locus-tag	class	description
A6K25_00010	ENOG4108M1T	Cytochrome c-type biogenesis protein
A6K25_00015	ENOG4107QX9	Thiol disulfide interChange protein
A6K25_00020	ENOG4105DA4	cytochrome c-type biogenesis protein
A6K25_00025	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
A6K25_00030	ENOG4105X3C	heme exporter protein
A6K25_00035	ENOG41060IM	Heme exporter protein
A6K25_00040	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A6K25_00045	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
A6K25_00065	ENOG4108SDH	ABC, transporter
A6K25_00070	ENOG4108IUW	ABC transporter
A6K25_00075	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A6K25_00085	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A6K25_00090	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A6K25_00095	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A6K25_00115	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A6K25_00120	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A6K25_00125	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6K25_00130	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6K25_00135	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6K25_00150	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A6K25_00155	ENOG4105C1J	atp-dependent rna helicase
A6K25_00160	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A6K25_00165	ENOG4105CSA	Coproporphyrinogen iii oxidase
A6K25_00195	ENOG41067MG	lrgb family
A6K25_00235	ENOG4105EGI	Transcriptional regulator
A6K25_00240	ENOG4108KPZ	tonB-dependent Receptor
A6K25_00265	ENOG4108NRW	Phospholipase, patatin family
A6K25_00280	ENOG4107RNH	Outer membrane receptor FepA
A6K25_00300	ENOG4105C5H	ABC transporter
A6K25_00310	ENOG4105CE4	GlcNAc 6-P deacetylase
A6K25_00315	ENOG4105RD7	BadF BadG BcrA BcrD
A6K25_00325	ENOG4105BZU	Histidine kinase
A6K25_00330	ENOG4105EYH	Exonuclease
A6K25_00335	ENOG4107RH8	nuclease SbcCD subunit D
A6K25_00340	ENOG4107SDU	Methyl-accepting chemotaxis
A6K25_00345	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A6K25_00360	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A6K25_00365	ENOG4105K56	Transcriptional regulator
A6K25_00380	ENOG4105QV4	Tryptophan halogenase
A6K25_00385	ENOG4106R3P	AraC family transcriptional regulator
A6K25_00390	ENOG4105E08	Glycoside hydrolase, family 9
A6K25_00395	ENOG4105C93	Xylose Isomerase
A6K25_00400	ENOG4105CMG	Carbohydrate kinase
A6K25_00405	ENOG4105T16	Transcriptional regulator (AraC family)
A6K25_00425	ENOG4105BZU	Histidine kinase
A6K25_00430	ENOG4108UT2	hemolysin iii
A6K25_00455	ENOG4105C5Q	Transcriptional regulator
A6K25_00465	ENOG4105CJ3	phosphate transporter
A6K25_00475	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A6K25_00480	ENOG4105E2Z	phosphate ABC transporter (Permease
A6K25_00485	ENOG4105C8U	phosphate abc transporter
A6K25_00500	ENOG4105C9X	ppx gppa phosphatase
A6K25_00505	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A6K25_00510	ENOG4105WYW	fructose-bisphosphate aldolase
A6K25_00515	ENOG4105BZA	Phosphoglycerate kinase
A6K25_00520	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A6K25_00525	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A6K25_00530	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A6K25_00550	ENOG4108I6A	alcohol dehydrogenase
A6K25_00555	ENOG4105CF7	AraC family transcriptional regulator
A6K25_00560	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
A6K25_00565	ENOG4105BZU	Histidine kinase
A6K25_00570	ENOG4105BZU	Histidine kinase
A6K25_00580	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
A6K25_00585	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6K25_00610	ENOG4105CDY	transcriptional regulatory protein
A6K25_00615	ENOG4105D6Z	AFG1 family ATPase
A6K25_00625	ENOG4105C0H	protease
A6K25_00630	ENOG4105C0H	protease
A6K25_00635	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A6K25_00640	ENOG4105VFK	BolA family
A6K25_00650	ENOG4105E3I	toluene tolerance
A6K25_00655	ENOG4107PE3	Mammalian cell entry related domain protein
A6K25_00660	ENOG4105CY3	ABC transporter, permease
A6K25_00665	ENOG4105DHJ	ABC, transporter
A6K25_00675	ENOG4105C2X	Arabinose 5-phosphate isomerase
A6K25_00680	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A6K25_00695	ENOG4108IUZ	ABC transporter
A6K25_00705	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
A6K25_00710	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A6K25_00715	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A6K25_00720	ENOG41080Z8	PHOSPHOCARRIER protein
A6K25_00725	ENOG4105CJW	magnesium transporter
A6K25_00740	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A6K25_00745	ENOG4105KB2	stringent starvation protein b
A6K25_00750	ENOG4107MKT	Stringent starvation protein a
A6K25_00755	ENOG4105EIX	cytochrome c1
A6K25_00760	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6K25_00765	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A6K25_00770	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
A6K25_00780	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A6K25_00790	ENOG4108SF5	RNA Polymerase
A6K25_00795	ENOG4108UJD	30S ribosomal protein S9
A6K25_00800	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A6K25_00815	ENOG4105DXN	mazG family
A6K25_00820	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A6K25_00825	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A6K25_00830	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A6K25_00835	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A6K25_00840	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
A6K25_00850	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A6K25_00855	ENOG4105T95	Thiol disulfide interChange protein
A6K25_00860	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A6K25_00865	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
A6K25_00870	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A6K25_00875	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A6K25_00880	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A6K25_00895	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A6K25_00900	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_00905	ENOG4105CFH	Aspartokinase
A6K25_00915	ENOG4107QIJ	Aconitate hydratase 2
A6K25_00925	ENOG4107QIJ	Aconitate hydratase 2
A6K25_00940	ENOG4105CEY	Amp-dependent synthetase and ligase
A6K25_00945	ENOG4105BZU	Histidine kinase
A6K25_00950	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6K25_00955	ENOG41061N2	exported protein
A6K25_00965	ENOG41067XB	TonB family
A6K25_00970	ENOG4109015	Biopolymer transport protein exbD tolR
A6K25_01010	ENOG4105BZU	Histidine kinase
A6K25_01015	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6K25_01020	ENOG4105BZU	Histidine kinase
A6K25_01025	ENOG4105DH7	May be involved in recombination (By similarity)
A6K25_01030	ENOG4108JCI	Transcriptional regulator
A6K25_01035	ENOG4105DKK	Benzoate
A6K25_01050	ENOG4105K59	histidine triad (HIT) protein
A6K25_01055	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A6K25_01070	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A6K25_01080	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6K25_01085	ENOG4105VCC	30S ribosomal protein S21
A6K25_01090	ENOG4105KTH	gatB Yqey
A6K25_01095	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A6K25_01100	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6K25_01105	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_01120	ENOG4105BZS	acriflavin resistance protein
A6K25_01125	ENOG410624X	efflux transporter, rnd family, mfp subunit
A6K25_01135	ENOG4105MP9	class II Aldolase
A6K25_01140	ENOG4105CXK	mandelate racemase muconate lactonizing
A6K25_01160	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
A6K25_01165	ENOG4105CSU	acyl-Coa dehydrogenase
A6K25_01180	ENOG4105C58	cytochrome c oxidase accessory protein ccog
A6K25_01185	ENOG4105E27	serine threonine protein kinase
A6K25_01190	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A6K25_01195	ENOG4108Z33	Thiol disulfide Interchange Protein
A6K25_01210	ENOG4105D7T	ABC transporter
A6K25_01215	ENOG4105DG7	nitrate ABC transporter
A6K25_01230	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A6K25_01235	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6K25_01245	ENOG4105WZK	nitrite reductase NADPH small subunit
A6K25_01250	ENOG4107QZF	nitrite reductase NADPH large subunit
A6K25_01255	ENOG4105CHH	sulfate transporter
A6K25_01275	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
A6K25_01280	ENOG4105M85	Bola protein
A6K25_01290	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A6K25_01295	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6K25_01310	ENOG4105UGU	tonB-dependent Receptor
A6K25_01315	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A6K25_01320	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6K25_01325	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A6K25_01345	ENOG4107VXZ	Hydrolase
A6K25_01350	ENOG4105BZU	Histidine kinase
A6K25_01355	ENOG4105BZU	Histidine kinase
A6K25_01360	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6K25_01365	ENOG4105IPS	esterase
A6K25_01380	ENOG41087AY	ADP-Ribose pyrophosphatase
A6K25_01385	ENOG4105DFG	type I secretion outer membrane protein
A6K25_01400	ENOG4105C1J	atp-dependent rna helicase
A6K25_01405	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A6K25_01415	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A6K25_01420	ENOG4105CBG	Sulfatase
A6K25_01425	ENOG4105QRC	ig domain protein group 2 domain protein
A6K25_01455	ENOG41061MV	Arylsulfatase
A6K25_01485	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A6K25_01555	ENOG4106A3M	Cytochrome p-450
A6K25_01580	ENOG4105DIA	mandelate racemase muconate lactonizing
A6K25_01585	ENOG4105CPQ	Dehydrogenase
A6K25_01590	ENOG4105CHR	reductase
A6K25_01595	ENOG4105C26	Dehydrogenase
A6K25_01600	ENOG4105CBG	Sulfatase
A6K25_01605	ENOG4108WYP	Transcriptional regulator
A6K25_01615	ENOG4108IAB	Phoh family
A6K25_01625	ENOG4105D3G	Pseudouridine synthase
A6K25_01645	ENOG4105BZU	Histidine kinase
A6K25_01650	ENOG4105BZU	Histidine kinase
A6K25_01655	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A6K25_01660	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
A6K25_01665	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A6K25_01670	ENOG4105HF0	Membrane
A6K25_01675	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
A6K25_01680	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A6K25_01695	ENOG4105I7R	Adenylate cyclase
A6K25_01700	ENOG4106MWK	domain protein
A6K25_01705	ENOG4105F3H	Histidine kinase
A6K25_01710	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A6K25_01715	ENOG4105BZS	acriflavin resistance protein
A6K25_01730	ENOG4105C26	Dehydrogenase
A6K25_01735	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_01745	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A6K25_01750	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A6K25_01760	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A6K25_01765	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A6K25_01770	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A6K25_01775	ENOG4108UM1	dedA family
A6K25_01810	ENOG4108VEQ	Superoxide dismutase
A6K25_01820	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A6K25_01825	ENOG4105K46	50S ribosomal protein l27
A6K25_01830	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A6K25_01835	ENOG4105EAH	synthase
A6K25_01845	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
A6K25_01850	ENOG4107SC1	transglycosylase
A6K25_01855	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A6K25_01860	ENOG4105CHU	acetyl-coa acetyltransferase
A6K25_01930	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A6K25_01985	ENOG4108UV1	cellular component movement
A6K25_02045	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
A6K25_02095	ENOG4105K3M	)-transporter
A6K25_02105	ENOG4108N3W	hemolysin secretion protein
A6K25_02120	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
A6K25_02135	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A6K25_02140	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A6K25_02145	ENOG4105EHZ	conserved protein UCP016719
A6K25_02165	ENOG4107S6Z	Na H antiporter
A6K25_02170	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6K25_02185	ENOG4105C26	Dehydrogenase
A6K25_02190	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A6K25_02205	ENOG4107QR8	Thioredoxin
A6K25_02235	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A6K25_02240	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A6K25_02245	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6K25_02255	ENOG4105CH2	amidohydrolase
A6K25_02265	ENOG4105K63	Thioredoxin
A6K25_02270	ENOG4105C1J	atp-dependent rna helicase
A6K25_02275	ENOG4105C9X	ppx gppa phosphatase
A6K25_02280	ENOG4105D52	delta-aminolevulinic acid dehydratase
A6K25_02285	ENOG4105BZU	Histidine kinase
A6K25_02300	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A6K25_02305	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A6K25_02310	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A6K25_02320	ENOG4108ZP8	Acetolactate synthase small subunit
A6K25_02325	ENOG4105C7K	acetolactate synthase
A6K25_02340	ENOG4107RDJ	Sulfotransferase
A6K25_02345	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A6K25_02360	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A6K25_02365	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A6K25_02370	ENOG4105DJ4	phosphatidylserine decarboxylase
A6K25_02380	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A6K25_02390	ENOG4105PXI	polysaccharide deacetylase
A6K25_02400	ENOG41063SB	peptidase
A6K25_02415	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
A6K25_02425	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A6K25_02435	ENOG4105E0F	Histidine kinase
A6K25_02440	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A6K25_02455	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A6K25_02465	ENOG4108Z5K	methylglyoxal synthase
A6K25_02470	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A6K25_02475	ENOG4105CAS	nag kinase
A6K25_02480	ENOG4105DBV	ornithine carbamoyltransferase
A6K25_02485	ENOG4105CDH	Citrulline--aspartate ligase
A6K25_02490	ENOG4105CH7	arginosuccinase
A6K25_02495	ENOG4107QZM	n-acetylglutamate synthase
A6K25_02500	ENOG4105BZU	Histidine kinase
A6K25_02535	ENOG4105CYM	Glutathione S-transferase
A6K25_02540	ENOG4107R1I	NAD-dependent malic enzyme
A6K25_02545	ENOG4108JQC	penicillin-binding protein 1A
A6K25_02570	ENOG4105E4G	Type IV pilus
A6K25_02575	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A6K25_02580	ENOG4105D49	3-dehydroquinate synthase
A6K25_02590	ENOG4105DFE	Dna adenine methylase
A6K25_02610	ENOG4105DJV	ribulose-phosphate 3-epimerase
A6K25_02615	ENOG4105C31	Tryptophanyl-tRNA synthetase
A6K25_02620	ENOG4105DDQ	anthranilate synthase
A6K25_02630	ENOG4105C8Y	Acetylornithine aminotransferase
A6K25_02640	ENOG4105C26	Dehydrogenase
A6K25_02650	ENOG4105BZU	Histidine kinase
A6K25_02660	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6K25_02665	ENOG4105BZU	Histidine kinase
A6K25_02690	ENOG4105CXT	aspartate transcarbamylase
A6K25_02695	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A6K25_02705	ENOG4105EZR	dyp-type peroxidase family protein
A6K25_02710	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6K25_02720	ENOG4108YZA	Nitrogen regulatory protein pii
A6K25_02740	ENOG4105CKW	Inner membrane protein yedI
A6K25_02750	ENOG4105BZ4	penicillin-binding protein
A6K25_02760	ENOG4105CVE	Lytic murein transglycosylase
A6K25_02765	ENOG4105CQ7	ATP-dependent helicase
A6K25_02785	ENOG4105DGW	oligopeptidase A
A6K25_02790	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_02810	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A6K25_02815	ENOG4105D16	lipopolysaccharide heptosyltransferase i
A6K25_02820	ENOG4105CPK	Glycosyl transferase (Group 1
A6K25_02825	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A6K25_02830	ENOG41083MP	50s ribosomal protein l29
A6K25_02835	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A6K25_02840	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A6K25_02845	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A6K25_02850	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A6K25_02855	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A6K25_02860	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A6K25_02865	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A6K25_02870	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A6K25_02875	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A6K25_02880	ENOG4107QHF	type ii secretion system protein e
A6K25_02890	ENOG4107QM5	aconitate hydratase
A6K25_02895	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A6K25_02900	ENOG4105C0A	alcohol dehydrogenase
A6K25_02950	ENOG4105ETE	Transcriptional regulator (LacI family
A6K25_02990	ENOG4105E53	ec 3.2.1.28
A6K25_03010	ENOG4105D0M	Protease HtpX homolog
A6K25_03025	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A6K25_03030	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A6K25_03035	ENOG4105BZU	Histidine kinase
A6K25_03040	ENOG4107SDU	Methyl-accepting chemotaxis
A6K25_03045	ENOG4108V3W	Chemotaxis protein, CheW
A6K25_03050	ENOG4105CBS	Chea signal transduction histidine kinase
A6K25_03055	ENOG4108VYJ	response regulator receiver protein
A6K25_03060	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_03075	ENOG410804D	Sensor Signal Transduction Histidine Kinase
A6K25_03105	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
A6K25_03110	ENOG4105CEN	a g-specific adenine glycosylase
A6K25_03120	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A6K25_03125	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
A6K25_03130	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A6K25_03135	ENOG4105BZU	Histidine kinase
A6K25_03140	ENOG41065U4	response regulator
A6K25_03145	ENOG4105CNT	hydrolase family 2
A6K25_03155	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A6K25_03160	ENOG4105N42	UPF0307 protein
A6K25_03170	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A6K25_03185	ENOG4105C03	ribonuclease
A6K25_03190	ENOG4108Z03	MAF-like protein
A6K25_03195	ENOG4105VQ7	Rod shape-determining protein MreD
A6K25_03200	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A6K25_03205	ENOG4105DFF	Rod shape-determining protein mreb
A6K25_03245	ENOG4105D7Q	type ii secretion system
A6K25_03250	ENOG4107QHF	type ii secretion system protein e
A6K25_03295	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A6K25_03300	ENOG4105E98	transcriptional regulator DeoR family
A6K25_03305	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A6K25_03315	ENOG4107RUZ	Sss sodium solute transporter superfamily
A6K25_03350	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A6K25_03355	ENOG4105D58	Diguanylate phosphodiesterase
A6K25_03360	ENOG4105BZU	Histidine kinase
A6K25_03365	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6K25_03380	ENOG4105IBP	Cyclic peptide transporter
A6K25_03400	ENOG4105CEY	Amp-dependent synthetase and ligase
A6K25_03410	ENOG4108TU9	TRANSCRIPTIONal
A6K25_03450	ENOG4107XMK	single-stranded DNA-binding protein
A6K25_03460	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A6K25_03465	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A6K25_03475	ENOG41060NJ	transcriptional regulator
A6K25_03485	ENOG4107VXZ	Hydrolase
A6K25_03490	ENOG4107RDB	Major Facilitator
A6K25_03495	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A6K25_03500	ENOG4105DFF	Rod shape-determining protein mreb
A6K25_03520	ENOG4105F0N	pyrophosphate phospho-hydrolase
A6K25_03525	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A6K25_03530	ENOG4105DFU	Cell wall formation (By similarity)
A6K25_03535	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A6K25_03545	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A6K25_03565	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A6K25_03570	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A6K25_03585	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
A6K25_03590	ENOG4105D7W	serine acetyltransferase
A6K25_03595	ENOG4105C4R	Atp-dependent dna helicase
A6K25_03600	ENOG4105BZU	Histidine kinase
A6K25_03605	ENOG4105FR1	rard protein
A6K25_03610	ENOG4105CJW	magnesium transporter
A6K25_03615	ENOG4108VUY	thioesterase Superfamily protein
A6K25_03620	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6K25_03630	ENOG4105CNG	UPF0061 protein
A6K25_03640	ENOG4105BZU	Histidine kinase
A6K25_03645	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
A6K25_03650	ENOG4108NST	exported protein
A6K25_03660	ENOG4108N3W	hemolysin secretion protein
A6K25_03675	ENOG4105CYC	Transferase
A6K25_03685	ENOG4105BZS	acriflavin resistance protein
A6K25_03690	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A6K25_03705	ENOG4105KPY	Small multidrug resistance protein
A6K25_03715	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
A6K25_03725	ENOG4105BZU	Histidine kinase
A6K25_03755	ENOG4105CBX	hi0933 family
A6K25_03760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6K25_03765	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
A6K25_03785	ENOG4105EHV	domain protein
A6K25_03790	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
A6K25_03795	ENOG4105CB5	ATP-dependent DNA helicase recG
A6K25_03800	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
A6K25_03805	ENOG4105KME	endoribonuclease L-psp
A6K25_03810	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A6K25_03815	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A6K25_03820	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A6K25_03830	ENOG4105BZU	Histidine kinase
A6K25_03835	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A6K25_03845	ENOG4105ECF	c-methyltransferase
A6K25_03850	ENOG410601J	HemY protein
A6K25_03855	ENOG4105IYK	transposase
A6K25_03860	ENOG4105DQ6	Transposase
A6K25_03865	ENOG4105CD3	dihydroorotase
A6K25_03870	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A6K25_03875	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A6K25_03880	ENOG4105C26	Dehydrogenase
A6K25_03890	ENOG4105EVZ	LysR family transcriptional regulator
A6K25_03895	ENOG4108R86	Transcriptional regulator
A6K25_03900	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
A6K25_03905	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
A6K25_03910	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
A6K25_03920	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
A6K25_03930	ENOG4105DYW	oxidoreductase
A6K25_03940	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A6K25_03950	ENOG41081QJ	UBA THIF-type NAD FAD binding
A6K25_03960	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A6K25_03965	ENOG4105D41	biosynthesis protein thiH
A6K25_03985	ENOG4105CM6	amino acid regulated cytosolic protein
A6K25_04000	ENOG4105DQS	Transcriptional regulator
A6K25_04005	ENOG4105C1G	acyl-Coa dehydrogenase
A6K25_04015	ENOG4105CMI	transporter
A6K25_04020	ENOG4105CJ1	ABC, transporter
A6K25_04025	ENOG4105D0S	secretion protein (HlyD
A6K25_04035	ENOG4105C26	Dehydrogenase
A6K25_04040	ENOG4108M0I	Transcriptional regulator
A6K25_04045	ENOG4105CNM	Receptor
A6K25_04050	ENOG4105BZU	Histidine kinase
A6K25_04055	ENOG4107RDJ	Sulfotransferase
A6K25_04065	ENOG4105C26	Dehydrogenase
A6K25_04070	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
A6K25_04075	ENOG4105CXK	mandelate racemase muconate lactonizing
A6K25_04080	ENOG4105C26	Dehydrogenase
A6K25_04095	ENOG4105ETT	transcriptional Regulator, LysR family
A6K25_04100	ENOG4105EJQ	L-serine dehydratase
A6K25_04140	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A6K25_04145	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A6K25_04155	ENOG4105DVW	rieske (2Fe-2S)
A6K25_04160	ENOG4105ECQ	AraC Family Transcriptional Regulator
A6K25_04195	ENOG4105DAA	L-lactate
A6K25_04200	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A6K25_04205	ENOG4105NI8	Cytosine-specific methyltransferase
A6K25_04210	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A6K25_04225	ENOG4105C94	Transporter
A6K25_04235	ENOG4105DFD	Na H antiporter
A6K25_04245	ENOG4105MPD	Cytochrome
A6K25_04250	ENOG4105BZU	Histidine kinase
A6K25_04255	ENOG4105C4R	Atp-dependent dna helicase
A6K25_04260	ENOG4105W0Z	cytoplasmic protein
A6K25_04265	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A6K25_04270	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
A6K25_04280	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
A6K25_04285	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A6K25_04290	ENOG4105CPQ	Dehydrogenase
A6K25_04295	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6K25_04300	ENOG4105BZU	Histidine kinase
A6K25_04315	ENOG4105DKP	glycosyl transferase, family 9
A6K25_04320	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
A6K25_04325	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A6K25_04330	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A6K25_04340	ENOG4105W0E	50S ribosomal protein L33
A6K25_04345	ENOG4105KDC	50s ribosomal protein l28
A6K25_04360	ENOG4105E3R	(LipO)protein
A6K25_04380	ENOG4105W5Q	DNA repair protein (RadC
A6K25_04385	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A6K25_04390	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A6K25_04400	ENOG4105IIU	Aminopeptidase
A6K25_04420	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A6K25_04430	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6K25_04505	ENOG4108Z0R	Transferase
A6K25_04510	ENOG4105E2X	shikimate dehydrogenase
A6K25_04520	ENOG4105EIF	outer membrane protein W
A6K25_04525	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A6K25_04530	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A6K25_04540	ENOG4108RPN	Protein smg homolog
A6K25_04545	ENOG4105C79	DNA protecting protein DprA
A6K25_04555	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A6K25_04565	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A6K25_04570	ENOG4105C1A	potassium transporter peripheral membrane
A6K25_04580	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
A6K25_04585	ENOG4105C2M	dna polymerase I
A6K25_04590	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A6K25_04595	ENOG4106RE7	Cytochrome
A6K25_04600	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
A6K25_04610	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A6K25_04615	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
A6K25_04620	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
A6K25_04635	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6K25_04640	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A6K25_04645	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A6K25_04655	ENOG4105VG0	50S ribosomal protein l34
A6K25_04660	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A6K25_04665	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A6K25_04670	ENOG4108VPT	UPF0234 protein
A6K25_04675	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A6K25_04680	ENOG4105QTB	Flavodoxin
A6K25_04695	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A6K25_04700	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A6K25_04705	ENOG4107QJE	Chromosome Partitioning Protein
A6K25_04710	ENOG4105FA0	parb-like partition protein
A6K25_04720	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A6K25_04725	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6K25_04730	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6K25_04735	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A6K25_04740	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A6K25_04745	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A6K25_04750	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A6K25_04755	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A6K25_04770	ENOG4108K3A	Glutathione S-transferase
A6K25_04785	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6K25_04790	ENOG4105CDV	Ompa motb domain protein
A6K25_04800	ENOG41060NJ	transcriptional regulator
A6K25_04805	ENOG4105CT4	transporter
A6K25_04825	ENOG4105QV4	Tryptophan halogenase
A6K25_04840	ENOG4105DSJ	YicC domain protein
A6K25_04845	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A6K25_04850	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A6K25_04855	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A6K25_04860	ENOG4108TM9	integral membrane protein
A6K25_04925	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A6K25_04935	ENOG4105C5I	Dehydrogenase
A6K25_04960	ENOG4105MA0	exported protein
A6K25_04965	ENOG4105CFU	surface antigen
A6K25_04975	ENOG4105C2C	drug resistance transporter, Bcr CflA
A6K25_04980	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A6K25_04985	ENOG4105EMY	transcriptional regulator
A6K25_04990	ENOG4105C0P	Mg chelatase subunit ChlI
A6K25_04995	ENOG4105EN6	Membrane
A6K25_05000	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A6K25_05005	ENOG4105C01	Dihydroxy-acid dehydratase
A6K25_05010	ENOG4105C7B	Threonine dehydratase
A6K25_05015	ENOG4105E55	glycerol-3-phosphate acyltransferase
A6K25_05030	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A6K25_05035	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
A6K25_05040	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A6K25_05045	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
A6K25_05070	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
A6K25_05075	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A6K25_05095	ENOG4107R73	Mate efflux family protein
A6K25_05100	ENOG4105F4I	Transcriptional regulator
A6K25_05125	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
A6K25_05135	ENOG4105MJ2	Competence protein
A6K25_05140	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A6K25_05155	ENOG4105BZM	domain protein
A6K25_05160	ENOG4108RRZ	Transcription elongation factor GreB
A6K25_05170	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6K25_05195	ENOG4105C5H	ABC transporter
A6K25_05205	ENOG4105DNZ	Alpha Beta Hydrolase
A6K25_05210	ENOG4105YP7	UPF0270 protein
A6K25_05220	ENOG4105DJ9	glucan biosynthesis protein
A6K25_05225	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
A6K25_05240	ENOG4107RK2	ADP-ribose diphosphatase NudE
A6K25_05245	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
A6K25_05255	ENOG4105C26	Dehydrogenase
A6K25_05260	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A6K25_05300	ENOG4108VAU	general secretion pathway protein G
A6K25_05305	ENOG4105D7Q	type ii secretion system
A6K25_05320	ENOG4108XKW	General secretion pathway protein C
A6K25_05325	ENOG4105VEJ	Heat shock protein
A6K25_05330	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A6K25_05335	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
A6K25_05345	ENOG4105E0F	Histidine kinase
A6K25_05350	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A6K25_05360	ENOG4105CNM	Receptor
A6K25_05365	ENOG4105C2W	permease
A6K25_05370	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
A6K25_05380	ENOG4105EYW	Ion transport protein
A6K25_05390	ENOG4105C12	Phosphoribosylglycinamide synthetase
A6K25_05400	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A6K25_05405	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
A6K25_05410	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A6K25_05415	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A6K25_05425	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A6K25_05445	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
A6K25_05465	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A6K25_05470	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A6K25_05475	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A6K25_05480	ENOG4105DR5	peptidase
A6K25_05485	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A6K25_05495	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A6K25_05500	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A6K25_05505	ENOG4105BZU	Histidine kinase
A6K25_05515	ENOG4105CKI	cobalamin synthesis protein
A6K25_05525	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
A6K25_05535	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A6K25_05540	ENOG4105W8H	transhydrogenase (subunit alpha
A6K25_05545	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A6K25_05555	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
A6K25_05560	ENOG41066YJ	Beta-lactamase
A6K25_05565	ENOG4105ECQ	AraC Family Transcriptional Regulator
A6K25_05570	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A6K25_05575	ENOG4108Q5Y	Membrane
A6K25_05585	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A6K25_05590	ENOG4105E98	transcriptional regulator DeoR family
A6K25_05595	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A6K25_05620	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A6K25_05625	ENOG4107ENK	receptor
A6K25_05640	ENOG4105CKI	cobalamin synthesis protein
A6K25_05660	ENOG4108I0Y	(ABC) transporter
A6K25_05670	ENOG4105DEN	Luciferase family
A6K25_05685	ENOG4105BZU	Histidine kinase
A6K25_05695	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A6K25_05700	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
A6K25_05705	ENOG4105JQN	Transcriptional regulator
A6K25_05725	ENOG4105CEP	NADH dehydrogenase
A6K25_05730	ENOG4108YYC	ycei family
A6K25_05735	ENOG4105DS1	cytochrome b561
A6K25_05760	ENOG4108MUZ	hydrolase
A6K25_05765	ENOG4108YZN	class I peptide chain release factor
A6K25_05810	ENOG4105VDW	Csbd family
A6K25_05850	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
A6K25_05875	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A6K25_05910	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_05920	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A6K25_05925	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A6K25_05935	ENOG4108JJ9	ABC, transporter
A6K25_05940	ENOG4108JJ8	(ABC) transporter
A6K25_05945	ENOG4107ZSV	Receptor
A6K25_05980	ENOG4105PGM	cation diffusion facilitator family transporter
A6K25_05985	ENOG4107RUZ	Sss sodium solute transporter superfamily
A6K25_06000	ENOG4105FDP	GntR family transcriptional regulator
A6K25_06010	ENOG4106IBS	oxygenase
A6K25_06015	ENOG4105HMI	Membrane
A6K25_06040	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A6K25_06050	ENOG4107R4I	Periplasmic binding protein
A6K25_06055	ENOG4105EHG	Permease protein
A6K25_06060	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A6K25_06075	ENOG4105CT4	transporter
A6K25_06080	ENOG41060NJ	transcriptional regulator
A6K25_06085	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_06090	ENOG4105BZU	Histidine kinase
A6K25_06095	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
A6K25_06105	ENOG4105BZU	Histidine kinase
A6K25_06110	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A6K25_06115	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A6K25_06120	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A6K25_06135	ENOG4108RPX	mosc domain containing protein
A6K25_06160	ENOG4105CDU	Replicative dna helicase
A6K25_06165	ENOG4105CDV	Ompa motb domain protein
A6K25_06170	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A6K25_06180	ENOG4105MYN	Zinc uptake regulation protein
A6K25_06185	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
A6K25_06190	ENOG4105E09	nadh pyrophosphatase
A6K25_06195	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A6K25_06205	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A6K25_06210	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A6K25_06215	ENOG4105K8N	protein family UPF0079, ATPase
A6K25_06220	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A6K25_06225	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A6K25_06230	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A6K25_06235	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A6K25_06240	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A6K25_06245	ENOG4107QJR	hflk protein
A6K25_06250	ENOG4105EPW	hflc protein
A6K25_06255	ENOG4105CFC	Transporter
A6K25_06260	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A6K25_06270	ENOG4105C7K	acetolactate synthase
A6K25_06285	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A6K25_06290	ENOG4107IFA	Lipase (EC 3.1.1.3)
A6K25_06305	ENOG4105CYM	Glutathione S-transferase
A6K25_06320	ENOG4105D7K	pfkb domain protein
A6K25_06330	ENOG4107T0X	DNA ligase
A6K25_06340	ENOG4107QRT	dEAD DEAH box helicase
A6K25_06345	ENOG41068D6	Glycosyltransferase
A6K25_06365	ENOG4105DWY	Agmatine deiminase
A6K25_06370	ENOG4106B0W	Curli production assembly transport component CsgG
A6K25_06380	ENOG4107Y60	(LipO)protein
A6K25_06385	ENOG4105EUJ	GTP cyclohydrolase i
A6K25_06395	ENOG4107QW3	Sucrose phosphorylase
A6K25_06400	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
A6K25_06405	ENOG4107QM2	Aldo Keto reductase
A6K25_06410	ENOG4105QNF	Outer membrane lipoprotein
A6K25_06420	ENOG4105EKE	dihydroorotase
A6K25_06425	ENOG4105C1J	atp-dependent rna helicase
A6K25_06435	ENOG4105C9K	Endothelin-converting enzyme 1
A6K25_06440	ENOG4105JSC	dimethylmenaquinone methyltransferase
A6K25_06445	ENOG4105BZ1	(ABC) transporter
A6K25_06455	ENOG4105PM1	preprotein translocase subunit SecE
A6K25_06460	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A6K25_06465	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A6K25_06470	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A6K25_06475	ENOG4108VZM	50s ribosomal protein L10
A6K25_06480	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A6K25_06485	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6K25_06490	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6K25_06495	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A6K25_06500	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A6K25_06505	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A6K25_06510	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6K25_06565	ENOG4105D22	carbon starvation protein
A6K25_06570	ENOG4108PJD	permease
A6K25_06590	ENOG4107E2E	PKHD-type hydroxylase
A6K25_06595	ENOG4108ESX	Receptor
A6K25_06600	ENOG4105EB3	Histidine kinase
A6K25_06605	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A6K25_06610	ENOG4105DA5	(ABC) transporter
A6K25_06615	ENOG4105E3A	(ABC) transporter
A6K25_06625	ENOG4108M8H	domain protein
A6K25_06630	ENOG4105DY8	decarboxylase
A6K25_06635	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A6K25_06640	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A6K25_06645	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6K25_06650	ENOG4105DJ0	Poly(A) Polymerase
A6K25_06655	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A6K25_06660	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A6K25_06665	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A6K25_06670	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6K25_06680	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
A6K25_06690	ENOG4106H78	methyltransferase
A6K25_06695	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A6K25_06700	ENOG4105CAK	Cell division ATP-binding protein ftsE
A6K25_06705	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A6K25_06710	ENOG4105D58	Diguanylate phosphodiesterase
A6K25_06715	ENOG4105D58	Diguanylate phosphodiesterase
A6K25_06720	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6K25_06725	ENOG4105SUU	thioesterase domain
A6K25_06730	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A6K25_06750	ENOG4107S2Z	UPF0761 membrane protein
A6K25_06755	ENOG4105SYT	Methylenetetrahydrofolate reductase
A6K25_06760	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
A6K25_06765	ENOG4105C6K	Malic enzyme
A6K25_06775	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A6K25_06780	ENOG4105C25	Primosomal protein n'
A6K25_06785	ENOG41063M6	Cell Division Protein
A6K25_06790	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A6K25_06795	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A6K25_06815	ENOG4108JJA	ABC, transporter
A6K25_06830	ENOG4107RE3	peptidase, S41
A6K25_06835	ENOG4107QY8	reductase
A6K25_06840	ENOG4105DC8	reductase
A6K25_06845	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_06850	ENOG4105BZU	Histidine kinase
A6K25_06860	ENOG4107Z9R	response regulator
A6K25_06865	ENOG4105DGW	oligopeptidase A
A6K25_06885	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A6K25_06890	ENOG4105VEQ	Cold shock protein
A6K25_06905	ENOG4108XM1	transcriptional regulator AsnC family
A6K25_06910	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_06915	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A6K25_06920	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A6K25_06940	ENOG4107VAM	peptidase, m28
A6K25_06945	ENOG4107QK7	reductase
A6K25_06950	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A6K25_06960	ENOG4108UV7	flagellar protein motX
A6K25_06975	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A6K25_06980	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A6K25_06985	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A6K25_07000	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A6K25_07005	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A6K25_07010	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A6K25_07015	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A6K25_07020	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A6K25_07025	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A6K25_07030	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A6K25_07035	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A6K25_07040	ENOG4105VPB	50S ribosomal protein L30
A6K25_07045	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A6K25_07050	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A6K25_07055	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A6K25_07060	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A6K25_07065	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A6K25_07070	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A6K25_07075	ENOG4108ZT0	50S ribosomal protein l17
A6K25_07080	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
A6K25_07100	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A6K25_07175	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A6K25_07180	ENOG4105K64	Glycosyl transferase, family 2
A6K25_07185	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A6K25_07195	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A6K25_07200	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A6K25_07205	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A6K25_07210	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A6K25_07230	ENOG41063Z6	transcriptional regulator, lysR family
A6K25_07290	ENOG4105D4A	Cell wall formation (By similarity)
A6K25_07295	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A6K25_07300	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
A6K25_07325	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A6K25_07335	ENOG4105CH6	catalase
A6K25_07350	ENOG4105CPC	Aldo Keto reductase
A6K25_07360	ENOG4105E54	alpha-amylase
A6K25_07370	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A6K25_07385	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6K25_07395	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6K25_07415	ENOG4107QN1	sodium solute
A6K25_07420	ENOG4105C2X	Arabinose 5-phosphate isomerase
A6K25_07430	ENOG4105BZU	Histidine kinase
A6K25_07445	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
A6K25_07455	ENOG4105D9N	nucleoside
A6K25_07460	ENOG4105DBI	uridine monophosphokinase
A6K25_07475	ENOG4108KPZ	tonB-dependent Receptor
A6K25_07490	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
A6K25_07495	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A6K25_07505	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A6K25_07510	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A6K25_07515	ENOG4105RKW	reductase (By
A6K25_07525	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6K25_07530	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6K25_07535	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6K25_07540	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
A6K25_07545	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
A6K25_07550	ENOG4105CJ2	(LipO)protein
A6K25_07560	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A6K25_07570	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A6K25_07585	ENOG4108YXU	transcriptional regulator AsnC family
A6K25_07600	ENOG4105E7A	Glutamine amidotransferase
A6K25_07605	ENOG4108WAV	Transcriptional regulator
A6K25_07615	ENOG4105C5X	domain protein
A6K25_07620	ENOG4105EFZ	amidohydrolase
A6K25_07630	ENOG4105BZU	Histidine kinase
A6K25_07635	ENOG4105KWG	Pfam:DUF1696
A6K25_07645	ENOG4105K4T	epimerase
A6K25_07650	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
A6K25_07680	ENOG4105EJG	cellulose synthase
A6K25_07690	ENOG4109015	Biopolymer transport protein exbD tolR
A6K25_07700	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
A6K25_07715	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A6K25_07730	ENOG4105C8J	)-transporter
A6K25_07735	ENOG4108535	NAD dependent epimerase/dehydratase family
A6K25_07750	ENOG4105CUY	Mechanosensitive ion channel
A6K25_07755	ENOG4106HNH	Acyl-transferase
A6K25_07760	ENOG4106HNH	Acyl-transferase
A6K25_07765	ENOG4105C4W	S-formylglutathione hydrolase
A6K25_07770	ENOG4105BZU	Histidine kinase
A6K25_07790	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A6K25_07800	ENOG41087YS	Phage shock protein A
A6K25_07825	ENOG4107ZSV	Receptor
A6K25_07830	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A6K25_07835	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A6K25_07840	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A6K25_07850	ENOG4105BZU	Histidine kinase
A6K25_07855	ENOG4108RG0	uracil-dna glycosylase
A6K25_07865	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
A6K25_07880	ENOG4105EJ2	Transcriptional regulator
A6K25_07885	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
A6K25_07930	ENOG4105CQ2	DNA polymerase
A6K25_07940	ENOG4105BZU	Histidine kinase
A6K25_07955	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6K25_07960	ENOG4105HF0	Membrane
A6K25_07975	ENOG4105X23	Endonuclease Exonuclease phosphatase
A6K25_07990	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A6K25_08000	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
A6K25_08010	ENOG4105EGS	Mechanosensitive ion channel
A6K25_08020	ENOG4107YCY	Transcriptional regulator
A6K25_08025	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
A6K25_08030	ENOG4108UHU	Aldolase
A6K25_08035	ENOG4105C1J	atp-dependent rna helicase
A6K25_08040	ENOG4105IDI	abc transporter atp-binding protein
A6K25_08095	ENOG4105Q36	FHA domain containing protein
A6K25_08115	ENOG4105DPW	Major facilitator superfamily MFS_1
A6K25_08120	ENOG4105M5J	Cupin 2, conserved barrel domain protein
A6K25_08125	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A6K25_08160	ENOG4105CA0	peroxidase
A6K25_08165	ENOG4105PE1	Receptor
A6K25_08195	ENOG4105BZU	Histidine kinase
A6K25_08200	ENOG4105WH1	Two component transcriptional regulator luxr family
A6K25_08205	ENOG4105C26	Dehydrogenase
A6K25_08220	ENOG4105BZU	Histidine kinase
A6K25_08250	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A6K25_08255	ENOG4106URE	pyrroloquinoline quinone biosynthesis protein d
A6K25_08260	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
A6K25_08265	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
A6K25_08270	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6K25_08300	ENOG4105DZG	Dehydrogenase
A6K25_08310	ENOG4105BZU	Histidine kinase
A6K25_08315	ENOG4105BZU	Histidine kinase
A6K25_08340	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A6K25_08345	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
A6K25_08355	ENOG4105BZU	Histidine kinase
A6K25_08415	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A6K25_08420	ENOG4105BZU	Histidine kinase
A6K25_08440	ENOG4105CDV	Ompa motb domain protein
A6K25_08495	ENOG4108WBH	protein TIM barrel
A6K25_08505	ENOG4105CEY	Amp-dependent synthetase and ligase
A6K25_08515	ENOG4105DUU	IucA IucC family protein
A6K25_08555	ENOG4105K6V	RNA polymerase
A6K25_08565	ENOG4108K5H	permease YjgP YjgQ family protein
A6K25_08570	ENOG4108M8S	permease YjgP YjgQ family protein
A6K25_08575	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A6K25_08580	ENOG4105MYG	DNA polymerase iii, chi subunit
A6K25_08585	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A6K25_08590	ENOG4105BZU	Histidine kinase
A6K25_08600	ENOG4105BZU	Histidine kinase
A6K25_08610	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
A6K25_08615	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
A6K25_08620	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6K25_08625	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_08630	ENOG4105CUX	Signal transduction histidine kinase
A6K25_08640	ENOG4105C5F	glutamine synthetase
A6K25_08655	ENOG4105C87	Aminotransferase class I and II
A6K25_08660	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
A6K25_08675	ENOG4108YXA	Membrane
A6K25_08695	ENOG4105C9Q	fumarate hydratase class II
A6K25_08700	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
A6K25_08705	ENOG4107QMS	site-determining protein
A6K25_08710	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
A6K25_08715	ENOG4105CSR	polyphosphate kinase 2
A6K25_08720	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A6K25_08725	ENOG4108U78	Glutathione S-transferase
A6K25_08730	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A6K25_08740	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6K25_08745	ENOG4105TW1	Carbohydrate-selective porin OprB
A6K25_08750	ENOG4105EDR	glucose galactose transporter
A6K25_08770	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A6K25_08775	ENOG4105DR5	peptidase
A6K25_08780	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A6K25_08795	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A6K25_08810	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A6K25_08825	ENOG4108J20	pectate lyase
A6K25_08845	ENOG4108J20	pectate lyase
A6K25_08850	ENOG4105VZ8	Transcriptional regulator
A6K25_08860	ENOG4105BZ8	glutamate synthase
A6K25_08865	ENOG4105CBC	glutamate synthase
A6K25_08870	ENOG4105BZU	Histidine kinase
A6K25_08915	ENOG4105BZU	Histidine kinase
A6K25_08920	ENOG4105C7F	AcnD-accessory protein PrpF
A6K25_08925	ENOG4108I0Z	Aconitate hydratase
A6K25_08930	ENOG4105BZN	citrate synthase
A6K25_08935	ENOG4105CR4	methylisocitrate lyase
A6K25_08955	ENOG4108ZGX	Histidine kinase
A6K25_09000	ENOG4105W4M	Transport-associated protein
A6K25_09005	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A6K25_09010	ENOG41082RQ	UPF0102 protein
A6K25_09015	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
A6K25_09020	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A6K25_09035	ENOG4105E3Q	saccharopine dehydrogenase
A6K25_09065	ENOG4105BZU	Histidine kinase
A6K25_09070	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A6K25_09075	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
A6K25_09080	ENOG4107YTP	response regulator receiver protein
A6K25_09085	ENOG4105D6J	arsenicaL-resistance protein
A6K25_09090	ENOG4105CAU	Arsenical resistance protein, ArsH
A6K25_09100	ENOG41082YX	Transcriptional regulator, arsr family
A6K25_09120	ENOG4105BZU	Histidine kinase
A6K25_09125	ENOG4105WH1	Two component transcriptional regulator luxr family
A6K25_09135	ENOG4105CC0	LysR family Transcriptional regulator
A6K25_09145	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A6K25_09155	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A6K25_09160	ENOG4107QP8	phosphohexose isomerase
A6K25_09165	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A6K25_09170	ENOG4105D1Q	UPF0246 protein
A6K25_09175	ENOG4108K3A	Glutathione S-transferase
A6K25_09180	ENOG4108Z7R	Chaperone CsaA
A6K25_09195	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6K25_09210	ENOG4108VIA	integral membrane protein
A6K25_09215	ENOG4105II7	pyrroline-5-carboxylate reductase
A6K25_09220	ENOG4105DFA	alanine racemase domain protein
A6K25_09225	ENOG4105CZX	twitching motility protein
A6K25_09230	ENOG4105CZX	twitching motility protein
A6K25_09240	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A6K25_09245	ENOG4108UJU	UPF0301 protein
A6K25_09250	ENOG4105D7Z	glutathione synthase
A6K25_09255	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A6K25_09260	ENOG4105D64	Mechanosensitive ion channel
A6K25_09280	ENOG4105BZU	Histidine kinase
A6K25_09285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_09300	ENOG4105EHV	domain protein
A6K25_09330	ENOG4108IGT	Dipeptidase
A6K25_09340	ENOG4108V6E	Cell division protein mraZ
A6K25_09345	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A6K25_09350	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
A6K25_09355	ENOG4105CJN	penicillin-binding protein
A6K25_09360	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A6K25_09365	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A6K25_09370	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A6K25_09375	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A6K25_09380	ENOG4105CNI	cell division protein FtsW
A6K25_09385	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A6K25_09390	ENOG4105DFU	Cell wall formation (By similarity)
A6K25_09395	ENOG4105CPF	Cell wall formation (By similarity)
A6K25_09400	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
A6K25_09405	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A6K25_09410	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A6K25_09415	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6K25_09420	ENOG4105DR5	peptidase
A6K25_09425	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A6K25_09430	ENOG4105M6F	mutator MutT protein
A6K25_09435	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
A6K25_09440	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
A6K25_09445	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
A6K25_09460	ENOG4105D7Q	type ii secretion system
A6K25_09465	ENOG4108ZUW	Major pilin subunit
A6K25_09470	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A6K25_09490	ENOG41073TP	transcriptional regulator
A6K25_09495	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A6K25_09500	ENOG4107QSN	dihydrolipoamide acetyltransferase
A6K25_09505	ENOG4107QN2	dihydrolipoyl dehydrogenase
A6K25_09545	ENOG4105XZD	Fe-S protein
A6K25_09565	ENOG4108JQ1	Dehydrogenase
A6K25_09570	ENOG4105E66	phosphoriboisomerase A
A6K25_09575	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
A6K25_09585	ENOG4105DU0	nucleoside hydrolase
A6K25_09590	ENOG4108RVA	ribokinase
A6K25_09605	ENOG4107RAQ	aminopeptidase
A6K25_09610	ENOG4105D0A	hydroxylase
A6K25_09615	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A6K25_09630	ENOG4105DC7	peptidase M24
A6K25_09640	ENOG4105C27	TonB-dependent Receptor Plug
A6K25_09655	ENOG4108HKT	sucrose-6-phosphate hydrolase
A6K25_09660	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
A6K25_09665	ENOG4106NDP	Transcriptional regulator
A6K25_09680	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A6K25_09685	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A6K25_09690	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6K25_09715	ENOG4106H3A	restriction
A6K25_09765	ENOG4105CV8	reductase
A6K25_09775	ENOG4105F27	Major Facilitator
A6K25_09825	ENOG4105C1J	atp-dependent rna helicase
A6K25_09830	ENOG4108594	Permease of the drug metabolite transporter
A6K25_09860	ENOG4105DFD	Na H antiporter
A6K25_09890	ENOG4108VKG	metal-dependent hydrolase
A6K25_09910	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A6K25_09925	ENOG4108HMN	Caspase domain
A6K25_09950	ENOG4108JUA	Transcriptional regulator
A6K25_09965	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A6K25_09970	ENOG4105DVC	DnaJ domain protein
A6K25_09980	ENOG4105ETT	transcriptional Regulator, LysR family
A6K25_10000	ENOG4108VWS	Yaeq family
A6K25_10005	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A6K25_10015	ENOG4107U9T	Pfam:Ribonuclease_BN
A6K25_10025	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
A6K25_10030	ENOG4105Y49	secretion protein, HlyD family
A6K25_10050	ENOG4107RNH	Outer membrane receptor FepA
A6K25_10060	ENOG4108JU7	Transcriptional regulator
A6K25_10065	ENOG4107ZSV	Receptor
A6K25_10085	ENOG4107U7N	hydantoinase B oxoprolinase
A6K25_10090	ENOG4108UAU	isochorismatase
A6K25_10095	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6K25_10100	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A6K25_10130	ENOG4105W1Y	Transcriptional regulator
A6K25_10135	ENOG4105PGM	cation diffusion facilitator family transporter
A6K25_10145	ENOG4105PGM	cation diffusion facilitator family transporter
A6K25_10175	ENOG4105IYK	transposase
A6K25_10180	ENOG4105DQ6	Transposase
A6K25_10200	ENOG4108Z0Z	intracellular protease Pfpi family
A6K25_10205	ENOG4105EMU	Dehydrogenase
A6K25_10210	ENOG4105JQN	Transcriptional regulator
A6K25_10235	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A6K25_10240	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
A6K25_10245	ENOG4105CCU	oxidase (Subunit III)
A6K25_10250	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A6K25_10255	ENOG4105E2S	oxidase) subunit II
A6K25_10265	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A6K25_10300	ENOG4105KSC	Transcriptional regulator, TraR DksA family
A6K25_10315	ENOG4105KVH	Transcriptional regulator
A6K25_10320	ENOG4105CHR	reductase
A6K25_10335	ENOG4105ETT	transcriptional Regulator, LysR family
A6K25_10360	ENOG4105C57	major facilitator superfamily
A6K25_10400	ENOG4105CFP	Peptidase U32
A6K25_10405	ENOG4108S4H	thioesterase Superfamily protein
A6K25_10415	ENOG4107T0K	Adenylate cyclase
A6K25_10420	ENOG4108RCM	Nitroreductase
A6K25_10430	ENOG4107XDR	Lactoylglutathione lyase
A6K25_10455	ENOG4105D6Z	AFG1 family ATPase
A6K25_10465	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6K25_10480	ENOG4105CNM	Receptor
A6K25_10485	ENOG4108IGT	Dipeptidase
A6K25_10495	ENOG4105CSU	acyl-Coa dehydrogenase
A6K25_10535	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A6K25_10550	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6K25_10565	ENOG4108Z4X	TRANSCRIPTIONal
A6K25_10570	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
A6K25_10600	ENOG41060NJ	transcriptional regulator
A6K25_10625	ENOG4108Z12	YiaAB two helix domain-containing protein
A6K25_10630	ENOG4107RBR	Receptor
A6K25_10645	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A6K25_10655	ENOG4108VN5	Inherit from COG: PepSY-associated TM helix
A6K25_10660	ENOG4105E0K	tonB-dependent siderophore receptor
A6K25_10680	ENOG4105CXN	decarboxylase
A6K25_10715	ENOG4105DZ0	fad dependent oxidoreductase
A6K25_10720	ENOG4108Z4U	Ferredoxin
A6K25_10725	ENOG4108RWN	rrna methyltransferase
A6K25_10730	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A6K25_10770	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A6K25_10785	ENOG4107104	thymidine kinase
A6K25_10790	ENOG4105BZU	Histidine kinase
A6K25_10800	ENOG4107QPN	acyl-Coa dehydrogenase
A6K25_10830	ENOG4105D1S	lipid A biosynthesis
A6K25_10850	ENOG41082IR	Excinuclease ABC C subunit domain protein
A6K25_10855	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A6K25_10870	ENOG4108QV3	biosynthesis protein
A6K25_10885	ENOG4105D3Q	Sugar transferase
A6K25_10905	ENOG4105K64	Glycosyl transferase, family 2
A6K25_10950	ENOG4105CPK	Glycosyl transferase (Group 1
A6K25_10955	ENOG4107T8Q	Glycosyl transferase (Group 1
A6K25_10970	ENOG4107QZ7	Cellulose synthase catalytic subunit
A6K25_10975	ENOG4105D7W	serine acetyltransferase
A6K25_10980	ENOG4105CUZ	uba thif-type nad fad binding protein
A6K25_11025	ENOG4107RET	Isocitrate lyase
A6K25_11035	ENOG4105G6Z	alkaline phosphatase
A6K25_11040	ENOG4105CSV	Glutaminase
A6K25_11055	ENOG4106032	Glutathionylspermidine synthase
A6K25_11080	ENOG4108P9J	Phage shock protein A
A6K25_11085	ENOG4105FUX	Conserved Protein
A6K25_11095	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A6K25_11100	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A6K25_11105	ENOG4105VIE	preprotein translocase, subunit YajC
A6K25_11110	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6K25_11115	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A6K25_11130	ENOG4105BZU	Histidine kinase
A6K25_11150	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A6K25_11165	ENOG4105C3J	Cysteine desulfurase
A6K25_11175	ENOG4105C3K	feS assembly ATPase SufC
A6K25_11180	ENOG4105JRK	feS assembly protein SufD
A6K25_11185	ENOG4105C9B	Cysteine desulfurase
A6K25_11190	ENOG4108Z4V	iron-sulfur cluster assembly
A6K25_11200	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A6K25_11205	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A6K25_11210	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A6K25_11225	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A6K25_11230	ENOG4105CUT	histidyl-tRNA synthetase
A6K25_11235	ENOG4105N21	Membrane
A6K25_11240	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6K25_11245	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A6K25_11255	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6K25_11260	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A6K25_11265	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A6K25_11275	ENOG4108NVR	Methyl-accepting chemotaxis
A6K25_11280	ENOG4105DGU	Histone deacetylase
A6K25_11285	ENOG4105HDD	phospholipase
A6K25_11295	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A6K25_11300	ENOG4108R96	Methyltransferase, YaeB family
A6K25_11310	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A6K25_11340	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A6K25_11345	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A6K25_11350	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A6K25_11355	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A6K25_11360	ENOG4105K70	DNA-binding protein
A6K25_11365	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
A6K25_11370	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A6K25_11390	ENOG4105C09	Bile acid
A6K25_11395	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A6K25_11410	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A6K25_11415	ENOG4105CJR	Integral membrane protein (MviN
A6K25_11420	ENOG4105DTN	riboflavin biosynthesis protein ribF
A6K25_11425	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A6K25_11430	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A6K25_11435	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A6K25_11440	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A6K25_11500	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
A6K25_11505	ENOG4108YZA	Nitrogen regulatory protein pii
A6K25_11510	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A6K25_11515	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A6K25_11520	ENOG4105Y75	tpr repeat protein
A6K25_11535	ENOG4108IYU	L-aspartate oxidase
A6K25_11540	ENOG4105EMN	RNA polymerase sigma factor
A6K25_11560	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A6K25_11565	ENOG4105C3F	Signal peptidase i
A6K25_11580	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A6K25_11585	ENOG4105EYA	deoxyribonuclease
A6K25_11595	ENOG4105EAC	phosphoserine phosphatase
A6K25_11605	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A6K25_11615	ENOG4105C5H	ABC transporter
A6K25_11620	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6K25_11625	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A6K25_11630	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A6K25_11635	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A6K25_11650	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A6K25_11655	ENOG4107YIM	Involved in the transcription termination process (By similarity)
A6K25_11660	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A6K25_11665	ENOG4108ZAI	phosphatidylglycerophosphatase a
A6K25_11670	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A6K25_11675	ENOG4105CTB	Polyprenyl synthetase
A6K25_11680	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A6K25_11685	ENOG4105E14	MotA TolQ exbB proton channel
A6K25_11690	ENOG4106VK6	Flagellar motor protein
A6K25_11695	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A6K25_11710	ENOG4105EMU	Dehydrogenase
A6K25_11725	ENOG4105K6V	RNA polymerase
A6K25_11735	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6K25_11740	ENOG4105C34	Pseudouridine synthase
A6K25_11745	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A6K25_11750	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6K25_11770	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A6K25_11825	ENOG4108HMN	Caspase domain
A6K25_11835	ENOG4105E18	UPF0276 protein
A6K25_11845	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A6K25_11850	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A6K25_11855	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A6K25_11875	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A6K25_11880	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A6K25_11885	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A6K25_11900	ENOG4105C3F	Signal peptidase i
A6K25_11905	ENOG4105C5X	domain protein
A6K25_11915	ENOG4105DHQ	Histidine kinase
A6K25_11945	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A6K25_11955	ENOG4108IQE	Amp-dependent synthetase and ligase
A6K25_11965	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
A6K25_11975	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A6K25_11980	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A6K25_11985	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A6K25_11990	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A6K25_11995	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A6K25_12000	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6K25_12005	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A6K25_12010	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A6K25_12070	ENOG4105DVT	helicase
A6K25_12075	ENOG41072GX	Peptidase M22 Glycoprotease
A6K25_12090	ENOG410832A	alpha/beta hydrolase fold
A6K25_12095	ENOG4105CEY	Amp-dependent synthetase and ligase
A6K25_12100	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
A6K25_12105	ENOG4105VNG	YcgL domain-containing protein
A6K25_12115	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
A6K25_12120	ENOG4108ZZ3	UPF0260 protein
A6K25_12125	ENOG4108428	Inherit from COG: -acetyltransferase
A6K25_12130	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
A6K25_12135	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A6K25_12140	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
A6K25_12175	ENOG4108UH6	UPF0754 membrane protein
A6K25_12180	ENOG4105U5Y	Transcriptional regulator
A6K25_12185	ENOG4105D8T	Acyltransferase
A6K25_12210	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A6K25_12275	ENOG4108BPE	-transporting atpase
A6K25_12305	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A6K25_12325	ENOG4105MP9	class II Aldolase
A6K25_12330	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
A6K25_12345	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A6K25_12350	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A6K25_12360	ENOG4108S3P	Sporulation domain protein
A6K25_12365	ENOG4105E96	Colicin v production protein
A6K25_12370	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A6K25_12380	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
A6K25_12385	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
A6K25_12395	ENOG4105CIS	alcohol dehydrogenase
A6K25_12400	ENOG4105EY3	heparinase II III family protein
A6K25_12405	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
A6K25_12410	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
A6K25_12415	ENOG4105C7W	Xanthine dehydrogenase
A6K25_12420	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A6K25_12440	ENOG4107S78	Band 7 protein
A6K25_12455	ENOG4105G6Z	alkaline phosphatase
A6K25_12460	ENOG4105G6Z	alkaline phosphatase
A6K25_12470	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6K25_12475	ENOG4105C8N	cysteinyl-tRNA synthetase
A6K25_12490	ENOG4105E9H	Lytic Murein transglycosylase
A6K25_12495	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A6K25_12500	ENOG4105D1A	Methyltransferase
A6K25_12505	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A6K25_12510	ENOG4105D1F	ATP-binding protein
A6K25_12515	ENOG4105DHP	deoxycytidine triphosphate deaminase
A6K25_12520	ENOG4105C8P	)-transporter
A6K25_12540	ENOG4108RCM	Nitroreductase
A6K25_12570	ENOG4105CH6	catalase
A6K25_12580	ENOG4105C8Q	Methyl-accepting chemotaxis
A6K25_12600	ENOG4107RF4	Phosphodiesterase
A6K25_12610	ENOG4106DTQ	Protein TsgA homolog
A6K25_12620	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A6K25_12645	ENOG4105BZU	Histidine kinase
A6K25_12650	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A6K25_12660	ENOG4105BZU	Histidine kinase
A6K25_12665	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A6K25_12675	ENOG4108Z9K	Osmotically inducible protein
A6K25_12690	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A6K25_12705	ENOG4105BZU	Histidine kinase
A6K25_12720	ENOG4105CK5	oxidoreductase
A6K25_12725	ENOG4105CXK	mandelate racemase muconate lactonizing
A6K25_12760	ENOG4108K8S	endonuclease I
A6K25_12780	ENOG4105NBR	Pectinesterase
A6K25_12790	ENOG4107XII	Glycosyl Hydrolase Family 88
A6K25_12800	ENOG4107TDE	lipolytic protein G-D-S-L family
A6K25_12805	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
A6K25_12810	ENOG4105DEI	Mannitol dehydrogenase
A6K25_12815	ENOG4105D2H	Uronic isomerase
A6K25_12820	ENOG4105CTX	dehydratase
A6K25_12830	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A6K25_12840	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
A6K25_12845	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
A6K25_12850	ENOG4105CHR	reductase
A6K25_12860	ENOG4105EIG	urea carboxylase-associated protein 1
A6K25_12885	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A6K25_12890	ENOG4105EB3	Histidine kinase
A6K25_12935	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
A6K25_12940	ENOG4105CA9	Pyruvate kinase
A6K25_12945	ENOG4106KNT	transcriptional regulator
A6K25_12950	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A6K25_12955	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
A6K25_12960	ENOG4105C01	Dihydroxy-acid dehydratase
A6K25_12965	ENOG4105CHC	glucokinase (EC 2.7.1.2)
A6K25_12970	ENOG4108UHU	Aldolase
A6K25_12975	ENOG4105DSB	aldose 1-epimerase
A6K25_12985	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
A6K25_12990	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
A6K25_13000	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A6K25_13005	ENOG4105E0X	reductase
A6K25_13025	ENOG4105BZG	amino acid carrier protein
A6K25_13035	ENOG4105VUT	cytoplasmic protein
A6K25_13060	ENOG4105DK2	UPF0207 protein
A6K25_13085	ENOG4105BZU	Histidine kinase
A6K25_13105	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_13115	ENOG4107RSM	transcriptional regulator
A6K25_13125	ENOG41082SX	arsR family transcriptional regulator
A6K25_13145	ENOG4105CVI	Transcriptional regulator
A6K25_13160	ENOG4108YXG	UPF0502 protein
A6K25_13170	ENOG4105BZU	Histidine kinase
A6K25_13175	ENOG4108IQE	Amp-dependent synthetase and ligase
A6K25_13185	ENOG4105DSY	exodeoxyribonuclease V, gamma
A6K25_13190	ENOG4107QKA	exodeoxyribonuclease V beta
A6K25_13195	ENOG4107QYX	exodeoxyribonuclease v alpha
A6K25_13210	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A6K25_13225	ENOG4105EG6	Saccharopine dehydrogenase
A6K25_13230	ENOG4105CHM	Aminotransferase
A6K25_13240	ENOG4105BZU	Histidine kinase
A6K25_13265	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A6K25_13585	ENOG4105D06	uba thif-type nad fad binding protein
A6K25_13590	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
A6K25_13595	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6K25_13600	ENOG4105M00	molybdopterin converting factor, subunit 1
A6K25_13605	ENOG4108ZAF	Molybdopterin
A6K25_13610	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A6K25_13615	ENOG4105E0C	molybdate abc transporter
A6K25_13620	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A6K25_13625	ENOG4105D4P	Coproporphyrinogen iii oxidase
A6K25_13655	ENOG4105C1G	acyl-Coa dehydrogenase
A6K25_13685	ENOG4108J2P	Alpha beta hydrolase fold
A6K25_13690	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A6K25_13695	ENOG4105CHU	acetyl-coa acetyltransferase
A6K25_13700	ENOG4105CSU	acyl-Coa dehydrogenase
A6K25_13705	ENOG4105D74	hydrolase
A6K25_13720	ENOG4105DKT	Transcriptional regulator
A6K25_13725	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
A6K25_13735	ENOG4105DEI	Mannitol dehydrogenase
A6K25_13755	ENOG4105D64	Mechanosensitive ion channel
A6K25_13775	ENOG4105D8X	mechanosensitive ion channel
A6K25_13780	ENOG4105D05	Receptor
A6K25_13785	ENOG4105KZX	Pterin carbinolamine dehydratase
A6K25_13800	ENOG4105BZU	Histidine kinase
A6K25_13805	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6K25_13810	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
A6K25_13815	ENOG4105CHV	Transcription elongation factor NusA
A6K25_13820	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A6K25_13825	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A6K25_13830	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A6K25_13835	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A6K25_13840	ENOG4108M3P	Membrane
A6K25_13850	ENOG4105BZU	Histidine kinase
A6K25_13855	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
A6K25_13865	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A6K25_13890	ENOG4105D3R	alkyl hydroperoxide reductase
A6K25_13900	ENOG4105E0K	tonB-dependent siderophore receptor
A6K25_13925	ENOG4105CCT	upf0313 protein
A6K25_13940	ENOG4105D05	Receptor
A6K25_13955	ENOG4105VNH	ABC transporter solute-binding protein
A6K25_13960	ENOG4105CXZ	ABC transporter, permease
A6K25_13965	ENOG4108VGW	abc transporter atp-binding protein
A6K25_13970	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
A6K25_14035	ENOG4105E0K	tonB-dependent siderophore receptor
A6K25_14065	ENOG4105C26	Dehydrogenase
A6K25_14070	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
A6K25_14095	ENOG4105F27	Major Facilitator
A6K25_14100	ENOG4105D05	Receptor
A6K25_14115	ENOG410679B	prophage CP4-57 regulatory protein alpA
A6K25_14145	ENOG4105DFP	Integrase
A6K25_14160	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A6K25_14165	ENOG4108Z1B	Cyclase dehydrase
A6K25_14170	ENOG4105VDB	UPF0125 protein
A6K25_14180	ENOG4105C94	Transporter
A6K25_14190	ENOG4107RDJ	Sulfotransferase
A6K25_14200	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A6K25_14205	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A6K25_14210	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
A6K25_14220	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
A6K25_14240	ENOG4105UHE	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A6K25_14260	ENOG4107UWP	Major facilitator superfamily MFS_1
A6K25_14285	ENOG4107ZT6	cytidine deaminase
A6K25_14305	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A6K25_14310	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
A6K25_14315	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A6K25_14330	ENOG4105BZ1	(ABC) transporter
A6K25_14335	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A6K25_14340	ENOG4105W49	UPF0434 protein
A6K25_14345	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A6K25_14350	ENOG4105CHR	reductase
A6K25_14355	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A6K25_14375	ENOG4105CUZ	uba thif-type nad fad binding protein
A6K25_14380	ENOG4105D5U	fad dependent oxidoreductase
A6K25_14385	ENOG4105CHF	Glutathione S-transferase
A6K25_14390	ENOG4107QKV	phosphomannomutase
A6K25_14400	ENOG4105BZN	citrate synthase
A6K25_14405	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
A6K25_14410	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
A6K25_14415	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A6K25_14420	ENOG4105E33	succinate dehydrogenase
A6K25_14425	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A6K25_14430	ENOG4105C7S	Dehydrogenase
A6K25_14435	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A6K25_14440	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A6K25_14450	ENOG4105QV4	Tryptophan halogenase
A6K25_14465	ENOG4108NRW	Phospholipase, patatin family
A6K25_14485	ENOG4108IUK	alpha amylase, catalytic
A6K25_14500	ENOG4105ETE	Transcriptional regulator (LacI family
A6K25_14505	ENOG4105CX6	glutaminyL-tRNA synthetase
A6K25_14510	ENOG4105UBK	short-chain dehydrogenase reductase
A6K25_14515	ENOG4108M0H	Extracellular lipase
A6K25_14520	ENOG4107SQI	penicillin amidase
A6K25_14525	ENOG4105ERU	peptidase
A6K25_14550	ENOG4107QNR	UPF0135 protein
A6K25_14555	ENOG4106371	Methyltransferase
A6K25_14560	ENOG4105C5I	Dehydrogenase
A6K25_14565	ENOG4108V06	Glutathione peroxidase
A6K25_14570	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A6K25_14580	ENOG4105C1G	acyl-Coa dehydrogenase
A6K25_14585	ENOG4108UKI	Enoyl-CoA hydratase
A6K25_14590	ENOG4105DHI	Methyltransferase
A6K25_14600	ENOG4105E68	Sulfatase
A6K25_14605	ENOG4105PAN	UPF0352 protein
A6K25_14610	ENOG4106V8H	Nucleoid-associated protein
A6K25_14640	ENOG4108HRK	Histidine kinase
A6K25_14645	ENOG4108NEV	two component transcriptional regulator, LytTR family
A6K25_14650	ENOG4105CTQ	phosphohexokinase
A6K25_14660	ENOG4105BZU	Histidine kinase
A6K25_14670	ENOG4105C72	UPF0176 protein
A6K25_14680	ENOG4105FE9	pseudouridine synthase
A6K25_14765	ENOG4105C1J	atp-dependent rna helicase
A6K25_14770	ENOG4107QNJ	CoA-transferase subunit B
A6K25_14775	ENOG4105D6N	CoA-transferase, subunit a
A6K25_14780	ENOG4105F04	LysR family Transcriptional regulator
A6K25_14795	ENOG4107R11	Transcriptional regulator
A6K25_14800	ENOG4105EJQ	L-serine dehydratase
A6K25_14805	ENOG4105P8F	nudix hydrolase
A6K25_14810	ENOG4105CRQ	synthase (Component I)
A6K25_14820	ENOG4105CGY	Dna recombination protein
A6K25_14825	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
A6K25_14830	ENOG4107R0V	Pyruvate dehydrogenase
A6K25_14835	ENOG4105CPP	Dehydrogenase, E1 component
A6K25_14845	ENOG4105D6S	protein involved in catabolism of external DNA
A6K25_14855	ENOG4105C29	acyl-CoA thioesterase
A6K25_14860	ENOG4108Z0R	Transferase
A6K25_14865	ENOG4105C5R	Aminotransferase
A6K25_14885	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
A6K25_14890	ENOG4105CN1	protease
A6K25_14895	ENOG4105C8J	)-transporter
A6K25_14900	ENOG4105DFD	Na H antiporter
A6K25_14905	ENOG4105CD8	aminopeptidase N
A6K25_14920	ENOG4105D25	secreted protein
A6K25_14935	ENOG4105C7I	Dehydrogenase
A6K25_14940	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A6K25_14945	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A6K25_14955	ENOG4105C5H	ABC transporter
A6K25_14965	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
A6K25_14970	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
A6K25_14980	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A6K25_14985	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A6K25_14990	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
A6K25_15015	ENOG41080IJ	Diacylglycerol kinase
A6K25_15020	ENOG41081QV	Universal stress protein
A6K25_15030	ENOG4105CBC	glutamate synthase
A6K25_15035	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A6K25_15055	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
A6K25_15070	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
A6K25_15080	ENOG4105C59	p-type ATPase
A6K25_15095	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
A6K25_15100	ENOG4105Q9Y	Universal stress protein
A6K25_15105	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A6K25_15110	ENOG4105D78	K07001 NTE family protein
A6K25_15135	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A6K25_15140	ENOG4105KHC	sulfurtransferase
A6K25_15145	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A6K25_15150	ENOG4106IUH	DTW domain containing protein
A6K25_15235	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A6K25_15240	ENOG4105WH1	Two component transcriptional regulator luxr family
A6K25_15245	ENOG4105C2I	pirin domain protein
A6K25_15285	ENOG4105DHQ	Histidine kinase
A6K25_15290	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A6K25_15315	ENOG4108MN8	Membrane
A6K25_15320	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
A6K25_15325	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
A6K25_15335	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
A6K25_15340	ENOG4108KP7	hydrolase
A6K25_15345	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A6K25_15350	ENOG4105WMR	Protein CrcB homolog
A6K25_15355	ENOG4105D1H	recombination factor protein RarA
A6K25_15360	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A6K25_15365	ENOG4105CNU	cell division protein FtsK
A6K25_15370	ENOG4105EW9	transcriptional regulator AsnC family
A6K25_15375	ENOG4105DCF	alanine dehydrogenase
A6K25_15380	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A6K25_15385	ENOG4105CFV	Tetratricopeptide repeat protein
A6K25_15390	ENOG4105Q4A	inner membrane protein yciS
A6K25_15400	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A6K25_15405	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A6K25_15410	ENOG4105CAT	Cytidine monophosphate kinase
A6K25_15415	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A6K25_15420	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A6K25_15425	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A6K25_15435	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6K25_15440	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A6K25_15445	ENOG4105XPH	Ferredoxin
A6K25_15450	ENOG4105BZU	Histidine kinase
A6K25_15480	ENOG4107TXC	Transcriptional regulator
A6K25_15550	ENOG4107RRE	RNA-directed DNA polymerase
A6K25_15575	ENOG4105CJ1	ABC, transporter
A6K25_15590	ENOG4105E0K	tonB-dependent siderophore receptor
A6K25_15605	ENOG4105C8V	SAICAR synthetase
A6K25_15610	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6K25_15615	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A6K25_15625	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6K25_15635	ENOG4105ERG	peptidase m48, ste24p
A6K25_15645	ENOG4105K89	arsenate reductase
A6K25_15650	ENOG4105CS1	NAD(P)H quinone oxidoreductase
A6K25_15680	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A6K25_15685	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A6K25_15695	ENOG4107QPN	acyl-Coa dehydrogenase
A6K25_15710	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
A6K25_15715	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
A6K25_15720	ENOG4105DBI	uridine monophosphokinase
A6K25_15725	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
A6K25_15730	ENOG4105C3Q	Glycosyl transferase, family 2
A6K25_15740	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A6K25_15760	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A6K25_15765	ENOG4105C6T	cysteine synthase
A6K25_15775	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6K25_15780	ENOG4108UKI	Enoyl-CoA hydratase
A6K25_15795	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A6K25_15800	ENOG4105C28	cystathionine
A6K25_15815	ENOG4105CGF	Aromatic amino acid aminotransferase
A6K25_15820	ENOG4108UPT	UPF0178 protein
A6K25_15825	ENOG4105CHR	reductase
A6K25_15835	ENOG4105CSU	acyl-Coa dehydrogenase
A6K25_15840	ENOG4106HBX	Transcriptional Regulator AraC Family
A6K25_15870	ENOG4105C10	Electron transfer flavoprotein
A6K25_15875	ENOG4105BZJ	Electron transfer flavoprotein
A6K25_15880	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A6K25_15885	ENOG4108YX2	DNA-binding protein
A6K25_15890	ENOG4105EV9	Alpha Beta Hydrolase
A6K25_15900	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
A6K25_15905	ENOG4108NVR	Methyl-accepting chemotaxis
A6K25_15910	ENOG41090R7	Ferric uptake
A6K25_15915	ENOG4105C6Z	Gluconate
A6K25_15920	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A6K25_15925	ENOG4105K2J	Transcriptional regulator
A6K25_15945	ENOG4105E7W	lamb ycsf family protein
A6K25_15950	ENOG4105QNR	S1 RNA binding domain protein
A6K25_15955	ENOG4108UKZ	OsmC family
A6K25_15960	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A6K25_15985	ENOG4105CHM	Aminotransferase
A6K25_15990	ENOG4105DK2	UPF0207 protein
A6K25_15995	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A6K25_16005	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A6K25_16010	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A6K25_16015	ENOG4105W39	Membrane
A6K25_16025	ENOG4105K5B	UPF0225 protein
A6K25_16060	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
A6K25_16070	ENOG4105I4A	GCN5-related N-acetyltransferase
A6K25_16075	ENOG4105DKW	ABC transporter
A6K25_16085	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A6K25_16100	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A6K25_16110	ENOG4105CK7	Sodium proline symporter
A6K25_16130	ENOG4107TE5	Lipid kinase
A6K25_16140	ENOG4105BZU	Histidine kinase
A6K25_16155	ENOG4105CP7	Triose-phosphate isomerase
A6K25_16160	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A6K25_16165	ENOG4105EEI	dihydropteroate synthase
A6K25_16170	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A6K25_16175	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A6K25_16180	ENOG4105HBR	Rna-binding protein
A6K25_16190	ENOG4105DAN	ATP-dependent protease
A6K25_16195	ENOG4105C8T	Leucyl-tRNA synthetase
A6K25_16205	ENOG4105DJF	DNA polymerase III, delta' subunit
A6K25_16210	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A6K25_16215	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A6K25_16220	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A6K25_16225	ENOG4105CJN	penicillin-binding protein
A6K25_16230	ENOG4105CNI	cell division protein FtsW
A6K25_16235	ENOG4105K6T	rare lipoprotein A
A6K25_16240	ENOG4105DZ1	carboxypeptidase
A6K25_16245	ENOG4108Z43	UPF0250 protein
A6K25_16250	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A6K25_16255	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A6K25_16265	ENOG4105HDK	L-asparaginase
A6K25_16275	ENOG41069NU	Nitroreductase
A6K25_16290	ENOG4105D07	Signal peptide peptidase, SppA
A6K25_16295	ENOG4105GPY	SprT protein
A6K25_16300	ENOG4105PQ6	UPF0208 membrane protein
A6K25_16310	ENOG4105C3M	thioredoxin reductase
A6K25_16315	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A6K25_16320	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
A6K25_16325	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A6K25_16330	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A6K25_16335	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A6K25_16340	ENOG4105VEQ	Cold shock protein
A6K25_16345	ENOG4105E9K	Isocitrate dehydrogenase
A6K25_16350	ENOG4108R99	pseudouridine synthase
A6K25_16355	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A6K25_16360	ENOG41075W9	High frequency lysogenization protein HflD homolog
A6K25_16365	ENOG4107QTF	adenylosuccinate lyase
A6K25_16380	ENOG4105EZE	Cupin 4 family protein
A6K25_16395	ENOG4105CQB	FAD linked oxidase domain protein
A6K25_16400	ENOG4105NBK	UPF0345 protein
A6K25_16405	ENOG4105FQP	Beta-lactamase
A6K25_16465	ENOG4105DFF	Rod shape-determining protein mreb
A6K25_16490	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A6K25_16500	ENOG4105CHR	reductase
A6K25_16520	ENOG4108N2Y	auxin Efflux
A6K25_16540	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A6K25_16545	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
A6K25_16560	ENOG4108V5Q	transglutaminase-like protein
A6K25_16580	ENOG4105VQU	rdd domain containing protein
A6K25_16600	ENOG4105BZU	Histidine kinase
A6K25_16615	ENOG4105F8V	Hydrolase, tatD family
A6K25_16620	ENOG4107QRG	dna polymerase iii
A6K25_16625	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A6K25_16630	ENOG4105HHA	aminodeoxychorismate lyase
A6K25_16635	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
A6K25_16640	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A6K25_16645	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A6K25_16650	ENOG4105CHR	reductase
A6K25_16655	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A6K25_16660	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A6K25_16665	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A6K25_16670	ENOG4105VGS	50s ribosomal protein l32
A6K25_16675	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
A6K25_16680	ENOG4108UHJ	MAF-like protein
A6K25_16685	ENOG4107XGZ	Hydrolase
A6K25_16690	ENOG4105EI2	Pseudouridine synthase
A6K25_16695	ENOG4105C03	ribonuclease
A6K25_16715	ENOG4107YB6	acetyltransferase, (GNAT) family
A6K25_16725	ENOG4105EXG	Transcriptional regulator
A6K25_16750	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A6K25_16760	ENOG4108NUU	Transcriptional regulator
A6K25_16770	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A6K25_16775	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
A6K25_16790	ENOG4105D60	lipoprotein releasing system transmembrane protein
A6K25_16795	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A6K25_16800	ENOG4108M8H	domain protein
A6K25_16830	ENOG4108JDX	DNA polymerase iii, epsilon subunit
A6K25_16835	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6K25_16845	ENOG4105DR4	Methyltransferase
A6K25_16860	ENOG4105CQ7	ATP-dependent helicase
A6K25_16905	ENOG4105BZU	Histidine kinase
A6K25_16910	ENOG4105CJB	Exodeoxyribonuclease I
A6K25_16925	ENOG4105CHU	acetyl-coa acetyltransferase
A6K25_16930	ENOG4108Z6Z	Transcriptional regulator
A6K25_16935	ENOG4105C1G	acyl-Coa dehydrogenase
A6K25_16940	ENOG4107QX3	carboxylase
A6K25_16945	ENOG4105CGU	Enoyl-CoA hydratase
A6K25_16955	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A6K25_16965	ENOG4105BZU	Histidine kinase
A6K25_16980	ENOG4105DU0	nucleoside hydrolase
A6K25_16985	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A6K25_16995	ENOG4105DNH	Major Facilitator
A6K25_17030	ENOG4105CGK	Exodeoxyribonuclease III
A6K25_17050	ENOG4105D60	lipoprotein releasing system transmembrane protein
A6K25_17060	ENOG4108JA2	transcriptioN-repair coupling factor
A6K25_17070	ENOG4108WBT	adenosyltransferase
A6K25_17075	ENOG4105C8P	)-transporter
A6K25_17080	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A6K25_17090	ENOG4108Z66	YbaK ebsC protein
A6K25_17100	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A6K25_17105	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A6K25_17110	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A6K25_17120	ENOG4105EXC	Acyl-transferase
A6K25_17125	ENOG4105JEU	Glycosyl transferase, family 2
A6K25_17160	ENOG4105C74	pyruvyl transferase
A6K25_17165	ENOG4107T8Q	Glycosyl transferase (Group 1
A6K25_17180	ENOG4108SHN	Glycosyl transferase, family 2
A6K25_17195	ENOG4105CG5	Glycosyl transferase (Group 1
A6K25_17205	ENOG4105BZU	Histidine kinase
A6K25_17230	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
A6K25_17235	ENOG4108QV3	biosynthesis protein
A6K25_17240	ENOG4105DAY	polysaccharide export protein
A6K25_17250	ENOG4105D3Q	Sugar transferase
A6K25_17260	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A6K25_17265	ENOG41082NX	50s ribosomal protein l35
A6K25_17270	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A6K25_17275	ENOG4105C22	threonyL-tRNA synthetase
A6K25_17280	ENOG410642E	Short chain dehydrogenase
A6K25_17310	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A6K25_17315	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A6K25_17320	ENOG4105HF0	Membrane
A6K25_17325	ENOG4105C5R	Aminotransferase
A6K25_17340	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A6K25_17345	ENOG4105C2W	permease
A6K25_17365	ENOG4105BZU	Histidine kinase
A6K25_17370	ENOG4105BZU	Histidine kinase
A6K25_17380	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A6K25_17385	ENOG4105C7N	Xanthine uracil vitamin C permease
A6K25_17400	ENOG4108R86	Transcriptional regulator
A6K25_17410	ENOG4105C7W	Xanthine dehydrogenase
A6K25_17430	ENOG4107QUY	Guanine deaminase
A6K25_17440	ENOG4105BZU	Histidine kinase
A6K25_17460	ENOG4105BZU	Histidine kinase
A6K25_17475	ENOG4105F1J	Homogentisate 1,2-dioxygenase
A6K25_17495	ENOG4107RBJ	symporter
A6K25_17500	ENOG4105KUZ	arsenate reductase
A6K25_17505	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A6K25_17520	ENOG4105K8R	UPF0145 protein
A6K25_17530	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
A6K25_17535	ENOG4105BZU	Histidine kinase
A6K25_17540	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A6K25_17545	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
A6K25_17550	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
A6K25_17555	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A6K25_17565	ENOG4105F8C	transglutaminase domain-containing protein
A6K25_17570	ENOG4105TMB	Formate nitrite transporter
A6K25_17575	ENOG4105D9P	serine threonine protein kinase
A6K25_17580	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
A6K25_17590	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
A6K25_17605	ENOG4105ETT	transcriptional Regulator, LysR family
A6K25_17615	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A6K25_17620	ENOG4108YY7	Invasion gene expression up-regulator SirB
A6K25_17625	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A6K25_17630	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A6K25_17635	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A6K25_17640	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A6K25_17645	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
A6K25_17650	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A6K25_17660	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A6K25_17665	ENOG4105BZU	Histidine kinase
A6K25_17675	ENOG4105DQ4	alcohol dehydrogenase
A6K25_17680	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A6K25_17685	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A6K25_17690	ENOG4105C3G	gtp-binding protein
A6K25_17695	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A6K25_17720	ENOG4105BZG	amino acid carrier protein
A6K25_17725	ENOG4107XWI	flavin reductase domain protein, FMN-binding
A6K25_17740	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
A6K25_17745	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A6K25_17750	ENOG4105C9A	Phoh family
A6K25_17755	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A6K25_17760	ENOG4108JU5	Magnesium and cobalt efflux protein
A6K25_17765	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A6K25_17770	ENOG4105C6K	Malic enzyme
A6K25_17775	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A6K25_17780	ENOG4108ZNX	Heat shock protein
A6K25_17805	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A6K25_17810	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A6K25_17815	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A6K25_17820	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A6K25_17830	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A6K25_17840	ENOG41085AF	Cytochrome
A6K25_17845	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A6K25_17850	ENOG4105CFG	Acts as a chaperone (By similarity)
A6K25_17855	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6K25_17875	ENOG4105CY2	Citrate transporter
A6K25_17880	ENOG4105DWV	Homoserine O-trans-acetylase
A6K25_17890	ENOG4105DTD	Dehydrogenase
A6K25_17895	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A6K25_17900	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A6K25_17905	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
A6K25_17910	ENOG4105FQ6	thiopurine methyltransferase
A6K25_17915	ENOG4106BRA	Membrane
A6K25_17930	ENOG4108UW5	maltose o-acetyltransferase
A6K25_17935	ENOG4105CV8	reductase
A6K25_17945	ENOG4105FE9	pseudouridine synthase
A6K25_17950	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A6K25_17955	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A6K25_17960	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A6K25_17965	ENOG4105DB7	PHP domain protein
A6K25_17970	ENOG4105CRQ	synthase (Component I)
A6K25_17980	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A6K25_17985	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A6K25_17990	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A6K25_17995	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A6K25_18000	ENOG4105K9H	YciI-like protein
A6K25_18015	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A6K25_18020	ENOG4105IFJ	Histidine kinase
A6K25_18025	ENOG4105DSF	transport protein
A6K25_18030	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
A6K25_18035	ENOG4105ECP	epimerase
A6K25_18040	ENOG4105CV6	ABC transporter, permease
A6K25_18045	ENOG4108I0Y	(ABC) transporter
A6K25_18050	ENOG4108UJV	acyl-CoA thioesterase i
A6K25_18065	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A6K25_18105	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A6K25_18125	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A6K25_18135	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A6K25_18140	ENOG4108JJ7	ABC transporter
A6K25_18155	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
A6K25_18165	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A6K25_18170	ENOG4105KJF	protein tyrosine phosphatase
A6K25_18180	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A6K25_18185	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A6K25_18190	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A6K25_18195	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A6K25_18200	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A6K25_18215	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A6K25_18220	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A6K25_18235	ENOG4105C5S	asparaginyl-tRNA synthetase
A6K25_18245	ENOG4105F1S	paraquat-inducible protein a
A6K25_18250	ENOG4105DY2	Paraquat-inducible protein b
A6K25_18260	ENOG4105BZU	Histidine kinase
A6K25_18280	ENOG4105CN8	Transcriptional regulator
A6K25_18285	ENOG4108XG4	DNA-binding transcriptional regulator
A6K25_18295	ENOG4105BZS	acriflavin resistance protein
A6K25_18300	ENOG4105W87	Cbs domain
A6K25_18315	ENOG4105HEI	LysR family (Transcriptional regulator
A6K25_18320	ENOG4105DS1	cytochrome b561
A6K25_18330	ENOG4108M8W	Monooxygenase
A6K25_18360	ENOG4105CXY	transporter
A6K25_18405	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A6K25_18415	ENOG4105BZU	Histidine kinase
A6K25_18440	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A6K25_18460	ENOG4105UFD	tol-pal system protein YbgF
A6K25_18465	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A6K25_18470	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
A6K25_18480	ENOG4105M8F	Biopolymer transport protein exbD tolR
A6K25_18485	ENOG4105E02	MotA TolQ exbB proton channel
A6K25_18490	ENOG4107YD3	Thioesterase
A6K25_18495	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A6K25_18500	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A6K25_18505	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A6K25_18510	ENOG4108TIT	dATP pyrophosphohydrolase
A6K25_18515	ENOG4105C9M	aspartyl-trna synthetase
A6K25_18530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_18540	ENOG4107WP9	Histidine kinase
A6K25_18550	ENOG4105BZU	Histidine kinase
A6K25_18560	ENOG4105BZU	Histidine kinase
A6K25_18570	ENOG4108ZJT	translation initiation factor, Sui1
A6K25_18575	ENOG4108VYJ	response regulator receiver protein
A6K25_18585	ENOG4108N3W	hemolysin secretion protein
A6K25_18595	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A6K25_18600	ENOG4105EN6	Membrane
A6K25_18615	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A6K25_18620	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A6K25_18625	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A6K25_18630	ENOG4105K5M	30s ribosomal protein S16
A6K25_18650	ENOG4105BZ1	(ABC) transporter
A6K25_18655	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A6K25_18665	ENOG4105DN9	Na H antiporter
A6K25_18695	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6K25_18700	ENOG4106KVJ	cytochrome C assembly protein
A6K25_18705	ENOG4108JU6	CBS domain protein
A6K25_18715	ENOG4108BY2	phosphohistidine phosphatase
A6K25_18720	ENOG4107QXK	peptidase
A6K25_18725	ENOG4105BZU	Histidine kinase
A6K25_18735	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A6K25_18740	ENOG4105CHU	acetyl-coa acetyltransferase
A6K25_18745	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A6K25_18765	ENOG4107QVM	von Willebrand factor, type A
A6K25_18790	ENOG4105BZU	Histidine kinase
A6K25_18795	ENOG4105CK7	Sodium proline symporter
A6K25_18800	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A6K25_18805	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A6K25_18810	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A6K25_18815	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A6K25_18845	ENOG4105CAQ	asparagine synthetase
A6K25_18855	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A6K25_18860	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A6K25_18880	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A6K25_18885	ENOG4107QJQ	Mate efflux family protein
A6K25_18900	ENOG4105DGN	Electron transport complex
A6K25_18905	ENOG4108R3D	Electron transport complex
A6K25_18915	ENOG4105D6A	Electron transport complex
A6K25_18920	ENOG4108UQQ	Electron transport complex
A6K25_18925	ENOG4105DZB	Electron transport complex
A6K25_18930	ENOG4105CSM	endonuclease III
A6K25_18955	ENOG4105DWV	Homoserine O-trans-acetylase
A6K25_18960	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A6K25_18975	ENOG4105BZU	Histidine kinase
A6K25_18985	ENOG4105VEQ	Cold shock protein
A6K25_18990	ENOG4108UYE	Lactoylglutathione lyase
A6K25_18995	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A6K25_19000	ENOG4105EIY	sodium-type flagellar protein motY
A6K25_19005	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A6K25_19010	ENOG4105D3R	alkyl hydroperoxide reductase
A6K25_19035	ENOG4105D05	Receptor
A6K25_19040	ENOG4105M2J	Glutaredoxin
A6K25_19045	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A6K25_19050	ENOG4105CYN	Serine protein kinase
A6K25_19060	ENOG4105ED1	spovr family
A6K25_19075	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A6K25_19080	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
A6K25_19090	ENOG4105BZU	Histidine kinase
A6K25_19095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_19110	ENOG4105C19	ABC transporter
A6K25_19130	ENOG4105D9M	gamma-glutamylcysteine synthetase
A6K25_19145	ENOG4108W1A	pseudouridine synthase
A6K25_19150	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A6K25_19155	ENOG4105CRK	lysyL-tRNA synthetase
A6K25_19160	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A6K25_19180	ENOG4108QDA	dioxygenase
A6K25_19195	ENOG4105BZU	Histidine kinase
A6K25_19200	ENOG4105C75	arginyL-tRNA synthetase
A6K25_19205	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A6K25_19210	ENOG4105HEI	LysR family (Transcriptional regulator
A6K25_19225	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
A6K25_19265	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A6K25_19275	ENOG410822N	TonB family
A6K25_19280	ENOG4109015	Biopolymer transport protein exbD tolR
A6K25_19330	ENOG4107RDJ	Sulfotransferase
A6K25_19335	ENOG4108KPZ	tonB-dependent Receptor
A6K25_19340	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
A6K25_19355	ENOG4107RDP	Dehydrogenase
A6K25_19360	ENOG4108XM1	transcriptional regulator AsnC family
A6K25_19365	ENOG4108RXX	maleylacetoacetate isomerase
A6K25_19380	ENOG4105MIR	Phenylalanine 4-monooxygenase
A6K25_19390	ENOG4105YYT	phage shock protein B
A6K25_19395	ENOG41087YS	Phage shock protein A
A6K25_19400	ENOG4105E51	psp operon transcriptional activator
A6K25_19405	ENOG4105DEF	Extracellular solute-binding protein, family 5
A6K25_19410	ENOG4108I5W	peptide transport system, permease protein
A6K25_19415	ENOG4108EU3	peptide transport system, permease
A6K25_19420	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
A6K25_19425	ENOG4108JQ2	peptide transport system atp-binding protein
A6K25_19430	ENOG4105D9Q	decarboxylase (Beta subunit)
A6K25_19435	ENOG4107QSA	Oxaloacetate decarboxylase
A6K25_19445	ENOG4105NAU	thioesterase Superfamily protein
A6K25_19465	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
A6K25_19470	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A6K25_19485	ENOG4105C9K	Endothelin-converting enzyme 1
A6K25_19490	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
A6K25_19500	ENOG4105CHH	sulfate transporter
A6K25_19505	ENOG4107B2H	carbonic anhydrase
A6K25_19510	ENOG4105C5Q	Transcriptional regulator
A6K25_19515	ENOG4105DZ2	Transcriptional regulator
A6K25_19525	ENOG4105C3R	Methionine synthase
A6K25_19530	ENOG4105C3R	Methionine synthase
A6K25_19535	ENOG4105CVG	Homoserine O-transsuccinylase
A6K25_19545	ENOG4105YFD	chemotaxis, protein
A6K25_19555	ENOG4107QJE	Chromosome Partitioning Protein
A6K25_19565	ENOG4105CBS	Chea signal transduction histidine kinase
A6K25_19570	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
A6K25_19575	ENOG4108VYJ	response regulator receiver protein
A6K25_19580	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A6K25_19590	ENOG4105FZW	flagellar biosynthesis regulator FlhF
A6K25_19595	ENOG4105D7B	Flagellar biosynthesis protein flha
A6K25_19600	ENOG4105D00	flagellar biosynthetic protein flhB
A6K25_19605	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A6K25_19610	ENOG4105VS8	Flagellar biosynthetic protein fliq
A6K25_19615	ENOG4105CN7	Flagellar biosynthetic protein FliP
A6K25_19620	ENOG4105VTB	flagellar biosynthesis protein fliO
A6K25_19625	ENOG4105DD5	Flagellar motor switch protein
A6K25_19630	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A6K25_19650	ENOG4108JIR	Flagellum-specific ATP synthase
A6K25_19660	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A6K25_19665	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A6K25_19675	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_19680	ENOG4105BZU	Histidine kinase
A6K25_19685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A6K25_19695	ENOG4105C5E	polysaccharide biosynthesis protein
A6K25_19700	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A6K25_19705	ENOG4105F0R	Cytidylyltransferase
A6K25_19735	ENOG4105CHR	reductase
A6K25_19775	ENOG4105D2T	synthase
A6K25_19780	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A6K25_19785	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
A6K25_19810	ENOG4105MQ3	flagellar protein FliS
A6K25_19820	ENOG41063QE	flagellar protein FlaG
A6K25_19825	ENOG4105I03	Flagellin
A6K25_19830	ENOG4105I03	Flagellin
A6K25_19835	ENOG4105I03	Flagellin
A6K25_19850	ENOG4105E1Q	flagellar hook-associated protein
A6K25_19855	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
A6K25_19860	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A6K25_19865	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
A6K25_19870	ENOG4105CGA	flagellar basal-body rod protein FlgG
A6K25_19875	ENOG4108KPB	Flagellar basal-body rod protein FlgF
A6K25_19880	ENOG4105BZE	flagellar hook protein, FlgE
A6K25_19885	ENOG4105W00	Flagellar hook capping protein
A6K25_19890	ENOG4108ZC9	flagellar basal-body rod protein flgc
A6K25_19895	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
A6K25_19900	ENOG4105BZU	Histidine kinase
A6K25_19905	ENOG4107R88	Chemotaxis protein (CheV)
A6K25_19945	ENOG4105WH1	Two component transcriptional regulator luxr family
A6K25_19955	ENOG4108JJA	ABC, transporter
A6K25_19960	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
A6K25_19970	ENOG4105IYK	transposase
A6K25_19975	ENOG4105DQ6	Transposase
A6K25_19990	ENOG4108DG9	Smr protein MutS2
A6K25_19995	ENOG4108ETH	Formylglycinamide ribotide synthetase
A6K25_20000	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
A6K25_20005	ENOG4108Z6B	deaminase
A6K25_20020	ENOG4105BZU	Histidine kinase
A6K25_20025	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A6K25_20030	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A6K25_20035	ENOG4105C0B	DNA polymerase III (alpha subunit)
A6K25_20040	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A6K25_20045	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6K25_20050	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A6K25_20055	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
A6K25_20070	ENOG4105DZP	Membrane-associated zinc metalloprotease
A6K25_20075	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
A6K25_20080	ENOG4105KNE	Phosphatidate cytidylyltransferase
A6K25_20085	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A6K25_20090	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A6K25_20095	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A6K25_20100	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A6K25_20105	ENOG4105CE9	30S ribosomal protein S2
A6K25_20110	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A6K25_20115	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A6K25_20120	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A6K25_20125	ENOG4105QDK	Flavodoxin
A6K25_20130	ENOG4105DR9	pseudouridine synthase
A6K25_20170	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A6K25_20195	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
A6K25_20200	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
A6K25_20205	ENOG4105BZU	Histidine kinase
A6K25_20210	ENOG4105EWT	decarboxylase family
A6K25_20225	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A6K25_20230	ENOG4105KQC	Competence protein
A6K25_20235	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A6K25_20245	ENOG4108RYC	glycosyltransferase
A6K25_20250	ENOG4105ESV	Glycosyl transferase, family 4
A6K25_20260	ENOG4107V1M	polysaccharide export protein
A6K25_20265	ENOG41090SZ	ABC-2 type transporter
A6K25_20280	ENOG4105DUX	Transporter
A6K25_20290	ENOG4105CMR	udp-glucose 4-epimerase
A6K25_20295	ENOG410903C	(LipO)protein