locus-tag	class	description
NLG07_00050	COG0189	ligase activity
NLG07_00060	COG0189	ligase activity
NLG07_00060	COG4067	protein conserved in archaea
NLG07_00075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NLG07_00075	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NLG07_00090	COG1560	Kdo2-lipid A biosynthetic process
NLG07_00095	COG2205	protein histidine kinase activity
NLG07_00095	COG3437	response regulator, receiver
NLG07_00095	COG3850	Histidine kinase
NLG07_00095	COG4999	Histidine kinase
NLG07_00130	COG0385	Bile acid
NLG07_00140	COG0729	surface antigen
NLG07_00145	COG2911	Protein conserved in bacteria
NLG07_00160	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NLG07_00170	COG0488	(ABC) transporter
NLG07_00175	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NLG07_00175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NLG07_00185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NLG07_00190	COG0583	DNA-binding transcription factor activity
NLG07_00200	COG0123	including yeast histone deacetylase and acetoin utilization protein
NLG07_00235	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NLG07_00245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NLG07_00255	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NLG07_00260	COG0784	Response regulator, receiver
NLG07_00260	COG2198	Histidine kinase
NLG07_00260	COG5002	protein histidine kinase activity
NLG07_00265	COG0067	glutamate synthase
NLG07_00265	COG0070	glutamate synthase
NLG07_00265	COG0069	glutamate synthase activity
NLG07_00270	COG0493	'glutamate synthase
NLG07_00275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLG07_00285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLG07_00325	COG1981	membrane
NLG07_00330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NLG07_00340	COG1217	gtp-binding protein TYPA
NLG07_00345	COG0174	glutamine synthetase
NLG07_00350	COG3852	Histidine kinase
NLG07_00360	COG0204	Acyl-transferase
NLG07_00370	COG0525	valine-tRNA ligase activity
NLG07_00375	COG2927	DNA polymerase III (CHI subunit)
NLG07_00380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NLG07_00385	COG0795	lipopolysaccharide-transporting ATPase activity
NLG07_00390	COG0795	lipopolysaccharide-transporting ATPase activity
NLG07_00415	COG2828	Protein conserved in bacteria
NLG07_00420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NLG07_00425	COG0372	Belongs to the citrate synthase family
NLG07_00430	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NLG07_00450	COG1227	inorganic diphosphatase activity
NLG07_00470	COG0582	viral genome integration into host DNA
NLG07_00550	COG0745	RESPONSE REGULATOR receiver
NLG07_00555	COG3850	Histidine kinase
NLG07_00555	COG5002	protein histidine kinase activity
NLG07_00590	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NLG07_00600	COG1063	alcohol dehydrogenase
NLG07_00625	COG0798	PFAM Bile acid sodium symporter
NLG07_00640	COG3634	alkyl hydroperoxide reductase activity
NLG07_00645	COG0450	alkyl hydroperoxide reductase
NLG07_00680	COG0823	Involved in the tonB-independent uptake of proteins
NLG07_00680	COG1506	peptidase
NLG07_00680	COG4946	Tricorn protease homolog
NLG07_00765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NLG07_00790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLG07_00810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NLG07_00815	COG0204	Acyl-transferase
NLG07_00820	COG0668	transmembrane transport
NLG07_00835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NLG07_00840	COG0733	neurotransmitter:sodium symporter activity
NLG07_00860	COG2239	Acts as a magnesium transporter
NLG07_00885	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NLG07_00890	COG1137	ATPase activity
NLG07_00905	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NLG07_00910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NLG07_00910	COG0517	IMP dehydrogenase activity
NLG07_00920	COG1127	ABC transporter
NLG07_00925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NLG07_00930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NLG07_00935	COG2854	intermembrane phospholipid transfer
NLG07_00945	COG5007	Belongs to the BolA IbaG family
NLG07_00975	COG0848	biopolymer transport protein
NLG07_00990	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NLG07_01010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NLG07_01015	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NLG07_01020	COG4989	oxidoreductase activity
NLG07_01025	COG0463	Glycosyl transferase, family 2
NLG07_01030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLG07_01040	COG1477	protein flavinylation
NLG07_01045	COG2871	sodium ion transport
NLG07_01050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NLG07_01055	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NLG07_01060	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NLG07_01065	COG1805	sodium ion transport
NLG07_01070	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NLG07_01075	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NLG07_01080	COG0545	Peptidyl-prolyl cis-trans isomerase
NLG07_01085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NLG07_01090	COG0039	L-malate dehydrogenase activity
NLG07_01095	COG1438	arginine binding
NLG07_01105	COG0625	glutathione transferase activity
NLG07_01115	COG0572	uridine kinase
NLG07_01120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NLG07_01135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NLG07_01140	COG4771	TonB-dependent receptor
NLG07_01145	COG0457	Tetratricopeptide repeat
NLG07_01170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NLG07_01175	COG0667	Aldo Keto reductase
NLG07_01180	COG0123	including yeast histone deacetylase and acetoin utilization protein
NLG07_01185	COG0427	acetyl-CoA hydrolase
NLG07_01190	COG1132	(ABC) transporter
NLG07_01225	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NLG07_01235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NLG07_01250	COG0202	RNA polymerase activity
NLG07_01275	COG0201	protein transport
NLG07_01280	COG0200	Binds to the 23S rRNA
NLG07_01290	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLG07_01295	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLG07_01300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLG07_01340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLG07_01345	COG0557	exoribonuclease II activity
NLG07_01360	COG1278	Cold shock
NLG07_01370	COG0028	Belongs to the TPP enzyme family
NLG07_01380	COG0457	Tetratricopeptide repeat
NLG07_01390	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NLG07_01395	COG1162	GTPase activity
NLG07_01420	COG4942	peptidase
NLG07_01425	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLG07_01430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLG07_01435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NLG07_01440	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NLG07_01445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NLG07_01450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NLG07_01455	COG2267	carboxylic ester hydrolase activity
NLG07_01460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NLG07_01470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLG07_01475	COG0137	argininosuccinate synthase activity
NLG07_01485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NLG07_01485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NLG07_01490	COG0281	malic enzyme
NLG07_01495	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NLG07_01535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NLG07_01545	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NLG07_01565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NLG07_01570	COG0180	Tryptophanyl-tRNA synthetase
NLG07_01580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NLG07_01590	COG1012	belongs to the aldehyde dehydrogenase family
NLG07_01610	COG4999	Histidine kinase
NLG07_01610	COG3850	Histidine kinase
NLG07_01610	COG3437	response regulator, receiver
NLG07_01610	COG2205	protein histidine kinase activity
NLG07_01625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLG07_01630	COG1309	transcriptional regulator
NLG07_01635	COG0540	Belongs to the ATCase OTCase family
NLG07_01645	COG2837	iron assimilation
NLG07_01650	COG0405	Gamma-glutamyltransferase
NLG07_01655	COG4946	Tricorn protease homolog
NLG07_01655	COG1506	peptidase
NLG07_01655	COG0823	Involved in the tonB-independent uptake of proteins
NLG07_01660	COG2197	response regulator
NLG07_01670	COG0004	ammonium transporteR
NLG07_01685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NLG07_01690	COG3243	poly(R)-hydroxyalkanoic acid synthase
NLG07_01695	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
NLG07_01715	COG2951	lytic endotransglycosylase activity
NLG07_01720	COG1028	Short-chain dehydrogenase reductase Sdr
NLG07_01730	COG0788	formyltetrahydrofolate deformylase activity
NLG07_01735	COG0339	signal peptide processing
NLG07_01740	COG0300	oxidoreductase activity
NLG07_01745	COG1519	Transferase
NLG07_01775	COG1368	sulfuric ester hydrolase activity
NLG07_01785	COG2194	sulfuric ester hydrolase activity
NLG07_01800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NLG07_01805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NLG07_01825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLG07_01840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLG07_01850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLG07_01860	COG0089	rRNA binding
NLG07_01890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLG07_01895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLG07_01915	COG0346	lactoylglutathione lyase activity
NLG07_01920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NLG07_01945	COG0625	glutathione transferase activity
NLG07_01950	COG4774	siderophore transport
NLG07_01955	COG0110	maltose O-acetyltransferase activity
NLG07_01970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLG07_01980	COG1609	Transcriptional regulator
NLG07_01995	COG1472	Belongs to the glycosyl hydrolase 3 family
NLG07_02010	COG4628	conserved protein (DUF2132)
NLG07_02020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLG07_02025	COG4335	DNA alkylation repair
NLG07_02040	COG1803	Methylglyoxal synthase
NLG07_02050	COG1349	DNA-binding transcription factor activity
NLG07_02075	COG0745	RESPONSE REGULATOR receiver
NLG07_02080	COG1032	radical SAM domain protein
NLG07_02090	COG2198	Histidine kinase
NLG07_02090	COG0784	Response regulator, receiver
NLG07_02090	COG5002	protein histidine kinase activity
NLG07_02120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NLG07_02125	COG1349	DNA-binding transcription factor activity
NLG07_02130	COG2226	methyltransferase
NLG07_02135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLG07_02145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLG07_02150	COG1166	arginine decarboxylase activity
NLG07_02165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NLG07_02170	COG3030	protein affecting phage T7 exclusion by the F plasmid
NLG07_02175	COG4232	protein-disulfide reductase activity
NLG07_02185	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NLG07_02190	COG0511	ligase activity, forming carbon-carbon bonds
NLG07_02195	COG0439	Biotin carboxylase
NLG07_02225	COG0583	DNA-binding transcription factor activity
NLG07_02240	COG4774	siderophore transport
NLG07_02295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLG07_02300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NLG07_02310	COG0151	Belongs to the GarS family
NLG07_02315	COG3954	Phosphoribulokinase
NLG07_02330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLG07_02335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NLG07_02340	COG3031	protein transport across the cell outer membrane
NLG07_02350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NLG07_02355	COG1459	type II secretion system
NLG07_02370	COG2165	general secretion pathway protein
NLG07_02390	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NLG07_02400	COG4251	negative regulation of phosphorylation
NLG07_02400	COG3706	GGDEF domain
NLG07_02400	COG2203	Gaf domain
NLG07_02400	COG5001	Diguanylate cyclase
NLG07_02405	COG1011	Hydrolase
NLG07_02410	COG0494	nUDIX hydrolase
NLG07_02415	COG1218	3'(2'),5'-bisphosphate nucleotidase
NLG07_02420	COG3089	Belongs to the UPF0270 family
NLG07_02425	COG0429	hydrolase of the alpha beta-hydrolase fold
NLG07_02435	COG0488	(ABC) transporter
NLG07_02440	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NLG07_02455	COG2827	Endonuclease containing a URI domain
NLG07_02460	COG0545	Peptidyl-prolyl cis-trans isomerase
NLG07_02475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NLG07_02485	COG2183	response to ionizing radiation
NLG07_02495	COG1040	competence protein
NLG07_02510	COG0534	Mate efflux family protein
NLG07_02515	COG0385	Bile acid
NLG07_02525	COG1999	signal sequence binding
NLG07_02530	COG0109	protoheme IX farnesyltransferase activity
NLG07_02535	COG1612	heme a metabolic process
NLG07_02560	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NLG07_02570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NLG07_02575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLG07_02595	COG0129	dihydroxy-acid dehydratase activity
NLG07_02605	COG0606	chelatase, subunit chli
NLG07_02615	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NLG07_02620	COG2814	Major facilitator Superfamily
NLG07_02630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLG07_02635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLG07_02650	COG1012	belongs to the aldehyde dehydrogenase family
NLG07_02670	COG0402	S-adenosylhomocysteine deaminase activity
NLG07_02685	COG0425	Belongs to the sulfur carrier protein TusA family
NLG07_02690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLG07_02700	COG1561	YicC-like family, N-terminal region
NLG07_02760	COG0789	Transcriptional regulator
NLG07_02785	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NLG07_02830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLG07_02845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NLG07_02845	COG2010	Cytochrome c
NLG07_02850	COG0789	Transcriptional regulator
NLG07_02855	COG2217	Heavy metal translocating P-type atpase
NLG07_02890	COG2205	protein histidine kinase activity
NLG07_02905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NLG07_02910	COG1794	racemase activity, acting on amino acids and derivatives
NLG07_02915	COG1473	amidohydrolase
NLG07_02930	COG2365	Tyrosine phosphatase family
NLG07_02935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NLG07_02955	COG1116	anion transmembrane transporter activity
NLG07_02955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NLG07_02960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NLG07_02965	COG1116	anion transmembrane transporter activity
NLG07_02980	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NLG07_02985	COG0521	Mo-molybdopterin cofactor biosynthetic process
NLG07_02990	COG0315	cyclic pyranopterin monophosphate synthase activity
NLG07_02995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NLG07_03000	COG0314	molybdopterin synthase activity
NLG07_03005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLG07_03010	COG0243	molybdopterin cofactor binding
NLG07_03015	COG3707	response regulator
NLG07_03020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NLG07_03025	COG0746	molybdenum cofactor guanylyltransferase activity
NLG07_03035	COG0303	'Molybdopterin
NLG07_03040	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NLG07_03050	COG0589	response to stress
NLG07_03065	COG0584	glycerophosphoryl diester phosphodiesterase
NLG07_03075	COG3122	Protein conserved in bacteria
NLG07_03080	COG0778	Nitroreductase
NLG07_03115	COG0419	ATPase involved in DNA repair
NLG07_03160	COG1643	Atp-dependent helicase
NLG07_03165	COG4585	Histidine kinase
NLG07_03170	COG2197	response regulator
NLG07_03180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NLG07_03200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLG07_03205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLG07_03225	COG1475	DNA binding
NLG07_03230	COG1192	Involved in chromosome partitioning
NLG07_03255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NLG07_03260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLG07_03265	COG1666	GTP binding
NLG07_03270	COG0706	membrane insertase activity
NLG07_03275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NLG07_03280	COG0594	ribonuclease P activity
NLG07_03285	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NLG07_03300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLG07_03305	COG0187	DNA topoisomerase II activity
NLG07_03335	COG3078	GTPase activator activity
NLG07_03355	COG1280	lysine exporter protein (LysE YggA)
NLG07_03360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLG07_03360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLG07_03365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NLG07_03370	COG0569	domain protein
NLG07_03375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLG07_03375	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLG07_03380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLG07_03395	COG0758	DNA mediated transformation
NLG07_03400	COG2922	Belongs to the Smg family
NLG07_03405	COG0551	DNA topoisomerase type I activity
NLG07_03410	COG0009	L-threonylcarbamoyladenylate synthase
NLG07_03415	COG0408	coproporphyrinogen oxidase activity
NLG07_03420	COG3047	cAMP biosynthetic process
NLG07_03425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLG07_03430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NLG07_03475	COG1082	Xylose isomerase domain protein TIM barrel
NLG07_03495	COG2819	hydrolase of the alpha beta superfamily
NLG07_03520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NLG07_03525	COG2003	Belongs to the UPF0758 family
NLG07_03530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NLG07_03540	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NLG07_03550	COG3642	lipopolysaccharide core region biosynthetic process
NLG07_03555	COG0859	PFAM glycosyl transferase family 9
NLG07_03565	COG0156	8-amino-7-oxononanoate synthase activity
NLG07_03575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLG07_03585	COG3161	chorismate lyase activity
NLG07_03590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NLG07_03595	COG2960	long-chain fatty acid transporting porin activity
NLG07_03600	COG0210	DNA helicase
NLG07_03605	COG0778	Nitroreductase
NLG07_03610	COG3071	HemY protein
NLG07_03615	COG2959	enzyme of heme biosynthesis
NLG07_03625	COG0181	hydroxymethylbilane synthase activity
NLG07_03630	COG0400	carboxylic ester hydrolase activity
NLG07_03635	COG1965	Belongs to the frataxin family
NLG07_03650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLG07_03660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLG07_03665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLG07_03670	COG0742	ribosomal rna small subunit methyltransferase
NLG07_03675	COG0312	modulator of DNA gyrase
NLG07_03680	COG3028	Belongs to the UPF0307 family
NLG07_03685	COG0312	modulator of DNA gyrase
NLG07_03695	COG3164	Protein of unknown function
NLG07_03710	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NLG07_03715	COG1792	Involved in formation and maintenance of cell shape
NLG07_03720	COG1077	Cell shape determining protein MreB Mrl
NLG07_03730	COG2814	Major facilitator Superfamily
NLG07_03735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NLG07_03745	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NLG07_03750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NLG07_03755	COG0163	prenyltransferase activity
NLG07_03780	COG0019	diaminopimelate decarboxylase activity
NLG07_03785	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLG07_03795	COG1011	Hydrolase
NLG07_03800	COG0210	DNA helicase
NLG07_03815	COG2962	Rard protein
NLG07_03820	COG0514	ATP-dependent DNA helicase (RecQ)
NLG07_03830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NLG07_03835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NLG07_03845	COG0004	ammonium transporteR
NLG07_03850	COG2081	HI0933 family
NLG07_03855	COG0745	RESPONSE REGULATOR receiver
NLG07_03860	COG0297	glycogen (starch) synthase activity
NLG07_03865	COG2813	Specifically methylates the guanine in position
NLG07_03870	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NLG07_03880	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NLG07_03915	COG1309	transcriptional regulator
NLG07_03970	COG1368	sulfuric ester hydrolase activity
NLG07_03980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NLG07_03985	COG2194	sulfuric ester hydrolase activity
NLG07_04015	COG3292	Two component regulator propeller
NLG07_04015	COG0745	RESPONSE REGULATOR receiver
NLG07_04015	COG3292	Two component regulator propeller
NLG07_04015	COG2205	protein histidine kinase activity
NLG07_04015	COG2205	protein histidine kinase activity
NLG07_04015	COG0745	RESPONSE REGULATOR receiver
NLG07_04050	COG0305	Participates in initiation and elongation during chromosome replication
NLG07_04060	COG0735	belongs to the Fur family
NLG07_04070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NLG07_04080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NLG07_04080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLG07_04085	COG0802	atpase or kinase
NLG07_04095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLG07_04100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLG07_04105	COG1923	regulation of RNA biosynthetic process
NLG07_04110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLG07_04115	COG0330	HflC and HflK could
NLG07_04120	COG0330	HflC and HflK could
NLG07_04125	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NLG07_04130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NLG07_04150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NLG07_04165	COG1793	dna ligase
NLG07_04175	COG2211	Major facilitator Superfamily
NLG07_04180	COG0366	Alpha amylase catalytic
NLG07_04195	COG1201	RNA secondary structure unwinding
NLG07_04200	COG1823	symporter activity
NLG07_04210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NLG07_04215	COG2957	Belongs to the agmatine deiminase family
NLG07_04225	COG0302	gtp cyclohydrolase
NLG07_04230	COG3040	lipid binding
NLG07_04245	COG0418	dihydroorotase activity
NLG07_04250	COG0513	Belongs to the DEAD box helicase family
NLG07_04260	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NLG07_04265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NLG07_04270	COG1132	(ABC) transporter
NLG07_04280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NLG07_04290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLG07_04295	COG0081	regulation of translation
NLG07_04300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLG07_04305	COG0222	ribosome binding
NLG07_04310	COG0085	RNA polymerase activity
NLG07_04315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLG07_04330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLG07_04335	COG0049	tRNA binding
NLG07_04340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLG07_04360	COG1253	flavin adenine dinucleotide binding
NLG07_04375	COG1131	(ABC) transporter
NLG07_04380	COG0842	Transport permease protein
NLG07_04385	COG4106	trans-aconitate 2-methyltransferase activity
NLG07_04390	COG0076	glutamate decarboxylase activity
NLG07_04395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NLG07_04405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NLG07_04415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLG07_04420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NLG07_04430	COG2095	MarC family integral membrane protein
NLG07_04440	COG0742	ribosomal rna small subunit methyltransferase
NLG07_04450	COG2884	Cell division ATP-binding protein ftsE
NLG07_04455	COG2177	Part of the ABC transporter FtsEX involved in
NLG07_04465	COG0456	acetyltransferase
NLG07_04490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NLG07_04500	COG0281	malic enzyme
NLG07_04510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLG07_04515	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NLG07_04520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NLG07_04535	COG1609	Transcriptional regulator
NLG07_04545	COG1228	amidohydrolase
NLG07_04550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLG07_04560	COG0339	signal peptide processing
NLG07_04570	COG2226	methyltransferase
NLG07_04590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLG07_04595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLG07_04600	COG0805	protein transport
NLG07_04615	COG0248	Ppx GppA phosphatase
NLG07_04620	COG0513	Belongs to the DEAD box helicase family
NLG07_04625	COG3118	belongs to the thioredoxin family
NLG07_04640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLG07_04645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLG07_04655	COG2133	pyrroloquinoline quinone binding
NLG07_04660	COG0564	pseudouridine synthase activity
NLG07_04665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NLG07_04670	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NLG07_04680	COG3118	belongs to the thioredoxin family
NLG07_04705	COG3876	Protein conserved in bacteria
NLG07_04710	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NLG07_04720	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NLG07_04720	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NLG07_04720	COG0506	proline dehydrogenase activity
NLG07_04725	COG3025	triphosphatase activity
NLG07_04745	COG0494	nUDIX hydrolase
NLG07_04755	COG0730	response to heat
NLG07_04760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLG07_04765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLG07_04775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NLG07_04780	COG1741	Belongs to the pirin family
NLG07_04790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NLG07_04790	COG1648	precorrin-2 dehydrogenase activity
NLG07_04795	COG0513	Belongs to the DEAD box helicase family
NLG07_04805	COG1538	Outer membrane efflux protein
NLG07_04810	COG0494	nUDIX hydrolase
NLG07_04820	COG3150	esterase
NLG07_04840	COG1509	lysine 2,3-aminomutase activity
NLG07_04845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLG07_04850	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NLG07_04870	COG2813	Specifically methylates the guanine in position
NLG07_04880	COG0271	Belongs to the BolA IbaG family
NLG07_04885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NLG07_04895	COG1238	metal cluster binding
NLG07_04905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NLG07_04910	COG0585	pseudouridine synthase activity
NLG07_04915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NLG07_04920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NLG07_04925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NLG07_04935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLG07_04940	COG0183	Belongs to the thiolase family
NLG07_04945	COG1024	Enoyl-CoA hydratase
NLG07_04945	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLG07_04950	COG0006	proline dipeptidase activity
NLG07_04955	COG0142	geranyltranstransferase activity
NLG07_04970	COG0678	peroxiredoxin activity
NLG07_04970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NLG07_04990	COG0501	Belongs to the peptidase M48B family
NLG07_04995	COG4269	membrane
NLG07_05005	COG0659	secondary active sulfate transmembrane transporter activity
NLG07_05025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NLG07_05030	COG4206	TonB-dependent receptor
NLG07_05035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NLG07_05050	COG1960	acyl-CoA dehydrogenase activity
NLG07_05060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLG07_05065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NLG07_05075	COG0358	DNA primase activity
NLG07_05095	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NLG07_05100	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLG07_05110	COG1968	undecaprenyl-diphosphatase activity
NLG07_05115	COG0537	adenosine 5'-monophosphoramidase activity
NLG07_05120	COG2974	May be involved in recombination
NLG07_05125	COG0745	RESPONSE REGULATOR receiver
NLG07_05130	COG5002	protein histidine kinase activity
NLG07_05155	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NLG07_05160	COG1739	Uncharacterized protein family UPF0029
NLG07_05180	COG1049	propionate catabolic process, 2-methylcitrate cycle
NLG07_05185	COG0500	methyltransferase
NLG07_05190	COG1505	serine-type exopeptidase activity
NLG07_05195	COG2326	polyphosphate kinase activity
NLG07_05205	COG0811	peptide transport
NLG07_05210	COG0811	peptide transport
NLG07_05215	COG0848	biopolymer transport protein
NLG07_05220	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NLG07_05240	COG2133	pyrroloquinoline quinone binding
NLG07_05250	COG0527	aspartate kinase activity
NLG07_05260	COG2967	ApaG domain
NLG07_05270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NLG07_05275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NLG07_05280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NLG07_05285	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NLG07_05290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NLG07_05295	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NLG07_05305	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NLG07_05320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLG07_05325	COG3956	TIGRFAM MazG family protein
NLG07_05335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NLG07_05340	COG0723	plastoquinol--plastocyanin reductase activity
NLG07_05345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NLG07_05350	COG2857	Cytochrome c1
NLG07_05355	COG0625	glutathione transferase activity
NLG07_05360	COG2969	positive regulation of protein catabolic process
NLG07_05365	COG2823	Periplasmic or secreted lipoprotein
NLG07_05375	COG0792	nuclease activity
NLG07_05385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLG07_05410	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NLG07_05425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NLG07_05435	COG1192	Involved in chromosome partitioning
NLG07_05440	COG1671	Belongs to the UPF0178 family
NLG07_05455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NLG07_05465	COG0083	homoserine kinase activity
NLG07_05470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NLG07_05490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLG07_05510	COG0762	integral membrane protein
NLG07_05515	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLG07_05520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NLG07_05535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLG07_05540	COG1678	Uncharacterized ACR, COG1678
NLG07_05550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NLG07_05555	COG0668	transmembrane transport
NLG07_05560	COG0501	Belongs to the peptidase M48B family
NLG07_05565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLG07_05570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLG07_05580	COG0126	phosphoglycerate kinase activity
NLG07_05585	COG3588	fructose-bisphosphate aldolase
NLG07_05595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NLG07_05600	COG0573	inorganic phosphate transmembrane transporter activity
NLG07_05605	COG0581	inorganic phosphate transmembrane transporter activity
NLG07_05610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NLG07_05620	COG0306	phosphate transporter
NLG07_05625	COG0583	DNA-binding transcription factor activity
NLG07_05640	COG4191	Histidine kinase
NLG07_05645	COG2204	response regulator
NLG07_05665	COG2001	Belongs to the MraZ family
NLG07_05675	COG3116	cell division
NLG07_05680	COG0768	penicillin binding
NLG07_05685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NLG07_05690	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLG07_05695	COG0772	Belongs to the SEDS family
NLG07_05700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLG07_05705	COG1181	Belongs to the D-alanine--D-alanine ligase family
NLG07_05710	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NLG07_05715	COG0849	cell division
NLG07_05720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLG07_05725	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NLG07_05730	COG0739	heme binding
NLG07_05740	COG0494	nUDIX hydrolase
NLG07_05745	COG2988	succinylglutamate desuccinylase activity
NLG07_05750	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NLG07_05760	COG0237	dephospho-CoA kinase activity
NLG07_05765	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NLG07_05770	COG1459	type II secretion system
NLG07_05790	COG3023	N-Acetylmuramoyl-L-alanine amidase
NLG07_05810	COG0508	dehydrogenase complex catalyzes the overall conversion of
NLG07_05815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLG07_05820	COG3313	Fe-S protein
NLG07_05830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NLG07_05835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLG07_05850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLG07_05860	COG3079	Belongs to the UPF0149 family
NLG07_05865	COG0006	proline dipeptidase activity
NLG07_05870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NLG07_05875	COG3409	Peptidoglycan-binding domain 1 protein
NLG07_05875	COG3267	Type II secretory pathway component ExeA
NLG07_05885	COG0489	protein tyrosine kinase activity
NLG07_05900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NLG07_05905	COG0726	polysaccharide deacetylase
NLG07_05915	COG0438	transferase activity, transferring glycosyl groups
NLG07_05935	COG0438	transferase activity, transferring glycosyl groups
NLG07_05950	COG2244	polysaccharide biosynthetic process
NLG07_05960	COG0438	transferase activity, transferring glycosyl groups
NLG07_05965	COG0367	asparagine synthase
NLG07_06070	COG1785	Belongs to the alkaline phosphatase family
NLG07_06080	COG0754	glutathionylspermidine amidase activity
NLG07_06085	COG5463	Belongs to the UPF0441 family
NLG07_06090	COG3766	membrane
NLG07_06105	COG0343	queuine tRNA-ribosyltransferase activity
NLG07_06110	COG1862	Preprotein translocase
NLG07_06115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NLG07_06120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NLG07_06130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NLG07_06135	COG1045	serine acetyltransferase
NLG07_06140	COG1959	2 iron, 2 sulfur cluster binding
NLG07_06145	COG1104	cysteine desulfurase activity
NLG07_06150	COG0822	iron-sulfur transferase activity
NLG07_06155	COG0316	Belongs to the HesB IscA family
NLG07_06160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NLG07_06165	COG0443	Heat shock 70 kDa protein
NLG07_06170	COG0633	Ferredoxin
NLG07_06180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NLG07_06185	COG1388	LysM domain
NLG07_06185	COG3103	Sh3 type 3 domain protein
NLG07_06185	COG0791	NLP P60 protein
NLG07_06190	COG1426	Protein conserved in bacteria
NLG07_06200	COG0124	histidyl-tRNA synthetase
NLG07_06205	COG2976	Protein conserved in bacteria
NLG07_06210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NLG07_06220	COG1570	exodeoxyribonuclease VII activity
NLG07_06225	COG0516	GMP reductase activity
NLG07_06225	COG0517	IMP dehydrogenase activity
NLG07_06230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NLG07_06230	COG0519	Catalyzes the synthesis of GMP from XMP
NLG07_06240	COG0442	prolyl-tRNA aminoacylation
NLG07_06245	COG1720	tRNA m6t6A37 methyltransferase activity
NLG07_06315	COG0544	peptidyl-prolyl cis-trans isomerase activity
NLG07_06320	COG0740	serine-type endopeptidase activity
NLG07_06325	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLG07_06330	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NLG07_06340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NLG07_06350	COG1283	sodium-dependent phosphate transmembrane transporter activity
NLG07_06355	COG2234	aminopeptidase activity
NLG07_06360	COG0268	Binds directly to 16S ribosomal RNA
NLG07_06365	COG0728	peptidoglycan biosynthetic process
NLG07_06370	COG0196	riboflavin kinase activity
NLG07_06375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLG07_06385	COG1047	Peptidyl-prolyl cis-trans
NLG07_06390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NLG07_06435	COG1047	Peptidyl-prolyl cis-trans
NLG07_06445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NLG07_06455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NLG07_06460	COG1595	DNA-templated transcription, initiation
NLG07_06470	COG3026	antisigma factor binding
NLG07_06490	COG0571	ribonuclease III activity
NLG07_06495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLG07_06505	COG0084	hydrolase, TatD family'
NLG07_06515	COG0560	Phosphoserine phosphatase
NLG07_06520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLG07_06525	COG1278	Cold shock
NLG07_06530	COG0488	(ABC) transporter
NLG07_06545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLG07_06550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NLG07_06550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NLG07_06565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NLG07_06580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NLG07_06585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLG07_06590	COG0142	geranyltranstransferase activity
NLG07_06600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NLG07_06615	COG4221	oxidoreductase activity
NLG07_06630	COG1595	DNA-templated transcription, initiation
NLG07_06635	COG3806	Anti-sigma factor
NLG07_06645	COG0564	pseudouridine synthase activity
NLG07_06650	COG0542	response to heat
NLG07_06655	COG1183	phosphatidylcholine synthase activity
NLG07_06675	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NLG07_06680	COG3630	sodium ion export across plasma membrane
NLG07_06690	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NLG07_06695	COG4172	Belongs to the ABC transporter superfamily
NLG07_06705	COG4171	peptide transport system, permease
NLG07_06710	COG4168	peptide transport system, permease
NLG07_06715	COG0747	negative chemotaxis
NLG07_06720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NLG07_06725	COG1842	Phage shock protein A
NLG07_06735	COG1983	PspC domain protein
NLG07_06745	COG0625	glutathione transferase activity
NLG07_06750	COG1522	sequence-specific DNA binding
NLG07_06785	COG0811	peptide transport
NLG07_06790	COG0811	peptide transport
NLG07_06795	COG0848	biopolymer transport protein
NLG07_06815	COG0642	Histidine kinase
NLG07_06845	COG0121	glutamine amidotransferase
NLG07_06860	COG4948	Mandelate Racemase Muconate Lactonizing
NLG07_06870	COG2153	protein acetylation
NLG07_06880	COG1366	Belongs to the anti-sigma-factor antagonist family
NLG07_06900	COG0745	RESPONSE REGULATOR receiver
NLG07_06905	COG1215	transferase activity, transferring glycosyl groups
NLG07_06910	COG0438	transferase activity, transferring glycosyl groups
NLG07_06955	COG0438	transferase activity, transferring glycosyl groups
NLG07_06965	COG0604	alcohol dehydrogenase
NLG07_06995	COG2824	Alkylphosphonate utilization operon protein PhnA
NLG07_07010	COG0431	NADPH-dependent FMN reductase
NLG07_07020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NLG07_07025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLG07_07030	COG0564	pseudouridine synthase activity
NLG07_07040	COG2918	glutathione biosynthetic process
NLG07_07055	COG2840	Smr protein MutS2
NLG07_07060	COG2890	protein-(glutamine-N5) methyltransferase activity
NLG07_07070	COG2719	SpoVR family
NLG07_07080	COG2766	serine protein kinase
NLG07_07085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NLG07_07090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NLG07_07095	COG2906	2 iron, 2 sulfur cluster binding
NLG07_07100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NLG07_07105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLG07_07110	COG4660	Part of a membrane complex involved in electron transport
NLG07_07115	COG4659	FMN binding
NLG07_07120	COG4658	electron transport chain
NLG07_07125	COG4656	Part of a membrane complex involved in electron transport
NLG07_07130	COG2878	Part of a membrane complex involved in electron transport
NLG07_07135	COG4657	Part of a membrane complex involved in electron transport
NLG07_07150	COG0534	Mate efflux family protein
NLG07_07155	COG0556	nucleotide-excision repair
NLG07_07160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NLG07_07165	COG0602	queuosine metabolic process
NLG07_07175	COG0367	asparagine synthase
NLG07_07190	COG4555	ABC transporter
NLG07_07195	COG1668	transmembrane transport
NLG07_07200	COG0730	response to heat
NLG07_07215	COG3273	potassium ion transport
NLG07_07215	COG0471	metal ion transport
NLG07_07230	COG0529	Catalyzes the synthesis of activated sulfate
NLG07_07235	COG0175	sulfate reduction
NLG07_07240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLG07_07275	COG0714	Associated with various cellular activities
NLG07_07285	COG1024	Enoyl-CoA hydratase
NLG07_07285	COG1250	3-hydroxyacyl-CoA dehydrogenase
NLG07_07310	COG4536	flavin adenine dinucleotide binding
NLG07_07320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLG07_07325	COG0228	four-way junction DNA binding
NLG07_07330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLG07_07335	COG0336	Belongs to the RNA methyltransferase TrmD family
NLG07_07340	COG0335	large ribosomal subunit rRNA binding
NLG07_07355	COG1410	methionine synthase
NLG07_07355	COG0646	methionine synthase
NLG07_07360	COG1410	methionine synthase
NLG07_07360	COG0646	methionine synthase
NLG07_07370	COG3590	peptidase
NLG07_07380	COG2137	regulation of response to DNA damage stimulus
NLG07_07385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLG07_07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLG07_07425	COG4191	Histidine kinase
NLG07_07440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLG07_07445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLG07_07455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLG07_07460	COG0326	Molecular chaperone. Has ATPase activity
NLG07_07470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLG07_07505	COG1902	pentaerythritol trinitrate reductase activity
NLG07_07505	COG0446	pyridine nucleotide-disulphide oxidoreductase
NLG07_07515	COG2226	methyltransferase
NLG07_07520	COG0140	phosphoribosyl-ATP diphosphatase activity
NLG07_07520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NLG07_07535	COG3153	acetyltransferase
NLG07_07535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NLG07_07550	COG3123	guanosine phosphorylase activity
NLG07_07555	COG4948	Mandelate Racemase Muconate Lactonizing
NLG07_07570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLG07_07580	COG0017	Asparaginyl-tRNA synthetase
NLG07_07590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NLG07_07595	COG0156	8-amino-7-oxononanoate synthase activity
NLG07_07605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NLG07_07650	COG1294	oxidase, subunit
NLG07_07655	COG4890	Cyd operon protein YbgT
NLG07_07660	COG4988	ABC transporter
NLG07_07665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NLG07_07670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLG07_07675	COG4139	cobalamin transport
NLG07_07685	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NLG07_07690	COG5265	(ABC) transporter
NLG07_07695	COG0640	Transcriptional regulator
NLG07_07710	COG1322	Protein conserved in bacteria
NLG07_07720	COG1596	polysaccharide export
NLG07_07730	COG0489	protein tyrosine kinase activity
NLG07_07730	COG3206	protein involved in exopolysaccharide biosynthesis
NLG07_07755	COG1086	Polysaccharide biosynthesis protein
NLG07_07760	COG1083	cytidylyl-transferase
NLG07_07770	COG2089	acid synthase
NLG07_07790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NLG07_07845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NLG07_07850	COG1051	belongs to the nudix hydrolase family
NLG07_07860	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NLG07_07865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NLG07_07870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLG07_07880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLG07_07970	COG2197	response regulator
NLG07_07985	COG0646	methionine synthase
NLG07_07985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NLG07_07990	COG1523	belongs to the glycosyl hydrolase 13 family
NLG07_07995	COG1501	Belongs to the glycosyl hydrolase 31 family
NLG07_08015	COG1446	asparaginase
NLG07_08020	COG1643	Atp-dependent helicase
NLG07_08030	COG0328	RNA-DNA hybrid ribonuclease activity
NLG07_08035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NLG07_08065	COG0366	Alpha amylase catalytic
NLG07_08070	COG1136	(ABC) transporter
NLG07_08075	COG4591	ABC-type transport system involved in lipoprotein release permease component
NLG07_08080	COG1301	dicarboxylic acid transport
NLG07_08085	COG3724	N-succinylarginine dihydrolase activity
NLG07_08090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLG07_08095	COG1530	ribonuclease E activity
NLG07_08100	COG0564	pseudouridine synthase activity
NLG07_08105	COG0546	phosphoglycolate phosphatase activity
NLG07_08115	COG1399	metal-binding, possibly nucleic acid-binding protein
NLG07_08125	COG0416	fatty acid biosynthetic process
NLG07_08130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLG07_08145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLG07_08150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NLG07_08155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NLG07_08160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLG07_08170	COG0470	DNA polymerase III
NLG07_08175	COG0084	hydrolase, TatD family'
NLG07_08190	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NLG07_08200	COG2205	protein histidine kinase activity
NLG07_08200	COG0784	Response regulator, receiver
NLG07_08205	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NLG07_08210	COG0436	Aminotransferase
NLG07_08220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NLG07_08230	COG3082	Protein of unknown function (DUF1414)
NLG07_08235	COG3081	Nucleoid-associated protein
NLG07_08245	COG1054	Belongs to the UPF0176 family
NLG07_08255	COG0513	Belongs to the DEAD box helicase family
NLG07_08265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NLG07_08270	COG0583	DNA-binding transcription factor activity
NLG07_08275	COG0583	DNA-binding transcription factor activity
NLG07_08280	COG1760	l-serine dehydratase
NLG07_08290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLG07_08305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NLG07_08310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NLG07_08315	COG1984	allophanate hydrolase subunit 2
NLG07_08320	COG0735	belongs to the Fur family
NLG07_08325	COG0716	FMN binding
NLG07_08335	COG0596	Alpha beta hydrolase
NLG07_08380	COG1960	acyl-CoA dehydrogenase activity
NLG07_08385	COG1028	Short-chain dehydrogenase reductase Sdr
NLG07_08390	COG1448	Aminotransferase
NLG07_08425	COG1024	Enoyl-CoA hydratase
NLG07_08450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NLG07_08455	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLG07_08460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLG07_08475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLG07_08480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NLG07_08485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NLG07_08490	COG0539	negative regulation of cytoplasmic translation
NLG07_08495	COG0776	regulation of translation
NLG07_08500	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
NLG07_08505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NLG07_08515	COG0686	Belongs to the AlaDH PNT family
NLG07_08530	COG0531	amino acid
NLG07_08530	COG1674	ftsk spoiiie
NLG07_08535	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NLG07_08540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NLG07_08570	COG0670	Belongs to the BI1 family
NLG07_08580	COG2197	response regulator
NLG07_08585	COG0322	excinuclease ABC activity
NLG07_08615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLG07_08620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NLG07_08625	COG1280	lysine exporter protein (LysE YggA)
NLG07_08645	COG1752	Esterase of the alpha-beta hydrolase superfamily
NLG07_08660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NLG07_08675	COG2217	Heavy metal translocating P-type atpase
NLG07_08685	COG2010	Cytochrome c
NLG07_08700	COG3278	Belongs to the heme-copper respiratory oxidase family
NLG07_08710	COG2193	ferroxidase activity
NLG07_08715	COG2193	ferroxidase activity
NLG07_08720	COG4651	solute:proton antiporter activity
NLG07_08720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NLG07_08730	COG1028	Short-chain dehydrogenase reductase Sdr
NLG07_08750	COG1131	(ABC) transporter
NLG07_08785	COG3901	Regulator of nitric oxide reductase transcription
NLG07_08785	COG0348	domain, Protein
NLG07_08795	COG0784	Response regulator, receiver
NLG07_08795	COG2205	protein histidine kinase activity
NLG07_08855	COG3046	protein related to deoxyribodipyrimidine photolyase
NLG07_08860	COG0415	Belongs to the DNA photolyase family
NLG07_08865	COG0415	Belongs to the DNA photolyase family
NLG07_08870	COG0415	Belongs to the DNA photolyase family
NLG07_08880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NLG07_08885	COG3130	regulation of translation
NLG07_08895	COG0488	(ABC) transporter
NLG07_08910	COG0167	dihydroorotate dehydrogenase activity
NLG07_08915	COG2902	Dehydrogenase
NLG07_08925	COG4447	cellulose binding
NLG07_08940	COG0308	aminopeptidase N
NLG07_08945	COG1757	Na H antiporter
NLG07_08950	COG0733	neurotransmitter:sodium symporter activity
NLG07_08970	COG1956	GAF domain-containing protein
NLG07_08975	COG2715	membrane protein required for spore maturation
NLG07_08980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NLG07_08985	COG1946	Acyl-CoA thioesterase
NLG07_08995	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NLG07_09005	COG0022	dehydrogenase e1 component
NLG07_09010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NLG07_09015	COG0534	Mate efflux family protein
NLG07_09030	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NLG07_09035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLG07_09040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NLG07_09050	COG4783	chaperone-mediated protein folding
NLG07_09090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NLG07_09095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NLG07_09105	COG1960	acyl-CoA dehydrogenase activity
NLG07_09115	COG4106	trans-aconitate 2-methyltransferase activity
NLG07_09120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NLG07_09135	COG1215	transferase activity, transferring glycosyl groups
NLG07_09145	COG2084	Dehydrogenase
NLG07_09150	COG0386	Belongs to the glutathione peroxidase family
NLG07_09155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NLG07_09160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLG07_09170	COG0616	signal peptide processing
NLG07_09175	COG2267	carboxylic ester hydrolase activity
NLG07_09180	COG1028	Short-chain dehydrogenase reductase Sdr
NLG07_09190	COG1609	Transcriptional regulator
NLG07_09195	COG0366	Alpha amylase catalytic
NLG07_09195	COG1874	Beta-galactosidase
NLG07_09200	COG0366	Alpha amylase catalytic
NLG07_09210	COG4191	Histidine kinase
NLG07_09210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NLG07_09215	COG0183	Belongs to the thiolase family
NLG07_09225	COG1960	acyl-CoA dehydrogenase activity
NLG07_09230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NLG07_09240	COG4770	biotin carboxylase activity
NLG07_09280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLG07_09285	COG0708	Exodeoxyribonuclease III
NLG07_09300	COG4591	ABC-type transport system involved in lipoprotein release permease component
NLG07_09305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLG07_09315	COG2096	Adenosyltransferase
NLG07_09320	COG1472	Belongs to the glycosyl hydrolase 3 family
NLG07_09335	COG0776	regulation of translation
NLG07_09340	COG0072	phenylalanine-tRNA ligase activity
NLG07_09355	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NLG07_09360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLG07_09380	COG4585	Histidine kinase
NLG07_09405	COG1393	Belongs to the ArsC family
NLG07_09410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NLG07_09415	COG1876	peptidase activity
NLG07_09430	COG2988	succinylglutamate desuccinylase activity
NLG07_09435	COG0058	SHG alpha-glucan phosphorylase activity
NLG07_09440	COG0033	Phosphoglucomutase
NLG07_09465	COG0583	DNA-binding transcription factor activity
NLG07_09470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NLG07_09480	COG2890	protein-(glutamine-N5) methyltransferase activity
NLG07_09490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NLG07_09500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLG07_09510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLG07_09515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NLG07_09550	COG1115	amino acid carrier protein
NLG07_09565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NLG07_09575	COG1702	phosphate starvation-inducible protein PhoH
NLG07_09580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLG07_09585	COG4535	Mg2 and Co2 transporter CorC
NLG07_09590	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NLG07_09595	COG1228	amidohydrolase
NLG07_09600	COG0659	secondary active sulfate transmembrane transporter activity
NLG07_09605	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NLG07_09610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NLG07_09615	COG0505	Belongs to the CarA family
NLG07_09620	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NLG07_09630	COG3428	Bacterial PH domain
NLG07_09645	COG0484	heat shock protein binding
NLG07_09650	COG0443	Heat shock 70 kDa protein
NLG07_09655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLG07_09660	COG2205	protein histidine kinase activity
NLG07_09670	COG4771	TonB-dependent receptor
NLG07_09675	COG2610	gluconate transmembrane transporter activity
NLG07_09680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NLG07_09690	COG1028	Short-chain dehydrogenase reductase Sdr
NLG07_09695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLG07_09700	COG0497	DNA recombination
NLG07_09705	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NLG07_09715	COG1187	pseudouridine synthase activity
NLG07_09720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLG07_09725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLG07_09740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLG07_09745	COG0512	Glutamine amidotransferase of anthranilate synthase
NLG07_09750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLG07_09755	COG0135	phosphoribosylanthranilate isomerase activity
NLG07_09755	COG0134	indole-3-glycerol-phosphate synthase activity
NLG07_09765	COG0159	tryptophan synthase activity
NLG07_09770	COG2350	Protein conserved in bacteria
NLG07_09775	COG0612	Peptidase, M16
NLG07_09795	COG0628	permease
NLG07_09800	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLG07_09805	COG1090	epimerase
NLG07_09830	COG4181	ATPase activity
NLG07_09855	COG0402	S-adenosylhomocysteine deaminase activity
NLG07_09860	COG0659	secondary active sulfate transmembrane transporter activity
NLG07_09865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLG07_09880	COG4633	Protein conserved in bacteria
NLG07_09895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NLG07_09935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLG07_09950	COG2026	Addiction module toxin, RelE StbE family
NLG07_09970	COG1785	Belongs to the alkaline phosphatase family
NLG07_09975	COG1785	Belongs to the alkaline phosphatase family
NLG07_09985	COG1607	acyl-coa hydrolase
NLG07_09990	COG0513	Belongs to the DEAD box helicase family
NLG07_09995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NLG07_10000	COG1074	ATP-dependent DNA helicase activity
NLG07_10005	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NLG07_10065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NLG07_10065	COG0646	methionine synthase
NLG07_10080	COG2944	sequence-specific DNA binding
NLG07_10085	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
NLG07_10120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLG07_10175	COG2192	nodulation
NLG07_10230	COG0508	dehydrogenase complex catalyzes the overall conversion of
NLG07_10235	COG0567	Dehydrogenase, E1 component
NLG07_10240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NLG07_10250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NLG07_10260	COG0372	Belongs to the citrate synthase family
NLG07_10280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NLG07_10310	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NLG07_10320	COG1663	tetraacyldisaccharide 4'-kinase activity
NLG07_10325	COG1132	(ABC) transporter
NLG07_10340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLG07_10350	COG1196	nuclear chromosome segregation
NLG07_10355	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
NLG07_10370	COG1185	polyribonucleotide nucleotidyltransferase activity
NLG07_10395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NLG07_10400	COG0149	triose-phosphate isomerase activity
NLG07_10405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLG07_10410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NLG07_10420	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NLG07_10425	COG1534	Rna-binding protein
NLG07_10440	COG1067	ATP-dependent peptidase activity
NLG07_10445	COG0495	leucyl-tRNA aminoacylation
NLG07_10450	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
NLG07_10455	COG1466	dna polymerase III delta subunit
NLG07_10465	COG0799	negative regulation of ribosome biogenesis
NLG07_10470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLG07_10475	COG0768	penicillin binding
NLG07_10480	COG0772	Belongs to the SEDS family
NLG07_10495	COG1686	Belongs to the peptidase S11 family
NLG07_10500	COG2921	Belongs to the UPF0250 family
NLG07_10505	COG0321	lipoyl(octanoyl) transferase activity
NLG07_10510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NLG07_10515	COG0252	asparaginase activity
NLG07_10520	COG3139	Protein of unknown function (DUF1315)
NLG07_10530	COG1115	amino acid carrier protein
NLG07_10535	COG2866	Carboxypeptidase
NLG07_10540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NLG07_10560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NLG07_10565	COG1640	4-alpha-glucanotransferase
NLG07_10575	COG0676	glucose-6-phosphate 1-epimerase activity
NLG07_10580	COG0800	Aldolase
NLG07_10590	COG0129	dihydroxy-acid dehydratase activity
NLG07_10600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NLG07_10605	COG1737	Transcriptional regulator
NLG07_10610	COG0469	pyruvate kinase activity
NLG07_10615	COG3268	Saccharopine dehydrogenase
NLG07_10620	COG0778	Nitroreductase
NLG07_10625	COG0616	signal peptide processing
NLG07_10630	COG3092	negative regulation of chromosome organization
NLG07_10635	COG0492	ferredoxin-NADP+ reductase activity
NLG07_10640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NLG07_10645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NLG07_10650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLG07_10655	COG0542	response to heat
NLG07_10660	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NLG07_10665	COG1278	Cold shock
NLG07_10670	COG1187	pseudouridine synthase activity
NLG07_10675	COG0482	sulfurtransferase activity
NLG07_10680	COG2915	High frequency lysogenization protein hflD homolog
NLG07_10685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLG07_10695	COG2850	peptidyl-arginine hydroxylation
NLG07_10705	COG0247	lactate metabolic process
NLG07_10705	COG0277	FAD linked oxidase domain protein
NLG07_10710	COG0574	Belongs to the PEP-utilizing enzyme family
NLG07_10710	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLG07_10720	COG2914	Belongs to the UPF0125 (RnfH) family
NLG07_10725	COG2867	negative regulation of translational initiation
NLG07_10730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NLG07_10735	COG2873	o-acetylhomoserine
NLG07_10750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLG07_10760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLG07_10765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLG07_10770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLG07_10775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLG07_10780	COG0195	Participates in both transcription termination and antitermination
NLG07_10820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NLG07_10835	COG1022	Amp-dependent synthetase and ligase
NLG07_10855	COG4946	Tricorn protease homolog
NLG07_10855	COG0823	Involved in the tonB-independent uptake of proteins
NLG07_10855	COG1506	peptidase
NLG07_10860	COG0183	Belongs to the thiolase family
NLG07_10865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NLG07_10880	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
NLG07_10895	COG0612	Peptidase, M16
NLG07_10915	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NLG07_10930	COG1741	Belongs to the pirin family
NLG07_10935	COG0501	Belongs to the peptidase M48B family
NLG07_10955	COG1136	(ABC) transporter
NLG07_10955	COG0577	efflux transmembrane transporter activity
NLG07_10970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLG07_10970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLG07_10975	COG2226	methyltransferase
NLG07_10980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NLG07_10985	COG1388	LysM domain
NLG07_10985	COG0741	lytic transglycosylase activity
NLG07_10990	COG0215	cysteine-tRNA ligase activity
NLG07_10995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLG07_11000	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NLG07_11015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLG07_11020	COG1286	toxin biosynthetic process
NLG07_11030	COG0285	dihydrofolate synthase activity
NLG07_11035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLG07_11055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NLG07_11080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NLG07_11080	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NLG07_11095	COG3101	peptidyl-lysine hydroxylation
NLG07_11110	COG1902	pentaerythritol trinitrate reductase activity
NLG07_11110	COG0446	pyridine nucleotide-disulphide oxidoreductase
NLG07_11120	COG2186	Transcriptional regulator
NLG07_11125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NLG07_11130	COG2983	Belongs to the UPF0260 family
NLG07_11140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NLG07_11145	COG0697	spore germination
NLG07_11175	COG1214	PFAM Peptidase M22, glycoprotease
NLG07_11180	COG1199	ATP-dependent helicase activity
NLG07_11205	COG3268	Saccharopine dehydrogenase
NLG07_11220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NLG07_11225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NLG07_11230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLG07_11235	COG0131	Imidazoleglycerol-phosphate dehydratase
NLG07_11235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NLG07_11240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NLG07_11250	COG2264	protein methyltransferase activity
NLG07_11260	COG1320	monovalent cation:proton antiporter activity
NLG07_11265	COG2212	antiporter activity
NLG07_11270	COG1863	multisubunit Na H antiporter MnhE subunit
NLG07_11275	COG0651	ATP synthesis coupled electron transport
NLG07_11280	COG1006	Multisubunit Na H antiporter MnhC subunit
NLG07_11285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NLG07_11285	COG2111	Na H antiporter
NLG07_11305	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NLG07_11310	COG2885	chlorophyll binding
NLG07_11315	COG0823	Involved in the tonB-independent uptake of proteins
NLG07_11330	COG0811	peptide transport
NLG07_11335	COG0824	Thioesterase
NLG07_11340	COG2255	four-way junction helicase activity
NLG07_11345	COG0632	four-way junction helicase activity
NLG07_11350	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NLG07_11355	COG0494	nUDIX hydrolase
NLG07_11360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NLG07_11365	COG3842	ATPase activity
NLG07_11370	COG1178	ABC-type Fe3 transport system permease component
NLG07_11375	COG1840	ABC-type Fe3 transport system, periplasmic component
NLG07_11385	COG0077	Prephenate dehydratase
NLG07_11385	COG1605	Chorismate mutase
NLG07_11390	COG0287	Prephenate dehydrogenase
NLG07_11390	COG1605	Chorismate mutase
NLG07_11395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NLG07_11410	COG0047	phosphoribosylformylglycinamidine synthase activity
NLG07_11410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLG07_11425	COG0590	tRNA wobble adenosine to inosine editing
NLG07_11440	COG0825	malonyl-CoA metabolic process
NLG07_11445	COG0587	DNA-directed DNA polymerase activity
NLG07_11460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NLG07_11465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NLG07_11480	COG0750	zinc metalloprotease
NLG07_11485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NLG07_11490	COG0575	Belongs to the CDS family
NLG07_11505	COG0528	UMP kinase activity
NLG07_11515	COG0052	Belongs to the universal ribosomal protein uS2 family
NLG07_11525	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NLG07_11530	COG2171	N-acyltransferase activity
NLG07_11540	COG0564	pseudouridine synthase activity
NLG07_11575	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NLG07_11575	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NLG07_11580	COG1611	Belongs to the LOG family
NLG07_11585	COG0473	3-isopropylmalate dehydrogenase activity
NLG07_11590	COG3568	Endonuclease Exonuclease Phosphatase
NLG07_11590	COG1555	photosystem II stabilization
NLG07_11595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NLG07_11615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NLG07_11620	COG2853	Lipoprotein
NLG07_11635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NLG07_11640	COG1138	Cytochrome C-type biogenesis protein
NLG07_11650	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NLG07_11655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NLG07_11660	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NLG07_11680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLG07_11695	COG3012	SEC-C Motif Domain Protein
NLG07_11705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLG07_11710	COG0473	3-isopropylmalate dehydrogenase activity
NLG07_11720	COG0066	3-isopropylmalate dehydratase activity
NLG07_11730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NLG07_11740	COG0513	Belongs to the DEAD box helicase family
NLG07_11750	COG3267	Type II secretory pathway component ExeA
NLG07_11750	COG3409	Peptidoglycan-binding domain 1 protein
NLG07_11760	COG1346	cytolysis
NLG07_11820	COG4372	Transposase
NLG07_11825	COG3436	PFAM IS66 Orf2 family protein