locus-tag class description Ami3637_00025 ENOG4105FDF Could be involved in DNA repair (By similarity) Ami3637_00035 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) Ami3637_00065 ENOG4108JUB Transcriptional regulator Ami3637_00080 ENOG4105CPN adenine deaminase Ami3637_00085 ENOG4105CPN adenine deaminase Ami3637_00090 ENOG410847I Transcriptional regulator, BadM Rrf2 family Ami3637_00110 ENOG4105C1J atp-dependent rna helicase Ami3637_00115 ENOG4105KVH Transcriptional regulator Ami3637_00160 ENOG4107R7I amino acid Ami3637_00175 ENOG4105CEB Aspartate aminotransferase Ami3637_00185 ENOG4106P55 Transcriptional regulator Ami3637_00200 ENOG4105CUB amino acid Ami3637_00210 ENOG4105W1Y Transcriptional regulator Ami3637_00225 ENOG4108IG5 Transcriptional regulator Ami3637_00230 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) Ami3637_00255 ENOG4105DY9 regulatoR Ami3637_00260 ENOG4108V4B ThiJ pfpI Ami3637_00275 ENOG4107RMF Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity) Ami3637_00280 ENOG4107QN2 dihydrolipoyl dehydrogenase Ami3637_00290 ENOG4105NTK Transcriptional repressor Mpra Ami3637_00345 ENOG4106V2I dimethylaminohydrolase Ami3637_00390 ENOG4105NA0 Transcriptional regulator Ami3637_00400 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) Ami3637_00410 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) Ami3637_00415 ENOG4105JFG SpoIID LytB domain protein Ami3637_00430 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) Ami3637_00435 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) Ami3637_00440 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) Ami3637_00455 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) Ami3637_00460 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) Ami3637_00465 ENOG4105D1H recombination factor protein RarA Ami3637_00520 ENOG4105CKD glutathione-regulated potassium-efflux system protein Ami3637_00525 ENOG4105BZU Histidine kinase Ami3637_00530 ENOG4105DPZ Two component transcriptional regulator (Winged helix family Ami3637_00545 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit Ami3637_00555 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) Ami3637_00565 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) Ami3637_00575 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) Ami3637_00580 ENOG4105KG3 cytidine deaminase Ami3637_00590 ENOG4105C9A Phoh family Ami3637_00595 ENOG4105EI1 sporulation protein yqfd Ami3637_00605 ENOG4105C6T cysteine synthase Ami3637_00620 ENOG4105VCC 30S ribosomal protein S21 Ami3637_00625 ENOG4107YU2 histidine triad (hIT) protein Ami3637_00630 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) Ami3637_00635 ENOG4105KWG Pfam:DUF1696 Ami3637_00640 ENOG4107BJW polysaccharide deacetylase Ami3637_00650 ENOG4105MAX Superoxide reductase Ami3637_00655 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) Ami3637_00660 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) Ami3637_00665 ENOG41090E6 transcriptional regulator MERR family Ami3637_00680 ENOG4105KJF protein tyrosine phosphatase Ami3637_00700 ENOG4107XID 2'-5' rna ligase Ami3637_00705 ENOG4105C45 hydrogenase expression formation protein (HypE) Ami3637_00715 ENOG4105WRB Hydrogenase assembly chaperone hypC hupF Ami3637_00725 ENOG410855V Acylphosphatase Ami3637_00745 ENOG4108HM5 NADH-ubiquinone oxidoreductase chain 49kDa Ami3637_00755 ENOG4105C47 NADH ubiquinone oxidoreductase 20 kda subunit Ami3637_00765 ENOG4105D65 subunit l Ami3637_00775 ENOG4105C3U ABC transporter Ami3637_00780 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component Ami3637_00810 ENOG4105VPX protein, conserved in bacteria Ami3637_00820 ENOG4105BZU Histidine kinase Ami3637_00845 ENOG4107FQ9 ethanolamine ammonia-lyase Ami3637_00850 ENOG4105CPD ethanolamine ammonia-lyase Ami3637_00855 ENOG4105RAK Histidine kinase Ami3637_00860 ENOG4105WH1 Two component transcriptional regulator luxr family Ami3637_00870 ENOG4107ZHV Transcriptional regulator Ami3637_00880 ENOG4105KNY Microcompartments protein Ami3637_00885 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami3637_00890 ENOG4105C0A alcohol dehydrogenase Ami3637_00895 ENOG4105KNY Microcompartments protein Ami3637_00910 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) Ami3637_00925 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml Ami3637_00930 ENOG4108PFF ethanolamine utilization cobalamin adenosyltransferase Ami3637_00935 ENOG4106D67 ethanolamine utilization protein Ami3637_00945 ENOG4105KTW ethanolamine utilization protein Ami3637_00950 ENOG4105M3W utilization protein Ami3637_00955 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Ami3637_00965 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Ami3637_00970 ENOG4105EEI dihydropteroate synthase Ami3637_00975 ENOG4105KFW domain protein Ami3637_00990 ENOG4105CFG Acts as a chaperone (By similarity) Ami3637_01000 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) Ami3637_01005 ENOG4108IV0 ABC, transporter Ami3637_01010 ENOG4105C0Z ABC transporter Ami3637_01015 ENOG4105CF8 branched-chain amino acid ABC transporter, permease Ami3637_01020 ENOG4105C32 Amino acid ABC transporter (Permease) Ami3637_01040 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) Ami3637_01045 ENOG4105BZG amino acid carrier protein Ami3637_01080 ENOG4105CSA Coproporphyrinogen iii oxidase Ami3637_01115 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) Ami3637_01120 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) Ami3637_01125 ENOG4105W4W Transcriptional regulator Ami3637_01140 ENOG4105CEU Arginine dihydrolase Ami3637_01145 ENOG4107VHA regulatoR Ami3637_01150 ENOG4105D5Q Arginine ornithine antiporter Ami3637_01155 ENOG4105D6E homoserine dehydrogenase Ami3637_01160 ENOG4108K88 Membrane Ami3637_01165 ENOG4105FR1 rard protein Ami3637_01170 ENOG4105DFD Na H antiporter Ami3637_01185 ENOG4105DPN Oligoendopeptidase f Ami3637_01190 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) Ami3637_01195 ENOG4105C34 Pseudouridine synthase Ami3637_01200 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_01215 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate Ami3637_01225 ENOG4105C9U ATP-dependent DNA helicase RecQ Ami3637_01265 ENOG4105CMU LysR family (Transcriptional regulator Ami3637_01305 ENOG410827H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity) Ami3637_01330 ENOG4105KVH Transcriptional regulator Ami3637_01355 ENOG4108UB4 uncharacterized protein ygjQ Ami3637_01380 ENOG4107QMH DNA methylase Ami3637_01405 ENOG4108JQ9 ABC transporter Ami3637_01410 ENOG4105DIH basic membrane Ami3637_01415 ENOG4105K4I Scp-like extracellular Ami3637_01420 ENOG4105P8F nudix hydrolase Ami3637_01425 ENOG4108TVT permease Ami3637_01440 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) Ami3637_01465 ENOG4105KGF protein, YerC YecD Ami3637_01470 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) Ami3637_01490 ENOG4108EKI Dehydrogenase Ami3637_01510 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami3637_01515 ENOG4105KNY Microcompartments protein Ami3637_01520 ENOG4108WT6 Carbon dioxide concentrating mechanism protein Ami3637_01530 ENOG41084PW diol glycerol dehydratase reactivating factor large subunit Ami3637_01535 ENOG4108ZFT Dehydratase small subunit Ami3637_01540 ENOG4105YCI dehydratase medium subunit Ami3637_01550 ENOG4105EHR propanediol utilization protein pduB Ami3637_01555 ENOG41075H3 AraC family transcriptional regulator Ami3637_01570 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) Ami3637_01575 ENOG4105DR5 peptidase Ami3637_01580 ENOG4105CRP Part of the ABC transporter FtsEX involved in Ami3637_01585 ENOG4105CAK Cell division ATP-binding protein ftsE Ami3637_01605 ENOG4108IUS Transketolase Ami3637_01610 ENOG4108HHA Transketolase Ami3637_01635 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) Ami3637_01640 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) Ami3637_01645 ENOG4105CJW magnesium transporter Ami3637_01665 ENOG4105D82 Glutamate dehydrogenase Ami3637_01670 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) Ami3637_01685 ENOG41065RQ ADP-ribosylation crystallin J1 Ami3637_01690 ENOG4108TFM Kinase, PfkB family Ami3637_01695 ENOG4108TFM Kinase, PfkB family Ami3637_01700 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) Ami3637_01705 ENOG4105D38 putrescine abc transporter Ami3637_01710 ENOG4105F38 ABC transporter, permease Ami3637_01720 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami3637_01725 ENOG4107R7I amino acid Ami3637_01730 ENOG4107RUE extracellular solute-binding protein family 1 Ami3637_01735 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) Ami3637_01780 ENOG4105CG5 Glycosyl transferase (Group 1 Ami3637_01875 ENOG4105CI3 gtp-binding protein typa Ami3637_01900 ENOG4105CSA Coproporphyrinogen iii oxidase Ami3637_01905 ENOG4105VUC UPF0237 protein Ami3637_01930 ENOG4105DE9 3-keto-5-aminohexanoate cleavage enzyme Ami3637_01935 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) Ami3637_01945 ENOG4105D4A Cell wall formation (By similarity) Ami3637_01960 ENOG4105KT7 mgtC SapB transporter Ami3637_01975 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_01980 ENOG4108UNF response regulator Ami3637_01985 ENOG4105BZU Histidine kinase Ami3637_02070 ENOG4107QJE Chromosome Partitioning Protein Ami3637_02140 ENOG4105CNW domain protein Ami3637_02145 ENOG4105C1G acyl-Coa dehydrogenase Ami3637_02185 ENOG4105H67 Protein of unknown function (DUF421) Ami3637_02195 ENOG4105X71 Membrane Ami3637_02200 ENOG41082I2 s4 domain protein Ami3637_02205 ENOG4105K70 DNA-binding protein Ami3637_02210 ENOG4105DXN mazG family Ami3637_02220 ENOG41080U2 Amidohydrolase family Ami3637_02225 ENOG4108M14 stage v sporulation protein t Ami3637_02230 ENOG4108JA2 transcriptioN-repair coupling factor Ami3637_02235 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) Ami3637_02245 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) Ami3637_02250 ENOG4105DFU Cell wall formation (By similarity) Ami3637_02255 ENOG4105DFT pur operon repressor Ami3637_02260 ENOG4105K4W Could be involved in septation (By similarity) Ami3637_02265 ENOG4105C3M thioredoxin reductase Ami3637_02280 ENOG4105E4C Lytic transglycosylase catalytic Ami3637_02295 ENOG4105CJN penicillin-binding protein Ami3637_02305 ENOG4105FQP Beta-lactamase Ami3637_02310 ENOG4107T14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) Ami3637_02320 ENOG4105JVQ RNA Polymerase Ami3637_02330 ENOG4105D3R alkyl hydroperoxide reductase Ami3637_02350 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) Ami3637_02355 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) Ami3637_02360 ENOG4105SKN orotidine 5''-phosphate decarboxylase Ami3637_02380 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) Ami3637_02470 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation Ami3637_02475 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation Ami3637_02485 ENOG4105HIR S-layer domain protein Ami3637_02535 ENOG4105CIN aminoacyl-histidine dipeptidase Ami3637_02555 ENOG4105DZ0 fad dependent oxidoreductase Ami3637_02560 ENOG4105CBX hi0933 family Ami3637_02590 ENOG4105C1J atp-dependent rna helicase Ami3637_02595 ENOG4105BZU Histidine kinase Ami3637_02605 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase Ami3637_02610 ENOG41090R7 Ferric uptake Ami3637_02625 ENOG4105DSE periplasmic solute binding protein Ami3637_02655 ENOG4108Z4T Peptidase M50 Ami3637_02660 ENOG4105K4H Nlp p60 protein Ami3637_02665 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) Ami3637_02695 ENOG4108V3W Chemotaxis protein, CheW Ami3637_02710 ENOG4105CYW agmatinase Ami3637_02715 ENOG4105YVS arsR family transcriptional regulator Ami3637_02720 ENOG4107S21 permease Ami3637_02740 ENOG4105CYW agmatinase Ami3637_02755 ENOG4105CI2 imidazolone-5-propionate hydrolase Ami3637_02760 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) Ami3637_02795 ENOG4105CKM Branched-chain carboxylic acid kinase Ami3637_02800 ENOG4107RE7 phosphate butyryltransferase Ami3637_02850 ENOG410906S phage-like element pbsx protein xkdt Ami3637_02855 ENOG41066EA baseplate J family protein Ami3637_02980 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase Ami3637_02990 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) Ami3637_02995 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) Ami3637_03000 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) Ami3637_03040 ENOG4105EFZ amidohydrolase Ami3637_03050 ENOG4108IQI permease Ami3637_03060 ENOG4105C87 Aminotransferase class I and II Ami3637_03065 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) Ami3637_03070 ENOG4105DZ1 carboxypeptidase Ami3637_03085 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) Ami3637_03110 ENOG4108JIC nucleoside recognition domain protein Ami3637_03120 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A Ami3637_03125 ENOG4108JUA Transcriptional regulator Ami3637_03135 ENOG4105E5Q amino acid AbC transporter Ami3637_03140 ENOG4107R0W ABC transporter Ami3637_03150 ENOG4108ZJ4 polysaccharide deacetylase Ami3637_03165 ENOG4105CBD Diacylglycerol kinase Ami3637_03175 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase Ami3637_03180 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) Ami3637_03190 ENOG4105BZU Histidine kinase Ami3637_03205 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) Ami3637_03210 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) Ami3637_03220 ENOG4107PPM cobalt chelatase Ami3637_03230 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase Ami3637_03235 ENOG4105D52 delta-aminolevulinic acid dehydratase Ami3637_03240 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) Ami3637_03245 ENOG410908R Methenyltetrahydrofolate cyclohydrolase Ami3637_03250 ENOG4105CKU formyltetrahydrofolate synthetase Ami3637_03255 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) Ami3637_03260 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) Ami3637_03265 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) Ami3637_03270 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami3637_03280 ENOG4108YZ4 nudix hydrolase Ami3637_03285 ENOG4105II7 pyrroline-5-carboxylate reductase Ami3637_03290 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) Ami3637_03305 ENOG4105WMM Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity) Ami3637_03320 ENOG4105C5H ABC transporter Ami3637_03330 ENOG4105MCT stage V sporulation protein S Ami3637_03380 ENOG4105KNY Microcompartments protein Ami3637_03385 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami3637_03390 ENOG4105C0A alcohol dehydrogenase Ami3637_03395 ENOG4105KNY Microcompartments protein Ami3637_03410 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) Ami3637_03430 ENOG4105KTW ethanolamine utilization protein Ami3637_03435 ENOG4105M3W utilization protein Ami3637_03440 ENOG4105F1A Pyruvate formate-lyase Ami3637_03445 ENOG4105C6N Formate acetyltransferase Ami3637_03450 ENOG4105C0A alcohol dehydrogenase Ami3637_03460 ENOG4105KNY Microcompartments protein Ami3637_03495 ENOG41086D8 Transcriptional regulator Ami3637_03500 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) Ami3637_03505 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) Ami3637_03520 ENOG4108UYE Lactoylglutathione lyase Ami3637_03535 ENOG4106P55 Transcriptional regulator Ami3637_03540 ENOG4105BZ1 (ABC) transporter Ami3637_03545 ENOG4105BZ1 (ABC) transporter Ami3637_03560 ENOG4105CHM Aminotransferase Ami3637_03610 ENOG4105F8V Hydrolase, tatD family Ami3637_03625 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component Ami3637_03635 ENOG4108V2W Carbonate dehydratase Ami3637_03640 ENOG4108HM4 ABC transporter Ami3637_03645 ENOG4105D38 putrescine abc transporter Ami3637_03650 ENOG4105F38 ABC transporter, permease Ami3637_03655 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) Ami3637_03690 ENOG4105JVQ RNA Polymerase Ami3637_03700 ENOG4108Q5Y Membrane Ami3637_03720 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) Ami3637_03765 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) Ami3637_03775 ENOG4105D7N magnesium and cobalt transport protein CorA Ami3637_03790 ENOG4108NEV two component transcriptional regulator, LytTR family Ami3637_03805 ENOG4105DHT Metal Dependent Phosphohydrolase Ami3637_03830 ENOG4105D2X ABC transporter substrate-binding protein Ami3637_03835 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component Ami3637_03870 ENOG41067QW Transcriptional regulator Ami3637_03885 ENOG4105BZU Histidine kinase Ami3637_03890 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_03910 ENOG4105BZU Histidine kinase Ami3637_03915 ENOG4107Y70 Heat shock protein Ami3637_03930 ENOG410630P Transcriptional regulator Ami3637_03940 ENOG4108AEY RNA polymerase sigma factor Ami3637_03955 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_03970 ENOG4105C59 p-type ATPase Ami3637_03975 ENOG410681U heavy metal transport detoxification protein Ami3637_03995 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase Ami3637_04000 ENOG4105C85 amino acid Ami3637_04010 ENOG4108IQI permease Ami3637_04025 ENOG4108Z6Z Transcriptional regulator Ami3637_04045 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_04060 ENOG4105EMN RNA polymerase sigma factor Ami3637_04080 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) Ami3637_04085 ENOG4105DTC 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase Ami3637_04125 ENOG4105C0X amino acid Ami3637_04130 ENOG4105C85 amino acid Ami3637_04150 ENOG4105ER2 Ompa motb domain protein Ami3637_04155 ENOG4105E14 MotA TolQ exbB proton channel Ami3637_04160 ENOG4105C6T cysteine synthase Ami3637_04175 ENOG4107TXC Transcriptional regulator Ami3637_04195 ENOG4105KVH Transcriptional regulator Ami3637_04280 ENOG41069D7 Methyl-accepting chemotaxis Ami3637_04285 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_04290 ENOG4105C5H ABC transporter Ami3637_04300 ENOG4108WS4 fmn reductase Ami3637_04325 ENOG4105JVQ RNA Polymerase Ami3637_04340 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase Ami3637_04345 ENOG4108SWU Histidine kinase Ami3637_04350 ENOG4105DPZ Two component transcriptional regulator (Winged helix family Ami3637_04360 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_04365 ENOG4105EB3 Histidine kinase Ami3637_04380 ENOG4107U9B transcriptional regulator Ami3637_04385 ENOG4108VW9 Membrane Ami3637_04430 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) Ami3637_04435 ENOG41082UD thioesterase Superfamily protein Ami3637_04455 ENOG4105VMP Transcriptional regulator Ami3637_04505 ENOG4105CGK Exodeoxyribonuclease III Ami3637_04535 ENOG410620I Diguanylate cyclase Ami3637_04550 ENOG4106NZI LysR family Transcriptional regulator Ami3637_04555 ENOG4108RNG Permease of the drug metabolite transporter Ami3637_04605 ENOG4105WEF catalase Ami3637_04660 ENOG4105GH9 galactofuranosyltransferase Ami3637_04705 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 Ami3637_04710 ENOG4105C9U ATP-dependent DNA helicase RecQ Ami3637_04715 ENOG4107QSA Oxaloacetate decarboxylase Ami3637_04720 ENOG4105VRS hydrolase family 18 Ami3637_04735 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) Ami3637_04740 ENOG4108R5S membrane Ami3637_04765 ENOG4107QSE Dipeptidase Ami3637_04785 ENOG4105G9B Transcriptional regulator Ami3637_04800 ENOG4105IIU Aminopeptidase Ami3637_04810 ENOG4105CN5 Metallo-Beta-Lactamase Ami3637_04815 ENOG4107BJW polysaccharide deacetylase Ami3637_04820 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_04825 ENOG4105BZU Histidine kinase Ami3637_04845 ENOG4105C8M UPF0272 protein Ami3637_04860 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) Ami3637_04885 ENOG4108UMN azlc family Ami3637_04905 ENOG4107QP7 CoA-transferase subunit A Ami3637_04920 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_04930 ENOG4108Z29 Flavodoxin Ami3637_04960 ENOG4105D58 Diguanylate phosphodiesterase Ami3637_04980 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) Ami3637_04985 ENOG4105CZX twitching motility protein Ami3637_05025 ENOG4108RN7 integral membrane protein Ami3637_05040 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami3637_05045 ENOG4108UGV hypoxanthine phosphoribosyltransferase Ami3637_05055 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) Ami3637_05060 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) Ami3637_05075 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation Ami3637_05080 ENOG4105I7R Adenylate cyclase Ami3637_05110 ENOG4107Y7X LytTR Ami3637_05120 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin Ami3637_05145 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) Ami3637_05155 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) Ami3637_05170 ENOG4108Z3G 3H domain protein Ami3637_05175 ENOG4105CY0 Metallo-Beta-Lactamase Ami3637_05180 ENOG4105BZ8 glutamate synthase Ami3637_05185 ENOG4105CDJ oxidoreductase FAD NAD(P)-binding domain protein Ami3637_05195 ENOG4107SVV electron transport complex, RnfABCDGE type, B subunit Ami3637_05205 ENOG4105CK1 PTS System Ami3637_05240 ENOG4105E9Q Acyl-transferase Ami3637_05265 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) Ami3637_05280 ENOG4108ZT0 50S ribosomal protein l17 Ami3637_05290 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) Ami3637_05295 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) Ami3637_05300 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) Ami3637_05310 ENOG41067V7 50S ribosomal protein L36 Ami3637_05330 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) Ami3637_05335 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) Ami3637_05340 ENOG4105VPB 50S ribosomal protein L30 Ami3637_05350 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) Ami3637_05360 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) Ami3637_05365 ENOG41082QR Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) Ami3637_05370 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits Ami3637_05375 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) Ami3637_05380 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) Ami3637_05385 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal Ami3637_05390 ENOG41082SA 50s ribosomal protein l29 Ami3637_05395 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) Ami3637_05400 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) Ami3637_05405 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) Ami3637_05410 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) Ami3637_05425 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) Ami3637_05435 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) Ami3637_05440 ENOG4105DD7 kinase (PfkB family Ami3637_05450 ENOG4105WG9 Conserved Protein Ami3637_05460 ENOG4105DB7 PHP domain protein Ami3637_05465 ENOG4105C0B DNA polymerase III (alpha subunit) Ami3637_05470 ENOG4107S0N DJ-1 family Ami3637_05490 ENOG4108JQ9 ABC transporter Ami3637_05520 ENOG4107RT6 flagellar hook-associated Ami3637_05540 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_05550 ENOG4107PHP CheC --inhibitor of MCP methylation Ami3637_05560 ENOG4105CGA flagellar basal-body rod protein FlgG Ami3637_05565 ENOG4108JQA flagellar Ami3637_05580 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) Ami3637_05590 ENOG4105CBS Chea signal transduction histidine kinase Ami3637_05595 ENOG4105BZU Histidine kinase Ami3637_05600 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) Ami3637_05605 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) Ami3637_05620 ENOG4105E1Q flagellar hook-associated protein Ami3637_05635 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) Ami3637_05675 ENOG4107R51 Glycosyl transferase, family 2 Ami3637_05680 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) Ami3637_05685 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) Ami3637_05690 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) Ami3637_05695 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) Ami3637_05710 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) Ami3637_05725 ENOG4105FAW cDP-glucose 4,6-dehydratase Ami3637_05730 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase Ami3637_05750 ENOG4105D00 flagellar biosynthetic protein flhB Ami3637_05760 ENOG4105VS8 Flagellar biosynthetic protein fliq Ami3637_05765 ENOG4105CN7 Flagellar biosynthetic protein FliP Ami3637_05775 ENOG4107YTP response regulator receiver protein Ami3637_05780 ENOG4105DD5 Flagellar motor switch protein Ami3637_05790 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) Ami3637_05800 ENOG4108JQA flagellar Ami3637_05810 ENOG4105W00 Flagellar hook capping protein Ami3637_05835 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) Ami3637_05840 ENOG4107U2N Flagellar M-ring protein Ami3637_05850 ENOG4108ZC9 flagellar basal-body rod protein flgc Ami3637_05865 ENOG41068XD UPF0473 protein Ami3637_05870 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) Ami3637_05875 ENOG4105DZ1 carboxypeptidase Ami3637_05880 ENOG4105E3H phosphoglycerate mutase Ami3637_05885 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) Ami3637_05890 ENOG4108JQ1 Dehydrogenase Ami3637_05905 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) Ami3637_05910 ENOG4108UI1 Probably functions as a manganese efflux pump (By similarity) Ami3637_05920 ENOG4105C5I Dehydrogenase Ami3637_05985 ENOG4108Z5K methylglyoxal synthase Ami3637_05995 ENOG4107VMI polysaccharide deacetylase Ami3637_06020 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) Ami3637_06040 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) Ami3637_06045 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) Ami3637_06055 ENOG4105C8B TIGR00159 family Ami3637_06070 ENOG4105MJ2 Competence protein Ami3637_06075 ENOG4105C7H Helicase, RecD TraA family Ami3637_06090 ENOG4105BZU Histidine kinase Ami3637_06095 ENOG4105BZU Histidine kinase Ami3637_06110 ENOG4107RBB ABC transporter, permease Ami3637_06120 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami3637_06135 ENOG4108YZG isomerase Ami3637_06140 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) Ami3637_06150 ENOG41082DI 50s ribosomal protein l31 Ami3637_06155 ENOG4105DJ2 Major Facilitator Superfamily Ami3637_06160 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) Ami3637_06165 ENOG4105CBJ Metal-dependent enzyme Ami3637_06170 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) Ami3637_06180 ENOG4108RCF TRANSCRIPTIONal Ami3637_06185 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase Ami3637_06190 ENOG4107QYV phosphohexose isomerase Ami3637_06225 ENOG4105DQ6 Transposase Ami3637_06230 ENOG4105CMR udp-glucose 4-epimerase Ami3637_06250 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) Ami3637_06305 ENOG4108UW5 maltose o-acetyltransferase Ami3637_06320 ENOG4107S6X Glycosyl transferase, family 2 Ami3637_06335 ENOG4105MFV ABC-2 type transporter Ami3637_06340 ENOG4105C1B dTDP-glucose 4-6-dehydratase Ami3637_06350 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) Ami3637_06355 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) Ami3637_06360 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) Ami3637_06365 ENOG4108PQP glycosyl transferase group 1 Ami3637_06385 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase Ami3637_06390 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) Ami3637_06405 ENOG4108P1X synthase Ami3637_06410 ENOG4105CHR reductase Ami3637_06425 ENOG4105D3Q Sugar transferase Ami3637_06435 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase Ami3637_06445 ENOG4105C5E polysaccharide biosynthesis protein Ami3637_06450 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase Ami3637_06465 ENOG4107T8Q Glycosyl transferase (Group 1 Ami3637_06475 ENOG4105CJR Integral membrane protein (MviN Ami3637_06480 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) Ami3637_06505 ENOG4105CK7 Sodium proline symporter Ami3637_06515 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) Ami3637_06530 ENOG4108JJB ABC transporter Ami3637_06555 ENOG4105CN1 protease Ami3637_06570 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) Ami3637_06580 ENOG4105C0H protease Ami3637_06585 ENOG4108ZXQ stage ii sporulation protein r Ami3637_06595 ENOG4107PHP CheC --inhibitor of MCP methylation Ami3637_06600 ENOG4105DRR Transcriptional regulator, GntR family Ami3637_06605 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) Ami3637_06610 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) Ami3637_06620 ENOG4108Z6B deaminase Ami3637_06625 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase Ami3637_06650 ENOG4105FGV Chromate Ami3637_06685 ENOG4105CIH Imidazole acetol-phosphate transaminase Ami3637_06770 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami3637_06795 ENOG4105C83 adenylosuccinate lyase Ami3637_06810 ENOG4105CUZ uba thif-type nad fad binding protein Ami3637_06835 ENOG4105F1A Pyruvate formate-lyase Ami3637_06840 ENOG4105C6N Formate acetyltransferase Ami3637_06845 ENOG4108JUB Transcriptional regulator Ami3637_06855 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) Ami3637_06865 ENOG4105DRR Transcriptional regulator, GntR family Ami3637_06870 ENOG4105CCS Glutamate formiminotransferase Ami3637_06885 ENOG4105CGP Urocanate hydratase Ami3637_06890 ENOG4105C84 Histidine ammonia-lyase Ami3637_06915 ENOG4105CT4 transporter Ami3637_06960 ENOG4105C7B Threonine dehydratase Ami3637_06985 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase Ami3637_06990 ENOG4108ZP8 Acetolactate synthase small subunit Ami3637_06995 ENOG4105C7K acetolactate synthase Ami3637_07000 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) Ami3637_07010 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami3637_07015 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami3637_07020 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami3637_07025 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami3637_07035 ENOG4105BZU Histidine kinase Ami3637_07040 ENOG4108JPM phospho-2-dehydro-3-deoxyheptonate aldolase Ami3637_07050 ENOG4105D49 3-dehydroquinate synthase Ami3637_07055 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase Ami3637_07060 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase Ami3637_07070 ENOG4105E2X shikimate dehydrogenase Ami3637_07085 ENOG4105KAF membrAne Ami3637_07095 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) Ami3637_07100 ENOG4105KME endoribonuclease L-psp Ami3637_07105 ENOG4108Z66 YbaK ebsC protein Ami3637_07145 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) Ami3637_07180 ENOG4105BZU Histidine kinase Ami3637_07190 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_07200 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_07205 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin Ami3637_07210 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin Ami3637_07225 ENOG4107QSE Dipeptidase Ami3637_07230 ENOG4107S6Z Na H antiporter Ami3637_07250 ENOG4105DBI uridine monophosphokinase Ami3637_07255 ENOG4105DR5 peptidase Ami3637_07275 ENOG4105CDU Replicative dna helicase Ami3637_07280 ENOG4105K9Q Binds to the 23S rRNA (By similarity) Ami3637_07285 ENOG4105BZR domain protein Ami3637_07295 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) Ami3637_07300 ENOG4108UUM single-stranded DNA-binding protein Ami3637_07320 ENOG4105UIB (ABC) transporter Ami3637_07325 ENOG4108JQ9 ABC transporter Ami3637_07330 ENOG4107TFB basic membrane Ami3637_07365 ENOG4108ZEY Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) Ami3637_07370 ENOG410841Q phosphoesterase PA-phosphatase related protein Ami3637_07380 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) Ami3637_07410 ENOG4105DA5 (ABC) transporter Ami3637_07415 ENOG4107AYK membrAne Ami3637_07420 ENOG4105C31 Tryptophanyl-tRNA synthetase Ami3637_07435 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Ami3637_07440 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) Ami3637_07450 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) Ami3637_07455 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) Ami3637_07465 ENOG4105VG0 50S ribosomal protein l34 Ami3637_07480 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins Ami3637_07485 ENOG4108Z7S Single-stranded nucleic acid binding R3H domain-containing protein Ami3637_07490 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) Ami3637_07495 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) Ami3637_07500 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) Ami3637_07510 ENOG4107QJE Chromosome Partitioning Protein Ami3637_07515 ENOG4105FA0 parb-like partition protein Ami3637_07520 ENOG410696E Membrane Ami3637_07525 ENOG4107X8C Efflux transporter RND family MFP subunit Ami3637_07530 ENOG4105C19 ABC transporter Ami3637_07535 ENOG4107RBB ABC transporter, permease Ami3637_07545 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family Ami3637_07605 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) Ami3637_07630 ENOG4105BZU Histidine kinase Ami3637_07635 ENOG4105CXN decarboxylase Ami3637_07640 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) Ami3637_07645 ENOG4105CYW agmatinase Ami3637_07665 ENOG4105DFD Na H antiporter Ami3637_07670 ENOG4108JUB Transcriptional regulator Ami3637_07675 ENOG4105DCF alanine dehydrogenase Ami3637_07685 ENOG4108JUB Transcriptional regulator Ami3637_07690 ENOG4108KR4 dihydrodipicolinate reductase Ami3637_07695 ENOG4105Z5Q Ami3637_07700 ENOG4107RH1 pyridoxal-5'-phosphate-dependent protein beta subunit Ami3637_07705 ENOG4105KIJ D-ornithine aminomutase S component Ami3637_07710 ENOG4105EQ5 D-Lysine 5,6-aminomutase alpha subunit Ami3637_07725 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_07730 ENOG41082IR Excinuclease ABC C subunit domain protein Ami3637_07740 ENOG4107R88 Chemotaxis protein (CheV) Ami3637_07745 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) Ami3637_07785 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) Ami3637_07800 ENOG4107EF8 Glycosyl transferase (Group 1 Ami3637_07805 ENOG4107EF8 Glycosyl transferase (Group 1 Ami3637_07845 ENOG4105DZW Dipeptidase Ami3637_07855 ENOG4105C5R Aminotransferase Ami3637_07860 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) Ami3637_07875 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) Ami3637_07885 ENOG4105EEX Two component transcriptional regulator (Winged helix family Ami3637_07890 ENOG4105C08 Histidine kinase Ami3637_07925 ENOG4105DZ1 carboxypeptidase Ami3637_07930 ENOG4106M28 alanine racemase domain protein Ami3637_07935 ENOG4105CDA abc transporter atp-binding protein Ami3637_07940 ENOG4105C28 cystathionine Ami3637_07945 ENOG4105EAB amino acid AbC transporter Ami3637_07950 ENOG4105DRP amino acid AbC transporter Ami3637_07960 ENOG4108JUB Transcriptional regulator Ami3637_07965 ENOG4107SC7 Inner membrane transporter yjeM Ami3637_07970 ENOG4105EFZ amidohydrolase Ami3637_08070 ENOG4105DJZ UPF0182 protein Ami3637_08080 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) Ami3637_08130 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_08140 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein Ami3637_08145 ENOG4105E0C molybdate abc transporter Ami3637_08150 ENOG4107P0T Selenium-dependent molybdenum hydroxylase system protein, YqeB family Ami3637_08160 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) Ami3637_08165 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_08170 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_08175 ENOG41082YX Transcriptional regulator, arsr family Ami3637_08180 ENOG4105C59 p-type ATPase Ami3637_08185 ENOG4105DFD Na H antiporter Ami3637_08190 ENOG4105EFZ amidohydrolase Ami3637_08195 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) Ami3637_08205 ENOG4105CMU LysR family (Transcriptional regulator Ami3637_08210 ENOG4107QTR Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity) Ami3637_08220 ENOG4108UQQ Electron transport complex Ami3637_08225 ENOG4105DZB Electron transport complex Ami3637_08230 ENOG4105DGN Electron transport complex Ami3637_08235 ENOG4107SVV electron transport complex, RnfABCDGE type, B subunit Ami3637_08300 ENOG4105CJ1 ABC, transporter Ami3637_08320 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) Ami3637_08350 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) Ami3637_08370 ENOG4105D78 K07001 NTE family protein Ami3637_08405 ENOG4108JJB ABC transporter Ami3637_08420 ENOG4105E5G Alpha beta hydrolase fold Ami3637_08435 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) Ami3637_08450 ENOG4105C8U phosphate abc transporter Ami3637_08455 ENOG4105E2Z phosphate ABC transporter (Permease Ami3637_08460 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) Ami3637_08470 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_08485 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase Ami3637_08490 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) Ami3637_08500 ENOG4105CHU acetyl-coa acetyltransferase Ami3637_08510 ENOG4106PMH Extracellular solute-binding protein family 3 Ami3637_08515 ENOG4105E5Q amino acid AbC transporter Ami3637_08520 ENOG4105CDA abc transporter atp-binding protein Ami3637_08545 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase Ami3637_08555 ENOG4105C6K Malic enzyme Ami3637_08560 ENOG4105BZU Histidine kinase Ami3637_08570 ENOG410812S Rna-binding protein Ami3637_08580 ENOG4108Z6B deaminase Ami3637_08585 ENOG4105ESV Glycosyl transferase, family 4 Ami3637_08590 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase Ami3637_08595 ENOG4107QJQ Mate efflux family protein Ami3637_08605 ENOG4107WJT it plays a direct role in the translocation of protons across the membrane (By similarity) Ami3637_08610 ENOG4105VH4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) Ami3637_08615 ENOG4107ZFM Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) Ami3637_08620 ENOG4107YZM F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) Ami3637_08625 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) Ami3637_08630 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) Ami3637_08635 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) Ami3637_08640 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) Ami3637_08650 ENOG4105BZU Histidine kinase Ami3637_08670 ENOG4105CE1 Ferrous iron transport protein b Ami3637_08675 ENOG4105E4C Lytic transglycosylase catalytic Ami3637_08690 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) Ami3637_08700 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) Ami3637_08720 ENOG4105DZ1 carboxypeptidase Ami3637_08735 ENOG4105FKZ Methyl-accepting chemotaxis Ami3637_08760 ENOG41067MG lrgb family Ami3637_08770 ENOG41073TP transcriptional regulator Ami3637_08780 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) Ami3637_08785 ENOG4105C8V SAICAR synthetase Ami3637_08795 ENOG4105CXB phosphoribosylaminoimidazole synthetase Ami3637_08800 ENOG4108V3E phosphoribosylglycinamide formyltransferase Ami3637_08915 ENOG4105BZU Histidine kinase Ami3637_08935 ENOG4105ER2 Ompa motb domain protein Ami3637_08940 ENOG4105FE9 pseudouridine synthase Ami3637_08960 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_08965 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase Ami3637_08970 ENOG4108Z5V transcriptional regulator, merr family Ami3637_08975 ENOG4108IG5 Transcriptional regulator Ami3637_08985 ENOG4105CW7 secretion protein, HlyD family Ami3637_08990 ENOG4105C0R drug resistance transporter emrb qaca subfamily Ami3637_08995 ENOG4108JUB Transcriptional regulator Ami3637_09010 ENOG4108IQI permease Ami3637_09050 ENOG4105BZU Histidine kinase Ami3637_09055 ENOG4108EE5 Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami3637_09065 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) Ami3637_09065 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) Ami3637_09080 ENOG4105CIN aminoacyl-histidine dipeptidase Ami3637_09085 ENOG4105CIN aminoacyl-histidine dipeptidase Ami3637_09095 ENOG4105CH7 arginosuccinase Ami3637_09110 ENOG4105C7W Xanthine dehydrogenase Ami3637_09120 ENOG4108UYI beta-alanyl-CoA ammonia lyase Ami3637_09130 ENOG4105FRY Dehydrogenase Ami3637_09135 ENOG4105FRY Dehydrogenase Ami3637_09140 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein Ami3637_09150 ENOG4105C98 muts2 protein Ami3637_09155 ENOG4105EQ5 D-Lysine 5,6-aminomutase alpha subunit Ami3637_09160 ENOG4107CHF 5,6-aminomutase beta subunit Ami3637_09165 ENOG4107QP7 CoA-transferase subunit A Ami3637_09175 ENOG4107R88 Chemotaxis protein (CheV) Ami3637_09195 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase Ami3637_09215 ENOG4105CFH Aspartokinase Ami3637_09220 ENOG4105CVG Homoserine O-transsuccinylase Ami3637_09225 ENOG4105HEE Binding Domain protein Ami3637_09230 ENOG4108JU6 CBS domain protein Ami3637_09235 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving Ami3637_09255 ENOG4107XGZ Hydrolase Ami3637_09260 ENOG4105BZF Glycosyl transferase (Group 1 Ami3637_09265 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) Ami3637_09275 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase Ami3637_09280 ENOG4105CHR reductase Ami3637_09290 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) Ami3637_09305 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination Ami3637_09310 ENOG4105C5N The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination Ami3637_09365 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer Ami3637_09370 ENOG4105WH1 Two component transcriptional regulator luxr family Ami3637_09505 ENOG4105DHM ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity) Ami3637_09510 ENOG4105WH1 Two component transcriptional regulator luxr family Ami3637_09525 ENOG4105M3W utilization protein Ami3637_09545 ENOG4105CPD ethanolamine ammonia-lyase Ami3637_09555 ENOG4106D67 ethanolamine utilization protein Ami3637_09560 ENOG4105KNY Microcompartments protein Ami3637_09570 ENOG4105KNY Microcompartments protein Ami3637_09575 ENOG4105KNY Microcompartments protein Ami3637_09585 ENOG4108VPX Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity) Ami3637_09595 ENOG4105WVM ethanolamine utilization protein EutN carboxysome structural protein Ccml Ami3637_09625 ENOG4107RWI ethanolamine utilization protein eutJ Ami3637_09655 ENOG4105IIU Aminopeptidase Ami3637_09665 ENOG4105CEY Amp-dependent synthetase and ligase Ami3637_09670 ENOG4108IQE Amp-dependent synthetase and ligase Ami3637_09675 ENOG4106M28 alanine racemase domain protein Ami3637_09680 ENOG410631K Membrane Ami3637_09685 ENOG4105CJZ response regulator Ami3637_09690 ENOG4105EWM Histidine kinase Ami3637_09705 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_09710 ENOG4105BZU Histidine kinase Ami3637_09720 ENOG4108UZE carboxy-peptidase Ami3637_09725 ENOG4105DY9 regulatoR Ami3637_09770 ENOG4108Z5V transcriptional regulator, merr family Ami3637_09775 ENOG4108UQV Membrane Ami3637_09780 ENOG4105KY8 Rubrerythrin Ami3637_09790 ENOG41083MR nifu domain-containing protein Ami3637_09800 ENOG4107QSE Dipeptidase Ami3637_09805 ENOG41081BK membrane protein-like protein Ami3637_09815 ENOG41072GX Peptidase M22 Glycoprotease Ami3637_09820 ENOG410801F ribosomal-protein-alanine acetyltransferase Ami3637_09835 ENOG4105C5H ABC transporter Ami3637_09840 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) Ami3637_09845 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) Ami3637_09865 ENOG4108UQV Membrane Ami3637_09870 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) Ami3637_09875 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) Ami3637_09905 ENOG4108VXD carboxy-peptidase Ami3637_09910 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) Ami3637_09945 ENOG4105T09 s-layer domain-containing protein Ami3637_10000 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) Ami3637_10080 ENOG4108IQI permease Ami3637_10085 ENOG4106P55 Transcriptional regulator Ami3637_10090 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) Ami3637_10100 ENOG4107RCH Diaminopropionate ammonia-lyase Ami3637_10130 ENOG41086D8 Transcriptional regulator Ami3637_10155 ENOG4108REF Sporulation integral membrane protein ytvi Ami3637_10165 ENOG4105KRN Transcriptional regulator, abrb family Ami3637_10180 ENOG4105DDN Pentapeptide repeat-containing protein Ami3637_10200 ENOG4108UIN ybak prolyl-trna synthetase associated region Ami3637_10210 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_10220 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_10225 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) Ami3637_10230 ENOG4108UMI ABC transporter, permease Ami3637_10235 ENOG4105D01 (LipO)protein Ami3637_10255 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) Ami3637_10260 ENOG4108UJD 30S ribosomal protein S9 Ami3637_10265 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) Ami3637_10285 ENOG4108IV0 ABC, transporter Ami3637_10290 ENOG4105C0Z ABC transporter Ami3637_10295 ENOG4105CF8 branched-chain amino acid ABC transporter, permease Ami3637_10300 ENOG4105C32 Amino acid ABC transporter (Permease) Ami3637_10320 ENOG4107XDR Lactoylglutathione lyase Ami3637_10325 ENOG41082CG Protein CrcB homolog Ami3637_10345 ENOG4105E33 succinate dehydrogenase Ami3637_10350 ENOG4108UVJ appr-1-p processing domain protein Ami3637_10375 ENOG4105CD3 dihydroorotase Ami3637_10405 ENOG4107XPA Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) Ami3637_10420 ENOG4105BZ1 (ABC) transporter Ami3637_10430 ENOG4105VKD bioY protein Ami3637_10445 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) Ami3637_10450 ENOG4105C1J atp-dependent rna helicase Ami3637_10455 ENOG4105JVQ RNA Polymerase Ami3637_10460 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) Ami3637_10465 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_10475 ENOG4105CKK Glycosyl transferase, family 2 Ami3637_10490 ENOG4105F8V Hydrolase, tatD family Ami3637_10505 ENOG4105G3A stage ii sporulation protein e Ami3637_10515 ENOG4105C5H ABC transporter Ami3637_10520 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) Ami3637_10525 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) Ami3637_10530 ENOG4108K8K Transcriptional regulator Ami3637_10550 ENOG4105PV1 biotin lipoyl attachment domaiN-containing protein Ami3637_10560 ENOG4105CGM Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity) Ami3637_10565 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) Ami3637_10580 ENOG4105C5S asparaginyl-tRNA synthetase Ami3637_10585 ENOG4105HDK L-asparaginase Ami3637_10595 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) Ami3637_10600 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) Ami3637_10605 ENOG4107R7I amino acid Ami3637_10610 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_10615 ENOG41062D9 Histidine kinase Ami3637_10625 ENOG4105CTP PilT protein domain protein Ami3637_10630 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) Ami3637_10635 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) Ami3637_10640 ENOG4105EN6 Membrane Ami3637_10650 ENOG4107ZE5 PPIases accelerate the folding of proteins Ami3637_10655 ENOG4105FRN stage II sporulation protein Ami3637_10665 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) Ami3637_10675 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) Ami3637_10685 ENOG4105C2N RNA methyltransferase TrmH family group 3 Ami3637_10690 ENOG4105QIV RNA polymerase Ami3637_10705 ENOG4108Z7G MaoC domain protein dehydratase Ami3637_10725 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) Ami3637_10740 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein Ami3637_10770 ENOG410683Z Preprotein translocase SecE subunit Ami3637_10775 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) Ami3637_10780 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) Ami3637_10795 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) Ami3637_10810 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) Ami3637_10815 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) Ami3637_10825 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) Ami3637_10830 ENOG4108RE9 Phosphodiesterase Ami3637_10845 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) Ami3637_10855 ENOG4108JYZ YitT family Ami3637_10860 ENOG4105C4R Atp-dependent dna helicase Ami3637_10895 ENOG4105C6E dna polymerase iii Ami3637_10905 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) Ami3637_10920 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) Ami3637_10925 ENOG4105CJ1 ABC, transporter Ami3637_10955 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) Ami3637_10965 ENOG4105DAP Nicotinate phosphoribosyltransferase Ami3637_10985 ENOG4105D2N Aldolase Ami3637_11010 ENOG4105C3F Signal peptidase i Ami3637_11015 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) Ami3637_11035 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami3637_11060 ENOG4105MCT stage V sporulation protein S Ami3637_11080 ENOG41069ER domain protein Ami3637_11215 ENOG4105PQS phage protein Ami3637_11220 ENOG4105FR7 XkdM protein, phage-like element PBSX Ami3637_11255 ENOG41066EA baseplate J family protein Ami3637_11330 ENOG4105EA8 2-Nitropropane dioxygenase Ami3637_11340 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Ami3637_11350 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase Ami3637_11355 ENOG4105K56 Transcriptional regulator Ami3637_11415 ENOG4108RNG Permease of the drug metabolite transporter Ami3637_11420 ENOG4105KVH Transcriptional regulator Ami3637_11465 ENOG4107XVH Transcriptional regulator Ami3637_11475 ENOG4105CV8 reductase Ami3637_11480 ENOG4106HBX Transcriptional Regulator AraC Family Ami3637_11485 ENOG4108Q52 Methyltransferase cognate corrinoid protein Ami3637_11510 ENOG4108Q52 Methyltransferase cognate corrinoid protein Ami3637_11535 ENOG4107QSQ Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) Ami3637_11555 ENOG4105CKI cobalamin synthesis protein Ami3637_11575 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_11595 ENOG4105CDW Resistance protein Ami3637_11605 ENOG4106TD9 Diguanylate cyclase Ami3637_11625 ENOG4105CW7 secretion protein, HlyD family Ami3637_11655 ENOG4105BZU Histidine kinase Ami3637_11660 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami3637_11665 ENOG4105CUB amino acid Ami3637_11670 ENOG4105CUB amino acid Ami3637_11675 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) Ami3637_11680 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) Ami3637_11685 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein Ami3637_11695 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD Ami3637_11715 ENOG4105C2J ABC transporter Ami3637_11730 ENOG4105CPQ Dehydrogenase Ami3637_11735 ENOG4105CMG Carbohydrate kinase Ami3637_11740 ENOG4105ETE Transcriptional regulator (LacI family Ami3637_11750 ENOG4105C2J ABC transporter Ami3637_11755 ENOG4105CNN ABC, transporter Ami3637_11760 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator Ami3637_11765 ENOG4105D7W serine acetyltransferase Ami3637_11770 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_11780 ENOG4105C5W Aldolase Ami3637_11785 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) Ami3637_11805 ENOG4105MT0 Sporulation transcriptional regulator spoiiid Ami3637_11835 ENOG410624X efflux transporter, rnd family, mfp subunit Ami3637_11845 ENOG4105C19 ABC transporter Ami3637_11850 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) Ami3637_11855 ENOG4107RBB ABC transporter, permease Ami3637_11895 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) Ami3637_11900 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic Ami3637_11905 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain Ami3637_11910 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain Ami3637_11915 ENOG4108NEV two component transcriptional regulator, LytTR family Ami3637_11940 ENOG4106V2I dimethylaminohydrolase Ami3637_11945 ENOG4108WYP Transcriptional regulator Ami3637_11950 ENOG4105C02 permease Ami3637_11985 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) Ami3637_11995 ENOG4105FA2 dna polymerase iii Ami3637_12005 ENOG41060K3 Methyltransferase Ami3637_12040 ENOG4105C3G gtp-binding protein Ami3637_12045 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) Ami3637_12050 ENOG4105CUZ uba thif-type nad fad binding protein Ami3637_12055 ENOG4105SYT Methylenetetrahydrofolate reductase Ami3637_12065 ENOG4108V6E Cell division protein mraZ Ami3637_12080 ENOG4107RVG penicillin-binding protein Ami3637_12090 ENOG4105CJN penicillin-binding protein Ami3637_12095 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) Ami3637_12100 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) Ami3637_12105 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) Ami3637_12110 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) Ami3637_12120 ENOG4105CNI cell division protein FtsW Ami3637_12125 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) Ami3637_12130 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) Ami3637_12150 ENOG4105K67 small basic protein Ami3637_12155 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) Ami3637_12160 ENOG4105C2N RNA methyltransferase TrmH family group 3 Ami3637_12165 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) Ami3637_12170 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) Ami3637_12175 ENOG410687F Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) Ami3637_12190 ENOG4105C75 arginyL-tRNA synthetase Ami3637_12265 ENOG4105DZR Type I site-specific deoxyribonuclease Ami3637_12285 ENOG4108NF7 phage-type endonuclease Ami3637_12395 ENOG4105E0Y RtcB Protein Ami3637_12400 ENOG410756H nucleotidyltransferase Ami3637_12405 ENOG4107YDN peptide deformylase Ami3637_12410 ENOG4105D3R alkyl hydroperoxide reductase Ami3637_12420 ENOG4105C1B dTDP-glucose 4-6-dehydratase Ami3637_12425 ENOG4107QQG Dehydrogenase Ami3637_12450 ENOG4105BZU Histidine kinase Ami3637_12460 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_12515 ENOG4105C5H ABC transporter Ami3637_12520 ENOG4105CFP Peptidase U32 Ami3637_12530 ENOG4108IQI permease Ami3637_12535 ENOG4105EAY pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Ami3637_12540 ENOG4105M3W utilization protein Ami3637_12545 ENOG4105KTW ethanolamine utilization protein Ami3637_12550 ENOG4105CSX c4-dicarboxylate anaerobic carrier Ami3637_12560 ENOG4105C0B DNA polymerase III (alpha subunit) Ami3637_12565 ENOG4105CTQ phosphohexokinase Ami3637_12570 ENOG41061ZR Transcriptional regulator Ami3637_12575 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase Ami3637_12585 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Ami3637_12590 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) Ami3637_12595 ENOG4105ECC imidazole-glycerol-phosphate dehydratase Ami3637_12600 ENOG4105CIH Imidazole acetol-phosphate transaminase Ami3637_12605 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) Ami3637_12610 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) Ami3637_12615 ENOG4108IQ6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) Ami3637_12625 ENOG4105DRR Transcriptional regulator, GntR family Ami3637_12630 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) Ami3637_12635 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) Ami3637_12640 ENOG4105CSM endonuclease III Ami3637_12660 ENOG41082JN Transcriptional regulator Ami3637_12665 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving Ami3637_12670 ENOG4105D6E homoserine dehydrogenase Ami3637_12680 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami3637_12695 ENOG4105CP7 Triose-phosphate isomerase Ami3637_12700 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) Ami3637_12705 ENOG4105XZU Preprotein translocase, subunit SecG Ami3637_12740 ENOG4105CM2 brancheD-chain amino acid aminotransferase Ami3637_12760 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) Ami3637_12765 ENOG41080XP Cbs domain Ami3637_12770 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) Ami3637_12775 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) Ami3637_12790 ENOG410667J hydrolase Ami3637_12800 ENOG4105VFF UPF0102 protein Ami3637_12810 ENOG4105C79 DNA protecting protein DprA Ami3637_12820 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) Ami3637_12825 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) Ami3637_12830 ENOG4105EUM DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity) Ami3637_12840 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) Ami3637_12845 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein Ami3637_12990 ENOG4107104 thymidine kinase Ami3637_12995 ENOG4105N5T Radical SAM Protein Ami3637_13005 ENOG4105C25 Primosomal protein n' Ami3637_13010 ENOG4105C25 Primosomal protein n' Ami3637_13015 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) Ami3637_13030 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B Ami3637_13040 ENOG4105D9P serine threonine protein kinase Ami3637_13045 ENOG4105D9P serine threonine protein kinase Ami3637_13050 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) Ami3637_13055 ENOG4105DJV ribulose-phosphate 3-epimerase Ami3637_13060 ENOG4105EHR propanediol utilization protein pduB Ami3637_13065 ENOG4105C5H ABC transporter Ami3637_13140 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Ami3637_13145 ENOG4105CBX hi0933 family Ami3637_13155 ENOG4105CXN decarboxylase Ami3637_13165 ENOG4105DVE abc transporter atp-binding protein Ami3637_13170 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family Ami3637_13175 ENOG4105CU9 asparagine synthetase A Ami3637_13180 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase Ami3637_13185 ENOG4105D07 Signal peptide peptidase, SppA Ami3637_13190 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) Ami3637_13205 ENOG4105VB6 UPF0109 protein Ami3637_13210 ENOG4107Z8R An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) Ami3637_13225 ENOG4105DFA alanine racemase domain protein Ami3637_13230 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) Ami3637_13240 ENOG4107VQS DivIVA family Ami3637_13245 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) Ami3637_13250 ENOG4105C34 Pseudouridine synthase Ami3637_13270 ENOG4105DSJ YicC domain protein Ami3637_13275 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) Ami3637_13290 ENOG4105CE9 30S ribosomal protein S2 Ami3637_13305 ENOG4105DHT Metal Dependent Phosphohydrolase Ami3637_13315 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) Ami3637_13320 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) Ami3637_13335 ENOG4105DZP Membrane-associated zinc metalloprotease Ami3637_13340 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) Ami3637_13355 ENOG4105DZS Phenylacetate-CoA ligase Ami3637_13365 ENOG4105DZS Phenylacetate-CoA ligase Ami3637_13375 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) Ami3637_13380 ENOG4105CHV Transcription elongation factor NusA Ami3637_13395 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) Ami3637_13400 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) Ami3637_13405 ENOG4105SFS phosphoesterase RecJ domain protein Ami3637_13420 ENOG4105DTN riboflavin biosynthesis protein ribF Ami3637_13425 ENOG4105BZU Histidine kinase Ami3637_13430 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) Ami3637_13445 ENOG4105WH1 Two component transcriptional regulator luxr family Ami3637_13450 ENOG4105BZU Histidine kinase Ami3637_13465 ENOG4105E0M Sulfatase Ami3637_13480 ENOG4107S8T NAD-dependent 4-hydroxybutyrate dehydrogenase Ami3637_13490 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) Ami3637_13495 ENOG4108R6K riboflavin synthase, subunit alpha Ami3637_13500 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) Ami3637_13540 ENOG4105CG9 aspartate racemase Ami3637_13545 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) Ami3637_13550 ENOG4105F4P )-transporter Ami3637_13565 ENOG4105CPF Cell wall formation (By similarity) Ami3637_13595 ENOG4105BZG amino acid carrier protein Ami3637_13610 ENOG4108IQI permease Ami3637_13660 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase Ami3637_13670 ENOG4105DWU Membrane Ami3637_13675 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) Ami3637_13685 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) Ami3637_13690 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) Ami3637_13695 ENOG4105VJV 50s ribosomal protein L35 Ami3637_13710 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami3637_13735 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) Ami3637_13745 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) Ami3637_13750 ENOG4105C9M aspartyl-trna synthetase Ami3637_13765 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation Ami3637_13770 ENOG4105WR5 sporulation protein, YlmC YmxH family Ami3637_13775 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) Ami3637_13780 ENOG4105CAT Cytidine monophosphate kinase Ami3637_13805 ENOG4105CUB amino acid Ami3637_13810 ENOG4108HGU Histidine kinase Ami3637_13820 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami3637_13845 ENOG4108KHX Diguanylate cyclase Ami3637_13865 ENOG4107Y5K Resolvase Ami3637_13875 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami3637_13885 ENOG4105W5Q DNA repair protein (RadC Ami3637_13890 ENOG4105DFF Rod shape-determining protein mreb Ami3637_13905 ENOG4107RF6 penicillin-binding protein Ami3637_13910 ENOG4107QMS site-determining protein Ami3637_13915 ENOG4105CNI cell division protein FtsW Ami3637_13925 ENOG4107QI1 Mate efflux family protein Ami3637_13930 ENOG4107QI6 Cysteine desulfurase Ami3637_13935 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) Ami3637_13940 ENOG41082AN stage II sporulation protein Ami3637_13945 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) Ami3637_13950 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami3637_13955 ENOG4105C1G acyl-Coa dehydrogenase Ami3637_13960 ENOG4105BZJ Electron transfer flavoprotein Ami3637_13965 ENOG4105C10 Electron transfer flavoprotein Ami3637_13980 ENOG41090VF Stage v sporulation protein ac Ami3637_13985 ENOG4105CZ3 stage V sporulation protein ad Ami3637_14015 ENOG4105BZ4 penicillin-binding protein Ami3637_14030 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 Ami3637_14050 ENOG410902H NADH dehydrogenase (Ubiquinone), 24 kDa subunit Ami3637_14075 ENOG4108ZUB Lysine exporter protein (Lyse ygga) Ami3637_14105 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_14110 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) Ami3637_14115 ENOG4108WUH Transcriptional regulator, TetR family Ami3637_14120 ENOG4105E39 Enoyl-CoA hydratase Ami3637_14140 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) Ami3637_14160 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) Ami3637_14180 ENOG4105C08 Histidine kinase Ami3637_14185 ENOG4105EEX Two component transcriptional regulator (Winged helix family Ami3637_14195 ENOG4107ZYR domain protein Ami3637_14205 ENOG4105DZ1 carboxypeptidase Ami3637_14215 ENOG4105PW4 Sugar fermentation stimulation protein homolog Ami3637_14260 ENOG4105MJ6 selenium-dependent hydroxylase accessory protein YqeC Ami3637_14275 ENOG4105EJ5 oxidoreductase gamma subunit Ami3637_14285 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) Ami3637_14290 ENOG4105DDK oxidoreductase, beta subunit Ami3637_14310 ENOG4107V2S Transcriptional regulator Ami3637_14345 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) Ami3637_14360 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase Ami3637_14370 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 Ami3637_14375 ENOG4105DWF phosphomethylpyrimidine kinase Ami3637_14380 ENOG4108QBV Monogalactosyldiacylglycerol synthase Ami3637_14395 ENOG4105D3A purine nucleoside phosphorylase DeoD-type Ami3637_14405 ENOG4105CEY Amp-dependent synthetase and ligase Ami3637_14425 ENOG4105FDS Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) Ami3637_14435 ENOG4105CJG carbon-monoxide dehydrogenase catalytic subunit Ami3637_14445 ENOG4108IFG nitrite reductase, (NAD(P)H) Ami3637_14450 ENOG4108UT2 hemolysin iii Ami3637_14455 ENOG4105BZU Histidine kinase Ami3637_14465 ENOG4108UIC UPF0340 protein Ami3637_14475 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family Ami3637_14485 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_14490 ENOG4108IUW ABC transporter Ami3637_14510 ENOG4108Z5V transcriptional regulator, merr family Ami3637_14515 ENOG4108R96 Methyltransferase, YaeB family Ami3637_14525 ENOG4105WEF catalase Ami3637_14535 ENOG41080S5 HTH_DTXR Ami3637_14545 ENOG4105CE1 Ferrous iron transport protein b Ami3637_14565 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_14590 ENOG4105VZ8 Transcriptional regulator Ami3637_14600 ENOG4105C0X amino acid Ami3637_14615 ENOG41084T3 4fe-4S ferredoxin iron-sulfur binding domain-containing protein Ami3637_14755 ENOG4105G9B Transcriptional regulator Ami3637_14770 ENOG4108K8K Transcriptional regulator Ami3637_14775 ENOG4105CIH Imidazole acetol-phosphate transaminase Ami3637_14830 ENOG4107QYX exodeoxyribonuclease v alpha Ami3637_14910 ENOG4108ZQX ybak prolyl-trna synthetase Ami3637_14915 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) Ami3637_14930 ENOG41080VW acetyltransferase Ami3637_14945 ENOG4105DIN metallophosphoesterase Ami3637_14975 ENOG410810Y Sulfite reductase Ami3637_14980 ENOG4107SHJ sulfite reductase subunit b Ami3637_14985 ENOG4105D5B Sulfite reductase, subunit A Ami3637_14995 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) Ami3637_15030 ENOG4108Z7F N-acetyltransferase Ami3637_15055 ENOG4107RWR Sodium hydrogen exchanger Ami3637_15080 ENOG4108W2W Ami3637_15085 ENOG4105C0X amino acid Ami3637_15090 ENOG4105DZ1 carboxypeptidase Ami3637_15095 ENOG4105JVQ RNA Polymerase Ami3637_15100 ENOG4108P49 AntiSigma factor Ami3637_15110 ENOG4105KPY Small multidrug resistance protein Ami3637_15130 ENOG4105E4X binding-protein-dependent transport systems inner membrane Component Ami3637_15140 ENOG4105S9S Binding-protein-dependent transport systems, inner membrane component Ami3637_15195 ENOG4107XCH Cyclase family Ami3637_15220 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component Ami3637_15225 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) Ami3637_15235 ENOG4107RSS Hydrogenase accessory protein HypB Ami3637_15240 ENOG4105KVH Transcriptional regulator Ami3637_15250 ENOG4108R3D Electron transport complex Ami3637_15260 ENOG4105F3H Histidine kinase Ami3637_15265 ENOG4105CK6 Two component transcriptional regulator (Winged helix family Ami3637_15280 ENOG4105GXZ Ferredoxin-type protein NapH Ami3637_15295 ENOG4107R11 Transcriptional regulator Ami3637_15305 ENOG4108ZJ4 polysaccharide deacetylase Ami3637_15310 ENOG4105EPI acetyltransferase, (GNAT) family Ami3637_15315 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen Ami3637_15325 ENOG4105G7B Protein of unknown function (DUF2992) Ami3637_15335 ENOG4105F32 YngK protein Ami3637_15350 ENOG4107RFY SbcCD D subunit Ami3637_15355 ENOG4105EYH Exonuclease Ami3637_15365 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin Ami3637_15370 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_15410 ENOG4105MZU cell filamentation protein Ami3637_15420 ENOG4105DFM M18 family aminopeptidase Ami3637_15425 ENOG4105DC7 peptidase M24 Ami3637_15445 ENOG4105K4H Nlp p60 protein Ami3637_15450 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division Ami3637_15470 ENOG4105BZ1 (ABC) transporter Ami3637_15485 ENOG41061ZR Transcriptional regulator Ami3637_15510 ENOG4105C87 Aminotransferase class I and II Ami3637_15525 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_15535 ENOG4108MCP Propeptide_C25 Ami3637_15540 ENOG4108IQI permease Ami3637_15545 ENOG4105BZU Histidine kinase Ami3637_15550 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family Ami3637_15560 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_15605 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami3637_15645 ENOG4108YYH Nadph-dependent fmn reductase Ami3637_15675 ENOG4105BZU Histidine kinase Ami3637_15680 ENOG4105BZU Histidine kinase Ami3637_15685 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase Ami3637_15690 ENOG4105KAV tspo and mbr like protein Ami3637_15730 ENOG4105EVY Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity) Ami3637_15750 ENOG4105E4P ATPase (AAA Ami3637_15765 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein Ami3637_15785 ENOG4105C1V Peptidase, M16 Ami3637_15795 ENOG4108P62 biosynthesis protein (CbiG) Ami3637_15800 ENOG4105CX4 Precorrin-6y C5,15-methyltransferase Ami3637_15805 ENOG4105C0Y Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) Ami3637_15815 ENOG4105CIA precorrin-4 C(11)-methyltransferase Ami3637_15820 ENOG4105E4R Precorrin-3B C17-methyltransferase Ami3637_15830 ENOG4107QZB decarboxylase Ami3637_15840 ENOG41081F0 Precorrin-8x methylmutase Ami3637_15845 ENOG4105CH6 catalase Ami3637_15860 ENOG4105CJ3 phosphate transporter Ami3637_15865 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein Ami3637_15870 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) Ami3637_15880 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) Ami3637_15885 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) Ami3637_15925 ENOG4105CDY transcriptional regulatory protein Ami3637_15940 ENOG4105TMB Formate nitrite transporter Ami3637_15955 ENOG4105KXX peptidase s58 dmpa Ami3637_15965 ENOG4105C37 (CBS) domain Ami3637_15970 ENOG4107RVV histidinol phosphate phosphatase, hisj family Ami3637_15975 ENOG4105EMN RNA polymerase sigma factor Ami3637_15985 ENOG4105C2M dna polymerase I Ami3637_15990 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) Ami3637_16010 ENOG4105VIE preprotein translocase, subunit YajC Ami3637_16020 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) Ami3637_16025 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) Ami3637_16030 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) Ami3637_16035 ENOG4105C5X domain protein Ami3637_16040 ENOG4105D4P Coproporphyrinogen iii oxidase Ami3637_16045 ENOG4105CUT histidyl-tRNA synthetase Ami3637_16050 ENOG4105C9M aspartyl-trna synthetase Ami3637_16060 ENOG4108WF2 Metal Dependent Phosphohydrolase Ami3637_16075 ENOG4105CN5 Metallo-Beta-Lactamase Ami3637_16080 ENOG41084CE UPF0342 protein Ami3637_16085 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) Ami3637_16090 ENOG4105HHA aminodeoxychorismate lyase Ami3637_16100 ENOG4105CFP Peptidase U32 Ami3637_16115 ENOG4105CD2 stage iii sporulation protein aa Ami3637_16130 ENOG4105KQ4 Stage iii sporulation protein ad Ami3637_16135 ENOG4105CPC Aldo Keto reductase Ami3637_16145 ENOG4105VBH UPF0297 protein Ami3637_16150 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) Ami3637_16165 ENOG4105VUF Transcriptional regulator Ami3637_16175 ENOG4105CPC Aldo Keto reductase Ami3637_16180 ENOG4105KME endoribonuclease L-psp Ami3637_16190 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) Ami3637_16210 ENOG4108RAC Rubrerythrin Ami3637_16255 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) Ami3637_16280 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase Ami3637_16285 ENOG4108N5C SNARE associated Golgi protein-related protein Ami3637_16290 ENOG4105CXI aluminum resistance protein Ami3637_16295 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami3637_16300 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) Ami3637_16305 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) Ami3637_16310 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) Ami3637_16315 ENOG4105CHM Aminotransferase Ami3637_16345 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) Ami3637_16350 ENOG4105M7K Involved in the transcription termination process (By similarity) Ami3637_16380 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins Ami3637_16395 ENOG41086WU UPF0291 protein Ami3637_16405 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase Ami3637_16410 ENOG4107QQR Sporulation Ami3637_16415 ENOG4105S1Z Stage IV sporulation protein B Ami3637_16425 ENOG4105KQC Competence protein Ami3637_16435 ENOG4105CSA Coproporphyrinogen iii oxidase Ami3637_16460 ENOG4105K46 50S ribosomal protein l27 Ami3637_16465 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) Ami3637_16470 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) Ami3637_16480 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase Ami3637_16485 ENOG4105CBM Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity) Ami3637_16560 ENOG4108WZM domain protein Ami3637_16640 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) Ami3637_16705 ENOG4108UUM single-stranded DNA-binding protein Ami3637_16715 ENOG4107QJE Chromosome Partitioning Protein Ami3637_16785 ENOG41067VY 50S ribosomal protein L32 Ami3637_16790 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) Ami3637_16810 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) Ami3637_16815 ENOG4106H78 methyltransferase Ami3637_16825 ENOG4105CB5 ATP-dependent DNA helicase recG Ami3637_16835 ENOG4105VB9 50S ribosomal protein l28 Ami3637_16840 ENOG4105F1A Pyruvate formate-lyase Ami3637_16845 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase Ami3637_16865 ENOG4105DUM transcriptional regulator, lysR family Ami3637_16870 ENOG4105HMI Membrane Ami3637_16880 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_16885 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_16890 ENOG4105C8Q Methyl-accepting chemotaxis Ami3637_16895 ENOG4108RZE Tetr family transcriptional regulator Ami3637_16900 ENOG4105CEN a g-specific adenine glycosylase Ami3637_16920 ENOG4108RIR Molybdenum cofactor biosynthesis protein Ami3637_16930 ENOG4105BZU Histidine kinase Ami3637_16965 ENOG4107QN2 dihydrolipoyl dehydrogenase Ami3637_16980 ENOG41087YS Phage shock protein A Ami3637_16985 ENOG4105HIR S-layer domain protein