locus-tag	class	description
AOR13_1004	COG2826	transposase and inactivated derivatives, IS30 family
AOR13_1009	COG1073	alpha beta
AOR13_101	COG0668	transmembrane transport
AOR13_1010	COG2207	Transcriptional regulator
AOR13_1017	COG3101	peptidyl-lysine hydroxylation
AOR13_102	COG0204	Acyl-transferase
AOR13_1024	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOR13_1024	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOR13_103	COG0204	Acyl-transferase
AOR13_1030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOR13_1034	COG0101	tRNA pseudouridine synthase activity
AOR13_1036	COG0285	dihydrofolate synthase activity
AOR13_1037	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AOR13_1038	COG1286	toxin biosynthetic process
AOR13_1039	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOR13_104	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AOR13_1042	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AOR13_1044	COG2080	2 iron, 2 sulfur cluster binding
AOR13_1045	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AOR13_1046	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOR13_1047	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOR13_1051	COG2268	Band 7 protein
AOR13_1054	COG1785	Belongs to the alkaline phosphatase family
AOR13_1055	COG1785	Belongs to the alkaline phosphatase family
AOR13_1057	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOR13_1061	COG0741	lytic transglycosylase activity
AOR13_1061	COG1388	LysM domain
AOR13_1062	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_1063	COG2226	methyltransferase
AOR13_1064	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_1064	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_1065	COG0489	protein tyrosine kinase activity
AOR13_1067	COG0471	metal ion transport
AOR13_1071	COG0778	Nitroreductase
AOR13_1075	COG0330	HflC and HflK could
AOR13_1078	COG0753	catalase activity
AOR13_1080	COG0840	transmembrane signaling receptor activity
AOR13_1086	COG0738	Major facilitator superfamily
AOR13_1087	COG1957	nucleoside hydrolase
AOR13_1093	COG5002	protein histidine kinase activity
AOR13_1093	COG3850	Histidine kinase
AOR13_1094	COG0745	RESPONSE REGULATOR receiver
AOR13_1096	COG3706	GGDEF domain
AOR13_110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOR13_1100	COG1764	response to oxidative stress
AOR13_1101	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOR13_1103	COG0746	molybdenum cofactor guanylyltransferase activity
AOR13_1107	COG3300	MHYT domain
AOR13_1107	COG5001	Diguanylate cyclase
AOR13_1110	COG0673	inositol 2-dehydrogenase activity
AOR13_1111	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_1112	COG1609	Transcriptional regulator
AOR13_1117	COG1024	Enoyl-CoA hydratase
AOR13_1119	COG2356	endonuclease I
AOR13_112	COG1842	Phage shock protein A
AOR13_1123	COG4677	pectinesterase activity
AOR13_1125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AOR13_1127	COG2755	lipolytic protein G-D-S-L family
AOR13_1128	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_1129	COG0246	Mannitol dehydrogenase
AOR13_1130	COG1904	glucuronate isomerase
AOR13_1131	COG2721	sulfolactate sulfo-lyase activity
AOR13_1136	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AOR13_1137	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_1140	COG3665	Urea carboxylase-associated protein
AOR13_1145	COG0745	RESPONSE REGULATOR receiver
AOR13_1146	COG2205	protein histidine kinase activity
AOR13_1154	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOR13_1156	COG0469	pyruvate kinase activity
AOR13_1157	COG1737	Transcriptional regulator
AOR13_1158	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOR13_1160	COG0129	dihydroxy-acid dehydratase activity
AOR13_1162	COG0800	Aldolase
AOR13_1163	COG0676	glucose-6-phosphate 1-epimerase activity
AOR13_1165	COG1640	4-alpha-glucanotransferase
AOR13_1166	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AOR13_1168	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOR13_117	COG4771	TonB-dependent receptor
AOR13_1173	COG2866	Carboxypeptidase
AOR13_1175	COG1115	amino acid carrier protein
AOR13_1177	COG3139	Protein of unknown function (DUF1315)
AOR13_118	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOR13_1182	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AOR13_1188	COG0784	Response regulator, receiver
AOR13_1189	COG4251	negative regulation of phosphorylation
AOR13_1191	COG2204	response regulator
AOR13_1193	COG0583	DNA-binding transcription factor activity
AOR13_1195	COG0640	Transcriptional regulator
AOR13_1199	COG0583	DNA-binding transcription factor activity
AOR13_1204	COG5001	Diguanylate cyclase
AOR13_1204	COG3300	MHYT domain
AOR13_1205	COG1022	Amp-dependent synthetase and ligase
AOR13_1207	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOR13_1208	COG1074	ATP-dependent DNA helicase activity
AOR13_1209	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOR13_1212	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOR13_1216	COG3268	Saccharopine dehydrogenase
AOR13_1217	COG0436	Aminotransferase
AOR13_122	COG3300	MHYT domain
AOR13_122	COG5001	Diguanylate cyclase
AOR13_1224	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_123	COG1573	uracil-dna glycosylase
AOR13_125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOR13_1260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOR13_1261	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOR13_1262	COG0315	cyclic pyranopterin monophosphate synthase activity
AOR13_1263	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AOR13_1264	COG0314	molybdopterin synthase activity
AOR13_1267	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AOR13_1268	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOR13_1272	COG4771	TonB-dependent receptor
AOR13_1274	COG1960	acyl-CoA dehydrogenase activity
AOR13_1280	COG0596	Alpha beta hydrolase
AOR13_1281	COG1024	Enoyl-CoA hydratase
AOR13_1281	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOR13_1282	COG0183	Belongs to the thiolase family
AOR13_1283	COG1960	acyl-CoA dehydrogenase activity
AOR13_1284	COG0596	Alpha beta hydrolase
AOR13_1286	COG2390	Transcriptional regulator
AOR13_1287	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_1289	COG0246	Mannitol dehydrogenase
AOR13_129	COG1309	transcriptional regulator
AOR13_1294	COG0668	transmembrane transport
AOR13_1299	COG0668	transmembrane transport
AOR13_13	COG0753	catalase activity
AOR13_1300	COG4771	TonB-dependent receptor
AOR13_1304	COG2205	protein histidine kinase activity
AOR13_1304	COG0784	Response regulator, receiver
AOR13_1304	COG2198	Histidine kinase
AOR13_1305	COG3437	response regulator, receiver
AOR13_1307	COG0195	Participates in both transcription termination and antitermination
AOR13_1310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOR13_1312	COG4269	membrane
AOR13_1314	COG3706	GGDEF domain
AOR13_1315	COG0596	Alpha beta hydrolase
AOR13_1317	COG3153	acetyltransferase
AOR13_1317	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOR13_1322	COG0450	alkyl hydroperoxide reductase
AOR13_1328	COG4771	TonB-dependent receptor
AOR13_1331	COG4134	Bacterial extracellular solute-binding protein
AOR13_1332	COG4135	transport system, permease component
AOR13_1333	COG4136	ATPase activity
AOR13_1334	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOR13_1337	COG2203	Gaf domain
AOR13_1337	COG3706	GGDEF domain
AOR13_1337	COG5001	Diguanylate cyclase
AOR13_1337	COG4251	negative regulation of phosphorylation
AOR13_1341	COG3300	MHYT domain
AOR13_1341	COG5001	Diguanylate cyclase
AOR13_1346	COG0583	DNA-binding transcription factor activity
AOR13_1352	COG1595	DNA-templated transcription, initiation
AOR13_1354	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_1360	COG2814	Major facilitator Superfamily
AOR13_1361	COG4771	TonB-dependent receptor
AOR13_1365	COG2867	negative regulation of translational initiation
AOR13_1366	COG2914	Belongs to the UPF0125 (RnfH) family
AOR13_1368	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOR13_1370	COG0457	Tetratricopeptide repeat
AOR13_1371	COG2318	DinB family
AOR13_1375	COG0477	Major facilitator Superfamily
AOR13_1380	COG0295	cytidine deaminase activity
AOR13_1384	COG1196	nuclear chromosome segregation
AOR13_1386	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AOR13_1389	COG1132	(ABC) transporter
AOR13_139	COG0417	DNA replication proofreading
AOR13_1397	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOR13_1398	COG0579	oxidoreductase
AOR13_1399	COG0435	Glutathione S-transferase
AOR13_1403	COG2009	succinate dehydrogenase
AOR13_1404	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AOR13_1405	COG1053	succinate dehydrogenase
AOR13_1407	COG0567	Dehydrogenase, E1 component
AOR13_1408	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOR13_141	COG4191	Histidine kinase
AOR13_1416	COG4667	esterase of the alpha-beta hydrolase superfamily
AOR13_1420	COG0366	Alpha amylase catalytic
AOR13_1423	COG1609	Transcriptional regulator
AOR13_1426	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_1427	COG2267	carboxylic ester hydrolase activity
AOR13_1429	COG0616	signal peptide processing
AOR13_143	COG0730	response to heat
AOR13_1435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOR13_1436	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOR13_1437	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOR13_1438	COG0386	Belongs to the glutathione peroxidase family
AOR13_1439	COG2084	Dehydrogenase
AOR13_1441	COG1960	acyl-CoA dehydrogenase activity
AOR13_1442	COG1024	Enoyl-CoA hydratase
AOR13_1443	COG2226	methyltransferase
AOR13_1445	COG3083	sulfuric ester hydrolase activity
AOR13_1446	COG3082	Protein of unknown function (DUF1414)
AOR13_1447	COG3081	Nucleoid-associated protein
AOR13_1453	COG3275	phosphorelay sensor kinase activity
AOR13_1454	COG3279	Response regulator of the LytR AlgR family
AOR13_1455	COG0205	6-phosphofructokinase activity
AOR13_1457	COG2205	protein histidine kinase activity
AOR13_1457	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_1476	COG3547	Transposase (IS116 IS110 IS902 family)
AOR13_1477	COG2801	Transposase and inactivated derivatives
AOR13_1480	COG0513	Belongs to the DEAD box helicase family
AOR13_1481	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOR13_1482	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOR13_1483	COG0583	DNA-binding transcription factor activity
AOR13_1487	COG1760	l-serine dehydratase
AOR13_1488	COG0494	nUDIX hydrolase
AOR13_1489	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOR13_1491	COG1322	Protein conserved in bacteria
AOR13_1492	COG1404	Belongs to the peptidase S8 family
AOR13_1493	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOR13_1494	COG0022	dehydrogenase e1 component
AOR13_1495	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOR13_1496	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOR13_1497	COG0515	serine threonine protein kinase
AOR13_1498	COG1946	Acyl-CoA thioesterase
AOR13_1500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOR13_1502	COG1956	GAF domain-containing protein
AOR13_1505	COG0793	Belongs to the peptidase S41A family
AOR13_1506	COG0733	neurotransmitter:sodium symporter activity
AOR13_1508	COG0308	aminopeptidase N
AOR13_151	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AOR13_151	COG3264	Mechanosensitive ion channel
AOR13_1514	COG2902	Dehydrogenase
AOR13_1515	COG0167	dihydroorotate dehydrogenase activity
AOR13_152	COG2186	Transcriptional regulator
AOR13_1520	COG3130	regulation of translation
AOR13_1521	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOR13_1523	COG0415	Belongs to the DNA photolyase family
AOR13_1524	COG0415	Belongs to the DNA photolyase family
AOR13_1525	COG3046	protein related to deoxyribodipyrimidine photolyase
AOR13_153	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_1531	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOR13_1532	COG0589	response to stress
AOR13_1534	COG0069	glutamate synthase activity
AOR13_1537	COG2193	ferroxidase activity
AOR13_1539	COG3278	Belongs to the heme-copper respiratory oxidase family
AOR13_154	COG0800	Aldolase
AOR13_1542	COG2010	Cytochrome c
AOR13_1547	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOR13_1549	COG0037	tRNA processing
AOR13_155	COG0513	Belongs to the DEAD box helicase family
AOR13_1550	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOR13_1554	COG1280	lysine exporter protein (LysE YggA)
AOR13_1555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOR13_1556	COG2897	thiosulfate sulfurtransferase activity
AOR13_1557	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AOR13_156	COG1131	(ABC) transporter
AOR13_156	COG0842	Transport permease protein
AOR13_156	COG1716	ATPase activity
AOR13_1569	COG0582	viral genome integration into host DNA
AOR13_1574	COG0322	excinuclease ABC activity
AOR13_1575	COG2197	response regulator
AOR13_1576	COG1741	Belongs to the pirin family
AOR13_1578	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOR13_1583	COG0642	Histidine kinase
AOR13_1584	COG0745	RESPONSE REGULATOR receiver
AOR13_1589	COG0670	Belongs to the BI1 family
AOR13_159	COG1357	PFAM Pentapeptide repeats (8 copies)
AOR13_159	COG0515	serine threonine protein kinase
AOR13_1592	COG2923	Belongs to the DsrF TusC family
AOR13_1594	COG2920	part of a sulfur-relay system
AOR13_1595	COG0561	phosphatase activity
AOR13_1598	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOR13_1599	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOR13_16	COG0667	Aldo Keto reductase
AOR13_1600	COG0531	amino acid
AOR13_1600	COG1674	ftsk spoiiie
AOR13_1602	COG0686	Belongs to the AlaDH PNT family
AOR13_1603	COG0284	orotidine-5'-phosphate decarboxylase activity
AOR13_1604	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AOR13_1605	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AOR13_1607	COG0776	regulation of translation
AOR13_1608	COG0539	negative regulation of cytoplasmic translation
AOR13_1609	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AOR13_1610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOR13_1611	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AOR13_1614	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOR13_1615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOR13_1616	COG0633	Ferredoxin
AOR13_1617	COG5002	protein histidine kinase activity
AOR13_1632	COG3547	Transposase (IS116 IS110 IS902 family)
AOR13_1638	COG1131	(ABC) transporter
AOR13_1646	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AOR13_1647	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOR13_1649	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOR13_1651	COG4783	chaperone-mediated protein folding
AOR13_1653	COG1393	Belongs to the ArsC family
AOR13_166	COG1716	ATPase activity
AOR13_1660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOR13_1665	COG0572	uridine kinase
AOR13_1666	COG3769	mannosylglycerate metabolic process
AOR13_1667	COG1215	transferase activity, transferring glycosyl groups
AOR13_1669	COG0303	'Molybdopterin
AOR13_1670	COG0534	Mate efflux family protein
AOR13_1673	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOR13_1674	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOR13_1676	COG0405	Gamma-glutamyltransferase
AOR13_1677	COG1024	Enoyl-CoA hydratase
AOR13_1685	COG1448	Aminotransferase
AOR13_1686	COG1671	Belongs to the UPF0178 family
AOR13_1687	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_1689	COG1960	acyl-CoA dehydrogenase activity
AOR13_1699	COG0596	Alpha beta hydrolase
AOR13_17	COG1283	sodium-dependent phosphate transmembrane transporter activity
AOR13_170	COG2271	Major facilitator Superfamily
AOR13_1701	COG0716	FMN binding
AOR13_1705	COG3265	gluconokinase activity
AOR13_1706	COG1609	Transcriptional regulator
AOR13_1708	COG1984	allophanate hydrolase subunit 2
AOR13_171	COG1917	Cupin 2, conserved barrel domain protein
AOR13_1710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AOR13_1711	COG1765	OsmC-like protein
AOR13_1712	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_1717	COG0436	Aminotransferase
AOR13_1718	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AOR13_1719	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AOR13_1721	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOR13_173	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_1733	COG4628	conserved protein (DUF2132)
AOR13_1735	COG0454	-acetyltransferase
AOR13_1736	COG1119	ATPase activity
AOR13_1738	COG1185	polyribonucleotide nucleotidyltransferase activity
AOR13_1744	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_1753	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOR13_1754	COG0149	triose-phosphate isomerase activity
AOR13_1755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOR13_1756	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOR13_1757	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOR13_1758	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AOR13_1760	COG1067	ATP-dependent peptidase activity
AOR13_1761	COG0495	leucyl-tRNA aminoacylation
AOR13_1763	COG1466	dna polymerase III delta subunit
AOR13_1764	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AOR13_1765	COG0799	negative regulation of ribosome biogenesis
AOR13_1766	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AOR13_1767	COG0768	penicillin binding
AOR13_1768	COG0772	Belongs to the SEDS family
AOR13_1769	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOR13_1770	COG1686	Belongs to the peptidase S11 family
AOR13_1771	COG2921	Belongs to the UPF0250 family
AOR13_1772	COG0321	lipoyl(octanoyl) transferase activity
AOR13_1773	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOR13_1775	COG0252	asparaginase activity
AOR13_1778	COG0778	Nitroreductase
AOR13_1781	COG0616	signal peptide processing
AOR13_1782	COG3091	SprT-like family
AOR13_1784	COG0492	ferredoxin-NADP+ reductase activity
AOR13_1785	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOR13_1786	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AOR13_1787	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AOR13_1789	COG0542	response to heat
AOR13_179	COG1858	cytochrome C peroxidase
AOR13_1790	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOR13_1791	COG1278	Cold shock
AOR13_1793	COG1187	pseudouridine synthase activity
AOR13_1795	COG0482	sulfurtransferase activity
AOR13_1796	COG2915	High frequency lysogenization protein hflD homolog
AOR13_1797	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOR13_1799	COG2850	peptidyl-arginine hydroxylation
AOR13_180	COG4771	TonB-dependent receptor
AOR13_1802	COG0277	FAD linked oxidase domain protein
AOR13_1802	COG0247	lactate metabolic process
AOR13_1803	COG3123	guanosine phosphorylase activity
AOR13_1804	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOR13_1813	COG1695	Transcriptional regulator
AOR13_1816	COG1077	Cell shape determining protein MreB Mrl
AOR13_1820	COG3265	gluconokinase activity
AOR13_1822	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_1825	COG1609	Transcriptional regulator
AOR13_1826	COG0679	Auxin Efflux Carrier
AOR13_1830	COG0574	Belongs to the PEP-utilizing enzyme family
AOR13_1830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOR13_1834	COG1942	4-Oxalocrotonate Tautomerase
AOR13_1838	COG1714	RDD family
AOR13_1842	COG0745	RESPONSE REGULATOR receiver
AOR13_1842	COG3706	GGDEF domain
AOR13_1843	COG0702	epimerase
AOR13_1846	COG0084	hydrolase, TatD family'
AOR13_1847	COG0470	DNA polymerase III
AOR13_1849	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOR13_1850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOR13_1851	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOR13_1852	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOR13_1855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOR13_1856	COG0416	fatty acid biosynthetic process
AOR13_1858	COG1399	metal-binding, possibly nucleic acid-binding protein
AOR13_1859	COG0424	maF-like protein
AOR13_186	COG4585	Histidine kinase
AOR13_1860	COG0546	phosphoglycolate phosphatase activity
AOR13_1862	COG1530	ribonuclease E activity
AOR13_1866	COG2153	protein acetylation
AOR13_187	COG2197	response regulator
AOR13_1871	COG0625	glutathione transferase activity
AOR13_1874	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOR13_1876	COG0583	DNA-binding transcription factor activity
AOR13_1878	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOR13_1879	COG3724	N-succinylarginine dihydrolase activity
AOR13_188	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_1881	COG1301	dicarboxylic acid transport
AOR13_1882	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOR13_1883	COG1136	(ABC) transporter
AOR13_1884	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AOR13_189	COG3901	Regulator of nitric oxide reductase transcription
AOR13_189	COG0348	domain, Protein
AOR13_1890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOR13_1891	COG0328	RNA-DNA hybrid ribonuclease activity
AOR13_1897	COG1643	Atp-dependent helicase
AOR13_1905	COG4999	Histidine kinase
AOR13_1905	COG3850	Histidine kinase
AOR13_1905	COG3437	response regulator, receiver
AOR13_1905	COG2205	protein histidine kinase activity
AOR13_1906	COG2925	Exonuclease
AOR13_1908	COG3706	GGDEF domain
AOR13_1909	COG0183	Belongs to the thiolase family
AOR13_191	COG2205	protein histidine kinase activity
AOR13_191	COG0784	Response regulator, receiver
AOR13_1910	COG0789	Transcriptional regulator
AOR13_1911	COG1960	acyl-CoA dehydrogenase activity
AOR13_1912	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOR13_1913	COG1024	Enoyl-CoA hydratase
AOR13_1920	COG1957	nucleoside hydrolase
AOR13_1923	COG2814	Major facilitator Superfamily
AOR13_1930	COG0708	Exodeoxyribonuclease III
AOR13_1933	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOR13_1935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOR13_1937	COG2096	Adenosyltransferase
AOR13_1938	COG0471	metal ion transport
AOR13_1939	COG1472	Belongs to the glycosyl hydrolase 3 family
AOR13_1941	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOR13_1944	COG0072	phenylalanine-tRNA ligase activity
AOR13_1944	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_1952	COG2244	polysaccharide biosynthetic process
AOR13_1954	COG1215	transferase activity, transferring glycosyl groups
AOR13_1957	COG0438	transferase activity, transferring glycosyl groups
AOR13_1964	COG4464	protein tyrosine phosphatase activity
AOR13_1965	COG0489	protein tyrosine kinase activity
AOR13_1966	COG1596	polysaccharide export
AOR13_1968	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOR13_197	COG0535	radical SAM domain protein
AOR13_1972	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AOR13_1983	COG0730	response to heat
AOR13_1984	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOR13_1987	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOR13_1988	COG2233	PERMEase
AOR13_199	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AOR13_1991	COG0784	Response regulator, receiver
AOR13_1991	COG5002	protein histidine kinase activity
AOR13_1992	COG0745	RESPONSE REGULATOR receiver
AOR13_1992	COG3706	GGDEF domain
AOR13_1993	COG5001	Diguanylate cyclase
AOR13_1993	COG3300	MHYT domain
AOR13_1995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOR13_1996	COG2252	PERMEase
AOR13_1999	COG1309	transcriptional regulator
AOR13_2	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOR13_20	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOR13_200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AOR13_2001	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOR13_2004	COG2351	hydroxyisourate hydrolase activity
AOR13_2005	COG0402	S-adenosylhomocysteine deaminase activity
AOR13_2007	COG5002	protein histidine kinase activity
AOR13_2007	COG5001	Diguanylate cyclase
AOR13_2007	COG3447	MASE1 domain protein
AOR13_201	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOR13_2011	COG3706	GGDEF domain
AOR13_2014	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AOR13_2018	COG2190	(PTS) system
AOR13_2018	COG2211	Major facilitator Superfamily
AOR13_2019	COG1393	Belongs to the ArsC family
AOR13_2025	COG2988	succinylglutamate desuccinylase activity
AOR13_2027	COG0058	SHG alpha-glucan phosphorylase activity
AOR13_2028	COG0033	Phosphoglucomutase
AOR13_2029	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AOR13_2030	COG0714	Associated with various cellular activities
AOR13_2033	COG2116	formate transmembrane transporter activity
AOR13_2034	COG2815	serine threonine protein kinase
AOR13_2034	COG0515	serine threonine protein kinase
AOR13_2035	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AOR13_2040	COG0583	DNA-binding transcription factor activity
AOR13_2043	COG3094	Invasion gene expression up-regulator, SirB
AOR13_2044	COG0784	Response regulator, receiver
AOR13_2044	COG3437	response regulator, receiver
AOR13_2045	COG2890	protein-(glutamine-N5) methyltransferase activity
AOR13_2047	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AOR13_2048	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AOR13_2049	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AOR13_2051	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOR13_2052	COG5001	Diguanylate cyclase
AOR13_2052	COG3300	MHYT domain
AOR13_2054	COG1064	alcohol dehydrogenase
AOR13_2057	COG0012	GTP binding
AOR13_2058	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOR13_2063	COG1115	amino acid carrier protein
AOR13_2064	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOR13_2070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOR13_2072	COG1702	phosphate starvation-inducible protein PhoH
AOR13_2074	COG4535	Mg2 and Co2 transporter CorC
AOR13_2075	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AOR13_2076	COG0857	belongs to the CobB CobQ family
AOR13_2076	COG0280	phosphate acetyltransferase
AOR13_2077	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOR13_2078	COG0071	Belongs to the small heat shock protein (HSP20) family
AOR13_2083	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOR13_2084	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AOR13_2085	COG0505	Belongs to the CarA family
AOR13_2086	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AOR13_209	COG3706	GGDEF domain
AOR13_2090	COG4251	negative regulation of phosphorylation
AOR13_2090	COG3706	GGDEF domain
AOR13_2090	COG2203	Gaf domain
AOR13_2090	COG5001	Diguanylate cyclase
AOR13_2091	COG3909	cytochrome
AOR13_2092	COG0484	heat shock protein binding
AOR13_2094	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AOR13_2095	COG0784	Response regulator, receiver
AOR13_2095	COG2205	protein histidine kinase activity
AOR13_2097	COG4771	TonB-dependent receptor
AOR13_2098	COG2610	gluconate transmembrane transporter activity
AOR13_2099	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOR13_210	COG3706	GGDEF domain
AOR13_2101	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_2103	COG0497	DNA recombination
AOR13_2104	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOR13_2105	COG0500	methyltransferase
AOR13_2106	COG2733	membrane
AOR13_2110	COG0110	maltose O-acetyltransferase activity
AOR13_2111	COG0656	L-ascorbic acid biosynthetic process
AOR13_2114	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOR13_2115	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOR13_2116	COG0009	L-threonylcarbamoyladenylate synthase
AOR13_2117	COG0613	PHP domain protein
AOR13_2118	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOR13_2120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOR13_2121	COG0135	phosphoribosylanthranilate isomerase activity
AOR13_2121	COG0134	indole-3-glycerol-phosphate synthase activity
AOR13_2123	COG0159	tryptophan synthase activity
AOR13_2124	COG2350	Protein conserved in bacteria
AOR13_2127	COG0745	RESPONSE REGULATOR receiver
AOR13_2128	COG2205	protein histidine kinase activity
AOR13_2129	COG0628	permease
AOR13_2130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOR13_2131	COG1090	epimerase
AOR13_2132	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AOR13_2133	COG4181	ATPase activity
AOR13_2137	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOR13_2145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOR13_2149	COG0745	RESPONSE REGULATOR receiver
AOR13_2151	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOR13_2152	COG5265	(ABC) transporter
AOR13_2155	COG5433	transposase activity
AOR13_2156	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AOR13_2158	COG4139	cobalamin transport
AOR13_2159	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOR13_2162	COG2226	methyltransferase
AOR13_2162	COG1073	alpha beta
AOR13_2163	COG0156	8-amino-7-oxononanoate synthase activity
AOR13_2168	COG0456	acetyltransferase
AOR13_2169	COG0189	ligase activity
AOR13_217	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_2172	COG0017	Asparaginyl-tRNA synthetase
AOR13_2174	COG2995	paraquat-inducible protein a
AOR13_2175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOR13_2175	COG3008	intermembrane lipid transfer
AOR13_2177	COG3706	GGDEF domain
AOR13_2181	COG0583	DNA-binding transcription factor activity
AOR13_2182	COG1309	transcriptional regulator
AOR13_2184	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_2185	COG0517	IMP dehydrogenase activity
AOR13_2189	COG0583	DNA-binding transcription factor activity
AOR13_219	COG4191	Histidine kinase
AOR13_2190	COG3038	cytochrome b561
AOR13_2197	COG2271	Major facilitator Superfamily
AOR13_2198	COG0784	Response regulator, receiver
AOR13_2198	COG2205	protein histidine kinase activity
AOR13_2206	COG0024	Methionine aminopeptidase
AOR13_2208	COG0745	RESPONSE REGULATOR receiver
AOR13_2208	COG3706	GGDEF domain
AOR13_2213	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOR13_2217	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AOR13_2218	COG2885	chlorophyll binding
AOR13_2219	COG0823	Involved in the tonB-independent uptake of proteins
AOR13_2222	COG0811	peptide transport
AOR13_2223	COG0824	Thioesterase
AOR13_2224	COG2255	four-way junction helicase activity
AOR13_2227	COG0494	nUDIX hydrolase
AOR13_2228	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AOR13_2231	COG2204	response regulator
AOR13_2233	COG2205	protein histidine kinase activity
AOR13_2237	COG0745	RESPONSE REGULATOR receiver
AOR13_2237	COG3706	GGDEF domain
AOR13_2239	COG0023	Translation Initiation Factor
AOR13_2240	COG0745	RESPONSE REGULATOR receiver
AOR13_2241	COG0077	Prephenate dehydratase
AOR13_2241	COG1605	Chorismate mutase
AOR13_2242	COG0840	transmembrane signaling receptor activity
AOR13_2243	COG1605	Chorismate mutase
AOR13_2243	COG0287	Prephenate dehydrogenase
AOR13_2244	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOR13_2245	COG2860	membrane
AOR13_2249	COG0335	large ribosomal subunit rRNA binding
AOR13_2250	COG0336	Belongs to the RNA methyltransferase TrmD family
AOR13_2251	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOR13_2252	COG0228	four-way junction DNA binding
AOR13_2256	COG1132	(ABC) transporter
AOR13_2257	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_2259	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOR13_2265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOR13_2266	COG4137	Cytochrome C assembly protein
AOR13_2267	COG4536	flavin adenine dinucleotide binding
AOR13_2269	COG2062	phosphohistidine phosphatase, SixA
AOR13_2270	COG1025	Belongs to the peptidase M16 family
AOR13_2274	COG1024	Enoyl-CoA hydratase
AOR13_2274	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOR13_2276	COG0714	Associated with various cellular activities
AOR13_2280	COG2304	oxidoreductase activity
AOR13_2285	COG3706	GGDEF domain
AOR13_2286	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_2287	COG0175	sulfate reduction
AOR13_2288	COG0529	Catalyzes the synthesis of activated sulfate
AOR13_2291	COG3273	potassium ion transport
AOR13_2291	COG0471	metal ion transport
AOR13_2296	COG0367	asparagine synthase
AOR13_2298	COG0602	queuosine metabolic process
AOR13_23	COG0189	ligase activity
AOR13_23	COG4067	protein conserved in archaea
AOR13_230	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOR13_2303	COG0556	nucleotide-excision repair
AOR13_2304	COG0534	Mate efflux family protein
AOR13_2307	COG4657	Part of a membrane complex involved in electron transport
AOR13_2308	COG2878	Part of a membrane complex involved in electron transport
AOR13_2309	COG4656	Part of a membrane complex involved in electron transport
AOR13_2310	COG4658	electron transport chain
AOR13_2312	COG4660	Part of a membrane complex involved in electron transport
AOR13_2313	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOR13_2315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOR13_2316	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOR13_2317	COG0823	Involved in the tonB-independent uptake of proteins
AOR13_2317	COG4946	Tricorn protease homolog
AOR13_2317	COG1506	peptidase
AOR13_2322	COG1278	Cold shock
AOR13_2323	COG0346	lactoylglutathione lyase activity
AOR13_2324	COG0584	glycerophosphoryl diester phosphodiesterase
AOR13_2325	COG2885	chlorophyll binding
AOR13_2326	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOR13_2327	COG0450	alkyl hydroperoxide reductase
AOR13_2332	COG4771	TonB-dependent receptor
AOR13_2333	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOR13_2335	COG2766	serine protein kinase
AOR13_2336	COG2718	Belongs to the UPF0229 family
AOR13_2340	COG2890	protein-(glutamine-N5) methyltransferase activity
AOR13_2347	COG1136	(ABC) transporter
AOR13_2352	COG0612	Peptidase, M16
AOR13_2354	COG0564	pseudouridine synthase activity
AOR13_2355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOR13_2356	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AOR13_2361	COG2175	clavaminate synthase activity
AOR13_2369	COG0583	DNA-binding transcription factor activity
AOR13_2372	COG0456	acetyltransferase
AOR13_2383	COG0848	biopolymer transport protein
AOR13_2384	COG0811	peptide transport
AOR13_2385	COG0811	peptide transport
AOR13_2393	COG0457	Tetratricopeptide repeat
AOR13_2397	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOR13_2398	COG1522	sequence-specific DNA binding
AOR13_2399	COG0625	glutathione transferase activity
AOR13_2406	COG1842	Phage shock protein A
AOR13_2407	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AOR13_2408	COG0747	negative chemotaxis
AOR13_2409	COG4168	peptide transport system, permease
AOR13_2410	COG4171	peptide transport system, permease
AOR13_2411	COG4172	Belongs to the ABC transporter superfamily
AOR13_2412	COG4172	Belongs to the ABC transporter superfamily
AOR13_2413	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AOR13_2416	COG1607	acyl-coa hydrolase
AOR13_2425	COG3590	peptidase
AOR13_2426	COG1309	transcriptional regulator
AOR13_2427	COG0659	secondary active sulfate transmembrane transporter activity
AOR13_2428	COG0288	reversible hydration of carbon dioxide
AOR13_2429	COG0583	DNA-binding transcription factor activity
AOR13_2430	COG0583	DNA-binding transcription factor activity
AOR13_2432	COG1410	methionine synthase
AOR13_2432	COG0646	methionine synthase
AOR13_2433	COG0646	methionine synthase
AOR13_2433	COG1410	methionine synthase
AOR13_2436	COG0835	chemotaxis
AOR13_2438	COG1192	Involved in chromosome partitioning
AOR13_2439	COG2201	protein-glutamate methylesterase activity
AOR13_2440	COG0643	Histidine kinase
AOR13_2440	COG2198	Histidine kinase
AOR13_2441	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AOR13_2444	COG0455	bacterial-type flagellum organization
AOR13_2446	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOR13_2449	COG1987	bacterial-type flagellum assembly
AOR13_2459	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOR13_246	COG1082	Xylose isomerase domain protein TIM barrel
AOR13_2460	COG1766	The M ring may be actively involved in energy transduction
AOR13_2462	COG2204	response regulator
AOR13_2463	COG3852	Histidine kinase
AOR13_2464	COG2204	response regulator
AOR13_2466	COG1086	Polysaccharide biosynthesis protein
AOR13_2467	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOR13_2468	COG1083	cytidylyl-transferase
AOR13_2470	COG2089	acid synthase
AOR13_2473	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOR13_248	COG0318	PFAM AMP-dependent synthetase and ligase
AOR13_2481	COG2089	acid synthase
AOR13_2482	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOR13_2483	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AOR13_249	COG4264	IucA IucC family
AOR13_2491	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOR13_2492	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOR13_2496	COG1256	bacterial-type flagellum assembly
AOR13_2497	COG1705	Flagellar rod assembly protein muramidase FlgJ
AOR13_2497	COG3951	Flagellar rod assembly protein muramidase FlgJ
AOR13_25	COG0189	ligase activity
AOR13_2500	COG4786	Flagellar basal body rod
AOR13_2501	COG4787	bacterial-type flagellum-dependent cell motility
AOR13_2502	COG1749	Flagellar hook protein flgE
AOR13_2503	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AOR13_2504	COG1558	bacterial-type flagellum-dependent cell motility
AOR13_2505	COG1815	bacterial-type flagellum-dependent cell motility
AOR13_2506	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOR13_2507	COG0784	Response regulator, receiver
AOR13_2507	COG0835	chemotaxis
AOR13_2515	COG2197	response regulator
AOR13_2516	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_2518	COG2885	chlorophyll binding
AOR13_2522	COG2840	Smr protein MutS2
AOR13_2524	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOR13_2524	COG0047	phosphoribosylformylglycinamidine synthase activity
AOR13_2527	COG0590	tRNA wobble adenosine to inosine editing
AOR13_2531	COG0037	tRNA processing
AOR13_2532	COG0825	malonyl-CoA metabolic process
AOR13_2533	COG0587	DNA-directed DNA polymerase activity
AOR13_2536	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOR13_2537	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOR13_2540	COG0750	zinc metalloprotease
AOR13_2541	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOR13_2542	COG0575	Belongs to the CDS family
AOR13_2543	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOR13_2545	COG0528	UMP kinase activity
AOR13_2547	COG0052	Belongs to the universal ribosomal protein uS2 family
AOR13_2549	COG0024	Methionine aminopeptidase
AOR13_2553	COG0564	pseudouridine synthase activity
AOR13_2566	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOR13_2566	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AOR13_2567	COG3706	GGDEF domain
AOR13_2567	COG0745	RESPONSE REGULATOR receiver
AOR13_2568	COG1611	Belongs to the LOG family
AOR13_2571	COG0473	3-isopropylmalate dehydrogenase activity
AOR13_2572	COG1596	polysaccharide export
AOR13_2572	COG1555	photosystem II stabilization
AOR13_2573	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOR13_2579	COG1682	transport, permease protein
AOR13_2582	COG3104	oligopeptide transport
AOR13_2583	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOR13_2584	COG2853	Lipoprotein
AOR13_2587	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOR13_2588	COG1138	Cytochrome C-type biogenesis protein
AOR13_259	COG0795	lipopolysaccharide-transporting ATPase activity
AOR13_2590	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOR13_2591	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOR13_2592	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOR13_2593	COG4133	protoheme IX ABC transporter activity
AOR13_2597	COG1668	transmembrane transport
AOR13_2598	COG4555	ABC transporter
AOR13_260	COG0795	lipopolysaccharide-transporting ATPase activity
AOR13_2601	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AOR13_2607	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOR13_2608	COG0473	3-isopropylmalate dehydrogenase activity
AOR13_261	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AOR13_2610	COG0066	3-isopropylmalate dehydratase activity
AOR13_2611	COG3437	response regulator, receiver
AOR13_2611	COG0784	Response regulator, receiver
AOR13_2613	COG3267	Type II secretory pathway component ExeA
AOR13_2613	COG3409	Peptidoglycan-binding domain 1 protein
AOR13_2616	COG0513	Belongs to the DEAD box helicase family
AOR13_2618	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOR13_262	COG2927	DNA polymerase III (CHI subunit)
AOR13_2625	COG1346	cytolysis
AOR13_263	COG0525	valine-tRNA ligase activity
AOR13_2644	COG4667	esterase of the alpha-beta hydrolase superfamily
AOR13_2651	COG0488	(ABC) transporter
AOR13_2652	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOR13_2653	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOR13_2654	COG2971	BadF BadG BcrA BcrD
AOR13_2656	COG3706	GGDEF domain
AOR13_2657	COG0419	ATPase involved in DNA repair
AOR13_2658	COG0420	3'-5' exonuclease activity
AOR13_2660	COG1739	Uncharacterized protein family UPF0029
AOR13_2663	COG1764	response to oxidative stress
AOR13_2664	COG1846	Transcriptional regulator
AOR13_2665	COG1472	Belongs to the glycosyl hydrolase 3 family
AOR13_2669	COG2207	Transcriptional regulator
AOR13_267	COG3706	GGDEF domain
AOR13_2670	COG4447	cellulose binding
AOR13_2670	COG5520	Belongs to the glycosyl hydrolase 30 family
AOR13_2670	COG3291	Pkd domain containing protein
AOR13_2672	COG2115	Belongs to the xylose isomerase family
AOR13_2673	COG1070	Carbohydrate kinase
AOR13_2674	COG2207	Transcriptional regulator
AOR13_2674	COG1609	Transcriptional regulator
AOR13_2675	COG0477	Major facilitator Superfamily
AOR13_2679	COG1272	protein, Hemolysin III
AOR13_2684	COG0583	DNA-binding transcription factor activity
AOR13_2686	COG0306	phosphate transporter
AOR13_2688	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOR13_2689	COG0573	inorganic phosphate transmembrane transporter activity
AOR13_2691	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOR13_2692	COG0248	Ppx GppA phosphatase
AOR13_2693	COG4946	Tricorn protease homolog
AOR13_2693	COG1506	peptidase
AOR13_2693	COG0823	Involved in the tonB-independent uptake of proteins
AOR13_2694	COG3588	fructose-bisphosphate aldolase
AOR13_2695	COG0126	phosphoglycerate kinase activity
AOR13_2697	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOR13_270	COG0204	Acyl-transferase
AOR13_2703	COG1979	alcohol dehydrogenase
AOR13_2705	COG2207	Transcriptional regulator
AOR13_2707	COG2205	protein histidine kinase activity
AOR13_2707	COG0784	Response regulator, receiver
AOR13_2708	COG3300	MHYT domain
AOR13_2708	COG5001	Diguanylate cyclase
AOR13_271	COG3437	response regulator, receiver
AOR13_2711	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOR13_2714	COG2207	Transcriptional regulator
AOR13_2717	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOR13_2719	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOR13_2721	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOR13_2723	COG5007	Belongs to the BolA IbaG family
AOR13_2725	COG2854	intermembrane phospholipid transfer
AOR13_2726	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOR13_2727	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOR13_2728	COG1127	ABC transporter
AOR13_273	COG3852	Histidine kinase
AOR13_2731	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOR13_2734	COG1137	ATPase activity
AOR13_2736	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOR13_2738	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOR13_2739	COG2239	Acts as a magnesium transporter
AOR13_2741	COG2207	Transcriptional regulator
AOR13_2741	COG3708	Transcriptional regulator
AOR13_2742	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_2742	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_2743	COG2969	positive regulation of protein catabolic process
AOR13_2744	COG0625	glutathione transferase activity
AOR13_2745	COG2857	Cytochrome c1
AOR13_2746	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOR13_2747	COG0723	plastoquinol--plastocyanin reductase activity
AOR13_2748	COG1473	amidohydrolase
AOR13_275	COG0174	glutamine synthetase
AOR13_2750	COG4206	TonB-dependent receptor
AOR13_2752	COG1595	DNA-templated transcription, initiation
AOR13_2753	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOR13_2757	COG3956	TIGRFAM MazG family protein
AOR13_2758	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOR13_2759	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOR13_2761	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOR13_2765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOR13_2767	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AOR13_2768	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AOR13_2769	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOR13_2770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AOR13_2772	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOR13_2773	COG0840	transmembrane signaling receptor activity
AOR13_2775	COG0527	aspartate kinase activity
AOR13_2780	COG1049	propionate catabolic process, 2-methylcitrate cycle
AOR13_2781	COG2133	pyrroloquinoline quinone binding
AOR13_2783	COG0318	PFAM AMP-dependent synthetase and ligase
AOR13_2785	COG3437	response regulator, receiver
AOR13_2786	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOR13_2788	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AOR13_2789	COG0848	biopolymer transport protein
AOR13_279	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AOR13_2790	COG0811	peptide transport
AOR13_2791	COG0811	peptide transport
AOR13_2797	COG5002	protein histidine kinase activity
AOR13_2798	COG0745	RESPONSE REGULATOR receiver
AOR13_2799	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_2799	COG4191	Histidine kinase
AOR13_280	COG1914	H( )-stimulated, divalent metal cation uptake system
AOR13_2800	COG2974	May be involved in recombination
AOR13_2802	COG1396	sequence-specific DNA binding
AOR13_2803	COG3135	benzoate transporter
AOR13_2806	COG0537	adenosine 5'-monophosphoramidase activity
AOR13_2809	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOR13_2810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOR13_2814	COG1610	YqeY-like protein
AOR13_2815	COG0358	DNA primase activity
AOR13_2816	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOR13_2821	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_2822	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_2825	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_2829	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_2830	COG1960	acyl-CoA dehydrogenase activity
AOR13_2834	COG0348	domain, Protein
AOR13_2835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOR13_2837	COG4206	TonB-dependent receptor
AOR13_2838	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOR13_2841	COG1116	anion transmembrane transporter activity
AOR13_2842	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOR13_2843	COG1116	anion transmembrane transporter activity
AOR13_2843	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOR13_2846	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOR13_2846	COG1648	precorrin-2 dehydrogenase activity
AOR13_2847	COG0243	molybdopterin cofactor binding
AOR13_2848	COG2146	nitrite reductase [NAD(P)H] activity
AOR13_2849	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOR13_2851	COG0659	secondary active sulfate transmembrane transporter activity
AOR13_2853	COG3707	response regulator
AOR13_2855	COG0671	phosphoesterase, PA-phosphatase related
AOR13_2856	COG0271	Belongs to the BolA IbaG family
AOR13_2859	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOR13_2865	COG1509	lysine 2,3-aminomutase activity
AOR13_2869	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_2870	COG4251	negative regulation of phosphorylation
AOR13_2875	COG3150	esterase
AOR13_2878	COG0494	nUDIX hydrolase
AOR13_2879	COG1538	Outer membrane efflux protein
AOR13_2883	COG1648	precorrin-2 dehydrogenase activity
AOR13_2883	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOR13_2886	COG3119	arylsulfatase activity
AOR13_289	COG0850	regulation of cytokinetic process
AOR13_2893	COG3119	arylsulfatase activity
AOR13_29	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_290	COG2894	cell division
AOR13_2915	COG2124	cytochrome p450
AOR13_2918	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_2919	COG2814	Major facilitator Superfamily
AOR13_2921	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_2922	COG1063	alcohol dehydrogenase
AOR13_2923	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_2924	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_2925	COG3119	arylsulfatase activity
AOR13_2927	COG1802	Transcriptional regulator
AOR13_2930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOR13_2932	COG0564	pseudouridine synthase activity
AOR13_2936	COG0784	Response regulator, receiver
AOR13_2936	COG5002	protein histidine kinase activity
AOR13_2937	COG3706	GGDEF domain
AOR13_2938	COG2201	protein-glutamate methylesterase activity
AOR13_2939	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AOR13_294	COG0625	glutathione transferase activity
AOR13_2940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AOR13_2941	COG0730	response to heat
AOR13_2942	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AOR13_2944	COG3025	triphosphatase activity
AOR13_2945	COG4991	sh3 domain protein
AOR13_2946	COG2205	protein histidine kinase activity
AOR13_2946	COG2770	Histidine kinase
AOR13_2948	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOR13_2951	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOR13_2951	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOR13_2951	COG0506	proline dehydrogenase activity
AOR13_2952	COG0840	transmembrane signaling receptor activity
AOR13_2954	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AOR13_2957	COG0585	pseudouridine synthase activity
AOR13_2958	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOR13_2960	COG1238	metal cluster binding
AOR13_297	COG1902	pentaerythritol trinitrate reductase activity
AOR13_2972	COG0142	geranyltranstransferase activity
AOR13_2974	COG0006	proline dipeptidase activity
AOR13_2977	COG1024	Enoyl-CoA hydratase
AOR13_2977	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOR13_2978	COG0183	Belongs to the thiolase family
AOR13_298	COG3659	wide pore channel activity
AOR13_299	COG0738	Major facilitator superfamily
AOR13_2991	COG3547	Transposase (IS116 IS110 IS902 family)
AOR13_2995	COG2161	toxin-antitoxin pair type II binding
AOR13_3	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AOR13_3	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AOR13_30	COG0517	IMP dehydrogenase activity
AOR13_30	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOR13_3008	COG0346	lactoylglutathione lyase activity
AOR13_301	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOR13_3013	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AOR13_3014	COG3876	Protein conserved in bacteria
AOR13_3018	COG1757	Na H antiporter
AOR13_302	COG0739	heme binding
AOR13_3022	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_3024	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AOR13_3026	COG3118	belongs to the thioredoxin family
AOR13_3028	COG2133	pyrroloquinoline quinone binding
AOR13_3029	COG0783	Belongs to the Dps family
AOR13_3032	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOR13_3034	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOR13_3035	COG0784	Response regulator, receiver
AOR13_3035	COG2205	protein histidine kinase activity
AOR13_3037	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AOR13_3038	COG3118	belongs to the thioredoxin family
AOR13_3039	COG0513	Belongs to the DEAD box helicase family
AOR13_3040	COG0248	Ppx GppA phosphatase
AOR13_3042	COG3706	GGDEF domain
AOR13_3045	COG0805	protein transport
AOR13_3046	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AOR13_3050	COG0028	Belongs to the TPP enzyme family
AOR13_3053	COG0457	Tetratricopeptide repeat
AOR13_3057	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOR13_3059	COG1162	GTPase activity
AOR13_306	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOR13_3062	COG0584	glycerophosphoryl diester phosphodiesterase
AOR13_3064	COG2861	carbohydrate metabolic process
AOR13_3066	COG4942	peptidase
AOR13_3068	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOR13_307	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOR13_3071	COG2205	protein histidine kinase activity
AOR13_3072	COG0745	RESPONSE REGULATOR receiver
AOR13_3075	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AOR13_3077	COG1803	Methylglyoxal synthase
AOR13_3080	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AOR13_3081	COG0137	argininosuccinate synthase activity
AOR13_3083	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AOR13_3083	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AOR13_3084	COG5001	Diguanylate cyclase
AOR13_3084	COG3300	MHYT domain
AOR13_309	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOR13_3091	COG0625	glutathione transferase activity
AOR13_3093	COG0281	malic enzyme
AOR13_3094	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOR13_3101	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AOR13_3104	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AOR13_3109	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOR13_3110	COG0180	Tryptophanyl-tRNA synthetase
AOR13_3111	COG0512	Glutamine amidotransferase of anthranilate synthase
AOR13_3113	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOR13_3115	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_312	COG3866	Pectate lyase
AOR13_3120	COG4999	Histidine kinase
AOR13_3120	COG2205	protein histidine kinase activity
AOR13_3120	COG3437	response regulator, receiver
AOR13_3120	COG3850	Histidine kinase
AOR13_3125	COG0540	Belongs to the ATCase OTCase family
AOR13_3128	COG2837	iron assimilation
AOR13_3129	COG0405	Gamma-glutamyltransferase
AOR13_3131	COG0004	ammonium transporteR
AOR13_3136	COG2354	Protein conserved in bacteria
AOR13_3138	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOR13_3140	COG2951	lytic endotransglycosylase activity
AOR13_3141	COG1643	Atp-dependent helicase
AOR13_3143	COG0788	formyltetrahydrofolate deformylase activity
AOR13_3150	COG1519	Transferase
AOR13_3151	COG0859	PFAM glycosyl transferase family 9
AOR13_3152	COG0438	transferase activity, transferring glycosyl groups
AOR13_3153	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AOR13_3156	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AOR13_3158	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AOR13_3160	COG0089	rRNA binding
AOR13_3163	COG0051	transcription antitermination factor activity, RNA binding
AOR13_3168	COG1454	alcohol dehydrogenase
AOR13_3176	COG2211	Major facilitator Superfamily
AOR13_3178	COG0673	inositol 2-dehydrogenase activity
AOR13_3179	COG1609	Transcriptional regulator
AOR13_318	COG1476	TRANSCRIPTIONal
AOR13_3190	COG0501	Belongs to the peptidase M48B family
AOR13_3193	COG2201	protein-glutamate methylesterase activity
AOR13_3194	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AOR13_3197	COG0835	chemotaxis
AOR13_3198	COG2198	Histidine kinase
AOR13_3198	COG0643	Histidine kinase
AOR13_3199	COG0745	RESPONSE REGULATOR receiver
AOR13_32	COG3706	GGDEF domain
AOR13_32	COG0745	RESPONSE REGULATOR receiver
AOR13_320	COG0493	'glutamate synthase
AOR13_321	COG0067	glutamate synthase
AOR13_321	COG0069	glutamate synthase activity
AOR13_321	COG0070	glutamate synthase
AOR13_3211	COG1194	a g-specific adenine glycosylase
AOR13_3213	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOR13_3215	COG0297	glycogen (starch) synthase activity
AOR13_3216	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_3216	COG4191	Histidine kinase
AOR13_3217	COG0745	RESPONSE REGULATOR receiver
AOR13_322	COG0784	Response regulator, receiver
AOR13_322	COG2198	Histidine kinase
AOR13_322	COG5002	protein histidine kinase activity
AOR13_3220	COG0312	modulator of DNA gyrase
AOR13_3221	COG3028	Belongs to the UPF0307 family
AOR13_3223	COG0312	modulator of DNA gyrase
AOR13_3224	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOR13_3226	COG1530	ribonuclease E activity
AOR13_3228	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AOR13_3229	COG1792	Involved in formation and maintenance of cell shape
AOR13_3230	COG1077	Cell shape determining protein MreB Mrl
AOR13_3238	COG1459	type II secretion system
AOR13_3239	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOR13_3241	COG3409	Peptidoglycan-binding domain 1 protein
AOR13_3241	COG3267	Type II secretory pathway component ExeA
AOR13_3249	COG1349	DNA-binding transcription factor activity
AOR13_3254	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_3261	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOR13_3263	COG0745	RESPONSE REGULATOR receiver
AOR13_3266	COG4615	Cyclic peptide transporter
AOR13_3270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOR13_3271	COG3710	Transcriptional regulator
AOR13_3279	COG0629	single-stranded DNA binding
AOR13_3282	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AOR13_3283	COG1085	galactose-1-phosphate uridylyltransferase
AOR13_3287	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOR13_3288	COG2814	Major facilitator Superfamily
AOR13_3289	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOR13_3294	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOR13_3297	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOR13_3298	COG0163	prenyltransferase activity
AOR13_3304	COG0019	diaminopimelate decarboxylase activity
AOR13_3305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AOR13_3308	COG1011	Hydrolase
AOR13_331	COG3706	GGDEF domain
AOR13_3311	COG0745	RESPONSE REGULATOR receiver
AOR13_3311	COG3706	GGDEF domain
AOR13_3313	COG2239	Acts as a magnesium transporter
AOR13_3314	COG2050	protein possibly involved in aromatic compounds catabolism
AOR13_3315	COG0514	ATP-dependent DNA helicase (RecQ)
AOR13_3317	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AOR13_3319	COG5001	Diguanylate cyclase
AOR13_3319	COG5002	protein histidine kinase activity
AOR13_332	COG2828	Protein conserved in bacteria
AOR13_3320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOR13_3321	COG3064	Membrane
AOR13_3323	COG0840	transmembrane signaling receptor activity
AOR13_3325	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOR13_3326	COG0427	acetyl-CoA hydrolase
AOR13_3328	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOR13_3329	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_3332	COG2076	Multidrug Resistance protein
AOR13_3334	COG0583	DNA-binding transcription factor activity
AOR13_3336	COG5001	Diguanylate cyclase
AOR13_3336	COG5002	protein histidine kinase activity
AOR13_3336	COG3447	MASE1 domain protein
AOR13_334	COG0372	Belongs to the citrate synthase family
AOR13_3341	COG0668	transmembrane transport
AOR13_3342	COG2081	HI0933 family
AOR13_3343	COG3842	ATPase activity
AOR13_3344	COG1178	ABC-type Fe3 transport system permease component
AOR13_3347	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOR13_3347	COG0678	peroxiredoxin activity
AOR13_3349	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOR13_3350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOR13_3352	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOR13_3354	COG0194	GDP metabolic process
AOR13_3356	COG0745	RESPONSE REGULATOR receiver
AOR13_3356	COG3706	GGDEF domain
AOR13_3357	COG0181	hydroxymethylbilane synthase activity
AOR13_3359	COG2959	enzyme of heme biosynthesis
AOR13_336	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOR13_3360	COG3071	HemY protein
AOR13_3362	COG1953	Uracil, thiamine, allantoin
AOR13_3367	COG1309	transcriptional regulator
AOR13_3368	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AOR13_3369	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AOR13_3372	COG0778	Nitroreductase
AOR13_3372	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AOR13_3374	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOR13_3375	COG4771	TonB-dependent receptor
AOR13_3378	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOR13_3381	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AOR13_3385	COG3106	COG3106 Predicted ATPase
AOR13_3388	COG0583	DNA-binding transcription factor activity
AOR13_3389	COG1960	acyl-CoA dehydrogenase activity
AOR13_339	COG4771	TonB-dependent receptor
AOR13_3391	COG0842	Transport permease protein
AOR13_3392	COG0842	Transport permease protein
AOR13_3392	COG1129	ABC transporter
AOR13_3393	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOR13_3396	COG0583	DNA-binding transcription factor activity
AOR13_3397	COG4773	Receptor
AOR13_3398	COG4999	Histidine kinase
AOR13_3398	COG3850	Histidine kinase
AOR13_3398	COG3437	response regulator, receiver
AOR13_3398	COG2205	protein histidine kinase activity
AOR13_3399	COG0457	Tetratricopeptide repeat
AOR13_34	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AOR13_340	COG2197	response regulator
AOR13_3400	COG4771	TonB-dependent receptor
AOR13_3401	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_3403	COG4948	Mandelate Racemase Muconate Lactonizing
AOR13_3404	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_3408	COG0583	DNA-binding transcription factor activity
AOR13_3409	COG1760	l-serine dehydratase
AOR13_341	COG4585	Histidine kinase
AOR13_3410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOR13_3417	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AOR13_3418	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOR13_3418	COG1017	nitric oxide dioxygenase activity
AOR13_3420	COG4638	Rieske (2fe-2S)
AOR13_3424	COG1902	pentaerythritol trinitrate reductase activity
AOR13_3424	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOR13_3426	COG0247	lactate metabolic process
AOR13_3426	COG2181	nitrate reductase activity
AOR13_3429	COG1620	l-lactate permease
AOR13_3430	COG0556	nucleotide-excision repair
AOR13_3432	COG0326	Molecular chaperone. Has ATPase activity
AOR13_3438	COG0653	protein targeting
AOR13_3442	COG0210	DNA helicase
AOR13_3443	COG2960	long-chain fatty acid transporting porin activity
AOR13_3444	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOR13_3445	COG3161	chorismate lyase activity
AOR13_3447	COG0705	Rhomboid family
AOR13_3448	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOR13_3450	COG0156	8-amino-7-oxononanoate synthase activity
AOR13_3455	COG0859	PFAM glycosyl transferase family 9
AOR13_3456	COG3642	lipopolysaccharide core region biosynthetic process
AOR13_3464	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOR13_3469	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOR13_3472	COG2234	aminopeptidase activity
AOR13_3476	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AOR13_3493	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOR13_3496	COG3047	cAMP biosynthetic process
AOR13_3497	COG0408	coproporphyrinogen oxidase activity
AOR13_3498	COG0009	L-threonylcarbamoyladenylate synthase
AOR13_350	COG2823	Periplasmic or secreted lipoprotein
AOR13_3501	COG0758	DNA mediated transformation
AOR13_3505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOR13_3505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOR13_3506	COG0569	domain protein
AOR13_3507	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOR13_3508	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AOR13_3509	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOR13_3509	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOR13_3512	COG3078	GTPase activator activity
AOR13_3515	COG2818	Glycosylase
AOR13_352	COG0792	nuclease activity
AOR13_3520	COG0187	DNA topoisomerase II activity
AOR13_3521	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AOR13_3524	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AOR13_3525	COG0594	ribonuclease P activity
AOR13_3526	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AOR13_3527	COG0706	membrane insertase activity
AOR13_3529	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AOR13_353	COG3107	peptidoglycan biosynthetic process
AOR13_3530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOR13_3535	COG1192	Involved in chromosome partitioning
AOR13_3536	COG1475	DNA binding
AOR13_3539	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AOR13_354	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AOR13_3540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AOR13_3544	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AOR13_3550	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AOR13_3550	COG2199	diguanylate cyclase activity
AOR13_3553	COG1609	Transcriptional regulator
AOR13_3554	COG2211	Major facilitator Superfamily
AOR13_3560	COG1561	YicC-like family, N-terminal region
AOR13_3563	COG0425	Belongs to the sulfur carrier protein TusA family
AOR13_357	COG1748	Saccharopine dehydrogenase
AOR13_3573	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOR13_3578	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOR13_3580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOR13_3585	COG2911	Protein conserved in bacteria
AOR13_3586	COG0729	surface antigen
AOR13_3589	COG2814	Major facilitator Superfamily
AOR13_3591	COG0583	DNA-binding transcription factor activity
AOR13_3592	COG0606	chelatase, subunit chli
AOR13_3594	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOR13_3595	COG0129	dihydroxy-acid dehydratase activity
AOR13_3601	COG1565	acr, cog1565
AOR13_3601	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOR13_3602	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOR13_3603	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AOR13_3608	COG1612	heme a metabolic process
AOR13_3609	COG0109	protoheme IX farnesyltransferase activity
AOR13_3610	COG1999	signal sequence binding
AOR13_3613	COG0534	Mate efflux family protein
AOR13_3614	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AOR13_3617	COG1794	racemase activity, acting on amino acids and derivatives
AOR13_362	COG5002	protein histidine kinase activity
AOR13_3621	COG1040	competence protein
AOR13_3622	COG0596	Alpha beta hydrolase
AOR13_3625	COG2183	response to ionizing radiation
AOR13_3626	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOR13_3628	COG0545	Peptidyl-prolyl cis-trans isomerase
AOR13_363	COG0745	RESPONSE REGULATOR receiver
AOR13_3633	COG0488	(ABC) transporter
AOR13_3635	COG0429	hydrolase of the alpha beta-hydrolase fold
AOR13_3636	COG3089	Belongs to the UPF0270 family
AOR13_3639	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AOR13_364	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AOR13_3642	COG1218	3'(2'),5'-bisphosphate nucleotidase
AOR13_3643	COG0494	nUDIX hydrolase
AOR13_3644	COG1011	Hydrolase
AOR13_3647	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_3648	COG1234	tRNA 3'-trailer cleavage
AOR13_365	COG2201	protein-glutamate methylesterase activity
AOR13_3650	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AOR13_3653	COG4795	General secretion pathway protein
AOR13_3654	COG2165	general secretion pathway protein
AOR13_3656	COG2165	general secretion pathway protein
AOR13_3657	COG1459	type II secretion system
AOR13_3658	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOR13_366	COG0431	NADPH-dependent FMN reductase
AOR13_3660	COG3031	protein transport across the cell outer membrane
AOR13_3662	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AOR13_3667	COG0745	RESPONSE REGULATOR receiver
AOR13_3670	COG2233	PERMEase
AOR13_3671	COG3954	Phosphoribulokinase
AOR13_3674	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOR13_3676	COG0151	Belongs to the GarS family
AOR13_3679	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AOR13_368	COG0640	Transcriptional regulator
AOR13_3680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOR13_3684	COG0154	amidase activity
AOR13_3689	COG2176	DNA-directed DNA polymerase activity
AOR13_3693	COG0439	Biotin carboxylase
AOR13_3694	COG0511	ligase activity, forming carbon-carbon bonds
AOR13_3695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AOR13_3696	COG0739	heme binding
AOR13_3697	COG4232	protein-disulfide reductase activity
AOR13_3704	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOR13_3707	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOR13_3708	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AOR13_3709	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AOR13_3712	COG1166	arginine decarboxylase activity
AOR13_3714	COG4977	sequence-specific DNA binding
AOR13_3715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOR13_3716	COG0697	spore germination
AOR13_372	COG4585	Histidine kinase
AOR13_3720	COG1349	DNA-binding transcription factor activity
AOR13_3721	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOR13_3725	COG4771	TonB-dependent receptor
AOR13_3728	COG0523	cobalamin synthesis protein
AOR13_373	COG2197	response regulator
AOR13_3732	COG4181	ATPase activity
AOR13_3734	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOR13_3740	COG2203	Gaf domain
AOR13_3740	COG5001	Diguanylate cyclase
AOR13_3740	COG3706	GGDEF domain
AOR13_3740	COG4251	negative regulation of phosphorylation
AOR13_3741	COG2130	NADP-dependent
AOR13_3743	COG2067	long-chain fatty acid transport protein
AOR13_375	COG0583	DNA-binding transcription factor activity
AOR13_3750	COG1252	NADH dehydrogenase
AOR13_3751	COG2353	YceI-like domain
AOR13_3752	COG3038	cytochrome b561
AOR13_3757	COG2267	carboxylic ester hydrolase activity
AOR13_3766	COG3237	CsbD-like
AOR13_377	COG0083	homoserine kinase activity
AOR13_3775	COG4319	ketosteroid isomerase
AOR13_3781	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AOR13_3788	COG2204	response regulator
AOR13_3791	COG1294	oxidase, subunit
AOR13_3793	COG4988	ABC transporter
AOR13_3794	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AOR13_3795	COG4771	TonB-dependent receptor
AOR13_38	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOR13_3803	COG1230	cation diffusion facilitator family transporter
AOR13_3804	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOR13_3808	COG0656	L-ascorbic acid biosynthetic process
AOR13_3809	COG2175	clavaminate synthase activity
AOR13_3810	COG2855	membrane
AOR13_3813	COG1472	Belongs to the glycosyl hydrolase 3 family
AOR13_3815	COG4206	TonB-dependent receptor
AOR13_3817	COG4558	Periplasmic binding protein
AOR13_3818	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOR13_3819	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AOR13_3821	COG2723	6-phospho-beta-galactosidase activity
AOR13_3822	COG2211	Major facilitator Superfamily
AOR13_3823	COG1609	Transcriptional regulator
AOR13_3825	COG4191	Histidine kinase
AOR13_3825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOR13_3828	COG5002	protein histidine kinase activity
AOR13_3834	COG2258	MOSC domain
AOR13_3839	COG0305	Participates in initiation and elongation during chromosome replication
AOR13_384	COG0625	glutathione transferase activity
AOR13_3841	COG0432	Pfam Uncharacterised protein family UPF0047
AOR13_3843	COG0735	belongs to the Fur family
AOR13_3844	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AOR13_3845	COG2816	NAD+ diphosphatase activity
AOR13_3846	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOR13_3848	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOR13_3849	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOR13_3849	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOR13_385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOR13_3850	COG0802	atpase or kinase
AOR13_3853	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AOR13_3854	COG1923	regulation of RNA biosynthetic process
AOR13_3855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOR13_3856	COG0330	HflC and HflK could
AOR13_3857	COG0330	HflC and HflK could
AOR13_3858	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AOR13_3859	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOR13_3862	COG1012	belongs to the aldehyde dehydrogenase family
AOR13_3864	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOR13_3865	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AOR13_3868	COG0625	glutathione transferase activity
AOR13_3871	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_3873	COG1793	dna ligase
AOR13_3876	COG1201	RNA secondary structure unwinding
AOR13_3877	COG3306	glycosyltransferase involved in LPS biosynthesis
AOR13_388	COG1902	pentaerythritol trinitrate reductase activity
AOR13_388	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOR13_3880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOR13_3881	COG2957	Belongs to the agmatine deiminase family
AOR13_3886	COG0302	gtp cyclohydrolase
AOR13_3890	COG0346	lactoylglutathione lyase activity
AOR13_3891	COG4989	oxidoreductase activity
AOR13_3892	COG3040	lipid binding
AOR13_3894	COG0418	dihydroorotase activity
AOR13_3895	COG0513	Belongs to the DEAD box helicase family
AOR13_3897	COG3590	peptidase
AOR13_3899	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOR13_39	COG0572	uridine kinase
AOR13_3900	COG1132	(ABC) transporter
AOR13_3902	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOR13_3903	COG0250	Participates in transcription elongation, termination and antitermination
AOR13_3904	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOR13_3905	COG0081	regulation of translation
AOR13_3906	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AOR13_3907	COG0222	ribosome binding
AOR13_3908	COG0085	RNA polymerase activity
AOR13_3909	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOR13_391	COG0762	integral membrane protein
AOR13_3910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AOR13_3911	COG0049	tRNA binding
AOR13_3912	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AOR13_392	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOR13_3923	COG1966	Carbon starvation protein
AOR13_3924	COG0701	Predicted permease
AOR13_3925	COG1253	flavin adenine dinucleotide binding
AOR13_3929	COG4774	siderophore transport
AOR13_393	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOR13_3930	COG2205	protein histidine kinase activity
AOR13_3931	COG0745	RESPONSE REGULATOR receiver
AOR13_3933	COG1131	(ABC) transporter
AOR13_3934	COG0842	Transport permease protein
AOR13_3936	COG5001	Diguanylate cyclase
AOR13_3936	COG5002	protein histidine kinase activity
AOR13_3938	COG0076	glutamate decarboxylase activity
AOR13_3941	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOR13_3943	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOR13_3944	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOR13_3948	COG2095	MarC family integral membrane protein
AOR13_3950	COG0552	protein localization to endoplasmic reticulum
AOR13_3951	COG2884	Cell division ATP-binding protein ftsE
AOR13_3952	COG2177	Part of the ABC transporter FtsEX involved in
AOR13_3953	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOR13_3954	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AOR13_3957	COG0456	acetyltransferase
AOR13_3963	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOR13_3964	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AOR13_3965	COG0281	malic enzyme
AOR13_3968	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOR13_3969	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOR13_397	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOR13_3970	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AOR13_398	COG1678	Uncharacterized ACR, COG1678
AOR13_3980	COG4946	Tricorn protease homolog
AOR13_3980	COG0793	Belongs to the peptidase S41A family
AOR13_3981	COG0243	molybdopterin cofactor binding
AOR13_3982	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOR13_3986	COG2201	protein-glutamate methylesterase activity
AOR13_3988	COG0339	signal peptide processing
AOR13_399	COG0189	ligase activity
AOR13_3992	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOR13_3993	COG1278	Cold shock
AOR13_3996	COG1522	sequence-specific DNA binding
AOR13_3997	COG0840	transmembrane signaling receptor activity
AOR13_3998	COG1294	oxidase, subunit
AOR13_3999	COG1271	oxidase subunit
AOR13_4	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AOR13_400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOR13_4003	COG2234	aminopeptidase activity
AOR13_4004	COG0543	2 iron, 2 sulfur cluster binding
AOR13_4008	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AOR13_4011	COG0557	exoribonuclease II activity
AOR13_4015	COG0784	Response regulator, receiver
AOR13_4015	COG5002	protein histidine kinase activity
AOR13_402	COG0668	transmembrane transport
AOR13_4022	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AOR13_4026	COG0201	protein transport
AOR13_4031	COG0202	RNA polymerase activity
AOR13_4033	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AOR13_4033	COG0662	Cupin 2, conserved barrel domain protein
AOR13_4035	COG0438	transferase activity, transferring glycosyl groups
AOR13_4035	COG1216	Glycosyl transferase, family 2
AOR13_4038	COG3119	arylsulfatase activity
AOR13_4041	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AOR13_4046	COG0438	transferase activity, transferring glycosyl groups
AOR13_4046	COG1216	Glycosyl transferase, family 2
AOR13_406	COG2198	Histidine kinase
AOR13_406	COG5002	protein histidine kinase activity
AOR13_406	COG0784	Response regulator, receiver
AOR13_407	COG2204	response regulator
AOR13_410	COG2203	Gaf domain
AOR13_410	COG5001	Diguanylate cyclase
AOR13_410	COG3706	GGDEF domain
AOR13_410	COG4251	negative regulation of phosphorylation
AOR13_411	COG0678	peroxiredoxin activity
AOR13_411	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOR13_419	COG2001	Belongs to the MraZ family
AOR13_421	COG3116	cell division
AOR13_422	COG0768	penicillin binding
AOR13_423	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOR13_424	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOR13_426	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AOR13_427	COG0772	Belongs to the SEDS family
AOR13_429	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOR13_430	COG1181	Belongs to the D-alanine--D-alanine ligase family
AOR13_432	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AOR13_433	COG0739	heme binding
AOR13_435	COG0494	nUDIX hydrolase
AOR13_436	COG2988	succinylglutamate desuccinylase activity
AOR13_438	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AOR13_439	COG0237	dephospho-CoA kinase activity
AOR13_439	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOR13_441	COG1459	type II secretion system
AOR13_442	COG4969	Belongs to the N-Me-Phe pilin family
AOR13_448	COG2186	Transcriptional regulator
AOR13_449	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AOR13_45	COG1438	arginine binding
AOR13_450	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOR13_451	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOR13_458	COG3313	Fe-S protein
AOR13_46	COG0039	L-malate dehydrogenase activity
AOR13_462	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOR13_463	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AOR13_464	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOR13_466	COG1957	nucleoside hydrolase
AOR13_467	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOR13_469	COG0006	proline dipeptidase activity
AOR13_470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOR13_471	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOR13_476	COG1629	transport
AOR13_476	COG4206	TonB-dependent receptor
AOR13_478	COG0477	Major facilitator Superfamily
AOR13_480	COG1621	beta-fructofuranosidase activity
AOR13_484	COG0583	DNA-binding transcription factor activity
AOR13_49	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AOR13_494	COG2801	Transposase and inactivated derivatives
AOR13_50	COG0545	Peptidyl-prolyl cis-trans isomerase
AOR13_501	COG0656	L-ascorbic acid biosynthetic process
AOR13_503	COG2814	Major facilitator Superfamily
AOR13_51	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AOR13_514	COG0513	Belongs to the DEAD box helicase family
AOR13_515	COG3813	Protein conserved in bacteria
AOR13_516	COG0697	spore germination
AOR13_518	COG2133	pyrroloquinoline quinone binding
AOR13_525	COG0653	protein targeting
AOR13_528	COG1451	nucleotide metabolic process
AOR13_532	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOR13_535	COG4249	Peptidase C14 caspase catalytic subunit p20
AOR13_535	COG2319	Wd-40 repeat
AOR13_539	COG3604	Transcriptional regulator
AOR13_54	COG1805	sodium ion transport
AOR13_542	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOR13_542	COG1017	nitric oxide dioxygenase activity
AOR13_543	COG0484	heat shock protein binding
AOR13_545	COG0583	DNA-binding transcription factor activity
AOR13_549	COG4681	YaeQ
AOR13_55	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOR13_550	COG0514	ATP-dependent DNA helicase (RecQ)
AOR13_551	COG1295	ribonuclease BN
AOR13_553	COG1846	Transcriptional regulator
AOR13_554	COG1566	PFAM secretion protein HlyD family protein
AOR13_56	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOR13_562	COG4771	TonB-dependent receptor
AOR13_566	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AOR13_567	COG1335	isochorismatase
AOR13_568	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AOR13_57	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AOR13_573	COG2801	Transposase and inactivated derivatives
AOR13_576	COG1230	cation diffusion facilitator family transporter
AOR13_58	COG2871	sodium ion transport
AOR13_587	COG0693	protein deglycase activity
AOR13_588	COG4221	oxidoreductase activity
AOR13_59	COG1477	protein flavinylation
AOR13_590	COG0583	DNA-binding transcription factor activity
AOR13_593	COG0109	protoheme IX farnesyltransferase activity
AOR13_596	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOR13_597	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOR13_599	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_606	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOR13_609	COG1733	regulation of RNA biosynthetic process
AOR13_611	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_614	COG0583	DNA-binding transcription factor activity
AOR13_62	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_628	COG0826	peptidase U32
AOR13_629	COG1607	acyl-coa hydrolase
AOR13_634	COG3706	GGDEF domain
AOR13_641	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOR13_643	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOR13_649	COG1960	acyl-CoA dehydrogenase activity
AOR13_65	COG1522	sequence-specific DNA binding
AOR13_657	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOR13_660	COG0189	ligase activity
AOR13_663	COG0789	Transcriptional regulator
AOR13_665	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AOR13_668	COG4682	membrane
AOR13_669	COG1629	transport
AOR13_669	COG4774	siderophore transport
AOR13_673	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_676	COG4774	siderophore transport
AOR13_682	COG0515	serine threonine protein kinase
AOR13_682	COG2815	serine threonine protein kinase
AOR13_687	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AOR13_688	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOR13_689	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOR13_69	COG0121	glutamine amidotransferase
AOR13_690	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AOR13_697	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AOR13_699	COG1609	Transcriptional regulator
AOR13_70	COG0583	DNA-binding transcription factor activity
AOR13_701	COG1435	thymidine kinase activity
AOR13_704	COG1960	acyl-CoA dehydrogenase activity
AOR13_710	COG1560	Kdo2-lipid A biosynthetic process
AOR13_714	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AOR13_714	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AOR13_715	COG3267	Type II secretory pathway component ExeA
AOR13_715	COG3409	Peptidoglycan-binding domain 1 protein
AOR13_717	COG0489	protein tyrosine kinase activity
AOR13_72	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_724	COG1216	Glycosyl transferase, family 2
AOR13_724	COG0463	Glycosyl transferase, family 2
AOR13_73	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOR13_733	COG0438	transferase activity, transferring glycosyl groups
AOR13_738	COG1045	serine acetyltransferase
AOR13_739	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOR13_75	COG5001	Diguanylate cyclase
AOR13_75	COG5002	protein histidine kinase activity
AOR13_751	COG1785	Belongs to the alkaline phosphatase family
AOR13_752	COG2066	Belongs to the glutaminase family
AOR13_755	COG0754	glutathionylspermidine amidase activity
AOR13_760	COG1842	Phage shock protein A
AOR13_761	COG3789	protein conserved in bacteria
AOR13_764	COG0343	queuine tRNA-ribosyltransferase activity
AOR13_765	COG1862	Preprotein translocase
AOR13_766	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOR13_767	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOR13_772	COG0483	inositol monophosphate 1-phosphatase activity
AOR13_773	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AOR13_776	COG1104	cysteine desulfurase activity
AOR13_777	COG0719	Fe-S assembly protein
AOR13_778	COG0396	ATPase activity
AOR13_779	COG0719	Fe-S assembly protein
AOR13_78	COG0702	epimerase
AOR13_780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOR13_783	COG2166	iron-sulfur cluster assembly
AOR13_785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AOR13_79	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AOR13_790	COG2976	Protein conserved in bacteria
AOR13_791	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOR13_797	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOR13_798	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AOR13_801	COG1720	tRNA m6t6A37 methyltransferase activity
AOR13_809	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOR13_810	COG0740	serine-type endopeptidase activity
AOR13_811	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AOR13_814	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AOR13_815	COG0776	regulation of translation
AOR13_817	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOR13_823	COG0385	Bile acid
AOR13_824	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_827	COG0268	Binds directly to 16S ribosomal RNA
AOR13_828	COG0728	peptidoglycan biosynthetic process
AOR13_829	COG0196	riboflavin kinase activity
AOR13_830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOR13_832	COG1047	Peptidyl-prolyl cis-trans
AOR13_833	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AOR13_845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOR13_849	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AOR13_85	COG0457	Tetratricopeptide repeat
AOR13_852	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOR13_853	COG1595	DNA-templated transcription, initiation
AOR13_859	COG0681	Belongs to the peptidase S26 family
AOR13_863	COG0084	hydrolase, TatD family'
AOR13_865	COG0560	Phosphoserine phosphatase
AOR13_867	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOR13_869	COG0488	(ABC) transporter
AOR13_87	COG0848	biopolymer transport protein
AOR13_870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOR13_873	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOR13_873	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOR13_876	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AOR13_878	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOR13_879	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOR13_881	COG0142	geranyltranstransferase activity
AOR13_882	COG1722	exodeoxyribonuclease VII activity
AOR13_883	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOR13_885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOR13_889	COG4221	oxidoreductase activity
AOR13_892	COG1595	DNA-templated transcription, initiation
AOR13_895	COG0564	pseudouridine synthase activity
AOR13_897	COG0542	response to heat
AOR13_90	COG0716	FMN binding
AOR13_901	COG1183	phosphatidylcholine synthase activity
AOR13_908	COG5001	Diguanylate cyclase
AOR13_908	COG4251	negative regulation of phosphorylation
AOR13_908	COG3706	GGDEF domain
AOR13_908	COG2203	Gaf domain
AOR13_911	COG2319	Wd-40 repeat
AOR13_911	COG4249	Peptidase C14 caspase catalytic subunit p20
AOR13_913	COG3220	belongs to the UPF0276 family
AOR13_915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOR13_916	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOR13_922	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOR13_923	COG0326	Molecular chaperone. Has ATPase activity
AOR13_929	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOR13_93	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOR13_931	COG0745	RESPONSE REGULATOR receiver
AOR13_932	COG0642	Histidine kinase
AOR13_936	COG0463	Glycosyl transferase, family 2
AOR13_940	COG1022	Amp-dependent synthetase and ligase
AOR13_942	COG1028	Short-chain dehydrogenase reductase Sdr
AOR13_944	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOR13_944	COG0140	phosphoribosyl-ATP diphosphatase activity
AOR13_947	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOR13_948	COG0131	Imidazoleglycerol-phosphate dehydratase
AOR13_948	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AOR13_949	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOR13_950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOR13_951	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOR13_965	COG1199	ATP-dependent helicase activity
AOR13_966	COG1214	PFAM Peptidase M22, glycoprotease
AOR13_97	COG0733	neurotransmitter:sodium symporter activity
AOR13_970	COG2267	carboxylic ester hydrolase activity
AOR13_971	COG0318	PFAM AMP-dependent synthetase and ligase
AOR13_972	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AOR13_975	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOR13_976	COG2983	Belongs to the UPF0260 family
AOR13_977	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOR13_978	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AOR13_98	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOR13_980	COG2186	Transcriptional regulator
AOR13_987	COG4399	Belongs to the UPF0754 family
AOR13_988	COG1309	transcriptional regulator
AOR13_989	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOR13_994	COG1902	pentaerythritol trinitrate reductase activity
AOR13_994	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOR13_998	COG0789	Transcriptional regulator