locus-tag	class	description
AVL57_00070	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_00075	COG1917	Cupin 2, conserved barrel domain protein
AVL57_00075	COG4977	sequence-specific DNA binding
AVL57_00085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVL57_00100	COG0463	Glycosyl transferase, family 2
AVL57_00105	COG2194	sulfuric ester hydrolase activity
AVL57_00110	COG2194	sulfuric ester hydrolase activity
AVL57_00120	COG3306	glycosyltransferase involved in LPS biosynthesis
AVL57_00125	COG0463	Glycosyl transferase, family 2
AVL57_00135	COG5002	protein histidine kinase activity
AVL57_00140	COG0745	RESPONSE REGULATOR receiver
AVL57_00245	COG5642	Protein of unknown function (DUF2384)
AVL57_00295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL57_00375	COG1136	(ABC) transporter
AVL57_00380	COG0577	efflux transmembrane transporter activity
AVL57_00380	COG1136	(ABC) transporter
AVL57_00395	COG4152	abc transporter atp-binding protein
AVL57_00510	COG2801	Transposase and inactivated derivatives
AVL57_00515	COG2826	transposase and inactivated derivatives, IS30 family
AVL57_00530	COG0745	RESPONSE REGULATOR receiver
AVL57_00555	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL57_00580	COG0789	Transcriptional regulator
AVL57_00585	COG2217	Heavy metal translocating P-type atpase
AVL57_00630	COG2801	Transposase and inactivated derivatives
AVL57_00645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVL57_00690	COG2132	Multicopper oxidase
AVL57_00725	COG0776	regulation of translation
AVL57_00745	COG5433	transposase activity
AVL57_00855	COG0210	DNA helicase
AVL57_00890	COG4680	protein conserved in bacteria
AVL57_00930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL57_00975	COG3706	GGDEF domain
AVL57_00975	COG0745	RESPONSE REGULATOR receiver
AVL57_01005	COG3209	COG3209 Rhs family protein
AVL57_01110	COG1192	Involved in chromosome partitioning
AVL57_01230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVL57_01235	COG0187	DNA topoisomerase II activity
AVL57_01260	COG2818	Glycosylase
AVL57_01270	COG3078	GTPase activator activity
AVL57_01285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVL57_01285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVL57_01290	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AVL57_01295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AVL57_01300	COG0569	domain protein
AVL57_01305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVL57_01305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVL57_01325	COG0758	DNA mediated transformation
AVL57_01340	COG0009	L-threonylcarbamoyladenylate synthase
AVL57_01345	COG0408	coproporphyrinogen oxidase activity
AVL57_01350	COG3047	cAMP biosynthetic process
AVL57_01365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AVL57_01420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVL57_01440	COG2234	aminopeptidase activity
AVL57_01455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVL57_01480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL57_01520	COG3642	lipopolysaccharide core region biosynthetic process
AVL57_01525	COG0859	PFAM glycosyl transferase family 9
AVL57_01545	COG0156	8-amino-7-oxononanoate synthase activity
AVL57_01555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVL57_01560	COG0705	Rhomboid family
AVL57_01570	COG3161	chorismate lyase activity
AVL57_01575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVL57_01580	COG2960	long-chain fatty acid transporting porin activity
AVL57_01585	COG0210	DNA helicase
AVL57_01605	COG0653	protein targeting
AVL57_01635	COG0326	Molecular chaperone. Has ATPase activity
AVL57_01645	COG0556	nucleotide-excision repair
AVL57_01650	COG1620	l-lactate permease
AVL57_01670	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL57_01670	COG1902	pentaerythritol trinitrate reductase activity
AVL57_01690	COG4638	Rieske (2fe-2S)
AVL57_01700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVL57_01700	COG1017	nitric oxide dioxygenase activity
AVL57_01705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVL57_01745	COG1760	l-serine dehydratase
AVL57_01750	COG0583	DNA-binding transcription factor activity
AVL57_01765	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_01770	COG4948	Mandelate Racemase Muconate Lactonizing
AVL57_01780	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_01785	COG4771	TonB-dependent receptor
AVL57_01790	COG0457	Tetratricopeptide repeat
AVL57_01795	COG4999	Histidine kinase
AVL57_01795	COG3850	Histidine kinase
AVL57_01795	COG3437	response regulator, receiver
AVL57_01795	COG2205	protein histidine kinase activity
AVL57_01800	COG4773	Receptor
AVL57_01805	COG0583	DNA-binding transcription factor activity
AVL57_01820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL57_01825	COG0842	Transport permease protein
AVL57_01825	COG1129	ABC transporter
AVL57_01830	COG0842	Transport permease protein
AVL57_01840	COG1960	acyl-CoA dehydrogenase activity
AVL57_01845	COG0583	DNA-binding transcription factor activity
AVL57_01860	COG3106	COG3106 Predicted ATPase
AVL57_01880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVL57_01895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVL57_01910	COG4771	TonB-dependent receptor
AVL57_01915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVL57_01925	COG0778	Nitroreductase
AVL57_01925	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AVL57_01940	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AVL57_01945	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AVL57_01950	COG1309	transcriptional regulator
AVL57_01975	COG1953	Uracil, thiamine, allantoin
AVL57_01985	COG3071	HemY protein
AVL57_01990	COG2959	enzyme of heme biosynthesis
AVL57_02000	COG0181	hydroxymethylbilane synthase activity
AVL57_02005	COG3706	GGDEF domain
AVL57_02005	COG0745	RESPONSE REGULATOR receiver
AVL57_02015	COG0194	GDP metabolic process
AVL57_02025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVL57_02035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVL57_02040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVL57_02050	COG0678	peroxiredoxin activity
AVL57_02050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL57_02070	COG1178	ABC-type Fe3 transport system permease component
AVL57_02075	COG3842	ATPase activity
AVL57_02080	COG2081	HI0933 family
AVL57_02085	COG0668	transmembrane transport
AVL57_02110	COG5002	protein histidine kinase activity
AVL57_02110	COG5001	Diguanylate cyclase
AVL57_02110	COG3447	MASE1 domain protein
AVL57_02120	COG0583	DNA-binding transcription factor activity
AVL57_02130	COG2076	Multidrug Resistance protein
AVL57_02145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL57_02150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL57_02160	COG0427	acetyl-CoA hydrolase
AVL57_02165	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVL57_02175	COG0840	transmembrane signaling receptor activity
AVL57_02185	COG3064	Membrane
AVL57_02190	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVL57_02195	COG5001	Diguanylate cyclase
AVL57_02195	COG5002	protein histidine kinase activity
AVL57_02205	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVL57_02215	COG0514	ATP-dependent DNA helicase (RecQ)
AVL57_02220	COG2050	protein possibly involved in aromatic compounds catabolism
AVL57_02225	COG2239	Acts as a magnesium transporter
AVL57_02235	COG3706	GGDEF domain
AVL57_02235	COG0745	RESPONSE REGULATOR receiver
AVL57_02250	COG1011	Hydrolase
AVL57_02265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVL57_02270	COG0019	diaminopimelate decarboxylase activity
AVL57_02300	COG0163	prenyltransferase activity
AVL57_02305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVL57_02315	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVL57_02340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVL57_02345	COG2814	Major facilitator Superfamily
AVL57_02350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL57_02370	COG1085	galactose-1-phosphate uridylyltransferase
AVL57_02375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AVL57_02385	COG0629	single-stranded DNA binding
AVL57_02425	COG3710	Transcriptional regulator
AVL57_02435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVL57_02455	COG4615	Cyclic peptide transporter
AVL57_02470	COG0745	RESPONSE REGULATOR receiver
AVL57_02480	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL57_02510	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL57_02535	COG1349	DNA-binding transcription factor activity
AVL57_02575	COG3267	Type II secretory pathway component ExeA
AVL57_02575	COG3409	Peptidoglycan-binding domain 1 protein
AVL57_02585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL57_02590	COG1459	type II secretion system
AVL57_02630	COG1077	Cell shape determining protein MreB Mrl
AVL57_02635	COG1792	Involved in formation and maintenance of cell shape
AVL57_02640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AVL57_02650	COG1530	ribonuclease E activity
AVL57_02660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL57_02665	COG0312	modulator of DNA gyrase
AVL57_02675	COG3028	Belongs to the UPF0307 family
AVL57_02680	COG0312	modulator of DNA gyrase
AVL57_02695	COG0745	RESPONSE REGULATOR receiver
AVL57_02700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL57_02700	COG4191	Histidine kinase
AVL57_02705	COG0297	glycogen (starch) synthase activity
AVL57_02715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVL57_02725	COG1194	a g-specific adenine glycosylase
AVL57_02780	COG0745	RESPONSE REGULATOR receiver
AVL57_02785	COG2198	Histidine kinase
AVL57_02785	COG0643	Histidine kinase
AVL57_02790	COG0835	chemotaxis
AVL57_02805	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVL57_02810	COG2201	protein-glutamate methylesterase activity
AVL57_02825	COG0501	Belongs to the peptidase M48B family
AVL57_02890	COG1609	Transcriptional regulator
AVL57_02895	COG0673	inositol 2-dehydrogenase activity
AVL57_02905	COG2211	Major facilitator Superfamily
AVL57_02955	COG1454	alcohol dehydrogenase
AVL57_02980	COG0051	transcription antitermination factor activity, RNA binding
AVL57_02995	COG0089	rRNA binding
AVL57_03005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVL57_03015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVL57_03030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVL57_03035	COG0438	transferase activity, transferring glycosyl groups
AVL57_03040	COG0859	PFAM glycosyl transferase family 9
AVL57_03045	COG1519	Transferase
AVL57_03080	COG0788	formyltetrahydrofolate deformylase activity
AVL57_03090	COG1643	Atp-dependent helicase
AVL57_03095	COG2951	lytic endotransglycosylase activity
AVL57_03105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVL57_03115	COG2354	Protein conserved in bacteria
AVL57_03140	COG0004	ammonium transporteR
AVL57_03145	COG0405	Gamma-glutamyltransferase
AVL57_03150	COG2837	iron assimilation
AVL57_03165	COG0540	Belongs to the ATCase OTCase family
AVL57_03190	COG2205	protein histidine kinase activity
AVL57_03190	COG0784	Response regulator, receiver
AVL57_03190	COG5002	protein histidine kinase activity
AVL57_03215	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_03225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVL57_03235	COG0512	Glutamine amidotransferase of anthranilate synthase
AVL57_03240	COG0180	Tryptophanyl-tRNA synthetase
AVL57_03245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AVL57_03265	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AVL57_03275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVL57_03310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVL57_03315	COG0281	malic enzyme
AVL57_03320	COG0625	glutathione transferase activity
AVL57_03355	COG5001	Diguanylate cyclase
AVL57_03355	COG3300	MHYT domain
AVL57_03360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AVL57_03360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVL57_03370	COG0137	argininosuccinate synthase activity
AVL57_03375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVL57_03390	COG1803	Methylglyoxal synthase
AVL57_03400	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVL57_03415	COG0745	RESPONSE REGULATOR receiver
AVL57_03420	COG2205	protein histidine kinase activity
AVL57_03425	COG2267	carboxylic ester hydrolase activity
AVL57_03430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVL57_03445	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL57_03455	COG4942	peptidase
AVL57_03465	COG2861	carbohydrate metabolic process
AVL57_03475	COG0584	glycerophosphoryl diester phosphodiesterase
AVL57_03490	COG1162	GTPase activity
AVL57_03495	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AVL57_03515	COG0457	Tetratricopeptide repeat
AVL57_03530	COG0028	Belongs to the TPP enzyme family
AVL57_03550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVL57_03555	COG0805	protein transport
AVL57_03570	COG3706	GGDEF domain
AVL57_03580	COG0248	Ppx GppA phosphatase
AVL57_03585	COG0513	Belongs to the DEAD box helicase family
AVL57_03590	COG3118	belongs to the thioredoxin family
AVL57_03595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVL57_03605	COG0784	Response regulator, receiver
AVL57_03605	COG2205	protein histidine kinase activity
AVL57_03610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AVL57_03620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVL57_03635	COG0783	Belongs to the Dps family
AVL57_03640	COG2133	pyrroloquinoline quinone binding
AVL57_03650	COG3118	belongs to the thioredoxin family
AVL57_03660	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AVL57_03670	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_03690	COG1757	Na H antiporter
AVL57_03710	COG3876	Protein conserved in bacteria
AVL57_03715	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AVL57_03735	COG0346	lactoylglutathione lyase activity
AVL57_03800	COG4115	mRNA cleavage
AVL57_03805	COG2161	toxin-antitoxin pair type II binding
AVL57_03920	COG0183	Belongs to the thiolase family
AVL57_03925	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL57_03925	COG1024	Enoyl-CoA hydratase
AVL57_03935	COG0006	proline dipeptidase activity
AVL57_03945	COG0142	geranyltranstransferase activity
AVL57_04005	COG1238	metal cluster binding
AVL57_04015	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVL57_04020	COG0585	pseudouridine synthase activity
AVL57_04035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AVL57_04045	COG0840	transmembrane signaling receptor activity
AVL57_04050	COG0506	proline dehydrogenase activity
AVL57_04050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVL57_04050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVL57_04065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL57_04075	COG2770	Histidine kinase
AVL57_04075	COG2205	protein histidine kinase activity
AVL57_04080	COG4991	sh3 domain protein
AVL57_04085	COG3025	triphosphatase activity
AVL57_04100	COG0494	nUDIX hydrolase
AVL57_04105	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AVL57_04110	COG0730	response to heat
AVL57_04115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVL57_04120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVL57_04125	COG2201	protein-glutamate methylesterase activity
AVL57_04130	COG3706	GGDEF domain
AVL57_04135	COG0784	Response regulator, receiver
AVL57_04135	COG5002	protein histidine kinase activity
AVL57_04155	COG0564	pseudouridine synthase activity
AVL57_04165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AVL57_04175	COG1802	Transcriptional regulator
AVL57_04180	COG3119	arylsulfatase activity
AVL57_04185	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_04190	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_04195	COG1063	alcohol dehydrogenase
AVL57_04200	COG4948	Mandelate Racemase Muconate Lactonizing
AVL57_04205	COG2814	Major facilitator Superfamily
AVL57_04225	COG2124	cytochrome p450
AVL57_04325	COG3119	arylsulfatase activity
AVL57_04360	COG3119	arylsulfatase activity
AVL57_04375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVL57_04375	COG1648	precorrin-2 dehydrogenase activity
AVL57_04395	COG1538	Outer membrane efflux protein
AVL57_04400	COG0494	nUDIX hydrolase
AVL57_04415	COG3150	esterase
AVL57_04430	COG4251	negative regulation of phosphorylation
AVL57_04435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL57_04455	COG1509	lysine 2,3-aminomutase activity
AVL57_04485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL57_04500	COG0271	Belongs to the BolA IbaG family
AVL57_04505	COG0671	phosphoesterase, PA-phosphatase related
AVL57_04515	COG3707	response regulator
AVL57_04525	COG0659	secondary active sulfate transmembrane transporter activity
AVL57_04530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVL57_04535	COG2146	nitrite reductase [NAD(P)H] activity
AVL57_04540	COG0243	molybdopterin cofactor binding
AVL57_04545	COG1648	precorrin-2 dehydrogenase activity
AVL57_04545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVL57_04560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVL57_04560	COG1116	anion transmembrane transporter activity
AVL57_04565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVL57_04570	COG1116	anion transmembrane transporter activity
AVL57_04585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVL57_04590	COG4206	TonB-dependent receptor
AVL57_04595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AVL57_04600	COG0348	domain, Protein
AVL57_04615	COG1960	acyl-CoA dehydrogenase activity
AVL57_04620	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_04640	COG4948	Mandelate Racemase Muconate Lactonizing
AVL57_04655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL57_04660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL57_04680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVL57_04685	COG0358	DNA primase activity
AVL57_04690	COG1610	YqeY-like protein
AVL57_04710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVL57_04715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVL57_04730	COG0537	adenosine 5'-monophosphoramidase activity
AVL57_04745	COG3135	benzoate transporter
AVL57_04750	COG1396	sequence-specific DNA binding
AVL57_04755	COG2974	May be involved in recombination
AVL57_04760	COG4191	Histidine kinase
AVL57_04760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL57_04765	COG0745	RESPONSE REGULATOR receiver
AVL57_04770	COG5002	protein histidine kinase activity
AVL57_04800	COG0811	peptide transport
AVL57_04805	COG0811	peptide transport
AVL57_04810	COG0848	biopolymer transport protein
AVL57_04815	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AVL57_04825	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AVL57_04830	COG3437	response regulator, receiver
AVL57_04840	COG0318	PFAM AMP-dependent synthetase and ligase
AVL57_04850	COG2133	pyrroloquinoline quinone binding
AVL57_04855	COG1049	propionate catabolic process, 2-methylcitrate cycle
AVL57_04875	COG0527	aspartate kinase activity
AVL57_04880	COG0840	transmembrane signaling receptor activity
AVL57_04885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVL57_04895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVL57_04900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVL57_04905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL57_04910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVL57_04915	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AVL57_04925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVL57_04945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVL57_04955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVL57_04960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AVL57_04965	COG3956	TIGRFAM MazG family protein
AVL57_04985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVL57_04990	COG1595	DNA-templated transcription, initiation
AVL57_05000	COG4206	TonB-dependent receptor
AVL57_05010	COG1473	amidohydrolase
AVL57_05015	COG0723	plastoquinol--plastocyanin reductase activity
AVL57_05020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVL57_05025	COG2857	Cytochrome c1
AVL57_05030	COG0625	glutathione transferase activity
AVL57_05035	COG2969	positive regulation of protein catabolic process
AVL57_05040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL57_05040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL57_05045	COG3708	Transcriptional regulator
AVL57_05045	COG2207	Transcriptional regulator
AVL57_05055	COG2239	Acts as a magnesium transporter
AVL57_05060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVL57_05070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVL57_05085	COG1137	ATPase activity
AVL57_05100	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AVL57_05115	COG1127	ABC transporter
AVL57_05120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVL57_05125	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVL57_05130	COG2854	intermembrane phospholipid transfer
AVL57_05140	COG5007	Belongs to the BolA IbaG family
AVL57_05150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVL57_05155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVL57_05165	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVL57_05180	COG2207	Transcriptional regulator
AVL57_05195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL57_05210	COG5001	Diguanylate cyclase
AVL57_05210	COG3300	MHYT domain
AVL57_05215	COG0784	Response regulator, receiver
AVL57_05215	COG2205	protein histidine kinase activity
AVL57_05225	COG2207	Transcriptional regulator
AVL57_05230	COG1979	alcohol dehydrogenase
AVL57_05255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AVL57_05265	COG0126	phosphoglycerate kinase activity
AVL57_05270	COG3588	fructose-bisphosphate aldolase
AVL57_05275	COG0823	Involved in the tonB-independent uptake of proteins
AVL57_05275	COG1506	peptidase
AVL57_05275	COG4946	Tricorn protease homolog
AVL57_05280	COG0248	Ppx GppA phosphatase
AVL57_05285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVL57_05295	COG0573	inorganic phosphate transmembrane transporter activity
AVL57_05300	COG0581	inorganic phosphate transmembrane transporter activity
AVL57_05305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVL57_05315	COG0306	phosphate transporter
AVL57_05325	COG0583	DNA-binding transcription factor activity
AVL57_05350	COG1272	protein, Hemolysin III
AVL57_05370	COG0477	Major facilitator Superfamily
AVL57_05375	COG1609	Transcriptional regulator
AVL57_05375	COG2207	Transcriptional regulator
AVL57_05380	COG1070	Carbohydrate kinase
AVL57_05385	COG2115	Belongs to the xylose isomerase family
AVL57_05390	COG4447	cellulose binding
AVL57_05390	COG5520	Belongs to the glycosyl hydrolase 30 family
AVL57_05390	COG3291	Pkd domain containing protein
AVL57_05395	COG2207	Transcriptional regulator
AVL57_05410	COG1472	Belongs to the glycosyl hydrolase 3 family
AVL57_05415	COG1846	Transcriptional regulator
AVL57_05420	COG1764	response to oxidative stress
AVL57_05435	COG1739	Uncharacterized protein family UPF0029
AVL57_05445	COG0420	3'-5' exonuclease activity
AVL57_05450	COG0419	ATPase involved in DNA repair
AVL57_05455	COG3706	GGDEF domain
AVL57_05465	COG2971	BadF BadG BcrA BcrD
AVL57_05470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AVL57_05475	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVL57_05480	COG0488	(ABC) transporter
AVL57_05515	COG4667	esterase of the alpha-beta hydrolase superfamily
AVL57_05615	COG1346	cytolysis
AVL57_05645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVL57_05655	COG0513	Belongs to the DEAD box helicase family
AVL57_05665	COG3409	Peptidoglycan-binding domain 1 protein
AVL57_05665	COG3267	Type II secretory pathway component ExeA
AVL57_05675	COG3437	response regulator, receiver
AVL57_05675	COG0784	Response regulator, receiver
AVL57_05680	COG0066	3-isopropylmalate dehydratase activity
AVL57_05690	COG0473	3-isopropylmalate dehydrogenase activity
AVL57_05695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVL57_05725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVL57_05740	COG4555	ABC transporter
AVL57_05745	COG1668	transmembrane transport
AVL57_05765	COG4133	protoheme IX ABC transporter activity
AVL57_05770	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL57_05775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL57_05780	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVL57_05790	COG1138	Cytochrome C-type biogenesis protein
AVL57_05795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVL57_05810	COG2853	Lipoprotein
AVL57_05815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVL57_05825	COG3104	oligopeptide transport
AVL57_05840	COG1682	transport, permease protein
AVL57_05870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVL57_05875	COG1555	photosystem II stabilization
AVL57_05875	COG1596	polysaccharide export
AVL57_05880	COG0473	3-isopropylmalate dehydrogenase activity
AVL57_05895	COG1611	Belongs to the LOG family
AVL57_05900	COG3706	GGDEF domain
AVL57_05900	COG0745	RESPONSE REGULATOR receiver
AVL57_05905	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVL57_05905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVL57_05975	COG0564	pseudouridine synthase activity
AVL57_05995	COG0024	Methionine aminopeptidase
AVL57_06000	COG0052	Belongs to the universal ribosomal protein uS2 family
AVL57_06010	COG0528	UMP kinase activity
AVL57_06020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVL57_06025	COG0575	Belongs to the CDS family
AVL57_06030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVL57_06035	COG0750	zinc metalloprotease
AVL57_06050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVL57_06055	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVL57_06070	COG0587	DNA-directed DNA polymerase activity
AVL57_06075	COG0825	malonyl-CoA metabolic process
AVL57_06080	COG0037	tRNA processing
AVL57_06100	COG0590	tRNA wobble adenosine to inosine editing
AVL57_06110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVL57_06110	COG0047	phosphoribosylformylglycinamidine synthase activity
AVL57_06115	COG2840	Smr protein MutS2
AVL57_06135	COG0513	Belongs to the DEAD box helicase family
AVL57_06140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVL57_06145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AVL57_06150	COG0583	DNA-binding transcription factor activity
AVL57_06170	COG1760	l-serine dehydratase
AVL57_06175	COG0494	nUDIX hydrolase
AVL57_06180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVL57_06190	COG1322	Protein conserved in bacteria
AVL57_06195	COG1404	Belongs to the peptidase S8 family
AVL57_06200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVL57_06205	COG0022	dehydrogenase e1 component
AVL57_06210	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL57_06215	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVL57_06220	COG0515	serine threonine protein kinase
AVL57_06225	COG1946	Acyl-CoA thioesterase
AVL57_06235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVL57_06245	COG1956	GAF domain-containing protein
AVL57_06260	COG0793	Belongs to the peptidase S41A family
AVL57_06265	COG0733	neurotransmitter:sodium symporter activity
AVL57_06275	COG0308	aminopeptidase N
AVL57_06305	COG2902	Dehydrogenase
AVL57_06310	COG0167	dihydroorotate dehydrogenase activity
AVL57_06335	COG3130	regulation of translation
AVL57_06340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVL57_06350	COG0415	Belongs to the DNA photolyase family
AVL57_06355	COG0415	Belongs to the DNA photolyase family
AVL57_06360	COG3046	protein related to deoxyribodipyrimidine photolyase
AVL57_06385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AVL57_06390	COG0589	response to stress
AVL57_06400	COG0069	glutamate synthase activity
AVL57_06415	COG2193	ferroxidase activity
AVL57_06425	COG3278	Belongs to the heme-copper respiratory oxidase family
AVL57_06440	COG2010	Cytochrome c
AVL57_06465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVL57_06475	COG0037	tRNA processing
AVL57_06480	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVL57_06500	COG1280	lysine exporter protein (LysE YggA)
AVL57_06505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AVL57_06510	COG2897	thiosulfate sulfurtransferase activity
AVL57_06515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AVL57_06590	COG0582	viral genome integration into host DNA
AVL57_06615	COG0322	excinuclease ABC activity
AVL57_06620	COG2197	response regulator
AVL57_06625	COG1741	Belongs to the pirin family
AVL57_06635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AVL57_06665	COG0642	Histidine kinase
AVL57_06670	COG0745	RESPONSE REGULATOR receiver
AVL57_06695	COG0670	Belongs to the BI1 family
AVL57_06705	COG2923	Belongs to the DsrF TusC family
AVL57_06715	COG2920	part of a sulfur-relay system
AVL57_06720	COG0561	phosphatase activity
AVL57_06735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVL57_06740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVL57_06745	COG0531	amino acid
AVL57_06745	COG1674	ftsk spoiiie
AVL57_06755	COG0686	Belongs to the AlaDH PNT family
AVL57_06760	COG0284	orotidine-5'-phosphate decarboxylase activity
AVL57_06765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AVL57_06770	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AVL57_06780	COG0776	regulation of translation
AVL57_06785	COG0539	negative regulation of cytoplasmic translation
AVL57_06790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVL57_06795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVL57_06800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AVL57_06815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL57_06820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVL57_06825	COG0633	Ferredoxin
AVL57_06830	COG5002	protein histidine kinase activity
AVL57_06860	COG0789	Transcriptional regulator
AVL57_06905	COG3547	Transposase (IS116 IS110 IS902 family)
AVL57_06935	COG1131	(ABC) transporter
AVL57_06970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AVL57_06975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVL57_06985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVL57_06995	COG4783	chaperone-mediated protein folding
AVL57_07005	COG1393	Belongs to the ArsC family
AVL57_07040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVL57_07075	COG0572	uridine kinase
AVL57_07080	COG3769	mannosylglycerate metabolic process
AVL57_07085	COG1215	transferase activity, transferring glycosyl groups
AVL57_07095	COG0303	'Molybdopterin
AVL57_07100	COG0534	Mate efflux family protein
AVL57_07120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVL57_07130	COG0405	Gamma-glutamyltransferase
AVL57_07135	COG1024	Enoyl-CoA hydratase
AVL57_07170	COG1448	Aminotransferase
AVL57_07175	COG1671	Belongs to the UPF0178 family
AVL57_07180	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_07190	COG1960	acyl-CoA dehydrogenase activity
AVL57_07195	COG1917	Cupin 2, conserved barrel domain protein
AVL57_07195	COG2207	Transcriptional regulator
AVL57_07245	COG0596	Alpha beta hydrolase
AVL57_07255	COG0716	FMN binding
AVL57_07275	COG3265	gluconokinase activity
AVL57_07280	COG1609	Transcriptional regulator
AVL57_07290	COG1984	allophanate hydrolase subunit 2
AVL57_07300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVL57_07305	COG2996	Protein conserved in bacteria
AVL57_07310	COG1765	OsmC-like protein
AVL57_07315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL57_07340	COG0436	Aminotransferase
AVL57_07345	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVL57_07350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AVL57_07360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVL57_07370	COG1238	metal cluster binding
AVL57_07415	COG4628	conserved protein (DUF2132)
AVL57_07425	COG0454	-acetyltransferase
AVL57_07430	COG1119	ATPase activity
AVL57_07440	COG1185	polyribonucleotide nucleotidyltransferase activity
AVL57_07465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL57_07505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVL57_07510	COG0149	triose-phosphate isomerase activity
AVL57_07515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVL57_07520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVL57_07525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVL57_07530	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVL57_07535	COG1534	Rna-binding protein
AVL57_07545	COG1067	ATP-dependent peptidase activity
AVL57_07550	COG0495	leucyl-tRNA aminoacylation
AVL57_07560	COG1466	dna polymerase III delta subunit
AVL57_07565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVL57_07570	COG0799	negative regulation of ribosome biogenesis
AVL57_07575	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVL57_07580	COG0768	penicillin binding
AVL57_07585	COG0772	Belongs to the SEDS family
AVL57_07590	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVL57_07595	COG1686	Belongs to the peptidase S11 family
AVL57_07600	COG2921	Belongs to the UPF0250 family
AVL57_07605	COG0321	lipoyl(octanoyl) transferase activity
AVL57_07610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVL57_07620	COG0252	asparaginase activity
AVL57_07630	COG0778	Nitroreductase
AVL57_07645	COG0616	signal peptide processing
AVL57_07665	COG0492	ferredoxin-NADP+ reductase activity
AVL57_07670	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVL57_07675	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVL57_07680	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVL57_07685	COG0542	response to heat
AVL57_07690	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVL57_07695	COG1278	Cold shock
AVL57_07705	COG1187	pseudouridine synthase activity
AVL57_07710	COG0482	sulfurtransferase activity
AVL57_07715	COG2915	High frequency lysogenization protein hflD homolog
AVL57_07720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVL57_07730	COG2850	peptidyl-arginine hydroxylation
AVL57_07745	COG0247	lactate metabolic process
AVL57_07745	COG0277	FAD linked oxidase domain protein
AVL57_07750	COG3123	guanosine phosphorylase activity
AVL57_07755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVL57_07800	COG1695	Transcriptional regulator
AVL57_07815	COG1077	Cell shape determining protein MreB Mrl
AVL57_07840	COG3265	gluconokinase activity
AVL57_07850	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_07865	COG1609	Transcriptional regulator
AVL57_07870	COG0679	Auxin Efflux Carrier
AVL57_07890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVL57_07890	COG0574	Belongs to the PEP-utilizing enzyme family
AVL57_07910	COG1942	4-Oxalocrotonate Tautomerase
AVL57_07930	COG1714	RDD family
AVL57_07950	COG3706	GGDEF domain
AVL57_07950	COG0745	RESPONSE REGULATOR receiver
AVL57_07955	COG0702	epimerase
AVL57_07965	COG0084	hydrolase, TatD family'
AVL57_07970	COG0470	DNA polymerase III
AVL57_07980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVL57_07985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVL57_07990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVL57_07995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVL57_08010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVL57_08015	COG0416	fatty acid biosynthetic process
AVL57_08025	COG1399	metal-binding, possibly nucleic acid-binding protein
AVL57_08030	COG0424	maF-like protein
AVL57_08035	COG0546	phosphoglycolate phosphatase activity
AVL57_08045	COG1530	ribonuclease E activity
AVL57_08065	COG2153	protein acetylation
AVL57_08085	COG0625	glutathione transferase activity
AVL57_08100	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL57_08110	COG0583	DNA-binding transcription factor activity
AVL57_08120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVL57_08125	COG3724	N-succinylarginine dihydrolase activity
AVL57_08135	COG1301	dicarboxylic acid transport
AVL57_08140	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVL57_08145	COG1136	(ABC) transporter
AVL57_08150	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVL57_08180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVL57_08185	COG0328	RNA-DNA hybrid ribonuclease activity
AVL57_08210	COG1643	Atp-dependent helicase
AVL57_08250	COG3437	response regulator, receiver
AVL57_08250	COG4999	Histidine kinase
AVL57_08250	COG2205	protein histidine kinase activity
AVL57_08250	COG3850	Histidine kinase
AVL57_08255	COG2925	Exonuclease
AVL57_08270	COG0183	Belongs to the thiolase family
AVL57_08275	COG0789	Transcriptional regulator
AVL57_08280	COG1960	acyl-CoA dehydrogenase activity
AVL57_08285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVL57_08290	COG1024	Enoyl-CoA hydratase
AVL57_08325	COG1957	nucleoside hydrolase
AVL57_08340	COG2814	Major facilitator Superfamily
AVL57_08375	COG0708	Exodeoxyribonuclease III
AVL57_08390	COG4591	ABC-type transport system involved in lipoprotein release permease component
AVL57_08400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVL57_08410	COG2096	Adenosyltransferase
AVL57_08415	COG0471	metal ion transport
AVL57_08420	COG1472	Belongs to the glycosyl hydrolase 3 family
AVL57_08430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVL57_08445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL57_08445	COG0072	phenylalanine-tRNA ligase activity
AVL57_08485	COG2244	polysaccharide biosynthetic process
AVL57_08495	COG1215	transferase activity, transferring glycosyl groups
AVL57_08510	COG0438	transferase activity, transferring glycosyl groups
AVL57_08545	COG4464	protein tyrosine phosphatase activity
AVL57_08550	COG0489	protein tyrosine kinase activity
AVL57_08555	COG1596	polysaccharide export
AVL57_08565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVL57_08585	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVL57_08600	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_08640	COG0730	response to heat
AVL57_08645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AVL57_08660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL57_08665	COG2233	PERMEase
AVL57_08680	COG5002	protein histidine kinase activity
AVL57_08680	COG0784	Response regulator, receiver
AVL57_08685	COG0745	RESPONSE REGULATOR receiver
AVL57_08685	COG3706	GGDEF domain
AVL57_08690	COG3300	MHYT domain
AVL57_08690	COG5001	Diguanylate cyclase
AVL57_08700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVL57_08705	COG2252	PERMEase
AVL57_08720	COG1309	transcriptional regulator
AVL57_08730	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVL57_08745	COG2351	hydroxyisourate hydrolase activity
AVL57_08750	COG0402	S-adenosylhomocysteine deaminase activity
AVL57_08760	COG3447	MASE1 domain protein
AVL57_08760	COG5001	Diguanylate cyclase
AVL57_08760	COG5002	protein histidine kinase activity
AVL57_08780	COG3706	GGDEF domain
AVL57_08795	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AVL57_08820	COG2211	Major facilitator Superfamily
AVL57_08820	COG2190	(PTS) system
AVL57_08825	COG1393	Belongs to the ArsC family
AVL57_08855	COG2988	succinylglutamate desuccinylase activity
AVL57_08865	COG0058	SHG alpha-glucan phosphorylase activity
AVL57_08870	COG0033	Phosphoglucomutase
AVL57_08875	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AVL57_08880	COG0714	Associated with various cellular activities
AVL57_08895	COG2116	formate transmembrane transporter activity
AVL57_08900	COG2815	serine threonine protein kinase
AVL57_08900	COG0515	serine threonine protein kinase
AVL57_08905	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AVL57_08930	COG0583	DNA-binding transcription factor activity
AVL57_08945	COG3094	Invasion gene expression up-regulator, SirB
AVL57_08950	COG0784	Response regulator, receiver
AVL57_08950	COG3437	response regulator, receiver
AVL57_08955	COG2890	protein-(glutamine-N5) methyltransferase activity
AVL57_08965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AVL57_08970	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AVL57_08975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVL57_08985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVL57_08990	COG5001	Diguanylate cyclase
AVL57_08990	COG3300	MHYT domain
AVL57_09000	COG1064	alcohol dehydrogenase
AVL57_09015	COG0012	GTP binding
AVL57_09020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL57_09045	COG1115	amino acid carrier protein
AVL57_09050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVL57_09065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL57_09075	COG1702	phosphate starvation-inducible protein PhoH
AVL57_09085	COG4535	Mg2 and Co2 transporter CorC
AVL57_09090	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVL57_09095	COG0280	phosphate acetyltransferase
AVL57_09095	COG0857	belongs to the CobB CobQ family
AVL57_09100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AVL57_09105	COG0071	Belongs to the small heat shock protein (HSP20) family
AVL57_09130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVL57_09135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVL57_09140	COG0505	Belongs to the CarA family
AVL57_09145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVL57_09160	COG5001	Diguanylate cyclase
AVL57_09160	COG4251	negative regulation of phosphorylation
AVL57_09160	COG3706	GGDEF domain
AVL57_09160	COG2203	Gaf domain
AVL57_09165	COG3909	cytochrome
AVL57_09170	COG0484	heat shock protein binding
AVL57_09180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVL57_09185	COG0784	Response regulator, receiver
AVL57_09185	COG2205	protein histidine kinase activity
AVL57_09195	COG4771	TonB-dependent receptor
AVL57_09200	COG2610	gluconate transmembrane transporter activity
AVL57_09205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVL57_09215	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_09225	COG0497	DNA recombination
AVL57_09230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL57_09235	COG0500	methyltransferase
AVL57_09240	COG2733	membrane
AVL57_09255	COG0110	maltose O-acetyltransferase activity
AVL57_09260	COG0656	L-ascorbic acid biosynthetic process
AVL57_09275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVL57_09280	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVL57_09285	COG0009	L-threonylcarbamoyladenylate synthase
AVL57_09290	COG0613	PHP domain protein
AVL57_09295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVL57_09305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVL57_09310	COG0135	phosphoribosylanthranilate isomerase activity
AVL57_09310	COG0134	indole-3-glycerol-phosphate synthase activity
AVL57_09320	COG0159	tryptophan synthase activity
AVL57_09325	COG2350	Protein conserved in bacteria
AVL57_09340	COG0745	RESPONSE REGULATOR receiver
AVL57_09345	COG2205	protein histidine kinase activity
AVL57_09350	COG0628	permease
AVL57_09355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AVL57_09360	COG1090	epimerase
AVL57_09365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVL57_09370	COG4181	ATPase activity
AVL57_09390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL57_09425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVL57_09445	COG0745	RESPONSE REGULATOR receiver
AVL57_09455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVL57_09460	COG5265	(ABC) transporter
AVL57_09475	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AVL57_09485	COG4139	cobalamin transport
AVL57_09490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AVL57_09505	COG1073	alpha beta
AVL57_09505	COG2226	methyltransferase
AVL57_09510	COG0156	8-amino-7-oxononanoate synthase activity
AVL57_09535	COG0456	acetyltransferase
AVL57_09540	COG0189	ligase activity
AVL57_09555	COG0017	Asparaginyl-tRNA synthetase
AVL57_09565	COG2995	paraquat-inducible protein a
AVL57_09570	COG3008	intermembrane lipid transfer
AVL57_09570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVL57_09580	COG3706	GGDEF domain
AVL57_09600	COG0583	DNA-binding transcription factor activity
AVL57_09605	COG1309	transcriptional regulator
AVL57_09615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVL57_09620	COG0517	IMP dehydrogenase activity
AVL57_09635	COG0583	DNA-binding transcription factor activity
AVL57_09640	COG3038	cytochrome b561
AVL57_09675	COG2271	Major facilitator Superfamily
AVL57_09680	COG0784	Response regulator, receiver
AVL57_09680	COG2205	protein histidine kinase activity
AVL57_09720	COG0024	Methionine aminopeptidase
AVL57_09730	COG0745	RESPONSE REGULATOR receiver
AVL57_09730	COG3706	GGDEF domain
AVL57_09755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVL57_09775	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AVL57_09780	COG2885	chlorophyll binding
AVL57_09785	COG0823	Involved in the tonB-independent uptake of proteins
AVL57_09800	COG0811	peptide transport
AVL57_09805	COG0824	Thioesterase
AVL57_09810	COG2255	four-way junction helicase activity
AVL57_09825	COG0494	nUDIX hydrolase
AVL57_09830	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVL57_09845	COG2204	response regulator
AVL57_09855	COG2205	protein histidine kinase activity
AVL57_09875	COG0745	RESPONSE REGULATOR receiver
AVL57_09875	COG3706	GGDEF domain
AVL57_09885	COG0023	Translation Initiation Factor
AVL57_09890	COG0745	RESPONSE REGULATOR receiver
AVL57_09895	COG1605	Chorismate mutase
AVL57_09895	COG0077	Prephenate dehydratase
AVL57_09900	COG0840	transmembrane signaling receptor activity
AVL57_09905	COG1605	Chorismate mutase
AVL57_09905	COG0287	Prephenate dehydrogenase
AVL57_09910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AVL57_09915	COG2860	membrane
AVL57_09930	COG0335	large ribosomal subunit rRNA binding
AVL57_09935	COG0336	Belongs to the RNA methyltransferase TrmD family
AVL57_09940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVL57_09945	COG0228	four-way junction DNA binding
AVL57_09965	COG1132	(ABC) transporter
AVL57_09970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL57_09980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVL57_10010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVL57_10015	COG4137	Cytochrome C assembly protein
AVL57_10020	COG4536	flavin adenine dinucleotide binding
AVL57_10030	COG2062	phosphohistidine phosphatase, SixA
AVL57_10035	COG1025	Belongs to the peptidase M16 family
AVL57_10050	COG1024	Enoyl-CoA hydratase
AVL57_10050	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL57_10060	COG0714	Associated with various cellular activities
AVL57_10080	COG2304	oxidoreductase activity
AVL57_10105	COG3706	GGDEF domain
AVL57_10110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL57_10115	COG0175	sulfate reduction
AVL57_10120	COG0529	Catalyzes the synthesis of activated sulfate
AVL57_10135	COG3273	potassium ion transport
AVL57_10135	COG0471	metal ion transport
AVL57_10160	COG0367	asparagine synthase
AVL57_10170	COG0602	queuosine metabolic process
AVL57_10195	COG0556	nucleotide-excision repair
AVL57_10200	COG0534	Mate efflux family protein
AVL57_10215	COG4657	Part of a membrane complex involved in electron transport
AVL57_10220	COG2878	Part of a membrane complex involved in electron transport
AVL57_10225	COG4656	Part of a membrane complex involved in electron transport
AVL57_10230	COG4658	electron transport chain
AVL57_10240	COG4660	Part of a membrane complex involved in electron transport
AVL57_10245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AVL57_10270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVL57_10275	COG4946	Tricorn protease homolog
AVL57_10275	COG1506	peptidase
AVL57_10275	COG0823	Involved in the tonB-independent uptake of proteins
AVL57_10300	COG1278	Cold shock
AVL57_10305	COG0346	lactoylglutathione lyase activity
AVL57_10310	COG0584	glycerophosphoryl diester phosphodiesterase
AVL57_10315	COG2885	chlorophyll binding
AVL57_10320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AVL57_10325	COG0450	alkyl hydroperoxide reductase
AVL57_10350	COG4771	TonB-dependent receptor
AVL57_10355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVL57_10365	COG2766	serine protein kinase
AVL57_10370	COG2718	Belongs to the UPF0229 family
AVL57_10375	COG2719	SpoVR family
AVL57_10395	COG2890	protein-(glutamine-N5) methyltransferase activity
AVL57_10400	COG2840	Smr protein MutS2
AVL57_10425	COG1136	(ABC) transporter
AVL57_10450	COG0612	Peptidase, M16
AVL57_10460	COG0564	pseudouridine synthase activity
AVL57_10465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AVL57_10470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVL57_10495	COG2175	clavaminate synthase activity
AVL57_10525	COG0583	DNA-binding transcription factor activity
AVL57_10540	COG0456	acetyltransferase
AVL57_10595	COG0848	biopolymer transport protein
AVL57_10600	COG0811	peptide transport
AVL57_10605	COG0811	peptide transport
AVL57_10645	COG0457	Tetratricopeptide repeat
AVL57_10670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AVL57_10675	COG1522	sequence-specific DNA binding
AVL57_10680	COG0625	glutathione transferase activity
AVL57_10710	COG1842	Phage shock protein A
AVL57_10715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AVL57_10720	COG0747	negative chemotaxis
AVL57_10725	COG4168	peptide transport system, permease
AVL57_10730	COG4171	peptide transport system, permease
AVL57_10735	COG4172	Belongs to the ABC transporter superfamily
AVL57_10740	COG4172	Belongs to the ABC transporter superfamily
AVL57_10745	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AVL57_10760	COG1607	acyl-coa hydrolase
AVL57_10800	COG3590	peptidase
AVL57_10805	COG1309	transcriptional regulator
AVL57_10815	COG0659	secondary active sulfate transmembrane transporter activity
AVL57_10820	COG0288	reversible hydration of carbon dioxide
AVL57_10825	COG0583	DNA-binding transcription factor activity
AVL57_10830	COG0583	DNA-binding transcription factor activity
AVL57_10840	COG1410	methionine synthase
AVL57_10840	COG0646	methionine synthase
AVL57_10845	COG1410	methionine synthase
AVL57_10845	COG0646	methionine synthase
AVL57_10860	COG0835	chemotaxis
AVL57_10870	COG1192	Involved in chromosome partitioning
AVL57_10875	COG2201	protein-glutamate methylesterase activity
AVL57_10880	COG0643	Histidine kinase
AVL57_10880	COG2198	Histidine kinase
AVL57_10885	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AVL57_10900	COG0455	bacterial-type flagellum organization
AVL57_10910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVL57_10925	COG1987	bacterial-type flagellum assembly
AVL57_10975	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVL57_10980	COG1766	The M ring may be actively involved in energy transduction
AVL57_10990	COG2204	response regulator
AVL57_10995	COG3852	Histidine kinase
AVL57_11000	COG2204	response regulator
AVL57_11015	COG1083	cytidylyl-transferase
AVL57_11025	COG2089	acid synthase
AVL57_11040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVL57_11080	COG2089	acid synthase
AVL57_11085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AVL57_11090	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AVL57_11130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVL57_11135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVL57_11155	COG1256	bacterial-type flagellum assembly
AVL57_11160	COG3951	Flagellar rod assembly protein muramidase FlgJ
AVL57_11160	COG1705	Flagellar rod assembly protein muramidase FlgJ
AVL57_11175	COG4786	Flagellar basal body rod
AVL57_11180	COG4787	bacterial-type flagellum-dependent cell motility
AVL57_11185	COG1749	Flagellar hook protein flgE
AVL57_11190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVL57_11195	COG1558	bacterial-type flagellum-dependent cell motility
AVL57_11200	COG1815	bacterial-type flagellum-dependent cell motility
AVL57_11205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVL57_11210	COG0784	Response regulator, receiver
AVL57_11210	COG0835	chemotaxis
AVL57_11250	COG2197	response regulator
AVL57_11255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVL57_11260	COG2274	protein secretion by the type I secretion system
AVL57_11265	COG2885	chlorophyll binding
AVL57_11370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL57_11370	COG2205	protein histidine kinase activity
AVL57_11380	COG0205	6-phosphofructokinase activity
AVL57_11385	COG3279	Response regulator of the LytR AlgR family
AVL57_11390	COG3275	phosphorelay sensor kinase activity
AVL57_11420	COG3081	Nucleoid-associated protein
AVL57_11425	COG3082	Protein of unknown function (DUF1414)
AVL57_11430	COG3083	sulfuric ester hydrolase activity
AVL57_11440	COG2226	methyltransferase
AVL57_11445	COG1024	Enoyl-CoA hydratase
AVL57_11450	COG1960	acyl-CoA dehydrogenase activity
AVL57_11460	COG2084	Dehydrogenase
AVL57_11465	COG0386	Belongs to the glutathione peroxidase family
AVL57_11470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVL57_11475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVL57_11480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AVL57_11505	COG0616	signal peptide processing
AVL57_11515	COG2267	carboxylic ester hydrolase activity
AVL57_11520	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_11530	COG1609	Transcriptional regulator
AVL57_11545	COG0366	Alpha amylase catalytic
AVL57_11565	COG4667	esterase of the alpha-beta hydrolase superfamily
AVL57_11600	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL57_11605	COG0567	Dehydrogenase, E1 component
AVL57_11615	COG1053	succinate dehydrogenase
AVL57_11620	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AVL57_11625	COG2009	succinate dehydrogenase
AVL57_11645	COG0435	Glutathione S-transferase
AVL57_11650	COG0579	oxidoreductase
AVL57_11655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVL57_11695	COG1663	tetraacyldisaccharide 4'-kinase activity
AVL57_11700	COG1132	(ABC) transporter
AVL57_11715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVL57_11725	COG1196	nuclear chromosome segregation
AVL57_11745	COG0295	cytidine deaminase activity
AVL57_11770	COG0477	Major facilitator Superfamily
AVL57_11790	COG2318	DinB family
AVL57_11795	COG0457	Tetratricopeptide repeat
AVL57_11805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AVL57_11815	COG2914	Belongs to the UPF0125 (RnfH) family
AVL57_11820	COG2867	negative regulation of translational initiation
AVL57_11845	COG4771	TonB-dependent receptor
AVL57_11850	COG2814	Major facilitator Superfamily
AVL57_11880	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_11890	COG1595	DNA-templated transcription, initiation
AVL57_11920	COG0583	DNA-binding transcription factor activity
AVL57_11940	COG5001	Diguanylate cyclase
AVL57_11940	COG3300	MHYT domain
AVL57_11955	COG2203	Gaf domain
AVL57_11955	COG3706	GGDEF domain
AVL57_11955	COG5001	Diguanylate cyclase
AVL57_11955	COG4251	negative regulation of phosphorylation
AVL57_11970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVL57_11975	COG4136	ATPase activity
AVL57_11980	COG4135	transport system, permease component
AVL57_11985	COG4134	Bacterial extracellular solute-binding protein
AVL57_12000	COG4771	TonB-dependent receptor
AVL57_12015	COG1032	radical SAM domain protein
AVL57_12040	COG4774	siderophore transport
AVL57_12050	COG0450	alkyl hydroperoxide reductase
AVL57_12075	COG3153	acetyltransferase
AVL57_12075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL57_12085	COG0596	Alpha beta hydrolase
AVL57_12090	COG3706	GGDEF domain
AVL57_12100	COG4269	membrane
AVL57_12110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVL57_12125	COG0195	Participates in both transcription termination and antitermination
AVL57_12135	COG3437	response regulator, receiver
AVL57_12140	COG0784	Response regulator, receiver
AVL57_12140	COG2205	protein histidine kinase activity
AVL57_12140	COG2198	Histidine kinase
AVL57_12160	COG4771	TonB-dependent receptor
AVL57_12165	COG0668	transmembrane transport
AVL57_12185	COG0668	transmembrane transport
AVL57_12205	COG0246	Mannitol dehydrogenase
AVL57_12215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL57_12220	COG2390	Transcriptional regulator
AVL57_12235	COG0596	Alpha beta hydrolase
AVL57_12240	COG1960	acyl-CoA dehydrogenase activity
AVL57_12245	COG0183	Belongs to the thiolase family
AVL57_12250	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVL57_12250	COG1024	Enoyl-CoA hydratase
AVL57_12255	COG0596	Alpha beta hydrolase
AVL57_12285	COG1960	acyl-CoA dehydrogenase activity
AVL57_12295	COG4771	TonB-dependent receptor
AVL57_12315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVL57_12320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AVL57_12335	COG0314	molybdopterin synthase activity
AVL57_12340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AVL57_12345	COG0315	cyclic pyranopterin monophosphate synthase activity
AVL57_12350	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVL57_12355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AVL57_12550	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_12585	COG0436	Aminotransferase
AVL57_12590	COG3268	Saccharopine dehydrogenase
AVL57_12605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVL57_12620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVL57_12625	COG1074	ATP-dependent DNA helicase activity
AVL57_12630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AVL57_12640	COG1022	Amp-dependent synthetase and ligase
AVL57_12645	COG5001	Diguanylate cyclase
AVL57_12645	COG3300	MHYT domain
AVL57_12670	COG0583	DNA-binding transcription factor activity
AVL57_12690	COG0640	Transcriptional regulator
AVL57_12700	COG0583	DNA-binding transcription factor activity
AVL57_12710	COG2204	response regulator
AVL57_12720	COG4251	negative regulation of phosphorylation
AVL57_12725	COG0784	Response regulator, receiver
AVL57_12755	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVL57_12780	COG3139	Protein of unknown function (DUF1315)
AVL57_12790	COG1115	amino acid carrier protein
AVL57_12795	COG2866	Carboxypeptidase
AVL57_12815	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AVL57_12825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVL57_12830	COG1640	4-alpha-glucanotransferase
AVL57_12840	COG0676	glucose-6-phosphate 1-epimerase activity
AVL57_12845	COG0800	Aldolase
AVL57_12855	COG0129	dihydroxy-acid dehydratase activity
AVL57_12865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVL57_12870	COG1737	Transcriptional regulator
AVL57_12875	COG0469	pyruvate kinase activity
AVL57_12880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVL57_12925	COG2205	protein histidine kinase activity
AVL57_12930	COG0745	RESPONSE REGULATOR receiver
AVL57_12955	COG3665	Urea carboxylase-associated protein
AVL57_12965	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_12970	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AVL57_12995	COG2721	sulfolactate sulfo-lyase activity
AVL57_13000	COG1904	glucuronate isomerase
AVL57_13005	COG0246	Mannitol dehydrogenase
AVL57_13010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL57_13015	COG2755	lipolytic protein G-D-S-L family
AVL57_13025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVL57_13035	COG4677	pectinesterase activity
AVL57_13055	COG2356	endonuclease I
AVL57_13065	COG1024	Enoyl-CoA hydratase
AVL57_13085	COG1609	Transcriptional regulator
AVL57_13090	COG4948	Mandelate Racemase Muconate Lactonizing
AVL57_13095	COG0673	inositol 2-dehydrogenase activity
AVL57_13110	COG5001	Diguanylate cyclase
AVL57_13110	COG3300	MHYT domain
AVL57_13125	COG0746	molybdenum cofactor guanylyltransferase activity
AVL57_13135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVL57_13140	COG1764	response to oxidative stress
AVL57_13155	COG3706	GGDEF domain
AVL57_13165	COG0745	RESPONSE REGULATOR receiver
AVL57_13170	COG5002	protein histidine kinase activity
AVL57_13170	COG3850	Histidine kinase
AVL57_13200	COG1957	nucleoside hydrolase
AVL57_13205	COG0738	Major facilitator superfamily
AVL57_13230	COG0840	transmembrane signaling receptor activity
AVL57_13240	COG0753	catalase activity
AVL57_13250	COG0330	HflC and HflK could
AVL57_13270	COG0778	Nitroreductase
AVL57_13290	COG0471	metal ion transport
AVL57_13300	COG0489	protein tyrosine kinase activity
AVL57_13305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL57_13305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL57_13310	COG2226	methyltransferase
AVL57_13315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL57_13320	COG0741	lytic transglycosylase activity
AVL57_13320	COG1388	LysM domain
AVL57_13340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AVL57_13350	COG1785	Belongs to the alkaline phosphatase family
AVL57_13355	COG1785	Belongs to the alkaline phosphatase family
AVL57_13370	COG2268	Band 7 protein
AVL57_13390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVL57_13395	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVL57_13400	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVL57_13405	COG2080	2 iron, 2 sulfur cluster binding
AVL57_13415	COG0604	alcohol dehydrogenase
AVL57_13425	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AVL57_13440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVL57_13445	COG1286	toxin biosynthetic process
AVL57_13450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AVL57_13455	COG0285	dihydrofolate synthase activity
AVL57_13465	COG0101	tRNA pseudouridine synthase activity
AVL57_13480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL57_13500	COG3706	GGDEF domain
AVL57_13505	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVL57_13505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVL57_13535	COG3101	peptidyl-lysine hydroxylation
AVL57_13570	COG2207	Transcriptional regulator
AVL57_13575	COG1073	alpha beta
AVL57_13600	COG2826	transposase and inactivated derivatives, IS30 family
AVL57_13640	COG0789	Transcriptional regulator
AVL57_13665	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL57_13665	COG1902	pentaerythritol trinitrate reductase activity
AVL57_13690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVL57_13695	COG1309	transcriptional regulator
AVL57_13700	COG4399	Belongs to the UPF0754 family
AVL57_13735	COG2186	Transcriptional regulator
AVL57_13745	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AVL57_13750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVL57_13755	COG2983	Belongs to the UPF0260 family
AVL57_13760	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVL57_13775	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AVL57_13780	COG0318	PFAM AMP-dependent synthetase and ligase
AVL57_13785	COG2267	carboxylic ester hydrolase activity
AVL57_13800	COG1214	PFAM Peptidase M22, glycoprotease
AVL57_13805	COG1199	ATP-dependent helicase activity
AVL57_13860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVL57_13865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVL57_13870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVL57_13875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVL57_13875	COG0131	Imidazoleglycerol-phosphate dehydratase
AVL57_13880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVL57_13895	COG0140	phosphoribosyl-ATP diphosphatase activity
AVL57_13895	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVL57_13905	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_13915	COG1022	Amp-dependent synthetase and ligase
AVL57_13935	COG0463	Glycosyl transferase, family 2
AVL57_13955	COG0642	Histidine kinase
AVL57_13960	COG0745	RESPONSE REGULATOR receiver
AVL57_13965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL57_13990	COG0326	Molecular chaperone. Has ATPase activity
AVL57_13995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVL57_14020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVL57_14025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVL57_14035	COG3220	belongs to the UPF0276 family
AVL57_14045	COG4249	Peptidase C14 caspase catalytic subunit p20
AVL57_14045	COG2319	Wd-40 repeat
AVL57_14060	COG2203	Gaf domain
AVL57_14060	COG5001	Diguanylate cyclase
AVL57_14060	COG3706	GGDEF domain
AVL57_14060	COG4251	negative regulation of phosphorylation
AVL57_14095	COG1183	phosphatidylcholine synthase activity
AVL57_14115	COG0542	response to heat
AVL57_14125	COG0564	pseudouridine synthase activity
AVL57_14140	COG1595	DNA-templated transcription, initiation
AVL57_14155	COG4221	oxidoreductase activity
AVL57_14170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVL57_14180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVL57_14185	COG1722	exodeoxyribonuclease VII activity
AVL57_14190	COG0142	geranyltranstransferase activity
AVL57_14200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AVL57_14205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AVL57_14215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVL57_14230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVL57_14230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVL57_14245	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVL57_14250	COG0488	(ABC) transporter
AVL57_14260	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AVL57_14270	COG0560	Phosphoserine phosphatase
AVL57_14280	COG0084	hydrolase, TatD family'
AVL57_14300	COG0681	Belongs to the peptidase S26 family
AVL57_14325	COG1595	DNA-templated transcription, initiation
AVL57_14330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVL57_14345	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AVL57_14365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AVL57_14425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVL57_14430	COG1047	Peptidyl-prolyl cis-trans
AVL57_14440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVL57_14445	COG0196	riboflavin kinase activity
AVL57_14450	COG0728	peptidoglycan biosynthetic process
AVL57_14455	COG0268	Binds directly to 16S ribosomal RNA
AVL57_14470	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_14475	COG0385	Bile acid
AVL57_14500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL57_14505	COG0776	regulation of translation
AVL57_14510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVL57_14515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVL57_14520	COG0740	serine-type endopeptidase activity
AVL57_14525	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVL57_14565	COG1720	tRNA m6t6A37 methyltransferase activity
AVL57_14580	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AVL57_14585	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVL57_14605	COG0516	GMP reductase activity
AVL57_14605	COG0517	IMP dehydrogenase activity
AVL57_14610	COG1570	exodeoxyribonuclease VII activity
AVL57_14625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVL57_14630	COG2976	Protein conserved in bacteria
AVL57_14655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVL57_14665	COG2166	iron-sulfur cluster assembly
AVL57_14680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVL57_14685	COG0719	Fe-S assembly protein
AVL57_14690	COG0396	ATPase activity
AVL57_14695	COG0719	Fe-S assembly protein
AVL57_14700	COG1104	cysteine desulfurase activity
AVL57_14715	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVL57_14720	COG0483	inositol monophosphate 1-phosphatase activity
AVL57_14750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL57_14755	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AVL57_14760	COG1862	Preprotein translocase
AVL57_14765	COG0343	queuine tRNA-ribosyltransferase activity
AVL57_14780	COG3789	protein conserved in bacteria
AVL57_14785	COG1842	Phage shock protein A
AVL57_14810	COG0754	glutathionylspermidine amidase activity
AVL57_14825	COG2066	Belongs to the glutaminase family
AVL57_14830	COG1785	Belongs to the alkaline phosphatase family
AVL57_14885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AVL57_14890	COG1045	serine acetyltransferase
AVL57_14915	COG0438	transferase activity, transferring glycosyl groups
AVL57_14960	COG0463	Glycosyl transferase, family 2
AVL57_14960	COG1216	Glycosyl transferase, family 2
AVL57_14995	COG0489	protein tyrosine kinase activity
AVL57_15005	COG3409	Peptidoglycan-binding domain 1 protein
AVL57_15005	COG3267	Type II secretory pathway component ExeA
AVL57_15010	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AVL57_15010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVL57_15015	COG2827	Endonuclease containing a URI domain
AVL57_15035	COG1560	Kdo2-lipid A biosynthetic process
AVL57_15065	COG1960	acyl-CoA dehydrogenase activity
AVL57_15080	COG1435	thymidine kinase activity
AVL57_15090	COG1609	Transcriptional regulator
AVL57_15095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVL57_15135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AVL57_15140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVL57_15145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVL57_15150	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AVL57_15175	COG2815	serine threonine protein kinase
AVL57_15175	COG0515	serine threonine protein kinase
AVL57_15210	COG4774	siderophore transport
AVL57_15225	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_15240	COG4774	siderophore transport
AVL57_15240	COG1629	transport
AVL57_15245	COG4682	membrane
AVL57_15260	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AVL57_15265	COG0789	Transcriptional regulator
AVL57_15280	COG0189	ligase activity
AVL57_15295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AVL57_15335	COG1960	acyl-CoA dehydrogenase activity
AVL57_15365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVL57_15375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVL57_15425	COG1607	acyl-coa hydrolase
AVL57_15430	COG0826	peptidase U32
AVL57_15495	COG0583	DNA-binding transcription factor activity
AVL57_15510	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_15515	COG1733	regulation of RNA biosynthetic process
AVL57_15530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVL57_15565	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_15575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVL57_15580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVL57_15595	COG0109	protoheme IX farnesyltransferase activity
AVL57_15610	COG0583	DNA-binding transcription factor activity
AVL57_15625	COG4221	oxidoreductase activity
AVL57_15630	COG0693	protein deglycase activity
AVL57_15680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVL57_15685	COG1335	isochorismatase
AVL57_15690	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AVL57_15710	COG4771	TonB-dependent receptor
AVL57_15745	COG1566	PFAM secretion protein HlyD family protein
AVL57_15750	COG1846	Transcriptional regulator
AVL57_15760	COG1295	ribonuclease BN
AVL57_15770	COG0514	ATP-dependent DNA helicase (RecQ)
AVL57_15775	COG4681	YaeQ
AVL57_15795	COG0583	DNA-binding transcription factor activity
AVL57_15805	COG0484	heat shock protein binding
AVL57_15810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AVL57_15810	COG1017	nitric oxide dioxygenase activity
AVL57_15825	COG3604	Transcriptional regulator
AVL57_15850	COG4249	Peptidase C14 caspase catalytic subunit p20
AVL57_15850	COG2319	Wd-40 repeat
AVL57_15865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVL57_15885	COG1451	nucleotide metabolic process
AVL57_15900	COG0653	protein targeting
AVL57_15935	COG2133	pyrroloquinoline quinone binding
AVL57_15945	COG0697	spore germination
AVL57_15950	COG0513	Belongs to the DEAD box helicase family
AVL57_16000	COG2814	Major facilitator Superfamily
AVL57_16010	COG0656	L-ascorbic acid biosynthetic process
AVL57_16075	COG0583	DNA-binding transcription factor activity
AVL57_16095	COG1621	beta-fructofuranosidase activity
AVL57_16100	COG0477	Major facilitator Superfamily
AVL57_16110	COG4206	TonB-dependent receptor
AVL57_16110	COG1629	transport
AVL57_16135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL57_16140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVL57_16145	COG0006	proline dipeptidase activity
AVL57_16160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL57_16165	COG1957	nucleoside hydrolase
AVL57_16175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVL57_16180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVL57_16185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL57_16205	COG3313	Fe-S protein
AVL57_16245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL57_16250	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVL57_16255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AVL57_16260	COG2186	Transcriptional regulator
AVL57_16285	COG4969	Belongs to the N-Me-Phe pilin family
AVL57_16290	COG1459	type II secretion system
AVL57_16300	COG0237	dephospho-CoA kinase activity
AVL57_16300	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVL57_16305	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AVL57_16315	COG2988	succinylglutamate desuccinylase activity
AVL57_16320	COG0494	nUDIX hydrolase
AVL57_16330	COG0739	heme binding
AVL57_16335	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AVL57_16345	COG0849	cell division
AVL57_16350	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVL57_16355	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVL57_16360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVL57_16370	COG0772	Belongs to the SEDS family
AVL57_16375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVL57_16385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AVL57_16390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVL57_16395	COG0768	penicillin binding
AVL57_16400	COG3116	cell division
AVL57_16410	COG2001	Belongs to the MraZ family
AVL57_16450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVL57_16450	COG0678	peroxiredoxin activity
AVL57_16455	COG2203	Gaf domain
AVL57_16455	COG5001	Diguanylate cyclase
AVL57_16455	COG4251	negative regulation of phosphorylation
AVL57_16455	COG3706	GGDEF domain
AVL57_16465	COG2204	response regulator
AVL57_16470	COG5002	protein histidine kinase activity
AVL57_16470	COG2198	Histidine kinase
AVL57_16470	COG0784	Response regulator, receiver
AVL57_16490	COG0668	transmembrane transport
AVL57_16495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AVL57_16500	COG0189	ligase activity
AVL57_16505	COG1678	Uncharacterized ACR, COG1678
AVL57_16510	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVL57_16530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVL57_16535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AVL57_16540	COG0762	integral membrane protein
AVL57_16555	COG1902	pentaerythritol trinitrate reductase activity
AVL57_16555	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVL57_16570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVL57_16575	COG0625	glutathione transferase activity
AVL57_16605	COG0083	homoserine kinase activity
AVL57_16615	COG0583	DNA-binding transcription factor activity
AVL57_16625	COG2197	response regulator
AVL57_16630	COG4585	Histidine kinase
AVL57_16650	COG0640	Transcriptional regulator
AVL57_16660	COG0431	NADPH-dependent FMN reductase
AVL57_16665	COG0798	PFAM Bile acid sodium symporter
AVL57_16670	COG2201	protein-glutamate methylesterase activity
AVL57_16675	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AVL57_16680	COG0745	RESPONSE REGULATOR receiver
AVL57_16685	COG5002	protein histidine kinase activity
AVL57_16710	COG1748	Saccharopine dehydrogenase
AVL57_16725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AVL57_16730	COG3107	peptidoglycan biosynthetic process
AVL57_16735	COG0792	nuclease activity
AVL57_16745	COG2823	Periplasmic or secreted lipoprotein
AVL57_16790	COG4585	Histidine kinase
AVL57_16795	COG2197	response regulator
AVL57_16800	COG4771	TonB-dependent receptor
AVL57_16810	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVL57_16815	COG0372	Belongs to the citrate synthase family
AVL57_16825	COG2828	Protein conserved in bacteria
AVL57_16830	COG3706	GGDEF domain
AVL57_16875	COG2198	Histidine kinase
AVL57_16875	COG0784	Response regulator, receiver
AVL57_16875	COG5002	protein histidine kinase activity
AVL57_16880	COG0067	glutamate synthase
AVL57_16880	COG0069	glutamate synthase activity
AVL57_16880	COG0070	glutamate synthase
AVL57_16885	COG0493	'glutamate synthase
AVL57_16895	COG1476	TRANSCRIPTIONal
AVL57_16920	COG3866	Pectate lyase
AVL57_16935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVL57_16950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AVL57_16970	COG0739	heme binding
AVL57_16975	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVL57_16985	COG0738	Major facilitator superfamily
AVL57_16990	COG3659	wide pore channel activity
AVL57_16995	COG1902	pentaerythritol trinitrate reductase activity
AVL57_17005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVL57_17010	COG0625	glutathione transferase activity
AVL57_17030	COG2894	cell division
AVL57_17035	COG0850	regulation of cytokinetic process
AVL57_17075	COG1914	H( )-stimulated, divalent metal cation uptake system
AVL57_17080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AVL57_17100	COG0174	glutamine synthetase
AVL57_17110	COG3852	Histidine kinase
AVL57_17120	COG3437	response regulator, receiver
AVL57_17125	COG0204	Acyl-transferase
AVL57_17140	COG3706	GGDEF domain
AVL57_17155	COG0525	valine-tRNA ligase activity
AVL57_17160	COG2927	DNA polymerase III (CHI subunit)
AVL57_17165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVL57_17170	COG0795	lipopolysaccharide-transporting ATPase activity
AVL57_17175	COG0795	lipopolysaccharide-transporting ATPase activity
AVL57_17225	COG4264	IucA IucC family
AVL57_17230	COG0318	PFAM AMP-dependent synthetase and ligase
AVL57_17240	COG1082	Xylose isomerase domain protein TIM barrel
AVL57_17325	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVL57_17385	COG4191	Histidine kinase
AVL57_17395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVL57_17425	COG3706	GGDEF domain
AVL57_17430	COG3706	GGDEF domain
AVL57_17470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVL57_17475	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVL57_17480	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AVL57_17490	COG0535	radical SAM domain protein
AVL57_17520	COG0784	Response regulator, receiver
AVL57_17520	COG2205	protein histidine kinase activity
AVL57_17530	COG0348	domain, Protein
AVL57_17530	COG3901	Regulator of nitric oxide reductase transcription
AVL57_17535	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_17540	COG2197	response regulator
AVL57_17545	COG4585	Histidine kinase
AVL57_17575	COG4771	TonB-dependent receptor
AVL57_17580	COG1858	cytochrome C peroxidase
AVL57_17610	COG1028	Short-chain dehydrogenase reductase Sdr
AVL57_17620	COG1917	Cupin 2, conserved barrel domain protein
AVL57_17625	COG2271	Major facilitator Superfamily
AVL57_17645	COG1716	ATPase activity
AVL57_17680	COG0515	serine threonine protein kinase
AVL57_17680	COG1357	PFAM Pentapeptide repeats (8 copies)
AVL57_17695	COG1716	ATPase activity
AVL57_17695	COG1131	(ABC) transporter
AVL57_17695	COG0842	Transport permease protein
AVL57_17700	COG0513	Belongs to the DEAD box helicase family
AVL57_17705	COG0800	Aldolase
AVL57_17710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL57_17715	COG2186	Transcriptional regulator
AVL57_17725	COG3264	Mechanosensitive ion channel
AVL57_17725	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AVL57_17760	COG3568	Endonuclease Exonuclease Phosphatase
AVL57_17775	COG0730	response to heat
AVL57_17795	COG4191	Histidine kinase
AVL57_17805	COG0417	DNA replication proofreading
AVL57_17855	COG1309	transcriptional regulator
AVL57_17870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL57_17880	COG1573	uracil-dna glycosylase
AVL57_17885	COG3300	MHYT domain
AVL57_17885	COG5001	Diguanylate cyclase
AVL57_17905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AVL57_17910	COG4771	TonB-dependent receptor
AVL57_17935	COG1842	Phage shock protein A
AVL57_17945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL57_17970	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVL57_17975	COG0204	Acyl-transferase
AVL57_17980	COG0204	Acyl-transferase
AVL57_17985	COG0668	transmembrane transport
AVL57_18000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVL57_18005	COG0733	neurotransmitter:sodium symporter activity
AVL57_18020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVL57_18035	COG0716	FMN binding
AVL57_18045	COG0848	biopolymer transport protein
AVL57_18055	COG0457	Tetratricopeptide repeat
AVL57_18085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AVL57_18090	COG0702	epimerase
AVL57_18105	COG5001	Diguanylate cyclase
AVL57_18105	COG5002	protein histidine kinase activity
AVL57_18115	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AVL57_18120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL57_18130	COG0583	DNA-binding transcription factor activity
AVL57_18135	COG0121	glutamine amidotransferase
AVL57_18150	COG1522	sequence-specific DNA binding
AVL57_18165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVL57_18175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVL57_18185	COG1477	protein flavinylation
AVL57_18190	COG2871	sodium ion transport
AVL57_18195	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL57_18200	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL57_18205	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AVL57_18210	COG1805	sodium ion transport
AVL57_18220	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVL57_18225	COG0545	Peptidyl-prolyl cis-trans isomerase
AVL57_18230	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AVL57_18240	COG0039	L-malate dehydrogenase activity
AVL57_18245	COG1438	arginine binding
AVL57_18275	COG0572	uridine kinase
AVL57_18280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AVL57_18295	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AVL57_18305	COG0745	RESPONSE REGULATOR receiver
AVL57_18305	COG3706	GGDEF domain
AVL57_18315	COG0517	IMP dehydrogenase activity
AVL57_18315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVL57_18320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL57_18340	COG0189	ligase activity
AVL57_18350	COG0189	ligase activity
AVL57_18350	COG4067	protein conserved in archaea
AVL57_18365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVL57_18380	COG1283	sodium-dependent phosphate transmembrane transporter activity
AVL57_18385	COG0667	Aldo Keto reductase
AVL57_18400	COG0753	catalase activity
AVL57_18450	COG0583	DNA-binding transcription factor activity
AVL57_18510	COG0438	transferase activity, transferring glycosyl groups
AVL57_18510	COG1216	Glycosyl transferase, family 2
AVL57_18535	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVL57_18550	COG3119	arylsulfatase activity
AVL57_18565	COG0438	transferase activity, transferring glycosyl groups
AVL57_18565	COG1216	Glycosyl transferase, family 2
AVL57_18570	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AVL57_18570	COG0662	Cupin 2, conserved barrel domain protein
AVL57_18580	COG0202	RNA polymerase activity
AVL57_18600	COG0201	protein transport
AVL57_18620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVL57_18655	COG5002	protein histidine kinase activity
AVL57_18655	COG0784	Response regulator, receiver
AVL57_18675	COG0557	exoribonuclease II activity
AVL57_18690	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AVL57_18705	COG0543	2 iron, 2 sulfur cluster binding
AVL57_18710	COG2234	aminopeptidase activity
AVL57_18730	COG1271	oxidase subunit
AVL57_18735	COG1294	oxidase, subunit
AVL57_18740	COG0840	transmembrane signaling receptor activity
AVL57_18745	COG1522	sequence-specific DNA binding
AVL57_18760	COG1278	Cold shock
AVL57_18765	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVL57_18785	COG0339	signal peptide processing
AVL57_18790	COG2201	protein-glutamate methylesterase activity
AVL57_18810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVL57_18815	COG0243	molybdopterin cofactor binding
AVL57_18820	COG4946	Tricorn protease homolog
AVL57_18820	COG0793	Belongs to the peptidase S41A family
AVL57_18860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVL57_18865	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVL57_18870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AVL57_18885	COG0281	malic enzyme
AVL57_18890	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AVL57_18895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AVL57_18925	COG0456	acetyltransferase
AVL57_18935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL57_18940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AVL57_18945	COG2177	Part of the ABC transporter FtsEX involved in
AVL57_18950	COG2884	Cell division ATP-binding protein ftsE
AVL57_18955	COG0552	protein localization to endoplasmic reticulum
AVL57_18960	COG0742	ribosomal rna small subunit methyltransferase
AVL57_18970	COG2095	MarC family integral membrane protein
AVL57_18990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AVL57_18995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVL57_19005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AVL57_19020	COG0076	glutamate decarboxylase activity
AVL57_19025	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVL57_19035	COG0842	Transport permease protein
AVL57_19040	COG1131	(ABC) transporter
AVL57_19045	COG0745	RESPONSE REGULATOR receiver
AVL57_19050	COG2205	protein histidine kinase activity
AVL57_19055	COG4774	siderophore transport
AVL57_19075	COG1253	flavin adenine dinucleotide binding
AVL57_19080	COG0701	Predicted permease
AVL57_19085	COG1966	Carbon starvation protein
AVL57_19140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVL57_19145	COG0049	tRNA binding
AVL57_19150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVL57_19155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVL57_19160	COG0085	RNA polymerase activity
AVL57_19165	COG0222	ribosome binding
AVL57_19170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVL57_19175	COG0081	regulation of translation
AVL57_19180	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVL57_19185	COG0250	Participates in transcription elongation, termination and antitermination
AVL57_19190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVL57_19200	COG1132	(ABC) transporter
AVL57_19205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVL57_19210	COG3590	peptidase
AVL57_19220	COG0513	Belongs to the DEAD box helicase family
AVL57_19225	COG0418	dihydroorotase activity
AVL57_19235	COG3040	lipid binding
AVL57_19240	COG4989	oxidoreductase activity
AVL57_19245	COG0346	lactoylglutathione lyase activity
AVL57_19260	COG0302	gtp cyclohydrolase
AVL57_19280	COG2957	Belongs to the agmatine deiminase family
AVL57_19285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVL57_19300	COG3306	glycosyltransferase involved in LPS biosynthesis
AVL57_19305	COG1201	RNA secondary structure unwinding
AVL57_19315	COG1793	dna ligase
AVL57_19325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVL57_19340	COG0625	glutathione transferase activity
AVL57_19355	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AVL57_19360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVL57_19370	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_19385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVL57_19390	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AVL57_19395	COG0330	HflC and HflK could
AVL57_19400	COG0330	HflC and HflK could
AVL57_19405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVL57_19410	COG1923	regulation of RNA biosynthetic process
AVL57_19415	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVL57_19430	COG0802	atpase or kinase
AVL57_19435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVL57_19435	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVL57_19440	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVL57_19450	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVL57_19455	COG2816	NAD+ diphosphatase activity
AVL57_19460	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AVL57_19465	COG0735	belongs to the Fur family
AVL57_19475	COG0432	Pfam Uncharacterised protein family UPF0047
AVL57_19485	COG0305	Participates in initiation and elongation during chromosome replication
AVL57_19510	COG2258	MOSC domain
AVL57_19540	COG5002	protein histidine kinase activity
AVL57_19555	COG4191	Histidine kinase
AVL57_19555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVL57_19565	COG1609	Transcriptional regulator
AVL57_19570	COG2211	Major facilitator Superfamily
AVL57_19575	COG2723	6-phospho-beta-galactosidase activity
AVL57_19585	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVL57_19590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVL57_19595	COG4558	Periplasmic binding protein
AVL57_19605	COG4206	TonB-dependent receptor
AVL57_19615	COG1472	Belongs to the glycosyl hydrolase 3 family
AVL57_19630	COG2855	membrane
AVL57_19635	COG2175	clavaminate synthase activity
AVL57_19640	COG0656	L-ascorbic acid biosynthetic process
AVL57_19660	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AVL57_19665	COG1230	cation diffusion facilitator family transporter
AVL57_19700	COG4771	TonB-dependent receptor
AVL57_19705	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AVL57_19710	COG4988	ABC transporter
AVL57_19720	COG1294	oxidase, subunit
AVL57_19735	COG2204	response regulator
AVL57_19770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVL57_19795	COG4319	ketosteroid isomerase
AVL57_19835	COG3237	CsbD-like
AVL57_19880	COG2267	carboxylic ester hydrolase activity
AVL57_19905	COG3038	cytochrome b561
AVL57_19910	COG2353	YceI-like domain
AVL57_19915	COG1252	NADH dehydrogenase
AVL57_19940	COG2067	long-chain fatty acid transport protein
AVL57_19945	COG2130	NADP-dependent
AVL57_19950	COG5001	Diguanylate cyclase
AVL57_19950	COG4251	negative regulation of phosphorylation
AVL57_19950	COG2203	Gaf domain
AVL57_19950	COG3706	GGDEF domain
AVL57_19970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVL57_19980	COG4181	ATPase activity
AVL57_20000	COG0523	cobalamin synthesis protein
AVL57_20015	COG4771	TonB-dependent receptor
AVL57_20035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVL57_20040	COG1349	DNA-binding transcription factor activity
AVL57_20055	COG0697	spore germination
AVL57_20060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVL57_20065	COG4977	sequence-specific DNA binding
AVL57_20075	COG1166	arginine decarboxylase activity
AVL57_20085	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AVL57_20090	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AVL57_20095	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AVL57_20105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVL57_20135	COG4232	protein-disulfide reductase activity
AVL57_20140	COG0739	heme binding
AVL57_20145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVL57_20150	COG0511	ligase activity, forming carbon-carbon bonds
AVL57_20155	COG0439	Biotin carboxylase
AVL57_20175	COG2176	DNA-directed DNA polymerase activity
AVL57_20195	COG0154	amidase activity
AVL57_20210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVL57_20215	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AVL57_20230	COG0151	Belongs to the GarS family
AVL57_20240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVL57_20250	COG3954	Phosphoribulokinase
AVL57_20255	COG2233	PERMEase
AVL57_20270	COG0745	RESPONSE REGULATOR receiver
AVL57_20290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AVL57_20300	COG3031	protein transport across the cell outer membrane
AVL57_20310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVL57_20315	COG1459	type II secretion system
AVL57_20320	COG2165	general secretion pathway protein
AVL57_20330	COG2165	general secretion pathway protein
AVL57_20335	COG4795	General secretion pathway protein
AVL57_20350	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AVL57_20360	COG1234	tRNA 3'-trailer cleavage
AVL57_20365	COG1012	belongs to the aldehyde dehydrogenase family
AVL57_20375	COG1011	Hydrolase
AVL57_20380	COG0494	nUDIX hydrolase
AVL57_20385	COG1218	3'(2'),5'-bisphosphate nucleotidase
AVL57_20400	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AVL57_20410	COG3089	Belongs to the UPF0270 family
AVL57_20415	COG0429	hydrolase of the alpha beta-hydrolase fold
AVL57_20425	COG0488	(ABC) transporter
AVL57_20450	COG0545	Peptidyl-prolyl cis-trans isomerase
AVL57_20460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVL57_20465	COG2183	response to ionizing radiation
AVL57_20480	COG0596	Alpha beta hydrolase
AVL57_20485	COG1040	competence protein
AVL57_20505	COG1794	racemase activity, acting on amino acids and derivatives
AVL57_20520	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AVL57_20525	COG0534	Mate efflux family protein
AVL57_20540	COG1999	signal sequence binding
AVL57_20545	COG0109	protoheme IX farnesyltransferase activity
AVL57_20550	COG1612	heme a metabolic process
AVL57_20575	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AVL57_20580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVL57_20585	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AVL57_20585	COG1565	acr, cog1565
AVL57_20615	COG0129	dihydroxy-acid dehydratase activity
AVL57_20620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVL57_20630	COG0606	chelatase, subunit chli
AVL57_20635	COG0583	DNA-binding transcription factor activity
AVL57_20645	COG2814	Major facilitator Superfamily
AVL57_20655	COG0729	surface antigen
AVL57_20660	COG2911	Protein conserved in bacteria
AVL57_20685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVL57_20695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVL57_20715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVL57_20765	COG0425	Belongs to the sulfur carrier protein TusA family
AVL57_20780	COG1561	YicC-like family, N-terminal region
AVL57_20810	COG2723	6-phospho-beta-galactosidase activity
AVL57_20815	COG2211	Major facilitator Superfamily
AVL57_20820	COG1609	Transcriptional regulator
AVL57_20835	COG2199	diguanylate cyclase activity
AVL57_20835	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AVL57_20865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVL57_20885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVL57_20890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVL57_20910	COG1475	DNA binding
AVL57_20915	COG1192	Involved in chromosome partitioning
AVL57_20940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AVL57_20945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVL57_20955	COG0706	membrane insertase activity
AVL57_20960	COG0594	ribonuclease P activity
AVL57_20965	COG0230	Belongs to the bacterial ribosomal protein bL34 family