locus-tag	class	description
H3L97_00015	COG0592	DNA-directed DNA polymerase activity
H3L97_00020	COG1116	anion transmembrane transporter activity
H3L97_00030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H3L97_00040	COG1335	isochorismatase
H3L97_00045	COG1522	sequence-specific DNA binding
H3L97_00065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H3L97_00070	COG2999	glutathione oxidoreductase activity
H3L97_00130	COG2841	Protein conserved in bacteria
H3L97_00155	COG0791	NLP P60 protein
H3L97_00195	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H3L97_00305	COG2824	Alkylphosphonate utilization operon protein PhnA
H3L97_00330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H3L97_00340	COG4650	regulator
H3L97_00345	COG1477	protein flavinylation
H3L97_00365	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H3L97_00380	COG3179	chitinase
H3L97_00390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3L97_00395	COG0814	amino acid
H3L97_00405	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H3L97_00435	COG0561	phosphatase activity
H3L97_00465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H3L97_00475	COG0297	glycogen (starch) synthase activity
H3L97_00480	COG0058	SHG alpha-glucan phosphorylase activity
H3L97_00495	COG1268	BioY protein
H3L97_00550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3L97_00560	COG0463	Glycosyl transferase, family 2
H3L97_00585	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
H3L97_00595	COG0512	Glutamine amidotransferase of anthranilate synthase
H3L97_00600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H3L97_00625	COG0210	DNA helicase
H3L97_00685	COG0582	viral genome integration into host DNA
H3L97_00695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H3L97_00710	COG0288	reversible hydration of carbon dioxide
H3L97_00715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H3L97_00720	COG0799	negative regulation of ribosome biogenesis
H3L97_00730	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H3L97_00740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H3L97_00745	COG0295	cytidine deaminase activity
H3L97_00815	COG0372	Belongs to the citrate synthase family
H3L97_00830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H3L97_00840	COG2828	Protein conserved in bacteria
H3L97_00850	COG3842	ATPase activity
H3L97_00855	COG1176	ABC-type spermidine putrescine transport system, permease component I
H3L97_00860	COG1177	transmembrane transport
H3L97_00900	COG0783	Belongs to the Dps family
H3L97_00905	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H3L97_00910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H3L97_00920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H3L97_00980	COG1183	phosphatidylcholine synthase activity
H3L97_00985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H3L97_01075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H3L97_01080	COG0456	acetyltransferase
H3L97_01175	COG0633	Ferredoxin
H3L97_01230	COG4208	sulfate ABC transporter
H3L97_01240	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H3L97_01275	COG1902	pentaerythritol trinitrate reductase activity
H3L97_01290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H3L97_01305	COG1741	Belongs to the pirin family
H3L97_01395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H3L97_01400	COG0583	DNA-binding transcription factor activity
H3L97_01415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H3L97_01430	COG2984	ABC transporter substrate binding protein
H3L97_01450	COG2217	Heavy metal translocating P-type atpase
H3L97_01455	COG4615	Cyclic peptide transporter
H3L97_01485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3L97_01500	COG2755	lipolytic protein G-D-S-L family
H3L97_01540	COG1643	Atp-dependent helicase
H3L97_01570	COG3045	CreA protein
H3L97_01600	COG0805	protein transport
H3L97_01615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H3L97_01615	COG0616	signal peptide processing
H3L97_01625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H3L97_01640	COG0514	ATP-dependent DNA helicase (RecQ)
H3L97_01670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H3L97_01675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H3L97_01680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3L97_01705	COG0803	Belongs to the bacterial solute-binding protein 9 family
H3L97_01745	COG0586	Pfam SNARE associated Golgi protein
H3L97_01775	COG1399	metal-binding, possibly nucleic acid-binding protein
H3L97_01805	COG1696	Membrane protein involved in D-alanine export
H3L97_01865	COG1408	metallophosphoesterase
H3L97_01870	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H3L97_01880	COG3266	domain, Protein
H3L97_01885	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
H3L97_01890	COG0523	cobalamin synthesis protein
H3L97_01925	COG0513	Belongs to the DEAD box helicase family
H3L97_01945	COG4589	Belongs to the CDS family
H3L97_01995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H3L97_02015	COG0583	DNA-binding transcription factor activity
H3L97_02065	COG2207	Transcriptional regulator
H3L97_02070	COG0300	oxidoreductase activity
H3L97_02080	COG0628	permease
H3L97_02120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H3L97_02135	COG2911	Protein conserved in bacteria
H3L97_02145	COG0729	surface antigen
H3L97_02230	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H3L97_02290	COG2070	2-Nitropropane dioxygenase
H3L97_02305	COG0247	lactate metabolic process
H3L97_02325	COG1139	Iron-sulfur cluster binding protein
H3L97_02335	COG1203	CRISPR-associated helicase, Cas3
H3L97_02385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H3L97_02415	COG1881	PFAM PEBP family protein
H3L97_02420	COG1739	Uncharacterized protein family UPF0029
H3L97_02425	COG3738	Protein conserved in bacteria
H3L97_02465	COG2086	electron transfer activity
H3L97_02470	COG0859	PFAM glycosyl transferase family 9
H3L97_02485	COG1132	(ABC) transporter
H3L97_02505	COG0393	Putative heavy-metal-binding
H3L97_02510	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H3L97_02545	COG1690	Belongs to the RtcB family
H3L97_02555	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H3L97_02580	COG2226	methyltransferase
H3L97_02590	COG2707	UPF0756 membrane protein
H3L97_02595	COG0142	geranyltranstransferase activity
H3L97_02600	COG2884	Cell division ATP-binding protein ftsE
H3L97_02615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H3L97_02615	COG0758	DNA mediated transformation
H3L97_02670	COG0737	Belongs to the 5'-nucleotidase family
H3L97_02675	COG0742	ribosomal rna small subunit methyltransferase
H3L97_02680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H3L97_02875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H3L97_02965	COG0201	protein transport
H3L97_02975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H3L97_03035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H3L97_03075	COG3842	ATPase activity
H3L97_03110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H3L97_03135	COG3118	belongs to the thioredoxin family
H3L97_03140	COG0494	nUDIX hydrolase
H3L97_03145	COG1737	Transcriptional regulator
H3L97_03150	COG1376	ErfK ybiS ycfS ynhG family protein
H3L97_03170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H3L97_03180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H3L97_03185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H3L97_03195	COG1215	transferase activity, transferring glycosyl groups
H3L97_03195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H3L97_03205	COG1335	isochorismatase
H3L97_03230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H3L97_03245	COG0800	Aldolase
H3L97_03285	COG1733	regulation of RNA biosynthetic process
H3L97_03295	COG2259	Doxx family
H3L97_03305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H3L97_03330	COG0129	dihydroxy-acid dehydratase activity
H3L97_03365	COG0196	riboflavin kinase activity
H3L97_03370	COG0765	amino acid transport
H3L97_03385	COG0463	Glycosyl transferase, family 2
H3L97_03390	COG2246	polysaccharide biosynthetic process
H3L97_03405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H3L97_03435	COG0583	DNA-binding transcription factor activity
H3L97_03465	COG3263	regulation of cellular component size
H3L97_03480	COG0308	aminopeptidase N
H3L97_03500	COG0860	N-Acetylmuramoyl-L-alanine amidase
H3L97_03515	COG1999	signal sequence binding
H3L97_03530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H3L97_03565	COG0583	DNA-binding transcription factor activity
H3L97_03615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H3L97_03680	COG2252	PERMEase
H3L97_03775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H3L97_03845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H3L97_03880	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H3L97_03890	COG2852	Protein conserved in bacteria
H3L97_03925	COG0839	Belongs to the complex I subunit 6 family
H3L97_04010	COG1115	amino acid carrier protein
H3L97_04015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H3L97_04025	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H3L97_04045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H3L97_04075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H3L97_04085	COG1333	cytochrome c biogenesis protein
H3L97_04100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H3L97_04110	COG2878	Part of a membrane complex involved in electron transport
H3L97_04155	COG4221	oxidoreductase activity
H3L97_04160	COG3909	cytochrome
H3L97_04170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H3L97_04190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H3L97_04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H3L97_04230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H3L97_04270	COG2951	lytic endotransglycosylase activity
H3L97_04280	COG2056	Na+-H+ antiporter family
H3L97_04285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H3L97_04290	COG0612	Peptidase, M16
H3L97_04300	COG0429	hydrolase of the alpha beta-hydrolase fold
H3L97_04390	COG1278	Cold shock
H3L97_04400	COG0542	response to heat
H3L97_04410	COG4774	siderophore transport
H3L97_04415	COG1120	ATPase activity
H3L97_04425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3L97_04475	COG2847	Copper chaperone PCu(A)C
H3L97_04480	COG0009	L-threonylcarbamoyladenylate synthase
H3L97_04600	COG2249	NAD(P)H dehydrogenase (quinone) activity
H3L97_04610	COG1902	pentaerythritol trinitrate reductase activity
H3L97_04615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H3L97_04620	COG1902	pentaerythritol trinitrate reductase activity
H3L97_04625	COG0778	Nitroreductase
H3L97_04640	COG1064	alcohol dehydrogenase
H3L97_04720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H3L97_04765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H3L97_04830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H3L97_04880	COG2267	carboxylic ester hydrolase activity
H3L97_04885	COG2453	phosphatase
H3L97_04885	COG0671	phosphoesterase, PA-phosphatase related
H3L97_04895	COG3264	Mechanosensitive ion channel
H3L97_04895	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H3L97_04900	COG0494	nUDIX hydrolase
H3L97_04905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H3L97_04990	COG0739	heme binding
H3L97_04990	COG0741	lytic transglycosylase activity
H3L97_04990	COG1196	nuclear chromosome segregation
H3L97_04995	COG1522	sequence-specific DNA binding
H3L97_05000	COG0697	spore germination
H3L97_05015	COG0351	phosphomethylpyrimidine kinase
H3L97_05020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H3L97_05110	COG0542	response to heat
H3L97_05130	COG2315	Protein conserved in bacteria
H3L97_05160	COG0723	plastoquinol--plastocyanin reductase activity
H3L97_05165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H3L97_05170	COG2857	Cytochrome c1
H3L97_05250	COG0671	phosphoesterase, PA-phosphatase related
H3L97_05260	COG0494	nUDIX hydrolase
H3L97_05270	COG0739	heme binding
H3L97_05290	COG0613	PHP domain protein
H3L97_05300	COG0024	Methionine aminopeptidase
H3L97_05325	COG2975	iron-sulfur cluster assembly
H3L97_05340	COG1530	ribonuclease E activity
H3L97_05350	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
H3L97_05355	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
H3L97_05390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H3L97_05395	COG0601	transmembrane transport
H3L97_05415	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H3L97_05435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H3L97_05445	COG0191	fructose-bisphosphate aldolase activity
H3L97_05480	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H3L97_05485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H3L97_05495	COG0339	signal peptide processing
H3L97_05520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3L97_05525	COG0697	spore germination
H3L97_05530	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
H3L97_05540	COG0477	Major facilitator Superfamily
H3L97_05575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H3L97_05580	COG0259	pyridoxamine-phosphate oxidase activity
H3L97_05630	COG1522	sequence-specific DNA binding
H3L97_05635	COG2962	Rard protein
H3L97_05645	COG3041	Addiction module toxin RelE StbE family
H3L97_05705	COG4535	Mg2 and Co2 transporter CorC
H3L97_05715	COG3040	lipid binding
H3L97_05770	COG2814	Major facilitator Superfamily
H3L97_05780	COG0765	amino acid transport
H3L97_05785	COG1126	abc transporter atp-binding protein
H3L97_05790	COG0488	(ABC) transporter
H3L97_05805	COG2340	Cysteine-rich secretory protein family
H3L97_05825	COG0248	Ppx GppA phosphatase
H3L97_05835	COG2354	Protein conserved in bacteria
H3L97_05845	COG0492	ferredoxin-NADP+ reductase activity
H3L97_05855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3L97_05900	COG1012	belongs to the aldehyde dehydrogenase family
H3L97_05905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H3L97_05925	COG0501	Belongs to the peptidase M48B family
H3L97_05930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H3L97_05950	COG0730	response to heat
H3L97_05955	COG0287	Prephenate dehydrogenase
H3L97_06005	COG4989	oxidoreductase activity
H3L97_06025	COG2201	protein-glutamate methylesterase activity
H3L97_06040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H3L97_06040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H3L97_06070	COG0277	FAD linked oxidase domain protein
H3L97_06095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H3L97_06110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H3L97_06125	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H3L97_06145	COG0626	cystathionine gamma-synthase activity
H3L97_06160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H3L97_06180	COG0142	geranyltranstransferase activity
H3L97_06185	COG1722	exodeoxyribonuclease VII activity
H3L97_06200	COG0121	glutamine amidotransferase
H3L97_06220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3L97_06225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H3L97_06235	COG1121	(ABC) transporter
H3L97_06245	COG1115	amino acid carrier protein
H3L97_06250	COG0786	glutamate:sodium symporter activity
H3L97_06255	COG0012	GTP binding
H3L97_06290	COG2195	Cleaves the N-terminal amino acid of tripeptides
H3L97_06300	COG0745	RESPONSE REGULATOR receiver
H3L97_06305	COG4452	Inner membrane protein CreD
H3L97_06310	COG1187	pseudouridine synthase activity
H3L97_06320	COG3700	Belongs to the class B bacterial acid phosphatase family
H3L97_06325	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H3L97_06355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H3L97_06360	COG1042	CoA-binding domain protein
H3L97_06360	COG0045	succinate-CoA ligase (ADP-forming) activity
H3L97_06360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H3L97_06385	COG0439	Biotin carboxylase
H3L97_06400	COG0511	ligase activity, forming carbon-carbon bonds
H3L97_06420	COG3831	ATPase activity
H3L97_06445	COG0714	Associated with various cellular activities
H3L97_06460	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H3L97_06480	COG1448	Aminotransferase
H3L97_06500	COG1252	NADH dehydrogenase
H3L97_06505	COG1914	H( )-stimulated, divalent metal cation uptake system
H3L97_06520	COG4115	mRNA cleavage
H3L97_06525	COG2161	toxin-antitoxin pair type II binding
H3L97_06540	COG1984	allophanate hydrolase subunit 2
H3L97_06545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H3L97_06565	COG0560	Phosphoserine phosphatase
H3L97_06585	COG3278	Belongs to the heme-copper respiratory oxidase family
H3L97_06600	COG2010	Cytochrome c
H3L97_06605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H3L97_06610	COG0463	Glycosyl transferase, family 2
H3L97_06625	COG0802	atpase or kinase
H3L97_06635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H3L97_06645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H3L97_06660	COG1561	YicC-like family, N-terminal region
H3L97_06670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H3L97_06690	COG0633	Ferredoxin
H3L97_06705	COG0348	domain, Protein
H3L97_06735	COG0356	it plays a direct role in the translocation of protons across the membrane
H3L97_06780	COG0084	hydrolase, TatD family'
H3L97_06795	COG1546	Belongs to the CinA family
H3L97_06805	COG0840	transmembrane signaling receptor activity
H3L97_06830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H3L97_06840	COG2851	Citrate transporter
H3L97_06885	COG0756	dUTP diphosphatase activity
H3L97_06925	COG0163	prenyltransferase activity
H3L97_06930	COG0489	protein tyrosine kinase activity
H3L97_07020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3L97_07040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H3L97_07045	COG0069	glutamate synthase activity
H3L97_07050	COG1620	l-lactate permease
H3L97_07070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H3L97_07070	COG3453	Protein conserved in bacteria
H3L97_07085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H3L97_07095	COG2832	Protein of unknown function (DUF454)
H3L97_07100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H3L97_07105	COG5007	Belongs to the BolA IbaG family
H3L97_07110	COG2350	Protein conserved in bacteria
H3L97_07135	COG1194	a g-specific adenine glycosylase
H3L97_07150	COG3219	Protein conserved in bacteria
H3L97_07170	COG2259	Doxx family
H3L97_07175	COG2204	response regulator
H3L97_07180	COG5000	phosphorelay sensor kinase activity
H3L97_07190	COG1196	nuclear chromosome segregation
H3L97_07220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H3L97_07245	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
H3L97_07280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H3L97_07290	COG1686	Belongs to the peptidase S11 family
H3L97_07295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H3L97_07300	COG0436	Aminotransferase
H3L97_07330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H3L97_07340	COG0076	glutamate decarboxylase activity
H3L97_07355	COG0488	(ABC) transporter
H3L97_07375	COG3161	chorismate lyase activity
H3L97_07400	COG2095	MarC family integral membrane protein
H3L97_07415	COG2201	protein-glutamate methylesterase activity
H3L97_07465	COG1077	Cell shape determining protein MreB Mrl
H3L97_07470	COG1792	Involved in formation and maintenance of cell shape
H3L97_07480	COG0768	penicillin binding
H3L97_07485	COG0772	Belongs to the SEDS family
H3L97_07495	COG0714	Associated with various cellular activities
H3L97_07515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H3L97_07520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H3L97_07540	COG2866	Carboxypeptidase
H3L97_07605	COG0285	dihydrofolate synthase activity
H3L97_07615	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H3L97_07625	COG0859	PFAM glycosyl transferase family 9
H3L97_07635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H3L97_07670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3L97_07675	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H3L97_07680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H3L97_07685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H3L97_07705	COG0471	metal ion transport
H3L97_07710	COG0747	negative chemotaxis
H3L97_07715	COG0601	transmembrane transport
H3L97_07720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H3L97_07725	COG0444	Belongs to the ABC transporter superfamily
H3L97_07735	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H3L97_07740	COG0697	spore germination
H3L97_07780	COG0488	(ABC) transporter
H3L97_07815	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H3L97_07820	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
H3L97_07825	COG1652	LysM domain
H3L97_07850	COG0277	FAD linked oxidase domain protein
H3L97_07860	COG0778	Nitroreductase
H3L97_07905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H3L97_07910	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H3L97_07910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H3L97_07915	COG0210	DNA helicase
H3L97_07920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H3L97_07920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H3L97_07940	COG1686	Belongs to the peptidase S11 family
H3L97_07945	COG0477	Major facilitator Superfamily
H3L97_07975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H3L97_08015	COG0579	oxidoreductase
H3L97_08030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H3L97_08050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H3L97_08060	COG2814	Major facilitator Superfamily
H3L97_08075	COG1466	dna polymerase III delta subunit
H3L97_08085	COG0583	DNA-binding transcription factor activity
H3L97_08100	COG4942	peptidase
H3L97_08105	COG3030	protein affecting phage T7 exclusion by the F plasmid
H3L97_08110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H3L97_08135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H3L97_08150	COG1049	propionate catabolic process, 2-methylcitrate cycle
H3L97_08165	COG3781	membrane
H3L97_08175	COG1760	l-serine dehydratase
H3L97_08220	COG0268	Binds directly to 16S ribosomal RNA
H3L97_08230	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H3L97_08235	COG0714	Associated with various cellular activities
H3L97_08240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H3L97_08250	COG0508	dehydrogenase complex catalyzes the overall conversion of
H3L97_08270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H3L97_08275	COG0431	NADPH-dependent FMN reductase
H3L97_08295	COG1970	mechanosensitive ion channel activity
H3L97_08305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H3L97_08310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H3L97_08315	COG1074	ATP-dependent DNA helicase activity
H3L97_08330	COG1966	Carbon starvation protein
H3L97_08355	COG3878	Protein conserved in bacteria
H3L97_08360	COG0793	Belongs to the peptidase S41A family
H3L97_08370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H3L97_08375	COG1854	S-ribosylhomocysteine lyase activity
H3L97_08385	COG1476	TRANSCRIPTIONal
H3L97_08405	COG2186	Transcriptional regulator
H3L97_08410	COG1028	Short-chain dehydrogenase reductase Sdr
H3L97_08420	COG4948	Mandelate Racemase Muconate Lactonizing
H3L97_08430	COG1028	Short-chain dehydrogenase reductase Sdr
H3L97_08440	COG1129	ABC transporter
H3L97_08460	COG0484	heat shock protein binding
H3L97_08570	COG2364	Membrane
H3L97_08600	COG3307	-O-antigen
H3L97_08605	COG0745	RESPONSE REGULATOR receiver
H3L97_08610	COG2205	protein histidine kinase activity
H3L97_08630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H3L97_08665	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H3L97_08665	COG2813	Specifically methylates the guanine in position
H3L97_08670	COG1187	pseudouridine synthase activity
H3L97_08680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H3L97_08715	COG1045	serine acetyltransferase
H3L97_08735	COG1448	Aminotransferase
H3L97_08740	COG0084	hydrolase, TatD family'
H3L97_08745	COG0316	Belongs to the HesB IscA family
H3L97_08750	COG0822	iron-sulfur transferase activity
H3L97_08785	COG0708	Exodeoxyribonuclease III
H3L97_08805	COG3977	Valine--pyruvate aminotransferase
H3L97_08810	COG1199	ATP-dependent helicase activity
H3L97_08815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H3L97_08870	COG3008	intermembrane lipid transfer
H3L97_08870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H3L97_08875	COG2995	paraquat-inducible protein a
H3L97_08880	COG0586	Pfam SNARE associated Golgi protein
H3L97_08895	COG0440	acetolactate synthase activity
H3L97_08900	COG0028	Belongs to the TPP enzyme family
H3L97_08910	COG4969	Belongs to the N-Me-Phe pilin family
H3L97_08925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H3L97_08935	COG1702	phosphate starvation-inducible protein PhoH
H3L97_08965	COG0105	UTP biosynthetic process
H3L97_09000	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H3L97_09010	COG0442	prolyl-tRNA aminoacylation
H3L97_09015	COG4774	siderophore transport
H3L97_09020	COG4178	(ABC) transporter
H3L97_09060	COG0252	asparaginase activity
H3L97_09070	COG0312	modulator of DNA gyrase
H3L97_09075	COG0857	belongs to the CobB CobQ family
H3L97_09075	COG0280	phosphate acetyltransferase
H3L97_09085	COG0366	Alpha amylase catalytic
H3L97_09090	COG0494	nUDIX hydrolase
H3L97_09105	COG0513	Belongs to the DEAD box helicase family
H3L97_09135	COG0625	glutathione transferase activity
H3L97_09140	COG2969	positive regulation of protein catabolic process
H3L97_09175	COG1253	flavin adenine dinucleotide binding
H3L97_09185	COG2431	L-lysine efflux transmembrane transporter activity
H3L97_09190	COG0187	DNA topoisomerase II activity
H3L97_09245	COG2310	stress, protein
H3L97_09260	COG1346	cytolysis
H3L97_09270	COG0477	Major facilitator Superfamily
H3L97_09275	COG1388	LysM domain
H3L97_09275	COG4942	peptidase
H3L97_09280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H3L97_09290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H3L97_09310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H3L97_09315	COG0318	PFAM AMP-dependent synthetase and ligase
H3L97_09320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H3L97_09340	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H3L97_09345	COG1028	Short-chain dehydrogenase reductase Sdr
H3L97_09355	COG2239	Acts as a magnesium transporter
H3L97_09375	COG0737	Belongs to the 5'-nucleotidase family
H3L97_09390	COG1289	transmembrane transporter activity
H3L97_09400	COG0508	dehydrogenase complex catalyzes the overall conversion of
H3L97_09415	COG1307	EDD domain protein, DegV family
H3L97_09420	COG0569	domain protein
H3L97_09445	COG1473	amidohydrolase
H3L97_09475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H3L97_09510	COG1053	succinate dehydrogenase
H3L97_09515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H3L97_09520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H3L97_09535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H3L97_09565	COG1388	LysM domain
H3L97_09565	COG0741	lytic transglycosylase activity
H3L97_09660	COG1560	Kdo2-lipid A biosynthetic process
H3L97_09680	COG3150	esterase
H3L97_09685	COG1476	TRANSCRIPTIONal
H3L97_09720	COG2852	Protein conserved in bacteria
H3L97_09735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H3L97_09740	COG2268	Band 7 protein
H3L97_09800	COG1086	Polysaccharide biosynthesis protein
H3L97_09830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H3L97_09840	COG0519	Catalyzes the synthesis of GMP from XMP
H3L97_09845	COG0443	Heat shock 70 kDa protein
H3L97_09860	COG0497	DNA recombination
H3L97_09870	COG0347	Belongs to the P(II) protein family
H3L97_09880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H3L97_09890	COG4211	Belongs to the binding-protein-dependent transport system permease family
H3L97_09895	COG1129	ABC transporter
H3L97_09905	COG1085	galactose-1-phosphate uridylyltransferase
H3L97_09915	COG1192	Involved in chromosome partitioning
H3L97_09925	COG1083	cytidylyl-transferase
H3L97_09935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H3L97_09940	COG1162	GTPase activity
H3L97_09950	COG2089	acid synthase
H3L97_09960	COG2244	polysaccharide biosynthetic process
H3L97_09980	COG1216	Glycosyl transferase, family 2
H3L97_09980	COG1442	glycosyl transferase family 8
H3L97_09990	COG1216	Glycosyl transferase, family 2
H3L97_09995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H3L97_10005	COG2201	protein-glutamate methylesterase activity
H3L97_10020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H3L97_10045	COG1137	ATPase activity
H3L97_10050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H3L97_10060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H3L97_10065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H3L97_10065	COG0517	IMP dehydrogenase activity
H3L97_10085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H3L97_10090	COG0471	metal ion transport
H3L97_10095	COG2885	chlorophyll binding
H3L97_10100	COG2814	Major facilitator Superfamily
H3L97_10110	COG1619	proteins homologs of microcin C7 resistance protein MccF
H3L97_10115	COG3306	glycosyltransferase involved in LPS biosynthesis
H3L97_10130	COG2211	Major facilitator Superfamily
H3L97_10145	COG0544	peptidyl-prolyl cis-trans isomerase activity
H3L97_10160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H3L97_10190	COG4604	ABC transporter, ATP-binding protein
H3L97_10195	COG1846	Transcriptional regulator
H3L97_10200	COG4605	iron ion homeostasis
H3L97_10210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H3L97_10220	COG4682	membrane
H3L97_10225	COG4607	ABC-type enterochelin transport system periplasmic component
H3L97_10255	COG0251	oxidation-reduction process
H3L97_10290	COG3133	Outer membrane lipoprotein
H3L97_10305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H3L97_10365	COG0733	neurotransmitter:sodium symporter activity
H3L97_10375	COG0733	neurotransmitter:sodium symporter activity
H3L97_10445	COG0557	exoribonuclease II activity
H3L97_10460	COG2831	hemolysin activation secretion protein
H3L97_10465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H3L97_10475	COG1464	Belongs to the NlpA lipoprotein family
H3L97_10510	COG2011	ABC-type metal ion transport system permease component
H3L97_10515	COG3077	Addiction module antitoxin, RelB DinJ family
H3L97_10520	COG1794	racemase activity, acting on amino acids and derivatives
H3L97_10530	COG0483	inositol monophosphate 1-phosphatase activity
H3L97_10535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H3L97_10550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H3L97_10570	COG2194	sulfuric ester hydrolase activity
H3L97_10590	COG2610	gluconate transmembrane transporter activity
H3L97_10595	COG1929	Belongs to the glycerate kinase type-1 family
H3L97_10630	COG1538	Outer membrane efflux protein
H3L97_10635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H3L97_10650	COG1530	ribonuclease E activity
H3L97_10745	COG1215	transferase activity, transferring glycosyl groups
H3L97_10765	COG0602	queuosine metabolic process
H3L97_10770	COG0720	synthase
H3L97_10840	COG0582	viral genome integration into host DNA
H3L97_10895	COG0745	RESPONSE REGULATOR receiver
H3L97_10900	COG0642	Histidine kinase
H3L97_10920	COG2954	triphosphatase activity
H3L97_10935	COG0531	amino acid
H3L97_10955	COG0583	DNA-binding transcription factor activity
H3L97_10960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H3L97_10970	COG3468	outer membrane autotransporter barrel domain protein
H3L97_10970	COG3266	domain, Protein
H3L97_10995	COG0312	modulator of DNA gyrase
H3L97_11000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H3L97_11020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H3L97_11050	COG0506	proline dehydrogenase activity
H3L97_11050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H3L97_11050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H3L97_11055	COG3104	oligopeptide transport
H3L97_11075	COG0237	dephospho-CoA kinase activity
H3L97_11080	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H3L97_11120	COG0469	pyruvate kinase activity
H3L97_11130	COG1505	serine-type exopeptidase activity
H3L97_11145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H3L97_11285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H3L97_11290	COG1126	abc transporter atp-binding protein
H3L97_11295	COG0765	amino acid transport
H3L97_11300	COG0765	amino acid transport
H3L97_11305	COG1765	OsmC-like protein
H3L97_11315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H3L97_11325	COG0037	tRNA processing
H3L97_11350	COG0307	riboflavin synthase, alpha
H3L97_11370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H3L97_11415	COG2833	Protein of unknown function (DUF455)
H3L97_11420	COG3945	hemerythrin HHE cation binding domain
H3L97_11430	COG0589	response to stress
H3L97_11435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H3L97_11440	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H3L97_11470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H3L97_11505	COG0195	Participates in both transcription termination and antitermination
H3L97_11520	COG2217	Heavy metal translocating P-type atpase
H3L97_11535	COG3265	gluconokinase activity
H3L97_11540	COG2610	gluconate transmembrane transporter activity
H3L97_11545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H3L97_11550	COG3038	cytochrome b561
H3L97_11575	COG2261	transglycosylase associated protein
H3L97_11580	COG2321	neutral zinc metallopeptidase
H3L97_11590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H3L97_11630	COG1028	Short-chain dehydrogenase reductase Sdr
H3L97_11640	COG0542	response to heat
H3L97_11660	COG1216	Glycosyl transferase, family 2
H3L97_11660	COG1442	glycosyl transferase family 8
H3L97_11685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H3L97_11705	COG1127	ABC transporter
H3L97_11710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H3L97_11715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H3L97_11740	COG0824	Thioesterase
H3L97_11760	COG1519	Transferase
H3L97_11795	COG1214	PFAM Peptidase M22, glycoprotease