3_32830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC3_32860	COG0542	response to heat
KUC3_32890	COG0204	Acyl-transferase
KUC3_32900	COG0204	Acyl-transferase
KUC3_32910	COG0668	transmembrane transport
KUC3_32940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KUC3_32950	COG0733	neurotransmitter:sodium symporter activity
KUC3_32980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KUC3_33030	COG0848	biopolymer transport protein
KUC3_33050	COG0457	Tetratricopeptide repeat
KUC3_33060	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KUC3_33110	COG0702	epimerase
KUC3_33150	COG5001	Diguanylate cyclase
KUC3_33150	COG5002	protein histidine kinase activity
KUC3_33170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KUC3_33190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC3_33210	COG0583	DNA-binding transcription factor activity
KUC3_33220	COG0121	glutamine amidotransferase
KUC3_33240	COG4682	membrane
KUC3_33280	COG4628	conserved protein (DUF2132)
KUC3_33290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUC3_33310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KUC3_33330	COG1477	protein flavinylation
KUC3_33340	COG2871	sodium ion transport
KUC3_33350	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_33360	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_33370	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_33380	COG1805	sodium ion transport
KUC3_33390	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KUC3_33400	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KUC3_33410	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC3_33420	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KUC3_33460	COG0039	L-malate dehydrogenase activity
KUC3_33470	COG1438	arginine binding
KUC3_33520	COG0572	uridine kinase
KUC3_33530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KUC3_33580	COG0517	IMP dehydrogenase activity
KUC3_33580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KUC3_33590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_33610	COG0784	Response regulator, receiver
KUC3_33610	COG2205	protein histidine kinase activity
KUC3_33630	COG0189	ligase activity
KUC3_33650	COG0189	ligase activity
KUC3_33650	COG4067	protein conserved in archaea
KUC3_33680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KUC3_33700	COG1283	sodium-dependent phosphate transmembrane transporter activity
KUC3_33710	COG0667	Aldo Keto reductase
KUC3_33750	COG3300	MHYT domain
KUC3_33750	COG5001	Diguanylate cyclase
KUC3_33770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KUC3_33790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KUC3_33800	COG0840	transmembrane signaling receptor activity
KUC3_33850	COG0583	DNA-binding transcription factor activity
KUC3_33880	COG0438	transferase activity, transferring glycosyl groups
KUC3_33880	COG1216	Glycosyl transferase, family 2
KUC3_33970	COG1216	Glycosyl transferase, family 2
KUC3_33970	COG1442	glycosyl transferase family 8
KUC3_33990	COG0463	Glycosyl transferase, family 2
KUC3_34090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KUC3_34100	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KUC3_34150	COG0202	RNA polymerase activity
KUC3_34190	COG0201	protein transport
KUC3_34230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KUC3_34300	COG0784	Response regulator, receiver
KUC3_34300	COG2205	protein histidine kinase activity
KUC3_34330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUC3_34340	COG0557	exoribonuclease II activity
KUC3_34390	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KUC3_34490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KUC3_34510	COG4251	negative regulation of phosphorylation
KUC3_34550	COG3706	GGDEF domain
KUC3_34580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KUC3_34580	COG0456	acetyltransferase
KUC3_34610	COG0583	DNA-binding transcription factor activity
KUC3_34650	COG1271	oxidase subunit
KUC3_34660	COG1294	oxidase, subunit
KUC3_34690	COG1522	sequence-specific DNA binding
KUC3_34710	COG1278	Cold shock
KUC3_34720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KUC3_34760	COG0339	signal peptide processing
KUC3_34770	COG2201	protein-glutamate methylesterase activity
KUC3_34790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUC3_34790	COG4191	Histidine kinase
KUC3_34810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUC3_34820	COG3437	response regulator, receiver
KUC3_34840	COG4946	Tricorn protease homolog
KUC3_34840	COG1506	peptidase
KUC3_34840	COG0823	Involved in the tonB-independent uptake of proteins
KUC3_34910	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KUC3_34920	COG1278	Cold shock
KUC3_34960	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KUC3_34970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KUC3_35000	COG0281	malic enzyme
KUC3_35020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KUC3_35080	COG0456	acetyltransferase
KUC3_35100	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KUC3_35110	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KUC3_35120	COG2177	Part of the ABC transporter FtsEX involved in
KUC3_35130	COG2884	Cell division ATP-binding protein ftsE
KUC3_35140	COG0552	protein localization to endoplasmic reticulum
KUC3_35150	COG0742	ribosomal rna small subunit methyltransferase
KUC3_35170	COG2095	MarC family integral membrane protein
KUC3_35210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KUC3_35220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUC3_35240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KUC3_35270	COG0076	glutamate decarboxylase activity
KUC3_35300	COG0842	Transport permease protein
KUC3_35310	COG1131	(ABC) transporter
KUC3_35320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KUC3_35340	COG0745	RESPONSE REGULATOR receiver
KUC3_35350	COG2205	protein histidine kinase activity
KUC3_35360	COG4774	siderophore transport
KUC3_35410	COG1253	flavin adenine dinucleotide binding
KUC3_35420	COG0701	Predicted permease
KUC3_35430	COG1966	Carbon starvation protein
KUC3_35500	COG0848	biopolymer transport protein
KUC3_35540	COG0657	acetylesterase activity
KUC3_35570	COG1733	regulation of RNA biosynthetic process
KUC3_35590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KUC3_35600	COG0049	tRNA binding
KUC3_35610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KUC3_35620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KUC3_35630	COG0085	RNA polymerase activity
KUC3_35640	COG0222	ribosome binding
KUC3_35650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KUC3_35660	COG0081	regulation of translation
KUC3_35670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KUC3_35700	COG0250	Participates in transcription elongation, termination and antitermination
KUC3_35710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KUC3_35720	COG1132	(ABC) transporter
KUC3_35740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KUC3_35750	COG3590	peptidase
KUC3_35780	COG0513	Belongs to the DEAD box helicase family
KUC3_35800	COG0418	dihydroorotase activity
KUC3_35810	COG3040	lipid binding
KUC3_35820	COG4989	oxidoreductase activity
KUC3_35830	COG0346	lactoylglutathione lyase activity
KUC3_35840	COG0668	transmembrane transport
KUC3_35880	COG0302	gtp cyclohydrolase
KUC3_35900	COG2957	Belongs to the agmatine deiminase family
KUC3_35910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUC3_35930	COG1201	RNA secondary structure unwinding
KUC3_35950	COG1793	dna ligase
KUC3_35960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUC3_35990	COG0583	DNA-binding transcription factor activity
KUC3_36010	COG0625	glutathione transferase activity
KUC3_36020	COG0625	glutathione transferase activity
KUC3_36040	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KUC3_36050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUC3_36070	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_36080	COG0028	Belongs to the TPP enzyme family
KUC3_36100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KUC3_36110	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KUC3_36120	COG0330	HflC and HflK could
KUC3_36130	COG0330	HflC and HflK could
KUC3_36140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KUC3_36150	COG1923	regulation of RNA biosynthetic process
KUC3_36160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KUC3_36170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KUC3_36180	COG0860	N-Acetylmuramoyl-L-alanine amidase
KUC3_36190	COG0802	atpase or kinase
KUC3_36200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KUC3_36200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KUC3_36210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KUC3_36240	COG2816	NAD+ diphosphatase activity
KUC3_36260	COG0735	belongs to the Fur family
KUC3_36300	COG0305	Participates in initiation and elongation during chromosome replication
KUC3_36350	COG2258	MOSC domain
KUC3_36440	COG0577	efflux transmembrane transporter activity
KUC3_36440	COG1136	(ABC) transporter
KUC3_36460	COG0840	transmembrane signaling receptor activity
KUC3_36470	COG5002	protein histidine kinase activity
KUC3_36480	COG0840	transmembrane signaling receptor activity
KUC3_36510	COG2855	membrane
KUC3_36530	COG0656	L-ascorbic acid biosynthetic process
KUC3_36570	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUC3_36580	COG4771	TonB-dependent receptor
KUC3_36640	COG1472	Belongs to the glycosyl hydrolase 3 family
KUC3_36670	COG1609	Transcriptional regulator
KUC3_36680	COG2814	Major facilitator Superfamily
KUC3_36680	COG0477	Major facilitator Superfamily
KUC3_36690	COG1618	nucleotide phosphatase activity, acting on free nucleotides
KUC3_36690	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KUC3_36700	COG4988	ABC transporter
KUC3_36710	COG1294	oxidase, subunit
KUC3_36730	COG3829	transcription factor binding
KUC3_36780	COG4319	ketosteroid isomerase
KUC3_36790	COG1335	isochorismatase
KUC3_36810	COG0402	S-adenosylhomocysteine deaminase activity
KUC3_36820	COG1741	Belongs to the pirin family
KUC3_36840	COG4771	TonB-dependent receptor
KUC3_36870	COG1469	GTP cyclohydrolase I activity
KUC3_36950	COG0811	peptide transport
KUC3_37030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KUC3_37100	COG5001	Diguanylate cyclase
KUC3_37100	COG2203	Gaf domain
KUC3_37100	COG3706	GGDEF domain
KUC3_37100	COG4251	negative regulation of phosphorylation
KUC3_37110	COG1477	protein flavinylation
KUC3_37180	COG3237	CsbD-like
KUC3_37210	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUC3_37210	COG0596	Alpha beta hydrolase
KUC3_37260	COG3038	cytochrome b561
KUC3_37270	COG2353	YceI-like domain
KUC3_37280	COG1252	NADH dehydrogenase
KUC3_37330	COG2067	long-chain fatty acid transport protein
KUC3_37340	COG2203	Gaf domain
KUC3_37340	COG3706	GGDEF domain
KUC3_37340	COG4251	negative regulation of phosphorylation
KUC3_37340	COG5001	Diguanylate cyclase
KUC3_37360	COG4191	Histidine kinase
KUC3_37370	COG2204	response regulator
KUC3_37380	COG0577	efflux transmembrane transporter activity
KUC3_37380	COG1136	(ABC) transporter
KUC3_37390	COG1136	(ABC) transporter
KUC3_37390	COG0577	efflux transmembrane transporter activity
KUC3_37410	COG5002	protein histidine kinase activity
KUC3_37410	COG5001	Diguanylate cyclase
KUC3_37430	COG0010	Belongs to the arginase family
KUC3_37440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KUC3_37460	COG0673	inositol 2-dehydrogenase activity
KUC3_37530	COG1166	arginine decarboxylase activity
KUC3_37550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KUC3_37710	COG5001	Diguanylate cyclase
KUC3_37720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUC3_37730	COG1695	Transcriptional regulator
KUC3_37850	COG0328	RNA-DNA hybrid ribonuclease activity
KUC3_37900	COG3030	protein affecting phage T7 exclusion by the F plasmid
KUC3_37910	COG1324	tolerance protein
KUC3_37920	COG4232	protein-disulfide reductase activity
KUC3_37930	COG0739	heme binding
KUC3_37940	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KUC3_37950	COG0511	ligase activity, forming carbon-carbon bonds
KUC3_37960	COG0439	Biotin carboxylase
KUC3_38060	COG0154	amidase activity
KUC3_38090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUC3_38100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KUC3_38130	COG0151	Belongs to the GarS family
KUC3_38150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KUC3_38160	COG3954	Phosphoribulokinase
KUC3_38220	COG1501	Belongs to the glycosyl hydrolase 31 family
KUC3_38240	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KUC3_38250	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KUC3_38270	COG3031	protein transport across the cell outer membrane
KUC3_38290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KUC3_38300	COG1459	type II secretion system
KUC3_38310	COG2165	general secretion pathway protein
KUC3_38320	COG2165	general secretion pathway protein
KUC3_38330	COG2165	general secretion pathway protein
KUC3_38340	COG4795	General secretion pathway protein
KUC3_38370	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KUC3_38410	COG1012	belongs to the aldehyde dehydrogenase family
KUC3_38430	COG1011	Hydrolase
KUC3_38440	COG0494	nUDIX hydrolase
KUC3_38450	COG1218	3'(2'),5'-bisphosphate nucleotidase
KUC3_38470	COG2943	transferase activity, transferring hexosyl groups
KUC3_38480	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KUC3_38500	COG3089	Belongs to the UPF0270 family
KUC3_38510	COG0429	hydrolase of the alpha beta-hydrolase fold
KUC3_38530	COG0488	(ABC) transporter
KUC3_38610	COG0545	Peptidyl-prolyl cis-trans isomerase
KUC3_38630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KUC3_38640	COG2183	response to ionizing radiation
KUC3_38670	COG0596	Alpha beta hydrolase
KUC3_38680	COG1040	competence protein
KUC3_38710	COG1794	racemase activity, acting on amino acids and derivatives
KUC3_38740	COG0534	Mate efflux family protein
KUC3_38760	COG1649	PFAM Uncharacterised BCR, COG1649
KUC3_38760	COG0726	polysaccharide deacetylase
KUC3_38780	COG1999	signal sequence binding
KUC3_38790	COG0109	protoheme IX farnesyltransferase activity
KUC3_38800	COG1612	heme a metabolic process
KUC3_38850	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KUC3_38860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KUC3_38870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KUC3_38920	COG0129	dihydroxy-acid dehydratase activity
KUC3_38930	COG2860	membrane
KUC3_38940	COG0606	chelatase, subunit chli
KUC3_38950	COG0583	DNA-binding transcription factor activity
KUC3_39050	COG2814	Major facilitator Superfamily
KUC3_39060	COG1073	alpha beta
KUC3_39070	COG0729	surface antigen
KUC3_39080	COG2911	Protein conserved in bacteria
KUC3_39100	COG1595	DNA-templated transcription, initiation
KUC3_39130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KUC3_39150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KUC3_39190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KUC3_39240	COG1228	amidohydrolase
KUC3_39290	COG0425	Belongs to the sulfur carrier protein TusA family
KUC3_39320	COG1561	YicC-like family, N-terminal region
KUC3_39380	COG0270	DNA (cytosine-5-)-methyltransferase activity
KUC3_39440	COG0644	oxidoreductase
KUC3_39530	COG2211	Major facilitator Superfamily
KUC3_39540	COG1609	Transcriptional regulator
KUC3_39570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KUC3_39570	COG2199	diguanylate cyclase activity
KUC3_39580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KUC3_39620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KUC3_39660	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KUC3_39670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KUC3_39710	COG1475	DNA binding
KUC3_39720	COG1192	Involved in chromosome partitioning
KUC3_39750	COG0488	(ABC) transporter
KUC3_39780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KUC3_39790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KUC3_39860	COG0706	membrane insertase activity
KUC3_39870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KUC3_39880	COG0594	ribonuclease P activity