locus-tag	class	description
BM527_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BM527_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BM527_00020	COG0187	DNA topoisomerase II activity
BM527_00050	COG2818	Glycosylase
BM527_00060	COG3078	GTPase activator activity
BM527_00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM527_00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BM527_00090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BM527_00095	COG0569	domain protein
BM527_00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BM527_00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BM527_00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BM527_00120	COG0758	DNA mediated transformation
BM527_00135	COG0009	L-threonylcarbamoyladenylate synthase
BM527_00140	COG0408	coproporphyrinogen oxidase activity
BM527_00145	COG3047	cAMP biosynthetic process
BM527_00160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BM527_00240	COG2234	aminopeptidase activity
BM527_00255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BM527_00280	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM527_00315	COG3642	lipopolysaccharide core region biosynthetic process
BM527_00320	COG0859	PFAM glycosyl transferase family 9
BM527_00350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM527_00365	COG3161	chorismate lyase activity
BM527_00370	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BM527_00380	COG0210	DNA helicase
BM527_00425	COG0730	response to heat
BM527_00450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM527_00455	COG4988	ABC transporter
BM527_00465	COG1271	oxidase subunit
BM527_00480	COG0425	Belongs to the sulfur carrier protein TusA family
BM527_00480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM527_00490	COG0450	alkyl hydroperoxide reductase
BM527_00500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BM527_00560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM527_00565	COG1129	ABC transporter
BM527_00565	COG0842	Transport permease protein
BM527_00570	COG0842	Transport permease protein
BM527_00590	COG0583	DNA-binding transcription factor activity
BM527_00600	COG3106	COG3106 Predicted ATPase
BM527_00615	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BM527_00635	COG0352	thiamine-phosphate diphosphorylase activity
BM527_00645	COG3071	HemY protein
BM527_00650	COG2959	enzyme of heme biosynthesis
BM527_00660	COG0181	hydroxymethylbilane synthase activity
BM527_00665	COG3706	GGDEF domain
BM527_00665	COG0745	RESPONSE REGULATOR receiver
BM527_00675	COG0194	GDP metabolic process
BM527_00685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM527_00695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM527_00700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BM527_00710	COG0678	peroxiredoxin activity
BM527_00725	COG1178	ABC-type Fe3 transport system permease component
BM527_00730	COG3842	ATPase activity
BM527_00735	COG0668	transmembrane transport
BM527_00740	COG2081	HI0933 family
BM527_00755	COG2200	EAL domain
BM527_00760	COG3706	GGDEF domain
BM527_00765	COG0583	DNA-binding transcription factor activity
BM527_00775	COG2076	Multidrug Resistance protein
BM527_00790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM527_00805	COG0427	acetyl-CoA hydrolase
BM527_00810	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM527_00830	COG3064	Membrane
BM527_00840	COG5001	Diguanylate cyclase
BM527_00840	COG5002	protein histidine kinase activity
BM527_00855	COG0514	ATP-dependent DNA helicase (RecQ)
BM527_00860	COG2050	protein possibly involved in aromatic compounds catabolism
BM527_00865	COG2239	Acts as a magnesium transporter
BM527_00870	COG2962	Rard protein
BM527_00875	COG3706	GGDEF domain
BM527_00880	COG0210	DNA helicase
BM527_00890	COG1011	Hydrolase
BM527_00905	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BM527_00910	COG0019	diaminopimelate decarboxylase activity
BM527_00940	COG0163	prenyltransferase activity
BM527_00945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM527_00955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BM527_00975	COG1077	Cell shape determining protein MreB Mrl
BM527_00980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BM527_00985	COG2814	Major facilitator Superfamily
BM527_00990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM527_01015	COG1085	galactose-1-phosphate uridylyltransferase
BM527_01020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BM527_01030	COG0629	single-stranded DNA binding
BM527_01115	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BM527_01150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM527_01155	COG3250	beta-galactosidase activity
BM527_01170	COG1349	DNA-binding transcription factor activity
BM527_01225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM527_01230	COG1459	type II secretion system
BM527_01275	COG1077	Cell shape determining protein MreB Mrl
BM527_01280	COG1792	Involved in formation and maintenance of cell shape
BM527_01285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BM527_01290	COG0424	maF-like protein
BM527_01295	COG1530	ribonuclease E activity
BM527_01305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM527_01310	COG0312	modulator of DNA gyrase
BM527_01315	COG3028	Belongs to the UPF0307 family
BM527_01320	COG0312	modulator of DNA gyrase
BM527_01335	COG0745	RESPONSE REGULATOR receiver
BM527_01340	COG4191	Histidine kinase
BM527_01340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM527_01345	COG0297	glycogen (starch) synthase activity
BM527_01355	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BM527_01365	COG1194	a g-specific adenine glycosylase
BM527_01390	COG0745	RESPONSE REGULATOR receiver
BM527_01400	COG0835	chemotaxis
BM527_01415	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM527_01430	COG0745	RESPONSE REGULATOR receiver
BM527_01435	COG2198	Histidine kinase
BM527_01435	COG0643	Histidine kinase
BM527_01440	COG0835	chemotaxis
BM527_01460	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BM527_01465	COG2201	protein-glutamate methylesterase activity
BM527_01495	COG5002	protein histidine kinase activity
BM527_01510	COG1609	Transcriptional regulator
BM527_01515	COG0673	inositol 2-dehydrogenase activity
BM527_01525	COG2211	Major facilitator Superfamily
BM527_01530	COG1082	Xylose isomerase domain protein TIM barrel
BM527_01550	COG1454	alcohol dehydrogenase
BM527_01630	COG0089	rRNA binding
BM527_01640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BM527_01650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BM527_01665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BM527_01670	COG0438	transferase activity, transferring glycosyl groups
BM527_01680	COG1519	Transferase
BM527_01720	COG0788	formyltetrahydrofolate deformylase activity
BM527_01730	COG1643	Atp-dependent helicase
BM527_01740	COG2951	lytic endotransglycosylase activity
BM527_01745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BM527_01755	COG2354	Protein conserved in bacteria
BM527_01770	COG0004	ammonium transporteR
BM527_01775	COG0405	Gamma-glutamyltransferase
BM527_01780	COG2837	iron assimilation
BM527_01795	COG0540	Belongs to the ATCase OTCase family
BM527_01820	COG5002	protein histidine kinase activity
BM527_01820	COG2205	protein histidine kinase activity
BM527_01820	COG0784	Response regulator, receiver
BM527_01835	COG5001	Diguanylate cyclase
BM527_01845	COG1012	belongs to the aldehyde dehydrogenase family
BM527_01855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BM527_01870	COG0180	Tryptophanyl-tRNA synthetase
BM527_01875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BM527_01895	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BM527_01905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BM527_01940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BM527_01945	COG0281	malic enzyme
BM527_01955	COG0625	glutathione transferase activity
BM527_01965	COG1309	transcriptional regulator
BM527_01975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BM527_01975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BM527_01985	COG0137	argininosuccinate synthase activity
BM527_02005	COG1803	Methylglyoxal synthase
BM527_02015	COG0745	RESPONSE REGULATOR receiver
BM527_02020	COG2205	protein histidine kinase activity
BM527_02025	COG2267	carboxylic ester hydrolase activity
BM527_02030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BM527_02040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BM527_02050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM527_02055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BM527_02060	COG4942	peptidase
BM527_02065	COG2861	carbohydrate metabolic process
BM527_02090	COG1162	GTPase activity
BM527_02095	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BM527_02105	COG0028	Belongs to the TPP enzyme family
BM527_02115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BM527_02120	COG1288	antiporter activity
BM527_02125	COG4206	TonB-dependent receptor
BM527_02145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BM527_02150	COG0805	protein transport
BM527_02160	COG0084	hydrolase, TatD family'
BM527_02165	COG2203	Gaf domain
BM527_02165	COG3706	GGDEF domain
BM527_02165	COG4251	negative regulation of phosphorylation
BM527_02165	COG5001	Diguanylate cyclase
BM527_02175	COG0248	Ppx GppA phosphatase
BM527_02180	COG0513	Belongs to the DEAD box helicase family
BM527_02185	COG3118	belongs to the thioredoxin family
BM527_02190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BM527_02205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BM527_02215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BM527_02230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BM527_02240	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BM527_02255	COG0783	Belongs to the Dps family
BM527_02260	COG2133	pyrroloquinoline quinone binding
BM527_02265	COG1506	peptidase
BM527_02265	COG0823	Involved in the tonB-independent uptake of proteins
BM527_02265	COG4946	Tricorn protease homolog
BM527_02275	COG3118	belongs to the thioredoxin family
BM527_02290	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BM527_02300	COG1012	belongs to the aldehyde dehydrogenase family
BM527_02325	COG1757	Na H antiporter
BM527_02340	COG3876	Protein conserved in bacteria
BM527_02345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BM527_02365	COG0346	lactoylglutathione lyase activity
BM527_02390	COG2824	Alkylphosphonate utilization operon protein PhnA
BM527_02395	COG0454	-acetyltransferase
BM527_02420	COG4115	mRNA cleavage
BM527_02425	COG2161	toxin-antitoxin pair type II binding
BM527_02435	COG3093	addiction module antidote protein HigA
BM527_02460	COG0183	Belongs to the thiolase family
BM527_02465	COG1024	Enoyl-CoA hydratase
BM527_02465	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM527_02475	COG0006	proline dipeptidase activity
BM527_02485	COG0142	geranyltranstransferase activity
BM527_02515	COG4942	peptidase
BM527_02515	COG1388	LysM domain
BM527_02520	COG1238	metal cluster binding
BM527_02530	COG0585	pseudouridine synthase activity
BM527_02535	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BM527_02545	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BM527_02555	COG0840	transmembrane signaling receptor activity
BM527_02570	COG3025	triphosphatase activity
BM527_02580	COG3066	DNA modification
BM527_02585	COG0494	nUDIX hydrolase
BM527_02595	COG0730	response to heat
BM527_02600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BM527_02605	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BM527_02610	COG2201	protein-glutamate methylesterase activity
BM527_02615	COG0745	RESPONSE REGULATOR receiver
BM527_02615	COG3706	GGDEF domain
BM527_02625	COG2211	Major facilitator Superfamily
BM527_02640	COG0564	pseudouridine synthase activity
BM527_02645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BM527_02650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BM527_02660	COG1648	precorrin-2 dehydrogenase activity
BM527_02660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BM527_02665	COG0513	Belongs to the DEAD box helicase family
BM527_02680	COG1538	Outer membrane efflux protein
BM527_02685	COG0494	nUDIX hydrolase
BM527_02695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BM527_02700	COG3150	esterase
BM527_02705	COG0187	DNA topoisomerase II activity
BM527_02715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BM527_02735	COG1509	lysine 2,3-aminomutase activity
BM527_02745	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BM527_02765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM527_02780	COG0271	Belongs to the BolA IbaG family
BM527_02785	COG0671	phosphoesterase, PA-phosphatase related
BM527_02795	COG0583	DNA-binding transcription factor activity
BM527_02800	COG0009	L-threonylcarbamoyladenylate synthase
BM527_02805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BM527_02810	COG3002	Belongs to the UPF0753 family
BM527_02820	COG0659	secondary active sulfate transmembrane transporter activity
BM527_02825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM527_02840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM527_02845	COG4206	TonB-dependent receptor
BM527_02855	COG0348	domain, Protein
BM527_02870	COG1960	acyl-CoA dehydrogenase activity
BM527_02875	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_02885	COG4948	Mandelate Racemase Muconate Lactonizing
BM527_02900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM527_02905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM527_02925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BM527_02930	COG0358	DNA primase activity
BM527_02955	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BM527_02960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM527_02975	COG0537	adenosine 5'-monophosphoramidase activity
BM527_02990	COG3135	benzoate transporter
BM527_02995	COG1396	sequence-specific DNA binding
BM527_03000	COG2974	May be involved in recombination
BM527_03005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM527_03005	COG4191	Histidine kinase
BM527_03010	COG0745	RESPONSE REGULATOR receiver
BM527_03015	COG5002	protein histidine kinase activity
BM527_03040	COG0811	peptide transport
BM527_03045	COG0811	peptide transport
BM527_03050	COG0848	biopolymer transport protein
BM527_03055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BM527_03065	COG3437	response regulator, receiver
BM527_03070	COG5002	protein histidine kinase activity
BM527_03070	COG0784	Response regulator, receiver
BM527_03070	COG2205	protein histidine kinase activity
BM527_03080	COG0318	PFAM AMP-dependent synthetase and ligase
BM527_03095	COG2133	pyrroloquinoline quinone binding
BM527_03100	COG1049	propionate catabolic process, 2-methylcitrate cycle
BM527_03110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM527_03115	COG4999	Histidine kinase
BM527_03115	COG3850	Histidine kinase
BM527_03115	COG3437	response regulator, receiver
BM527_03115	COG2205	protein histidine kinase activity
BM527_03145	COG0527	aspartate kinase activity
BM527_03160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BM527_03165	COG2967	ApaG domain
BM527_03175	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BM527_03180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM527_03185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BM527_03190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BM527_03200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM527_03205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BM527_03220	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BM527_03235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BM527_03240	COG3956	TIGRFAM MazG family protein
BM527_03265	COG4771	TonB-dependent receptor
BM527_03280	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_03290	COG0318	PFAM AMP-dependent synthetase and ligase
BM527_03310	COG0463	Glycosyl transferase, family 2
BM527_03335	COG0745	RESPONSE REGULATOR receiver
BM527_03350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BM527_03355	COG0723	plastoquinol--plastocyanin reductase activity
BM527_03360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BM527_03365	COG2857	Cytochrome c1
BM527_03370	COG0625	glutathione transferase activity
BM527_03375	COG2969	positive regulation of protein catabolic process
BM527_03380	COG2239	Acts as a magnesium transporter
BM527_03385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM527_03395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BM527_03405	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BM527_03410	COG1137	ATPase activity
BM527_03415	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BM527_03425	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BM527_03440	COG1127	ABC transporter
BM527_03445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BM527_03450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM527_03455	COG2854	intermembrane phospholipid transfer
BM527_03465	COG5007	Belongs to the BolA IbaG family
BM527_03475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM527_03480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BM527_03490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BM527_03540	COG3300	MHYT domain
BM527_03540	COG5001	Diguanylate cyclase
BM527_03555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM527_03570	COG4771	TonB-dependent receptor
BM527_03575	COG0697	spore germination
BM527_03580	COG0784	Response regulator, receiver
BM527_03580	COG2205	protein histidine kinase activity
BM527_03605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BM527_03615	COG0126	phosphoglycerate kinase activity
BM527_03620	COG3588	fructose-bisphosphate aldolase
BM527_03625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BM527_03635	COG0745	RESPONSE REGULATOR receiver
BM527_03665	COG4946	Tricorn protease homolog
BM527_03665	COG1506	peptidase
BM527_03665	COG0823	Involved in the tonB-independent uptake of proteins
BM527_03670	COG0248	Ppx GppA phosphatase
BM527_03675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BM527_03685	COG0573	inorganic phosphate transmembrane transporter activity
BM527_03695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BM527_03705	COG0306	phosphate transporter
BM527_03715	COG0583	DNA-binding transcription factor activity
BM527_03725	COG1272	protein, Hemolysin III
BM527_03730	COG1846	Transcriptional regulator
BM527_03735	COG1764	response to oxidative stress
BM527_03750	COG1739	Uncharacterized protein family UPF0029
BM527_03765	COG0419	ATPase involved in DNA repair
BM527_03770	COG1621	beta-fructofuranosidase activity
BM527_03780	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BM527_03795	COG2188	Transcriptional regulator
BM527_03805	COG2986	histidine ammonia-lyase
BM527_03830	COG0488	(ABC) transporter
BM527_03900	COG2205	protein histidine kinase activity
BM527_03900	COG2198	Histidine kinase
BM527_03900	COG0784	Response regulator, receiver
BM527_03900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM527_03910	COG2204	response regulator
BM527_03935	COG0668	transmembrane transport
BM527_03945	COG2814	Major facilitator Superfamily
BM527_03980	COG1380	Effector of murein hydrolase LrgA
BM527_03985	COG1346	cytolysis
BM527_04015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM527_04020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BM527_04025	COG0513	Belongs to the DEAD box helicase family
BM527_04040	COG3409	Peptidoglycan-binding domain 1 protein
BM527_04040	COG3267	Type II secretory pathway component ExeA
BM527_04055	COG0066	3-isopropylmalate dehydratase activity
BM527_04065	COG0473	3-isopropylmalate dehydrogenase activity
BM527_04070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BM527_04090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BM527_04105	COG4555	ABC transporter
BM527_04110	COG1668	transmembrane transport
BM527_04130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM527_04135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM527_04140	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BM527_04150	COG1138	Cytochrome C-type biogenesis protein
BM527_04170	COG2853	Lipoprotein
BM527_04175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BM527_04185	COG3104	oligopeptide transport
BM527_04215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BM527_04220	COG1215	transferase activity, transferring glycosyl groups
BM527_04230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BM527_04235	COG1596	polysaccharide export
BM527_04235	COG1555	photosystem II stabilization
BM527_04240	COG0473	3-isopropylmalate dehydrogenase activity
BM527_04255	COG1611	Belongs to the LOG family
BM527_04260	COG3706	GGDEF domain
BM527_04260	COG0745	RESPONSE REGULATOR receiver
BM527_04300	COG3098	single-species biofilm formation
BM527_04305	COG0564	pseudouridine synthase activity
BM527_04320	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BM527_04325	COG0024	Methionine aminopeptidase
BM527_04330	COG0052	Belongs to the universal ribosomal protein uS2 family
BM527_04340	COG0528	UMP kinase activity
BM527_04350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BM527_04355	COG0575	Belongs to the CDS family
BM527_04380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM527_04400	COG0587	DNA-directed DNA polymerase activity
BM527_04405	COG0825	malonyl-CoA metabolic process
BM527_04410	COG0037	tRNA processing
BM527_04430	COG0590	tRNA wobble adenosine to inosine editing
BM527_04440	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BM527_04440	COG0047	phosphoribosylformylglycinamidine synthase activity
BM527_04450	COG2840	Smr protein MutS2
BM527_04475	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BM527_04480	COG0732	type I restriction modification DNA specificity domain
BM527_04495	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BM527_04590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM527_04595	COG4566	intracellular signal transduction
BM527_04635	COG0784	Response regulator, receiver
BM527_04635	COG0835	chemotaxis
BM527_04640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BM527_04645	COG1815	bacterial-type flagellum-dependent cell motility
BM527_04650	COG1558	bacterial-type flagellum-dependent cell motility
BM527_04655	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BM527_04660	COG1749	Flagellar hook protein flgE
BM527_04665	COG4787	bacterial-type flagellum-dependent cell motility
BM527_04670	COG4786	Flagellar basal body rod
BM527_04685	COG1705	Flagellar rod assembly protein muramidase FlgJ
BM527_04685	COG3951	Flagellar rod assembly protein muramidase FlgJ
BM527_04690	COG1256	bacterial-type flagellum assembly
BM527_04710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM527_04715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BM527_04725	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BM527_04740	COG1086	Polysaccharide biosynthesis protein
BM527_04745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM527_04750	COG1083	cytidylyl-transferase
BM527_04755	COG2089	acid synthase
BM527_04775	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_04880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM527_04890	COG2204	response regulator
BM527_04895	COG3852	Histidine kinase
BM527_04900	COG2204	response regulator
BM527_04905	COG1677	Flagellar hook-basal body complex protein FliE
BM527_04910	COG1766	The M ring may be actively involved in energy transduction
BM527_04915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BM527_04965	COG1987	bacterial-type flagellum assembly
BM527_04980	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BM527_04990	COG0455	bacterial-type flagellum organization
BM527_05005	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BM527_05010	COG2198	Histidine kinase
BM527_05010	COG0643	Histidine kinase
BM527_05015	COG2201	protein-glutamate methylesterase activity
BM527_05020	COG1192	Involved in chromosome partitioning
BM527_05030	COG0835	chemotaxis
BM527_05045	COG1410	methionine synthase
BM527_05045	COG0646	methionine synthase
BM527_05050	COG0646	methionine synthase
BM527_05050	COG1410	methionine synthase
BM527_05060	COG3123	guanosine phosphorylase activity
BM527_05065	COG0583	DNA-binding transcription factor activity
BM527_05070	COG0583	DNA-binding transcription factor activity
BM527_05080	COG0659	secondary active sulfate transmembrane transporter activity
BM527_05095	COG3590	peptidase
BM527_05110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BM527_05130	COG1607	acyl-coa hydrolase
BM527_05140	COG5016	pyruvate
BM527_05140	COG0511	ligase activity, forming carbon-carbon bonds
BM527_05145	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BM527_05150	COG4172	Belongs to the ABC transporter superfamily
BM527_05160	COG4171	peptide transport system, permease
BM527_05165	COG4168	peptide transport system, permease
BM527_05170	COG0747	negative chemotaxis
BM527_05175	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BM527_05180	COG1842	Phage shock protein A
BM527_05210	COG0625	glutathione transferase activity
BM527_05215	COG1522	sequence-specific DNA binding
BM527_05220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BM527_05280	COG0811	peptide transport
BM527_05285	COG0811	peptide transport
BM527_05290	COG0848	biopolymer transport protein
BM527_05345	COG0456	acetyltransferase
BM527_05355	COG0583	DNA-binding transcription factor activity
BM527_05360	COG2814	Major facilitator Superfamily
BM527_05365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM527_05370	COG0656	L-ascorbic acid biosynthetic process
BM527_05395	COG1846	Transcriptional regulator
BM527_05430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BM527_05550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BM527_05555	COG2204	response regulator
BM527_05560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BM527_05575	COG0681	Belongs to the peptidase S26 family
BM527_05605	COG0758	DNA mediated transformation
BM527_05610	COG0514	ATP-dependent DNA helicase (RecQ)
BM527_05620	COG2356	endonuclease I
BM527_05635	COG0629	single-stranded DNA binding
BM527_05650	COG0714	Associated with various cellular activities
BM527_05675	COG2003	Belongs to the UPF0758 family
BM527_05780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM527_05790	COG5001	Diguanylate cyclase
BM527_05790	COG3300	MHYT domain
BM527_05810	COG0745	RESPONSE REGULATOR receiver
BM527_05810	COG3706	GGDEF domain
BM527_05840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BM527_05845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM527_05850	COG0564	pseudouridine synthase activity
BM527_05860	COG0612	Peptidase, M16
BM527_05865	COG2918	glutathione biosynthetic process
BM527_05885	COG2890	protein-(glutamine-N5) methyltransferase activity
BM527_05900	COG2719	SpoVR family
BM527_05905	COG2718	Belongs to the UPF0229 family
BM527_05910	COG2766	serine protein kinase
BM527_05920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BM527_05925	COG4771	TonB-dependent receptor
BM527_05950	COG0450	alkyl hydroperoxide reductase
BM527_05955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM527_05965	COG0584	glycerophosphoryl diester phosphodiesterase
BM527_05970	COG0346	lactoylglutathione lyase activity
BM527_05975	COG0346	lactoylglutathione lyase activity
BM527_05980	COG1278	Cold shock
BM527_05995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BM527_06000	COG4660	Part of a membrane complex involved in electron transport
BM527_06005	COG4659	FMN binding
BM527_06010	COG4658	electron transport chain
BM527_06015	COG4656	Part of a membrane complex involved in electron transport
BM527_06020	COG2878	Part of a membrane complex involved in electron transport
BM527_06025	COG4657	Part of a membrane complex involved in electron transport
BM527_06035	COG0534	Mate efflux family protein
BM527_06040	COG0556	nucleotide-excision repair
BM527_06055	COG0602	queuosine metabolic process
BM527_06065	COG0367	asparagine synthase
BM527_06085	COG3273	potassium ion transport
BM527_06085	COG0471	metal ion transport
BM527_06100	COG0529	Catalyzes the synthesis of activated sulfate
BM527_06105	COG0175	sulfate reduction
BM527_06110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM527_06115	COG2199	diguanylate cyclase activity
BM527_06115	COG2203	Gaf domain
BM527_06140	COG2304	oxidoreductase activity
BM527_06160	COG0714	Associated with various cellular activities
BM527_06175	COG1024	Enoyl-CoA hydratase
BM527_06175	COG1250	3-hydroxyacyl-CoA dehydrogenase
BM527_06190	COG1025	Belongs to the peptidase M16 family
BM527_06195	COG2062	phosphohistidine phosphatase, SixA
BM527_06205	COG4536	flavin adenine dinucleotide binding
BM527_06210	COG4137	Cytochrome C assembly protein
BM527_06215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BM527_06255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM527_06260	COG1132	(ABC) transporter
BM527_06270	COG0228	four-way junction DNA binding
BM527_06275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BM527_06280	COG0336	Belongs to the RNA methyltransferase TrmD family
BM527_06285	COG0335	large ribosomal subunit rRNA binding
BM527_06290	COG2860	membrane
BM527_06300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BM527_06305	COG1605	Chorismate mutase
BM527_06305	COG0287	Prephenate dehydrogenase
BM527_06310	COG0077	Prephenate dehydratase
BM527_06310	COG1605	Chorismate mutase
BM527_06315	COG0745	RESPONSE REGULATOR receiver
BM527_06320	COG0023	Translation Initiation Factor
BM527_06350	COG2205	protein histidine kinase activity
BM527_06360	COG2204	response regulator
BM527_06375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BM527_06380	COG0494	nUDIX hydrolase
BM527_06395	COG2255	four-way junction helicase activity
BM527_06400	COG0824	Thioesterase
BM527_06405	COG0811	peptide transport
BM527_06420	COG0823	Involved in the tonB-independent uptake of proteins
BM527_06425	COG2885	chlorophyll binding
BM527_06430	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BM527_06440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BM527_06455	COG4771	TonB-dependent receptor
BM527_06465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BM527_06475	COG2205	protein histidine kinase activity
BM527_06475	COG0784	Response regulator, receiver
BM527_06505	COG1451	nucleotide metabolic process
BM527_06510	COG0517	IMP dehydrogenase activity
BM527_06515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM527_06525	COG1309	transcriptional regulator
BM527_06530	COG4774	siderophore transport
BM527_06550	COG3706	GGDEF domain
BM527_06560	COG3008	intermembrane lipid transfer
BM527_06560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BM527_06565	COG2995	paraquat-inducible protein a
BM527_06575	COG0017	Asparaginyl-tRNA synthetase
BM527_06590	COG0189	ligase activity
BM527_06625	COG2226	methyltransferase
BM527_06635	COG3340	Belongs to the peptidase S51 family
BM527_06640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BM527_06645	COG4139	cobalamin transport
BM527_06650	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BM527_06655	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BM527_06660	COG2205	protein histidine kinase activity
BM527_06665	COG0745	RESPONSE REGULATOR receiver
BM527_06670	COG0569	domain protein
BM527_06675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BM527_06690	COG5265	(ABC) transporter
BM527_06695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BM527_06705	COG0745	RESPONSE REGULATOR receiver
BM527_06715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BM527_06740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM527_06750	COG2755	lipolytic protein G-D-S-L family
BM527_06755	COG4181	ATPase activity
BM527_06760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BM527_06765	COG1090	epimerase
BM527_06770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BM527_06775	COG0628	permease
BM527_06785	COG0745	RESPONSE REGULATOR receiver
BM527_06800	COG2350	Protein conserved in bacteria
BM527_06805	COG0159	tryptophan synthase activity
BM527_06815	COG0134	indole-3-glycerol-phosphate synthase activity
BM527_06815	COG0135	phosphoribosylanthranilate isomerase activity
BM527_06820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BM527_06830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BM527_06835	COG0613	PHP domain protein
BM527_06840	COG0009	L-threonylcarbamoyladenylate synthase
BM527_06850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BM527_06860	COG0656	L-ascorbic acid biosynthetic process
BM527_06865	COG0110	maltose O-acetyltransferase activity
BM527_06880	COG2733	membrane
BM527_06885	COG0500	methyltransferase
BM527_06890	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM527_06895	COG0497	DNA recombination
BM527_06900	COG0783	Belongs to the Dps family
BM527_06915	COG1454	alcohol dehydrogenase
BM527_06920	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_06930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BM527_06935	COG2610	gluconate transmembrane transporter activity
BM527_06955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM527_06955	COG0784	Response regulator, receiver
BM527_06955	COG2205	protein histidine kinase activity
BM527_06955	COG2198	Histidine kinase
BM527_06965	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BM527_06975	COG0484	heat shock protein binding
BM527_06980	COG3909	cytochrome
BM527_06985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BM527_07000	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BM527_07010	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BM527_07015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM527_07020	COG1858	cytochrome C peroxidase
BM527_07025	COG0840	transmembrane signaling receptor activity
BM527_07045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BM527_07050	COG0280	phosphate acetyltransferase
BM527_07050	COG0857	belongs to the CobB CobQ family
BM527_07060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BM527_07065	COG4535	Mg2 and Co2 transporter CorC
BM527_07075	COG1702	phosphate starvation-inducible protein PhoH
BM527_07085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM527_07125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM527_07165	COG1522	sequence-specific DNA binding
BM527_07170	COG1607	acyl-coa hydrolase
BM527_07175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM527_07185	COG1115	amino acid carrier protein
BM527_07190	COG0012	GTP binding
BM527_07205	COG1064	alcohol dehydrogenase
BM527_07220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BM527_07230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BM527_07240	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BM527_07250	COG2890	protein-(glutamine-N5) methyltransferase activity
BM527_07255	COG0784	Response regulator, receiver
BM527_07255	COG3437	response regulator, receiver
BM527_07265	COG3094	Invasion gene expression up-regulator, SirB
BM527_07280	COG0583	DNA-binding transcription factor activity
BM527_07290	COG2363	Small membrane protein
BM527_07315	COG0714	Associated with various cellular activities
BM527_07320	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BM527_07325	COG0033	Phosphoglucomutase
BM527_07330	COG0058	SHG alpha-glucan phosphorylase activity
BM527_07345	COG2988	succinylglutamate desuccinylase activity
BM527_07360	COG1506	peptidase
BM527_07365	COG5001	Diguanylate cyclase
BM527_07405	COG1301	dicarboxylic acid transport
BM527_07425	COG1393	Belongs to the ArsC family
BM527_07450	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BM527_07455	COG1846	Transcriptional regulator
BM527_07485	COG0402	S-adenosylhomocysteine deaminase activity
BM527_07510	COG1741	Belongs to the pirin family
BM527_07530	COG0583	DNA-binding transcription factor activity
BM527_07540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BM527_07545	COG3300	MHYT domain
BM527_07545	COG5001	Diguanylate cyclase
BM527_07570	COG2249	NAD(P)H dehydrogenase (quinone) activity
BM527_07590	COG1733	regulation of RNA biosynthetic process
BM527_07595	COG5002	protein histidine kinase activity
BM527_07595	COG5001	Diguanylate cyclase
BM527_07595	COG3447	MASE1 domain protein
BM527_07605	COG0402	S-adenosylhomocysteine deaminase activity
BM527_07610	COG2351	hydroxyisourate hydrolase activity
BM527_07625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM527_07635	COG1309	transcriptional regulator
BM527_07650	COG2252	PERMEase
BM527_07655	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BM527_07665	COG3706	GGDEF domain
BM527_07665	COG4251	negative regulation of phosphorylation
BM527_07665	COG5001	Diguanylate cyclase
BM527_07665	COG2203	Gaf domain
BM527_07670	COG2205	protein histidine kinase activity
BM527_07670	COG0784	Response regulator, receiver
BM527_07685	COG2233	PERMEase
BM527_07700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM527_07705	COG0730	response to heat
BM527_07715	COG0154	amidase activity
BM527_07760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BM527_07780	COG0072	phenylalanine-tRNA ligase activity
BM527_07780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM527_07815	COG1472	Belongs to the glycosyl hydrolase 3 family
BM527_07820	COG2096	Adenosyltransferase
BM527_07830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BM527_07840	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM527_07865	COG0708	Exodeoxyribonuclease III
BM527_07900	COG2814	Major facilitator Superfamily
BM527_07940	COG1024	Enoyl-CoA hydratase
BM527_07945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BM527_07950	COG1960	acyl-CoA dehydrogenase activity
BM527_07955	COG0789	Transcriptional regulator
BM527_07960	COG0183	Belongs to the thiolase family
BM527_07975	COG3447	MASE1 domain protein
BM527_07975	COG5002	protein histidine kinase activity
BM527_07975	COG5001	Diguanylate cyclase
BM527_07985	COG2925	Exonuclease
BM527_07990	COG1446	asparaginase
BM527_08030	COG1643	Atp-dependent helicase
BM527_08050	COG0604	alcohol dehydrogenase
BM527_08050	COG3321	synthase
BM527_08055	COG0328	RNA-DNA hybrid ribonuclease activity
BM527_08060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BM527_08075	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BM527_08080	COG1136	(ABC) transporter
BM527_08085	COG4591	ABC-type transport system involved in lipoprotein release permease component
BM527_08100	COG3724	N-succinylarginine dihydrolase activity
BM527_08105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BM527_08115	COG0746	molybdenum cofactor guanylyltransferase activity
BM527_08120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BM527_08125	COG0243	molybdopterin cofactor binding
BM527_08130	COG2153	protein acetylation
BM527_08140	COG5002	protein histidine kinase activity
BM527_08150	COG1530	ribonuclease E activity
BM527_08155	COG0564	pseudouridine synthase activity
BM527_08160	COG0546	phosphoglycolate phosphatase activity
BM527_08165	COG0424	maF-like protein
BM527_08170	COG1399	metal-binding, possibly nucleic acid-binding protein
BM527_08180	COG0416	fatty acid biosynthetic process
BM527_08185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BM527_08190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BM527_08200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BM527_08205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BM527_08210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BM527_08215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BM527_08230	COG0084	hydrolase, TatD family'
BM527_08240	COG0702	epimerase
BM527_08245	COG3706	GGDEF domain
BM527_08265	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_08270	COG0596	Alpha beta hydrolase
BM527_08280	COG0183	Belongs to the thiolase family
BM527_08285	COG1960	acyl-CoA dehydrogenase activity
BM527_08330	COG0668	transmembrane transport
BM527_08335	COG4771	TonB-dependent receptor
BM527_08355	COG3437	response regulator, receiver
BM527_08365	COG0195	Participates in both transcription termination and antitermination
BM527_08380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BM527_08400	COG3344	reverse transcriptase
BM527_08405	COG1187	pseudouridine synthase activity
BM527_08415	COG3153	acetyltransferase
BM527_08415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM527_08440	COG0450	alkyl hydroperoxide reductase
BM527_08485	COG1032	radical SAM domain protein
BM527_08500	COG4771	TonB-dependent receptor
BM527_08505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM527_08515	COG4134	Bacterial extracellular solute-binding protein
BM527_08525	COG4136	ATPase activity
BM527_08530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BM527_08545	COG4251	negative regulation of phosphorylation
BM527_08545	COG5001	Diguanylate cyclase
BM527_08545	COG2203	Gaf domain
BM527_08545	COG3706	GGDEF domain
BM527_08585	COG1131	(ABC) transporter
BM527_08600	COG1902	pentaerythritol trinitrate reductase activity
BM527_08610	COG2867	negative regulation of translational initiation
BM527_08615	COG2914	Belongs to the UPF0125 (RnfH) family
BM527_08625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM527_08630	COG4771	TonB-dependent receptor
BM527_08635	COG0457	Tetratricopeptide repeat
BM527_08650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BM527_08650	COG0574	Belongs to the PEP-utilizing enzyme family
BM527_08680	COG2850	peptidyl-arginine hydroxylation
BM527_08690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BM527_08695	COG2915	High frequency lysogenization protein hflD homolog
BM527_08700	COG0482	sulfurtransferase activity
BM527_08705	COG1187	pseudouridine synthase activity
BM527_08715	COG1278	Cold shock
BM527_08720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BM527_08725	COG0542	response to heat
BM527_08730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BM527_08735	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BM527_08740	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BM527_08745	COG0492	ferredoxin-NADP+ reductase activity
BM527_08750	COG3092	negative regulation of chromosome organization
BM527_08755	COG0616	signal peptide processing
BM527_08765	COG0778	Nitroreductase
BM527_08775	COG0252	asparaginase activity
BM527_08780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BM527_08785	COG0321	lipoyl(octanoyl) transferase activity
BM527_08790	COG2921	Belongs to the UPF0250 family
BM527_08795	COG1686	Belongs to the peptidase S11 family
BM527_08800	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM527_08805	COG0772	Belongs to the SEDS family
BM527_08810	COG0768	penicillin binding
BM527_08815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BM527_08820	COG0799	negative regulation of ribosome biogenesis
BM527_08825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BM527_08830	COG1466	dna polymerase III delta subunit
BM527_08835	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BM527_08840	COG0495	leucyl-tRNA aminoacylation
BM527_08850	COG1067	ATP-dependent peptidase activity
BM527_08855	COG0596	Alpha beta hydrolase
BM527_08860	COG3706	GGDEF domain
BM527_08870	COG1534	Rna-binding protein
BM527_08875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BM527_08880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM527_08885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BM527_08890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BM527_08895	COG0149	triose-phosphate isomerase activity
BM527_08900	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM527_08910	COG3300	MHYT domain
BM527_08910	COG5001	Diguanylate cyclase
BM527_08930	COG1803	Methylglyoxal synthase
BM527_08930	COG1597	lipid kinase activity
BM527_08940	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_08945	COG0561	phosphatase activity
BM527_08960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM527_08985	COG1185	polyribonucleotide nucleotidyltransferase activity
BM527_09150	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BM527_09155	COG1196	nuclear chromosome segregation
BM527_09165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BM527_09180	COG1132	(ABC) transporter
BM527_09185	COG1663	tetraacyldisaccharide 4'-kinase activity
BM527_09200	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_09220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BM527_09225	COG0435	Glutathione S-transferase
BM527_09230	COG1741	Belongs to the pirin family
BM527_09245	COG0372	Belongs to the citrate synthase family
BM527_09250	COG2009	succinate dehydrogenase
BM527_09255	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BM527_09260	COG1053	succinate dehydrogenase
BM527_09265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BM527_09270	COG0567	Dehydrogenase, E1 component
BM527_09275	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM527_09320	COG4667	esterase of the alpha-beta hydrolase superfamily
BM527_09345	COG0366	Alpha amylase catalytic
BM527_09370	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_09375	COG2267	carboxylic ester hydrolase activity
BM527_09380	COG0616	signal peptide processing
BM527_09395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BM527_09400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM527_09405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM527_09410	COG0386	Belongs to the glutathione peroxidase family
BM527_09415	COG2084	Dehydrogenase
BM527_09425	COG1960	acyl-CoA dehydrogenase activity
BM527_09430	COG1024	Enoyl-CoA hydratase
BM527_09435	COG2226	methyltransferase
BM527_09440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM527_09445	COG3083	sulfuric ester hydrolase activity
BM527_09450	COG3082	Protein of unknown function (DUF1414)
BM527_09455	COG3081	Nucleoid-associated protein
BM527_09465	COG1196	nuclear chromosome segregation
BM527_09465	COG0741	lytic transglycosylase activity
BM527_09465	COG0739	heme binding
BM527_09485	COG3275	phosphorelay sensor kinase activity
BM527_09490	COG3279	Response regulator of the LytR AlgR family
BM527_09495	COG0205	6-phosphofructokinase activity
BM527_09515	COG2205	protein histidine kinase activity
BM527_09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM527_09540	COG0513	Belongs to the DEAD box helicase family
BM527_09550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BM527_09555	COG0583	DNA-binding transcription factor activity
BM527_09575	COG1760	l-serine dehydratase
BM527_09580	COG0494	nUDIX hydrolase
BM527_09595	COG1322	Protein conserved in bacteria
BM527_09600	COG1404	Belongs to the peptidase S8 family
BM527_09605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BM527_09610	COG0022	dehydrogenase e1 component
BM527_09620	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BM527_09625	COG0515	serine threonine protein kinase
BM527_09630	COG1946	Acyl-CoA thioesterase
BM527_09640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BM527_09650	COG1956	GAF domain-containing protein
BM527_09665	COG0793	Belongs to the peptidase S41A family
BM527_09670	COG0733	neurotransmitter:sodium symporter activity
BM527_09680	COG0308	aminopeptidase N
BM527_09715	COG0167	dihydroorotate dehydrogenase activity
BM527_09740	COG3130	regulation of translation
BM527_09745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BM527_09755	COG0415	Belongs to the DNA photolyase family
BM527_09760	COG0415	Belongs to the DNA photolyase family
BM527_09765	COG0415	Belongs to the DNA photolyase family
BM527_09770	COG3046	protein related to deoxyribodipyrimidine photolyase
BM527_09795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BM527_09800	COG0589	response to stress
BM527_09810	COG0069	glutamate synthase activity
BM527_09825	COG2193	ferroxidase activity
BM527_09835	COG3278	Belongs to the heme-copper respiratory oxidase family
BM527_09850	COG2010	Cytochrome c
BM527_09875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM527_09880	COG0589	response to stress
BM527_09885	COG0037	tRNA processing
BM527_09890	COG1752	Esterase of the alpha-beta hydrolase superfamily
BM527_09910	COG1280	lysine exporter protein (LysE YggA)
BM527_09915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BM527_09920	COG2897	thiosulfate sulfurtransferase activity
BM527_09925	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BM527_09975	COG0322	excinuclease ABC activity
BM527_09980	COG2197	response regulator
BM527_09985	COG1741	Belongs to the pirin family
BM527_09990	COG0436	Aminotransferase
BM527_09995	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BM527_10000	COG3384	dioxygenase
BM527_10005	COG2259	Doxx family
BM527_10010	COG0583	DNA-binding transcription factor activity
BM527_10025	COG0670	Belongs to the BI1 family
BM527_10030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BM527_10045	COG2920	part of a sulfur-relay system
BM527_10075	COG4206	TonB-dependent receptor
BM527_10075	COG4206	TonB-dependent receptor
BM527_10090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BM527_10095	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BM527_10100	COG0531	amino acid
BM527_10100	COG1674	ftsk spoiiie
BM527_10110	COG0686	Belongs to the AlaDH PNT family
BM527_10115	COG0284	orotidine-5'-phosphate decarboxylase activity
BM527_10120	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BM527_10135	COG0776	regulation of translation
BM527_10140	COG0539	negative regulation of cytoplasmic translation
BM527_10145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BM527_10150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BM527_10155	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BM527_10165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BM527_10170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM527_10175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BM527_10180	COG0633	Ferredoxin
BM527_10185	COG4221	oxidoreductase activity
BM527_10215	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BM527_10220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BM527_10230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BM527_10240	COG4783	chaperone-mediated protein folding
BM527_10250	COG1393	Belongs to the ArsC family
BM527_10285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BM527_10320	COG0572	uridine kinase
BM527_10325	COG3769	mannosylglycerate metabolic process
BM527_10330	COG1215	transferase activity, transferring glycosyl groups
BM527_10345	COG0303	'Molybdopterin
BM527_10350	COG0534	Mate efflux family protein
BM527_10365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM527_10370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BM527_10405	COG3547	Transposase (IS116 IS110 IS902 family)
BM527_10440	COG0405	Gamma-glutamyltransferase
BM527_10445	COG1024	Enoyl-CoA hydratase
BM527_10470	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BM527_10490	COG1448	Aminotransferase
BM527_10500	COG1671	Belongs to the UPF0178 family
BM527_10505	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_10515	COG1960	acyl-CoA dehydrogenase activity
BM527_10520	COG2207	Transcriptional regulator
BM527_10520	COG0662	Cupin 2, conserved barrel domain protein
BM527_10535	COG1505	serine-type exopeptidase activity
BM527_10575	COG0596	Alpha beta hydrolase
BM527_10585	COG0716	FMN binding
BM527_10595	COG0735	belongs to the Fur family
BM527_10605	COG1984	allophanate hydrolase subunit 2
BM527_10610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BM527_10615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BM527_10620	COG2996	Protein conserved in bacteria
BM527_10625	COG1765	OsmC-like protein
BM527_10630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM527_10640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM527_10655	COG0436	Aminotransferase
BM527_10660	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BM527_10665	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BM527_10690	COG3012	SEC-C Motif Domain Protein
BM527_10700	COG0604	alcohol dehydrogenase
BM527_10710	COG1960	acyl-CoA dehydrogenase activity
BM527_10735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BM527_10740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BM527_10755	COG0314	molybdopterin synthase activity
BM527_10760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BM527_10765	COG0315	cyclic pyranopterin monophosphate synthase activity
BM527_10770	COG0521	Mo-molybdopterin cofactor biosynthetic process
BM527_10785	COG0840	transmembrane signaling receptor activity
BM527_10790	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BM527_10800	COG0300	oxidoreductase activity
BM527_10850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BM527_10860	COG3268	Saccharopine dehydrogenase
BM527_10865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM527_10890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BM527_10900	COG5006	permease, DMT superfamily
BM527_10910	COG2094	Belongs to the DNA glycosylase MPG family
BM527_10925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM527_10930	COG1074	ATP-dependent DNA helicase activity
BM527_10935	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BM527_11045	COG0701	Predicted permease
BM527_11090	COG0789	Transcriptional regulator
BM527_11100	COG1196	nuclear chromosome segregation
BM527_11115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM527_11120	COG2963	transposase activity
BM527_11125	COG2801	Transposase and inactivated derivatives
BM527_11170	COG1022	Amp-dependent synthetase and ligase
BM527_11195	COG0583	DNA-binding transcription factor activity
BM527_11210	COG0640	Transcriptional regulator
BM527_11220	COG0583	DNA-binding transcription factor activity
BM527_11225	COG3932	Exopolysaccharide synthesis, ExoD
BM527_11230	COG2204	response regulator
BM527_11240	COG4251	negative regulation of phosphorylation
BM527_11245	COG0784	Response regulator, receiver
BM527_11250	COG5002	protein histidine kinase activity
BM527_11250	COG2198	Histidine kinase
BM527_11250	COG0784	Response regulator, receiver
BM527_11305	COG3139	Protein of unknown function (DUF1315)
BM527_11315	COG1115	amino acid carrier protein
BM527_11320	COG2866	Carboxypeptidase
BM527_11340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BM527_11350	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BM527_11355	COG1640	4-alpha-glucanotransferase
BM527_11370	COG0800	Aldolase
BM527_11380	COG0129	dihydroxy-acid dehydratase activity
BM527_11390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BM527_11395	COG1737	Transcriptional regulator
BM527_11400	COG0469	pyruvate kinase activity
BM527_11410	COG2823	Periplasmic or secreted lipoprotein
BM527_11455	COG2356	endonuclease I
BM527_11465	COG0840	transmembrane signaling receptor activity
BM527_11480	COG0583	DNA-binding transcription factor activity
BM527_11490	COG1979	alcohol dehydrogenase
BM527_11495	COG1902	pentaerythritol trinitrate reductase activity
BM527_11500	COG5001	Diguanylate cyclase
BM527_11515	COG0784	Response regulator, receiver
BM527_11515	COG3437	response regulator, receiver
BM527_11520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM527_11520	COG4191	Histidine kinase
BM527_11535	COG0471	metal ion transport
BM527_11550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM527_11550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BM527_11555	COG2226	methyltransferase
BM527_11565	COG1388	LysM domain
BM527_11565	COG0741	lytic transglycosylase activity
BM527_11585	COG0215	cysteine-tRNA ligase activity
BM527_11590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BM527_11595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM527_11600	COG1785	Belongs to the alkaline phosphatase family
BM527_11605	COG1785	Belongs to the alkaline phosphatase family
BM527_11615	COG1585	Membrane protein implicated in regulation of membrane protease activity
BM527_11620	COG2268	Band 7 protein
BM527_11630	COG1733	regulation of RNA biosynthetic process
BM527_11635	COG0604	alcohol dehydrogenase
BM527_11640	COG0604	alcohol dehydrogenase
BM527_11645	COG0583	DNA-binding transcription factor activity
BM527_11670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BM527_11675	COG1286	toxin biosynthetic process
BM527_11680	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BM527_11685	COG0285	dihydrofolate synthase activity
BM527_11715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM527_11745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BM527_11745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM527_11780	COG0604	alcohol dehydrogenase
BM527_11785	COG1119	ATPase activity
BM527_11795	COG2031	fatty acid transporter
BM527_11810	COG0612	Peptidase, M16
BM527_11825	COG3101	peptidyl-lysine hydroxylation
BM527_11850	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM527_11850	COG1902	pentaerythritol trinitrate reductase activity
BM527_11875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BM527_11885	COG4399	Belongs to the UPF0754 family
BM527_11915	COG2186	Transcriptional regulator
BM527_11925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BM527_11930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BM527_11940	COG2983	Belongs to the UPF0260 family
BM527_11945	COG0179	Fumarylacetoacetate (FAA) hydrolase
BM527_11960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BM527_11965	COG0318	PFAM AMP-dependent synthetase and ligase
BM527_11970	COG2267	carboxylic ester hydrolase activity
BM527_11990	COG1199	ATP-dependent helicase activity
BM527_12065	COG4771	TonB-dependent receptor
BM527_12080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BM527_12085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BM527_12090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM527_12095	COG0131	Imidazoleglycerol-phosphate dehydratase
BM527_12095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BM527_12100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BM527_12115	COG0140	phosphoribosyl-ATP diphosphatase activity
BM527_12115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BM527_12125	COG2116	formate transmembrane transporter activity
BM527_12135	COG0612	Peptidase, M16
BM527_12175	COG0326	Molecular chaperone. Has ATPase activity
BM527_12180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BM527_12190	COG5001	Diguanylate cyclase
BM527_12215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BM527_12220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BM527_12230	COG3220	belongs to the UPF0276 family
BM527_12265	COG1183	phosphatidylcholine synthase activity
BM527_12285	COG0277	FAD linked oxidase domain protein
BM527_12290	COG0542	response to heat
BM527_12300	COG0564	pseudouridine synthase activity
BM527_12315	COG1595	DNA-templated transcription, initiation
BM527_12330	COG4221	oxidoreductase activity
BM527_12345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BM527_12355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BM527_12365	COG0142	geranyltranstransferase activity
BM527_12375	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BM527_12380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BM527_12390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BM527_12405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM527_12405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BM527_12420	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BM527_12425	COG0488	(ABC) transporter
BM527_12435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BM527_12445	COG0560	Phosphoserine phosphatase
BM527_12455	COG0084	hydrolase, TatD family'
BM527_12470	COG0571	ribonuclease III activity
BM527_12475	COG0681	Belongs to the peptidase S26 family
BM527_12500	COG1595	DNA-templated transcription, initiation
BM527_12505	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BM527_12520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BM527_12600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BM527_12605	COG1047	Peptidyl-prolyl cis-trans
BM527_12615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BM527_12620	COG0196	riboflavin kinase activity
BM527_12625	COG0728	peptidoglycan biosynthetic process
BM527_12630	COG0268	Binds directly to 16S ribosomal RNA
BM527_12645	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_12665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM527_12675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BM527_12705	COG0776	regulation of translation
BM527_12710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM527_12715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BM527_12720	COG0740	serine-type endopeptidase activity
BM527_12725	COG0544	peptidyl-prolyl cis-trans isomerase activity
BM527_12745	COG1720	tRNA m6t6A37 methyltransferase activity
BM527_12755	COG1234	tRNA 3'-trailer cleavage
BM527_12765	COG0123	including yeast histone deacetylase and acetoin utilization protein
BM527_12780	COG0516	GMP reductase activity
BM527_12780	COG0517	IMP dehydrogenase activity
BM527_12785	COG1570	exodeoxyribonuclease VII activity
BM527_12800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BM527_12805	COG2976	Protein conserved in bacteria
BM527_12820	COG1426	Protein conserved in bacteria
BM527_12830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BM527_12840	COG2166	iron-sulfur cluster assembly
BM527_12855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BM527_12860	COG0719	Fe-S assembly protein
BM527_12865	COG0396	ATPase activity
BM527_12870	COG0719	Fe-S assembly protein
BM527_12875	COG1104	cysteine desulfurase activity
BM527_12890	COG2072	flavoprotein involved in K transport
BM527_12895	COG1522	sequence-specific DNA binding
BM527_12910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM527_12915	COG1045	serine acetyltransferase
BM527_12920	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BM527_12925	COG0483	inositol monophosphate 1-phosphatase activity
BM527_12930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM527_12935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BM527_12940	COG1862	Preprotein translocase
BM527_12945	COG0343	queuine tRNA-ribosyltransferase activity
BM527_12965	COG1842	Phage shock protein A
BM527_12970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BM527_12990	COG0754	glutathionylspermidine amidase activity
BM527_13020	COG2066	Belongs to the glutaminase family
BM527_13025	COG1785	Belongs to the alkaline phosphatase family
BM527_13100	COG3436	PFAM IS66 Orf2 family protein
BM527_13160	COG0438	transferase activity, transferring glycosyl groups
BM527_13175	COG0367	asparagine synthase
BM527_13185	COG0438	transferase activity, transferring glycosyl groups
BM527_13225	COG1696	Membrane protein involved in D-alanine export
BM527_13275	COG0489	protein tyrosine kinase activity
BM527_13285	COG3409	Peptidoglycan-binding domain 1 protein
BM527_13285	COG3267	Type II secretory pathway component ExeA
BM527_13290	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BM527_13290	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BM527_13315	COG1560	Kdo2-lipid A biosynthetic process
BM527_13330	COG1960	acyl-CoA dehydrogenase activity
BM527_13350	COG1435	thymidine kinase activity
BM527_13355	COG1609	Transcriptional regulator
BM527_13360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BM527_13380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM527_13415	COG1012	belongs to the aldehyde dehydrogenase family
BM527_13435	COG3706	GGDEF domain
BM527_13445	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BM527_13475	COG1960	acyl-CoA dehydrogenase activity
BM527_13480	COG3706	GGDEF domain
BM527_13535	COG2080	2 iron, 2 sulfur cluster binding
BM527_13540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BM527_13545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BM527_13580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BM527_13585	COG4172	Belongs to the ABC transporter superfamily
BM527_13590	COG1028	Short-chain dehydrogenase reductase Sdr
BM527_13600	COG4221	oxidoreductase activity
BM527_13605	COG0693	protein deglycase activity
BM527_13610	COG1295	ribonuclease BN
BM527_13650	COG4681	YaeQ
BM527_13715	COG0514	ATP-dependent DNA helicase (RecQ)
BM527_13745	COG4251	negative regulation of phosphorylation
BM527_13750	COG2133	pyrroloquinoline quinone binding
BM527_13810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BM527_13850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BM527_13860	COG2971	BadF BadG BcrA BcrD
BM527_13885	COG0583	DNA-binding transcription factor activity
BM527_13900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM527_13905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BM527_13910	COG0006	proline dipeptidase activity
BM527_13925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM527_13940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BM527_13945	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BM527_13950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BM527_13970	COG3313	Fe-S protein
BM527_13995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM527_14000	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM527_14005	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BM527_14010	COG2186	Transcriptional regulator
BM527_14025	COG3577	Aspartyl protease
BM527_14040	COG1459	type II secretion system
BM527_14045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BM527_14050	COG0237	dephospho-CoA kinase activity
BM527_14055	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BM527_14065	COG3608	succinylglutamate desuccinylase aspartoacylase
BM527_14070	COG0840	transmembrane signaling receptor activity
BM527_14075	COG4566	intracellular signal transduction
BM527_14080	COG1192	Involved in chromosome partitioning
BM527_14090	COG0643	Histidine kinase
BM527_14090	COG2198	Histidine kinase
BM527_14095	COG0745	RESPONSE REGULATOR receiver
BM527_14100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BM527_14110	COG2201	protein-glutamate methylesterase activity
BM527_14115	COG0835	chemotaxis
BM527_14120	COG0840	transmembrane signaling receptor activity
BM527_14125	COG0494	nUDIX hydrolase
BM527_14135	COG0739	heme binding
BM527_14140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BM527_14145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BM527_14150	COG0849	cell division
BM527_14155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BM527_14160	COG1181	Belongs to the D-alanine--D-alanine ligase family
BM527_14165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BM527_14175	COG0772	Belongs to the SEDS family
BM527_14180	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BM527_14190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BM527_14195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BM527_14200	COG0768	penicillin binding
BM527_14205	COG3116	cell division
BM527_14215	COG2001	Belongs to the MraZ family
BM527_14235	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BM527_14260	COG0678	peroxiredoxin activity
BM527_14260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BM527_14275	COG3706	GGDEF domain
BM527_14285	COG2204	response regulator
BM527_14290	COG2205	protein histidine kinase activity
BM527_14290	COG0784	Response regulator, receiver
BM527_14310	COG0668	transmembrane transport
BM527_14315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BM527_14320	COG0189	ligase activity
BM527_14325	COG1678	Uncharacterized ACR, COG1678
BM527_14330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BM527_14355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BM527_14360	COG0762	integral membrane protein
BM527_14370	COG0446	pyridine nucleotide-disulphide oxidoreductase
BM527_14370	COG1902	pentaerythritol trinitrate reductase activity
BM527_14385	COG0625	glutathione transferase activity
BM527_14395	COG1764	response to oxidative stress
BM527_14400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BM527_14405	COG2814	Major facilitator Superfamily
BM527_14415	COG1629	transport
BM527_14415	COG4774	siderophore transport
BM527_14425	COG0724	RNA recognition motif
BM527_14445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BM527_14450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BM527_14470	COG0583	DNA-binding transcription factor activity
BM527_14490	COG0640	Transcriptional regulator
BM527_14500	COG0431	NADPH-dependent FMN reductase
BM527_14505	COG0798	PFAM Bile acid sodium symporter
BM527_14510	COG2201	protein-glutamate methylesterase activity
BM527_14515	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BM527_14525	COG3850	Histidine kinase
BM527_14525	COG5002	protein histidine kinase activity
BM527_14540	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BM527_14565	COG1748	Saccharopine dehydrogenase
BM527_14580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BM527_14585	COG3107	peptidoglycan biosynthetic process
BM527_14590	COG0792	nuclease activity
BM527_14600	COG2823	Periplasmic or secreted lipoprotein
BM527_14605	COG0477	Major facilitator Superfamily
BM527_14620	COG4585	Histidine kinase
BM527_14625	COG2197	response regulator
BM527_14650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BM527_14655	COG0372	Belongs to the citrate synthase family
BM527_14660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BM527_14665	COG2828	Protein conserved in bacteria
BM527_14670	COG2203	Gaf domain
BM527_14670	COG2199	diguanylate cyclase activity
BM527_14690	COG5002	protein histidine kinase activity
BM527_14690	COG0784	Response regulator, receiver
BM527_14690	COG2198	Histidine kinase
BM527_14700	COG0070	glutamate synthase
BM527_14700	COG0067	glutamate synthase
BM527_14700	COG0069	glutamate synthase activity
BM527_14705	COG0493	'glutamate synthase
BM527_14725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BM527_14730	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BM527_14735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BM527_14755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BM527_14760	COG5507	3-demethylubiquinone-9 3-methyltransferase
BM527_14780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BM527_14785	COG0741	lytic transglycosylase activity
BM527_14785	COG0739	heme binding
BM527_14785	COG1196	nuclear chromosome segregation
BM527_14790	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BM527_14795	COG0738	Major facilitator superfamily
BM527_14805	COG1902	pentaerythritol trinitrate reductase activity
BM527_14825	COG0625	glutathione transferase activity
BM527_14845	COG2894	cell division
BM527_14850	COG0850	regulation of cytokinetic process
BM527_14890	COG1914	H( )-stimulated, divalent metal cation uptake system
BM527_14910	COG0174	glutamine synthetase
BM527_14920	COG3852	Histidine kinase
BM527_14925	COG2204	response regulator
BM527_14930	COG3437	response regulator, receiver
BM527_14935	COG0204	Acyl-transferase
BM527_14960	COG0525	valine-tRNA ligase activity
BM527_14965	COG2927	DNA polymerase III (CHI subunit)
BM527_14970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM527_14975	COG0795	lipopolysaccharide-transporting ATPase activity
BM527_14980	COG0795	lipopolysaccharide-transporting ATPase activity
BM527_15050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BM527_15090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BM527_15115	COG0210	DNA helicase
BM527_15145	COG4948	Mandelate Racemase Muconate Lactonizing
BM527_15230	COG0673	inositol 2-dehydrogenase activity
BM527_15235	COG2198	Histidine kinase
BM527_15235	COG0784	Response regulator, receiver
BM527_15235	COG2205	protein histidine kinase activity
BM527_15235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BM527_15240	COG0628	permease
BM527_15290	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BM527_15315	COG3706	GGDEF domain
BM527_15360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BM527_15370	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BM527_15410	COG2205	protein histidine kinase activity
BM527_15420	COG0348	domain, Protein
BM527_15420	COG3901	Regulator of nitric oxide reductase transcription
BM527_15430	COG2197	response regulator
BM527_15455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BM527_15460	COG1304	FMN binding
BM527_15465	COG0277	FAD linked oxidase domain protein
BM527_15470	COG2197	response regulator
BM527_15485	COG0513	Belongs to the DEAD box helicase family
BM527_15490	COG5001	Diguanylate cyclase
BM527_15505	COG3264	Mechanosensitive ion channel
BM527_15505	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BM527_15550	COG0730	response to heat
BM527_15555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BM527_15570	COG4191	Histidine kinase
BM527_15580	COG0417	DNA replication proofreading
BM527_15590	COG0318	PFAM AMP-dependent synthetase and ligase
BM527_15650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM527_15660	COG1573	uracil-dna glycosylase
BM527_15665	COG3300	MHYT domain
BM527_15665	COG5001	Diguanylate cyclase
BM527_15685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM527_15705	COG1983	PspC domain protein
BM527_15710	COG1842	Phage shock protein A
BM527_15720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM527_15735	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BM527_15745	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BM527_15750	COG0204	Acyl-transferase
BM527_15755	COG0204	Acyl-transferase
BM527_15760	COG0668	transmembrane transport
BM527_15775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BM527_15780	COG0733	neurotransmitter:sodium symporter activity
BM527_15795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BM527_15810	COG0716	FMN binding
BM527_15820	COG0848	biopolymer transport protein
BM527_15830	COG0457	Tetratricopeptide repeat
BM527_15835	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BM527_15860	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BM527_15865	COG0702	epimerase
BM527_15880	COG5002	protein histidine kinase activity
BM527_15880	COG5001	Diguanylate cyclase
BM527_15890	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BM527_15900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM527_15910	COG0583	DNA-binding transcription factor activity
BM527_15915	COG0121	glutamine amidotransferase
BM527_15925	COG4682	membrane
BM527_15945	COG1953	Uracil, thiamine, allantoin
BM527_15950	COG4771	TonB-dependent receptor
BM527_15960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BM527_15965	COG0778	Nitroreductase
BM527_15970	COG0596	Alpha beta hydrolase
BM527_15975	COG0251	oxidation-reduction process
BM527_15980	COG1335	isochorismatase
BM527_15985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM527_15990	COG1309	transcriptional regulator
BM527_16005	COG4628	conserved protein (DUF2132)
BM527_16015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BM527_16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BM527_16045	COG1477	protein flavinylation
BM527_16050	COG2871	sodium ion transport
BM527_16055	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM527_16060	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM527_16065	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM527_16070	COG1805	sodium ion transport
BM527_16075	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BM527_16080	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BM527_16085	COG0545	Peptidyl-prolyl cis-trans isomerase
BM527_16090	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BM527_16105	COG0039	L-malate dehydrogenase activity
BM527_16110	COG1438	arginine binding
BM527_16135	COG0572	uridine kinase
BM527_16140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BM527_16155	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BM527_16165	COG4251	negative regulation of phosphorylation
BM527_16165	COG2203	Gaf domain
BM527_16165	COG3706	GGDEF domain
BM527_16165	COG5001	Diguanylate cyclase
BM527_16175	COG0517	IMP dehydrogenase activity
BM527_16175	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BM527_16180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM527_16190	COG2205	protein histidine kinase activity
BM527_16190	COG0784	Response regulator, receiver
BM527_16200	COG0189	ligase activity
BM527_16210	COG4067	protein conserved in archaea
BM527_16210	COG0189	ligase activity
BM527_16235	COG1283	sodium-dependent phosphate transmembrane transporter activity
BM527_16240	COG0667	Aldo Keto reductase
BM527_16265	COG0515	serine threonine protein kinase
BM527_16270	COG4585	Histidine kinase
BM527_16345	COG0583	DNA-binding transcription factor activity
BM527_16375	COG0438	transferase activity, transferring glycosyl groups
BM527_16375	COG1216	Glycosyl transferase, family 2
BM527_16385	COG1091	dTDP-4-dehydrorhamnose reductase activity
BM527_16410	COG0463	Glycosyl transferase, family 2
BM527_16425	COG1858	cytochrome C peroxidase
BM527_16475	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BM527_16480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BM527_16505	COG0463	Glycosyl transferase, family 2
BM527_16525	COG0438	transferase activity, transferring glycosyl groups
BM527_16550	COG1450	Type ii and iii secretion system protein
BM527_16580	COG2165	general secretion pathway protein
BM527_16625	COG1216	Glycosyl transferase, family 2
BM527_16625	COG0438	transferase activity, transferring glycosyl groups
BM527_16645	COG3754	Rhamnan synthesis protein F
BM527_16700	COG0202	RNA polymerase activity
BM527_16725	COG0201	protein transport
BM527_16745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BM527_16795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BM527_16800	COG0557	exoribonuclease II activity
BM527_16820	COG4771	TonB-dependent receptor
BM527_16835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BM527_16855	COG2234	aminopeptidase activity
BM527_16865	COG4251	negative regulation of phosphorylation
BM527_16875	COG1271	oxidase subunit
BM527_16880	COG1294	oxidase, subunit
BM527_16885	COG1522	sequence-specific DNA binding
BM527_16895	COG1278	Cold shock
BM527_16900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM527_16920	COG0339	signal peptide processing
BM527_16925	COG2201	protein-glutamate methylesterase activity
BM527_16935	COG3852	Histidine kinase
BM527_16945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BM527_16950	COG0243	molybdopterin cofactor binding
BM527_17000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BM527_17010	COG2197	response regulator
BM527_17040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BM527_17055	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BM527_17060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BM527_17075	COG0281	malic enzyme
BM527_17085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BM527_17115	COG0456	acetyltransferase
BM527_17125	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM527_17130	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BM527_17135	COG2177	Part of the ABC transporter FtsEX involved in
BM527_17140	COG2884	Cell division ATP-binding protein ftsE
BM527_17145	COG0552	protein localization to endoplasmic reticulum
BM527_17150	COG0742	ribosomal rna small subunit methyltransferase
BM527_17160	COG2095	MarC family integral membrane protein
BM527_17180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BM527_17195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BM527_17210	COG0076	glutamate decarboxylase activity
BM527_17225	COG0842	Transport permease protein
BM527_17230	COG1131	(ABC) transporter
BM527_17235	COG0745	RESPONSE REGULATOR receiver
BM527_17240	COG2205	protein histidine kinase activity
BM527_17245	COG4774	siderophore transport
BM527_17275	COG1253	flavin adenine dinucleotide binding
BM527_17280	COG0701	Predicted permease
BM527_17285	COG1966	Carbon starvation protein
BM527_17315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BM527_17320	COG0049	tRNA binding
BM527_17325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BM527_17330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BM527_17335	COG0085	RNA polymerase activity
BM527_17340	COG0222	ribosome binding
BM527_17345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BM527_17350	COG0081	regulation of translation
BM527_17355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BM527_17365	COG3706	GGDEF domain
BM527_17370	COG0250	Participates in transcription elongation, termination and antitermination
BM527_17375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BM527_17385	COG1132	(ABC) transporter
BM527_17390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BM527_17395	COG3590	peptidase
BM527_17410	COG0513	Belongs to the DEAD box helicase family
BM527_17420	COG0418	dihydroorotase activity
BM527_17425	COG3040	lipid binding
BM527_17430	COG4989	oxidoreductase activity
BM527_17435	COG0346	lactoylglutathione lyase activity
BM527_17440	COG0668	transmembrane transport
BM527_17460	COG0302	gtp cyclohydrolase
BM527_17470	COG2957	Belongs to the agmatine deiminase family
BM527_17475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BM527_17490	COG1201	RNA secondary structure unwinding
BM527_17510	COG1793	dna ligase
BM527_17515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BM527_17520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BM527_17525	COG1940	carbohydrate kinase activity
BM527_17530	COG1410	methionine synthase
BM527_17530	COG0646	methionine synthase
BM527_17535	COG0625	glutathione transferase activity
BM527_17540	COG0625	glutathione transferase activity
BM527_17550	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BM527_17565	COG1012	belongs to the aldehyde dehydrogenase family
BM527_17570	COG0028	Belongs to the TPP enzyme family
BM527_17580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BM527_17585	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BM527_17590	COG0330	HflC and HflK could
BM527_17595	COG0330	HflC and HflK could
BM527_17600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BM527_17605	COG1923	regulation of RNA biosynthetic process
BM527_17610	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BM527_17625	COG0802	atpase or kinase
BM527_17630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BM527_17630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BM527_17635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BM527_17645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BM527_17660	COG0735	belongs to the Fur family
BM527_17670	COG0432	Pfam Uncharacterised protein family UPF0047
BM527_17680	COG0305	Participates in initiation and elongation during chromosome replication
BM527_17705	COG2258	MOSC domain
BM527_17715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BM527_17735	COG0784	Response regulator, receiver
BM527_17735	COG2205	protein histidine kinase activity
BM527_17735	COG2198	Histidine kinase
BM527_17745	COG1136	(ABC) transporter
BM527_17755	COG0840	transmembrane signaling receptor activity
BM527_17760	COG5002	protein histidine kinase activity
BM527_17765	COG5278	phosphoserine phosphatase activity
BM527_17765	COG0840	transmembrane signaling receptor activity
BM527_17780	COG2855	membrane
BM527_17785	COG2175	clavaminate synthase activity
BM527_17790	COG0656	L-ascorbic acid biosynthetic process
BM527_17810	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BM527_17815	COG4771	TonB-dependent receptor
BM527_17860	COG3706	GGDEF domain
BM527_17865	COG1472	Belongs to the glycosyl hydrolase 3 family
BM527_17875	COG2723	6-phospho-beta-galactosidase activity
BM527_17880	COG1609	Transcriptional regulator
BM527_17885	COG0477	Major facilitator Superfamily
BM527_17885	COG2814	Major facilitator Superfamily
BM527_17890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BM527_17895	COG4988	ABC transporter
BM527_17900	COG4890	Cyd operon protein YbgT
BM527_17905	COG1294	oxidase, subunit
BM527_17945	COG4319	ketosteroid isomerase
BM527_17950	COG1335	isochorismatase
BM527_17955	COG2863	cytochrome
BM527_17960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BM527_17965	COG1741	Belongs to the pirin family
BM527_17975	COG4771	TonB-dependent receptor
BM527_17990	COG1469	GTP cyclohydrolase I activity
BM527_18015	COG3706	GGDEF domain
BM527_18025	COG2375	cellular response to nickel ion
BM527_18030	COG3237	CsbD-like
BM527_18045	COG0508	dehydrogenase complex catalyzes the overall conversion of
BM527_18045	COG0596	Alpha beta hydrolase
BM527_18070	COG3038	cytochrome b561
BM527_18080	COG1252	NADH dehydrogenase
BM527_18085	COG4206	TonB-dependent receptor
BM527_18095	COG0583	DNA-binding transcription factor activity
BM527_18105	COG2130	NADP-dependent
BM527_18110	COG4251	negative regulation of phosphorylation
BM527_18110	COG3706	GGDEF domain
BM527_18110	COG2203	Gaf domain
BM527_18110	COG5001	Diguanylate cyclase
BM527_18115	COG2205	protein histidine kinase activity
BM527_18115	COG0784	Response regulator, receiver
BM527_18125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BM527_18130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BM527_18135	COG1349	DNA-binding transcription factor activity
BM527_18140	COG0673	inositol 2-dehydrogenase activity
BM527_18155	COG0697	spore germination
BM527_18160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BM527_18165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BM527_18170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BM527_18175	COG1166	arginine decarboxylase activity
BM527_18185	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BM527_18190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BM527_18195	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BM527_18210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BM527_18235	COG1324	tolerance protein
BM527_18240	COG4232	protein-disulfide reductase activity
BM527_18245	COG0739	heme binding
BM527_18250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BM527_18255	COG0511	ligase activity, forming carbon-carbon bonds
BM527_18260	COG0439	Biotin carboxylase
BM527_18280	COG2176	DNA-directed DNA polymerase activity
BM527_18300	COG0154	amidase activity
BM527_18315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BM527_18320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BM527_18335	COG0151	Belongs to the GarS family
BM527_18345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BM527_18350	COG3954	Phosphoribulokinase
BM527_18360	COG0745	RESPONSE REGULATOR receiver
BM527_18375	COG1501	Belongs to the glycosyl hydrolase 31 family
BM527_18385	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BM527_18395	COG3031	protein transport across the cell outer membrane
BM527_18405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BM527_18410	COG1459	type II secretion system
BM527_18415	COG2165	general secretion pathway protein
BM527_18420	COG2165	general secretion pathway protein
BM527_18430	COG4795	General secretion pathway protein
BM527_18435	COG3156	type II secretion system protein K
BM527_18445	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BM527_18465	COG1012	belongs to the aldehyde dehydrogenase family
BM527_18475	COG1011	Hydrolase
BM527_18480	COG0494	nUDIX hydrolase
BM527_18485	COG1218	3'(2'),5'-bisphosphate nucleotidase
BM527_18500	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BM527_18510	COG3089	Belongs to the UPF0270 family
BM527_18515	COG0429	hydrolase of the alpha beta-hydrolase fold
BM527_18525	COG0488	(ABC) transporter
BM527_18550	COG0545	Peptidyl-prolyl cis-trans isomerase
BM527_18560	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BM527_18565	COG2183	response to ionizing radiation
BM527_18585	COG0596	Alpha beta hydrolase
BM527_18590	COG1040	competence protein
BM527_18610	COG1794	racemase activity, acting on amino acids and derivatives
BM527_18625	COG0534	Mate efflux family protein
BM527_18630	COG0726	polysaccharide deacetylase
BM527_18630	COG1649	PFAM Uncharacterised BCR, COG1649
BM527_18640	COG1999	signal sequence binding
BM527_18645	COG0109	protoheme IX farnesyltransferase activity
BM527_18650	COG1612	heme a metabolic process
BM527_18675	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BM527_18680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BM527_18685	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BM527_18695	COG3706	GGDEF domain
BM527_18710	COG0129	dihydroxy-acid dehydratase activity
BM527_18720	COG0606	chelatase, subunit chli
BM527_18725	COG0583	DNA-binding transcription factor activity
BM527_18735	COG2814	Major facilitator Superfamily
BM527_18745	COG0729	surface antigen
BM527_18750	COG2911	Protein conserved in bacteria
BM527_18775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BM527_18785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BM527_18805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BM527_18830	COG1228	amidohydrolase
BM527_18850	COG0425	Belongs to the sulfur carrier protein TusA family
BM527_18865	COG1561	YicC-like family, N-terminal region
BM527_18890	COG2211	Major facilitator Superfamily
BM527_18895	COG1609	Transcriptional regulator
BM527_18910	COG2770	Histidine kinase
BM527_18910	COG3437	response regulator, receiver
BM527_18935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BM527_18955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BM527_18960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BM527_18980	COG1475	DNA binding
BM527_18985	COG1192	Involved in chromosome partitioning
BM527_19010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BM527_19015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BM527_19025	COG0706	membrane insertase activity
BM527_19030	COG0594	ribonuclease P activity
BM527_19035	COG0230	Belongs to the bacterial ribosomal protein bL34 family