locus-tag	class	description
AV940_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AV940_00020	COG0187	DNA topoisomerase II activity
AV940_00045	COG2818	Glycosylase
AV940_00055	COG3078	GTPase activator activity
AV940_00070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV940_00070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AV940_00075	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AV940_00080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AV940_00085	COG0569	domain protein
AV940_00090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AV940_00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AV940_00110	COG0758	DNA mediated transformation
AV940_00125	COG0009	L-threonylcarbamoyladenylate synthase
AV940_00130	COG0408	coproporphyrinogen oxidase activity
AV940_00135	COG3047	cAMP biosynthetic process
AV940_00150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AV940_00205	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AV940_00225	COG2234	aminopeptidase activity
AV940_00240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AV940_00265	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV940_00305	COG3642	lipopolysaccharide core region biosynthetic process
AV940_00310	COG0859	PFAM glycosyl transferase family 9
AV940_00330	COG0156	8-amino-7-oxononanoate synthase activity
AV940_00340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV940_00345	COG0705	Rhomboid family
AV940_00355	COG3161	chorismate lyase activity
AV940_00360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AV940_00365	COG2960	long-chain fatty acid transporting porin activity
AV940_00370	COG0210	DNA helicase
AV940_00465	COG1620	l-lactate permease
AV940_00485	COG1902	pentaerythritol trinitrate reductase activity
AV940_00485	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV940_00505	COG4638	Rieske (2fe-2S)
AV940_00515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV940_00515	COG1017	nitric oxide dioxygenase activity
AV940_00520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AV940_00560	COG1760	l-serine dehydratase
AV940_00565	COG0583	DNA-binding transcription factor activity
AV940_00580	COG1012	belongs to the aldehyde dehydrogenase family
AV940_00585	COG4948	Mandelate Racemase Muconate Lactonizing
AV940_00595	COG1012	belongs to the aldehyde dehydrogenase family
AV940_00600	COG4771	TonB-dependent receptor
AV940_00605	COG0457	Tetratricopeptide repeat
AV940_00610	COG3437	response regulator, receiver
AV940_00610	COG3850	Histidine kinase
AV940_00610	COG4999	Histidine kinase
AV940_00610	COG2205	protein histidine kinase activity
AV940_00615	COG4773	Receptor
AV940_00620	COG0583	DNA-binding transcription factor activity
AV940_00635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV940_00640	COG0842	Transport permease protein
AV940_00640	COG1129	ABC transporter
AV940_00645	COG0842	Transport permease protein
AV940_00655	COG1960	acyl-CoA dehydrogenase activity
AV940_00660	COG0583	DNA-binding transcription factor activity
AV940_00675	COG3106	COG3106 Predicted ATPase
AV940_00695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AV940_00710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AV940_00725	COG4771	TonB-dependent receptor
AV940_00730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV940_00740	COG0778	Nitroreductase
AV940_00740	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AV940_00755	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AV940_00760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AV940_00765	COG1309	transcriptional regulator
AV940_00790	COG1953	Uracil, thiamine, allantoin
AV940_00800	COG3071	HemY protein
AV940_00805	COG2959	enzyme of heme biosynthesis
AV940_00815	COG0181	hydroxymethylbilane synthase activity
AV940_00820	COG0745	RESPONSE REGULATOR receiver
AV940_00820	COG3706	GGDEF domain
AV940_00830	COG0194	GDP metabolic process
AV940_00840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV940_00850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV940_00855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AV940_00865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV940_00865	COG0678	peroxiredoxin activity
AV940_00885	COG1178	ABC-type Fe3 transport system permease component
AV940_00890	COG3842	ATPase activity
AV940_00895	COG2081	HI0933 family
AV940_00900	COG0668	transmembrane transport
AV940_00925	COG3447	MASE1 domain protein
AV940_00925	COG5002	protein histidine kinase activity
AV940_00925	COG5001	Diguanylate cyclase
AV940_00935	COG0583	DNA-binding transcription factor activity
AV940_00945	COG2076	Multidrug Resistance protein
AV940_00960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV940_00965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV940_00975	COG0427	acetyl-CoA hydrolase
AV940_00980	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV940_00990	COG0840	transmembrane signaling receptor activity
AV940_01000	COG3064	Membrane
AV940_01005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AV940_01010	COG5002	protein histidine kinase activity
AV940_01010	COG5001	Diguanylate cyclase
AV940_01020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AV940_01030	COG0514	ATP-dependent DNA helicase (RecQ)
AV940_01035	COG2050	protein possibly involved in aromatic compounds catabolism
AV940_01040	COG2239	Acts as a magnesium transporter
AV940_01050	COG0745	RESPONSE REGULATOR receiver
AV940_01050	COG3706	GGDEF domain
AV940_01065	COG1011	Hydrolase
AV940_01080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AV940_01085	COG0019	diaminopimelate decarboxylase activity
AV940_01115	COG0163	prenyltransferase activity
AV940_01120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV940_01130	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AV940_01155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AV940_01160	COG2814	Major facilitator Superfamily
AV940_01165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV940_01185	COG1085	galactose-1-phosphate uridylyltransferase
AV940_01190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AV940_01200	COG0629	single-stranded DNA binding
AV940_01240	COG3710	Transcriptional regulator
AV940_01250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV940_01270	COG4615	Cyclic peptide transporter
AV940_01285	COG0745	RESPONSE REGULATOR receiver
AV940_01295	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV940_01325	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV940_01350	COG1349	DNA-binding transcription factor activity
AV940_01390	COG3409	Peptidoglycan-binding domain 1 protein
AV940_01390	COG3267	Type II secretory pathway component ExeA
AV940_01400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV940_01405	COG1459	type II secretion system
AV940_01445	COG1077	Cell shape determining protein MreB Mrl
AV940_01450	COG1792	Involved in formation and maintenance of cell shape
AV940_01455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AV940_01465	COG1530	ribonuclease E activity
AV940_01475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV940_01480	COG0312	modulator of DNA gyrase
AV940_01490	COG3028	Belongs to the UPF0307 family
AV940_01495	COG0312	modulator of DNA gyrase
AV940_01510	COG0745	RESPONSE REGULATOR receiver
AV940_01515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV940_01515	COG4191	Histidine kinase
AV940_01520	COG0297	glycogen (starch) synthase activity
AV940_01530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AV940_01540	COG1194	a g-specific adenine glycosylase
AV940_01595	COG0745	RESPONSE REGULATOR receiver
AV940_01600	COG0643	Histidine kinase
AV940_01600	COG2198	Histidine kinase
AV940_01605	COG0835	chemotaxis
AV940_01620	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AV940_01625	COG2201	protein-glutamate methylesterase activity
AV940_01640	COG0501	Belongs to the peptidase M48B family
AV940_01700	COG1609	Transcriptional regulator
AV940_01705	COG0673	inositol 2-dehydrogenase activity
AV940_01715	COG2211	Major facilitator Superfamily
AV940_01765	COG1454	alcohol dehydrogenase
AV940_01790	COG0051	transcription antitermination factor activity, RNA binding
AV940_01805	COG0089	rRNA binding
AV940_01815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AV940_01825	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AV940_01840	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AV940_01845	COG0438	transferase activity, transferring glycosyl groups
AV940_01850	COG0859	PFAM glycosyl transferase family 9
AV940_01855	COG1519	Transferase
AV940_01880	COG0339	signal peptide processing
AV940_01890	COG0788	formyltetrahydrofolate deformylase activity
AV940_01900	COG1643	Atp-dependent helicase
AV940_01905	COG2951	lytic endotransglycosylase activity
AV940_01915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AV940_01925	COG2354	Protein conserved in bacteria
AV940_01950	COG0004	ammonium transporteR
AV940_01955	COG0405	Gamma-glutamyltransferase
AV940_01960	COG2837	iron assimilation
AV940_01975	COG0540	Belongs to the ATCase OTCase family
AV940_02000	COG0784	Response regulator, receiver
AV940_02000	COG2205	protein histidine kinase activity
AV940_02000	COG5002	protein histidine kinase activity
AV940_02025	COG1012	belongs to the aldehyde dehydrogenase family
AV940_02035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AV940_02045	COG0512	Glutamine amidotransferase of anthranilate synthase
AV940_02050	COG0180	Tryptophanyl-tRNA synthetase
AV940_02055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AV940_02075	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AV940_02085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AV940_02120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AV940_02125	COG0281	malic enzyme
AV940_02135	COG0625	glutathione transferase activity
AV940_02170	COG5001	Diguanylate cyclase
AV940_02170	COG3300	MHYT domain
AV940_02175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AV940_02175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AV940_02185	COG0137	argininosuccinate synthase activity
AV940_02190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AV940_02205	COG1803	Methylglyoxal synthase
AV940_02215	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AV940_02230	COG0745	RESPONSE REGULATOR receiver
AV940_02235	COG2205	protein histidine kinase activity
AV940_02240	COG2267	carboxylic ester hydrolase activity
AV940_02245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AV940_02260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV940_02270	COG4942	peptidase
AV940_02280	COG2861	carbohydrate metabolic process
AV940_02290	COG0584	glycerophosphoryl diester phosphodiesterase
AV940_02305	COG1162	GTPase activity
AV940_02310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AV940_02325	COG0457	Tetratricopeptide repeat
AV940_02340	COG0028	Belongs to the TPP enzyme family
AV940_02360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AV940_02365	COG0805	protein transport
AV940_02380	COG3706	GGDEF domain
AV940_02390	COG0248	Ppx GppA phosphatase
AV940_02395	COG0513	Belongs to the DEAD box helicase family
AV940_02400	COG3118	belongs to the thioredoxin family
AV940_02405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AV940_02415	COG2205	protein histidine kinase activity
AV940_02415	COG0784	Response regulator, receiver
AV940_02420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AV940_02430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AV940_02450	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AV940_02455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AV940_02455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AV940_02460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AV940_02475	COG0783	Belongs to the Dps family
AV940_02480	COG2133	pyrroloquinoline quinone binding
AV940_02490	COG3118	belongs to the thioredoxin family
AV940_02500	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AV940_02510	COG1012	belongs to the aldehyde dehydrogenase family
AV940_02530	COG1757	Na H antiporter
AV940_02550	COG3876	Protein conserved in bacteria
AV940_02555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AV940_02575	COG0346	lactoylglutathione lyase activity
AV940_02590	COG0840	transmembrane signaling receptor activity
AV940_02650	COG4115	mRNA cleavage
AV940_02655	COG2161	toxin-antitoxin pair type II binding
AV940_02685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AV940_02690	COG0521	Mo-molybdopterin cofactor biosynthetic process
AV940_02695	COG0315	cyclic pyranopterin monophosphate synthase activity
AV940_02700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AV940_02705	COG0314	molybdopterin synthase activity
AV940_02720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AV940_02725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV940_02745	COG4771	TonB-dependent receptor
AV940_02755	COG1960	acyl-CoA dehydrogenase activity
AV940_02785	COG0596	Alpha beta hydrolase
AV940_02790	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV940_02790	COG1024	Enoyl-CoA hydratase
AV940_02795	COG0183	Belongs to the thiolase family
AV940_02800	COG1960	acyl-CoA dehydrogenase activity
AV940_02805	COG0596	Alpha beta hydrolase
AV940_02835	COG0183	Belongs to the thiolase family
AV940_02840	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV940_02840	COG1024	Enoyl-CoA hydratase
AV940_02850	COG0006	proline dipeptidase activity
AV940_02860	COG0142	geranyltranstransferase activity
AV940_02920	COG1238	metal cluster binding
AV940_02930	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AV940_02935	COG0585	pseudouridine synthase activity
AV940_02950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AV940_02960	COG0840	transmembrane signaling receptor activity
AV940_02965	COG0506	proline dehydrogenase activity
AV940_02965	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AV940_02965	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AV940_02980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV940_02990	COG2205	protein histidine kinase activity
AV940_02990	COG2770	Histidine kinase
AV940_02995	COG4991	sh3 domain protein
AV940_03000	COG3025	triphosphatase activity
AV940_03015	COG0494	nUDIX hydrolase
AV940_03020	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AV940_03025	COG0730	response to heat
AV940_03030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AV940_03035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AV940_03040	COG2201	protein-glutamate methylesterase activity
AV940_03045	COG3706	GGDEF domain
AV940_03050	COG0784	Response regulator, receiver
AV940_03050	COG5002	protein histidine kinase activity
AV940_03070	COG0564	pseudouridine synthase activity
AV940_03080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AV940_03090	COG1802	Transcriptional regulator
AV940_03095	COG3119	arylsulfatase activity
AV940_03100	COG1012	belongs to the aldehyde dehydrogenase family
AV940_03105	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_03110	COG1063	alcohol dehydrogenase
AV940_03115	COG4948	Mandelate Racemase Muconate Lactonizing
AV940_03120	COG2814	Major facilitator Superfamily
AV940_03140	COG2124	cytochrome p450
AV940_03240	COG3119	arylsulfatase activity
AV940_03275	COG3119	arylsulfatase activity
AV940_03290	COG1648	precorrin-2 dehydrogenase activity
AV940_03290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV940_03310	COG1538	Outer membrane efflux protein
AV940_03315	COG0494	nUDIX hydrolase
AV940_03330	COG3150	esterase
AV940_03345	COG4251	negative regulation of phosphorylation
AV940_03350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV940_03370	COG1509	lysine 2,3-aminomutase activity
AV940_03400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV940_03415	COG0271	Belongs to the BolA IbaG family
AV940_03420	COG0671	phosphoesterase, PA-phosphatase related
AV940_03430	COG3707	response regulator
AV940_03440	COG0659	secondary active sulfate transmembrane transporter activity
AV940_03445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AV940_03450	COG2146	nitrite reductase [NAD(P)H] activity
AV940_03455	COG0243	molybdopterin cofactor binding
AV940_03460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AV940_03460	COG1648	precorrin-2 dehydrogenase activity
AV940_03475	COG1116	anion transmembrane transporter activity
AV940_03475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AV940_03480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AV940_03485	COG1116	anion transmembrane transporter activity
AV940_03500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV940_03505	COG4206	TonB-dependent receptor
AV940_03510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AV940_03515	COG0348	domain, Protein
AV940_03530	COG1960	acyl-CoA dehydrogenase activity
AV940_03535	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_03555	COG4948	Mandelate Racemase Muconate Lactonizing
AV940_03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV940_03575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV940_03595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AV940_03600	COG0358	DNA primase activity
AV940_03605	COG1610	YqeY-like protein
AV940_03625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AV940_03630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV940_03645	COG0537	adenosine 5'-monophosphoramidase activity
AV940_03660	COG3135	benzoate transporter
AV940_03665	COG1396	sequence-specific DNA binding
AV940_03670	COG2974	May be involved in recombination
AV940_03675	COG4191	Histidine kinase
AV940_03675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV940_03680	COG0745	RESPONSE REGULATOR receiver
AV940_03685	COG5002	protein histidine kinase activity
AV940_03715	COG0811	peptide transport
AV940_03720	COG0811	peptide transport
AV940_03725	COG0848	biopolymer transport protein
AV940_03730	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AV940_03740	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AV940_03745	COG3437	response regulator, receiver
AV940_03755	COG0318	PFAM AMP-dependent synthetase and ligase
AV940_03765	COG2133	pyrroloquinoline quinone binding
AV940_03770	COG1049	propionate catabolic process, 2-methylcitrate cycle
AV940_03790	COG0527	aspartate kinase activity
AV940_03795	COG0840	transmembrane signaling receptor activity
AV940_03800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AV940_03810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AV940_03815	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AV940_03820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV940_03825	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AV940_03830	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AV940_03840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AV940_03860	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AV940_03870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AV940_03875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AV940_03880	COG3956	TIGRFAM MazG family protein
AV940_03900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AV940_03905	COG1595	DNA-templated transcription, initiation
AV940_03915	COG4206	TonB-dependent receptor
AV940_03925	COG1473	amidohydrolase
AV940_03930	COG0723	plastoquinol--plastocyanin reductase activity
AV940_03935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AV940_03940	COG2857	Cytochrome c1
AV940_03945	COG0625	glutathione transferase activity
AV940_03950	COG2969	positive regulation of protein catabolic process
AV940_03955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV940_03955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV940_03960	COG2207	Transcriptional regulator
AV940_03960	COG3708	Transcriptional regulator
AV940_03970	COG2239	Acts as a magnesium transporter
AV940_03975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV940_03985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AV940_03995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AV940_04000	COG1137	ATPase activity
AV940_04015	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AV940_04030	COG1127	ABC transporter
AV940_04035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AV940_04040	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV940_04045	COG2854	intermembrane phospholipid transfer
AV940_04055	COG5007	Belongs to the BolA IbaG family
AV940_04065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV940_04070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AV940_04080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AV940_04095	COG2207	Transcriptional regulator
AV940_04110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV940_04125	COG5001	Diguanylate cyclase
AV940_04125	COG3300	MHYT domain
AV940_04130	COG0784	Response regulator, receiver
AV940_04130	COG2205	protein histidine kinase activity
AV940_04135	COG0683	leucine binding
AV940_04140	COG2207	Transcriptional regulator
AV940_04145	COG1979	alcohol dehydrogenase
AV940_04170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AV940_04180	COG0126	phosphoglycerate kinase activity
AV940_04185	COG3588	fructose-bisphosphate aldolase
AV940_04190	COG1506	peptidase
AV940_04190	COG0823	Involved in the tonB-independent uptake of proteins
AV940_04190	COG4946	Tricorn protease homolog
AV940_04195	COG0248	Ppx GppA phosphatase
AV940_04200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AV940_04210	COG0573	inorganic phosphate transmembrane transporter activity
AV940_04215	COG0581	inorganic phosphate transmembrane transporter activity
AV940_04220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AV940_04230	COG0306	phosphate transporter
AV940_04240	COG0583	DNA-binding transcription factor activity
AV940_04265	COG1272	protein, Hemolysin III
AV940_04285	COG0477	Major facilitator Superfamily
AV940_04290	COG1609	Transcriptional regulator
AV940_04290	COG2207	Transcriptional regulator
AV940_04295	COG1070	Carbohydrate kinase
AV940_04300	COG2115	Belongs to the xylose isomerase family
AV940_04305	COG3291	Pkd domain containing protein
AV940_04305	COG5520	Belongs to the glycosyl hydrolase 30 family
AV940_04305	COG4447	cellulose binding
AV940_04310	COG2207	Transcriptional regulator
AV940_04325	COG1472	Belongs to the glycosyl hydrolase 3 family
AV940_04330	COG1846	Transcriptional regulator
AV940_04335	COG1764	response to oxidative stress
AV940_04350	COG1739	Uncharacterized protein family UPF0029
AV940_04360	COG0420	3'-5' exonuclease activity
AV940_04365	COG0419	ATPase involved in DNA repair
AV940_04370	COG3706	GGDEF domain
AV940_04380	COG2971	BadF BadG BcrA BcrD
AV940_04385	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AV940_04390	COG1752	Esterase of the alpha-beta hydrolase superfamily
AV940_04395	COG0488	(ABC) transporter
AV940_04430	COG4667	esterase of the alpha-beta hydrolase superfamily
AV940_04500	COG1346	cytolysis
AV940_04530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AV940_04540	COG0513	Belongs to the DEAD box helicase family
AV940_04550	COG3267	Type II secretory pathway component ExeA
AV940_04550	COG3409	Peptidoglycan-binding domain 1 protein
AV940_04560	COG3437	response regulator, receiver
AV940_04560	COG0784	Response regulator, receiver
AV940_04565	COG0066	3-isopropylmalate dehydratase activity
AV940_04575	COG0473	3-isopropylmalate dehydrogenase activity
AV940_04580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AV940_04610	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AV940_04625	COG4555	ABC transporter
AV940_04630	COG1668	transmembrane transport
AV940_04650	COG4133	protoheme IX ABC transporter activity
AV940_04655	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV940_04660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV940_04665	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AV940_04675	COG1138	Cytochrome C-type biogenesis protein
AV940_04680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV940_04695	COG2853	Lipoprotein
AV940_04700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AV940_04710	COG3104	oligopeptide transport
AV940_04725	COG1682	transport, permease protein
AV940_04755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AV940_04760	COG1555	photosystem II stabilization
AV940_04760	COG1596	polysaccharide export
AV940_04765	COG0473	3-isopropylmalate dehydrogenase activity
AV940_04780	COG1611	Belongs to the LOG family
AV940_04785	COG3706	GGDEF domain
AV940_04785	COG0745	RESPONSE REGULATOR receiver
AV940_04790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV940_04790	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AV940_04860	COG0564	pseudouridine synthase activity
AV940_04880	COG0024	Methionine aminopeptidase
AV940_04885	COG0052	Belongs to the universal ribosomal protein uS2 family
AV940_04895	COG0528	UMP kinase activity
AV940_04905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AV940_04910	COG0575	Belongs to the CDS family
AV940_04915	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AV940_04920	COG0750	zinc metalloprotease
AV940_04935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV940_04940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV940_04955	COG0587	DNA-directed DNA polymerase activity
AV940_04960	COG0825	malonyl-CoA metabolic process
AV940_04965	COG0037	tRNA processing
AV940_04985	COG0590	tRNA wobble adenosine to inosine editing
AV940_04995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AV940_04995	COG0047	phosphoribosylformylglycinamidine synthase activity
AV940_05000	COG2840	Smr protein MutS2
AV940_05035	COG3547	Transposase (IS116 IS110 IS902 family)
AV940_05040	COG0513	Belongs to the DEAD box helicase family
AV940_05045	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AV940_05050	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AV940_05055	COG0583	DNA-binding transcription factor activity
AV940_05075	COG1760	l-serine dehydratase
AV940_05080	COG0494	nUDIX hydrolase
AV940_05085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AV940_05095	COG1322	Protein conserved in bacteria
AV940_05100	COG1404	Belongs to the peptidase S8 family
AV940_05105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AV940_05110	COG0022	dehydrogenase e1 component
AV940_05115	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV940_05120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AV940_05125	COG0515	serine threonine protein kinase
AV940_05130	COG1946	Acyl-CoA thioesterase
AV940_05140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV940_05150	COG1956	GAF domain-containing protein
AV940_05165	COG0793	Belongs to the peptidase S41A family
AV940_05170	COG0733	neurotransmitter:sodium symporter activity
AV940_05180	COG0308	aminopeptidase N
AV940_05210	COG2902	Dehydrogenase
AV940_05215	COG0167	dihydroorotate dehydrogenase activity
AV940_05240	COG3130	regulation of translation
AV940_05245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AV940_05255	COG0415	Belongs to the DNA photolyase family
AV940_05260	COG0415	Belongs to the DNA photolyase family
AV940_05265	COG3046	protein related to deoxyribodipyrimidine photolyase
AV940_05290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AV940_05295	COG0589	response to stress
AV940_05305	COG0069	glutamate synthase activity
AV940_05320	COG2193	ferroxidase activity
AV940_05330	COG3278	Belongs to the heme-copper respiratory oxidase family
AV940_05345	COG2010	Cytochrome c
AV940_05355	COG2217	Heavy metal translocating P-type atpase
AV940_05370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV940_05380	COG0037	tRNA processing
AV940_05385	COG1752	Esterase of the alpha-beta hydrolase superfamily
AV940_05405	COG1280	lysine exporter protein (LysE YggA)
AV940_05410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AV940_05415	COG2897	thiosulfate sulfurtransferase activity
AV940_05420	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AV940_05470	COG0322	excinuclease ABC activity
AV940_05475	COG2197	response regulator
AV940_05480	COG1741	Belongs to the pirin family
AV940_05490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AV940_05510	COG0745	RESPONSE REGULATOR receiver
AV940_05515	COG0642	Histidine kinase
AV940_05530	COG0670	Belongs to the BI1 family
AV940_05540	COG2923	Belongs to the DsrF TusC family
AV940_05550	COG2920	part of a sulfur-relay system
AV940_05555	COG0561	phosphatase activity
AV940_05570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AV940_05575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AV940_05580	COG1674	ftsk spoiiie
AV940_05580	COG0531	amino acid
AV940_05590	COG0686	Belongs to the AlaDH PNT family
AV940_05595	COG0284	orotidine-5'-phosphate decarboxylase activity
AV940_05600	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AV940_05605	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AV940_05615	COG0776	regulation of translation
AV940_05620	COG0539	negative regulation of cytoplasmic translation
AV940_05625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AV940_05630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AV940_05635	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AV940_05650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV940_05655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AV940_05660	COG0633	Ferredoxin
AV940_05665	COG5002	protein histidine kinase activity
AV940_05695	COG0789	Transcriptional regulator
AV940_05790	COG1131	(ABC) transporter
AV940_05825	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AV940_05830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AV940_05840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AV940_05850	COG4783	chaperone-mediated protein folding
AV940_05860	COG1393	Belongs to the ArsC family
AV940_05895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AV940_05930	COG0572	uridine kinase
AV940_05935	COG3769	mannosylglycerate metabolic process
AV940_05940	COG1215	transferase activity, transferring glycosyl groups
AV940_05950	COG0303	'Molybdopterin
AV940_05955	COG0534	Mate efflux family protein
AV940_05975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AV940_05985	COG0405	Gamma-glutamyltransferase
AV940_05990	COG1024	Enoyl-CoA hydratase
AV940_06025	COG1448	Aminotransferase
AV940_06030	COG1671	Belongs to the UPF0178 family
AV940_06035	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_06045	COG1960	acyl-CoA dehydrogenase activity
AV940_06050	COG1917	Cupin 2, conserved barrel domain protein
AV940_06050	COG2207	Transcriptional regulator
AV940_06100	COG0596	Alpha beta hydrolase
AV940_06110	COG0716	FMN binding
AV940_06130	COG3265	gluconokinase activity
AV940_06135	COG1609	Transcriptional regulator
AV940_06145	COG1984	allophanate hydrolase subunit 2
AV940_06155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AV940_06160	COG2996	Protein conserved in bacteria
AV940_06165	COG1765	OsmC-like protein
AV940_06170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV940_06195	COG0436	Aminotransferase
AV940_06200	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV940_06205	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AV940_06215	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AV940_06225	COG1238	metal cluster binding
AV940_06270	COG4628	conserved protein (DUF2132)
AV940_06280	COG0454	-acetyltransferase
AV940_06285	COG1119	ATPase activity
AV940_06295	COG1185	polyribonucleotide nucleotidyltransferase activity
AV940_06320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV940_06360	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV940_06365	COG0149	triose-phosphate isomerase activity
AV940_06370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AV940_06375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AV940_06380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV940_06385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AV940_06390	COG1534	Rna-binding protein
AV940_06400	COG1067	ATP-dependent peptidase activity
AV940_06405	COG0495	leucyl-tRNA aminoacylation
AV940_06415	COG1466	dna polymerase III delta subunit
AV940_06420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AV940_06425	COG0799	negative regulation of ribosome biogenesis
AV940_06430	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AV940_06435	COG0768	penicillin binding
AV940_06440	COG0772	Belongs to the SEDS family
AV940_06445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV940_06450	COG1686	Belongs to the peptidase S11 family
AV940_06455	COG2921	Belongs to the UPF0250 family
AV940_06460	COG0321	lipoyl(octanoyl) transferase activity
AV940_06465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AV940_06475	COG0252	asparaginase activity
AV940_06485	COG0778	Nitroreductase
AV940_06500	COG0616	signal peptide processing
AV940_06520	COG0492	ferredoxin-NADP+ reductase activity
AV940_06525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AV940_06530	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AV940_06535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AV940_06540	COG0542	response to heat
AV940_06545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AV940_06550	COG1278	Cold shock
AV940_06560	COG1187	pseudouridine synthase activity
AV940_06565	COG0482	sulfurtransferase activity
AV940_06570	COG2915	High frequency lysogenization protein hflD homolog
AV940_06575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AV940_06585	COG2850	peptidyl-arginine hydroxylation
AV940_06600	COG0277	FAD linked oxidase domain protein
AV940_06600	COG0247	lactate metabolic process
AV940_06605	COG3123	guanosine phosphorylase activity
AV940_06610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AV940_06655	COG1695	Transcriptional regulator
AV940_06670	COG1077	Cell shape determining protein MreB Mrl
AV940_06695	COG3265	gluconokinase activity
AV940_06705	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_06720	COG1609	Transcriptional regulator
AV940_06725	COG0679	Auxin Efflux Carrier
AV940_06745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AV940_06745	COG0574	Belongs to the PEP-utilizing enzyme family
AV940_06765	COG1942	4-Oxalocrotonate Tautomerase
AV940_06785	COG1714	RDD family
AV940_06805	COG3706	GGDEF domain
AV940_06805	COG0745	RESPONSE REGULATOR receiver
AV940_06810	COG0702	epimerase
AV940_06820	COG0084	hydrolase, TatD family'
AV940_06825	COG0470	DNA polymerase III
AV940_06835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AV940_06840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AV940_06845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AV940_06850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AV940_06865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AV940_06870	COG0416	fatty acid biosynthetic process
AV940_06880	COG1399	metal-binding, possibly nucleic acid-binding protein
AV940_06885	COG0424	maF-like protein
AV940_06890	COG0546	phosphoglycolate phosphatase activity
AV940_06900	COG1530	ribonuclease E activity
AV940_06920	COG2153	protein acetylation
AV940_06940	COG0625	glutathione transferase activity
AV940_06955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV940_06965	COG0583	DNA-binding transcription factor activity
AV940_06975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AV940_06980	COG3724	N-succinylarginine dihydrolase activity
AV940_06990	COG1301	dicarboxylic acid transport
AV940_06995	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV940_07000	COG1136	(ABC) transporter
AV940_07005	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV940_07020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV940_07025	COG0328	RNA-DNA hybrid ribonuclease activity
AV940_07050	COG1643	Atp-dependent helicase
AV940_07090	COG2205	protein histidine kinase activity
AV940_07090	COG3437	response regulator, receiver
AV940_07090	COG3850	Histidine kinase
AV940_07090	COG4999	Histidine kinase
AV940_07095	COG2925	Exonuclease
AV940_07110	COG0183	Belongs to the thiolase family
AV940_07115	COG0789	Transcriptional regulator
AV940_07120	COG1960	acyl-CoA dehydrogenase activity
AV940_07125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AV940_07130	COG1024	Enoyl-CoA hydratase
AV940_07165	COG1957	nucleoside hydrolase
AV940_07180	COG2814	Major facilitator Superfamily
AV940_07215	COG0708	Exodeoxyribonuclease III
AV940_07230	COG4591	ABC-type transport system involved in lipoprotein release permease component
AV940_07240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AV940_07250	COG2096	Adenosyltransferase
AV940_07260	COG1472	Belongs to the glycosyl hydrolase 3 family
AV940_07270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AV940_07285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV940_07285	COG0072	phenylalanine-tRNA ligase activity
AV940_07315	COG2244	polysaccharide biosynthetic process
AV940_07325	COG0463	Glycosyl transferase, family 2
AV940_07330	COG0463	Glycosyl transferase, family 2
AV940_07330	COG1216	Glycosyl transferase, family 2
AV940_07345	COG1045	serine acetyltransferase
AV940_07355	COG0438	transferase activity, transferring glycosyl groups
AV940_07390	COG4464	protein tyrosine phosphatase activity
AV940_07395	COG0489	protein tyrosine kinase activity
AV940_07400	COG1596	polysaccharide export
AV940_07410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AV940_07430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AV940_07445	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_07475	COG0154	amidase activity
AV940_07485	COG0730	response to heat
AV940_07490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AV940_07505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV940_07510	COG2233	PERMEase
AV940_07525	COG5002	protein histidine kinase activity
AV940_07525	COG0784	Response regulator, receiver
AV940_07530	COG3706	GGDEF domain
AV940_07530	COG0745	RESPONSE REGULATOR receiver
AV940_07535	COG5001	Diguanylate cyclase
AV940_07535	COG3300	MHYT domain
AV940_07545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AV940_07550	COG2252	PERMEase
AV940_07565	COG1309	transcriptional regulator
AV940_07575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV940_07590	COG2351	hydroxyisourate hydrolase activity
AV940_07595	COG0402	S-adenosylhomocysteine deaminase activity
AV940_07605	COG3447	MASE1 domain protein
AV940_07605	COG5002	protein histidine kinase activity
AV940_07605	COG5001	Diguanylate cyclase
AV940_07625	COG3706	GGDEF domain
AV940_07640	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AV940_07665	COG2190	(PTS) system
AV940_07665	COG2211	Major facilitator Superfamily
AV940_07670	COG1393	Belongs to the ArsC family
AV940_07700	COG2988	succinylglutamate desuccinylase activity
AV940_07710	COG0058	SHG alpha-glucan phosphorylase activity
AV940_07715	COG0033	Phosphoglucomutase
AV940_07720	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AV940_07725	COG0714	Associated with various cellular activities
AV940_07740	COG2116	formate transmembrane transporter activity
AV940_07745	COG2815	serine threonine protein kinase
AV940_07745	COG0515	serine threonine protein kinase
AV940_07750	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AV940_07775	COG0583	DNA-binding transcription factor activity
AV940_07790	COG3094	Invasion gene expression up-regulator, SirB
AV940_07795	COG3437	response regulator, receiver
AV940_07795	COG0784	Response regulator, receiver
AV940_07800	COG2890	protein-(glutamine-N5) methyltransferase activity
AV940_07810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AV940_07815	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AV940_07820	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AV940_07830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AV940_07835	COG3300	MHYT domain
AV940_07835	COG5001	Diguanylate cyclase
AV940_07845	COG1064	alcohol dehydrogenase
AV940_07860	COG0012	GTP binding
AV940_07865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV940_07880	COG1115	amino acid carrier protein
AV940_07885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AV940_07900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV940_07910	COG1702	phosphate starvation-inducible protein PhoH
AV940_07920	COG4535	Mg2 and Co2 transporter CorC
AV940_07925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AV940_07930	COG0857	belongs to the CobB CobQ family
AV940_07930	COG0280	phosphate acetyltransferase
AV940_07935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AV940_07940	COG0071	Belongs to the small heat shock protein (HSP20) family
AV940_07965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV940_07970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AV940_07975	COG0505	Belongs to the CarA family
AV940_07980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AV940_07995	COG5001	Diguanylate cyclase
AV940_07995	COG2203	Gaf domain
AV940_07995	COG3706	GGDEF domain
AV940_07995	COG4251	negative regulation of phosphorylation
AV940_08000	COG3909	cytochrome
AV940_08005	COG0484	heat shock protein binding
AV940_08015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AV940_08020	COG2205	protein histidine kinase activity
AV940_08020	COG0784	Response regulator, receiver
AV940_08030	COG4771	TonB-dependent receptor
AV940_08035	COG2610	gluconate transmembrane transporter activity
AV940_08040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV940_08050	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_08060	COG0497	DNA recombination
AV940_08065	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV940_08070	COG0500	methyltransferase
AV940_08075	COG2733	membrane
AV940_08090	COG0110	maltose O-acetyltransferase activity
AV940_08095	COG0656	L-ascorbic acid biosynthetic process
AV940_08110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AV940_08115	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AV940_08120	COG0009	L-threonylcarbamoyladenylate synthase
AV940_08125	COG0613	PHP domain protein
AV940_08130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AV940_08140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AV940_08145	COG0135	phosphoribosylanthranilate isomerase activity
AV940_08145	COG0134	indole-3-glycerol-phosphate synthase activity
AV940_08155	COG0159	tryptophan synthase activity
AV940_08160	COG2350	Protein conserved in bacteria
AV940_08175	COG0745	RESPONSE REGULATOR receiver
AV940_08180	COG2205	protein histidine kinase activity
AV940_08185	COG0628	permease
AV940_08190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AV940_08195	COG1090	epimerase
AV940_08200	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AV940_08205	COG4181	ATPase activity
AV940_08225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV940_08245	COG0745	RESPONSE REGULATOR receiver
AV940_08255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AV940_08260	COG5265	(ABC) transporter
AV940_08275	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AV940_08285	COG4139	cobalamin transport
AV940_08290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AV940_08305	COG2226	methyltransferase
AV940_08305	COG1073	alpha beta
AV940_08310	COG0156	8-amino-7-oxononanoate synthase activity
AV940_08335	COG0456	acetyltransferase
AV940_08340	COG0189	ligase activity
AV940_08355	COG0017	Asparaginyl-tRNA synthetase
AV940_08365	COG2995	paraquat-inducible protein a
AV940_08370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AV940_08370	COG3008	intermembrane lipid transfer
AV940_08380	COG3706	GGDEF domain
AV940_08400	COG0583	DNA-binding transcription factor activity
AV940_08405	COG1309	transcriptional regulator
AV940_08415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AV940_08420	COG0517	IMP dehydrogenase activity
AV940_08435	COG0583	DNA-binding transcription factor activity
AV940_08440	COG3038	cytochrome b561
AV940_08450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV940_08480	COG2271	Major facilitator Superfamily
AV940_08485	COG0784	Response regulator, receiver
AV940_08485	COG2205	protein histidine kinase activity
AV940_08525	COG0024	Methionine aminopeptidase
AV940_08535	COG0745	RESPONSE REGULATOR receiver
AV940_08535	COG3706	GGDEF domain
AV940_08560	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AV940_08570	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AV940_08575	COG2885	chlorophyll binding
AV940_08580	COG0823	Involved in the tonB-independent uptake of proteins
AV940_08595	COG0811	peptide transport
AV940_08600	COG0824	Thioesterase
AV940_08605	COG2255	four-way junction helicase activity
AV940_08620	COG0494	nUDIX hydrolase
AV940_08625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AV940_08640	COG2204	response regulator
AV940_08650	COG2205	protein histidine kinase activity
AV940_08670	COG3706	GGDEF domain
AV940_08670	COG0745	RESPONSE REGULATOR receiver
AV940_08680	COG0023	Translation Initiation Factor
AV940_08685	COG0745	RESPONSE REGULATOR receiver
AV940_08690	COG1605	Chorismate mutase
AV940_08690	COG0077	Prephenate dehydratase
AV940_08695	COG0840	transmembrane signaling receptor activity
AV940_08700	COG0287	Prephenate dehydrogenase
AV940_08700	COG1605	Chorismate mutase
AV940_08705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AV940_08710	COG2860	membrane
AV940_08725	COG0335	large ribosomal subunit rRNA binding
AV940_08730	COG0336	Belongs to the RNA methyltransferase TrmD family
AV940_08735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AV940_08740	COG0228	four-way junction DNA binding
AV940_08760	COG1132	(ABC) transporter
AV940_08765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV940_08775	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AV940_08805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AV940_08810	COG4137	Cytochrome C assembly protein
AV940_08815	COG4536	flavin adenine dinucleotide binding
AV940_08825	COG2062	phosphohistidine phosphatase, SixA
AV940_08830	COG1025	Belongs to the peptidase M16 family
AV940_08845	COG1250	3-hydroxyacyl-CoA dehydrogenase
AV940_08845	COG1024	Enoyl-CoA hydratase
AV940_08855	COG0714	Associated with various cellular activities
AV940_08875	COG2304	oxidoreductase activity
AV940_08900	COG3706	GGDEF domain
AV940_08905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV940_08910	COG0175	sulfate reduction
AV940_08915	COG0529	Catalyzes the synthesis of activated sulfate
AV940_08930	COG0471	metal ion transport
AV940_08930	COG3273	potassium ion transport
AV940_08955	COG0367	asparagine synthase
AV940_08965	COG0602	queuosine metabolic process
AV940_08990	COG0556	nucleotide-excision repair
AV940_08995	COG0534	Mate efflux family protein
AV940_09005	COG4657	Part of a membrane complex involved in electron transport
AV940_09010	COG2878	Part of a membrane complex involved in electron transport
AV940_09015	COG4656	Part of a membrane complex involved in electron transport
AV940_09020	COG4658	electron transport chain
AV940_09030	COG4660	Part of a membrane complex involved in electron transport
AV940_09035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AV940_09060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AV940_09065	COG1506	peptidase
AV940_09065	COG4946	Tricorn protease homolog
AV940_09065	COG0823	Involved in the tonB-independent uptake of proteins
AV940_09090	COG1278	Cold shock
AV940_09095	COG0346	lactoylglutathione lyase activity
AV940_09100	COG0584	glycerophosphoryl diester phosphodiesterase
AV940_09105	COG2885	chlorophyll binding
AV940_09110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AV940_09115	COG0450	alkyl hydroperoxide reductase
AV940_09140	COG4771	TonB-dependent receptor
AV940_09145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AV940_09155	COG2766	serine protein kinase
AV940_09160	COG2718	Belongs to the UPF0229 family
AV940_09165	COG2719	SpoVR family
AV940_09185	COG2890	protein-(glutamine-N5) methyltransferase activity
AV940_09190	COG2840	Smr protein MutS2
AV940_09215	COG1136	(ABC) transporter
AV940_09240	COG0612	Peptidase, M16
AV940_09250	COG0564	pseudouridine synthase activity
AV940_09255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AV940_09260	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AV940_09285	COG2175	clavaminate synthase activity
AV940_09315	COG0583	DNA-binding transcription factor activity
AV940_09330	COG0456	acetyltransferase
AV940_09385	COG0848	biopolymer transport protein
AV940_09390	COG0811	peptide transport
AV940_09395	COG0811	peptide transport
AV940_09435	COG0457	Tetratricopeptide repeat
AV940_09460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AV940_09465	COG1522	sequence-specific DNA binding
AV940_09470	COG0625	glutathione transferase activity
AV940_09500	COG1842	Phage shock protein A
AV940_09505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AV940_09510	COG0747	negative chemotaxis
AV940_09515	COG4168	peptide transport system, permease
AV940_09520	COG4171	peptide transport system, permease
AV940_09525	COG4172	Belongs to the ABC transporter superfamily
AV940_09530	COG4172	Belongs to the ABC transporter superfamily
AV940_09535	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AV940_09550	COG1607	acyl-coa hydrolase
AV940_09585	COG3590	peptidase
AV940_09590	COG1309	transcriptional regulator
AV940_09600	COG0659	secondary active sulfate transmembrane transporter activity
AV940_09605	COG0288	reversible hydration of carbon dioxide
AV940_09610	COG0583	DNA-binding transcription factor activity
AV940_09615	COG0583	DNA-binding transcription factor activity
AV940_09625	COG1410	methionine synthase
AV940_09625	COG0646	methionine synthase
AV940_09630	COG1410	methionine synthase
AV940_09630	COG0646	methionine synthase
AV940_09645	COG0835	chemotaxis
AV940_09655	COG1192	Involved in chromosome partitioning
AV940_09660	COG2201	protein-glutamate methylesterase activity
AV940_09665	COG2198	Histidine kinase
AV940_09665	COG0643	Histidine kinase
AV940_09670	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AV940_09685	COG0455	bacterial-type flagellum organization
AV940_09695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AV940_09710	COG1987	bacterial-type flagellum assembly
AV940_09760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AV940_09765	COG1766	The M ring may be actively involved in energy transduction
AV940_09775	COG2204	response regulator
AV940_09780	COG3852	Histidine kinase
AV940_09785	COG2204	response regulator
AV940_09795	COG1086	Polysaccharide biosynthesis protein
AV940_09800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AV940_09805	COG1083	cytidylyl-transferase
AV940_09815	COG2089	acid synthase
AV940_09830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV940_09870	COG2089	acid synthase
AV940_09875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AV940_09880	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AV940_09920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV940_09925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AV940_09945	COG1256	bacterial-type flagellum assembly
AV940_09950	COG3951	Flagellar rod assembly protein muramidase FlgJ
AV940_09950	COG1705	Flagellar rod assembly protein muramidase FlgJ
AV940_09965	COG4786	Flagellar basal body rod
AV940_09970	COG4787	bacterial-type flagellum-dependent cell motility
AV940_09975	COG1749	Flagellar hook protein flgE
AV940_09980	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AV940_09985	COG1558	bacterial-type flagellum-dependent cell motility
AV940_09990	COG1815	bacterial-type flagellum-dependent cell motility
AV940_09995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AV940_10000	COG0784	Response regulator, receiver
AV940_10000	COG0835	chemotaxis
AV940_10040	COG2197	response regulator
AV940_10045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AV940_10055	COG2885	chlorophyll binding
AV940_10160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV940_10160	COG2205	protein histidine kinase activity
AV940_10170	COG0205	6-phosphofructokinase activity
AV940_10175	COG3279	Response regulator of the LytR AlgR family
AV940_10180	COG3275	phosphorelay sensor kinase activity
AV940_10210	COG3081	Nucleoid-associated protein
AV940_10215	COG3082	Protein of unknown function (DUF1414)
AV940_10220	COG3083	sulfuric ester hydrolase activity
AV940_10230	COG2226	methyltransferase
AV940_10235	COG1024	Enoyl-CoA hydratase
AV940_10240	COG1960	acyl-CoA dehydrogenase activity
AV940_10250	COG2084	Dehydrogenase
AV940_10255	COG0386	Belongs to the glutathione peroxidase family
AV940_10260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV940_10265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV940_10270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AV940_10295	COG0616	signal peptide processing
AV940_10305	COG2267	carboxylic ester hydrolase activity
AV940_10310	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_10320	COG1609	Transcriptional regulator
AV940_10335	COG0366	Alpha amylase catalytic
AV940_10355	COG4667	esterase of the alpha-beta hydrolase superfamily
AV940_10390	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV940_10395	COG0567	Dehydrogenase, E1 component
AV940_10405	COG1053	succinate dehydrogenase
AV940_10410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AV940_10415	COG2009	succinate dehydrogenase
AV940_10435	COG0435	Glutathione S-transferase
AV940_10440	COG0579	oxidoreductase
AV940_10445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AV940_10485	COG1663	tetraacyldisaccharide 4'-kinase activity
AV940_10490	COG1132	(ABC) transporter
AV940_10505	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AV940_10515	COG1196	nuclear chromosome segregation
AV940_10535	COG0295	cytidine deaminase activity
AV940_10560	COG0477	Major facilitator Superfamily
AV940_10580	COG2318	DinB family
AV940_10585	COG0457	Tetratricopeptide repeat
AV940_10595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AV940_10605	COG2914	Belongs to the UPF0125 (RnfH) family
AV940_10610	COG2867	negative regulation of translational initiation
AV940_10650	COG0582	viral genome integration into host DNA
AV940_10675	COG4771	TonB-dependent receptor
AV940_10680	COG2814	Major facilitator Superfamily
AV940_10710	COG1012	belongs to the aldehyde dehydrogenase family
AV940_10720	COG1595	DNA-templated transcription, initiation
AV940_10750	COG0583	DNA-binding transcription factor activity
AV940_10770	COG5001	Diguanylate cyclase
AV940_10770	COG3300	MHYT domain
AV940_10785	COG2203	Gaf domain
AV940_10785	COG3706	GGDEF domain
AV940_10785	COG4251	negative regulation of phosphorylation
AV940_10785	COG5001	Diguanylate cyclase
AV940_10800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AV940_10805	COG4136	ATPase activity
AV940_10810	COG4135	transport system, permease component
AV940_10815	COG4134	Bacterial extracellular solute-binding protein
AV940_10830	COG4771	TonB-dependent receptor
AV940_10845	COG1032	radical SAM domain protein
AV940_10870	COG4774	siderophore transport
AV940_10880	COG0450	alkyl hydroperoxide reductase
AV940_10905	COG3153	acetyltransferase
AV940_10905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV940_10915	COG0596	Alpha beta hydrolase
AV940_10920	COG3706	GGDEF domain
AV940_10930	COG4269	membrane
AV940_10940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AV940_10955	COG0195	Participates in both transcription termination and antitermination
AV940_10965	COG3437	response regulator, receiver
AV940_10970	COG0784	Response regulator, receiver
AV940_10970	COG2198	Histidine kinase
AV940_10970	COG2205	protein histidine kinase activity
AV940_10985	COG4771	TonB-dependent receptor
AV940_10990	COG0668	transmembrane transport
AV940_11010	COG0668	transmembrane transport
AV940_11030	COG0246	Mannitol dehydrogenase
AV940_11040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV940_11045	COG2390	Transcriptional regulator
AV940_11155	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_11195	COG3268	Saccharopine dehydrogenase
AV940_11210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV940_11225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AV940_11230	COG1074	ATP-dependent DNA helicase activity
AV940_11235	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AV940_11245	COG1022	Amp-dependent synthetase and ligase
AV940_11250	COG5001	Diguanylate cyclase
AV940_11250	COG3300	MHYT domain
AV940_11275	COG0583	DNA-binding transcription factor activity
AV940_11295	COG0640	Transcriptional regulator
AV940_11305	COG0583	DNA-binding transcription factor activity
AV940_11315	COG2204	response regulator
AV940_11325	COG4251	negative regulation of phosphorylation
AV940_11330	COG0784	Response regulator, receiver
AV940_11360	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AV940_11385	COG3139	Protein of unknown function (DUF1315)
AV940_11395	COG1115	amino acid carrier protein
AV940_11400	COG2866	Carboxypeptidase
AV940_11420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AV940_11430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AV940_11435	COG1640	4-alpha-glucanotransferase
AV940_11445	COG0676	glucose-6-phosphate 1-epimerase activity
AV940_11450	COG0800	Aldolase
AV940_11460	COG0129	dihydroxy-acid dehydratase activity
AV940_11470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AV940_11475	COG1737	Transcriptional regulator
AV940_11480	COG0469	pyruvate kinase activity
AV940_11485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV940_11530	COG2205	protein histidine kinase activity
AV940_11535	COG0745	RESPONSE REGULATOR receiver
AV940_11560	COG3665	Urea carboxylase-associated protein
AV940_11570	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_11575	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AV940_11600	COG2721	sulfolactate sulfo-lyase activity
AV940_11605	COG1904	glucuronate isomerase
AV940_11610	COG0246	Mannitol dehydrogenase
AV940_11615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV940_11620	COG2755	lipolytic protein G-D-S-L family
AV940_11630	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AV940_11640	COG4677	pectinesterase activity
AV940_11645	COG3850	Histidine kinase
AV940_11645	COG2205	protein histidine kinase activity
AV940_11645	COG3437	response regulator, receiver
AV940_11645	COG4999	Histidine kinase
AV940_11660	COG2356	endonuclease I
AV940_11670	COG1024	Enoyl-CoA hydratase
AV940_11690	COG1609	Transcriptional regulator
AV940_11695	COG4948	Mandelate Racemase Muconate Lactonizing
AV940_11700	COG0673	inositol 2-dehydrogenase activity
AV940_11730	COG0746	molybdenum cofactor guanylyltransferase activity
AV940_11740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV940_11745	COG1764	response to oxidative stress
AV940_11760	COG3706	GGDEF domain
AV940_11770	COG0745	RESPONSE REGULATOR receiver
AV940_11775	COG3850	Histidine kinase
AV940_11775	COG5002	protein histidine kinase activity
AV940_11805	COG1957	nucleoside hydrolase
AV940_11810	COG0738	Major facilitator superfamily
AV940_11835	COG0840	transmembrane signaling receptor activity
AV940_11845	COG0753	catalase activity
AV940_11855	COG0330	HflC and HflK could
AV940_11875	COG0778	Nitroreductase
AV940_11895	COG0471	metal ion transport
AV940_11905	COG0489	protein tyrosine kinase activity
AV940_11910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV940_11910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV940_11915	COG2226	methyltransferase
AV940_11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV940_11925	COG1388	LysM domain
AV940_11925	COG0741	lytic transglycosylase activity
AV940_11945	COG2942	2-epimerase
AV940_11950	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AV940_11960	COG1609	Transcriptional regulator
AV940_11965	COG2942	2-epimerase
AV940_11970	COG3119	arylsulfatase activity
AV940_11985	COG4124	Belongs to the glycosyl hydrolase 26 family
AV940_12015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AV940_12025	COG1785	Belongs to the alkaline phosphatase family
AV940_12030	COG1785	Belongs to the alkaline phosphatase family
AV940_12045	COG2268	Band 7 protein
AV940_12065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AV940_12070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AV940_12075	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AV940_12080	COG2080	2 iron, 2 sulfur cluster binding
AV940_12090	COG0604	alcohol dehydrogenase
AV940_12100	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AV940_12125	COG0084	hydrolase, TatD family'
AV940_12145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AV940_12150	COG1286	toxin biosynthetic process
AV940_12155	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AV940_12160	COG0285	dihydrofolate synthase activity
AV940_12170	COG0101	tRNA pseudouridine synthase activity
AV940_12185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV940_12205	COG3706	GGDEF domain
AV940_12210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AV940_12210	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AV940_12240	COG3101	peptidyl-lysine hydroxylation
AV940_12285	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV940_12285	COG1902	pentaerythritol trinitrate reductase activity
AV940_12310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AV940_12315	COG1309	transcriptional regulator
AV940_12320	COG4399	Belongs to the UPF0754 family
AV940_12355	COG2186	Transcriptional regulator
AV940_12365	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AV940_12370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AV940_12375	COG2983	Belongs to the UPF0260 family
AV940_12380	COG0179	Fumarylacetoacetate (FAA) hydrolase
AV940_12395	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AV940_12400	COG0318	PFAM AMP-dependent synthetase and ligase
AV940_12405	COG2267	carboxylic ester hydrolase activity
AV940_12420	COG1214	PFAM Peptidase M22, glycoprotease
AV940_12425	COG1199	ATP-dependent helicase activity
AV940_12485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AV940_12490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AV940_12495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AV940_12500	COG0131	Imidazoleglycerol-phosphate dehydratase
AV940_12500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AV940_12505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AV940_12520	COG0140	phosphoribosyl-ATP diphosphatase activity
AV940_12520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AV940_12530	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_12540	COG1022	Amp-dependent synthetase and ligase
AV940_12560	COG0463	Glycosyl transferase, family 2
AV940_12580	COG0642	Histidine kinase
AV940_12585	COG0745	RESPONSE REGULATOR receiver
AV940_12590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV940_12595	COG0681	Belongs to the peptidase S26 family
AV940_12615	COG0326	Molecular chaperone. Has ATPase activity
AV940_12620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AV940_12645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AV940_12650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AV940_12660	COG3220	belongs to the UPF0276 family
AV940_12670	COG4249	Peptidase C14 caspase catalytic subunit p20
AV940_12670	COG2319	Wd-40 repeat
AV940_12685	COG5001	Diguanylate cyclase
AV940_12685	COG4251	negative regulation of phosphorylation
AV940_12685	COG3706	GGDEF domain
AV940_12685	COG2203	Gaf domain
AV940_12720	COG1183	phosphatidylcholine synthase activity
AV940_12740	COG0542	response to heat
AV940_12750	COG0564	pseudouridine synthase activity
AV940_12765	COG1595	DNA-templated transcription, initiation
AV940_12780	COG4221	oxidoreductase activity
AV940_12795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AV940_12805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AV940_12810	COG1722	exodeoxyribonuclease VII activity
AV940_12815	COG0142	geranyltranstransferase activity
AV940_12825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AV940_12830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AV940_12840	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AV940_12855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV940_12855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AV940_12870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AV940_12875	COG0488	(ABC) transporter
AV940_12885	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AV940_12895	COG0560	Phosphoserine phosphatase
AV940_12905	COG0084	hydrolase, TatD family'
AV940_12925	COG0681	Belongs to the peptidase S26 family
AV940_12950	COG1595	DNA-templated transcription, initiation
AV940_12955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AV940_12970	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AV940_12990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AV940_13050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AV940_13055	COG1047	Peptidyl-prolyl cis-trans
AV940_13065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AV940_13070	COG0196	riboflavin kinase activity
AV940_13075	COG0728	peptidoglycan biosynthetic process
AV940_13080	COG0268	Binds directly to 16S ribosomal RNA
AV940_13095	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_13100	COG0385	Bile acid
AV940_13125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV940_13130	COG0776	regulation of translation
AV940_13135	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AV940_13140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AV940_13145	COG0740	serine-type endopeptidase activity
AV940_13150	COG0544	peptidyl-prolyl cis-trans isomerase activity
AV940_13170	COG1720	tRNA m6t6A37 methyltransferase activity
AV940_13185	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AV940_13190	COG0123	including yeast histone deacetylase and acetoin utilization protein
AV940_13210	COG0517	IMP dehydrogenase activity
AV940_13210	COG0516	GMP reductase activity
AV940_13215	COG1570	exodeoxyribonuclease VII activity
AV940_13230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AV940_13235	COG2976	Protein conserved in bacteria
AV940_13260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AV940_13270	COG2166	iron-sulfur cluster assembly
AV940_13285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AV940_13290	COG0719	Fe-S assembly protein
AV940_13295	COG0396	ATPase activity
AV940_13300	COG0719	Fe-S assembly protein
AV940_13305	COG1104	cysteine desulfurase activity
AV940_13320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AV940_13325	COG0483	inositol monophosphate 1-phosphatase activity
AV940_13355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV940_13360	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AV940_13365	COG1862	Preprotein translocase
AV940_13370	COG0343	queuine tRNA-ribosyltransferase activity
AV940_13385	COG3789	protein conserved in bacteria
AV940_13390	COG1842	Phage shock protein A
AV940_13415	COG0754	glutathionylspermidine amidase activity
AV940_13430	COG2066	Belongs to the glutaminase family
AV940_13435	COG1785	Belongs to the alkaline phosphatase family
AV940_13490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AV940_13495	COG1045	serine acetyltransferase
AV940_13520	COG0438	transferase activity, transferring glycosyl groups
AV940_13565	COG0463	Glycosyl transferase, family 2
AV940_13565	COG1216	Glycosyl transferase, family 2
AV940_13600	COG0489	protein tyrosine kinase activity
AV940_13610	COG3267	Type II secretory pathway component ExeA
AV940_13610	COG3409	Peptidoglycan-binding domain 1 protein
AV940_13615	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AV940_13615	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AV940_13620	COG2827	Endonuclease containing a URI domain
AV940_13640	COG1560	Kdo2-lipid A biosynthetic process
AV940_13670	COG1960	acyl-CoA dehydrogenase activity
AV940_13685	COG1435	thymidine kinase activity
AV940_13695	COG1609	Transcriptional regulator
AV940_13700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AV940_13740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AV940_13745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AV940_13750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AV940_13755	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AV940_13780	COG2815	serine threonine protein kinase
AV940_13780	COG0515	serine threonine protein kinase
AV940_13815	COG4774	siderophore transport
AV940_13830	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_13845	COG1629	transport
AV940_13845	COG4774	siderophore transport
AV940_13850	COG4682	membrane
AV940_13865	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AV940_13870	COG0789	Transcriptional regulator
AV940_13885	COG0189	ligase activity
AV940_13900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AV940_13940	COG1960	acyl-CoA dehydrogenase activity
AV940_13970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AV940_13980	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AV940_14030	COG1607	acyl-coa hydrolase
AV940_14035	COG0826	peptidase U32
AV940_14100	COG0583	DNA-binding transcription factor activity
AV940_14115	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_14120	COG1733	regulation of RNA biosynthetic process
AV940_14135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AV940_14170	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_14180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV940_14185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV940_14200	COG0109	protoheme IX farnesyltransferase activity
AV940_14215	COG0583	DNA-binding transcription factor activity
AV940_14230	COG4221	oxidoreductase activity
AV940_14235	COG0693	protein deglycase activity
AV940_14255	COG2801	Transposase and inactivated derivatives
AV940_14295	COG1230	cation diffusion facilitator family transporter
AV940_14300	COG0789	Transcriptional regulator
AV940_14335	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AV940_14340	COG1335	isochorismatase
AV940_14345	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AV940_14365	COG4771	TonB-dependent receptor
AV940_14400	COG1566	PFAM secretion protein HlyD family protein
AV940_14405	COG1846	Transcriptional regulator
AV940_14415	COG1295	ribonuclease BN
AV940_14425	COG0514	ATP-dependent DNA helicase (RecQ)
AV940_14430	COG4681	YaeQ
AV940_14450	COG0583	DNA-binding transcription factor activity
AV940_14460	COG0484	heat shock protein binding
AV940_14465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AV940_14465	COG1017	nitric oxide dioxygenase activity
AV940_14480	COG3604	Transcriptional regulator
AV940_14505	COG4249	Peptidase C14 caspase catalytic subunit p20
AV940_14505	COG2319	Wd-40 repeat
AV940_14520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AV940_14540	COG1451	nucleotide metabolic process
AV940_14555	COG0653	protein targeting
AV940_14590	COG2133	pyrroloquinoline quinone binding
AV940_14600	COG0697	spore germination
AV940_14605	COG3813	Protein conserved in bacteria
AV940_14610	COG0513	Belongs to the DEAD box helicase family
AV940_14660	COG2814	Major facilitator Superfamily
AV940_14670	COG0656	L-ascorbic acid biosynthetic process
AV940_14725	COG2801	Transposase and inactivated derivatives
AV940_14765	COG0583	DNA-binding transcription factor activity
AV940_14785	COG1621	beta-fructofuranosidase activity
AV940_14790	COG2814	Major facilitator Superfamily
AV940_14800	COG1629	transport
AV940_14800	COG4206	TonB-dependent receptor
AV940_14825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV940_14830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AV940_14835	COG0006	proline dipeptidase activity
AV940_14850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV940_14855	COG1957	nucleoside hydrolase
AV940_14865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AV940_14870	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AV940_14875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV940_14895	COG3313	Fe-S protein
AV940_14935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV940_14940	COG0508	dehydrogenase complex catalyzes the overall conversion of
AV940_14945	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AV940_14950	COG2186	Transcriptional regulator
AV940_14975	COG4969	Belongs to the N-Me-Phe pilin family
AV940_14980	COG1459	type II secretion system
AV940_14990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AV940_14990	COG0237	dephospho-CoA kinase activity
AV940_14995	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AV940_15005	COG2988	succinylglutamate desuccinylase activity
AV940_15010	COG0494	nUDIX hydrolase
AV940_15020	COG0739	heme binding
AV940_15025	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AV940_15035	COG0849	cell division
AV940_15040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AV940_15045	COG1181	Belongs to the D-alanine--D-alanine ligase family
AV940_15050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AV940_15060	COG0772	Belongs to the SEDS family
AV940_15065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AV940_15075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AV940_15080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AV940_15085	COG0768	penicillin binding
AV940_15090	COG3116	cell division
AV940_15100	COG2001	Belongs to the MraZ family
AV940_15140	COG0678	peroxiredoxin activity
AV940_15140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AV940_15145	COG5001	Diguanylate cyclase
AV940_15145	COG4251	negative regulation of phosphorylation
AV940_15145	COG2203	Gaf domain
AV940_15145	COG3706	GGDEF domain
AV940_15155	COG2204	response regulator
AV940_15160	COG2198	Histidine kinase
AV940_15160	COG0784	Response regulator, receiver
AV940_15160	COG5002	protein histidine kinase activity
AV940_15180	COG0668	transmembrane transport
AV940_15185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AV940_15190	COG0189	ligase activity
AV940_15195	COG1678	Uncharacterized ACR, COG1678
AV940_15200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AV940_15220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AV940_15225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AV940_15230	COG0762	integral membrane protein
AV940_15245	COG0446	pyridine nucleotide-disulphide oxidoreductase
AV940_15245	COG1902	pentaerythritol trinitrate reductase activity
AV940_15260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AV940_15265	COG0625	glutathione transferase activity
AV940_15285	COG2963	transposase activity
AV940_15300	COG0083	homoserine kinase activity
AV940_15310	COG0583	DNA-binding transcription factor activity
AV940_15320	COG2197	response regulator
AV940_15325	COG4585	Histidine kinase
AV940_15345	COG0640	Transcriptional regulator
AV940_15355	COG0431	NADPH-dependent FMN reductase
AV940_15360	COG0798	PFAM Bile acid sodium symporter
AV940_15365	COG2201	protein-glutamate methylesterase activity
AV940_15370	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AV940_15375	COG0745	RESPONSE REGULATOR receiver
AV940_15380	COG5002	protein histidine kinase activity
AV940_15405	COG1748	Saccharopine dehydrogenase
AV940_15420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AV940_15425	COG3107	peptidoglycan biosynthetic process
AV940_15430	COG0792	nuclease activity
AV940_15440	COG2823	Periplasmic or secreted lipoprotein
AV940_15485	COG4585	Histidine kinase
AV940_15490	COG2197	response regulator
AV940_15495	COG4771	TonB-dependent receptor
AV940_15505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AV940_15510	COG0372	Belongs to the citrate synthase family
AV940_15520	COG2828	Protein conserved in bacteria
AV940_15525	COG2203	Gaf domain
AV940_15525	COG2199	diguanylate cyclase activity
AV940_15570	COG2198	Histidine kinase
AV940_15570	COG5002	protein histidine kinase activity
AV940_15570	COG0784	Response regulator, receiver
AV940_15575	COG0070	glutamate synthase
AV940_15575	COG0069	glutamate synthase activity
AV940_15575	COG0067	glutamate synthase
AV940_15580	COG0493	'glutamate synthase
AV940_15590	COG1476	TRANSCRIPTIONal
AV940_15595	COG3866	Pectate lyase
AV940_15615	COG3866	Pectate lyase
AV940_15630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AV940_15645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AV940_15665	COG0739	heme binding
AV940_15670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AV940_15680	COG0738	Major facilitator superfamily
AV940_15685	COG3659	wide pore channel activity
AV940_15690	COG1902	pentaerythritol trinitrate reductase activity
AV940_15700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AV940_15705	COG0625	glutathione transferase activity
AV940_15725	COG2894	cell division
AV940_15730	COG0850	regulation of cytokinetic process
AV940_15770	COG1914	H( )-stimulated, divalent metal cation uptake system
AV940_15775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AV940_15795	COG0174	glutamine synthetase
AV940_15805	COG3852	Histidine kinase
AV940_15815	COG3437	response regulator, receiver
AV940_15820	COG0204	Acyl-transferase
AV940_15835	COG3706	GGDEF domain
AV940_15850	COG0525	valine-tRNA ligase activity
AV940_15855	COG2927	DNA polymerase III (CHI subunit)
AV940_15860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV940_15865	COG0795	lipopolysaccharide-transporting ATPase activity
AV940_15870	COG0795	lipopolysaccharide-transporting ATPase activity
AV940_15920	COG4264	IucA IucC family
AV940_15925	COG0318	PFAM AMP-dependent synthetase and ligase
AV940_15935	COG1082	Xylose isomerase domain protein TIM barrel
AV940_16015	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AV940_16075	COG4191	Histidine kinase
AV940_16085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AV940_16115	COG3706	GGDEF domain
AV940_16120	COG3706	GGDEF domain
AV940_16160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AV940_16165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AV940_16170	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AV940_16180	COG0535	radical SAM domain protein
AV940_16210	COG2205	protein histidine kinase activity
AV940_16210	COG0784	Response regulator, receiver
AV940_16220	COG3901	Regulator of nitric oxide reductase transcription
AV940_16220	COG0348	domain, Protein
AV940_16225	COG1012	belongs to the aldehyde dehydrogenase family
AV940_16230	COG2197	response regulator
AV940_16235	COG4585	Histidine kinase
AV940_16265	COG4771	TonB-dependent receptor
AV940_16270	COG1858	cytochrome C peroxidase
AV940_16300	COG1028	Short-chain dehydrogenase reductase Sdr
AV940_16310	COG1917	Cupin 2, conserved barrel domain protein
AV940_16315	COG2271	Major facilitator Superfamily
AV940_16335	COG1716	ATPase activity
AV940_16370	COG1357	PFAM Pentapeptide repeats (8 copies)
AV940_16370	COG0515	serine threonine protein kinase
AV940_16385	COG1716	ATPase activity
AV940_16385	COG0842	Transport permease protein
AV940_16385	COG1131	(ABC) transporter
AV940_16390	COG0513	Belongs to the DEAD box helicase family
AV940_16395	COG0800	Aldolase
AV940_16400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV940_16405	COG2186	Transcriptional regulator
AV940_16415	COG3264	Mechanosensitive ion channel
AV940_16415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AV940_16450	COG3568	Endonuclease Exonuclease Phosphatase
AV940_16465	COG0730	response to heat
AV940_16485	COG4191	Histidine kinase
AV940_16495	COG0417	DNA replication proofreading
AV940_16545	COG1309	transcriptional regulator
AV940_16560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV940_16570	COG1573	uracil-dna glycosylase
AV940_16575	COG5001	Diguanylate cyclase
AV940_16575	COG3300	MHYT domain
AV940_16595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV940_16600	COG4771	TonB-dependent receptor
AV940_16625	COG1842	Phage shock protein A
AV940_16635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV940_16660	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AV940_16665	COG0204	Acyl-transferase
AV940_16670	COG0204	Acyl-transferase
AV940_16675	COG0668	transmembrane transport
AV940_16690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AV940_16695	COG0733	neurotransmitter:sodium symporter activity
AV940_16710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AV940_16725	COG0716	FMN binding
AV940_16735	COG0848	biopolymer transport protein
AV940_16745	COG0457	Tetratricopeptide repeat
AV940_16775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AV940_16780	COG0702	epimerase
AV940_16795	COG5001	Diguanylate cyclase
AV940_16795	COG5002	protein histidine kinase activity
AV940_16805	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AV940_16810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV940_16820	COG0583	DNA-binding transcription factor activity
AV940_16825	COG0121	glutamine amidotransferase
AV940_16840	COG1522	sequence-specific DNA binding
AV940_16855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AV940_16865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AV940_16875	COG1477	protein flavinylation
AV940_16880	COG2871	sodium ion transport
AV940_16885	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV940_16890	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV940_16895	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AV940_16900	COG1805	sodium ion transport
AV940_16910	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AV940_16915	COG0545	Peptidyl-prolyl cis-trans isomerase
AV940_16920	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AV940_16930	COG0039	L-malate dehydrogenase activity
AV940_16935	COG1438	arginine binding
AV940_16965	COG0572	uridine kinase
AV940_16970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AV940_16985	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AV940_16995	COG0745	RESPONSE REGULATOR receiver
AV940_16995	COG3706	GGDEF domain
AV940_17005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AV940_17005	COG0517	IMP dehydrogenase activity
AV940_17010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV940_17030	COG0189	ligase activity
AV940_17040	COG0189	ligase activity
AV940_17040	COG4067	protein conserved in archaea
AV940_17055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AV940_17070	COG1283	sodium-dependent phosphate transmembrane transporter activity
AV940_17075	COG0667	Aldo Keto reductase
AV940_17090	COG0753	catalase activity
AV940_17140	COG0583	DNA-binding transcription factor activity
AV940_17155	COG1216	Glycosyl transferase, family 2
AV940_17155	COG0438	transferase activity, transferring glycosyl groups
AV940_17185	COG1216	Glycosyl transferase, family 2
AV940_17190	COG1216	Glycosyl transferase, family 2
AV940_17200	COG1215	transferase activity, transferring glycosyl groups
AV940_17215	COG0110	maltose O-acetyltransferase activity
AV940_17225	COG1216	Glycosyl transferase, family 2
AV940_17240	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AV940_17240	COG0662	Cupin 2, conserved barrel domain protein
AV940_17250	COG0202	RNA polymerase activity
AV940_17270	COG0201	protein transport
AV940_17290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AV940_17325	COG5002	protein histidine kinase activity
AV940_17325	COG0784	Response regulator, receiver
AV940_17345	COG0557	exoribonuclease II activity
AV940_17360	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AV940_17375	COG0543	2 iron, 2 sulfur cluster binding
AV940_17380	COG2234	aminopeptidase activity
AV940_17400	COG1271	oxidase subunit
AV940_17405	COG1294	oxidase, subunit
AV940_17410	COG0840	transmembrane signaling receptor activity
AV940_17415	COG1522	sequence-specific DNA binding
AV940_17430	COG1278	Cold shock
AV940_17435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV940_17455	COG0339	signal peptide processing
AV940_17460	COG2201	protein-glutamate methylesterase activity
AV940_17470	COG4191	Histidine kinase
AV940_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV940_17480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AV940_17485	COG0243	molybdopterin cofactor binding
AV940_17490	COG4946	Tricorn protease homolog
AV940_17490	COG0793	Belongs to the peptidase S41A family
AV940_17530	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AV940_17535	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AV940_17540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AV940_17555	COG0281	malic enzyme
AV940_17560	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AV940_17565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AV940_17595	COG0456	acetyltransferase
AV940_17605	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV940_17610	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AV940_17615	COG2177	Part of the ABC transporter FtsEX involved in
AV940_17620	COG2884	Cell division ATP-binding protein ftsE
AV940_17625	COG0552	protein localization to endoplasmic reticulum
AV940_17630	COG0742	ribosomal rna small subunit methyltransferase
AV940_17640	COG2095	MarC family integral membrane protein
AV940_17660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AV940_17665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AV940_17675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AV940_17690	COG0076	glutamate decarboxylase activity
AV940_17695	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AV940_17705	COG0842	Transport permease protein
AV940_17710	COG1131	(ABC) transporter
AV940_17715	COG0745	RESPONSE REGULATOR receiver
AV940_17720	COG2205	protein histidine kinase activity
AV940_17725	COG4774	siderophore transport
AV940_17745	COG1253	flavin adenine dinucleotide binding
AV940_17750	COG0701	Predicted permease
AV940_17755	COG1966	Carbon starvation protein
AV940_17805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AV940_17810	COG0049	tRNA binding
AV940_17815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AV940_17820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AV940_17825	COG0085	RNA polymerase activity
AV940_17830	COG0222	ribosome binding
AV940_17835	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AV940_17840	COG0081	regulation of translation
AV940_17845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AV940_17850	COG0250	Participates in transcription elongation, termination and antitermination
AV940_17855	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AV940_17865	COG1132	(ABC) transporter
AV940_17870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AV940_17875	COG3590	peptidase
AV940_17885	COG0513	Belongs to the DEAD box helicase family
AV940_17890	COG0418	dihydroorotase activity
AV940_17900	COG3040	lipid binding
AV940_17905	COG4989	oxidoreductase activity
AV940_17910	COG0346	lactoylglutathione lyase activity
AV940_17925	COG0302	gtp cyclohydrolase
AV940_17945	COG2957	Belongs to the agmatine deiminase family
AV940_17950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AV940_17965	COG3306	glycosyltransferase involved in LPS biosynthesis
AV940_17970	COG1201	RNA secondary structure unwinding
AV940_17980	COG1793	dna ligase
AV940_17990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AV940_18005	COG0625	glutathione transferase activity
AV940_18020	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AV940_18025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AV940_18035	COG1012	belongs to the aldehyde dehydrogenase family
AV940_18050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AV940_18055	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AV940_18060	COG0330	HflC and HflK could
AV940_18065	COG0330	HflC and HflK could
AV940_18070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AV940_18075	COG1923	regulation of RNA biosynthetic process
AV940_18080	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AV940_18095	COG0802	atpase or kinase
AV940_18100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AV940_18100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AV940_18105	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AV940_18115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AV940_18120	COG2816	NAD+ diphosphatase activity
AV940_18125	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AV940_18130	COG0735	belongs to the Fur family
AV940_18140	COG0432	Pfam Uncharacterised protein family UPF0047
AV940_18150	COG0305	Participates in initiation and elongation during chromosome replication
AV940_18175	COG2258	MOSC domain
AV940_18205	COG5002	protein histidine kinase activity
AV940_18215	COG0840	transmembrane signaling receptor activity
AV940_18220	COG4191	Histidine kinase
AV940_18220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AV940_18230	COG1609	Transcriptional regulator
AV940_18235	COG2211	Major facilitator Superfamily
AV940_18240	COG2723	6-phospho-beta-galactosidase activity
AV940_18250	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AV940_18255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AV940_18260	COG4558	Periplasmic binding protein
AV940_18270	COG4206	TonB-dependent receptor
AV940_18280	COG1472	Belongs to the glycosyl hydrolase 3 family
AV940_18295	COG2855	membrane
AV940_18300	COG2175	clavaminate synthase activity
AV940_18305	COG0656	L-ascorbic acid biosynthetic process
AV940_18325	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AV940_18330	COG1230	cation diffusion facilitator family transporter
AV940_18365	COG4771	TonB-dependent receptor
AV940_18370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AV940_18375	COG4988	ABC transporter
AV940_18385	COG1294	oxidase, subunit
AV940_18400	COG2204	response regulator
AV940_18435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AV940_18460	COG4319	ketosteroid isomerase
AV940_18500	COG3237	CsbD-like
AV940_18545	COG2267	carboxylic ester hydrolase activity
AV940_18570	COG3038	cytochrome b561
AV940_18575	COG2353	YceI-like domain
AV940_18580	COG1252	NADH dehydrogenase
AV940_18610	COG2130	NADP-dependent
AV940_18615	COG5001	Diguanylate cyclase
AV940_18615	COG4251	negative regulation of phosphorylation
AV940_18615	COG3706	GGDEF domain
AV940_18615	COG2203	Gaf domain
AV940_18635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AV940_18645	COG4181	ATPase activity
AV940_18665	COG0523	cobalamin synthesis protein
AV940_18680	COG4771	TonB-dependent receptor
AV940_18685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AV940_18710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AV940_18715	COG1349	DNA-binding transcription factor activity
AV940_18730	COG0697	spore germination
AV940_18735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AV940_18740	COG4977	sequence-specific DNA binding
AV940_18750	COG1166	arginine decarboxylase activity
AV940_18760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AV940_18765	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV940_18770	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AV940_18780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AV940_18790	COG0523	cobalamin synthesis protein
AV940_18820	COG4232	protein-disulfide reductase activity
AV940_18825	COG0739	heme binding
AV940_18830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AV940_18835	COG0511	ligase activity, forming carbon-carbon bonds
AV940_18840	COG0439	Biotin carboxylase
AV940_18860	COG2176	DNA-directed DNA polymerase activity
AV940_18880	COG0154	amidase activity
AV940_18895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AV940_18900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AV940_18915	COG0151	Belongs to the GarS family
AV940_18925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AV940_18935	COG3954	Phosphoribulokinase
AV940_18940	COG2233	PERMEase
AV940_18955	COG0745	RESPONSE REGULATOR receiver
AV940_18975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AV940_18985	COG3031	protein transport across the cell outer membrane
AV940_18995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AV940_19000	COG1459	type II secretion system
AV940_19005	COG2165	general secretion pathway protein
AV940_19015	COG2165	general secretion pathway protein
AV940_19020	COG4795	General secretion pathway protein
AV940_19025	COG3156	type II secretion system protein K
AV940_19035	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AV940_19045	COG1234	tRNA 3'-trailer cleavage
AV940_19050	COG1012	belongs to the aldehyde dehydrogenase family
AV940_19060	COG1011	Hydrolase
AV940_19065	COG0494	nUDIX hydrolase
AV940_19070	COG1218	3'(2'),5'-bisphosphate nucleotidase
AV940_19085	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AV940_19095	COG3089	Belongs to the UPF0270 family
AV940_19100	COG0429	hydrolase of the alpha beta-hydrolase fold
AV940_19110	COG0488	(ABC) transporter
AV940_19135	COG0545	Peptidyl-prolyl cis-trans isomerase
AV940_19145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AV940_19150	COG2183	response to ionizing radiation
AV940_19165	COG0596	Alpha beta hydrolase
AV940_19170	COG1040	competence protein
AV940_19190	COG1794	racemase activity, acting on amino acids and derivatives
AV940_19205	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AV940_19210	COG0534	Mate efflux family protein
AV940_19225	COG1999	signal sequence binding
AV940_19230	COG0109	protoheme IX farnesyltransferase activity
AV940_19235	COG1612	heme a metabolic process
AV940_19260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AV940_19265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AV940_19270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AV940_19270	COG1565	acr, cog1565
AV940_19300	COG0129	dihydroxy-acid dehydratase activity
AV940_19305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AV940_19315	COG0606	chelatase, subunit chli
AV940_19320	COG0583	DNA-binding transcription factor activity
AV940_19330	COG2814	Major facilitator Superfamily
AV940_19340	COG0729	surface antigen
AV940_19345	COG2911	Protein conserved in bacteria
AV940_19370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AV940_19380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AV940_19400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AV940_19450	COG0425	Belongs to the sulfur carrier protein TusA family
AV940_19465	COG1561	YicC-like family, N-terminal region
AV940_19500	COG2211	Major facilitator Superfamily
AV940_19505	COG1609	Transcriptional regulator
AV940_19520	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AV940_19520	COG2199	diguanylate cyclase activity
AV940_19550	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AV940_19570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AV940_19575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AV940_19595	COG1475	DNA binding
AV940_19600	COG1192	Involved in chromosome partitioning
AV940_19625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AV940_19630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AV940_19640	COG0706	membrane insertase activity
AV940_19645	COG0594	ribonuclease P activity
AV940_19650	COG0230	Belongs to the bacterial ribosomal protein bL34 family