locus-tag	class	description
CO731_00001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CO731_00002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CO731_00003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CO731_00008	ENOG4105C5I	Dehydrogenase
CO731_00010	ENOG4105G5W	regulator Fur family
CO731_00011	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CO731_00013	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CO731_00014	ENOG4105BZU	Histidine kinase
CO731_00015	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CO731_00016	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CO731_00017	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CO731_00018	ENOG4105D7N	magnesium and cobalt transport protein CorA
CO731_00019	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CO731_00020	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CO731_00021	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CO731_00024	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CO731_00030	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CO731_00031	ENOG4105DHQ	Histidine kinase
CO731_00032	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CO731_00033	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CO731_00034	ENOG4108WRK	Transcriptional regulator
CO731_00035	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CO731_00036	ENOG4107RCQ	(CBS) domain
CO731_00037	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CO731_00038	ENOG4105C9A	Phoh family
CO731_00039	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CO731_00040	ENOG4108JBU	Outer membrane protein Omp31
CO731_00045	ENOG41072GX	Peptidase M22 Glycoprotease
CO731_00046	ENOG4107QP3	malate synthase g
CO731_00053	ENOG4105VC4	domain protein
CO731_00054	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CO731_00063	ENOG4105VC4	domain protein
CO731_00067	ENOG410841Q	phosphoesterase PA-phosphatase related protein
CO731_00069	ENOG4105CHH	sulfate transporter
CO731_00070	ENOG4105R8A	Heat shock protein
CO731_00071	ENOG4108NIW	Leucine export protein LeuE
CO731_00074	ENOG4105GRZ	Ycii-related protein
CO731_00081	ENOG4108ZHR	arsR family transcriptional regulator
CO731_00083	ENOG4108K3A	Glutathione S-transferase
CO731_00087	ENOG4107QWP	ABC-2 type transporter
CO731_00088	ENOG4105CJ1	ABC, transporter
CO731_00091	ENOG41080ZE	Adenylate cyclase
CO731_00096	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
CO731_00097	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CO731_00099	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CO731_00100	ENOG4105CSA	Coproporphyrinogen iii oxidase
CO731_00103	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CO731_00104	ENOG41082FP	UPF0102 protein
CO731_00107	ENOG4106IPI	cyclase, family
CO731_00111	ENOG410903D	sensor protein
CO731_00112	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CO731_00114	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CO731_00117	ENOG4105C08	Histidine kinase
CO731_00118	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CO731_00119	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CO731_00120	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CO731_00122	ENOG4108K3A	Glutathione S-transferase
CO731_00123	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CO731_00126	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CO731_00127	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CO731_00128	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CO731_00129	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CO731_00133	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CO731_00138	ENOG4108JQ9	ABC transporter
CO731_00139	ENOG4105ZDB	Protein slyX homolog
CO731_00141	ENOG4105DIH	basic membrane
CO731_00142	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CO731_00147	ENOG4105GZI	Transcriptional regulator
CO731_00148	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CO731_00150	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CO731_00151	ENOG4105CXK	mandelate racemase muconate lactonizing
CO731_00153	ENOG4108JQ5	ABC transporter
CO731_00154	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_00155	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_00156	ENOG4108J59	Extracellular solute-binding protein, family 5
CO731_00158	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CO731_00159	ENOG4105CH2	amidohydrolase
CO731_00160	ENOG4108J59	Extracellular solute-binding protein, family 5
CO731_00162	ENOG4105CSW	GntR family transcriptional regulator
CO731_00165	ENOG4108KQ5	Integrase catalytic subunit
CO731_00168	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CO731_00171	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CO731_00172	ENOG4105DEI	Mannitol dehydrogenase
CO731_00173	ENOG4105CHR	reductase
CO731_00174	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_00179	ENOG4108UKZ	OsmC family
CO731_00180	ENOG4105CYN	Serine protein kinase
CO731_00182	ENOG4105ED1	spovr family
CO731_00183	ENOG4106N3A	copper homeostasis protein cutc
CO731_00184	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CO731_00185	ENOG4105ETE	Transcriptional regulator (LacI family
CO731_00186	ENOG4106PMH	Extracellular solute-binding protein family 3
CO731_00189	ENOG4105E5Q	amino acid AbC transporter
CO731_00190	ENOG4105E5Q	amino acid AbC transporter
CO731_00196	ENOG4108JJA	ABC, transporter
CO731_00197	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CO731_00204	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CO731_00205	ENOG4108RVA	ribokinase
CO731_00206	ENOG410829K	Lysine exporter protein (Lyse ygga)
CO731_00207	ENOG4105DU0	nucleoside hydrolase
CO731_00208	ENOG4108ZNX	Heat shock protein
CO731_00210	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CO731_00211	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
CO731_00212	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CO731_00213	ENOG4108IUZ	ABC transporter
CO731_00214	ENOG4105RF0	OstA family
CO731_00216	ENOG4105D07	Signal peptide peptidase, SppA
CO731_00217	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CO731_00219	ENOG4105CIF	Ornithine Cyclodeaminase
CO731_00220	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CO731_00222	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CO731_00224	ENOG4105BZU	Histidine kinase
CO731_00228	ENOG4105CEP	NADH dehydrogenase
CO731_00229	ENOG4105EN6	Membrane
CO731_00230	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CO731_00233	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CO731_00234	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CO731_00236	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CO731_00238	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CO731_00240	ENOG41082F9	transcriptional regulator
CO731_00242	ENOG4108JQC	penicillin-binding protein 1A
CO731_00249	ENOG4107U9H	DNA polymerase
CO731_00251	ENOG4105C2M	dna polymerase I
CO731_00254	ENOG4105CPC	Aldo Keto reductase
CO731_00255	ENOG4105CK5	oxidoreductase
CO731_00258	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CO731_00260	ENOG4105FKQ	transcriptional regulator
CO731_00261	ENOG4105EPJ	extracellular solute-binding protein family 1
CO731_00262	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
CO731_00263	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
CO731_00264	ENOG4105CG3	alpha amylase, catalytic region
CO731_00265	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_00266	ENOG4105CC5	ABC transporter
CO731_00267	ENOG4105CC5	ABC transporter
CO731_00268	ENOG4105DIK	(ABC) transporter
CO731_00269	ENOG4105DSE	periplasmic solute binding protein
CO731_00274	ENOG4105EMN	RNA polymerase sigma factor
CO731_00275	ENOG4108JQ7	(ABC) transporter
CO731_00276	ENOG4105C3U	ABC transporter
CO731_00277	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_00279	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_00280	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
CO731_00281	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CO731_00298	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CO731_00300	ENOG4105C3U	ABC transporter
CO731_00301	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_00305	ENOG4107Y80	Major Facilitator superfamily
CO731_00311	ENOG4107Y80	Major Facilitator superfamily
CO731_00313	ENOG41061MD	high-affinity nickel-transporter
CO731_00319	ENOG4105GZI	Transcriptional regulator
CO731_00321	ENOG4105M4H	endoribonuclease L-psp
CO731_00326	ENOG4105RQF	LysR family Transcriptional regulator
CO731_00327	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_00331	ENOG4108KQ5	Integrase catalytic subunit
CO731_00342	ENOG4105E5Q	amino acid AbC transporter
CO731_00344	ENOG4105CDA	abc transporter atp-binding protein
CO731_00347	ENOG4105E1J	oxidoreductase
CO731_00348	ENOG4108KB2	LysR family Transcriptional regulator
CO731_00350	ENOG41061MD	high-affinity nickel-transporter
CO731_00354	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CO731_00363	ENOG4105C3U	ABC transporter
CO731_00364	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_00365	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_00371	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
CO731_00400	ENOG4105K70	DNA-binding protein
CO731_00413	ENOG4107Z1W	Fructose transport system kinase
CO731_00415	ENOG4105CYM	Glutathione S-transferase
CO731_00418	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CO731_00419	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CO731_00420	ENOG4105XDF	Protein of unknown function (DUF1272)
CO731_00421	ENOG4105KI2	Urea amidohydrolase subunit beta
CO731_00425	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CO731_00426	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CO731_00428	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CO731_00430	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CO731_00432	ENOG4105ETT	transcriptional Regulator, LysR family
CO731_00433	ENOG4107QI1	Mate efflux family protein
CO731_00435	ENOG4105F38	ABC transporter, permease
CO731_00436	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_00438	ENOG4105E5Q	amino acid AbC transporter
CO731_00439	ENOG4105E5Q	amino acid AbC transporter
CO731_00440	ENOG4105F87	Dehydratase
CO731_00441	ENOG4105CYW	agmatinase
CO731_00442	ENOG4105ETT	transcriptional Regulator, LysR family
CO731_00443	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CO731_00446	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_00448	ENOG4108IJ6	ABC transporter
CO731_00449	ENOG4108IV0	ABC, transporter
CO731_00451	ENOG4108RWI	nicotinamidase
CO731_00453	ENOG4105C7W	Xanthine dehydrogenase
CO731_00457	ENOG4108VHT	MarR family transcriptional regulator
CO731_00458	ENOG4105C26	Dehydrogenase
CO731_00459	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CO731_00460	ENOG4105DP0	ferredoxin-NADP reductase
CO731_00463	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_00465	ENOG4105DRS	transport system, permease
CO731_00466	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CO731_00468	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CO731_00469	ENOG4105RD7	BadF BadG BcrA BcrD
CO731_00470	ENOG4105FDP	GntR family transcriptional regulator
CO731_00472	ENOG4105CE4	GlcNAc 6-P deacetylase
CO731_00473	ENOG4105DJV	ribulose-phosphate 3-epimerase
CO731_00476	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CO731_00478	ENOG4105CNN	ABC, transporter
CO731_00479	ENOG4105CNN	ABC, transporter
CO731_00480	ENOG4105ETE	Transcriptional regulator (LacI family
CO731_00482	ENOG4108RVA	ribokinase
CO731_00484	ENOG4105CHP	RNA polymerase
CO731_00485	ENOG4105GRZ	Ycii-related protein
CO731_00486	ENOG4108JPW	Aminotransferase
CO731_00494	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
CO731_00495	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CO731_00496	ENOG4105F1N	DNA alkylation repair
CO731_00503	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CO731_00504	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
CO731_00505	ENOG4105CR4	methylisocitrate lyase
CO731_00510	ENOG4105C6K	Malic enzyme
CO731_00511	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CO731_00521	ENOG4105CIR	epoxide hydrolase
CO731_00522	ENOG4105FTV	AraC Family Transcriptional Regulator
CO731_00524	ENOG4108RZE	Tetr family transcriptional regulator
CO731_00528	ENOG4105BZU	Histidine kinase
CO731_00530	ENOG4105CV8	reductase
CO731_00533	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CO731_00534	ENOG4105CJR	Integral membrane protein (MviN
CO731_00535	ENOG4105C31	Tryptophanyl-tRNA synthetase
CO731_00537	ENOG41083MR	nifu domain-containing protein
CO731_00538	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CO731_00540	ENOG4108UYB	regulatoR
CO731_00541	ENOG4105TX3	Histidine kinase
CO731_00542	ENOG4105CQ7	ATP-dependent helicase
CO731_00548	ENOG4106G6Q	Transcriptional regulator
CO731_00549	ENOG4105C01	Dihydroxy-acid dehydratase
CO731_00551	ENOG4105C28	cystathionine
CO731_00552	ENOG4108ZT1	Transcriptional regulator
CO731_00553	ENOG4108KTG	Membrane protein, drug metabolite transporter
CO731_00554	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CO731_00555	ENOG4108IY8	ABC, transporter
CO731_00556	ENOG4106FTQ	Taurine ABC transporter, periplasmic
CO731_00558	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CO731_00559	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CO731_00561	ENOG4108IUZ	ABC transporter
CO731_00562	ENOG4105C0Z	ABC transporter
CO731_00563	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_00565	ENOG4105CAD	extracellular ligand-binding receptor
CO731_00566	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
CO731_00567	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
CO731_00568	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
CO731_00569	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
CO731_00570	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
CO731_00571	ENOG4105F2Z	3-oxoadipate enol-lactonase
CO731_00572	ENOG4105DDW	LysR family Transcriptional regulator
CO731_00573	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
CO731_00575	ENOG4108WYP	Transcriptional regulator
CO731_00576	ENOG4105D5U	fad dependent oxidoreductase
CO731_00579	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CO731_00580	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CO731_00582	ENOG4105E4C	Lytic transglycosylase catalytic
CO731_00587	ENOG4108JQ1	Dehydrogenase
CO731_00589	ENOG4107S2N	Type III effector Hrp-dependent
CO731_00590	ENOG4108JQ7	(ABC) transporter
CO731_00592	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_00593	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_00594	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_00596	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CO731_00598	ENOG4105C0A	alcohol dehydrogenase
CO731_00600	ENOG4108IV0	ABC, transporter
CO731_00603	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_00604	ENOG4105C0Z	ABC transporter
CO731_00605	ENOG4108IQE	Amp-dependent synthetase and ligase
CO731_00607	ENOG4108ZCF	integral membrane protein
CO731_00619	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CO731_00620	ENOG4105CPQ	Dehydrogenase
CO731_00622	ENOG4108JQ7	(ABC) transporter
CO731_00624	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_00625	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_00628	ENOG4108QBF	Transcriptional regulator
CO731_00631	ENOG4107QP3	malate synthase g
CO731_00632	ENOG4105FBA	Phospholipase Carboxylesterase
CO731_00633	ENOG4107Z7P	Ferredoxin
CO731_00634	ENOG4106A3M	Cytochrome p-450
CO731_00637	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CO731_00640	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CO731_00643	ENOG4108ZZF	transport protein (ExbD)
CO731_00650	ENOG4105DUU	IucA IucC family protein
CO731_00651	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_00653	ENOG4108WBH	protein TIM barrel
CO731_00655	ENOG4105DHS	permease protein
CO731_00656	ENOG4105CM4	permease protein
CO731_00657	ENOG4108IPW	abc transporter atp-binding protein
CO731_00659	ENOG4105F2Z	3-oxoadipate enol-lactonase
CO731_00660	ENOG4108IV0	ABC, transporter
CO731_00661	ENOG4105C0Z	ABC transporter
CO731_00663	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_00666	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
CO731_00669	ENOG4105FUY	alpha subunit
CO731_00674	ENOG4108A65	Transcriptional regulator
CO731_00675	ENOG4105D6J	arsenicaL-resistance protein
CO731_00677	ENOG4105CAU	Arsenical resistance protein, ArsH
CO731_00695	ENOG4105CEC	DNA methylase N-4 N-6
CO731_00699	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CO731_00701	ENOG4105F04	LysR family Transcriptional regulator
CO731_00708	ENOG4105DQ6	Transposase
CO731_00714	ENOG4105DC7	peptidase M24
CO731_00716	ENOG4105C2J	ABC transporter
CO731_00717	ENOG4105CNN	ABC, transporter
CO731_00722	ENOG4105E5H	Transposase
CO731_00724	ENOG4108MVM	Transposase
CO731_00726	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_00729	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
CO731_00734	ENOG4105EQR	Transposase IS116 IS110 IS902
CO731_00738	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_00740	ENOG4105F38	ABC transporter, permease
CO731_00750	ENOG4105EVZ	LysR family transcriptional regulator
CO731_00752	ENOG4108PZW	LysR family Transcriptional regulator
CO731_00758	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CO731_00759	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_00761	ENOG4105F38	ABC transporter, permease
CO731_00769	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CO731_00770	ENOG4105CHR	reductase
CO731_00771	ENOG4105CAT	Cytidine monophosphate kinase
CO731_00772	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CO731_00775	ENOG4105C7K	acetolactate synthase
CO731_00776	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CO731_00777	ENOG4108JEH	abc transporter atp-binding protein
CO731_00778	ENOG4105E89	ABC transporter
CO731_00779	ENOG4105DSP	amino acid AbC transporter
CO731_00781	ENOG4105DG4	malate L-lactate dehydrogenase
CO731_00783	ENOG4105VDW	Csbd family
CO731_00786	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CO731_00788	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CO731_00790	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
CO731_00791	ENOG4108Z5K	methylglyoxal synthase
CO731_00792	ENOG4105CHC	glucokinase (EC 2.7.1.2)
CO731_00794	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CO731_00795	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CO731_00797	ENOG4105CKK	Glycosyl transferase, family 2
CO731_00798	ENOG4107S2Z	UPF0761 membrane protein
CO731_00803	ENOG4105K6T	rare lipoprotein A
CO731_00805	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
CO731_00806	ENOG4108RTU	Aldolase
CO731_00807	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
CO731_00808	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
CO731_00810	ENOG4105D7Z	glutathione synthase
CO731_00812	ENOG4105BZU	Histidine kinase
CO731_00813	ENOG4105C0P	Mg chelatase subunit ChlI
CO731_00851	ENOG4105CDU	Replicative dna helicase
CO731_00858	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CO731_00859	ENOG4105C0P	Mg chelatase subunit ChlI
CO731_00864	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CO731_00867	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CO731_00868	ENOG4105CFG	Acts as a chaperone (By similarity)
CO731_00869	ENOG4105D0M	Protease HtpX homolog
CO731_00874	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CO731_00876	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CO731_00877	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CO731_00878	ENOG41082BR	50S ribosomal protein L35
CO731_00880	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CO731_00882	ENOG4105DKK	Benzoate
CO731_00885	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CO731_00886	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CO731_00887	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CO731_00888	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CO731_00891	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CO731_00893	ENOG4108S0S	Nucleotidyl transferase
CO731_00894	ENOG4105EHM	Aminoglycoside phosphotransferase
CO731_00895	ENOG4105I8F	Histidine kinase
CO731_00896	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CO731_00897	ENOG41080Z8	PHOSPHOCARRIER protein
CO731_00898	ENOG4108EQA	pts system
CO731_00900	ENOG4105EB3	Histidine kinase
CO731_00901	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CO731_00902	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CO731_00903	ENOG4108YZN	class I peptide chain release factor
CO731_00904	ENOG4109066	lysm domain bon superfamily protein
CO731_00905	ENOG4105CF1	Alkylated DNA repair protein
CO731_00906	ENOG4105CS9	pantothenic acid kinase
CO731_00907	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
CO731_00908	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CO731_00909	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CO731_00910	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CO731_00912	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CO731_00913	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CO731_00915	ENOG4108VRQ	UPF0314 protein
CO731_00917	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CO731_00919	ENOG4105CFF	transcriptional regulator
CO731_00924	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CO731_00925	ENOG4107RZZ	dna polymerase iii epsilon subunit
CO731_00926	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CO731_00927	ENOG4105E2X	shikimate dehydrogenase
CO731_00928	ENOG4108UHJ	MAF-like protein
CO731_00929	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CO731_00930	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CO731_00931	ENOG4108YXA	Membrane
CO731_00932	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CO731_00933	ENOG4105C7Z	Conserved Protein
CO731_00934	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CO731_00935	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CO731_00936	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
CO731_00937	ENOG4107QJE	Chromosome Partitioning Protein
CO731_00938	ENOG4105FA0	parb-like partition protein
CO731_00949	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CO731_00950	ENOG4105D4P	Coproporphyrinogen iii oxidase
CO731_00951	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CO731_00955	ENOG4107QX3	carboxylase
CO731_00956	ENOG4107ZYJ	bioY protein
CO731_00957	ENOG4105CFF	transcriptional regulator
CO731_00959	ENOG4105BZM	domain protein
CO731_00960	ENOG4105CDH	Citrulline--aspartate ligase
CO731_00966	ENOG4105BZU	Histidine kinase
CO731_00968	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CO731_00969	ENOG4105K5M	30s ribosomal protein S16
CO731_00971	ENOG4105FFC	UPF0187 protein
CO731_00973	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CO731_00977	ENOG4105CQ0	ABC transporter
CO731_00978	ENOG4105KAF	membrAne
CO731_00979	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CO731_00982	ENOG4108176	endoribonuclease L-psp
CO731_00984	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CO731_00985	ENOG4108MES	Periplasmic binding protein
CO731_00986	ENOG4105DQ5	transport system permease protein
CO731_00987	ENOG4108IHU	transport system permease protein
CO731_00988	ENOG4105E0A	ABC, transporter
CO731_00990	ENOG4105CV8	reductase
CO731_00991	ENOG4105F27	Major Facilitator
CO731_00992	ENOG4105EXG	Transcriptional regulator
CO731_01003	ENOG4105VEQ	Cold shock protein
CO731_01007	ENOG4105CI0	Citrate lyase
CO731_01011	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
CO731_01012	ENOG4105C0B	DNA polymerase III (alpha subunit)
CO731_01013	ENOG4105W49	UPF0434 protein
CO731_01014	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CO731_01015	ENOG4105K63	Thioredoxin
CO731_01018	ENOG4105CHR	reductase
CO731_01019	ENOG4105DIA	mandelate racemase muconate lactonizing
CO731_01020	ENOG4105ERH	Fumarylacetoacetate hydrolase
CO731_01022	ENOG4105CNN	ABC, transporter
CO731_01023	ENOG4105C2J	ABC transporter
CO731_01025	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
CO731_01027	ENOG4105NWF	RbsD or FucU transport
CO731_01028	ENOG4108JQ7	(ABC) transporter
CO731_01030	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_01031	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_01032	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_01033	ENOG4108IGT	Dipeptidase
CO731_01037	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CO731_01039	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CO731_01042	ENOG4105KZX	Pterin carbinolamine dehydratase
CO731_01043	ENOG4105KJF	protein tyrosine phosphatase
CO731_01044	ENOG4105M7V	2'-5' rna ligase
CO731_01046	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CO731_01048	ENOG4105HFZ	Membrane
CO731_01050	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CO731_01051	ENOG4105C26	Dehydrogenase
CO731_01052	ENOG4105CTU	Proline racemase
CO731_01056	ENOG4105BZU	Histidine kinase
CO731_01063	ENOG4105D6Z	AFG1 family ATPase
CO731_01064	ENOG4105UXD	Outer membrane lipoprotein
CO731_01065	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CO731_01066	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CO731_01067	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CO731_01068	ENOG4107835	probably involved in intracellular septation (By similarity)
CO731_01071	ENOG4107QX9	Thiol disulfide interChange protein
CO731_01073	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CO731_01074	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CO731_01075	ENOG4107QM5	aconitate hydratase
CO731_01076	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CO731_01077	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CO731_01078	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CO731_01079	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CO731_01080	ENOG4105C7S	Dehydrogenase
CO731_01083	ENOG4105N14	lysine exporter protein LysE YggA
CO731_01085	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CO731_01086	ENOG4107QN2	dihydrolipoyl dehydrogenase
CO731_01089	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CO731_01090	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CO731_01093	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CO731_01097	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CO731_01098	ENOG4106PMH	Extracellular solute-binding protein family 3
CO731_01099	ENOG4108HW4	amino acid AbC transporter
CO731_01103	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CO731_01104	ENOG4106TD9	Diguanylate cyclase
CO731_01106	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
CO731_01108	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CO731_01110	ENOG4105E33	succinate dehydrogenase
CO731_01112	ENOG4108YXG	UPF0502 protein
CO731_01115	ENOG4108Z9K	Osmotically inducible protein
CO731_01117	ENOG4105C29	acyl-CoA thioesterase
CO731_01118	ENOG4108YZA	Nitrogen regulatory protein pii
CO731_01119	ENOG4105BZU	Histidine kinase
CO731_01124	ENOG4105CNU	cell division protein FtsK
CO731_01125	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CO731_01128	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CO731_01131	ENOG4105ETT	transcriptional Regulator, LysR family
CO731_01135	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CO731_01136	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CO731_01137	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CO731_01142	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CO731_01145	ENOG4105EXC	Acyl-transferase
CO731_01146	ENOG4107QKS	N-acylglucosamine 2-epimerase
CO731_01147	ENOG4105ECK	Fatty Acid Desaturase
CO731_01149	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CO731_01150	ENOG4105BZS	acriflavin resistance protein
CO731_01152	ENOG4108HQS	Glycine betaine
CO731_01153	ENOG4108IJ7	Glycine betaine
CO731_01155	ENOG4106WF9	DNA-binding transcriptional regulator TorR
CO731_01156	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CO731_01157	ENOG4105BZU	Histidine kinase
CO731_01158	ENOG4108SV3	Tmao reductase system periplasmic protein tort
CO731_01159	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_01160	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CO731_01161	ENOG4105C26	Dehydrogenase
CO731_01165	ENOG4108JBU	Outer membrane protein Omp31
CO731_01169	ENOG410856B	UPF0235 protein
CO731_01171	ENOG4105F0N	pyrophosphate phospho-hydrolase
CO731_01175	ENOG4108V0P	LemA family
CO731_01180	ENOG4105CZQ	inner membrane transport protein YdhC
CO731_01182	ENOG4105DGW	oligopeptidase A
CO731_01187	ENOG4105C7I	Dehydrogenase
CO731_01188	ENOG4105DEU	major facilitator superfamily
CO731_01189	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CO731_01191	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CO731_01192	ENOG4105D0M	Protease HtpX homolog
CO731_01196	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CO731_01197	ENOG4105P0T	Usg family
CO731_01202	ENOG4105DFA	alanine racemase domain protein
CO731_01203	ENOG4105C8T	Leucyl-tRNA synthetase
CO731_01207	ENOG4108YXU	transcriptional regulator AsnC family
CO731_01208	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CO731_01209	ENOG4105C25	Primosomal protein n'
CO731_01214	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CO731_01216	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CO731_01217	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CO731_01218	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CO731_01219	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CO731_01221	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CO731_01224	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
CO731_01226	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
CO731_01228	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CO731_01229	ENOG4108KHF	Resistance protein
CO731_01231	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
CO731_01232	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CO731_01234	ENOG4108JQ7	(ABC) transporter
CO731_01235	ENOG4105DZC	cytosine deaminase
CO731_01236	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_01238	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
CO731_01239	ENOG4105C3U	ABC transporter
CO731_01244	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CO731_01245	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CO731_01249	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CO731_01250	ENOG4105DFP	Integrase
CO731_01267	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CO731_01268	ENOG4105K46	50S ribosomal protein l27
CO731_01271	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CO731_01272	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CO731_01273	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CO731_01274	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CO731_01279	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CO731_01281	ENOG4105CN1	protease
CO731_01283	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CO731_01284	ENOG4105NXH	GreA GreB family elongation factor
CO731_01286	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CO731_01290	ENOG4105C26	Dehydrogenase
CO731_01293	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CO731_01294	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CO731_01296	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_01297	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CO731_01298	ENOG4105C0Z	ABC transporter
CO731_01299	ENOG4108IV0	ABC, transporter
CO731_01302	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CO731_01304	ENOG4106UW1	Major Facilitator superfamily
CO731_01306	ENOG4105BZS	acriflavin resistance protein
CO731_01312	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CO731_01313	ENOG4107SC1	transglycosylase
CO731_01314	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CO731_01316	ENOG4105BZU	Histidine kinase
CO731_01318	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CO731_01319	ENOG41082R8	50S ribosomal protein l32
CO731_01322	ENOG4108NVM	synthesis repressor PhaR
CO731_01323	ENOG4105CHU	acetyl-coa acetyltransferase
CO731_01324	ENOG4105CHR	reductase
CO731_01328	ENOG4108Z4U	Ferredoxin
CO731_01329	ENOG4108VJ1	Transcriptional regulator (CarD family
CO731_01330	ENOG4105CDA	abc transporter atp-binding protein
CO731_01331	ENOG4105E5Q	amino acid AbC transporter
CO731_01332	ENOG4105EAB	amino acid AbC transporter
CO731_01333	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CO731_01335	ENOG4107T0D	ABC, transporter
CO731_01337	ENOG4105DP9	ABC transporter
CO731_01339	ENOG4105C5H	ABC transporter
CO731_01343	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CO731_01346	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CO731_01349	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CO731_01353	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CO731_01354	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CO731_01356	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CO731_01357	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CO731_01359	ENOG4108ZZF	transport protein (ExbD)
CO731_01360	ENOG4105E02	MotA TolQ exbB proton channel
CO731_01362	ENOG4107YD3	Thioesterase
CO731_01364	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
CO731_01365	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CO731_01368	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CO731_01372	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CO731_01376	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_01380	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CO731_01381	ENOG4105ECY	inositol monophosphatase
CO731_01382	ENOG4108UT2	hemolysin iii
CO731_01387	ENOG4105CTD	carboxy-peptidase
CO731_01390	ENOG4105BZ1	(ABC) transporter
CO731_01391	ENOG41082FS	50S ribosomal protein L31
CO731_01393	ENOG4107S9F	NmrA family
CO731_01395	ENOG4105CPF	Cell wall formation (By similarity)
CO731_01397	ENOG4105CDY	transcriptional regulatory protein
CO731_01399	ENOG4105BZU	Histidine kinase
CO731_01405	ENOG4105CDU	Replicative dna helicase
CO731_01406	ENOG4105EE5	Membrane protein terC
CO731_01407	ENOG4105D48	metallophosphoesterase
CO731_01414	ENOG4105E0X	reductase
CO731_01416	ENOG4105Y2X	UPF0335 protein
CO731_01420	ENOG4105CA9	Pyruvate kinase
CO731_01421	ENOG4108MUZ	hydrolase
CO731_01422	ENOG4105M0T	TPR Repeat-Containing Protein
CO731_01425	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CO731_01429	ENOG4105MHT	Transcriptional regulator, ARSR family
CO731_01439	ENOG4105BZU	Histidine kinase
CO731_01448	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CO731_01459	ENOG4108Z66	YbaK ebsC protein
CO731_01462	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CO731_01471	ENOG4107R1Y	fructose-bisphosphate aldolase
CO731_01472	ENOG4105BZA	Phosphoglycerate kinase
CO731_01480	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CO731_01483	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
CO731_01504	ENOG4108KQ5	Integrase catalytic subunit
CO731_01531	ENOG4105FDF	Could be involved in DNA repair (By similarity)
CO731_01532	ENOG4105DQE	DNA ligase
CO731_01542	ENOG4105BZU	Histidine kinase
CO731_01544	ENOG4105C8U	phosphate abc transporter
CO731_01546	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CO731_01547	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CO731_01548	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CO731_01549	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CO731_01552	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
CO731_01553	ENOG4105DFW	ABC transporter
CO731_01554	ENOG4107RNG	ABC transporter
CO731_01555	ENOG4105C2J	ABC transporter
CO731_01559	ENOG4105BZU	Histidine kinase
CO731_01561	ENOG41074H6	response regulator
CO731_01565	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CO731_01576	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
CO731_01577	ENOG4105FBA	Phospholipase Carboxylesterase
CO731_01580	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
CO731_01581	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CO731_01582	ENOG4108KXV	response regulator
CO731_01585	ENOG4107RCV	ABC transporter, permease
CO731_01586	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_01590	ENOG4105ECY	inositol monophosphatase
CO731_01591	ENOG4105ECY	inositol monophosphatase
CO731_01594	ENOG4105ETE	Transcriptional regulator (LacI family
CO731_01596	ENOG4105C4Y	ABC transporter
CO731_01597	ENOG4107RCV	ABC transporter, permease
CO731_01599	ENOG4105W39	Membrane
CO731_01601	ENOG4107R16	Multicopper oxidase
CO731_01606	ENOG4105C59	p-type ATPase
CO731_01607	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CO731_01608	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CO731_01610	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
CO731_01615	ENOG4105CVJ	phosphoglycerate mutase
CO731_01616	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_01617	ENOG4108I5D	sulfate abc transporter
CO731_01619	ENOG4106KNT	transcriptional regulator
CO731_01622	ENOG4105UIB	(ABC) transporter
CO731_01623	ENOG4105C2J	ABC transporter
CO731_01625	ENOG4105C6F	GntR Family Transcriptional Regulator
CO731_01630	ENOG4107QPD	alcohol dehydrogenase
CO731_01631	ENOG4105C4W	S-formylglutathione hydrolase
CO731_01632	ENOG4105DWF	phosphomethylpyrimidine kinase
CO731_01634	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CO731_01637	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CO731_01638	ENOG4107R0V	Pyruvate dehydrogenase
CO731_01639	ENOG4105CPP	Dehydrogenase, E1 component
CO731_01640	ENOG4107QSN	dihydrolipoamide acetyltransferase
CO731_01641	ENOG4107QN2	dihydrolipoyl dehydrogenase
CO731_01642	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CO731_01649	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_01650	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_01651	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_01653	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CO731_01655	ENOG4105BZC	d-serine deaminase
CO731_01656	ENOG4105W8I	Transcriptional regulator
CO731_01657	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CO731_01659	ENOG4105DWV	Homoserine O-trans-acetylase
CO731_01661	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_01662	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
CO731_01663	ENOG4105C0Z	ABC transporter
CO731_01664	ENOG4108IUZ	ABC transporter
CO731_01665	ENOG4105P8G	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
CO731_01666	ENOG4105VTR	Integrase
CO731_01682	ENOG4105D7A	ATP-binding protein
CO731_01688	ENOG4105CH2	amidohydrolase
CO731_01689	ENOG4105DZ1	carboxypeptidase
CO731_01690	ENOG4105CKI	cobalamin synthesis protein
CO731_01691	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CO731_01693	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CO731_01696	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CO731_01697	ENOG4105D49	3-dehydroquinate synthase
CO731_01698	ENOG4108JU6	CBS domain protein
CO731_01709	ENOG4105EX9	Membrane
CO731_01710	ENOG4105KDC	50s ribosomal protein l28
CO731_01714	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CO731_01715	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CO731_01717	ENOG4107TE5	Lipid kinase
CO731_01719	ENOG4105CBN	LysR family transcriptional regulator
CO731_01720	ENOG4105CVG	Homoserine O-transsuccinylase
CO731_01721	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CO731_01725	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CO731_01729	ENOG4105CAK	Cell division ATP-binding protein ftsE
CO731_01731	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CO731_01732	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CO731_01734	ENOG4107NQ8	LysR family Transcriptional regulator
CO731_01737	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CO731_01739	ENOG4105CH7	arginosuccinase
CO731_01740	ENOG4107ZT5	Thiol disulfide interchange protein
CO731_01741	ENOG4108IJG	ABC transporter substrate-binding protein
CO731_01742	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
CO731_01744	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_01745	ENOG4105BZU	Histidine kinase
CO731_01746	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CO731_01747	ENOG4105C10	Electron transfer flavoprotein
CO731_01748	ENOG4105BZJ	Electron transfer flavoprotein
CO731_01752	ENOG4105E1F	short-chain dehydrogenase reductase
CO731_01754	ENOG4108IPJ	Membrane
CO731_01756	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CO731_01760	ENOG4108UM1	dedA family
CO731_01762	ENOG4105SKE	transcriptional Regulator LysR family
CO731_01763	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
CO731_01764	ENOG4105CHR	reductase
CO731_01768	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CO731_01773	ENOG4105CHU	acetyl-coa acetyltransferase
CO731_01782	ENOG4108XFH	Transcriptional regulator
CO731_01783	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
CO731_01793	ENOG4105CYM	Glutathione S-transferase
CO731_01794	ENOG4107RFB	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CO731_01796	ENOG4105F04	LysR family Transcriptional regulator
CO731_01798	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CO731_01805	ENOG4105DUM	transcriptional regulator, lysR family
CO731_01820	ENOG4105E4C	Lytic transglycosylase catalytic
CO731_01825	ENOG4107QJE	Chromosome Partitioning Protein
CO731_01854	ENOG4106F59	XRE family Transcriptional regulator
CO731_01855	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
CO731_01860	ENOG41079YP	Citrate utilization protein b
CO731_01861	ENOG4107EFR	Flavocytochrome c
CO731_01862	ENOG4107QM5	aconitate hydratase
CO731_01866	ENOG4105EGI	Transcriptional regulator
CO731_01867	ENOG4108JQ1	Dehydrogenase
CO731_01868	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CO731_01869	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CO731_01873	ENOG4105F04	LysR family Transcriptional regulator
CO731_01877	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CO731_01880	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CO731_01881	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CO731_01883	ENOG4108JGH	Tetr family transcriptional regulator
CO731_01885	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CO731_01887	ENOG4105M6F	mutator MutT protein
CO731_01891	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CO731_01892	ENOG4105VW4	glutaredoxin 3
CO731_01897	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CO731_01898	ENOG4105CFH	Aspartokinase
CO731_01899	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
CO731_01900	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CO731_01901	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CO731_01903	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CO731_01905	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
CO731_01906	ENOG4105FQP	Beta-lactamase
CO731_01907	ENOG4108YYD	acetyltransferase
CO731_01912	ENOG4105BZU	Histidine kinase
CO731_01913	ENOG4105E4C	Lytic transglycosylase catalytic
CO731_01929	ENOG4108ZQS	transposase
CO731_01931	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_01933	ENOG4105CKU	formyltetrahydrofolate synthetase
CO731_01934	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CO731_01937	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_01938	ENOG4105C0Z	ABC transporter
CO731_01939	ENOG4108IV0	ABC, transporter
CO731_01940	ENOG4108YZ9	Urea amidohydrolase subunit gamma
CO731_01941	ENOG4105CQM	Urea amidohydrolase subunit alpha
CO731_01942	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
CO731_01943	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CO731_01945	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CO731_01946	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CO731_01950	ENOG4105CFF	transcriptional regulator
CO731_01951	ENOG4107RET	Isocitrate lyase
CO731_01952	ENOG4107QPD	alcohol dehydrogenase
CO731_01953	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
CO731_01956	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
CO731_01957	ENOG4105C1G	acyl-Coa dehydrogenase
CO731_01959	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CO731_01961	ENOG4105C5W	Aldolase
CO731_01962	ENOG4108WYP	Transcriptional regulator
CO731_01963	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
CO731_01964	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
CO731_01966	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
CO731_01967	ENOG4107TTD	cytosine deaminase
CO731_01968	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CO731_01970	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_01971	ENOG4105CHR	reductase
CO731_01976	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CO731_01982	ENOG4105KME	endoribonuclease L-psp
CO731_01986	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CO731_01989	ENOG4105ETE	Transcriptional regulator (LacI family
CO731_01992	ENOG4105CNN	ABC, transporter
CO731_01993	ENOG4105C2J	ABC transporter
CO731_01994	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CO731_01997	ENOG4105K64	Glycosyl transferase, family 2
CO731_01998	ENOG4108SHN	Glycosyl transferase, family 2
CO731_02003	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
CO731_02004	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CO731_02005	ENOG410829K	Lysine exporter protein (Lyse ygga)
CO731_02008	ENOG4105CMG	Carbohydrate kinase
CO731_02010	ENOG4105C93	Xylose Isomerase
CO731_02012	ENOG4105U0R	haloacid dehalogenase-like hydrolase
CO731_02013	ENOG4105ECQ	AraC Family Transcriptional Regulator
CO731_02014	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
CO731_02015	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
CO731_02016	ENOG4105C1G	acyl-Coa dehydrogenase
CO731_02017	ENOG4105CD5	CoA-binding domain protein
CO731_02018	ENOG4105E39	Enoyl-CoA hydratase
CO731_02020	ENOG4108JQ6	ABC transporter
CO731_02021	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_02028	ENOG4108Z2U	ureidoglycolate hydrolase
CO731_02029	ENOG4105S0E	allantoin catabolism protein
CO731_02031	ENOG4105VT2	5-hydroxyisourate hydrolase
CO731_02033	ENOG4105C7W	Xanthine dehydrogenase
CO731_02035	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
CO731_02036	ENOG4107YPT	transcriptional regulator
CO731_02039	ENOG4105CC0	LysR family Transcriptional regulator
CO731_02041	ENOG4107QUY	Guanine deaminase
CO731_02042	ENOG41090KN	UPF0303 protein
CO731_02046	ENOG4105CFQ	glutamine synthetase
CO731_02047	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CO731_02052	ENOG4105CKI	cobalamin synthesis protein
CO731_02054	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
CO731_02056	ENOG4105ETE	Transcriptional regulator (LacI family
CO731_02057	ENOG4108Z86	Glutamine amidotransferase
CO731_02058	ENOG4105CH5	extracellular solute-binding protein, family 7
CO731_02059	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CO731_02069	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CO731_02070	ENOG4105W8H	transhydrogenase (subunit alpha
CO731_02071	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CO731_02072	ENOG4108NIW	Leucine export protein LeuE
CO731_02075	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
CO731_02077	ENOG4105K5G	30S ribosomal protein S21
CO731_02079	ENOG4105EU0	Major facilitator Superfamily
CO731_02080	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CO731_02081	ENOG4105DDR	sarcosine oxidase (Beta subunit)
CO731_02085	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_02090	ENOG4105BZS	acriflavin resistance protein
CO731_02094	ENOG4105CUB	amino acid
CO731_02101	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_02102	ENOG4105DND	Transcriptional regulator
CO731_02103	ENOG4107TYH	extracellular solute-binding protein family 1
CO731_02104	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_02105	ENOG4105D81	ABC transporter, permease
CO731_02106	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
CO731_02107	ENOG4105C26	Dehydrogenase
CO731_02110	ENOG4107P2S	Transcriptional regulator
CO731_02112	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
CO731_02113	ENOG4105E39	Enoyl-CoA hydratase
CO731_02114	ENOG4105C26	Dehydrogenase
CO731_02115	ENOG4108JP0	extracellular solute-binding protein family 1
CO731_02118	ENOG4108IJ9	(ABC) transporter
CO731_02120	ENOG4105CHR	reductase
CO731_02122	ENOG4105C3R	Methionine synthase
CO731_02134	ENOG4108ZNX	Heat shock protein
CO731_02136	ENOG4105D74	hydrolase
CO731_02137	ENOG4105C5W	Aldolase
CO731_02141	ENOG4105CVE	Lytic murein transglycosylase
CO731_02143	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
CO731_02144	ENOG4105NAE	bifunctional deaminase-reductase domain protein
CO731_02146	ENOG4105C2X	Arabinose 5-phosphate isomerase
CO731_02148	ENOG4107QX8	SPFH domain, Band 7 family protein
CO731_02150	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CO731_02151	ENOG4105CGH	5'-nucleotidase
CO731_02152	ENOG4105ZWB	Outer membrane lipoprotein
CO731_02153	ENOG4105FE5	Homospermidine synthase
CO731_02158	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CO731_02159	ENOG4105EAQ	(twin-arginine translocation) pathway signal
CO731_02160	ENOG4108UHU	Aldolase
CO731_02161	ENOG4105T4X	n-acetylmuramoyl-l-alanine amidase
CO731_02162	ENOG4105C72	UPF0176 protein
CO731_02164	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CO731_02171	ENOG4105EJC	lysr family transcriptional regulator
CO731_02173	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CO731_02181	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CO731_02182	ENOG4105D7B	Flagellar biosynthesis protein flha
CO731_02187	ENOG4107SFI	Major Facilitator superfamily
CO731_02188	ENOG4105VS8	Flagellar biosynthetic protein fliq
CO731_02189	ENOG410822I	Flagellar hook capping protein
CO731_02190	ENOG4105KHD	Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation (By similarity)
CO731_02191	ENOG41060XD	Flagellar protein FlaF
CO731_02198	ENOG4108S15	chemotaxis, protein
CO731_02199	ENOG4105ER2	Ompa motb domain protein
CO731_02202	ENOG4107W75	Flagellin
CO731_02203	ENOG4107W75	Flagellin
CO731_02205	ENOG4107W75	Flagellin
CO731_02206	ENOG4107W75	Flagellin
CO731_02207	ENOG4107W75	Flagellin
CO731_02208	ENOG4105CN7	Flagellar biosynthetic protein FliP
CO731_02210	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CO731_02212	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CO731_02213	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
CO731_02214	ENOG4105CGA	flagellar basal-body rod protein FlgG
CO731_02215	ENOG4105X50	flagellar hook-basal body complex protein fliE
CO731_02216	ENOG4108ZC9	flagellar basal-body rod protein flgc
CO731_02217	ENOG4105SFI	flagellar basal-body rod protein
CO731_02219	ENOG4108JIR	Flagellum-specific ATP synthase
CO731_02220	ENOG4105KTQ	flagellar basal-body rod protein
CO731_02222	ENOG4107RD7	Flagellar Motor Protein, MotA
CO731_02223	ENOG4105I8W	motor switch protein
CO731_02224	ENOG4105DD5	Flagellar motor switch protein
CO731_02225	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CO731_02226	ENOG4105D00	flagellar biosynthetic protein flhB
CO731_02227	ENOG4105QDQ	
CO731_02229	ENOG4105VJY	transcriptional regulator
CO731_02231	ENOG41067B5	Histone deacetylase superfamily protein
CO731_02232	ENOG4108JGH	Tetr family transcriptional regulator
CO731_02233	ENOG4105EFZ	amidohydrolase
CO731_02234	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_02235	ENOG4105F38	ABC transporter, permease
CO731_02236	ENOG4105D38	putrescine abc transporter
CO731_02241	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CO731_02243	ENOG4105VQD	rieske 2fe-2S domain-containing protein
CO731_02245	ENOG4105ETE	Transcriptional regulator (LacI family
CO731_02251	ENOG4108HWV	)-transporter
CO731_02253	ENOG4105D7K	pfkb domain protein
CO731_02254	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CO731_02255	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
CO731_02257	ENOG4105DH8	myo-inositol catabolism
CO731_02258	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CO731_02260	ENOG4107QZV	Type I secretion membrane fusion protein
CO731_02264	ENOG4105WH1	Two component transcriptional regulator luxr family
CO731_02268	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_02273	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_02274	ENOG4105FC8	fad dependent oxidoreductase
CO731_02276	ENOG4105FD8	phosphonate metabolism protein PhnM
CO731_02277	ENOG4108TXN	phosphonate metabolism protein
CO731_02280	ENOG4106AFQ	Histidine kinase
CO731_02281	ENOG4105D5T	phosphonate abc transporter
CO731_02283	ENOG4105D6U	Sodium Glutamate Symporter
CO731_02285	ENOG4105HRV	phosphonate c-p lyase system protein phnl
CO731_02286	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
CO731_02289	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
CO731_02299	ENOG4105CMR	udp-glucose 4-epimerase
CO731_02302	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CO731_02304	ENOG4107T8Q	Glycosyl transferase (Group 1
CO731_02313	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CO731_02317	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CO731_02320	ENOG4105KVH	Transcriptional regulator
CO731_02322	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
CO731_02323	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CO731_02328	ENOG41080HT	Transcriptional regulator, arsr family
CO731_02332	ENOG4105CHF	Glutathione S-transferase
CO731_02333	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CO731_02338	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CO731_02340	ENOG4108KK1	membrane protein AbrB duplication
CO731_02346	ENOG4105CRQ	synthase (Component I)
CO731_02347	ENOG4105EHG	Permease protein
CO731_02349	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CO731_02350	ENOG4105F27	Major Facilitator
CO731_02352	ENOG4105FR1	rard protein
CO731_02353	ENOG4105DZG	Dehydrogenase
CO731_02359	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CO731_02363	ENOG4105CKU	formyltetrahydrofolate synthetase
CO731_02369	ENOG4107104	thymidine kinase
CO731_02371	ENOG4108HQS	Glycine betaine
CO731_02372	ENOG4108IJ7	Glycine betaine
CO731_02376	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
CO731_02377	ENOG4105M74	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CO731_02382	ENOG4105VEQ	Cold shock protein
CO731_02387	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CO731_02390	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CO731_02393	ENOG4105C1J	atp-dependent rna helicase
CO731_02396	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CO731_02399	ENOG4108Z4X	TRANSCRIPTIONal
CO731_02400	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CO731_02402	ENOG4105BZ1	(ABC) transporter
CO731_02403	ENOG4105BZ1	(ABC) transporter
CO731_02404	ENOG4105BZ1	(ABC) transporter
CO731_02406	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CO731_02408	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CO731_02409	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CO731_02413	ENOG4107QUT	magnesium and cobalt transport protein CorA
CO731_02414	ENOG4108JBU	Outer membrane protein Omp31
CO731_02416	ENOG4105C3G	gtp-binding protein
CO731_02417	ENOG4105NAE	bifunctional deaminase-reductase domain protein
CO731_02419	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CO731_02420	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CO731_02424	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CO731_02427	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CO731_02429	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CO731_02432	ENOG4108Z7R	Chaperone CsaA
CO731_02434	ENOG4105D01	(LipO)protein
CO731_02435	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CO731_02436	ENOG4108UMI	ABC transporter, permease
CO731_02437	ENOG4105E0F	Histidine kinase
CO731_02439	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CO731_02440	ENOG41090HR	transcriptional regulator
CO731_02441	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CO731_02443	ENOG4105C5X	domain protein
CO731_02445	ENOG4105VEQ	Cold shock protein
CO731_02447	ENOG4105VEQ	Cold shock protein
CO731_02450	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
CO731_02452	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CO731_02453	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
CO731_02461	ENOG4107R6D	beta-lactam binding protein AmpH
CO731_02467	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CO731_02472	ENOG4105W3H	MtN3 and saliva related transmembrane protein
CO731_02480	ENOG4105CXK	mandelate racemase muconate lactonizing
CO731_02482	ENOG4105NAU	thioesterase Superfamily protein
CO731_02495	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CO731_02498	ENOG4108SHN	Glycosyl transferase, family 2
CO731_02501	ENOG4105F7P	transcriptional regulator AsnC family
CO731_02502	ENOG4105C3M	thioredoxin reductase
CO731_02503	ENOG4105CBN	LysR family transcriptional regulator
CO731_02506	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CO731_02511	ENOG4105CHM	Aminotransferase
CO731_02512	ENOG4105BZU	Histidine kinase
CO731_02514	ENOG4105CYM	Glutathione S-transferase
CO731_02517	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CO731_02519	ENOG4108R6G	acetyltransferase
CO731_02525	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CO731_02526	ENOG4105YVS	arsR family transcriptional regulator
CO731_02527	ENOG4105F9N	Major Facilitator Superfamily
CO731_02529	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_02533	ENOG4105CGZ	zinc metallopeptidase
CO731_02534	ENOG4107QM2	Aldo Keto reductase
CO731_02537	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CO731_02540	ENOG4105CH2	amidohydrolase
CO731_02541	ENOG4105EAM	Na Pi-cotransporter
CO731_02542	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CO731_02543	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CO731_02550	ENOG4108Q5F	Tetr family transcriptional regulator
CO731_02557	ENOG4108Z9Z	response to DNA damage stimulus
CO731_02559	ENOG4108TEB	UPF0114 protein
CO731_02560	ENOG4105UYK	outer membrane protein a
CO731_02561	ENOG4108ZZ3	UPF0260 protein
CO731_02563	ENOG4105MPN	Membrane
CO731_02567	ENOG4105D38	putrescine abc transporter
CO731_02568	ENOG4105F38	ABC transporter, permease
CO731_02569	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_02573	ENOG4108WFR	AraC Family Transcriptional Regulator
CO731_02575	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CO731_02576	ENOG4105G9V	cytochrome C
CO731_02584	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CO731_02585	ENOG4105MKQ	Monovalent cation H antiporter subunit C
CO731_02586	ENOG4105D65	subunit l
CO731_02589	ENOG4105W4C	monovalent cation H antiporter subunit F
CO731_02590	ENOG4105SC1	monovalent cation H antiporter subunit E
CO731_02592	ENOG4105D5Q	Arginine ornithine antiporter
CO731_02593	ENOG4105D5Q	Arginine ornithine antiporter
CO731_02594	ENOG4105CEU	Arginine dihydrolase
CO731_02602	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
CO731_02603	ENOG4105D8G	Major Facilitator superfamily
CO731_02605	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CO731_02607	ENOG4105F04	LysR family Transcriptional regulator
CO731_02609	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CO731_02610	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
CO731_02612	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_02614	ENOG4105C2J	ABC transporter
CO731_02615	ENOG4108IV0	ABC, transporter
CO731_02616	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
CO731_02618	ENOG4105Q56	cytochrome P450
CO731_02622	ENOG4105ERH	Fumarylacetoacetate hydrolase
CO731_02623	ENOG4107S8A	protein TIM barrel
CO731_02624	ENOG4105CTX	dehydratase
CO731_02625	ENOG4105CTX	dehydratase
CO731_02627	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_02629	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_02630	ENOG4107PP3	Acetylornithine deacetylase
CO731_02632	ENOG4105C28	cystathionine
CO731_02633	ENOG4107QXX	ABC transporter
CO731_02634	ENOG4105EZ7	amino acid ABC transporter
CO731_02635	ENOG4105DRP	amino acid AbC transporter
CO731_02636	ENOG4105CDA	abc transporter atp-binding protein
CO731_02639	ENOG4105DZ2	Transcriptional regulator
CO731_02640	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CO731_02642	ENOG4107Y2X	deaminase
CO731_02650	ENOG4105DTQ	mandelate racemase muconate lactonizing
CO731_02651	ENOG4106KNT	transcriptional regulator
CO731_02653	ENOG4105C26	Dehydrogenase
CO731_02654	ENOG4107W6X	Transcriptional regulator
CO731_02655	ENOG4107RN6	Monooxygenase
CO731_02657	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CO731_02666	ENOG4105IJJ	transcriptional regulator, crp fnr family
CO731_02675	ENOG4108VKQ	nitriC oxide reductase
CO731_02677	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
CO731_02679	ENOG4105D4P	Coproporphyrinogen iii oxidase
CO731_02684	ENOG4105I5W	Transporter
CO731_02686	ENOG4108IFG	nitrite reductase, (NAD(P)H)
CO731_02691	ENOG4105CKK	Glycosyl transferase, family 2
CO731_02698	ENOG4105BZU	Histidine kinase
CO731_02699	ENOG4105WH1	Two component transcriptional regulator luxr family
CO731_02700	ENOG410829K	Lysine exporter protein (Lyse ygga)
CO731_02705	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CO731_02709	ENOG4107QXX	ABC transporter
CO731_02710	ENOG4105EZ7	amino acid ABC transporter
CO731_02711	ENOG4105DRP	amino acid AbC transporter
CO731_02716	ENOG4108IJ6	ABC transporter
CO731_02718	ENOG4108I5D	sulfate abc transporter
CO731_02719	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
CO731_02721	ENOG4108JQB	penicillin-binding protein 1C
CO731_02723	ENOG4105CFU	surface antigen
CO731_02725	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_02727	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_02730	ENOG4105BZ8	glutamate synthase
CO731_02731	ENOG4107SJI	Dehydrogenase
CO731_02734	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
CO731_02736	ENOG4108R86	Transcriptional regulator
CO731_02737	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CO731_02738	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
CO731_02739	ENOG4105CD3	dihydroorotase
CO731_02741	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CO731_02742	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
CO731_02746	ENOG4105CKK	Glycosyl transferase, family 2
CO731_02747	ENOG4105C7K	acetolactate synthase
CO731_02749	ENOG4105E5G	Alpha beta hydrolase fold
CO731_02750	ENOG4105DA5	(ABC) transporter
CO731_02751	ENOG4105E3A	(ABC) transporter
CO731_02762	ENOG4108R96	Methyltransferase, YaeB family
CO731_02764	ENOG4105SYT	Methylenetetrahydrofolate reductase
CO731_02768	ENOG4105CMR	udp-glucose 4-epimerase
CO731_02775	ENOG4105T38	integral membrane protein
CO731_02776	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CO731_02780	ENOG4105C28	cystathionine
CO731_02781	ENOG4108206	Cell division protein mraZ
CO731_02782	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CO731_02785	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CO731_02787	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CO731_02788	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CO731_02790	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CO731_02791	ENOG4105DFU	Cell wall formation (By similarity)
CO731_02792	ENOG4105D4A	Cell wall formation (By similarity)
CO731_02793	ENOG4105CPF	Cell wall formation (By similarity)
CO731_02794	ENOG4108UFP	Essential cell division protein (By similarity)
CO731_02795	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CO731_02796	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CO731_02797	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CO731_02798	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO731_02801	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CO731_02804	ENOG4105DC7	peptidase M24
CO731_02804	ENOG4105DC7	peptidase M24
CO731_02805	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CO731_02813	ENOG4105C4R	Atp-dependent dna helicase
CO731_02818	ENOG4105CQB	FAD linked oxidase domain protein
CO731_02827	ENOG4105C2C	drug resistance transporter, Bcr CflA
CO731_02834	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CO731_02838	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CO731_02840	ENOG4107QJR	hflk protein
CO731_02841	ENOG4105EPW	hflc protein
CO731_02843	ENOG4105C0H	protease
CO731_02846	ENOG4108YYQ	gCN5-related N-acetyltransferase
CO731_02847	ENOG4105EAC	phosphoserine phosphatase
CO731_02848	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CO731_02849	ENOG4106TD9	Diguanylate cyclase
CO731_02854	ENOG4105C7K	acetolactate synthase
CO731_02855	ENOG4108ZP8	Acetolactate synthase small subunit
CO731_02863	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
CO731_02866	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CO731_02867	ENOG4105DFH	Transport of potassium into the cell (By similarity)
CO731_02869	ENOG4105UYK	outer membrane protein a
CO731_02870	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CO731_02871	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CO731_02877	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CO731_02878	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CO731_02880	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CO731_02882	ENOG4105CSV	Glutaminase
CO731_02883	ENOG4105DSF	transport protein
CO731_02887	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
CO731_02888	ENOG4108IJ6	ABC transporter
CO731_02889	ENOG4105ECW	sulfate abc transporter
CO731_02890	ENOG4108I5D	sulfate abc transporter
CO731_02891	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
CO731_02892	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CO731_02893	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CO731_02894	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CO731_02896	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
CO731_02908	ENOG4105T0Z	Conserved Protein
CO731_02909	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CO731_02910	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CO731_02911	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CO731_02912	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CO731_02913	ENOG4105GKE	subunit e
CO731_02914	ENOG4107QIZ	NADH dehydrogenase
CO731_02915	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CO731_02916	ENOG4107R0R	NADH dehydrogenase subunit g
CO731_02917	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CO731_02918	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CO731_02919	ENOG4105DF2	NADH dehydrogenase subunit j
CO731_02920	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CO731_02921	ENOG4105D65	subunit l
CO731_02922	ENOG4105C8S	subunit m
CO731_02923	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CO731_02924	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CO731_02928	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CO731_02930	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CO731_02931	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CO731_02937	ENOG4105CJW	magnesium transporter
CO731_02942	ENOG4108NH8	Cation transport protein
CO731_02946	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CO731_02947	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CO731_02952	ENOG4105CHM	Aminotransferase
CO731_02953	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
CO731_02957	ENOG4105KME	endoribonuclease L-psp
CO731_02960	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_02962	ENOG4105DDR	sarcosine oxidase (Beta subunit)
CO731_02963	ENOG4105EGS	Mechanosensitive ion channel
CO731_02968	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CO731_02974	ENOG4105ECQ	AraC Family Transcriptional Regulator
CO731_02977	ENOG4107NQ8	LysR family Transcriptional regulator
CO731_02986	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CO731_02991	ENOG4108Q52	Methyltransferase cognate corrinoid protein
CO731_02992	ENOG4105F5V	trimethylamine methyltransferase
CO731_02994	ENOG4105JXH	GntR family transcriptional regulator
CO731_02995	ENOG4105DJ2	Major Facilitator Superfamily
CO731_02996	ENOG4105CBX	hi0933 family
CO731_02997	ENOG4105EMN	RNA polymerase sigma factor
CO731_02998	ENOG4105CP2	von willebrand factor, type a
CO731_03003	ENOG4105EIG	urea carboxylase-associated protein 1
CO731_03007	ENOG4105H1N	peptidase, M24
CO731_03009	ENOG4105KME	endoribonuclease L-psp
CO731_03010	ENOG4105F5V	trimethylamine methyltransferase
CO731_03013	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CO731_03018	ENOG4105C1G	acyl-Coa dehydrogenase
CO731_03019	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CO731_03025	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_03027	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_03028	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CO731_03034	ENOG4105DB1	molybdopterin oxidoreductase
CO731_03035	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CO731_03037	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
CO731_03039	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CO731_03040	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CO731_03041	ENOG4105J3Q	acyl carrier protein
CO731_03044	ENOG4105C26	Dehydrogenase
CO731_03046	ENOG4105CA0	peroxidase
CO731_03047	ENOG4105EW9	transcriptional regulator AsnC family
CO731_03055	ENOG4106QJH	hemin transport protein
CO731_03056	ENOG4107R4I	Periplasmic binding protein
CO731_03057	ENOG4105EHG	Permease protein
CO731_03058	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CO731_03059	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
CO731_03060	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CO731_03064	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CO731_03066	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
CO731_03069	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CO731_03071	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
CO731_03072	ENOG4107QPR	SAICAR synthetase
CO731_03076	ENOG4105KPV	Transcriptional regulator
CO731_03078	ENOG4106BRA	Membrane
CO731_03087	ENOG4105DMF	Dehydrogenase
CO731_03088	ENOG4105WD1	Membrane
CO731_03090	ENOG4105JEU	Glycosyl transferase, family 2
CO731_03109	ENOG4108YXQ	IS66 Orf2 family protein
CO731_03111	ENOG4105E4C	Lytic transglycosylase catalytic
CO731_03119	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
CO731_03120	ENOG4105CDA	abc transporter atp-binding protein
CO731_03121	ENOG4105EZ7	amino acid ABC transporter
CO731_03122	ENOG4105E5Q	amino acid AbC transporter
CO731_03123	ENOG4106TNF	Periplasmic binding protein
CO731_03126	ENOG4105VJY	transcriptional regulator
CO731_03135	ENOG4105KVH	Transcriptional regulator
CO731_03137	ENOG4107NQ8	LysR family Transcriptional regulator
CO731_03141	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CO731_03143	ENOG4105BZU	Histidine kinase
CO731_03144	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CO731_03148	ENOG4108KQ5	Integrase catalytic subunit
CO731_03150	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CO731_03152	ENOG4105C8U	phosphate abc transporter
CO731_03153	ENOG4105E2Z	phosphate ABC transporter (Permease
CO731_03154	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CO731_03155	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CO731_03156	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CO731_03160	ENOG4105CAU	Arsenical resistance protein, ArsH
CO731_03161	ENOG4105K89	arsenate reductase
CO731_03162	ENOG4105D6J	arsenicaL-resistance protein
CO731_03165	ENOG4108A65	Transcriptional regulator
CO731_03168	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
CO731_03174	ENOG4105C59	p-type ATPase
CO731_03179	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CO731_03184	ENOG4105VN1	Heat shock protein
CO731_03187	ENOG4105C5B	carbamate kinase
CO731_03195	ENOG4108W63	CRP FNR family transcriptional regulator
CO731_03203	ENOG4105CD5	CoA-binding domain protein
CO731_03209	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CO731_03214	ENOG4105CY0	Metallo-Beta-Lactamase
CO731_03215	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CO731_03216	ENOG4107QRI	Phosphoketolase
CO731_03218	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CO731_03219	ENOG41065SU	Two-component system sensor kinase
CO731_03221	ENOG4108KQ5	Integrase catalytic subunit
CO731_03223	ENOG4105C5B	carbamate kinase
CO731_03224	ENOG4105DBV	ornithine carbamoyltransferase
CO731_03225	ENOG4105CEU	Arginine dihydrolase
CO731_03226	ENOG4105D5Q	Arginine ornithine antiporter
CO731_03229	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CO731_03232	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CO731_03233	ENOG4105BZU	Histidine kinase
CO731_03235	ENOG4108K3A	Glutathione S-transferase
CO731_03236	ENOG4108RG0	uracil-dna glycosylase
CO731_03237	ENOG4108XM1	transcriptional regulator AsnC family
CO731_03239	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CO731_03244	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CO731_03247	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CO731_03250	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CO731_03251	ENOG41067TZ	transcriptional regulator, MarR family
CO731_03252	ENOG41082A2	Alpha beta hydrolase
CO731_03253	ENOG4105C72	UPF0176 protein
CO731_03254	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CO731_03257	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CO731_03258	ENOG4105E66	phosphoriboisomerase A
CO731_03261	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
CO731_03264	ENOG4105BZU	Histidine kinase
CO731_03266	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
CO731_03267	ENOG41080IJ	Diacylglycerol kinase
CO731_03271	ENOG4105C4K	Nad synthetase
CO731_03274	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CO731_03276	ENOG41082BM	Transcriptional regulator, arsr family
CO731_03277	ENOG4105BZ1	(ABC) transporter
CO731_03278	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CO731_03280	ENOG4105C6K	Malic enzyme
CO731_03284	ENOG4107S8C	mandelate racemase muconate lactonizing
CO731_03286	ENOG4105DHJ	ABC, transporter
CO731_03288	ENOG4108SNX	Mammalian cell entry related domain protein
CO731_03291	ENOG4107Z7P	Ferredoxin
CO731_03292	ENOG4105CAY	ferredoxin--nadp reductase
CO731_03295	ENOG4105KRF	dihydroneopterin aldolase
CO731_03296	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CO731_03299	ENOG4108UXN	response regulator
CO731_03300	ENOG4105BZU	Histidine kinase
CO731_03303	ENOG4105W0E	50S ribosomal protein L33
CO731_03304	ENOG4105S8Q	sugar efflux transporter
CO731_03307	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CO731_03308	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CO731_03310	ENOG4105C79	DNA protecting protein DprA
CO731_03311	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CO731_03312	ENOG4105CD3	dihydroorotase
CO731_03313	ENOG4105CXT	aspartate transcarbamylase
CO731_03314	ENOG4105CSU	acyl-Coa dehydrogenase
CO731_03316	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CO731_03317	ENOG4107T8T	UPF0173 metal-dependent hydrolase
CO731_03319	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CO731_03320	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CO731_03322	ENOG41080C8	DUF218 domain
CO731_03324	ENOG4105EJQ	L-serine dehydratase
CO731_03327	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CO731_03328	ENOG4105DZ1	carboxypeptidase
CO731_03330	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CO731_03332	ENOG4105BZU	Histidine kinase
CO731_03337	ENOG4105K59	histidine triad (HIT) protein
CO731_03340	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
CO731_03344	ENOG4105CE9	30S ribosomal protein S2
CO731_03345	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CO731_03346	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CO731_03347	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CO731_03348	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CO731_03349	ENOG4105KNE	Phosphatidate cytidylyltransferase
CO731_03350	ENOG4105DZP	Membrane-associated zinc metalloprotease
CO731_03351	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CO731_03352	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CO731_03353	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CO731_03354	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CO731_03355	ENOG4105GYT	Protein of unknown function (DUF1009)
CO731_03356	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CO731_03357	ENOG4105BZN	citrate synthase
CO731_03358	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CO731_03359	ENOG4108EC8	DNA internalization-related competence protein ComEC
CO731_03360	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CO731_03361	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CO731_03362	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CO731_03363	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CO731_03364	ENOG4107QYG	anthranilate phosphoribosyltransferase
CO731_03365	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
CO731_03366	ENOG4105CP7	Triose-phosphate isomerase
CO731_03367	ENOG4107EJC	Preprotein translocase subunit SecG
CO731_03369	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CO731_03372	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CO731_03376	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CO731_03377	ENOG4106ABQ	septum formation initiator
CO731_03378	ENOG4108JYK	Dehydrogenase
CO731_03379	ENOG4105CPP	Dehydrogenase, E1 component
CO731_03380	ENOG4105C7S	Dehydrogenase
CO731_03382	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
CO731_03383	ENOG4107QN2	dihydrolipoyl dehydrogenase
CO731_03385	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CO731_03386	ENOG4108Z1B	Cyclase dehydrase
CO731_03388	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CO731_03390	ENOG4105CUX	Signal transduction histidine kinase
CO731_03391	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CO731_03392	ENOG4105ES5	Histidine kinase
CO731_03393	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CO731_03394	ENOG4105C1A	potassium transporter peripheral membrane
CO731_03395	ENOG4105F0I	Aminotransferase
CO731_03396	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CO731_03397	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CO731_03398	ENOG4105DXN	mazG family
CO731_03399	ENOG41082CG	Protein CrcB homolog
CO731_03400	ENOG4105EI2	Pseudouridine synthase
CO731_03401	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CO731_03403	ENOG4107R5B	glutamine synthetase
CO731_03408	ENOG4105C5F	glutamine synthetase
CO731_03409	ENOG4108YZA	Nitrogen regulatory protein pii
CO731_03410	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CO731_03413	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CO731_03418	ENOG4108QIF	Phosphoesterase, PA-phosphatase related
CO731_03419	ENOG4108UUM	single-stranded DNA-binding protein
CO731_03422	ENOG41081FY	multiple antibiotic resistance (MarC)-related
CO731_03425	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CO731_03426	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CO731_03427	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CO731_03429	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CO731_03430	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CO731_03442	ENOG4105E98	transcriptional regulator DeoR family
CO731_03443	ENOG4105W6J	BA14K family
CO731_03449	ENOG4107QIV	Cytochrome c biogenesis protein
CO731_03450	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CO731_03451	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CO731_03453	ENOG4105CB5	ATP-dependent DNA helicase recG
CO731_03458	ENOG4105E43	Extracellular solute-binding protein, family 5
CO731_03461	ENOG4105RK9	auxin efflux carrier
CO731_03462	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CO731_03463	ENOG4105VE1	Phosphatidylcholine synthase
CO731_03464	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
CO731_03465	ENOG4108JQ9	ABC transporter
CO731_03466	ENOG4105UIB	(ABC) transporter
CO731_03469	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CO731_03470	ENOG4108ZCF	integral membrane protein
CO731_03472	ENOG4105DR5	peptidase
CO731_03476	ENOG4108WHA	ompa motb domain protein
CO731_03478	ENOG4105CS6	Rhs element vgr protein
CO731_03487	ENOG4108WHA	ompa motb domain protein
CO731_03498	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CO731_03511	ENOG4105DZ1	carboxypeptidase
CO731_03512	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CO731_03513	ENOG4107QRG	dna polymerase iii
CO731_03515	ENOG4105F8V	Hydrolase, tatD family
CO731_03516	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CO731_03518	ENOG4105F9F	transposase
CO731_03519	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CO731_03520	ENOG4105DVW	rieske (2Fe-2S)
CO731_03521	ENOG4105ETT	transcriptional Regulator, LysR family
CO731_03522	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
CO731_03524	ENOG4108JQ6	ABC transporter
CO731_03525	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_03526	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_03527	ENOG4107VFR	oxidoreductase
CO731_03531	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_03532	ENOG4105WIU	sarcosine oxidase delta subunit
CO731_03533	ENOG4105DDR	sarcosine oxidase (Beta subunit)
CO731_03536	ENOG4105CMG	Carbohydrate kinase
CO731_03539	ENOG4108FN7	Aldo keto reductase
CO731_03541	ENOG4105CNN	ABC, transporter
CO731_03548	ENOG4107S76	domain protein
CO731_03549	ENOG4107S76	domain protein
CO731_03550	ENOG4105D1H	recombination factor protein RarA
CO731_03551	ENOG4105C0H	protease
CO731_03552	ENOG4108ZT0	50S ribosomal protein l17
CO731_03553	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CO731_03554	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CO731_03555	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CO731_03556	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CO731_03557	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CO731_03558	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CO731_03559	ENOG41084HQ	50S ribosomal protein L30
CO731_03560	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CO731_03561	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CO731_03562	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CO731_03563	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CO731_03564	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CO731_03565	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CO731_03566	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CO731_03567	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CO731_03568	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CO731_03569	ENOG41083MP	50s ribosomal protein l29
CO731_03570	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CO731_03571	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CO731_03572	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CO731_03573	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CO731_03574	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CO731_03575	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CO731_03576	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CO731_03577	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CO731_03578	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CO731_03579	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CO731_03580	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CO731_03581	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CO731_03582	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CO731_03584	ENOG4105DVH	amino acid
CO731_03585	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CO731_03586	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CO731_03587	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CO731_03588	ENOG4108VZM	50s ribosomal protein L10
CO731_03589	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CO731_03590	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CO731_03596	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CO731_03599	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CO731_03601	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CO731_03602	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
CO731_03603	ENOG41060W2	glyoxylate carboligase
CO731_03606	ENOG4108UIN	ybak prolyl-trna synthetase associated region
CO731_03609	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CO731_03611	ENOG4108ZG0	Ompa motb domain protein
CO731_03614	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CO731_03618	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CO731_03619	ENOG4105C03	ribonuclease
CO731_03623	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CO731_03626	ENOG4105CGH	5'-nucleotidase
CO731_03628	ENOG4105DCF	alanine dehydrogenase
CO731_03629	ENOG4105UYK	outer membrane protein a
CO731_03633	ENOG4105KHC	sulfurtransferase
CO731_03634	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CO731_03635	ENOG4105C6T	cysteine synthase
CO731_03636	ENOG4108R85	Short chain dehydrogenase
CO731_03638	ENOG4105C1J	atp-dependent rna helicase
CO731_03643	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CO731_03645	ENOG4105CM6	amino acid regulated cytosolic protein
CO731_03646	ENOG4106K28	UPF0283 membrane protein
CO731_03649	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CO731_03652	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CO731_03654	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CO731_03657	ENOG4105C0B	DNA polymerase III (alpha subunit)
CO731_03658	ENOG4107QPD	alcohol dehydrogenase
CO731_03660	ENOG4108UPT	UPF0178 protein
CO731_03663	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CO731_03664	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_03665	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CO731_03666	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CO731_03668	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CO731_03671	ENOG4105CI0	Citrate lyase
CO731_03672	ENOG4105EW6	flavin reductase domain protein, FMN-binding
CO731_03673	ENOG41069NU	Nitroreductase
CO731_03675	ENOG4105C22	threonyL-tRNA synthetase
CO731_03677	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CO731_03679	ENOG4105ETT	transcriptional Regulator, LysR family
CO731_03681	ENOG4105EUJ	GTP cyclohydrolase i
CO731_03682	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CO731_03683	ENOG4105D78	K07001 NTE family protein
CO731_03684	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CO731_03685	ENOG4105CBT	Fructose-1,6-bisphosphatase
CO731_03686	ENOG4105D6E	homoserine dehydrogenase
CO731_03687	ENOG4105CHM	Aminotransferase
CO731_03689	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CO731_03696	ENOG4105JVC	membrAne
CO731_03699	ENOG4105DRR	Transcriptional regulator, GntR family
CO731_03701	ENOG4108KQ5	Integrase catalytic subunit
CO731_03704	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CO731_03705	ENOG4108PVQ	transcriptional regulator
CO731_03706	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CO731_03708	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CO731_03709	ENOG4105W5Q	DNA repair protein (RadC
CO731_03714	ENOG4107QZV	Type I secretion membrane fusion protein
CO731_03715	ENOG4108JJ6	Type I secretion system ATPase
CO731_03718	ENOG4105WH1	Two component transcriptional regulator luxr family
CO731_03722	ENOG4108KQ5	Integrase catalytic subunit
CO731_03729	ENOG4105W5Q	DNA repair protein (RadC
CO731_03730	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CO731_03732	ENOG4107TYR	Glycosyl Transferase
CO731_03738	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
CO731_03739	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CO731_03745	ENOG4108K5P	(LipO)protein
CO731_03746	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CO731_03747	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CO731_03748	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CO731_03749	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CO731_03751	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CO731_03753	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CO731_03754	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CO731_03755	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CO731_03757	ENOG4105C75	arginyL-tRNA synthetase
CO731_03758	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CO731_03762	ENOG4105C2W	permease
CO731_03763	ENOG4105CGK	Exodeoxyribonuclease III
CO731_03764	ENOG4108P7N	Exopolysaccharide production negative regulator
CO731_03766	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CO731_03769	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CO731_03773	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
CO731_03782	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CO731_03783	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CO731_03784	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CO731_03785	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CO731_03790	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CO731_03791	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CO731_03793	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CO731_03794	ENOG4105YCT	UPF0386 protein
CO731_03795	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CO731_03800	ENOG4108Z0R	Transferase
CO731_03803	ENOG4105D7W	serine acetyltransferase
CO731_03804	ENOG4106YT9	Enoyl-CoA hydratase
CO731_03808	ENOG4105VEQ	Cold shock protein
CO731_03809	ENOG4108UYE	Lactoylglutathione lyase
CO731_03811	ENOG4105C7B	Threonine dehydratase
CO731_03812	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CO731_03815	ENOG4105CPN	adenine deaminase
CO731_03816	ENOG4105CQZ	Histidine kinase
CO731_03817	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CO731_03828	ENOG4105CEV	competence damage-inducible protein
CO731_03830	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CO731_03832	ENOG4107RTZ	reductase
CO731_03833	ENOG41082IR	Excinuclease ABC C subunit domain protein
CO731_03834	ENOG41082IR	Excinuclease ABC C subunit domain protein
CO731_03837	ENOG4105HMI	Membrane
CO731_03838	ENOG4105DUM	transcriptional regulator, lysR family
CO731_03840	ENOG4105E98	transcriptional regulator DeoR family
CO731_03843	ENOG4107TTQ	Alpha beta hydrolase fold
CO731_03850	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CO731_03851	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
CO731_03857	ENOG4105KXX	peptidase s58 dmpa
CO731_03860	ENOG4105C83	adenylosuccinate lyase
CO731_03861	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CO731_03863	ENOG4105KVH	Transcriptional regulator
CO731_03866	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CO731_03870	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CO731_03871	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CO731_03872	ENOG4105DD7	kinase (PfkB family
CO731_03873	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
CO731_03876	ENOG4108Z4V	iron-sulfur cluster assembly
CO731_03877	ENOG4105VG1	fes assembly suf system protein
CO731_03879	ENOG4105JRK	feS assembly protein SufD
CO731_03880	ENOG4105C3K	feS assembly ATPase SufC
CO731_03883	ENOG4105C3J	Cysteine desulfurase
CO731_03884	ENOG4105DHZ	alpha beta
CO731_03888	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CO731_03889	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CO731_03891	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CO731_03892	ENOG4105DR5	peptidase
CO731_03901	ENOG4108IYU	L-aspartate oxidase
CO731_03902	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CO731_03903	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CO731_03904	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CO731_03906	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CO731_03907	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CO731_03911	ENOG4108JQ7	(ABC) transporter
CO731_03912	ENOG4105C3U	ABC transporter
CO731_03913	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_03914	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_03915	ENOG4105WBV	Transcriptional regulator
CO731_03916	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_03919	ENOG4105K70	DNA-binding protein
CO731_03921	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CO731_03922	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CO731_03931	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CO731_03932	ENOG4108UJD	30S ribosomal protein S9
CO731_03934	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
CO731_03935	ENOG4105CYW	agmatinase
CO731_03938	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
CO731_03944	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CO731_03945	ENOG4105D3Q	Sugar transferase
CO731_03952	ENOG4105WJX	transcriptional regulator MERR family
CO731_03953	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CO731_03954	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CO731_03955	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CO731_03958	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CO731_03959	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CO731_03961	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
CO731_03962	ENOG4108IJ8	ABC transporter
CO731_03963	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
CO731_03964	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
CO731_03965	ENOG4105DXI	Major Facilitator superfamily
CO731_03966	ENOG4107XZX	Involved in the transcription termination process (By similarity)
CO731_03967	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CO731_03969	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CO731_03970	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CO731_03971	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CO731_03972	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CO731_03975	ENOG4105E39	Enoyl-CoA hydratase
CO731_03976	ENOG4105D52	delta-aminolevulinic acid dehydratase
CO731_03978	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CO731_03980	ENOG4105IPI	Membrane
CO731_03981	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CO731_03983	ENOG4105C9M	aspartyl-trna synthetase
CO731_03986	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CO731_03991	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CO731_03992	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CO731_03997	ENOG4105DZS	Phenylacetate-CoA ligase
CO731_04002	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_04004	ENOG4105F38	ABC transporter, permease
CO731_04007	ENOG4105UIB	(ABC) transporter
CO731_04008	ENOG4105CNN	ABC, transporter
CO731_04009	ENOG4108JQ9	ABC transporter
CO731_04011	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CO731_04017	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CO731_04018	ENOG4108KB1	transcriptional regulator, arac family
CO731_04019	ENOG4105UIB	(ABC) transporter
CO731_04020	ENOG41083U2	ABC transporter, permease
CO731_04021	ENOG4108JQ9	ABC transporter
CO731_04022	ENOG4105DIH	basic membrane
CO731_04024	ENOG4108K2B	transcriptional regulator
CO731_04025	ENOG4108QE0	porin outer membrane protein
CO731_04027	ENOG4105C5I	Dehydrogenase
CO731_04030	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_04031	ENOG4105D65	subunit l
CO731_04032	ENOG4108ZE9	Monovalent cation H antiporter subunit C
CO731_04033	ENOG4107R4Z	monovalent cation h antiporter subunit d
CO731_04034	ENOG4105SC1	monovalent cation H antiporter subunit E
CO731_04035	ENOG4105W4C	monovalent cation H antiporter subunit F
CO731_04036	ENOG4105KJM	monovalent cation h antiporter subunit g
CO731_04039	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_04041	ENOG4105CAQ	asparagine synthetase
CO731_04042	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CO731_04052	ENOG4105E2R	ROK family
CO731_04059	ENOG4105C7N	Xanthine uracil vitamin C permease
CO731_04061	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CO731_04062	ENOG4108IJ9	(ABC) transporter
CO731_04063	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_04065	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
CO731_04068	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CO731_04069	ENOG4107QWG	2-Nitropropane dioxygenase
CO731_04070	ENOG41060IM	Heme exporter protein
CO731_04071	ENOG4105BZ1	(ABC) transporter
CO731_04072	ENOG4105E2V	Glycosyltransferase 36
CO731_04074	ENOG41090B9	response to stress
CO731_04075	ENOG4105CGP	Urocanate hydratase
CO731_04077	ENOG4105C84	Histidine ammonia-lyase
CO731_04078	ENOG4105CI2	imidazolone-5-propionate hydrolase
CO731_04081	ENOG4105M4H	endoribonuclease L-psp
CO731_04082	ENOG4105DIK	(ABC) transporter
CO731_04083	ENOG4105CC5	ABC transporter
CO731_04084	ENOG4105DSE	periplasmic solute binding protein
CO731_04091	ENOG4107XDQ	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CO731_04093	ENOG4105CPQ	Dehydrogenase
CO731_04094	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CO731_04096	ENOG4107WEA	mandelate racemase muconate lactonizing
CO731_04098	ENOG4105C1G	acyl-Coa dehydrogenase
CO731_04101	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CO731_04104	ENOG4105F5V	trimethylamine methyltransferase
CO731_04105	ENOG4105EQ2	LysR family Transcriptional regulator
CO731_04106	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CO731_04108	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CO731_04109	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CO731_04112	ENOG4107TK4	histidinol-phosphate phosphatase
CO731_04113	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CO731_04119	ENOG4106H78	methyltransferase
CO731_04121	ENOG4108Z6B	deaminase
CO731_04123	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CO731_04126	ENOG4105DTN	riboflavin biosynthesis protein ribF
CO731_04129	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CO731_04130	ENOG4105CW7	secretion protein, HlyD family
CO731_04132	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CO731_04133	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CO731_04134	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CO731_04136	ENOG41067RQ	csbd family
CO731_04137	ENOG4105C9Q	fumarate hydratase class II
CO731_04138	ENOG4108VBZ	doxx family
CO731_04141	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CO731_04143	ENOG4105MSY	salicylate hydroxylase
CO731_04145	ENOG4105CDA	abc transporter atp-binding protein
CO731_04146	ENOG4105DRP	amino acid AbC transporter
CO731_04147	ENOG4105EZ7	amino acid ABC transporter
CO731_04148	ENOG4107QXX	ABC transporter
CO731_04150	ENOG4105C28	cystathionine
CO731_04158	ENOG41073TP	transcriptional regulator
CO731_04159	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CO731_04160	ENOG4105C01	Dihydroxy-acid dehydratase
CO731_04161	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CO731_04162	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
CO731_04163	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CO731_04164	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
CO731_04165	ENOG4108RTU	Aldolase
CO731_04169	ENOG4105C02	permease
CO731_04171	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CO731_04172	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CO731_04175	ENOG4108J2R	molybdopterin oxidoreductase
CO731_04176	ENOG4105C5H	ABC transporter
CO731_04180	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CO731_04181	ENOG4108MNP	Glycoprotein polysaccharide metabolism
CO731_04182	ENOG4108ZAF	Molybdopterin
CO731_04185	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CO731_04186	ENOG4105CHR	reductase
CO731_04188	ENOG4108U78	Glutathione S-transferase
CO731_04191	ENOG4105D6S	protein involved in catabolism of external DNA
CO731_04196	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CO731_04201	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CO731_04202	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CO731_04203	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CO731_04204	ENOG4105DSJ	YicC domain protein
CO731_04205	ENOG4105HHA	aminodeoxychorismate lyase
CO731_04206	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CO731_04207	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CO731_04209	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CO731_04210	ENOG4107T7U	Sulfatase
CO731_04211	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CO731_04212	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CO731_04213	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CO731_04214	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CO731_04215	ENOG4105KK4	UPF0060 membrane protein
CO731_04221	ENOG4107RGD	Major Facilitator superfamily
CO731_04222	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CO731_04224	ENOG4105PDP	Short chain dehydrogenase
CO731_04229	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_04231	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
CO731_04234	ENOG4108JJ7	ABC transporter
CO731_04236	ENOG4109066	lysm domain bon superfamily protein
CO731_04237	ENOG4108URH	decarboxylase
CO731_04239	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CO731_04245	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
CO731_04246	ENOG4105C8N	cysteinyl-tRNA synthetase
CO731_04251	ENOG4105E09	nadh pyrophosphatase
CO731_04255	ENOG4105CD3	dihydroorotase
CO731_04256	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CO731_04257	ENOG4108R7K	Metal Dependent Phosphohydrolase
CO731_04258	ENOG4108RXX	maleylacetoacetate isomerase
CO731_04262	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CO731_04264	ENOG41082BM	Transcriptional regulator, arsr family
CO731_04265	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CO731_04266	ENOG4108R6G	acetyltransferase
CO731_04268	ENOG4105EMN	RNA polymerase sigma factor
CO731_04270	ENOG4108BI7	Toxic component of a toxin-antitoxin (TA) module. A
CO731_04275	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
CO731_04279	ENOG4107Y80	Major Facilitator superfamily
CO731_04281	ENOG4105EMU	Dehydrogenase
CO731_04288	ENOG4105EST	Metal Dependent Phosphohydrolase
CO731_04290	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CO731_04296	ENOG4108W6C	Dehydrogenase
CO731_04298	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CO731_04299	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CO731_04300	ENOG4105C3F	Signal peptidase i
CO731_04301	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CO731_04302	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CO731_04304	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CO731_04307	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CO731_04308	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CO731_04309	ENOG4107SC1	transglycosylase
CO731_04310	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
CO731_04317	ENOG4105UKP	Protein of unknown function (DUF1778)
CO731_04325	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CO731_04328	ENOG4105C3F	Signal peptidase i
CO731_04330	ENOG4105E4C	Lytic transglycosylase catalytic
CO731_04333	ENOG4107TTQ	Alpha beta hydrolase fold
CO731_04334	ENOG4105DND	Transcriptional regulator
CO731_04348	ENOG4105DND	Transcriptional regulator
CO731_04351	ENOG4105BZS	acriflavin resistance protein
CO731_04355	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
CO731_04371	ENOG4105C1G	acyl-Coa dehydrogenase
CO731_04375	ENOG4107QX3	carboxylase
CO731_04378	ENOG4105D3R	alkyl hydroperoxide reductase
CO731_04382	ENOG4105CYM	Glutathione S-transferase
CO731_04385	ENOG4105FYV	Amp nucleosidase
CO731_04388	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CO731_04390	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CO731_04395	ENOG4105CD8	aminopeptidase N
CO731_04396	ENOG4105BZU	Histidine kinase
CO731_04398	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CO731_04399	ENOG4106F60	Histidine kinase
CO731_04400	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CO731_04401	ENOG4105C0H	protease
CO731_04402	ENOG4105KWW	Biogenesis protein
CO731_04403	ENOG4105DA4	cytochrome c-type biogenesis protein
CO731_04404	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CO731_04405	ENOG4106FI7	cytochrome c-type biogenesis protein
CO731_04407	ENOG41062D9	Histidine kinase
CO731_04408	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CO731_04413	ENOG4108JQC	penicillin-binding protein 1A
CO731_04420	ENOG4105BZU	Histidine kinase
CO731_04422	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CO731_04424	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CO731_04426	ENOG4108YXV	Transcriptional regulator
CO731_04429	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
CO731_04431	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CO731_04432	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CO731_04434	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CO731_04435	ENOG4105D7A	ATP-binding protein
CO731_04437	ENOG41086VY	Fic/DOC family
CO731_04438	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CO731_04440	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
CO731_04441	ENOG4105CHU	acetyl-coa acetyltransferase
CO731_04442	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CO731_04443	ENOG4105CBG	Sulfatase
CO731_04445	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CO731_04446	ENOG4105C26	Dehydrogenase
CO731_04447	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CO731_04448	ENOG4107QKV	phosphomannomutase
CO731_04471	ENOG4108KQ5	Integrase catalytic subunit
CO731_04472	ENOG4105CG3	alpha amylase, catalytic region
CO731_04473	ENOG4108IUM	Glycogen debranching enzyme
CO731_04474	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CO731_04475	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CO731_04476	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CO731_04477	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CO731_04478	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CO731_04479	ENOG4105C2J	ABC transporter
CO731_04480	ENOG4105CNN	ABC, transporter
CO731_04481	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
CO731_04482	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CO731_04483	ENOG4105NWF	RbsD or FucU transport
CO731_04485	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CO731_04486	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CO731_04488	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CO731_04494	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_04496	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CO731_04502	ENOG4105D7Z	glutathione synthase
CO731_04505	ENOG4105W6J	BA14K family
CO731_04510	ENOG4105CQM	Urea amidohydrolase subunit alpha
CO731_04511	ENOG4108F09	Urease subunit gamma beta
CO731_04512	ENOG4107YEM	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
CO731_04514	ENOG4108IV0	ABC, transporter
CO731_04515	ENOG4105C0Z	ABC transporter
CO731_04518	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CO731_04520	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
CO731_04521	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_04524	ENOG4105CYW	agmatinase
CO731_04525	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CO731_04532	ENOG4105BZS	acriflavin resistance protein
CO731_04533	ENOG410624X	efflux transporter, rnd family, mfp subunit
CO731_04535	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CO731_04536	ENOG4107ZQN	disulfide bond
CO731_04538	ENOG4105CEN	a g-specific adenine glycosylase
CO731_04539	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
CO731_04540	ENOG4105CEC	DNA methylase N-4 N-6
CO731_04541	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
CO731_04543	ENOG4105D98	threonine synthase
CO731_04545	ENOG4105D9U	N-acetyltransferase
CO731_04546	ENOG4105BZU	Histidine kinase
CO731_04547	ENOG4108UJU	UPF0301 protein
CO731_04550	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CO731_04551	ENOG4105CUV	Homoserine Kinase
CO731_04552	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CO731_04556	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
CO731_04557	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CO731_04559	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CO731_04560	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CO731_04561	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
CO731_04565	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CO731_04566	ENOG4107QS4	23S rRNA
CO731_04568	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CO731_04569	ENOG4105EUB	pirin domain protein
CO731_04571	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CO731_04573	ENOG4108IG5	Transcriptional regulator
CO731_04577	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CO731_04578	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CO731_04580	ENOG4105CVJ	phosphoglycerate mutase
CO731_04581	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CO731_04582	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CO731_04584	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CO731_04586	ENOG4105CSU	acyl-Coa dehydrogenase
CO731_04589	ENOG4105C12	Phosphoribosylglycinamide synthetase
CO731_04590	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
CO731_04595	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CO731_04598	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CO731_04600	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
CO731_04602	ENOG4105EAH	synthase
CO731_04607	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CO731_04608	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CO731_04612	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CO731_04613	ENOG4105N5Q	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CO731_04614	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CO731_04615	ENOG4105VD1	ATP synthase subunit C
CO731_04616	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CO731_04617	ENOG4107PQ6	Inherit from NOG: atp synthase
CO731_04619	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CO731_04623	ENOG4105WJG	Glutathione
CO731_04625	ENOG4105ETT	transcriptional Regulator, LysR family
CO731_04626	ENOG4105KUZ	arsenate reductase
CO731_04627	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
CO731_04632	ENOG41082BM	Transcriptional regulator, arsr family
CO731_04633	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CO731_04635	ENOG4105EW6	flavin reductase domain protein, FMN-binding
CO731_04636	ENOG4108JQ7	(ABC) transporter
CO731_04637	ENOG4105C3U	ABC transporter
CO731_04638	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_04639	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_04642	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CO731_04644	ENOG4107VIJ	nudix hydrolase
CO731_04645	ENOG4107QXX	ABC transporter
CO731_04649	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
CO731_04652	ENOG410667J	hydrolase
CO731_04655	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CO731_04656	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CO731_04657	ENOG4105C4R	Atp-dependent dna helicase
CO731_04663	ENOG4105C0D	helicase
CO731_04664	ENOG4108I5C	dEAD DEAH box helicase
CO731_04668	ENOG4105FEQ	ParB domain protein nuclease
CO731_04681	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
CO731_04711	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CO731_04712	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CO731_04718	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CO731_04719	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CO731_04721	ENOG4105WMR	Protein CrcB homolog
CO731_04723	ENOG4107R4J	Chloride channel
CO731_04725	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CO731_04731	ENOG4105KAV	tspo and mbr like protein
CO731_04733	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
CO731_04735	ENOG4105C5Q	Transcriptional regulator
CO731_04736	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CO731_04737	ENOG4105P5X	ATP phosphoribosyltransferase regulatory subunit
CO731_04738	ENOG4105CUT	histidyl-tRNA synthetase
CO731_04741	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CO731_04742	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CO731_04744	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CO731_04745	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CO731_04746	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
CO731_04750	ENOG4105CQB	FAD linked oxidase domain protein
CO731_04752	ENOG41073TP	transcriptional regulator
CO731_04755	ENOG4105DDQ	anthranilate synthase
CO731_04760	ENOG4108JGH	Tetr family transcriptional regulator
CO731_04764	ENOG4107NQ8	LysR family Transcriptional regulator
CO731_04765	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CO731_04767	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CO731_04768	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
CO731_04770	ENOG4105BZU	Histidine kinase
CO731_04779	ENOG4105CFG	Acts as a chaperone (By similarity)
CO731_04782	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CO731_04785	ENOG4108KQ5	Integrase catalytic subunit
CO731_04795	ENOG4105CFQ	glutamine synthetase
CO731_04797	ENOG4105CJP	fad dependent oxidoreductase
CO731_04801	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CO731_04802	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CO731_04803	ENOG4105C01	Dihydroxy-acid dehydratase
CO731_04807	ENOG4105C5H	ABC transporter
CO731_04809	ENOG4105ECQ	AraC Family Transcriptional Regulator
CO731_04810	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CO731_04814	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
CO731_04819	ENOG4105II7	pyrroline-5-carboxylate reductase
CO731_04820	ENOG4105F4R	Transcriptional regulator mode
CO731_04821	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CO731_04822	ENOG4105E0C	molybdate abc transporter
CO731_04823	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CO731_04824	ENOG4105HF0	Membrane
CO731_04825	ENOG4105CHU	acetyl-coa acetyltransferase
CO731_04828	ENOG4107HP6	Transcriptional regulator
CO731_04830	ENOG4107RZC	phospholipase d
CO731_04870	ENOG4108N0N	Phage Terminase Large Subunit
CO731_04876	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CO731_04887	ENOG4108KQ5	Integrase catalytic subunit
CO731_04913	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CO731_04915	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CO731_04916	ENOG4108ZTZ	UPF0262 protein
CO731_04918	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CO731_04919	ENOG4108Z03	MAF-like protein
CO731_04924	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CO731_04929	ENOG4105BZU	Histidine kinase
CO731_04960	ENOG4105CAR	Terminase, large subunit
CO731_04970	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CO731_04984	ENOG4105VTR	Integrase
CO731_04985	ENOG4105BZU	Histidine kinase
CO731_04987	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_04988	ENOG41073TP	transcriptional regulator
CO731_04994	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CO731_04995	ENOG4105CKU	formyltetrahydrofolate synthetase
CO731_04996	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_04998	ENOG4105E3J	oxidoreductase
CO731_05001	ENOG4105D7K	pfkb domain protein
CO731_05003	ENOG4105KME	endoribonuclease L-psp
CO731_05004	ENOG4108JEH	abc transporter atp-binding protein
CO731_05005	ENOG4105EAD	ABC transporter
CO731_05006	ENOG4105DRP	amino acid AbC transporter
CO731_05010	ENOG4105S10	periplasmic binding protein
CO731_05011	ENOG4105EHG	Permease protein
CO731_05012	ENOG4105E0A	ABC, transporter
CO731_05013	ENOG4105X1Q	TOBE domain protein
CO731_05016	ENOG4105EAB	amino acid AbC transporter
CO731_05017	ENOG4105GBT	ABC transporter
CO731_05018	ENOG4105E5Q	amino acid AbC transporter
CO731_05019	ENOG4106M28	alanine racemase domain protein
CO731_05020	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CO731_05022	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CO731_05023	ENOG4105CHM	Aminotransferase
CO731_05024	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CO731_05025	ENOG4105BZU	Histidine kinase
CO731_05029	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CO731_05031	ENOG4105DGU	Histone deacetylase
CO731_05034	ENOG4105E89	ABC transporter
CO731_05035	ENOG4105DHP	deoxycytidine triphosphate deaminase
CO731_05037	ENOG4105NWN	ApaG protein
CO731_05038	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CO731_05039	ENOG4105DBV	ornithine carbamoyltransferase
CO731_05040	ENOG4105C8Y	Acetylornithine aminotransferase
CO731_05042	ENOG4105D7N	magnesium and cobalt transport protein CorA
CO731_05043	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CO731_05044	ENOG4105BZU	Histidine kinase
CO731_05045	ENOG4105CSR	polyphosphate kinase 2
CO731_05055	ENOG4106TNF	Periplasmic binding protein
CO731_05057	ENOG4105DK7	lysyl-tRNA synthetase
CO731_05059	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CO731_05061	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CO731_05062	ENOG4105CHU	acetyl-coa acetyltransferase
CO731_05063	ENOG4105C1G	acyl-Coa dehydrogenase
CO731_05065	ENOG4105CSU	acyl-Coa dehydrogenase
CO731_05066	ENOG4107SWG	transcriptional regulator MERR family
CO731_05071	ENOG4107QRT	dEAD DEAH box helicase
CO731_05075	ENOG4107QIM	DNA ligase
CO731_05137	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_05138	ENOG4108JQ7	(ABC) transporter
CO731_05139	ENOG4105C3U	ABC transporter
CO731_05140	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_05141	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_05142	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_05143	ENOG4105CEY	Amp-dependent synthetase and ligase
CO731_05145	ENOG4105C01	Dihydroxy-acid dehydratase
CO731_05154	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CO731_05155	ENOG4107QP8	phosphohexose isomerase
CO731_05157	ENOG4105HEI	LysR family (Transcriptional regulator
CO731_05158	ENOG4105F27	Major Facilitator
CO731_05164	ENOG4105CN8	Transcriptional regulator
CO731_05166	ENOG4107QIZ	NADH dehydrogenase
CO731_05167	ENOG4108JB9	formate dehydrogenase
CO731_05168	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CO731_05170	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CO731_05176	ENOG4105E98	transcriptional regulator DeoR family
CO731_05179	ENOG4105K4I	Scp-like extracellular
CO731_05180	ENOG4105DJP	Membrane
CO731_05182	ENOG4105DZC	cytosine deaminase
CO731_05184	ENOG41083U2	ABC transporter, permease
CO731_05185	ENOG4108JQ9	ABC transporter
CO731_05188	ENOG4105C26	Dehydrogenase
CO731_05189	ENOG4107B2H	carbonic anhydrase
CO731_05193	ENOG41067MG	lrgb family
CO731_05197	ENOG4105KVH	Transcriptional regulator
CO731_05202	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CO731_05204	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CO731_05205	ENOG4105E0X	reductase
CO731_05209	ENOG4105CAS	nag kinase
CO731_05211	ENOG4105EW9	transcriptional regulator AsnC family
CO731_05212	ENOG4105MIR	Phenylalanine 4-monooxygenase
CO731_05214	ENOG4105BZU	Histidine kinase
CO731_05216	ENOG4105NX3	Membrane
CO731_05218	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CO731_05219	ENOG4105KAF	membrAne
CO731_05220	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CO731_05222	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CO731_05224	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CO731_05225	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CO731_05229	ENOG4105KPY	Small multidrug resistance protein
CO731_05232	ENOG4105DEN	Luciferase family
CO731_05234	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CO731_05235	ENOG4105F0V	Cell wall hydrolase
CO731_05237	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CO731_05238	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CO731_05240	ENOG4105E09	nadh pyrophosphatase
CO731_05241	ENOG410645S	MarR family Transcriptional regulator
CO731_05242	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
CO731_05243	ENOG4105CQC	Prephenate dehydratase
CO731_05244	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CO731_05245	ENOG4105G9V	cytochrome C
CO731_05247	ENOG4105E43	Extracellular solute-binding protein, family 5
CO731_05248	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
CO731_05249	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CO731_05251	ENOG4105ZGE	Toxic component of a toxin-antitoxin (TA) module. A
CO731_05252	ENOG4108JQ5	ABC transporter
CO731_05256	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CO731_05270	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CO731_05271	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CO731_05272	ENOG4105E39	Enoyl-CoA hydratase
CO731_05273	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CO731_05275	ENOG4105ECW	sulfate abc transporter
CO731_05276	ENOG4105F38	ABC transporter, permease
CO731_05277	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_05282	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CO731_05284	ENOG4105CQB	FAD linked oxidase domain protein
CO731_05297	ENOG4106TNF	Periplasmic binding protein
CO731_05298	ENOG4105E5Q	amino acid AbC transporter
CO731_05299	ENOG4105EAD	ABC transporter
CO731_05301	ENOG4105CYW	agmatinase
CO731_05302	ENOG4108IJ0	Aspartate ammonia-lyase
CO731_05303	ENOG4105CDA	abc transporter atp-binding protein
CO731_05304	ENOG4105HDK	L-asparaginase
CO731_05305	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
CO731_05307	ENOG4105F38	ABC transporter, permease
CO731_05308	ENOG4105D38	putrescine abc transporter
CO731_05309	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CO731_05311	ENOG4105DTN	riboflavin biosynthesis protein ribF
CO731_05313	ENOG4108U78	Glutathione S-transferase
CO731_05314	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CO731_05315	ENOG4108VQN	4-hydroxyphenylacetate 3-monooxygenase reductase
CO731_05316	ENOG4105EFA	4-hydroxyphenylacetate
CO731_05319	ENOG4105DUM	transcriptional regulator, lysR family
CO731_05320	ENOG4105CWC	Acetylornithine deacetylase
CO731_05321	ENOG4108IJ0	Aspartate ammonia-lyase
CO731_05325	ENOG4108XEG	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CO731_05328	ENOG4107Z6I	Thiamine biosynthesis protein
CO731_05330	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
CO731_05331	ENOG4108UZX	fmn reductase
CO731_05335	ENOG4107XC4	flavin reductase domain protein, FMN-binding
CO731_05341	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
CO731_05342	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CO731_05343	ENOG4105CFG	Acts as a chaperone (By similarity)
CO731_05346	ENOG4108KQ5	Integrase catalytic subunit
CO731_05349	ENOG4105F38	ABC transporter, permease
CO731_05350	ENOG4105D38	putrescine abc transporter
CO731_05352	ENOG4105E1J	oxidoreductase
CO731_05355	ENOG41067QW	Transcriptional regulator
CO731_05357	ENOG4105CXK	mandelate racemase muconate lactonizing
CO731_05358	ENOG4107EJG	GntR family transcriptional regulator
CO731_05362	ENOG4108ZKT	aldose 1-epimerase
CO731_05363	ENOG4108R85	Short chain dehydrogenase
CO731_05366	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CO731_05379	ENOG4107T8Q	Glycosyl transferase (Group 1
CO731_05381	ENOG4105CAY	ferredoxin--nadp reductase
CO731_05382	ENOG4108XM1	transcriptional regulator AsnC family
CO731_05384	ENOG4107S76	domain protein
CO731_05386	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CO731_05389	ENOG4105CHR	reductase
CO731_05392	ENOG4105EUJ	GTP cyclohydrolase i
CO731_05395	ENOG4105DTQ	mandelate racemase muconate lactonizing
CO731_05397	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CO731_05399	ENOG4107QP3	malate synthase g
CO731_05402	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CO731_05405	ENOG41069HH	4-oxalocrotonate tautomerase
CO731_05408	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CO731_05409	ENOG4107TTD	cytosine deaminase
CO731_05412	ENOG4105CKI	cobalamin synthesis protein
CO731_05414	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CO731_05416	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CO731_05417	ENOG4105W8H	transhydrogenase (subunit alpha
CO731_05418	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CO731_05419	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CO731_05421	ENOG4105DU0	nucleoside hydrolase
CO731_05422	ENOG4108DN8	FAD dependent oxidoreductase
CO731_05426	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CO731_05427	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CO731_05428	ENOG4105C5I	Dehydrogenase
CO731_05429	ENOG4105D1Z	hydroxypyruvate reductase
CO731_05431	ENOG4105EYU	Glutamine amido-transferase
CO731_05432	ENOG4105M90	Glutamate synthase alpha subunit domain protein
CO731_05433	ENOG4105CBC	glutamate synthase
CO731_05435	ENOG4105DDR	sarcosine oxidase (Beta subunit)
CO731_05437	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CO731_05440	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CO731_05441	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CO731_05452	ENOG4107R55	ethanolamine transporter
CO731_05456	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CO731_05457	ENOG4105F7P	transcriptional regulator AsnC family
CO731_05458	ENOG4105F9F	transposase
CO731_05460	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CO731_05462	ENOG4108RXX	maleylacetoacetate isomerase
CO731_05463	ENOG4107RCV	ABC transporter, permease
CO731_05465	ENOG4105C4Y	ABC transporter
CO731_05470	ENOG4105EAM	Na Pi-cotransporter
CO731_05473	ENOG4105GRZ	Ycii-related protein
CO731_05474	ENOG4105C5H	ABC transporter
CO731_05476	ENOG4108K3A	Glutathione S-transferase
CO731_05477	ENOG4105KPY	Small multidrug resistance protein
CO731_05483	ENOG4105DVW	rieske (2Fe-2S)
CO731_05489	ENOG4105C2J	ABC transporter
CO731_05490	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
CO731_05491	ENOG4105CNN	ABC, transporter
CO731_05494	ENOG4107S5T	Carbohydrate kinase
CO731_05496	ENOG4105C9F	isomerase
CO731_05497	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
CO731_05498	ENOG4107W7X	Aldolase
CO731_05501	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CO731_05502	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CO731_05503	ENOG4105DEF	Extracellular solute-binding protein, family 5
CO731_05506	ENOG4105CH2	amidohydrolase
CO731_05507	ENOG4105CH2	amidohydrolase
CO731_05510	ENOG4107QMS	site-determining protein
CO731_05512	ENOG4105F9F	transposase
CO731_05516	ENOG4108M0I	Transcriptional regulator
CO731_05518	ENOG4108JQ1	Dehydrogenase
CO731_05520	ENOG4105C5R	Aminotransferase
CO731_05522	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CO731_05524	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CO731_05527	ENOG4108JQ9	ABC transporter
CO731_05536	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CO731_05537	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CO731_05540	ENOG4107SQD	Transcriptional regulator, GntR family
CO731_05542	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CO731_05545	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
CO731_05548	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
CO731_05550	ENOG4105C32	Amino acid ABC transporter (Permease)
CO731_05551	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CO731_05552	ENOG4105C0Z	ABC transporter
CO731_05553	ENOG4108IV0	ABC, transporter
CO731_05555	ENOG4105C7J	ABC transporter, permease
CO731_05556	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CO731_05558	ENOG4108PVQ	transcriptional regulator
CO731_05559	ENOG4105C7B	Threonine dehydratase
CO731_05562	ENOG4105DTD	Dehydrogenase
CO731_05563	ENOG4108UKI	Enoyl-CoA hydratase
CO731_05564	ENOG4105C1G	acyl-Coa dehydrogenase
CO731_05567	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CO731_05569	ENOG4106IQC	argininosuccinate lyase
CO731_05570	ENOG4105DRS	transport system, permease
CO731_05571	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
CO731_05572	ENOG4107FKK	extracellular solute-binding protein family 1
CO731_05573	ENOG4105E2R	ROK family
CO731_05576	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CO731_05577	ENOG4106FTQ	Taurine ABC transporter, periplasmic
CO731_05579	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CO731_05584	ENOG4108E94	phosphate acetyltransferase
CO731_05586	ENOG4105C54	Major Facilitator superfamily
CO731_05589	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CO731_05590	ENOG4105DUM	transcriptional regulator, lysR family
CO731_05591	ENOG4105C28	cystathionine
CO731_05593	ENOG4108JEH	abc transporter atp-binding protein
CO731_05594	ENOG4105EAD	ABC transporter
CO731_05599	ENOG4108NDG	TRAP dicarboxylate
CO731_05601	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CO731_05602	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CO731_05604	ENOG4108RXX	maleylacetoacetate isomerase
CO731_05607	ENOG4105ERH	Fumarylacetoacetate hydrolase
CO731_05610	ENOG4105DC8	reductase
CO731_05612	ENOG4105DC8	reductase
CO731_05614	ENOG4105DC8	reductase
CO731_05616	ENOG4105DC8	reductase
CO731_05620	ENOG4105EQR	Transposase IS116 IS110 IS902
CO731_05622A	ENOG4105DFP	Integrase
CO731_05623	ENOG4105EN6	Membrane
CO731_05644	ENOG4105YES	addiction module antidote protein
CO731_05645	ENOG4105VUH	addiction module killer protein
CO731_05649	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CO731_05684	ENOG4105CEY	Amp-dependent synthetase and ligase