locus-tag	class	description
CW735_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CW735_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CW735_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CW735_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CW735_00030	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CW735_00035	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
CW735_00040	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CW735_00050	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
CW735_00060	ENOG4106RE7	Cytochrome
CW735_00065	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CW735_00070	ENOG4105C2M	dna polymerase I
CW735_00080	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
CW735_00085	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CW735_00090	ENOG4105C1A	potassium transporter peripheral membrane
CW735_00095	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CW735_00105	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CW735_00110	ENOG4108WZM	domain protein
CW735_00115	ENOG4105C79	DNA protecting protein DprA
CW735_00120	ENOG4108RPN	Protein smg homolog
CW735_00125	ENOG4108WI1	Dna topoisomerase
CW735_00130	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CW735_00135	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CW735_00140	ENOG4105EIF	outer membrane protein W
CW735_00150	ENOG4105E2X	shikimate dehydrogenase
CW735_00155	ENOG4108Z0R	Transferase
CW735_00185	ENOG4105C0B	DNA polymerase III (alpha subunit)
CW735_00215	ENOG4105IIU	Aminopeptidase
CW735_00230	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CW735_00240	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CW735_00245	ENOG4105W5Q	DNA repair protein (RadC
CW735_00265	ENOG4105E3R	(LipO)protein
CW735_00280	ENOG4105KDC	50s ribosomal protein l28
CW735_00285	ENOG4105W0E	50S ribosomal protein L33
CW735_00295	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CW735_00300	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CW735_00305	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CW735_00310	ENOG4105DKP	glycosyl transferase, family 9
CW735_00325	ENOG4105BZU	Histidine kinase
CW735_00330	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CW735_00335	ENOG4105CPQ	Dehydrogenase
CW735_00340	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CW735_00355	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CW735_00360	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CW735_00365	ENOG4105W0Z	cytoplasmic protein
CW735_00370	ENOG4105C4R	Atp-dependent dna helicase
CW735_00375	ENOG4105BZU	Histidine kinase
CW735_00380	ENOG4105MPD	Cytochrome
CW735_00390	ENOG4107QI6	Cysteine desulfurase
CW735_00400	ENOG4106IJN	integrase catalytic domain-containing protein
CW735_00405	ENOG4105F5W	AtP-binding protein
CW735_00420	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CW735_00425	ENOG4105BZS	acriflavin resistance protein
CW735_00430	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CW735_00450	ENOG4108QDA	dioxygenase
CW735_00460	ENOG4105BZU	Histidine kinase
CW735_00480	ENOG4105C29	acyl-CoA thioesterase
CW735_00525	ENOG4105CAF	HipA N-terminal domain protein
CW735_00530	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
CW735_00555	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CW735_00575	ENOG4105CNM	Receptor
CW735_00590	ENOG4105BZU	Histidine kinase
CW735_00595	ENOG4105WH1	Two component transcriptional regulator luxr family
CW735_00615	ENOG4105HMI	Membrane
CW735_00640	ENOG4107RUZ	Sss sodium solute transporter superfamily
CW735_00670	ENOG4107RNH	Outer membrane receptor FepA
CW735_00675	ENOG4105C1G	acyl-Coa dehydrogenase
CW735_00680	ENOG4105DQS	Transcriptional regulator
CW735_00690	ENOG4105CM6	amino acid regulated cytosolic protein
CW735_00695	ENOG4106K28	UPF0283 membrane protein
CW735_00705	ENOG410601J	HemY protein
CW735_00710	ENOG4105ECF	c-methyltransferase
CW735_00715	ENOG41076E6	Uroporphyrinogen-III Synthase
CW735_00720	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CW735_00725	ENOG4105BZU	Histidine kinase
CW735_00730	ENOG4106CJB	Phospholipase Carboxylesterase
CW735_00735	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CW735_00740	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CW735_00745	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CW735_00750	ENOG4105KME	endoribonuclease L-psp
CW735_00755	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
CW735_00760	ENOG4105CB5	ATP-dependent DNA helicase recG
CW735_00765	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
CW735_00785	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
CW735_00790	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CW735_00795	ENOG4105CBX	hi0933 family
CW735_00815	ENOG4105DFU	Cell wall formation (By similarity)
CW735_00860	ENOG4105BZU	Histidine kinase
CW735_00895	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CW735_00900	ENOG4105BZS	acriflavin resistance protein
CW735_00920	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_00925	ENOG4105CYC	Transferase
CW735_00945	ENOG4108N3W	hemolysin secretion protein
CW735_00955	ENOG4108NST	exported protein
CW735_00960	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CW735_00965	ENOG4105BZU	Histidine kinase
CW735_00980	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CW735_00985	ENOG4105CJW	magnesium transporter
CW735_00990	ENOG4105FR1	rard protein
CW735_00995	ENOG4105BZU	Histidine kinase
CW735_01000	ENOG4105C4R	Atp-dependent dna helicase
CW735_01005	ENOG4105D7W	serine acetyltransferase
CW735_01010	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
CW735_01015	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CW735_01025	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CW735_01030	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CW735_01045	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_01050	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
CW735_01055	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CW735_01065	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CW735_01070	ENOG4105DFU	Cell wall formation (By similarity)
CW735_01075	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CW735_01080	ENOG4105F0N	pyrophosphate phospho-hydrolase
CW735_01115	ENOG4107KET	secretion protein, HlyD family
CW735_01120	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CW735_01145	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CW735_01150	ENOG4107RDB	Major Facilitator
CW735_01165	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CW735_01170	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CW735_01175	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CW735_01180	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_01205	ENOG4105EKQ	RNA-directed DNA polymerase
CW735_01210	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_01225	ENOG4107RUZ	Sss sodium solute transporter superfamily
CW735_01245	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CW735_01250	ENOG4105E98	transcriptional regulator DeoR family
CW735_01255	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CW735_01265	ENOG4105DFF	Rod shape-determining protein mreb
CW735_01270	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CW735_01275	ENOG4105VQ7	Rod shape-determining protein MreD
CW735_01280	ENOG4108Z03	MAF-like protein
CW735_01285	ENOG4105C03	ribonuclease
CW735_01290	ENOG4105QD6	exported protein
CW735_01300	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CW735_01305	ENOG4105N42	UPF0307 protein
CW735_01310	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CW735_01335	ENOG4105ECQ	AraC Family Transcriptional Regulator
CW735_01340	ENOG4105CNT	hydrolase family 2
CW735_01345	ENOG41065U4	response regulator
CW735_01350	ENOG4105BZU	Histidine kinase
CW735_01355	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CW735_01360	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CW735_01365	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CW735_01370	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CW735_01375	ENOG4105CEN	a g-specific adenine glycosylase
CW735_01380	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CW735_01430	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
CW735_01435	ENOG4105CVR	type I restriction-modification system
CW735_01500	ENOG4105CFG	Acts as a chaperone (By similarity)
CW735_01520	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_01525	ENOG4105BZU	Histidine kinase
CW735_01540	ENOG4105BZU	Histidine kinase
CW735_01550	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CW735_01565	ENOG4105C0A	alcohol dehydrogenase
CW735_01590	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CW735_01600	ENOG4107QM5	aconitate hydratase
CW735_01605	ENOG4107QHF	type ii secretion system protein e
CW735_01610	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CW735_01615	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CW735_01620	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CW735_01625	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CW735_01630	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CW735_01635	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CW735_01640	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CW735_01645	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CW735_01650	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CW735_01655	ENOG41083MP	50s ribosomal protein l29
CW735_01660	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CW735_01665	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CW735_01680	ENOG41069D7	Methyl-accepting chemotaxis
CW735_01690	ENOG4105DGW	oligopeptidase A
CW735_01710	ENOG4105CQ7	ATP-dependent helicase
CW735_01725	ENOG4105CVE	Lytic murein transglycosylase
CW735_01730	ENOG4105BZ4	penicillin-binding protein
CW735_01740	ENOG4105CKW	Inner membrane protein yedI
CW735_01750	ENOG4108YZA	Nitrogen regulatory protein pii
CW735_01760	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CW735_01765	ENOG4105EZR	dyp-type peroxidase family protein
CW735_01775	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CW735_01780	ENOG4105CXT	aspartate transcarbamylase
CW735_01785	ENOG4108IG5	Transcriptional regulator
CW735_01790	ENOG410624X	efflux transporter, rnd family, mfp subunit
CW735_01805	ENOG4105BZU	Histidine kinase
CW735_01810	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CW735_01820	ENOG4105BZU	Histidine kinase
CW735_01830	ENOG4105C26	Dehydrogenase
CW735_01835	ENOG4105F4X	arginine
CW735_01840	ENOG4105C8Y	Acetylornithine aminotransferase
CW735_01850	ENOG4105DDQ	anthranilate synthase
CW735_01855	ENOG4105C31	Tryptophanyl-tRNA synthetase
CW735_01860	ENOG4105DJV	ribulose-phosphate 3-epimerase
CW735_01890	ENOG4105D49	3-dehydroquinate synthase
CW735_01895	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CW735_01900	ENOG4105E4G	Type IV pilus
CW735_01925	ENOG4108JQC	penicillin-binding protein 1A
CW735_01930	ENOG4107R1I	NAD-dependent malic enzyme
CW735_01960	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CW735_01970	ENOG4105D7T	ABC transporter
CW735_01985	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CW735_02000	ENOG4107QZF	nitrite reductase NADPH large subunit
CW735_02010	ENOG4105TMB	Formate nitrite transporter
CW735_02020	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CW735_02035	ENOG4105CYM	Glutathione S-transferase
CW735_02050	ENOG4107QZM	n-acetylglutamate synthase
CW735_02055	ENOG4105CH7	arginosuccinase
CW735_02060	ENOG4105CDH	Citrulline--aspartate ligase
CW735_02065	ENOG4105DBV	ornithine carbamoyltransferase
CW735_02070	ENOG4105CAS	nag kinase
CW735_02075	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CW735_02080	ENOG4108Z5K	methylglyoxal synthase
CW735_02095	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CW735_02110	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CW735_02115	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CW735_02120	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CW735_02130	ENOG4107YZP	Rhodanese domain protein
CW735_02135	ENOG41063SB	peptidase
CW735_02140	ENOG4105PXI	polysaccharide deacetylase
CW735_02150	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
CW735_02160	ENOG4105DJ4	phosphatidylserine decarboxylase
CW735_02165	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CW735_02170	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CW735_02205	ENOG4105C7K	acetolactate synthase
CW735_02210	ENOG4108ZP8	Acetolactate synthase small subunit
CW735_02220	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CW735_02225	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CW735_02230	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CW735_02240	ENOG4105F8V	Hydrolase, tatD family
CW735_02245	ENOG4105BZU	Histidine kinase
CW735_02250	ENOG4105D52	delta-aminolevulinic acid dehydratase
CW735_02255	ENOG4105C9X	ppx gppa phosphatase
CW735_02260	ENOG4105C1J	atp-dependent rna helicase
CW735_02265	ENOG4105K63	Thioredoxin
CW735_02275	ENOG4105CH2	amidohydrolase
CW735_02280	ENOG4105BZU	Histidine kinase
CW735_02285	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CW735_02290	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CW735_02300	ENOG41080T7	secreted protein
CW735_02315	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CW735_02325	ENOG4107QR8	Thioredoxin
CW735_02345	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CW735_02350	ENOG4105C26	Dehydrogenase
CW735_02365	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CW735_02370	ENOG4107S6Z	Na H antiporter
CW735_02380	ENOG4105EHZ	conserved protein UCP016719
CW735_02385	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CW735_02390	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CW735_02420	ENOG4105K3M	)-transporter
CW735_02490	ENOG4105E5H	Transposase
CW735_02560	ENOG4105EKQ	RNA-directed DNA polymerase
CW735_02585	ENOG4105CHU	acetyl-coa acetyltransferase
CW735_02590	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CW735_02595	ENOG4107SC1	transglycosylase
CW735_02600	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
CW735_02610	ENOG4105EAH	synthase
CW735_02615	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CW735_02620	ENOG4105K46	50S ribosomal protein l27
CW735_02625	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CW735_02640	ENOG4108K5P	(LipO)protein
CW735_02645	ENOG4108UM1	dedA family
CW735_02650	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CW735_02655	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CW735_02665	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CW735_02670	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CW735_02680	ENOG4105C8Q	Methyl-accepting chemotaxis
CW735_02685	ENOG4105C26	Dehydrogenase
CW735_02695	ENOG4105I7R	Adenylate cyclase
CW735_02705	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
CW735_02710	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CW735_02715	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
CW735_02720	ENOG4105HF0	Membrane
CW735_02725	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CW735_02735	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CW735_02760	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
CW735_02815	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CW735_02820	ENOG4105BZU	Histidine kinase
CW735_02825	ENOG4105EYM	Major Facilitator superfamily
CW735_02840	ENOG4105D3G	Pseudouridine synthase
CW735_02845	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CW735_02855	ENOG4108IAB	Phoh family
CW735_02865	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CW735_02870	ENOG4105C1J	atp-dependent rna helicase
CW735_02885	ENOG4105DFG	type I secretion outer membrane protein
CW735_02890	ENOG41087AY	ADP-Ribose pyrophosphatase
CW735_02895	ENOG4108SX3	cytoplasmic protein
CW735_02900	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CW735_02905	ENOG4105IPS	esterase
CW735_02910	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CW735_02935	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CW735_02940	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CW735_02945	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CW735_02950	ENOG4105UGU	tonB-dependent Receptor
CW735_02985	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CW735_02990	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CW735_03000	ENOG4105M85	Bola protein
CW735_03005	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CW735_03020	ENOG4105CHH	sulfate transporter
CW735_03035	ENOG4107QYG	anthranilate phosphoribosyltransferase
CW735_03045	ENOG4108Z33	Thiol disulfide Interchange Protein
CW735_03055	ENOG4105E27	serine threonine protein kinase
CW735_03060	ENOG4105C58	cytochrome c oxidase accessory protein ccog
CW735_03075	ENOG4105CSU	acyl-Coa dehydrogenase
CW735_03080	ENOG4105CHR	reductase
CW735_03090	ENOG4105CXK	mandelate racemase muconate lactonizing
CW735_03095	ENOG4105MP9	class II Aldolase
CW735_03110	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CW735_03115	ENOG4105BZS	acriflavin resistance protein
CW735_03135	ENOG4105C8Q	Methyl-accepting chemotaxis
CW735_03140	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_03145	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CW735_03150	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CW735_03160	ENOG4105VCC	30S ribosomal protein S21
CW735_03165	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CW735_03175	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CW735_03190	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CW735_03195	ENOG4105K59	histidine triad (HIT) protein
CW735_03210	ENOG4105DKK	Benzoate
CW735_03215	ENOG4108JCI	Transcriptional regulator
CW735_03220	ENOG4105DH7	May be involved in recombination (By similarity)
CW735_03230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CW735_03235	ENOG4105BZU	Histidine kinase
CW735_03275	ENOG4109015	Biopolymer transport protein exbD tolR
CW735_03280	ENOG41067XB	TonB family
CW735_03290	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CW735_03295	ENOG4105BZU	Histidine kinase
CW735_03305	ENOG4105CEY	Amp-dependent synthetase and ligase
CW735_03315	ENOG4105D8V	Glucose sorbosone dehydrogenase
CW735_03320	ENOG4107QIJ	Aconitate hydratase 2
CW735_03335	ENOG4105BZU	Histidine kinase
CW735_03385	ENOG410600T	transposase
CW735_03410	ENOG4105GR3	Histidine kinase
CW735_03440	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CW735_03450	ENOG4105N7H	Cytochrome
CW735_03510	ENOG4108IJF	Heavy metal efflux pump, CzcA
CW735_03520	ENOG4107ZSV	Receptor
CW735_03550	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CW735_03555	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CW735_03565	ENOG4105CFH	Aspartokinase
CW735_03575	ENOG4108NVR	Methyl-accepting chemotaxis
CW735_03585	ENOG4105NWN	ApaG protein
CW735_03590	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CW735_03595	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CW735_03600	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CW735_03605	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CW735_03610	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CW735_03615	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CW735_03620	ENOG4105T95	Thiol disulfide interChange protein
CW735_03625	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CW735_03635	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CW735_03640	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CW735_03645	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CW735_03650	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CW735_03655	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CW735_03660	ENOG4105DXN	mazG family
CW735_03680	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CW735_03685	ENOG4108UJD	30S ribosomal protein S9
CW735_03690	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CW735_03695	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CW735_03700	ENOG4105EIX	cytochrome c1
CW735_03705	ENOG4107MKT	Stringent starvation protein a
CW735_03710	ENOG4105KB2	stringent starvation protein b
CW735_03715	ENOG410642W	LysR family Transcriptional regulator
CW735_03750	ENOG4105CJW	magnesium transporter
CW735_03755	ENOG41080Z8	PHOSPHOCARRIER protein
CW735_03760	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CW735_03765	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CW735_03770	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CW735_03775	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CW735_03780	ENOG4108IUZ	ABC transporter
CW735_03785	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CW735_03795	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CW735_03800	ENOG4105C2X	Arabinose 5-phosphate isomerase
CW735_03810	ENOG4105DHJ	ABC, transporter
CW735_03815	ENOG4105CY3	ABC transporter, permease
CW735_03820	ENOG4107PE3	Mammalian cell entry related domain protein
CW735_03825	ENOG4105E3I	toluene tolerance
CW735_03835	ENOG4105VFK	BolA family
CW735_03840	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CW735_03845	ENOG4105C0H	protease
CW735_03850	ENOG4105C0H	protease
CW735_03860	ENOG4105D6Z	AFG1 family ATPase
CW735_03865	ENOG4105CDY	transcriptional regulatory protein
CW735_03870	ENOG4105BZU	Histidine kinase
CW735_03875	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CW735_03890	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CW735_03910	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CW735_03915	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CW735_03920	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CW735_03925	ENOG4105BZA	Phosphoglycerate kinase
CW735_03930	ENOG4105WYW	fructose-bisphosphate aldolase
CW735_03990	ENOG4105C9X	ppx gppa phosphatase
CW735_04005	ENOG4105C8U	phosphate abc transporter
CW735_04015	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CW735_04025	ENOG4105CJ3	phosphate transporter
CW735_04030	ENOG4105Q9Y	Universal stress protein
CW735_04035	ENOG4105C5Q	Transcriptional regulator
CW735_04045	ENOG4108UT2	hemolysin iii
CW735_04060	ENOG4105K56	Transcriptional regulator
CW735_04065	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CW735_04090	ENOG4108ZIG	UPF0231 protein
CW735_04095	ENOG4108VKG	metal-dependent hydrolase
CW735_04100	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CW735_04120	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CW735_04125	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CW735_04140	ENOG4105ETE	Transcriptional regulator (LacI family
CW735_04150	ENOG4107RH8	nuclease SbcCD subunit D
CW735_04155	ENOG4105EYH	Exonuclease
CW735_04160	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
CW735_04165	ENOG4105BZU	Histidine kinase
CW735_04175	ENOG4105RW8	MltA-interacting MipA family protein
CW735_04180	ENOG4105RD7	BadF BadG BcrA BcrD
CW735_04185	ENOG4105C5H	ABC transporter
CW735_04190	ENOG4105EVH	UPF0753 protein
CW735_04195	ENOG4108TWJ	NADH dehydrogenase subunit 5
CW735_04200	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CW735_04205	ENOG4105DND	Transcriptional regulator
CW735_04220	ENOG4105D64	Mechanosensitive ion channel
CW735_04350	ENOG41067MG	lrgb family
CW735_04380	ENOG4105CSA	Coproporphyrinogen iii oxidase
CW735_04385	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CW735_04390	ENOG4105C1J	atp-dependent rna helicase
CW735_04395	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CW735_04400	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CW735_04415	ENOG4105CPI	Metal Dependent Phosphohydrolase
CW735_04420	ENOG4105DFD	Na H antiporter
CW735_04425	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CW735_04430	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CW735_04435	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CW735_04440	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CW735_04450	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CW735_04455	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CW735_04460	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CW735_04470	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CW735_04485	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_04490	ENOG4108IUW	ABC transporter
CW735_04495	ENOG4108SDH	ABC, transporter
CW735_04520	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CW735_04525	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CW735_04530	ENOG41060IM	Heme exporter protein
CW735_04535	ENOG4105X3C	heme exporter protein
CW735_04540	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CW735_04545	ENOG4105DA4	cytochrome c-type biogenesis protein
CW735_04550	ENOG4107QX9	Thiol disulfide interChange protein
CW735_04555	ENOG4108M1T	Cytochrome c-type biogenesis protein
CW735_04565	ENOG410903C	(LipO)protein
CW735_04570	ENOG4105CMR	udp-glucose 4-epimerase
CW735_04580	ENOG4105DUX	Transporter
CW735_04590	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CW735_04595	ENOG4105KQC	Competence protein
CW735_04600	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CW735_04620	ENOG4105EWT	decarboxylase family
CW735_04625	ENOG4105BZU	Histidine kinase
CW735_04630	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CW735_04635	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
CW735_04685	ENOG4105DR9	pseudouridine synthase
CW735_04690	ENOG4105QDK	Flavodoxin
CW735_04705	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CW735_04710	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CW735_04715	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CW735_04725	ENOG4105CE9	30S ribosomal protein S2
CW735_04730	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CW735_04735	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CW735_04740	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CW735_04745	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CW735_04750	ENOG4105KNE	Phosphatidate cytidylyltransferase
CW735_04755	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CW735_04770	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
CW735_04775	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CW735_04780	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CW735_04785	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CW735_04790	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CW735_04795	ENOG4105C0B	DNA polymerase III (alpha subunit)
CW735_04800	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CW735_04805	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CW735_04810	ENOG4105BZU	Histidine kinase
CW735_04825	ENOG4108Z6B	deaminase
CW735_04830	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CW735_04835	ENOG4108ETH	Formylglycinamide ribotide synthetase
CW735_04840	ENOG4108DG9	Smr protein MutS2
CW735_04875	ENOG4107R88	Chemotaxis protein (CheV)
CW735_04880	ENOG4105BZU	Histidine kinase
CW735_04885	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CW735_04890	ENOG4108ZC9	flagellar basal-body rod protein flgc
CW735_04895	ENOG4105W00	Flagellar hook capping protein
CW735_04900	ENOG4105BZE	flagellar hook protein, FlgE
CW735_04905	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CW735_04910	ENOG4105CGA	flagellar basal-body rod protein FlgG
CW735_04915	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CW735_04920	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CW735_04925	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CW735_04930	ENOG4105E1Q	flagellar hook-associated protein
CW735_04945	ENOG4105I03	Flagellin
CW735_04955	ENOG4105I03	Flagellin
CW735_04960	ENOG4105I03	Flagellin
CW735_04965	ENOG41063QE	flagellar protein FlaG
CW735_04970	ENOG4107W9T	flagellar hook-associated
CW735_04975	ENOG4105MQ3	flagellar protein FliS
CW735_05005	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CW735_05030	ENOG4105CHR	reductase
CW735_05035	ENOG4108IUS	Transketolase
CW735_05040	ENOG4108HHA	Transketolase
CW735_05065	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CW735_05070	ENOG4105C5E	polysaccharide biosynthesis protein
CW735_05085	ENOG4105BZU	Histidine kinase
CW735_05090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CW735_05095	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CW735_05100	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CW735_05105	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CW735_05115	ENOG4108JIR	Flagellum-specific ATP synthase
CW735_05135	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CW735_05140	ENOG4105DD5	Flagellar motor switch protein
CW735_05145	ENOG4105VTB	flagellar biosynthesis protein fliO
CW735_05150	ENOG4105CN7	Flagellar biosynthetic protein FliP
CW735_05155	ENOG4105VS8	Flagellar biosynthetic protein fliq
CW735_05160	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CW735_05165	ENOG4105D00	flagellar biosynthetic protein flhB
CW735_05170	ENOG4105D7B	Flagellar biosynthesis protein flha
CW735_05175	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CW735_05185	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CW735_05190	ENOG4108VYJ	response regulator receiver protein
CW735_05195	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CW735_05200	ENOG4105CBS	Chea signal transduction histidine kinase
CW735_05210	ENOG4107QJE	Chromosome Partitioning Protein
CW735_05220	ENOG4105YFD	chemotaxis, protein
CW735_05230	ENOG4105CVG	Homoserine O-transsuccinylase
CW735_05235	ENOG4105C3R	Methionine synthase
CW735_05240	ENOG4105C3R	Methionine synthase
CW735_05250	ENOG4105NBK	UPF0345 protein
CW735_05255	ENOG4105DZ2	Transcriptional regulator
CW735_05260	ENOG4105C5Q	Transcriptional regulator
CW735_05265	ENOG4107B2H	carbonic anhydrase
CW735_05270	ENOG4105CHH	sulfate transporter
CW735_05275	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CW735_05280	ENOG4105C9K	Endothelin-converting enzyme 1
CW735_05295	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CW735_05300	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CW735_05325	ENOG4107QSA	Oxaloacetate decarboxylase
CW735_05330	ENOG4105D9Q	decarboxylase (Beta subunit)
CW735_05335	ENOG4108JQ2	peptide transport system atp-binding protein
CW735_05340	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
CW735_05345	ENOG4108EU3	peptide transport system, permease
CW735_05350	ENOG4108I5W	peptide transport system, permease protein
CW735_05355	ENOG4105DEF	Extracellular solute-binding protein, family 5
CW735_05360	ENOG4105E51	psp operon transcriptional activator
CW735_05365	ENOG41087YS	Phage shock protein A
CW735_05370	ENOG4105YYT	phage shock protein B
CW735_05380	ENOG4105MIR	Phenylalanine 4-monooxygenase
CW735_05395	ENOG4108RXX	maleylacetoacetate isomerase
CW735_05400	ENOG4108XM1	transcriptional regulator AsnC family
CW735_05420	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
CW735_05435	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_05460	ENOG4109015	Biopolymer transport protein exbD tolR
CW735_05465	ENOG410822N	TonB family
CW735_05475	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
CW735_05515	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CW735_05530	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CW735_05535	ENOG4105C75	arginyL-tRNA synthetase
CW735_05560	ENOG4105C6T	cysteine synthase
CW735_05570	ENOG4105BZU	Histidine kinase
CW735_05600	ENOG4105CRK	lysyL-tRNA synthetase
CW735_05605	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CW735_05610	ENOG4108W1A	pseudouridine synthase
CW735_05625	ENOG4105D9M	gamma-glutamylcysteine synthetase
CW735_05635	ENOG4108DG9	Smr protein MutS2
CW735_05640	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CW735_05645	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CW735_05655	ENOG4105ED1	spovr family
CW735_05660	ENOG4106AKX	UPF0229 protein
CW735_05665	ENOG4105CYN	Serine protein kinase
CW735_05675	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CW735_05680	ENOG4105M2J	Glutaredoxin
CW735_05685	ENOG4105D05	Receptor
CW735_05710	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CW735_05715	ENOG4105EIY	sodium-type flagellar protein motY
CW735_05720	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CW735_05725	ENOG4108UYE	Lactoylglutathione lyase
CW735_05730	ENOG4105VEQ	Cold shock protein
CW735_05745	ENOG4105CSM	endonuclease III
CW735_05750	ENOG4105DZB	Electron transport complex
CW735_05755	ENOG4108UQQ	Electron transport complex
CW735_05760	ENOG4105D6A	Electron transport complex
CW735_05770	ENOG4108R3D	Electron transport complex
CW735_05775	ENOG4105DGN	Electron transport complex
CW735_05790	ENOG4107QI1	Mate efflux family protein
CW735_05795	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CW735_05815	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CW735_05820	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CW735_05830	ENOG4105CAQ	asparagine synthetase
CW735_05855	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CW735_05860	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CW735_05865	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
CW735_05870	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CW735_05875	ENOG4105CK7	Sodium proline symporter
CW735_05880	ENOG4105BZU	Histidine kinase
CW735_05915	ENOG4107QVM	von Willebrand factor, type A
CW735_05935	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CW735_05940	ENOG4105CHU	acetyl-coa acetyltransferase
CW735_05945	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CW735_05965	ENOG4105BZU	Histidine kinase
CW735_05975	ENOG4108BY2	phosphohistidine phosphatase
CW735_05985	ENOG4108JU6	CBS domain protein
CW735_05990	ENOG4106KVJ	cytochrome C assembly protein
CW735_05995	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CW735_06025	ENOG4105BZS	acriflavin resistance protein
CW735_06035	ENOG4105BZ1	(ABC) transporter
CW735_06040	ENOG4105D64	Mechanosensitive ion channel
CW735_06050	ENOG4105K5M	30s ribosomal protein S16
CW735_06055	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CW735_06060	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CW735_06065	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CW735_06080	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CW735_06095	ENOG4108VYJ	response regulator receiver protein
CW735_06100	ENOG4108ZJT	translation initiation factor, Sui1
CW735_06110	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CW735_06120	ENOG4105BZU	Histidine kinase
CW735_06130	ENOG4107WP9	Histidine kinase
CW735_06140	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CW735_06150	ENOG4105C9M	aspartyl-trna synthetase
CW735_06155	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CW735_06160	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CW735_06165	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CW735_06170	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CW735_06175	ENOG4107YD3	Thioesterase
CW735_06180	ENOG4105E02	MotA TolQ exbB proton channel
CW735_06185	ENOG4105M8F	Biopolymer transport protein exbD tolR
CW735_06195	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CW735_06200	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CW735_06205	ENOG4105UFD	tol-pal system protein YbgF
CW735_06225	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CW735_06250	ENOG4105BZU	Histidine kinase
CW735_06280	ENOG4105BZS	acriflavin resistance protein
CW735_06290	ENOG4108XG4	DNA-binding transcriptional regulator
CW735_06305	ENOG4105Y49	secretion protein, HlyD family
CW735_06310	ENOG4105BZU	Histidine kinase
CW735_06320	ENOG4105DY2	Paraquat-inducible protein b
CW735_06325	ENOG4105F1S	paraquat-inducible protein a
CW735_06335	ENOG4105CRW	Short chain fatty acid transporter
CW735_06340	ENOG4105C5S	asparaginyl-tRNA synthetase
CW735_06370	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CW735_06375	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CW735_06380	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CW735_06385	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CW735_06390	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
CW735_06395	ENOG4105KJF	protein tyrosine phosphatase
CW735_06400	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
CW735_06405	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
CW735_06410	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CW735_06425	ENOG4108JJ7	ABC transporter
CW735_06450	ENOG4105BZU	Histidine kinase
CW735_06455	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CW735_06480	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CW735_06530	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CW735_06535	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CW735_06555	ENOG4108UJV	acyl-CoA thioesterase i
CW735_06560	ENOG4108I0Y	(ABC) transporter
CW735_06565	ENOG4105CV6	ABC transporter, permease
CW735_06570	ENOG4105ECP	epimerase
CW735_06575	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
CW735_06580	ENOG4105DSF	transport protein
CW735_06585	ENOG4105IFJ	Histidine kinase
CW735_06590	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CW735_06605	ENOG4105K9H	YciI-like protein
CW735_06610	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CW735_06615	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CW735_06620	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CW735_06625	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CW735_06635	ENOG4105CRQ	synthase (Component I)
CW735_06640	ENOG4105DB7	PHP domain protein
CW735_06645	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CW735_06655	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CW735_06660	ENOG4105FE9	pseudouridine synthase
CW735_06665	ENOG4105CV8	reductase
CW735_06670	ENOG4107SDU	Methyl-accepting chemotaxis
CW735_06680	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CW735_06695	ENOG4108UW5	maltose o-acetyltransferase
CW735_06705	ENOG4106BRA	Membrane
CW735_06710	ENOG4105D6Z	AFG1 family ATPase
CW735_06725	ENOG4107RBR	Receptor
CW735_06735	ENOG4105FQ6	thiopurine methyltransferase
CW735_06740	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CW735_06745	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CW735_06755	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
CW735_06760	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CW735_06775	ENOG4105DWV	Homoserine O-trans-acetylase
CW735_06780	ENOG4105CY2	Citrate transporter
CW735_06795	ENOG4105IU3	Glutathione S-transferase
CW735_06825	ENOG4105D7V	transposase
CW735_06830	ENOG4105BZU	Histidine kinase
CW735_06835	ENOG4105BZU	Histidine kinase
CW735_06840	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CW735_06845	ENOG4105CFG	Acts as a chaperone (By similarity)
CW735_06850	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CW735_06860	ENOG4105T86	cytochrome C
CW735_06865	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CW735_06875	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CW735_06880	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CW735_06885	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CW735_06890	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CW735_06900	ENOG4108ZNX	Heat shock protein
CW735_06905	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CW735_06910	ENOG4108DNC	Involved in acetate metabolism (By similarity)
CW735_06925	ENOG4105DYB	Isoaspartyl dipeptidase
CW735_06940	ENOG4105W08	virulence gene repressor rsal
CW735_06945	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
CW735_06955	ENOG4105D9M	gamma-glutamylcysteine synthetase
CW735_06970	ENOG4108JU5	Magnesium and cobalt efflux protein
CW735_06975	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CW735_06980	ENOG4105C9A	Phoh family
CW735_06985	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CW735_06990	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CW735_07005	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CW735_07010	ENOG4105C26	Dehydrogenase
CW735_07030	ENOG4107RNH	Outer membrane receptor FepA
CW735_07035	ENOG4108S4H	thioesterase Superfamily protein
CW735_07040	ENOG4107XWI	flavin reductase domain protein, FMN-binding
CW735_07055	ENOG4105CEY	Amp-dependent synthetase and ligase
CW735_07060	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CW735_07065	ENOG4105VNG	YcgL domain-containing protein
CW735_07075	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CW735_07080	ENOG4108ZZ3	UPF0260 protein
CW735_07085	ENOG4108428	Inherit from COG: -acetyltransferase
CW735_07090	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CW735_07095	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CW735_07100	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CW735_07125	ENOG4108UH6	UPF0754 membrane protein
CW735_07135	ENOG4105D8T	Acyltransferase
CW735_07155	ENOG4108VUG	Enoyl-CoA hydratase
CW735_07160	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CW735_07165	ENOG4105D41	biosynthesis protein thiH
CW735_07170	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CW735_07180	ENOG4105D06	uba thif-type nad fad binding protein
CW735_07185	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CW735_07190	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CW735_07195	ENOG4105DAA	L-lactate
CW735_07215	ENOG4108BPE	-transporting atpase
CW735_07310	ENOG4105EKQ	RNA-directed DNA polymerase
CW735_07340	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CW735_07345	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CW735_07355	ENOG4105MP9	class II Aldolase
CW735_07360	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CW735_07380	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CW735_07385	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CW735_07390	ENOG4108S3P	Sporulation domain protein
CW735_07395	ENOG4105E96	Colicin v production protein
CW735_07400	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CW735_07410	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
CW735_07425	ENOG4105CIS	alcohol dehydrogenase
CW735_07430	ENOG4105BZU	Histidine kinase
CW735_07440	ENOG4105KVH	Transcriptional regulator
CW735_07475	ENOG4105G6Z	alkaline phosphatase
CW735_07480	ENOG4105G6Z	alkaline phosphatase
CW735_07490	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CW735_07495	ENOG4105C8N	cysteinyl-tRNA synthetase
CW735_07500	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CW735_07510	ENOG4105E9H	Lytic Murein transglycosylase
CW735_07515	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CW735_07520	ENOG4105D1A	Methyltransferase
CW735_07525	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CW735_07530	ENOG4105D1F	ATP-binding protein
CW735_07540	ENOG4105DHP	deoxycytidine triphosphate deaminase
CW735_07545	ENOG4105C8P	)-transporter
CW735_07565	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
CW735_07570	ENOG4107R3N	Filamentation induced by cAMP protein fic
CW735_07575	ENOG4105CVR	type I restriction-modification system
CW735_07595	ENOG4105CZN	Potassium uptake protein
CW735_07605	ENOG4105E5H	Transposase
CW735_07610	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CW735_07615	ENOG4105BZS	acriflavin resistance protein
CW735_07635	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CW735_07660	ENOG4105C8Q	Methyl-accepting chemotaxis
CW735_07680	ENOG4105EWK	phytoene
CW735_07700	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
CW735_07705	ENOG4105BZU	Histidine kinase
CW735_07710	ENOG4108I6A	alcohol dehydrogenase
CW735_07720	ENOG4108W5M	transcriptional regulator
CW735_07735	ENOG4105C8Q	Methyl-accepting chemotaxis
CW735_07780	ENOG4105K3G	Periplasmic Protein
CW735_07785	ENOG4105EKQ	RNA-directed DNA polymerase
CW735_07790	ENOG4105CGF	Aromatic amino acid aminotransferase
CW735_07805	ENOG4105C28	cystathionine
CW735_07820	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_07845	ENOG4108UKI	Enoyl-CoA hydratase
CW735_07850	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CW735_07855	ENOG4105KG3	cytidine deaminase
CW735_07875	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CW735_07880	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
CW735_07885	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CW735_07895	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
CW735_07900	ENOG4105BZ1	(ABC) transporter
CW735_07905	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CW735_07910	ENOG4105W49	UPF0434 protein
CW735_07915	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CW735_07920	ENOG4108RU0	short-chain dehydrogenase reductase
CW735_07925	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CW735_07945	ENOG4105CUZ	uba thif-type nad fad binding protein
CW735_07950	ENOG4105CHF	Glutathione S-transferase
CW735_07955	ENOG4105EUB	pirin domain protein
CW735_07965	ENOG4105BZN	citrate synthase
CW735_07970	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
CW735_07975	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
CW735_07980	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CW735_07985	ENOG4105E33	succinate dehydrogenase
CW735_07990	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CW735_07995	ENOG4105C7S	Dehydrogenase
CW735_08000	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CW735_08005	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CW735_08030	ENOG4108NRW	Phospholipase, patatin family
CW735_08050	ENOG4108IUK	alpha amylase, catalytic
CW735_08065	ENOG4105ETE	Transcriptional regulator (LacI family
CW735_08070	ENOG4105CX6	glutaminyL-tRNA synthetase
CW735_08075	ENOG4105UBK	short-chain dehydrogenase reductase
CW735_08080	ENOG4108M0H	Extracellular lipase
CW735_08085	ENOG4105ERU	peptidase
CW735_08095	ENOG4107QNR	UPF0135 protein
CW735_08100	ENOG4106371	Methyltransferase
CW735_08105	ENOG4105C5I	Dehydrogenase
CW735_08115	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CW735_08125	ENOG4105C1G	acyl-Coa dehydrogenase
CW735_08130	ENOG4108UKI	Enoyl-CoA hydratase
CW735_08135	ENOG4105DHI	Methyltransferase
CW735_08140	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CW735_08145	ENOG4105E68	Sulfatase
CW735_08150	ENOG4105YDX	UPF0352 protein
CW735_08155	ENOG4106V8H	Nucleoid-associated protein
CW735_08165	ENOG4105DR5	peptidase
CW735_08185	ENOG4108HRK	Histidine kinase
CW735_08190	ENOG4108VAC	response regulator
CW735_08195	ENOG4105CTQ	phosphohexokinase
CW735_08205	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CW735_08215	ENOG4105C72	UPF0176 protein
CW735_08225	ENOG4105C1J	atp-dependent rna helicase
CW735_08230	ENOG4107QNJ	CoA-transferase subunit B
CW735_08235	ENOG4105D6N	CoA-transferase, subunit a
CW735_08240	ENOG4105F04	LysR family Transcriptional regulator
CW735_08255	ENOG4107R11	Transcriptional regulator
CW735_08260	ENOG4105EJQ	L-serine dehydratase
CW735_08270	ENOG4105CRQ	synthase (Component I)
CW735_08280	ENOG4105CGY	Dna recombination protein
CW735_08300	ENOG4105CPP	Dehydrogenase, E1 component
CW735_08310	ENOG4105D6S	protein involved in catabolism of external DNA
CW735_08320	ENOG4105C29	acyl-CoA thioesterase
CW735_08325	ENOG4108Z0R	Transferase
CW735_08330	ENOG4105C5R	Aminotransferase
CW735_08340	ENOG4108ZGC	gaf domain protein
CW735_08350	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
CW735_08355	ENOG4105CN1	protease
CW735_08360	ENOG4105C8J	)-transporter
CW735_08365	ENOG4105DFD	Na H antiporter
CW735_08370	ENOG4105CD8	aminopeptidase N
CW735_08385	ENOG4105D25	secreted protein
CW735_08400	ENOG4105C7I	Dehydrogenase
CW735_08405	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CW735_08410	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CW735_08420	ENOG4105C5H	ABC transporter
CW735_08430	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
CW735_08435	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_08440	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CW735_08450	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CW735_08455	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CW735_08460	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CW735_08465	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CW735_08480	ENOG4105DFD	Na H antiporter
CW735_08505	ENOG4105GR3	Histidine kinase
CW735_08510	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CW735_08535	ENOG4108IJF	Heavy metal efflux pump, CzcA
CW735_08580	ENOG4105CHR	reductase
CW735_08605	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CW735_08620	ENOG4107JPU	
CW735_08635	ENOG4105C59	p-type ATPase
CW735_08665	ENOG4105D82	Glutamate dehydrogenase
CW735_08715	ENOG4108VSE	mercuric transport protein
CW735_08730	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CW735_08760	ENOG4105VW4	glutaredoxin 3
CW735_08775	ENOG4105VR0	copper resistance
CW735_08780	ENOG4105E3B	Multicopper oxidase
CW735_08805	ENOG41063TF	transcriptional regulator (AraC
CW735_08810	ENOG4105W1Y	Transcriptional regulator
CW735_08840	ENOG41080HT	Transcriptional regulator, arsr family
CW735_08905	ENOG4105PGM	cation diffusion facilitator family transporter
CW735_08960	ENOG4105CAH	Chromate
CW735_09105	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CW735_09115	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CW735_09120	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CW735_09125	ENOG4105C8V	SAICAR synthetase
CW735_09135	ENOG4105BZU	Histidine kinase
CW735_09145	ENOG4105BZU	Histidine kinase
CW735_09160	ENOG4105XPH	Ferredoxin
CW735_09165	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CW735_09170	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CW735_09175	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CW735_09180	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CW735_09185	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CW735_09190	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CW735_09195	ENOG4105CAT	Cytidine monophosphate kinase
CW735_09200	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CW735_09205	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CW735_09225	ENOG4105Q4A	inner membrane protein yciS
CW735_09230	ENOG4105CFV	Tetratricopeptide repeat protein
CW735_09235	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CW735_09240	ENOG4105DCF	alanine dehydrogenase
CW735_09245	ENOG4105EW9	transcriptional regulator AsnC family
CW735_09250	ENOG4105CNU	cell division protein FtsK
CW735_09255	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CW735_09260	ENOG4105D1H	recombination factor protein RarA
CW735_09265	ENOG4105WMR	Protein CrcB homolog
CW735_09270	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CW735_09280	ENOG4105BZU	Histidine kinase
CW735_09285	ENOG4105BZU	Histidine kinase
CW735_09295	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CW735_09300	ENOG4105BZU	Histidine kinase
CW735_09415	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
CW735_09430	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
CW735_09435	ENOG4108MN8	Membrane
CW735_09450	ENOG4105CC0	LysR family Transcriptional regulator
CW735_09455	ENOG4108VGI	doxx family
CW735_09480	ENOG4105WH1	Two component transcriptional regulator luxr family
CW735_09485	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CW735_09520	ENOG4108M8H	domain protein
CW735_09525	ENOG4106IUH	DTW domain containing protein
CW735_09530	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CW735_09535	ENOG4105KHC	sulfurtransferase
CW735_09540	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CW735_09565	ENOG4105D78	K07001 NTE family protein
CW735_09570	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CW735_09575	ENOG4105Q9Y	Universal stress protein
CW735_09605	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CW735_09620	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CW735_09640	ENOG4108UQY	Iron-storage protein
CW735_09645	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CW735_09650	ENOG4105CBC	glutamate synthase
CW735_09660	ENOG41081QV	Universal stress protein
CW735_09710	ENOG410600T	transposase
CW735_09715	ENOG4105F2I	Transposase
CW735_09740	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CW735_09790	ENOG4105E0K	tonB-dependent siderophore receptor
CW735_09870	ENOG4105ERG	peptidase m48, ste24p
CW735_09880	ENOG4105K89	arsenate reductase
CW735_09885	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CW735_09895	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
CW735_09905	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CW735_09910	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CW735_09920	ENOG4107QPN	acyl-Coa dehydrogenase
CW735_09930	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CW735_09935	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CW735_09940	ENOG4105DBI	uridine monophosphokinase
CW735_09945	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
CW735_09950	ENOG4105C3Q	Glycosyl transferase, family 2
CW735_09965	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CW735_09970	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CW735_09975	ENOG4107QI1	Mate efflux family protein
CW735_09990	ENOG4105C6T	cysteine synthase
CW735_10010	ENOG4105VFU	Rna-binding protein
CW735_10015	ENOG4107ZY0	Phenazine biosynthesis-like protein
CW735_10040	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CW735_10055	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CW735_10065	ENOG4105CK7	Sodium proline symporter
CW735_10080	ENOG4108KP7	hydrolase
CW735_10085	ENOG4105CHR	reductase
CW735_10115	ENOG4105BZU	Histidine kinase
CW735_10135	ENOG4105CP7	Triose-phosphate isomerase
CW735_10140	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CW735_10145	ENOG4105EEI	dihydropteroate synthase
CW735_10150	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CW735_10155	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CW735_10160	ENOG4105HBR	Rna-binding protein
CW735_10170	ENOG4105DAN	ATP-dependent protease
CW735_10175	ENOG4105C8T	Leucyl-tRNA synthetase
CW735_10190	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CW735_10195	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CW735_10200	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CW735_10205	ENOG4105CJN	penicillin-binding protein
CW735_10210	ENOG4105CNI	cell division protein FtsW
CW735_10215	ENOG4105K6T	rare lipoprotein A
CW735_10220	ENOG4105DZ1	carboxypeptidase
CW735_10225	ENOG4108Z43	UPF0250 protein
CW735_10230	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CW735_10235	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CW735_10250	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_10255	ENOG4105HDK	L-asparaginase
CW735_10265	ENOG41069NU	Nitroreductase
CW735_10280	ENOG4105D07	Signal peptide peptidase, SppA
CW735_10285	ENOG4105GPY	SprT protein
CW735_10290	ENOG4105PQ6	UPF0208 membrane protein
CW735_10295	ENOG4105C3M	thioredoxin reductase
CW735_10300	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CW735_10305	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CW735_10310	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CW735_10315	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CW735_10320	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CW735_10325	ENOG4105VEQ	Cold shock protein
CW735_10330	ENOG4105CSR	polyphosphate kinase 2
CW735_10335	ENOG4105E9K	Isocitrate dehydrogenase
CW735_10340	ENOG4108R99	pseudouridine synthase
CW735_10345	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CW735_10350	ENOG41075W9	High frequency lysogenization protein HflD homolog
CW735_10355	ENOG4107QTF	adenylosuccinate lyase
CW735_10360	ENOG4105EZE	Cupin 4 family protein
CW735_10375	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CW735_10380	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CW735_10385	ENOG4107RDJ	Sulfotransferase
CW735_10395	ENOG4105C94	Transporter
CW735_10405	ENOG4105VDB	UPF0125 protein
CW735_10410	ENOG4108Z1B	Cyclase dehydrase
CW735_10415	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CW735_10420	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CW735_10430	ENOG4105DFP	Integrase
CW735_10445	ENOG4106IJN	integrase catalytic domain-containing protein
CW735_10450	ENOG4105F5W	AtP-binding protein
CW735_10510	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CW735_10515	ENOG4105F27	Major Facilitator
CW735_10535	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
CW735_10540	ENOG4108VGW	abc transporter atp-binding protein
CW735_10550	ENOG4105VNH	ABC transporter solute-binding protein
CW735_10560	ENOG4107QN2	dihydrolipoyl dehydrogenase
CW735_10580	ENOG4105CCT	upf0313 protein
CW735_10615	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CW735_10620	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_10630	ENOG4105D3R	alkyl hydroperoxide reductase
CW735_10650	ENOG4105D0M	Protease HtpX homolog
CW735_10695	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
CW735_10705	ENOG4105FE9	pseudouridine synthase
CW735_10710	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CW735_10715	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CW735_10720	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CW735_10725	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CW735_10730	ENOG4105CHV	Transcription elongation factor NusA
CW735_10735	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CW735_10740	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CW735_10745	ENOG4105BZU	Histidine kinase
CW735_10750	ENOG4106IJN	integrase catalytic domain-containing protein
CW735_10755	ENOG4105F5W	AtP-binding protein
CW735_10775	ENOG4105KZX	Pterin carbinolamine dehydratase
CW735_10780	ENOG4105D05	Receptor
CW735_10810	ENOG4105D74	hydrolase
CW735_10815	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_10820	ENOG4105CSU	acyl-Coa dehydrogenase
CW735_10825	ENOG4105CHU	acetyl-coa acetyltransferase
CW735_10830	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CW735_10835	ENOG4108J2P	Alpha beta hydrolase fold
CW735_10845	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_10850	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CW735_10880	ENOG4105D4P	Coproporphyrinogen iii oxidase
CW735_10885	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CW735_10890	ENOG4105E0C	molybdate abc transporter
CW735_10895	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CW735_10900	ENOG4108ZAF	Molybdopterin
CW735_10905	ENOG4105M00	molybdopterin converting factor, subunit 1
CW735_10910	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CW735_10915	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CW735_10920	ENOG4105D06	uba thif-type nad fad binding protein
CW735_10925	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_10955	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_10975	ENOG4105EG6	Saccharopine dehydrogenase
CW735_11005	ENOG4107QYX	exodeoxyribonuclease v alpha
CW735_11010	ENOG4107QKA	exodeoxyribonuclease V beta
CW735_11015	ENOG4105DSY	exodeoxyribonuclease V, gamma
CW735_11030	ENOG4108IQE	Amp-dependent synthetase and ligase
CW735_11035	ENOG4105BZU	Histidine kinase
CW735_11075	ENOG4107RSM	transcriptional regulator
CW735_11080	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CW735_11100	ENOG4105BZU	Histidine kinase
CW735_11130	ENOG4105DK2	UPF0207 protein
CW735_11155	ENOG4105VUT	cytoplasmic protein
CW735_11165	ENOG4105BZG	amino acid carrier protein
CW735_11185	ENOG4105E0X	reductase
CW735_11190	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CW735_11200	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CW735_11205	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
CW735_11215	ENOG4105DSB	aldose 1-epimerase
CW735_11220	ENOG4108UHU	Aldolase
CW735_11225	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CW735_11230	ENOG4105C01	Dihydroxy-acid dehydratase
CW735_11235	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CW735_11240	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CW735_11245	ENOG4106KNT	transcriptional regulator
CW735_11250	ENOG4105CA9	Pyruvate kinase
CW735_11255	ENOG4105EKQ	RNA-directed DNA polymerase
CW735_11270	ENOG4105EKQ	RNA-directed DNA polymerase
CW735_11275	ENOG4108YYD	acetyltransferase
CW735_11345	ENOG4108UPT	UPF0178 protein
CW735_11350	ENOG4105CHR	reductase
CW735_11355	ENOG4105CHR	reductase
CW735_11360	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CW735_11365	ENOG4105CSU	acyl-Coa dehydrogenase
CW735_11370	ENOG4105FTV	AraC Family Transcriptional Regulator
CW735_11405	ENOG4105C10	Electron transfer flavoprotein
CW735_11410	ENOG4105BZJ	Electron transfer flavoprotein
CW735_11415	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CW735_11425	ENOG4105EV9	Alpha Beta Hydrolase
CW735_11435	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CW735_11445	ENOG41090R7	Ferric uptake
CW735_11465	ENOG4105E7W	lamb ycsf family protein
CW735_11470	ENOG4105QNR	S1 RNA binding domain protein
CW735_11475	ENOG4108UKZ	OsmC family
CW735_11480	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CW735_11505	ENOG4105CHM	Aminotransferase
CW735_11510	ENOG4105DK2	UPF0207 protein
CW735_11515	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CW735_11525	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CW735_11530	ENOG4105W39	Membrane
CW735_11555	ENOG4105BZU	Histidine kinase
CW735_11570	ENOG4105F8V	Hydrolase, tatD family
CW735_11575	ENOG4107QRG	dna polymerase iii
CW735_11580	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CW735_11585	ENOG4105HHA	aminodeoxychorismate lyase
CW735_11590	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
CW735_11595	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CW735_11600	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CW735_11605	ENOG4105CHR	reductase
CW735_11610	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CW735_11615	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CW735_11620	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CW735_11625	ENOG4105VGS	50s ribosomal protein l32
CW735_11630	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CW735_11645	ENOG4105EI2	Pseudouridine synthase
CW735_11650	ENOG4105C03	ribonuclease
CW735_11655	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_11665	ENOG4105BZU	Histidine kinase
CW735_11680	ENOG4105C26	Dehydrogenase
CW735_11685	ENOG41086D8	Transcriptional regulator
CW735_11690	ENOG4107YB6	acetyltransferase, (GNAT) family
CW735_11700	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CW735_11705	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
CW735_11720	ENOG4105CK2	sodium dicarboxylate symporter
CW735_11725	ENOG4105D60	lipoprotein releasing system transmembrane protein
CW735_11730	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CW735_11735	ENOG4108M8H	domain protein
CW735_11765	ENOG4108JDX	DNA polymerase iii, epsilon subunit
CW735_11770	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CW735_11775	ENOG4108JA1	polyketide synthase
CW735_11780	ENOG4105DR4	Methyltransferase
CW735_11795	ENOG4105CQ7	ATP-dependent helicase
CW735_11810	ENOG4105CJB	Exodeoxyribonuclease I
CW735_11835	ENOG4105CHU	acetyl-coa acetyltransferase
CW735_11840	ENOG4108Z6Z	Transcriptional regulator
CW735_11845	ENOG4105C1G	acyl-Coa dehydrogenase
CW735_11850	ENOG4107QX3	carboxylase
CW735_11865	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CW735_11890	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CW735_11900	ENOG4105DNH	Major Facilitator
CW735_11935	ENOG4105CGK	Exodeoxyribonuclease III
CW735_11960	ENOG4105D60	lipoprotein releasing system transmembrane protein
CW735_11970	ENOG4108JA2	transcriptioN-repair coupling factor
CW735_11980	ENOG4108WBT	adenosyltransferase
CW735_12015	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CW735_12025	ENOG4108Z66	YbaK ebsC protein
CW735_12035	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CW735_12040	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CW735_12045	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CW735_12050	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CW735_12055	ENOG41082NX	50s ribosomal protein l35
CW735_12060	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CW735_12065	ENOG4105C22	threonyL-tRNA synthetase
CW735_12075	ENOG4105CHR	reductase
CW735_12090	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CW735_12095	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CW735_12100	ENOG4105HF0	Membrane
CW735_12105	ENOG4105C5R	Aminotransferase
CW735_12120	ENOG4105C2W	permease
CW735_12135	ENOG4105BZU	Histidine kinase
CW735_12150	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CW735_12155	ENOG4105C7N	Xanthine uracil vitamin C permease
CW735_12170	ENOG4108R86	Transcriptional regulator
CW735_12180	ENOG4105C7W	Xanthine dehydrogenase
CW735_12200	ENOG4107QUY	Guanine deaminase
CW735_12210	ENOG4105BZU	Histidine kinase
CW735_12215	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CW735_12220	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CW735_12225	ENOG4105BZU	Histidine kinase
CW735_12230	ENOG4105BZU	Histidine kinase
CW735_12235	ENOG4105CH2	amidohydrolase
CW735_12240	ENOG4105DP0	ferredoxin-NADP reductase
CW735_12245	ENOG4107QQR	Sporulation
CW735_12255	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CW735_12260	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CW735_12280	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CW735_12380	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
CW735_12385	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CW735_12410	ENOG4105KUZ	arsenate reductase
CW735_12415	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CW735_12430	ENOG4105K8R	UPF0145 protein
CW735_12440	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
CW735_12455	ENOG4105BZU	Histidine kinase
CW735_12460	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CW735_12465	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CW735_12470	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
CW735_12475	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CW735_12485	ENOG4105F8C	transglutaminase domain-containing protein
CW735_12505	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CW735_12510	ENOG4105M08	Membrane
CW735_12520	ENOG4105ETT	transcriptional Regulator, LysR family
CW735_12530	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CW735_12535	ENOG4108YY7	Invasion gene expression up-regulator SirB
CW735_12540	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CW735_12545	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CW735_12550	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CW735_12555	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CW735_12560	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
CW735_12565	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CW735_12575	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CW735_12580	ENOG41067V2	Esterase lipase
CW735_12585	ENOG4105DQ4	alcohol dehydrogenase
CW735_12595	ENOG4105DQ4	alcohol dehydrogenase
CW735_12600	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CW735_12605	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CW735_12610	ENOG4105C3G	gtp-binding protein
CW735_12615	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CW735_12655	ENOG4105BZG	amino acid carrier protein
CW735_12670	ENOG41072GX	Peptidase M22 Glycoprotease
CW735_12675	ENOG4105DVT	helicase
CW735_12710	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CW735_12715	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CW735_12720	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CW735_12725	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CW735_12730	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CW735_12735	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CW735_12740	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CW735_12745	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CW735_12755	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CW735_12760	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CW735_12765	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CW735_12775	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CW735_12780	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CW735_12785	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CW735_12795	ENOG4105E18	UPF0276 protein
CW735_12855	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CW735_12875	ENOG4105CXG	d-lactate dehydrogenase
CW735_12880	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_12895	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CW735_12900	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CW735_12905	ENOG4105C34	Pseudouridine synthase
CW735_12910	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CW735_12920	ENOG4105K6V	RNA polymerase
CW735_12935	ENOG4105EMU	Dehydrogenase
CW735_12950	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CW735_12955	ENOG4106VK6	Flagellar motor protein
CW735_12960	ENOG4105E14	MotA TolQ exbB proton channel
CW735_12965	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CW735_12970	ENOG4105CTB	Polyprenyl synthetase
CW735_12975	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CW735_12980	ENOG4108ZAI	phosphatidylglycerophosphatase a
CW735_12985	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CW735_12990	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CW735_12995	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CW735_13010	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CW735_13015	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CW735_13020	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CW735_13025	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CW735_13030	ENOG4105C5H	ABC transporter
CW735_13040	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CW735_13050	ENOG4105EAC	phosphoserine phosphatase
CW735_13060	ENOG4105EYA	deoxyribonuclease
CW735_13065	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CW735_13080	ENOG4105C3F	Signal peptidase i
CW735_13085	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CW735_13095	ENOG4105VQK	sigma E regulatory protein, MucB RseB
CW735_13105	ENOG4105EMN	RNA polymerase sigma factor
CW735_13110	ENOG4108IYU	L-aspartate oxidase
CW735_13120	ENOG4105Y75	tpr repeat protein
CW735_13125	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CW735_13130	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CW735_13135	ENOG4108YZA	Nitrogen regulatory protein pii
CW735_13140	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
CW735_13160	ENOG4105JCS	prepilin peptidase dependent protein
CW735_13200	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_13205	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CW735_13210	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CW735_13215	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CW735_13220	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CW735_13225	ENOG4105DTN	riboflavin biosynthesis protein ribF
CW735_13230	ENOG4105CJR	Integral membrane protein (MviN
CW735_13235	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CW735_13250	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CW735_13260	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_13265	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CW735_13275	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CW735_13280	ENOG4105K70	DNA-binding protein
CW735_13285	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CW735_13290	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CW735_13295	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CW735_13300	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CW735_13330	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CW735_13340	ENOG4108R96	Methyltransferase, YaeB family
CW735_13345	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CW735_13350	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CW735_13355	ENOG4105HDD	phospholipase
CW735_13360	ENOG4105DGU	Histone deacetylase
CW735_13365	ENOG4108NVR	Methyl-accepting chemotaxis
CW735_13375	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CW735_13380	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CW735_13385	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CW735_13395	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CW735_13400	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CW735_13405	ENOG4105N21	Membrane
CW735_13410	ENOG4105CUT	histidyl-tRNA synthetase
CW735_13415	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CW735_13425	ENOG41090FY	type IV pilus biogenesis stability protein PilW
CW735_13430	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CW735_13435	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CW735_13440	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CW735_13450	ENOG4108Z4V	iron-sulfur cluster assembly
CW735_13455	ENOG4105C9B	Cysteine desulfurase
CW735_13460	ENOG4105JRK	feS assembly protein SufD
CW735_13465	ENOG4105C3K	feS assembly ATPase SufC
CW735_13475	ENOG4105C3J	Cysteine desulfurase
CW735_13480	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CW735_13500	ENOG4105CT3	Monooxygenase
CW735_13510	ENOG4105D7W	serine acetyltransferase
CW735_13515	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
CW735_13525	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CW735_13530	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CW735_13535	ENOG4105VIE	preprotein translocase, subunit YajC
CW735_13540	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CW735_13545	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CW735_13560	ENOG4108P9J	Phage shock protein A
CW735_13585	ENOG4106032	Glutathionylspermidine synthase
CW735_13600	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CW735_13620	ENOG4105CSV	Glutaminase
CW735_13625	ENOG4105G6Z	alkaline phosphatase
CW735_13635	ENOG4107RET	Isocitrate lyase
CW735_13720	ENOG4108UW5	maltose o-acetyltransferase
CW735_13755	ENOG4105CAQ	asparagine synthetase
CW735_13765	ENOG4105JNK	Glycosyl transferase (Group 1
CW735_13840	ENOG4105D3Q	Sugar transferase
CW735_13855	ENOG4108QV3	biosynthesis protein
CW735_13870	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CW735_13885	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CW735_13895	ENOG4105D1S	lipid A biosynthesis
CW735_13925	ENOG4107QPN	acyl-Coa dehydrogenase
CW735_13940	ENOG4105BZU	Histidine kinase
CW735_13945	ENOG4107104	thymidine kinase
CW735_13955	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CW735_13965	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_13970	ENOG4105D7V	transposase
CW735_13985	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CW735_13990	ENOG4108RWN	rrna methyltransferase
CW735_14010	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
CW735_14045	ENOG4105CSU	acyl-Coa dehydrogenase
CW735_14060	ENOG4107T0K	Adenylate cyclase
CW735_14065	ENOG4107XDR	Lactoylglutathione lyase
CW735_14085	ENOG4105EMU	Dehydrogenase
CW735_14090	ENOG410829K	Lysine exporter protein (Lyse ygga)
CW735_14120	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CW735_14180	ENOG4107R4I	Periplasmic binding protein
CW735_14185	ENOG4105EHG	Permease protein
CW735_14190	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CW735_14205	ENOG4108ISG	Major Facilitator
CW735_14220	ENOG4108VWS	Yaeq family
CW735_14225	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CW735_14230	ENOG4107U9T	Pfam:Ribonuclease_BN
CW735_14235	ENOG4105BZU	Histidine kinase
CW735_14265	ENOG4105D8V	Glucose sorbosone dehydrogenase
CW735_14270	ENOG4105C1J	atp-dependent rna helicase
CW735_14305	ENOG4105PWE	CRISPR-associated protein cas2
CW735_14310	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
CW735_14325	ENOG4108VWQ	crispr-associated protein
CW735_14345	ENOG4105DTT	CRISPR-associated helicase, cas3
CW735_14355	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CW735_14360	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CW735_14365	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CW735_14370	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_14390	ENOG4105CE4	GlcNAc 6-P deacetylase
CW735_14400	ENOG4105DC7	peptidase M24
CW735_14405	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CW735_14410	ENOG4105D0A	hydroxylase
CW735_14415	ENOG4107RAQ	aminopeptidase
CW735_14430	ENOG4108RVA	ribokinase
CW735_14440	ENOG4105BZU	Histidine kinase
CW735_14445	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CW735_14450	ENOG4105E66	phosphoriboisomerase A
CW735_14455	ENOG4108JQ1	Dehydrogenase
CW735_14510	ENOG4107QN2	dihydrolipoyl dehydrogenase
CW735_14515	ENOG4107QSN	dihydrolipoamide acetyltransferase
CW735_14520	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CW735_14525	ENOG41073TP	transcriptional regulator
CW735_14535	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CW735_14540	ENOG4108WIW	Aspartyl protease
CW735_14545	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CW735_14555	ENOG4105D7Q	type ii secretion system
CW735_14565	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CW735_14570	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
CW735_14575	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CW735_14580	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
CW735_14585	ENOG4105M6F	mutator MutT protein
CW735_14590	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CW735_14595	ENOG4105DR5	peptidase
CW735_14600	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CW735_14605	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CW735_14610	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CW735_14615	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CW735_14620	ENOG4105CPF	Cell wall formation (By similarity)
CW735_14625	ENOG4105DFU	Cell wall formation (By similarity)
CW735_14630	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CW735_14635	ENOG4105CNI	cell division protein FtsW
CW735_14640	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CW735_14645	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CW735_14650	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CW735_14655	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CW735_14660	ENOG4105CJN	penicillin-binding protein
CW735_14665	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CW735_14670	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CW735_14675	ENOG4108V6E	Cell division protein mraZ
CW735_14695	ENOG4105EHV	domain protein
CW735_14710	ENOG4105BZU	Histidine kinase
CW735_14725	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CW735_14730	ENOG4105BZU	Histidine kinase
CW735_14765	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CW735_14775	ENOG4108UJU	UPF0301 protein
CW735_14780	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CW735_14790	ENOG4105CZX	twitching motility protein
CW735_14795	ENOG4105CZX	twitching motility protein
CW735_14800	ENOG4105DFA	alanine racemase domain protein
CW735_14805	ENOG4105II7	pyrroline-5-carboxylate reductase
CW735_14810	ENOG4108VIA	integral membrane protein
CW735_14820	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CW735_14830	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_14840	ENOG4105D1Q	UPF0246 protein
CW735_14845	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CW735_14850	ENOG4107QP8	phosphohexose isomerase
CW735_14860	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CW735_14870	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CW735_14880	ENOG4105CC0	LysR family Transcriptional regulator
CW735_14895	ENOG41082YX	Transcriptional regulator, arsr family
CW735_14905	ENOG4105CAU	Arsenical resistance protein, ArsH
CW735_14910	ENOG4105D6J	arsenicaL-resistance protein
CW735_14920	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
CW735_14925	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CW735_14935	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CW735_14960	ENOG4105E3Q	saccharopine dehydrogenase
CW735_14975	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CW735_14980	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
CW735_14985	ENOG41082RQ	UPF0102 protein
CW735_14990	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CW735_14995	ENOG4105W4M	Transport-associated protein
CW735_15025	ENOG4105W4C	monovalent cation H antiporter subunit F
CW735_15030	ENOG4105SC1	monovalent cation H antiporter subunit E
CW735_15035	ENOG4107R4Z	monovalent cation h antiporter subunit d
CW735_15040	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CW735_15045	ENOG4105D65	subunit l
CW735_15070	ENOG4105CR4	methylisocitrate lyase
CW735_15075	ENOG4105BZN	citrate synthase
CW735_15080	ENOG4108I0Z	Aconitate hydratase
CW735_15085	ENOG4105C7F	AcnD-accessory protein PrpF
CW735_15090	ENOG4105BZU	Histidine kinase
CW735_15110	ENOG4105BZU	Histidine kinase
CW735_15115	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CW735_15120	ENOG4105CBC	glutamate synthase
CW735_15125	ENOG4105BZ8	glutamate synthase
CW735_15135	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CW735_15145	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CW735_15155	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CW735_15160	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CW735_15175	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CW735_15180	ENOG4105DR5	peptidase
CW735_15185	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CW735_15190	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CW735_15195	ENOG4105WS7	Cation transport regulator
CW735_15210	ENOG4105C5I	Dehydrogenase
CW735_15215	ENOG4108U78	Glutathione S-transferase
CW735_15220	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CW735_15225	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CW735_15230	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CW735_15235	ENOG4107QMS	site-determining protein
CW735_15240	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CW735_15245	ENOG4105C9Q	fumarate hydratase class II
CW735_15280	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CW735_15285	ENOG4105C87	Aminotransferase class I and II
CW735_15300	ENOG4105C5F	glutamine synthetase
CW735_15310	ENOG4105CUX	Signal transduction histidine kinase
CW735_15315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CW735_15320	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CW735_15325	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
CW735_15330	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
CW735_15345	ENOG4105BZU	Histidine kinase
CW735_15350	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CW735_15355	ENOG4105MYG	DNA polymerase iii, chi subunit
CW735_15360	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CW735_15365	ENOG4108M8S	permease YjgP YjgQ family protein
CW735_15370	ENOG4108K5H	permease YjgP YjgQ family protein
CW735_15380	ENOG4105K6V	RNA polymerase
CW735_15415	ENOG4105EDR	glucose galactose transporter
CW735_15435	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CW735_15460	ENOG4105DZR	Type I site-specific deoxyribonuclease
CW735_15465	ENOG4105EKX	Restriction modification system DNA (Specificity
CW735_15470	ENOG4105CVR	type I restriction-modification system
CW735_15505	ENOG4108B1Q	Ribonuclease
CW735_15570	ENOG4105I03	Flagellin
CW735_15600	ENOG4105F5W	AtP-binding protein
CW735_15605	ENOG4106IJN	integrase catalytic domain-containing protein
CW735_15730	ENOG4105BZU	Histidine kinase
CW735_15760	ENOG4105VFE	sira family
CW735_15795	ENOG4105EG6	Saccharopine dehydrogenase
CW735_15800	ENOG4105C1G	acyl-Coa dehydrogenase
CW735_15830	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CW735_15835	ENOG4105BZU	Histidine kinase
CW735_15850	ENOG4105C26	Dehydrogenase
CW735_15855	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CW735_15860	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_15885	ENOG4105CXG	d-lactate dehydrogenase
CW735_15895	ENOG4105C1J	atp-dependent rna helicase
CW735_15905	ENOG4105EGS	Mechanosensitive ion channel
CW735_15915	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_15925	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CW735_15945	ENOG4105DND	Transcriptional regulator
CW735_15950	ENOG4105HF0	Membrane
CW735_15955	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CW735_15960	ENOG4107QQR	Sporulation
CW735_15970	ENOG4105BZU	Histidine kinase
CW735_16025	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CW735_16030	ENOG4105EJ2	Transcriptional regulator
CW735_16040	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
CW735_16050	ENOG4108RG0	uracil-dna glycosylase
CW735_16055	ENOG4105BZU	Histidine kinase
CW735_16065	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CW735_16070	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CW735_16075	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CW735_16100	ENOG41087YS	Phage shock protein A
CW735_16110	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CW735_16185	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
CW735_16190	ENOG4107XZC	Restriction modification system DNA (Specificity
CW735_16200	ENOG4108HFV	
CW735_16250	ENOG4105CAF	HipA N-terminal domain protein
CW735_16265	ENOG4105C4W	S-formylglutathione hydrolase
CW735_16270	ENOG4106HNH	Acyl-transferase
CW735_16275	ENOG4106HNH	Acyl-transferase
CW735_16280	ENOG4105CUY	Mechanosensitive ion channel
CW735_16295	ENOG4108535	NAD dependent epimerase/dehydratase family
CW735_16300	ENOG4105C8J	)-transporter
CW735_16315	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CW735_16330	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
CW735_16340	ENOG4109015	Biopolymer transport protein exbD tolR
CW735_16355	ENOG4105EJG	cellulose synthase
CW735_16360	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
CW735_16370	ENOG4107QZ7	Cellulose synthase catalytic subunit
CW735_16385	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CW735_16400	ENOG4105KWG	Pfam:DUF1696
CW735_16405	ENOG4105BZU	Histidine kinase
CW735_16415	ENOG4105EFZ	amidohydrolase
CW735_16425	ENOG4105C5X	domain protein
CW735_16435	ENOG4108WAV	Transcriptional regulator
CW735_16440	ENOG4105E7A	Glutamine amidotransferase
CW735_16445	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CW735_16455	ENOG4105BZU	Histidine kinase
CW735_16470	ENOG4105C5X	domain protein
CW735_16480	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CW735_16490	ENOG4105CJ2	(LipO)protein
CW735_16495	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
CW735_16500	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CW735_16505	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CW735_16510	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CW735_16515	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CW735_16525	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_16530	ENOG4105RKW	reductase (By
CW735_16535	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CW735_16540	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CW735_16570	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CW735_16575	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CW735_16585	ENOG4108KPZ	tonB-dependent Receptor
CW735_16600	ENOG4105DBI	uridine monophosphokinase
CW735_16605	ENOG4105D9N	nucleoside
CW735_16625	ENOG4105BZU	Histidine kinase
CW735_16635	ENOG4105C2X	Arabinose 5-phosphate isomerase
CW735_16640	ENOG4107QN1	sodium solute
CW735_16650	ENOG4105BZU	Histidine kinase
CW735_16660	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CW735_16670	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CW735_16685	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CW735_16700	ENOG4105CPC	Aldo Keto reductase
CW735_16710	ENOG4105BZU	Histidine kinase
CW735_16730	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CW735_16755	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CW735_16760	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CW735_16765	ENOG4105D4A	Cell wall formation (By similarity)
CW735_16770	ENOG4107SDU	Methyl-accepting chemotaxis
CW735_16820	ENOG41063Z6	transcriptional regulator, lysR family
CW735_16830	ENOG4105D7V	transposase
CW735_16855	ENOG4107QK5	Homocysteine s-methyltransferase
CW735_16915	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CW735_16925	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CW735_16950	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CW735_16965	ENOG4105ESV	Glycosyl transferase, family 4
CW735_16995	ENOG4105E5H	Transposase
CW735_17045	ENOG4105F0R	Cytidylyltransferase
CW735_17050	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
CW735_17060	ENOG4105D2T	synthase
CW735_17065	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
CW735_17070	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CW735_17085	ENOG4107V1M	polysaccharide export protein
CW735_17090	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CW735_17110	ENOG4108VYJ	response regulator receiver protein
CW735_17115	ENOG4105I03	Flagellin
CW735_17120	ENOG4108ZT0	50S ribosomal protein l17
CW735_17125	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CW735_17130	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CW735_17135	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CW735_17140	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CW735_17150	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CW735_17155	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CW735_17160	ENOG4105VPB	50S ribosomal protein L30
CW735_17165	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CW735_17170	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CW735_17175	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CW735_17180	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CW735_17185	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CW735_17190	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CW735_17195	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CW735_17200	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CW735_17210	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_17225	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_17240	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CW735_17250	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CW735_17255	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CW735_17270	ENOG4105D7V	transposase
CW735_17280	ENOG4108UV7	flagellar protein motX
CW735_17290	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CW735_17295	ENOG4107QK7	reductase
CW735_17300	ENOG4107VAM	peptidase, m28
CW735_17310	ENOG4105BZU	Histidine kinase
CW735_17315	ENOG4105FCW	Major Facilitator superfamily
CW735_17325	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CW735_17330	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CW735_17335	ENOG4108XM1	transcriptional regulator AsnC family
CW735_17345	ENOG4105VEQ	Cold shock protein
CW735_17350	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CW735_17370	ENOG4105DGW	oligopeptidase A
CW735_17375	ENOG4107YTP	response regulator receiver protein
CW735_17385	ENOG4105BZU	Histidine kinase
CW735_17390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CW735_17395	ENOG4105DC8	reductase
CW735_17400	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CW735_17410	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
CW735_17455	ENOG4108MBX	Secretion Protein
CW735_17460	ENOG4108JJA	ABC, transporter
CW735_17465	ENOG4105WH1	Two component transcriptional regulator luxr family
CW735_17475	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CW735_17480	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CW735_17485	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CW735_17490	ENOG41063M6	Cell Division Protein
CW735_17495	ENOG4105C25	Primosomal protein n'
CW735_17500	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CW735_17510	ENOG4105C6K	Malic enzyme
CW735_17515	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
CW735_17520	ENOG4105SYT	Methylenetetrahydrofolate reductase
CW735_17525	ENOG4107S2Z	UPF0761 membrane protein
CW735_17545	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CW735_17550	ENOG4105SUU	thioesterase domain
CW735_17555	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CW735_17560	ENOG4105D58	Diguanylate phosphodiesterase
CW735_17565	ENOG4105D58	Diguanylate phosphodiesterase
CW735_17570	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CW735_17575	ENOG4105CAK	Cell division ATP-binding protein ftsE
CW735_17580	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CW735_17585	ENOG4106H78	methyltransferase
CW735_17590	ENOG4105R2J	Conserved Protein
CW735_17595	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CW735_17605	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CW735_17610	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CW735_17615	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CW735_17620	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CW735_17625	ENOG4105DJ0	Poly(A) Polymerase
CW735_17630	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CW735_17635	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CW735_17640	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CW735_17645	ENOG4105DY8	decarboxylase
CW735_17660	ENOG4105E3A	(ABC) transporter
CW735_17665	ENOG4105DA5	(ABC) transporter
CW735_17685	ENOG4107E2E	PKHD-type hydroxylase
CW735_17700	ENOG4105D22	carbon starvation protein
CW735_17725	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CW735_17730	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CW735_17735	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CW735_17740	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CW735_17745	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CW735_17750	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CW735_17755	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CW735_17760	ENOG4108VZM	50s ribosomal protein L10
CW735_17765	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CW735_17770	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CW735_17775	ENOG4105BZU	Histidine kinase
CW735_17785	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CW735_17790	ENOG4105PM1	preprotein translocase subunit SecE
CW735_17800	ENOG4105BZ1	(ABC) transporter
CW735_17820	ENOG4105JSC	dimethylmenaquinone methyltransferase
CW735_17825	ENOG4105C9K	Endothelin-converting enzyme 1
CW735_17835	ENOG4105C1J	atp-dependent rna helicase
CW735_17840	ENOG4105EKE	dihydroorotase
CW735_17850	ENOG4105QNF	Outer membrane lipoprotein
CW735_17855	ENOG4107RGM	aldo keto reductase
CW735_17860	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CW735_17865	ENOG4105DP8	Major facilitator superfamily MFS_1
CW735_17870	ENOG4107QW3	Sucrose phosphorylase
CW735_17880	ENOG4105EUJ	GTP cyclohydrolase i
CW735_17885	ENOG410642E	Short chain dehydrogenase
CW735_17890	ENOG4105DWY	Agmatine deiminase
CW735_17905	ENOG4107QRT	dEAD DEAH box helicase
CW735_17925	ENOG4107T0X	DNA ligase
CW735_17950	ENOG4105CYM	Glutathione S-transferase
CW735_17965	ENOG4107IFA	Lipase (EC 3.1.1.3)
CW735_17970	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CW735_17995	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CW735_18000	ENOG4105CFC	Transporter
CW735_18005	ENOG4105EPW	hflc protein
CW735_18010	ENOG4107QJR	hflk protein
CW735_18015	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CW735_18020	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CW735_18025	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CW735_18030	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CW735_18035	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CW735_18040	ENOG4105K8N	protein family UPF0079, ATPase
CW735_18045	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CW735_18060	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CW735_18065	ENOG4105E09	nadh pyrophosphatase
CW735_18070	ENOG4105MYN	Zinc uptake regulation protein
CW735_18080	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
CW735_18085	ENOG4105CDV	Ompa motb domain protein
CW735_18090	ENOG4105CDU	Replicative dna helicase
CW735_18125	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_18130	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CW735_18135	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CW735_18140	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CW735_18145	ENOG4105BZU	Histidine kinase
CW735_18155	ENOG4105C19	ABC transporter
CW735_18165	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
CW735_18170	ENOG4105BZU	Histidine kinase
CW735_18175	ENOG4105C8Q	Methyl-accepting chemotaxis
CW735_18185	ENOG4105PGM	cation diffusion facilitator family transporter
CW735_18195	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CW735_18225	ENOG4108ESX	Receptor
CW735_18245	ENOG41060NJ	transcriptional regulator
CW735_18250	ENOG4107QNK	)-transporter
CW735_18255	ENOG4108JJ8	(ABC) transporter
CW735_18260	ENOG4108JJ9	ABC, transporter
CW735_18270	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CW735_18275	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CW735_18285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CW735_18300	ENOG4105Q26	Siderophore-interacting protein
CW735_18305	ENOG4105VDW	Csbd family
CW735_18315	ENOG4108YZN	class I peptide chain release factor
CW735_18320	ENOG4108MUZ	hydrolase
CW735_18330	ENOG4105DS1	cytochrome b561
CW735_18335	ENOG4108YYC	ycei family
CW735_18340	ENOG4105CEP	NADH dehydrogenase
CW735_18360	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CW735_18370	ENOG4105BZU	Histidine kinase
CW735_18380	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CW735_18390	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CW735_18400	ENOG4105D9R	oxidoreductase
CW735_18405	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CW735_18415	ENOG4107RT3	EamA-like transporter family
CW735_18420	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CW735_18425	ENOG4105D03	DNA-3-methyladenine glycosylase II
CW735_18435	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CW735_18445	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CW735_18450	ENOG4105W8H	transhydrogenase (subunit alpha
CW735_18455	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CW735_18465	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
CW735_18475	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CW735_18480	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CW735_18490	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CW735_18500	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CW735_18505	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CW735_18510	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CW735_18515	ENOG4105EQR	Transposase IS116 IS110 IS902
CW735_18530	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CW735_18565	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CW735_18570	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CW735_18575	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CW735_18580	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CW735_18590	ENOG4105C12	Phosphoribosylglycinamide synthetase
CW735_18595	ENOG4105EYW	Ion transport protein
CW735_18615	ENOG41084S7	Plasmid maintenance system antidote protein
CW735_18650	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CW735_18660	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CW735_18665	ENOG4105E0F	Histidine kinase
CW735_18670	ENOG4105CJQ	hydrolase, family 31
CW735_18675	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CW735_18680	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CW735_18685	ENOG4105VEJ	Heat shock protein
CW735_18690	ENOG4108XKW	General secretion pathway protein C
CW735_18700	ENOG4107QHF	type ii secretion system protein e
CW735_18705	ENOG4105D7Q	type ii secretion system
CW735_18710	ENOG4108VAU	general secretion pathway protein G
CW735_18715	ENOG4105VWV	general secretion pathway protein h
CW735_18730	ENOG4108RTD	type II secretion system protein K
CW735_18770	ENOG4105C26	Dehydrogenase
CW735_18780	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
CW735_18785	ENOG4107RK2	ADP-ribose diphosphatase NudE
CW735_18790	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CW735_18800	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
CW735_18805	ENOG4105DJ9	glucan biosynthesis protein
CW735_18815	ENOG4105YP7	UPF0270 protein
CW735_18820	ENOG4105DNZ	Alpha Beta Hydrolase
CW735_18830	ENOG4105C5H	ABC transporter
CW735_18840	ENOG41069P5	Protein slyX homolog
CW735_18850	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CW735_18865	ENOG4108RRZ	Transcription elongation factor GreB
CW735_18870	ENOG4105BZM	domain protein
CW735_18885	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CW735_18890	ENOG4105MJ2	Competence protein
CW735_18900	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CW735_18920	ENOG4107R73	Mate efflux family protein
CW735_18935	ENOG4108ZX6	Electron transport protein SCO1 SenC
CW735_18940	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CW735_18945	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
CW735_18975	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CW735_18985	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CW735_19000	ENOG4105E55	glycerol-3-phosphate acyltransferase
CW735_19005	ENOG4105C7B	Threonine dehydratase
CW735_19010	ENOG4105C01	Dihydroxy-acid dehydratase
CW735_19015	ENOG4105EN6	Membrane
CW735_19020	ENOG4105C0P	Mg chelatase subunit ChlI
CW735_19025	ENOG4105EMY	transcriptional regulator
CW735_19030	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CW735_19045	ENOG4105C2C	drug resistance transporter, Bcr CflA
CW735_19050	ENOG4105V1F	Fermentation respiration switch protein
CW735_19055	ENOG4105CFU	surface antigen
CW735_19060	ENOG4105MA0	exported protein
CW735_19070	ENOG4105EMN	RNA polymerase sigma factor
CW735_19085	ENOG4105C5I	Dehydrogenase
CW735_19095	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CW735_19140	ENOG4105CI2	imidazolone-5-propionate hydrolase
CW735_19155	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CW735_19160	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CW735_19165	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CW735_19170	ENOG4105DSJ	YicC domain protein
CW735_19240	ENOG4105CFI	type iii restriction protein res subunit
CW735_19295	ENOG41060NJ	transcriptional regulator
CW735_19315	ENOG4105CDV	Ompa motb domain protein
CW735_19320	ENOG4105CPI	Metal Dependent Phosphohydrolase
CW735_19340	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CW735_19345	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CW735_19350	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CW735_19355	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CW735_19360	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CW735_19365	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CW735_19370	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CW735_19375	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CW735_19385	ENOG4105FA0	parb-like partition protein
CW735_19390	ENOG4107QJE	Chromosome Partitioning Protein
CW735_19395	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CW735_19400	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CW735_19415	ENOG4105QTB	Flavodoxin
CW735_19420	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CW735_19425	ENOG4108VPT	UPF0234 protein
CW735_19430	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CW735_19435	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CW735_19440	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CW735_19445	ENOG4105VG0	50S ribosomal protein l34