locus-tag	class	description
N7E70_000015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7E70_000040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_000050	COG0735	belongs to the Fur family
N7E70_000055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7E70_000065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N7E70_000070	COG3300	MHYT domain
N7E70_000070	COG5001	Diguanylate cyclase
N7E70_000075	COG2813	Specifically methylates the guanine in position
N7E70_000085	COG1185	polyribonucleotide nucleotidyltransferase activity
N7E70_000090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N7E70_000095	COG0598	Magnesium transport protein CorA
N7E70_000100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N7E70_000105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N7E70_000110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N7E70_000125	COG0779	Required for maturation of 30S ribosomal subunits
N7E70_000165	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N7E70_000170	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N7E70_000175	COG1396	sequence-specific DNA binding
N7E70_000180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
N7E70_000185	COG1253	flavin adenine dinucleotide binding
N7E70_000190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N7E70_000195	COG1702	phosphate starvation-inducible protein PhoH
N7E70_000200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7E70_000220	COG1214	PFAM Peptidase M22, glycoprotease
N7E70_000225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_000260	COG0481	GTPase activity
N7E70_000280	COG3220	belongs to the UPF0276 family
N7E70_000325	COG0671	phosphoesterase, PA-phosphatase related
N7E70_000335	COG0659	secondary active sulfate transmembrane transporter activity
N7E70_000340	COG0443	Heat shock 70 kDa protein
N7E70_000355	COG2358	TRAP transporter, solute receptor (TAXI family
N7E70_000375	COG3795	YCII-related domain
N7E70_000390	COG0640	Transcriptional regulator
N7E70_000425	COG0842	Transport permease protein
N7E70_000430	COG1131	(ABC) transporter
N7E70_000445	COG2954	triphosphatase activity
N7E70_000465	COG1420	regulation of RNA biosynthetic process
N7E70_000470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N7E70_000480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N7E70_000485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7E70_000505	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N7E70_000510	COG0792	nuclease activity
N7E70_000520	COG1254	Belongs to the acylphosphatase family
N7E70_000525	COG2124	cytochrome p450
N7E70_000555	COG0745	RESPONSE REGULATOR receiver
N7E70_000560	COG2205	protein histidine kinase activity
N7E70_000565	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
N7E70_000570	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N7E70_000575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N7E70_000600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N7E70_000605	COG2226	methyltransferase
N7E70_000610	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N7E70_000615	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N7E70_000635	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N7E70_000650	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_000660	COG3845	ABC transporter
N7E70_000665	COG2900	Belongs to the SlyX family
N7E70_000675	COG1744	ABC transporter substrate-binding protein PnrA-like
N7E70_000680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_000730	COG1477	protein flavinylation
N7E70_000745	COG1136	(ABC) transporter
N7E70_000765	COG1278	Cold shock
N7E70_000800	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_000830	COG0251	oxidation-reduction process
N7E70_000845	COG0662	Cupin 2, conserved barrel domain protein
N7E70_000855	COG0848	biopolymer transport protein
N7E70_000905	COG1082	Xylose isomerase domain protein TIM barrel
N7E70_000910	COG4607	ABC-type enterochelin transport system periplasmic component
N7E70_000915	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_000920	COG4605	iron ion homeostasis
N7E70_000925	COG4604	ABC transporter, ATP-binding protein
N7E70_000930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7E70_000935	COG4638	Rieske (2fe-2S)
N7E70_000970	COG4771	TonB-dependent receptor
N7E70_000975	COG4178	(ABC) transporter
N7E70_000995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N7E70_001000	COG0459	protein refolding
N7E70_001040	COG0395	ABC-type sugar transport system, permease component
N7E70_001045	COG1175	transmembrane transport
N7E70_001060	COG1765	OsmC-like protein
N7E70_001065	COG2766	serine protein kinase
N7E70_001070	COG2718	Belongs to the UPF0229 family
N7E70_001075	COG2719	SpoVR family
N7E70_001080	COG3142	Participates in the control of copper homeostasis
N7E70_001085	COG1940	carbohydrate kinase activity
N7E70_001100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_001105	COG1446	asparaginase
N7E70_001115	COG0765	amino acid transport
N7E70_001120	COG0765	amino acid transport
N7E70_001155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7E70_001190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_001195	COG1280	lysine exporter protein (LysE YggA)
N7E70_001200	COG1957	nucleoside hydrolase
N7E70_001215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_001220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N7E70_001225	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N7E70_001230	COG1137	ATPase activity
N7E70_001235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N7E70_001245	COG0616	signal peptide processing
N7E70_001250	COG0776	regulation of translation
N7E70_001260	COG2423	ornithine cyclodeaminase activity
N7E70_001275	COG2378	regulation of single-species biofilm formation
N7E70_001280	COG0116	Belongs to the methyltransferase superfamily
N7E70_001280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N7E70_001285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7E70_001290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N7E70_001300	COG0784	Response regulator, receiver
N7E70_001300	COG2205	protein histidine kinase activity
N7E70_001300	COG5002	protein histidine kinase activity
N7E70_001325	COG1252	NADH dehydrogenase
N7E70_001330	COG2860	membrane
N7E70_001335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N7E70_001350	COG0175	sulfate reduction
N7E70_001355	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7E70_001365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7E70_001365	COG1648	precorrin-2 dehydrogenase activity
N7E70_001375	COG4651	solute:proton antiporter activity
N7E70_001375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7E70_001395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N7E70_001400	COG2131	deaminase
N7E70_001450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7E70_001455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_001460	COG1942	4-Oxalocrotonate Tautomerase
N7E70_001480	COG1733	regulation of RNA biosynthetic process
N7E70_001490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7E70_001490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7E70_001505	COG0667	Aldo Keto reductase
N7E70_001510	COG0673	inositol 2-dehydrogenase activity
N7E70_001525	COG0395	ABC-type sugar transport system, permease component
N7E70_001530	COG1175	transmembrane transport
N7E70_001545	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N7E70_001555	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7E70_001560	COG1121	(ABC) transporter
N7E70_001565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7E70_001570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7E70_001575	COG3842	ATPase activity
N7E70_001580	COG0366	Alpha amylase catalytic
N7E70_001585	COG0395	ABC-type sugar transport system, permease component
N7E70_001590	COG1175	transmembrane transport
N7E70_001595	COG1653	transport
N7E70_001600	COG1609	Transcriptional regulator
N7E70_001605	COG1802	Transcriptional regulator
N7E70_001610	COG2272	Belongs to the type-B carboxylesterase lipase family
N7E70_001615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7E70_001615	COG0543	2 iron, 2 sulfur cluster binding
N7E70_001630	COG1595	DNA-templated transcription, initiation
N7E70_001640	COG1404	Belongs to the peptidase S8 family
N7E70_001660	COG3811	Belongs to the UPF0386 family
N7E70_001675	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_001710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_001720	COG0154	amidase activity
N7E70_001725	COG0747	negative chemotaxis
N7E70_001730	COG0601	transmembrane transport
N7E70_001735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_001760	COG0625	glutathione transferase activity
N7E70_001850	COG1072	(Pantothenic acid kinase))
N7E70_001855	COG0625	glutathione transferase activity
N7E70_001870	COG0829	nickel cation binding
N7E70_001880	COG3813	Protein conserved in bacteria
N7E70_001890	COG0832	Belongs to the urease beta subunit family
N7E70_001915	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
N7E70_001920	COG0830	nickel cation binding
N7E70_001930	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N7E70_001940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_001955	COG0534	Mate efflux family protein
N7E70_001970	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_001975	COG3842	ATPase activity
N7E70_001985	COG0765	amino acid transport
N7E70_001990	COG0765	amino acid transport
N7E70_002005	COG0583	DNA-binding transcription factor activity
N7E70_002010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N7E70_002035	COG1129	ABC transporter
N7E70_002050	COG1335	isochorismatase
N7E70_002080	COG1846	Transcriptional regulator
N7E70_002085	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_002090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N7E70_002115	COG0673	inositol 2-dehydrogenase activity
N7E70_002120	COG0395	ABC-type sugar transport system, permease component
N7E70_002135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N7E70_002140	COG2971	BadF BadG BcrA BcrD
N7E70_002145	COG2188	Transcriptional regulator
N7E70_002155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N7E70_002180	COG1879	ABC-type sugar transport system periplasmic component
N7E70_002190	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_002200	COG1609	Transcriptional regulator
N7E70_002210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_002220	COG4941	Belongs to the sigma-70 factor family
N7E70_002225	COG3795	YCII-related domain
N7E70_002230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7E70_002280	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
N7E70_002285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N7E70_002290	COG4335	DNA alkylation repair
N7E70_002310	COG0121	glutamine amidotransferase
N7E70_002320	COG1522	sequence-specific DNA binding
N7E70_002325	COG0756	dUTP diphosphatase activity
N7E70_002330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_002335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N7E70_002345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_002350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N7E70_002360	COG0280	phosphate acetyltransferase
N7E70_002360	COG0281	malic enzyme
N7E70_002365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N7E70_002395	COG0596	Alpha beta hydrolase
N7E70_002410	COG0662	Cupin 2, conserved barrel domain protein
N7E70_002410	COG2207	Transcriptional regulator
N7E70_002445	COG5001	Diguanylate cyclase
N7E70_002445	COG5002	protein histidine kinase activity
N7E70_002455	COG0656	L-ascorbic acid biosynthetic process
N7E70_002475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
N7E70_002480	COG0728	peptidoglycan biosynthetic process
N7E70_002495	COG0463	Glycosyl transferase, family 2
N7E70_002495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7E70_002500	COG0180	Tryptophanyl-tRNA synthetase
N7E70_002510	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N7E70_002515	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_002525	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
N7E70_002535	COG1643	Atp-dependent helicase
N7E70_002545	COG0673	inositol 2-dehydrogenase activity
N7E70_002550	COG1737	Transcriptional regulator
N7E70_002555	COG0129	dihydroxy-acid dehydratase activity
N7E70_002570	COG0626	cystathionine gamma-synthase activity
N7E70_002575	COG1846	Transcriptional regulator
N7E70_002580	COG0697	spore germination
N7E70_002600	COG1116	anion transmembrane transporter activity
N7E70_002620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_002640	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_002650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7E70_002655	COG1802	Transcriptional regulator
N7E70_002660	COG0579	oxidoreductase
N7E70_002670	COG1522	sequence-specific DNA binding
N7E70_002675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7E70_002680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_002685	COG2186	Transcriptional regulator
N7E70_002690	COG0626	cystathionine gamma-synthase activity
N7E70_002705	COG0395	ABC-type sugar transport system, permease component
N7E70_002710	COG3842	ATPase activity
N7E70_002715	COG0840	transmembrane signaling receptor activity
N7E70_002725	COG0745	RESPONSE REGULATOR receiver
N7E70_002730	COG2198	Histidine kinase
N7E70_002730	COG0643	Histidine kinase
N7E70_002735	COG0835	chemotaxis
N7E70_002740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N7E70_002745	COG2201	protein-glutamate methylesterase activity
N7E70_002750	COG0745	RESPONSE REGULATOR receiver
N7E70_002755	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N7E70_002815	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_002820	COG1063	alcohol dehydrogenase
N7E70_002830	COG4608	Belongs to the ABC transporter superfamily
N7E70_002840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_002845	COG0601	transmembrane transport
N7E70_002860	COG2186	Transcriptional regulator
N7E70_002875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_002880	COG0346	lactoylglutathione lyase activity
N7E70_002885	COG0346	lactoylglutathione lyase activity
N7E70_002895	COG2124	cytochrome p450
N7E70_002920	COG1846	Transcriptional regulator
N7E70_002925	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
N7E70_002940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_002975	COG0436	Aminotransferase
N7E70_002990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_002995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7E70_003000	COG1473	amidohydrolase
N7E70_003005	COG1957	nucleoside hydrolase
N7E70_003010	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7E70_003020	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_003025	COG3842	ATPase activity
N7E70_003030	COG1177	transmembrane transport
N7E70_003035	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_003055	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_003065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_003070	COG0601	transmembrane transport
N7E70_003090	COG4172	Belongs to the ABC transporter superfamily
N7E70_003110	COG0747	negative chemotaxis
N7E70_003140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N7E70_003145	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_003150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N7E70_003155	COG0539	negative regulation of cytoplasmic translation
N7E70_003175	COG1309	transcriptional regulator
N7E70_003185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_003190	COG4215	(ABC) transporter
N7E70_003200	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_003230	COG1968	undecaprenyl-diphosphatase activity
N7E70_003240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N7E70_003250	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
N7E70_003255	COG1803	Methylglyoxal synthase
N7E70_003260	COG0837	glucose binding
N7E70_003265	COG1132	(ABC) transporter
N7E70_003270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N7E70_003275	COG0588	phosphoglycerate mutase activity
N7E70_003315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N7E70_003325	COG3386	PFAM SMP-30 Gluconolaconase
N7E70_003330	COG0800	Aldolase
N7E70_003335	COG3734	2-keto-3-deoxy-galactonokinase
N7E70_003340	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_003345	COG5001	Diguanylate cyclase
N7E70_003355	COG1309	transcriptional regulator
N7E70_003360	COG0189	ligase activity
N7E70_003375	COG5001	Diguanylate cyclase
N7E70_003375	COG3447	MASE1 domain protein
N7E70_003375	COG5002	protein histidine kinase activity
N7E70_003400	COG0284	orotidine-5'-phosphate decarboxylase activity
N7E70_003410	COG3963	phosphatidate phosphatase activity
N7E70_003415	COG0484	heat shock protein binding
N7E70_003425	COG0443	Heat shock 70 kDa protein
N7E70_003455	COG3038	cytochrome b561
N7E70_003465	COG0072	phenylalanine-tRNA ligase activity
N7E70_003465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7E70_003475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N7E70_003480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N7E70_003485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N7E70_003495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N7E70_003505	COG3135	benzoate transporter
N7E70_003520	COG0583	DNA-binding transcription factor activity
N7E70_003525	COG0135	phosphoribosylanthranilate isomerase activity
N7E70_003530	COG0133	tryptophan synthase activity
N7E70_003535	COG0159	tryptophan synthase activity
N7E70_003540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N7E70_003555	COG1074	ATP-dependent DNA helicase activity
N7E70_003565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N7E70_003570	COG3178	'Phosphotransferase
N7E70_003575	COG2205	protein histidine kinase activity
N7E70_003580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N7E70_003585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_003590	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_003590	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7E70_003600	COG2205	protein histidine kinase activity
N7E70_003605	COG0745	RESPONSE REGULATOR receiver
N7E70_003610	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N7E70_003620	COG1652	LysM domain
N7E70_003630	COG1072	(Pantothenic acid kinase))
N7E70_003635	COG0140	phosphoribosyl-ATP diphosphatase activity
N7E70_003645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N7E70_003655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7E70_003665	COG0131	Imidazoleglycerol-phosphate dehydratase
N7E70_003670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N7E70_003690	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N7E70_003700	COG3800	Transcriptional regulator
N7E70_003700	COG1396	sequence-specific DNA binding
N7E70_003720	COG3030	protein affecting phage T7 exclusion by the F plasmid
N7E70_003725	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
N7E70_003735	COG0237	dephospho-CoA kinase activity
N7E70_003740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N7E70_003745	COG0424	maF-like protein
N7E70_003750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N7E70_003755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N7E70_003760	COG1981	membrane
N7E70_003765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N7E70_003770	COG1331	Highly conserved protein containing a thioredoxin domain
N7E70_003775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N7E70_003780	COG0445	tRNA wobble uridine modification
N7E70_003785	COG0357	Ribosomal RNA small subunit methyltransferase G
N7E70_003855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7E70_003865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N7E70_003865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N7E70_003875	COG4770	biotin carboxylase activity
N7E70_003880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7E70_003890	COG1396	sequence-specific DNA binding
N7E70_003890	COG3800	Transcriptional regulator
N7E70_003900	COG2183	response to ionizing radiation
N7E70_003905	COG0137	argininosuccinate synthase activity
N7E70_003935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N7E70_003940	COG1605	Chorismate mutase
N7E70_003940	COG0287	Prephenate dehydrogenase
N7E70_003945	COG0228	four-way junction DNA binding
N7E70_003950	COG5001	Diguanylate cyclase
N7E70_003965	COG3781	membrane
N7E70_003975	COG0454	-acetyltransferase
N7E70_003980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N7E70_004000	COG4178	(ABC) transporter
N7E70_004005	COG3152	Membrane
N7E70_004010	COG0473	3-isopropylmalate dehydrogenase activity
N7E70_004020	COG0251	oxidation-reduction process
N7E70_004030	COG0066	3-isopropylmalate dehydratase activity
N7E70_004040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7E70_004045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_004050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_004055	COG1120	ATPase activity
N7E70_004060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7E70_004070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_004075	COG0525	valine-tRNA ligase activity
N7E70_004080	COG0765	amino acid transport
N7E70_004085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_004100	COG2814	Major facilitator Superfamily
N7E70_004130	COG1595	DNA-templated transcription, initiation
N7E70_004165	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7E70_004180	COG2301	Belongs to the HpcH HpaI aldolase family
N7E70_004205	COG0587	DNA-directed DNA polymerase activity
N7E70_004210	COG2835	tetraacyldisaccharide 4'-kinase activity
N7E70_004215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N7E70_004220	COG3118	belongs to the thioredoxin family
N7E70_004240	COG0010	Belongs to the arginase family
N7E70_004245	COG0436	Aminotransferase
N7E70_004265	COG0463	Glycosyl transferase, family 2
N7E70_004270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7E70_004275	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_004280	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_004285	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7E70_004295	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_004310	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_004320	COG4154	Belongs to the RbsD FucU family
N7E70_004325	COG4608	Belongs to the ABC transporter superfamily
N7E70_004330	COG0444	Belongs to the ABC transporter superfamily
N7E70_004335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_004340	COG0601	transmembrane transport
N7E70_004345	COG0747	negative chemotaxis
N7E70_004355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7E70_004370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N7E70_004390	COG3339	Conserved Protein
N7E70_004395	COG2154	pterin-4-alpha-carbinolamine dehydratase
N7E70_004400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7E70_004415	COG1136	(ABC) transporter
N7E70_004420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
N7E70_004425	COG0670	Belongs to the BI1 family
N7E70_004435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N7E70_004440	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_004460	COG2372	response to copper ion
N7E70_004460	COG1276	copper resistance
N7E70_004480	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_004485	COG5001	Diguanylate cyclase
N7E70_004485	COG3300	MHYT domain
N7E70_004520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N7E70_004530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N7E70_004535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7E70_004540	COG0552	protein localization to endoplasmic reticulum
N7E70_004545	COG2917	probably involved in intracellular septation
N7E70_004555	COG0431	NADPH-dependent FMN reductase
N7E70_004570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7E70_004580	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7E70_004585	COG4133	protoheme IX ABC transporter activity
N7E70_004590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N7E70_004605	COG0039	L-malate dehydrogenase activity
N7E70_004610	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_004615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N7E70_004620	COG0567	Dehydrogenase, E1 component
N7E70_004625	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_004640	COG1280	lysine exporter protein (LysE YggA)
N7E70_004650	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_004680	COG4974	Belongs to the 'phage' integrase family
N7E70_004685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N7E70_004705	COG0335	large ribosomal subunit rRNA binding
N7E70_004710	COG0456	acetyltransferase
N7E70_004730	COG0765	amino acid transport
N7E70_004765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N7E70_004780	COG2009	succinate dehydrogenase
N7E70_004810	COG3132	Protein of unknown function, DUF480
N7E70_004830	COG1764	response to oxidative stress
N7E70_004835	COG3795	YCII-related domain
N7E70_004840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_004845	COG1946	Acyl-CoA thioesterase
N7E70_004850	COG0347	Belongs to the P(II) protein family
N7E70_004855	COG0004	ammonium transporteR
N7E70_004875	COG1674	ftsk spoiiie
N7E70_004875	COG2261	transglycosylase associated protein
N7E70_004880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N7E70_004895	COG0745	RESPONSE REGULATOR receiver
N7E70_004910	COG0583	DNA-binding transcription factor activity
N7E70_004915	COG2264	protein methyltransferase activity
N7E70_004930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N7E70_004935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N7E70_004940	COG0181	hydroxymethylbilane synthase activity
N7E70_004965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7E70_004990	COG3307	-O-antigen
N7E70_004995	COG1596	polysaccharide export
N7E70_005025	COG2273	Hydrolase Family 16
N7E70_005060	COG1215	transferase activity, transferring glycosyl groups
N7E70_005065	COG1215	transferase activity, transferring glycosyl groups
N7E70_005070	COG1215	transferase activity, transferring glycosyl groups
N7E70_005075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7E70_005080	COG0489	protein tyrosine kinase activity
N7E70_005080	COG3206	protein involved in exopolysaccharide biosynthesis
N7E70_005085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7E70_005095	COG3920	Histidine kinase
N7E70_005100	COG2755	lipolytic protein G-D-S-L family
N7E70_005100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N7E70_005110	COG3239	Fatty acid desaturase
N7E70_005130	COG3284	Transcriptional regulator
N7E70_005155	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_005165	COG3119	arylsulfatase activity
N7E70_005185	COG1940	carbohydrate kinase activity
N7E70_005190	COG0730	response to heat
N7E70_005195	COG1879	ABC-type sugar transport system periplasmic component
N7E70_005200	COG1802	Transcriptional regulator
N7E70_005205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_005220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_005230	COG0778	Nitroreductase
N7E70_005240	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7E70_005255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_005270	COG0840	transmembrane signaling receptor activity
N7E70_005270	COG2972	Histidine kinase
N7E70_005280	COG0601	transmembrane transport
N7E70_005285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_005295	COG1228	amidohydrolase
N7E70_005300	COG0444	Belongs to the ABC transporter superfamily
N7E70_005305	COG4608	Belongs to the ABC transporter superfamily
N7E70_005310	COG1802	Transcriptional regulator
N7E70_005315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_005325	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_005330	COG0747	negative chemotaxis
N7E70_005335	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_005340	COG0583	DNA-binding transcription factor activity
N7E70_005345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_005350	COG0765	amino acid transport
N7E70_005360	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_005375	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_005380	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_005440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_005450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7E70_005465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_005470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7E70_005505	COG1872	DUF167
N7E70_005515	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N7E70_005535	COG1704	LemA family
N7E70_005565	COG2814	Major facilitator Superfamily
N7E70_005570	COG1846	Transcriptional regulator
N7E70_005575	COG0339	signal peptide processing
N7E70_005585	COG1217	gtp-binding protein TYPA
N7E70_005605	COG2270	Major facilitator Superfamily
N7E70_005610	COG0138	bifunctional purine biosynthesis protein purh
N7E70_005620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N7E70_005620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7E70_005625	COG0501	Belongs to the peptidase M48B family
N7E70_005650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7E70_005655	COG0789	Transcriptional regulator
N7E70_005665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7E70_005670	COG5425	PFAM Usg family protein
N7E70_005685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N7E70_005690	COG0495	leucyl-tRNA aminoacylation
N7E70_005700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7E70_005710	COG1522	sequence-specific DNA binding
N7E70_005715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N7E70_005735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7E70_005745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N7E70_005750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N7E70_005755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N7E70_005760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7E70_005765	COG0590	tRNA wobble adenosine to inosine editing
N7E70_005780	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N7E70_005790	COG1091	dTDP-4-dehydrorhamnose reductase activity
N7E70_005800	COG3754	Rhamnan synthesis protein F
N7E70_005825	COG3743	rRNA binding
N7E70_005825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N7E70_005830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N7E70_005845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N7E70_005850	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7E70_005855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N7E70_005860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N7E70_005875	COG0799	negative regulation of ribosome biogenesis
N7E70_005880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N7E70_005900	COG0793	Belongs to the peptidase S41A family
N7E70_005910	COG0494	nUDIX hydrolase
N7E70_005915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_005925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_005950	COG3655	Transcriptional regulator
N7E70_005975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_005980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_006020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N7E70_006030	COG2223	nitrite transmembrane transporter activity
N7E70_006035	COG0583	DNA-binding transcription factor activity
N7E70_006055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7E70_006070	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_006080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N7E70_006085	COG0741	lytic transglycosylase activity
N7E70_006090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7E70_006110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7E70_006115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N7E70_006130	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
N7E70_006135	COG0183	Belongs to the thiolase family
N7E70_006140	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_006145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N7E70_006160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N7E70_006165	COG1329	Transcriptional regulator
N7E70_006180	COG1126	abc transporter atp-binding protein
N7E70_006185	COG0765	amino acid transport
N7E70_006190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_006205	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
N7E70_006225	COG0488	(ABC) transporter
N7E70_006240	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N7E70_006250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7E70_006255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N7E70_006285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7E70_006300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7E70_006305	COG0037	tRNA processing
N7E70_006315	COG2885	chlorophyll binding
N7E70_006330	COG0848	biopolymer transport protein
N7E70_006340	COG0824	Thioesterase
N7E70_006345	COG2226	methyltransferase
N7E70_006365	COG2255	four-way junction helicase activity
N7E70_006390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
N7E70_006410	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_006430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N7E70_006435	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_006440	COG1272	protein, Hemolysin III
N7E70_006490	COG1132	(ABC) transporter
N7E70_006495	COG0254	rRNA binding
N7E70_006520	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7E70_006530	COG0217	transcriptional regulatory protein
N7E70_006560	COG1733	regulation of RNA biosynthetic process
N7E70_006580	COG0305	Participates in initiation and elongation during chromosome replication
N7E70_006585	COG0861	Integral membrane protein TerC family
N7E70_006590	COG1692	metallophosphoesterase
N7E70_006595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7E70_006630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_006650	COG0583	DNA-binding transcription factor activity
N7E70_006655	COG0431	NADPH-dependent FMN reductase
N7E70_006660	COG3750	Belongs to the UPF0335 family
N7E70_006680	COG0469	pyruvate kinase activity
N7E70_006685	COG2267	carboxylic ester hydrolase activity
N7E70_006690	COG0457	Tetratricopeptide repeat
N7E70_006695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N7E70_006700	COG3755	Protein conserved in bacteria
N7E70_006705	COG1733	regulation of RNA biosynthetic process
N7E70_006715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N7E70_006735	COG0640	Transcriptional regulator
N7E70_006750	COG3321	synthase
N7E70_006750	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_006750	COG0604	alcohol dehydrogenase
N7E70_006755	COG2226	methyltransferase
N7E70_006765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_006775	COG0145	ligase activity
N7E70_006780	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
N7E70_006795	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_006810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7E70_006810	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_006810	COG1042	CoA-binding domain protein
N7E70_006820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_006825	COG0697	spore germination
N7E70_006840	COG0183	Belongs to the thiolase family
N7E70_006860	COG4191	Histidine kinase
N7E70_006890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_006905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_007060	COG3588	fructose-bisphosphate aldolase
N7E70_007070	COG0126	phosphoglycerate kinase activity
N7E70_007110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N7E70_007120	COG0564	pseudouridine synthase activity
N7E70_007130	COG0346	lactoylglutathione lyase activity
N7E70_007335	COG0573	inorganic phosphate transmembrane transporter activity
N7E70_007345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7E70_007350	COG0704	Plays a role in the regulation of phosphate uptake
N7E70_007355	COG0745	RESPONSE REGULATOR receiver
N7E70_007365	COG4213	ABC transporter substrate-binding protein
N7E70_007370	COG4214	carbohydrate transport
N7E70_007395	COG2202	Pas domain
N7E70_007395	COG3920	Histidine kinase
N7E70_007405	COG0784	Response regulator, receiver
N7E70_007420	COG0784	Response regulator, receiver
N7E70_007425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_007430	COG0628	permease
N7E70_007470	COG0346	lactoylglutathione lyase activity
N7E70_007475	COG0400	carboxylic ester hydrolase activity
N7E70_007495	COG2199	diguanylate cyclase activity
N7E70_007495	COG2200	EAL domain
N7E70_007495	COG2203	Gaf domain
N7E70_007500	COG0745	RESPONSE REGULATOR receiver
N7E70_007505	COG0745	RESPONSE REGULATOR receiver
N7E70_007520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7E70_007525	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
N7E70_007530	COG3833	ABC-type maltose transport systems, permease component
N7E70_007535	COG3842	ATPase activity
N7E70_007555	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_007560	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_007585	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_007595	COG3842	ATPase activity
N7E70_007600	COG1238	metal cluster binding
N7E70_007610	COG2132	Multicopper oxidase
N7E70_007645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7E70_007650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7E70_007660	COG1845	cytochrome c oxidase, subunit III
N7E70_007675	COG0406	alpha-ribazole phosphatase activity
N7E70_007680	COG3842	ATPase activity
N7E70_007685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N7E70_007705	COG1737	Transcriptional regulator
N7E70_007715	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_007730	COG0395	ABC-type sugar transport system, permease component
N7E70_007740	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_007745	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_007750	COG3845	ABC transporter
N7E70_007760	COG2186	Transcriptional regulator
N7E70_007780	COG0625	glutathione transferase activity
N7E70_007785	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N7E70_007790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N7E70_007795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7E70_007795	COG0352	thiamine-phosphate diphosphorylase activity
N7E70_007795	COG0351	phosphomethylpyrimidine kinase
N7E70_007805	COG2022	thiamine diphosphate biosynthetic process
N7E70_007820	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N7E70_007845	COG0356	it plays a direct role in the translocation of protons across the membrane
N7E70_007860	COG1473	amidohydrolase
N7E70_007865	COG1686	Belongs to the peptidase S11 family
N7E70_007870	COG0523	cobalamin synthesis protein
N7E70_007875	COG0425	Belongs to the sulfur carrier protein TusA family
N7E70_007885	COG0825	malonyl-CoA metabolic process
N7E70_007900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N7E70_007905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N7E70_007910	COG4536	flavin adenine dinucleotide binding
N7E70_007970	COG1522	sequence-specific DNA binding
N7E70_007995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N7E70_008000	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N7E70_008025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_008030	COG2226	methyltransferase
N7E70_008045	COG1597	lipid kinase activity
N7E70_008055	COG2814	Major facilitator Superfamily
N7E70_008060	COG0583	DNA-binding transcription factor activity
N7E70_008065	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N7E70_008070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N7E70_008075	COG0287	Prephenate dehydrogenase
N7E70_008090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7E70_008090	COG2169	Transcriptional regulator
N7E70_008115	COG2884	Cell division ATP-binding protein ftsE
N7E70_008125	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N7E70_008140	COG0583	DNA-binding transcription factor activity
N7E70_008150	COG0019	diaminopimelate decarboxylase activity
N7E70_008160	COG0165	Argininosuccinate lyase
N7E70_008165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7E70_008170	COG1653	transport
N7E70_008175	COG1175	transmembrane transport
N7E70_008180	COG0395	ABC-type sugar transport system, permease component
N7E70_008185	COG3842	ATPase activity
N7E70_008195	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_008200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N7E70_008205	COG2086	electron transfer activity
N7E70_008225	COG0300	oxidoreductase activity
N7E70_008235	COG0697	spore germination
N7E70_008245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7E70_008265	COG1238	metal cluster binding
N7E70_008295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7E70_008315	COG2239	Acts as a magnesium transporter
N7E70_008320	COG0653	protein targeting
N7E70_008325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7E70_008345	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N7E70_008350	COG0456	acetyltransferase
N7E70_008355	COG0494	nUDIX hydrolase
N7E70_008370	COG2226	methyltransferase
N7E70_008385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7E70_008410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_008415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_008420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N7E70_008425	COG0527	aspartate kinase activity
N7E70_008435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N7E70_008440	COG2890	protein-(glutamine-N5) methyltransferase activity
N7E70_008450	COG0542	response to heat
N7E70_008460	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_008485	COG0625	glutathione transferase activity
N7E70_008490	COG0477	Major facilitator Superfamily
N7E70_008495	COG0741	lytic transglycosylase activity
N7E70_008495	COG1196	nuclear chromosome segregation
N7E70_008495	COG0739	heme binding
N7E70_008665	COG2433	Pfam Transposase IS66
N7E70_008670	COG3436	PFAM IS66 Orf2 family protein
N7E70_008680	COG2433	Pfam Transposase IS66
N7E70_008685	COG3436	PFAM IS66 Orf2 family protein
N7E70_008715	COG0010	Belongs to the arginase family
N7E70_008755	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_008765	COG3842	ATPase activity
N7E70_008785	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_008785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_008805	COG0583	DNA-binding transcription factor activity
N7E70_008825	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_008830	COG3842	ATPase activity
N7E70_008840	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_008850	COG0583	DNA-binding transcription factor activity
N7E70_008885	COG0435	Glutathione S-transferase
N7E70_008925	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_008930	COG4175	Glycine betaine
N7E70_008930	COG3448	diguanylate cyclase activity
N7E70_008940	COG0745	RESPONSE REGULATOR receiver
N7E70_008945	COG2205	protein histidine kinase activity
N7E70_008955	COG0745	RESPONSE REGULATOR receiver
N7E70_008965	COG1879	ABC-type sugar transport system periplasmic component
N7E70_008970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_008975	COG3842	ATPase activity
N7E70_008995	COG1070	Carbohydrate kinase
N7E70_009005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N7E70_009010	COG0667	Aldo Keto reductase
N7E70_009020	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_009025	COG1129	ABC transporter
N7E70_009035	COG2358	TRAP transporter, solute receptor (TAXI family
N7E70_009045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_009055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_009095	COG0463	Glycosyl transferase, family 2
N7E70_009100	COG1215	transferase activity, transferring glycosyl groups
N7E70_009120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_009125	COG1120	ATPase activity
N7E70_009130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_009145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_009150	COG0205	6-phosphofructokinase activity
N7E70_009155	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_009155	COG1388	LysM domain
N7E70_009160	COG1280	lysine exporter protein (LysE YggA)
N7E70_009170	COG1070	Carbohydrate kinase
N7E70_009180	COG2115	Belongs to the xylose isomerase family
N7E70_009195	COG1011	Hydrolase
N7E70_009200	COG4977	sequence-specific DNA binding
N7E70_009205	COG3246	L-lysine catabolic process to acetate
N7E70_009210	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_009230	COG0657	acetylesterase activity
N7E70_009240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_009265	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
N7E70_009270	COG3257	ureidoglycine aminohydrolase activity
N7E70_009280	COG2351	hydroxyisourate hydrolase activity
N7E70_009290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N7E70_009300	COG0783	Belongs to the Dps family
N7E70_009315	COG0583	DNA-binding transcription factor activity
N7E70_009325	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_009330	COG4702	Belongs to the UPF0303 family
N7E70_009350	COG0174	glutamine synthetase
N7E70_009380	COG0523	cobalamin synthesis protein
N7E70_009390	COG1846	Transcriptional regulator
N7E70_009405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_009420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
N7E70_009425	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N7E70_009430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N7E70_009445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_009445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N7E70_009475	COG5001	Diguanylate cyclase
N7E70_009515	COG1280	lysine exporter protein (LysE YggA)
N7E70_009525	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7E70_009535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
N7E70_009555	COG2223	nitrite transmembrane transporter activity
N7E70_009570	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_009580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_009600	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_009600	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_009660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
N7E70_009700	COG0583	DNA-binding transcription factor activity
N7E70_009705	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N7E70_009710	COG3842	ATPase activity
N7E70_009715	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_009720	COG1177	transmembrane transport
N7E70_009725	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_009740	COG1609	Transcriptional regulator
N7E70_009755	COG1024	Enoyl-CoA hydratase
N7E70_009760	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_009765	COG1653	transport
N7E70_009775	COG0395	ABC-type sugar transport system, permease component
N7E70_009780	COG3842	ATPase activity
N7E70_009790	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_009800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7E70_009805	COG3774	pathogenesis
N7E70_009810	COG4608	Belongs to the ABC transporter superfamily
N7E70_009815	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_009820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_009830	COG4533	DNA binding
N7E70_009835	COG0444	Belongs to the ABC transporter superfamily
N7E70_009865	COG2072	flavoprotein involved in K transport
N7E70_009895	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_009905	COG0067	glutamate synthase
N7E70_009905	COG0069	glutamate synthase activity
N7E70_009905	COG0070	glutamate synthase
N7E70_009920	COG2951	lytic endotransglycosylase activity
N7E70_009925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7E70_009930	COG0778	Nitroreductase
N7E70_009955	COG1585	Membrane protein implicated in regulation of membrane protease activity
N7E70_009960	COG0330	HflC and HflK could
N7E70_009965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
N7E70_009965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_009970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N7E70_009975	COG0737	Belongs to the 5'-nucleotidase family
N7E70_009985	COG3775	system Galactitol-specific IIC component
N7E70_010000	COG5310	Homospermidine synthase
N7E70_010035	COG2204	response regulator
N7E70_010040	COG3108	Peptidase M15
N7E70_010045	COG0800	Aldolase
N7E70_010055	COG1054	Belongs to the UPF0176 family
N7E70_010065	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_010120	COG0583	DNA-binding transcription factor activity
N7E70_010125	COG0154	amidase activity
N7E70_010175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7E70_010180	COG2814	Major facilitator Superfamily
N7E70_010190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N7E70_010195	COG5443	negative regulation of bacterial-type flagellum assembly
N7E70_010200	COG5442	Flagellar protein FlaF
N7E70_010215	COG1749	Flagellar hook protein flgE
N7E70_010255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_010260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_010265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_010275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7E70_010280	COG1338	Plays a role in the flagellum-specific transport system
N7E70_010290	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
N7E70_010300	COG1706	bacterial-type flagellum-dependent cell motility
N7E70_010305	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
N7E70_010310	COG4786	Flagellar basal body rod
N7E70_010315	COG1677	Flagellar hook-basal body complex protein FliE
N7E70_010320	COG1558	bacterial-type flagellum-dependent cell motility
N7E70_010325	COG1815	bacterial-type flagellum-dependent cell motility
N7E70_010335	COG1157	protein secretion by the type III secretion system
N7E70_010340	COG4786	Flagellar basal body rod
N7E70_010350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N7E70_010360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7E70_010365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7E70_010370	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7E70_010385	COG2771	luxR family
N7E70_010400	COG1309	transcriptional regulator
N7E70_010405	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N7E70_010410	COG3842	ATPase activity
N7E70_010420	COG1177	transmembrane transport
N7E70_010450	COG4213	ABC transporter substrate-binding protein
N7E70_010455	COG1129	ABC transporter
N7E70_010460	COG4214	carbohydrate transport
N7E70_010510	COG1129	ABC transporter
N7E70_010515	COG4211	Belongs to the binding-protein-dependent transport system permease family
N7E70_010520	COG0673	inositol 2-dehydrogenase activity
N7E70_010525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_010530	COG3962	Belongs to the TPP enzyme family
N7E70_010535	COG1082	Xylose isomerase domain protein TIM barrel
N7E70_010545	COG3718	enzyme involved in inositol metabolism
N7E70_010550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7E70_010580	COG2197	response regulator
N7E70_010600	COG0747	negative chemotaxis
N7E70_010625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_010630	COG0747	negative chemotaxis
N7E70_010645	COG3454	Phosphonate metabolism
N7E70_010650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
N7E70_010655	COG3639	organic phosphonate transmembrane transporter activity
N7E70_010670	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
N7E70_010675	COG1733	regulation of RNA biosynthetic process
N7E70_010690	COG0786	glutamate:sodium symporter activity
N7E70_010700	COG4778	phosphonate C-P lyase system protein PhnL
N7E70_010705	COG4107	phosphonate C-P lyase system protein PhnK
N7E70_010710	COG3627	carbon phosphorus lyase activity
N7E70_010715	COG3626	phosphonate metabolism
N7E70_010720	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
N7E70_010725	COG3624	Phosphonate C-P lyase system protein PhnG
N7E70_010730	COG2188	Transcriptional regulator
N7E70_010745	COG1177	transmembrane transport
N7E70_010755	COG2072	flavoprotein involved in K transport
N7E70_010770	COG3620	sequence-specific DNA binding
N7E70_010800	COG0583	DNA-binding transcription factor activity
N7E70_010810	COG3842	ATPase activity
N7E70_010820	COG1175	transmembrane transport
N7E70_010845	COG1192	Involved in chromosome partitioning
N7E70_010855	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
N7E70_010860	COG0322	excinuclease ABC activity
N7E70_010865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
N7E70_010940	COG0482	sulfurtransferase activity
N7E70_010955	COG0604	alcohol dehydrogenase
N7E70_010960	COG1733	regulation of RNA biosynthetic process
N7E70_010975	COG2201	protein-glutamate methylesterase activity
N7E70_011020	COG0435	Glutathione S-transferase
N7E70_011025	COG0494	nUDIX hydrolase
N7E70_011040	COG0596	Alpha beta hydrolase
N7E70_011040	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_011050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7E70_011060	COG3180	Ammonia monooxygenase
N7E70_011090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7E70_011090	COG0512	Glutamine amidotransferase of anthranilate synthase
N7E70_011095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_011105	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
N7E70_011110	COG2814	Major facilitator Superfamily
N7E70_011115	COG0583	DNA-binding transcription factor activity
N7E70_011120	COG4993	Dehydrogenase
N7E70_011130	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N7E70_011150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N7E70_011185	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N7E70_011215	COG1435	thymidine kinase activity
N7E70_011225	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_011230	COG3448	diguanylate cyclase activity
N7E70_011230	COG4175	Glycine betaine
N7E70_011250	COG5507	3-demethylubiquinone-9 3-methyltransferase
N7E70_011255	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N7E70_011280	COG1278	Cold shock
N7E70_011305	COG0714	Associated with various cellular activities
N7E70_011315	COG0494	nUDIX hydrolase
N7E70_011320	COG0617	tRNA 3'-terminal CCA addition
N7E70_011340	COG0408	coproporphyrinogen oxidase activity
N7E70_011370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N7E70_011380	COG1132	(ABC) transporter
N7E70_011385	COG1132	(ABC) transporter
N7E70_011390	COG1132	(ABC) transporter
N7E70_011410	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7E70_011410	COG2857	Cytochrome c1
N7E70_011415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7E70_011445	COG0012	GTP binding
N7E70_011450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7E70_011465	COG0193	aminoacyl-tRNA hydrolase activity
N7E70_011470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N7E70_011490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N7E70_011505	COG1496	oxidoreductase activity
N7E70_011515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N7E70_011530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7E70_011540	COG1464	Belongs to the NlpA lipoprotein family
N7E70_011545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N7E70_011550	COG2011	ABC-type metal ion transport system permease component
N7E70_011555	COG2205	protein histidine kinase activity
N7E70_011565	COG0745	RESPONSE REGULATOR receiver
N7E70_011570	COG1846	Transcriptional regulator
N7E70_011575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_011585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_011595	COG1278	Cold shock
N7E70_011605	COG1278	Cold shock
N7E70_011625	COG0583	DNA-binding transcription factor activity
N7E70_011640	COG1819	glycosyl
N7E70_011645	COG1309	transcriptional regulator
N7E70_011650	COG1794	racemase activity, acting on amino acids and derivatives
N7E70_011660	COG3791	Glutathione-dependent formaldehyde-activating
N7E70_011670	COG0726	polysaccharide deacetylase
N7E70_011690	COG1396	sequence-specific DNA binding
N7E70_011720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_011730	COG1522	sequence-specific DNA binding
N7E70_011745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_011760	COG0583	DNA-binding transcription factor activity
N7E70_011775	COG0556	nucleotide-excision repair
N7E70_011785	COG0438	transferase activity, transferring glycosyl groups
N7E70_011815	COG1597	lipid kinase activity
N7E70_011835	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_011865	COG1253	flavin adenine dinucleotide binding
N7E70_011910	COG0583	DNA-binding transcription factor activity
N7E70_011920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_011935	COG2133	pyrroloquinoline quinone binding
N7E70_011940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_011955	COG3306	glycosyltransferase involved in LPS biosynthesis
N7E70_011960	COG3306	glycosyltransferase involved in LPS biosynthesis
N7E70_011970	COG1522	sequence-specific DNA binding
N7E70_011975	COG0492	ferredoxin-NADP+ reductase activity
N7E70_011980	COG0583	DNA-binding transcription factor activity
N7E70_011985	COG0640	Transcriptional regulator
N7E70_012010	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7E70_012015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N7E70_012030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_012040	COG0477	Major facilitator Superfamily
N7E70_012070	COG0436	Aminotransferase
N7E70_012090	COG1278	Cold shock
N7E70_012100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7E70_012125	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7E70_012130	COG2130	NADP-dependent
N7E70_012140	COG1864	DNA RNA non-specific endonuclease
N7E70_012140	COG3591	Belongs to the peptidase S1B family
N7E70_012155	COG2814	Major facilitator Superfamily
N7E70_012160	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_012170	COG2321	neutral zinc metallopeptidase
N7E70_012175	COG4989	oxidoreductase activity
N7E70_012195	COG1116	anion transmembrane transporter activity
N7E70_012215	COG0505	Belongs to the CarA family
N7E70_012230	COG1473	amidohydrolase
N7E70_012240	COG0358	DNA primase activity
N7E70_012245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N7E70_012260	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N7E70_012275	COG0372	Belongs to the citrate synthase family
N7E70_012280	COG0372	Belongs to the citrate synthase family
N7E70_012325	COG1280	lysine exporter protein (LysE YggA)
N7E70_012370	COG0488	(ABC) transporter
N7E70_012385	COG1522	sequence-specific DNA binding
N7E70_012395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7E70_012400	COG0583	DNA-binding transcription factor activity
N7E70_012405	COG1309	transcriptional regulator
N7E70_012430	COG2862	Uncharacterized protein family, UPF0114
N7E70_012440	COG2983	Belongs to the UPF0260 family
N7E70_012450	COG2968	Membrane
N7E70_012485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_012500	COG2814	Major facilitator Superfamily
N7E70_012510	COG4608	Belongs to the ABC transporter superfamily
N7E70_012515	COG0444	Belongs to the ABC transporter superfamily
N7E70_012520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_012525	COG0601	transmembrane transport
N7E70_012530	COG0747	negative chemotaxis
N7E70_012545	COG1473	amidohydrolase
N7E70_012550	COG1473	amidohydrolase
N7E70_012555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_012560	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_012570	COG5383	Protein conserved in bacteria
N7E70_012580	COG0837	glucose binding
N7E70_012580	COG1737	Transcriptional regulator
N7E70_012585	COG0747	negative chemotaxis
N7E70_012590	COG0601	transmembrane transport
N7E70_012595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_012600	COG0444	Belongs to the ABC transporter superfamily
N7E70_012625	COG3706	GGDEF domain
N7E70_012640	COG0463	Glycosyl transferase, family 2
N7E70_012695	COG0367	asparagine synthase
N7E70_012705	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_012710	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N7E70_012745	COG1902	pentaerythritol trinitrate reductase activity
N7E70_012765	COG0673	inositol 2-dehydrogenase activity
N7E70_012775	COG0589	response to stress
N7E70_012780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_012785	COG4597	amino acid ABC transporter
N7E70_012790	COG0765	amino acid transport
N7E70_012795	COG3685	Protein conserved in bacteria
N7E70_012805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N7E70_012810	COG4208	sulfate ABC transporter
N7E70_012815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N7E70_012820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N7E70_012830	COG4953	penicillin-binding protein 1C
N7E70_012840	COG0729	surface antigen
N7E70_012850	COG4166	transmembrane transport
N7E70_012855	COG0601	transmembrane transport
N7E70_012860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_012875	COG0493	'glutamate synthase
N7E70_012900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7E70_012915	COG1309	transcriptional regulator
N7E70_012920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7E70_012950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_012955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_012980	COG0028	Belongs to the TPP enzyme family
N7E70_012985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7E70_012990	COG2267	carboxylic ester hydrolase activity
N7E70_012995	COG1131	(ABC) transporter
N7E70_013000	COG0842	Transport permease protein
N7E70_013030	COG4106	trans-aconitate 2-methyltransferase activity
N7E70_013045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_013050	COG1522	sequence-specific DNA binding
N7E70_013060	COG1720	tRNA m6t6A37 methyltransferase activity
N7E70_013085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N7E70_013125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N7E70_013145	COG0626	cystathionine gamma-synthase activity
N7E70_013150	COG2001	Belongs to the MraZ family
N7E70_013155	COG0275	rRNA processing
N7E70_013170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N7E70_013180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7E70_013185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7E70_013195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7E70_013200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7E70_013205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N7E70_013210	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7E70_013215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N7E70_013220	COG0849	cell division
N7E70_013225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7E70_013235	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7E70_013265	COG0006	proline dipeptidase activity
N7E70_013270	COG2264	protein methyltransferase activity
N7E70_013275	COG1999	signal sequence binding
N7E70_013310	COG5002	protein histidine kinase activity
N7E70_013315	COG0745	RESPONSE REGULATOR receiver
N7E70_013330	COG0210	DNA helicase
N7E70_013355	COG0277	FAD linked oxidase domain protein
N7E70_013400	COG2814	Major facilitator Superfamily
N7E70_013405	COG3706	GGDEF domain
N7E70_013430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N7E70_013445	COG0330	HflC and HflK could
N7E70_013450	COG0330	HflC and HflK could
N7E70_013460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7E70_013470	COG0560	Phosphoserine phosphatase
N7E70_013470	COG3830	Belongs to the UPF0237 family
N7E70_013475	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N7E70_013485	COG2267	carboxylic ester hydrolase activity
N7E70_013495	COG1132	(ABC) transporter
N7E70_013500	COG0028	Belongs to the TPP enzyme family
N7E70_013505	COG0440	acetolactate synthase activity
N7E70_013555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7E70_013575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N7E70_013580	COG3158	transport of potassium into the cell
N7E70_013585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_013605	COG0583	DNA-binding transcription factor activity
N7E70_013610	COG1309	transcriptional regulator
N7E70_013615	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N7E70_013645	COG0577	efflux transmembrane transporter activity
N7E70_013645	COG1136	(ABC) transporter
N7E70_013650	COG0577	efflux transmembrane transporter activity
N7E70_013650	COG1136	(ABC) transporter
N7E70_013660	COG0384	phenazine biosynthesis protein PhzF
N7E70_013680	COG0628	permease
N7E70_013700	COG1959	2 iron, 2 sulfur cluster binding
N7E70_013705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N7E70_013710	COG4208	sulfate ABC transporter
N7E70_013720	COG4150	thiosulfate binding
N7E70_013725	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N7E70_013730	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
N7E70_013735	COG1797	cobyrinic acid a,c-diamide synthase activity
N7E70_013745	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
N7E70_013805	COG3214	Protein conserved in bacteria
N7E70_013810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_013815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_013820	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_013825	COG0649	NAD binding
N7E70_013830	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
N7E70_013835	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N7E70_013840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N7E70_013840	COG3743	rRNA binding
N7E70_013850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
N7E70_013855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7E70_013865	COG0713	ATP synthesis coupled electron transport
N7E70_013880	COG1007	ATP synthesis coupled electron transport
N7E70_013895	COG0346	lactoylglutathione lyase activity
N7E70_013905	COG0442	prolyl-tRNA aminoacylation
N7E70_013915	COG1136	(ABC) transporter
N7E70_013920	COG0442	prolyl-tRNA aminoacylation
N7E70_013930	COG0321	lipoyl(octanoyl) transferase activity
N7E70_013960	COG0789	Transcriptional regulator
N7E70_013965	COG2239	Acts as a magnesium transporter
N7E70_014045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_014075	COG0583	DNA-binding transcription factor activity
N7E70_014095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_014095	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_014105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_014110	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N7E70_014110	COG3264	Mechanosensitive ion channel
N7E70_014135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7E70_014205	COG0583	DNA-binding transcription factor activity
N7E70_014230	COG0646	methionine synthase
N7E70_014230	COG1410	methionine synthase
N7E70_014250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N7E70_014255	COG3932	Exopolysaccharide synthesis, ExoD
N7E70_014275	COG5012	cobalamin binding
N7E70_014280	COG5598	trimethylamine methyltransferase
N7E70_014290	COG2186	Transcriptional regulator
N7E70_014295	COG2807	transmembrane transport
N7E70_014305	COG2081	HI0933 family
N7E70_014320	COG2304	oxidoreductase activity
N7E70_014340	COG0646	methionine synthase
N7E70_014340	COG1410	methionine synthase
N7E70_014365	COG0006	proline dipeptidase activity
N7E70_014375	COG5598	trimethylamine methyltransferase
N7E70_014410	COG1960	acyl-CoA dehydrogenase activity
N7E70_014420	COG1492	cobalamin metabolic process
N7E70_014445	COG4172	Belongs to the ABC transporter superfamily
N7E70_014450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_014455	COG0601	transmembrane transport
N7E70_014460	COG0747	negative chemotaxis
N7E70_014465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_014490	COG0243	molybdopterin cofactor binding
N7E70_014495	COG0437	4 iron, 4 sulfur cluster binding
N7E70_014500	COG3302	dmso reductase anchor subunit
N7E70_014505	COG1560	Kdo2-lipid A biosynthetic process
N7E70_014515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7E70_014525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7E70_014555	COG1522	sequence-specific DNA binding
N7E70_014585	COG1629	transport
N7E70_014595	COG3720	iron ion transport
N7E70_014605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_014610	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
N7E70_014615	COG1959	2 iron, 2 sulfur cluster binding
N7E70_014630	COG1309	transcriptional regulator
N7E70_014640	COG2733	membrane
N7E70_014690	COG2832	Protein of unknown function (DUF454)
N7E70_014695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7E70_014700	COG2205	protein histidine kinase activity
N7E70_014745	COG2205	protein histidine kinase activity
N7E70_014750	COG1525	nuclease
N7E70_014755	COG0625	glutathione transferase activity
N7E70_014760	COG1573	uracil-dna glycosylase
N7E70_014765	COG1522	sequence-specific DNA binding
N7E70_014775	COG2084	Dehydrogenase
N7E70_014795	COG1763	Mo-molybdopterin cofactor biosynthetic process
N7E70_014800	COG0746	molybdenum cofactor guanylyltransferase activity
N7E70_014825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N7E70_014845	COG1846	Transcriptional regulator
N7E70_014850	COG0596	Alpha beta hydrolase
N7E70_014870	COG2989	Protein conserved in bacteria
N7E70_014895	COG0546	phosphoglycolate phosphatase activity
N7E70_014900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
N7E70_014915	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
N7E70_014920	COG2199	diguanylate cyclase activity
N7E70_014925	COG2514	catechol 2,3-dioxygenase activity
N7E70_014935	COG0659	secondary active sulfate transmembrane transporter activity
N7E70_014940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N7E70_014965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_014985	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N7E70_014985	COG3608	succinylglutamate desuccinylase aspartoacylase
N7E70_014990	COG0746	molybdenum cofactor guanylyltransferase activity
N7E70_015025	COG0596	Alpha beta hydrolase
N7E70_015025	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_015065	COG2855	membrane
N7E70_015090	COG0850	regulation of cytokinetic process
N7E70_015095	COG2894	cell division
N7E70_015100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
N7E70_015135	COG1607	acyl-coa hydrolase
N7E70_015140	COG0251	oxidation-reduction process
N7E70_015160	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_015210	COG1042	CoA-binding domain protein
N7E70_015210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7E70_015210	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_015220	COG0459	protein refolding
N7E70_015235	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N7E70_015240	COG2235	arginine
N7E70_015270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7E70_015315	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N7E70_015350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_015365	COG2205	protein histidine kinase activity
N7E70_015370	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_015395	COG0586	Pfam SNARE associated Golgi protein
N7E70_015410	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
N7E70_015420	COG1136	(ABC) transporter
N7E70_015435	COG5622	Protein required for attachment to host cells
N7E70_015440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7E70_015450	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
N7E70_015460	COG1546	Belongs to the CinA family
N7E70_015460	COG1058	Belongs to the CinA family
N7E70_015500	COG2267	carboxylic ester hydrolase activity
N7E70_015525	COG4191	Histidine kinase
N7E70_015530	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7E70_015545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7E70_015550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_015565	COG1278	Cold shock
N7E70_015585	COG1024	Enoyl-CoA hydratase
N7E70_015630	COG0517	IMP dehydrogenase activity
N7E70_015630	COG0516	GMP reductase activity
N7E70_015635	COG3811	Belongs to the UPF0386 family
N7E70_015640	COG5002	protein histidine kinase activity
N7E70_015640	COG3850	Histidine kinase
N7E70_015645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7E70_015655	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N7E70_015660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7E70_015685	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N7E70_015690	COG0439	Biotin carboxylase
N7E70_015695	COG0511	ligase activity, forming carbon-carbon bonds
N7E70_015700	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N7E70_015715	COG0436	Aminotransferase
N7E70_015740	COG2066	Belongs to the glutaminase family
N7E70_015905	COG0250	Participates in transcription elongation, termination and antitermination
N7E70_016070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N7E70_016085	COG0525	valine-tRNA ligase activity
N7E70_016100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
N7E70_016115	COG2233	PERMEase
N7E70_016130	COG0316	Belongs to the HesB IscA family
N7E70_016135	COG0232	Belongs to the dGTPase family. Type 2 subfamily
N7E70_016140	COG0018	arginyl-trna synthetase
N7E70_016155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N7E70_016160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_016165	COG3842	ATPase activity
N7E70_016170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7E70_016175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7E70_016180	COG0805	protein transport
N7E70_016185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N7E70_016190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N7E70_016195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N7E70_016210	COG1862	Preprotein translocase
N7E70_016220	COG3737	Protein of unknown function (DUF498/DUF598)
N7E70_016240	COG0519	Catalyzes the synthesis of GMP from XMP
N7E70_016245	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N7E70_016290	COG0544	peptidyl-prolyl cis-trans isomerase activity
N7E70_016295	COG2003	Belongs to the UPF0758 family
N7E70_016300	COG0024	Methionine aminopeptidase
N7E70_016310	COG2824	Alkylphosphonate utilization operon protein PhnA
N7E70_016320	COG1609	Transcriptional regulator
N7E70_016330	COG1175	transmembrane transport
N7E70_016335	COG0395	ABC-type sugar transport system, permease component
N7E70_016350	COG3842	ATPase activity
N7E70_016370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N7E70_016375	COG1116	anion transmembrane transporter activity
N7E70_016380	COG4149	molybdate abc transporter
N7E70_016430	COG3243	poly(R)-hydroxyalkanoic acid synthase
N7E70_016440	COG0436	Aminotransferase
N7E70_016450	COG1494	fructose-1,6-bisphosphatase
N7E70_016455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7E70_016460	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7E70_016465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N7E70_016470	COG0302	gtp cyclohydrolase
N7E70_016480	COG0583	DNA-binding transcription factor activity
N7E70_016490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N7E70_016500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7E70_016515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_016520	COG2301	Belongs to the HpcH HpaI aldolase family
N7E70_016535	COG0187	DNA topoisomerase II activity
N7E70_016550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7E70_016550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7E70_016555	COG0509	glycine decarboxylation via glycine cleavage system
N7E70_016560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_016570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7E70_016585	COG1671	Belongs to the UPF0178 family
N7E70_016595	COG2153	protein acetylation
N7E70_016600	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N7E70_016610	COG4941	Belongs to the sigma-70 factor family
N7E70_016615	COG3795	YCII-related domain
N7E70_016635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7E70_016650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7E70_016650	COG0475	glutathione-regulated potassium exporter activity
N7E70_016665	COG3768	UPF0283 membrane protein
N7E70_016670	COG3106	COG3106 Predicted ATPase
N7E70_016715	COG0513	Belongs to the DEAD box helicase family
N7E70_016725	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_016735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N7E70_016740	COG2897	thiosulfate sulfurtransferase activity
N7E70_016755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N7E70_016770	COG0686	Belongs to the AlaDH PNT family
N7E70_016775	COG1522	sequence-specific DNA binding
N7E70_016780	COG0737	Belongs to the 5'-nucleotidase family
N7E70_016790	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N7E70_016800	COG4957	zinc ion binding
N7E70_016805	COG1530	ribonuclease E activity
N7E70_016810	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7E70_016815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N7E70_016840	COG2885	chlorophyll binding
N7E70_016850	COG0513	Belongs to the DEAD box helicase family
N7E70_016855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7E70_016865	COG3706	GGDEF domain
N7E70_016885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N7E70_016895	COG1414	Transcriptional regulator
N7E70_016900	COG3960	tartronate-semialdehyde synthase activity
N7E70_016905	COG3622	Belongs to the hyi family
N7E70_016910	COG2084	Dehydrogenase
N7E70_016930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7E70_016945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N7E70_016970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7E70_016980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
N7E70_016985	COG0081	regulation of translation
N7E70_016990	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N7E70_016995	COG0222	ribosome binding
N7E70_017000	COG0085	RNA polymerase activity
N7E70_017005	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N7E70_017015	COG0531	amino acid
N7E70_017025	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N7E70_017030	COG0049	tRNA binding
N7E70_017035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N7E70_017040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N7E70_017045	COG0051	transcription antitermination factor activity, RNA binding
N7E70_017050	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N7E70_017055	COG0088	Forms part of the polypeptide exit tunnel
N7E70_017060	COG0089	rRNA binding
N7E70_017065	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N7E70_017070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N7E70_017075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N7E70_017080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N7E70_017085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N7E70_017090	COG0255	Belongs to the universal ribosomal protein uL29 family
N7E70_017095	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N7E70_017100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N7E70_017105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N7E70_017110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N7E70_017115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N7E70_017120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N7E70_017125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N7E70_017130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N7E70_017135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N7E70_017140	COG1841	ribosomal large subunit assembly
N7E70_017145	COG0200	Binds to the 23S rRNA
N7E70_017155	COG0563	adenylate kinase activity
N7E70_017160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N7E70_017165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N7E70_017170	COG0202	RNA polymerase activity
N7E70_017175	COG0203	ribosomal protein L17
N7E70_017185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N7E70_017190	COG0640	Transcriptional regulator
N7E70_017215	COG2826	transposase and inactivated derivatives, IS30 family
N7E70_017220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N7E70_017220	COG0321	lipoyl(octanoyl) transferase activity
N7E70_017225	COG0084	hydrolase, TatD family'
N7E70_017230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7E70_017240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N7E70_017245	COG1686	Belongs to the peptidase S11 family
N7E70_017285	COG2948	multi-organism process
N7E70_017300	COG3846	protein secretion by the type IV secretion system
N7E70_017315	COG3451	type IV secretory pathway VirB4
N7E70_017330	COG4962	Type ii secretion system protein e
N7E70_017350	COG0356	it plays a direct role in the translocation of protons across the membrane
N7E70_017370	COG0741	lytic transglycosylase activity
N7E70_017490	COG0708	Exodeoxyribonuclease III
N7E70_017505	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N7E70_017520	COG0583	DNA-binding transcription factor activity
N7E70_017525	COG0601	transmembrane transport
N7E70_017530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_017535	COG0444	Belongs to the ABC transporter superfamily
N7E70_017540	COG4608	Belongs to the ABC transporter superfamily
N7E70_017545	COG4166	transmembrane transport
N7E70_017685	COG2885	chlorophyll binding
N7E70_017705	COG0739	heme binding
N7E70_017715	COG0861	Integral membrane protein TerC family
N7E70_017720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7E70_017725	COG2814	Major facilitator Superfamily
N7E70_017760	COG1024	Enoyl-CoA hydratase
N7E70_017770	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017780	COG1960	acyl-CoA dehydrogenase activity
N7E70_017790	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017795	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017810	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017830	COG0183	Belongs to the thiolase family
N7E70_017835	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017845	COG1960	acyl-CoA dehydrogenase activity
N7E70_017860	COG1024	Enoyl-CoA hydratase
N7E70_017860	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_017865	COG0604	alcohol dehydrogenase
N7E70_017870	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017875	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_017885	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017925	COG0657	acetylesterase activity
N7E70_017935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_017940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_017960	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_017965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N7E70_017970	COG0183	Belongs to the thiolase family
N7E70_017975	COG1960	acyl-CoA dehydrogenase activity
N7E70_017980	COG1960	acyl-CoA dehydrogenase activity
N7E70_017985	COG1024	Enoyl-CoA hydratase
N7E70_017990	COG0667	Aldo Keto reductase
N7E70_017995	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N7E70_018030	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_018035	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_018040	COG3845	ABC transporter
N7E70_018050	COG1183	phosphatidylcholine synthase activity
N7E70_018055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_018060	COG0679	Auxin Efflux Carrier
N7E70_018075	COG4166	transmembrane transport
N7E70_018090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N7E70_018095	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N7E70_018100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N7E70_018110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N7E70_018115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N7E70_018120	COG0785	Cytochrome C biogenesis protein
N7E70_018320	COG4974	Belongs to the 'phage' integrase family
N7E70_018345	COG0861	Integral membrane protein TerC family
N7E70_018370	COG2308	Evidence 4 Homologs of previously reported genes of
N7E70_018385	COG0488	(ABC) transporter
N7E70_018400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7E70_018405	COG0343	queuine tRNA-ribosyltransferase activity
N7E70_018410	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N7E70_018430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N7E70_018440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7E70_018445	COG2095	MarC family integral membrane protein
N7E70_018460	COG0629	single-stranded DNA binding
N7E70_018470	COG2188	Transcriptional regulator
N7E70_018480	COG0395	ABC-type sugar transport system, permease component
N7E70_018500	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_018510	COG1794	racemase activity, acting on amino acids and derivatives
N7E70_018515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N7E70_018545	COG1309	transcriptional regulator
N7E70_018550	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_018555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N7E70_018555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N7E70_018560	COG0347	Belongs to the P(II) protein family
N7E70_018565	COG0174	glutamine synthetase
N7E70_018595	COG0174	glutamine synthetase
N7E70_018605	COG0697	spore germination
N7E70_018620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7E70_018625	COG3956	TIGRFAM MazG family protein
N7E70_018630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N7E70_018635	COG1923	regulation of RNA biosynthetic process
N7E70_018640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_018645	COG0569	domain protein
N7E70_018650	COG2204	response regulator
N7E70_018655	COG5000	phosphorelay sensor kinase activity
N7E70_018660	COG2204	response regulator
N7E70_018665	COG3852	Histidine kinase
N7E70_018675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N7E70_018675	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N7E70_018680	COG1058	Belongs to the CinA family
N7E70_018680	COG1546	Belongs to the CinA family
N7E70_018690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N7E70_018700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7E70_018705	COG0456	acetyltransferase
N7E70_018705	COG1214	PFAM Peptidase M22, glycoprotease
N7E70_018715	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_018720	COG0022	dehydrogenase e1 component
N7E70_018720	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_018725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7E70_018730	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N7E70_018735	COG0148	phosphopyruvate hydratase activity
N7E70_018750	COG2877	3-deoxy-8-phosphooctulonate synthase activity
N7E70_018765	COG0504	CTP synthase activity
N7E70_018780	COG0149	triose-phosphate isomerase activity
N7E70_018790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N7E70_018795	COG0134	indole-3-glycerol-phosphate synthase activity
N7E70_018800	COG0315	cyclic pyranopterin monophosphate synthase activity
N7E70_018805	COG0303	'Molybdopterin
N7E70_018810	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N7E70_018820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7E70_018825	COG0372	Belongs to the citrate synthase family
N7E70_018830	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7E70_018840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7E70_018845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7E70_018850	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7E70_018855	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7E70_018860	COG0750	zinc metalloprotease
N7E70_018870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N7E70_018875	COG0233	cytoplasmic translational termination
N7E70_018880	COG0528	UMP kinase activity
N7E70_018885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N7E70_018890	COG0052	Belongs to the universal ribosomal protein uS2 family
N7E70_018925	COG0537	adenosine 5'-monophosphoramidase activity
N7E70_018950	COG3706	GGDEF domain
N7E70_018960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N7E70_018970	COG1686	Belongs to the peptidase S11 family
N7E70_018975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
N7E70_018990	COG1760	l-serine dehydratase
N7E70_019005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
N7E70_019010	COG0154	amidase activity
N7E70_019015	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7E70_019025	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N7E70_019030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N7E70_019040	COG1960	acyl-CoA dehydrogenase activity
N7E70_019045	COG0540	Belongs to the ATCase OTCase family
N7E70_019050	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7E70_019055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N7E70_019060	COG0758	DNA mediated transformation
N7E70_019065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7E70_019070	COG0557	exoribonuclease II activity
N7E70_019090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N7E70_019100	COG0784	Response regulator, receiver
N7E70_019115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N7E70_019120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N7E70_019125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N7E70_019135	COG0492	ferredoxin-NADP+ reductase activity
N7E70_019140	COG0633	Ferredoxin
N7E70_019155	COG3218	ABC-type transport auxiliary lipoprotein component
N7E70_019155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N7E70_019165	COG1127	ABC transporter
N7E70_019175	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_019190	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_019195	COG0281	malic enzyme
N7E70_019195	COG0280	phosphate acetyltransferase
N7E70_019205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7E70_019210	COG1132	(ABC) transporter
N7E70_019215	COG0640	Transcriptional regulator
N7E70_019225	COG0740	serine-type endopeptidase activity
N7E70_019265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N7E70_019270	COG3384	dioxygenase
N7E70_019280	COG0519	Catalyzes the synthesis of GMP from XMP
N7E70_019300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N7E70_019305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7E70_019310	COG0047	phosphoribosylformylglycinamidine synthase activity
N7E70_019325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_019330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7E70_019345	COG2226	methyltransferase
N7E70_019355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N7E70_019360	COG2814	Major facilitator Superfamily
N7E70_019365	COG0037	tRNA processing
N7E70_019370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N7E70_019380	COG1733	regulation of RNA biosynthetic process
N7E70_019385	COG0702	epimerase
N7E70_019395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7E70_019410	COG0538	isocitrate dehydrogenase activity
N7E70_019425	COG0346	lactoylglutathione lyase activity
N7E70_019430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N7E70_019435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N7E70_019445	COG2313	pseudouridylate synthase activity
N7E70_019460	COG0316	Belongs to the HesB IscA family
N7E70_019475	COG2151	metal-sulfur cluster biosynthetic enzyme
N7E70_019480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7E70_019485	COG0719	Fe-S assembly protein
N7E70_019490	COG0396	ATPase activity
N7E70_019500	COG0719	Fe-S assembly protein
N7E70_019510	COG2945	thiolester hydrolase activity
N7E70_019540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7E70_019550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N7E70_019555	COG0739	heme binding
N7E70_019585	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
N7E70_019595	COG0411	ABC transporter
N7E70_019605	COG0559	Belongs to the binding-protein-dependent transport system permease family
N7E70_019625	COG1917	Cupin 2, conserved barrel domain protein
N7E70_019630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_019640	COG0583	DNA-binding transcription factor activity
N7E70_019660	COG0583	DNA-binding transcription factor activity
N7E70_019680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N7E70_019690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N7E70_019695	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_019705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7E70_019710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7E70_019725	COG4608	Belongs to the ABC transporter superfamily
N7E70_019730	COG0444	Belongs to the ABC transporter superfamily
N7E70_019735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_019740	COG0601	transmembrane transport
N7E70_019745	COG1396	sequence-specific DNA binding
N7E70_019750	COG0747	negative chemotaxis
N7E70_019770	COG0776	regulation of translation
N7E70_019780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N7E70_019785	COG0740	serine-type endopeptidase activity
N7E70_019830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N7E70_019835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N7E70_019850	COG0584	glycerophosphoryl diester phosphodiesterase
N7E70_019855	COG0010	Belongs to the arginase family
N7E70_019870	COG1612	heme a metabolic process
N7E70_019900	COG0297	glycogen (starch) synthase activity
N7E70_019935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N7E70_019950	COG0776	regulation of translation
N7E70_019955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7E70_019960	COG0416	fatty acid biosynthetic process
N7E70_019975	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7E70_019980	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
N7E70_019995	COG1174	glycine betaine transport
N7E70_020000	COG1125	glycine betaine transport
N7E70_020005	COG1174	glycine betaine transport
N7E70_020010	COG1732	Glycine betaine
N7E70_020015	COG2814	Major facilitator Superfamily
N7E70_020020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7E70_020025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N7E70_020035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7E70_020035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7E70_020040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N7E70_020045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N7E70_020055	COG2989	Protein conserved in bacteria
N7E70_020075	COG0113	porphobilinogen synthase activity
N7E70_020085	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
N7E70_020095	COG0628	permease
N7E70_020100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7E70_020110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N7E70_020125	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
N7E70_020150	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
N7E70_020200	COG2235	arginine
N7E70_020270	COG0730	response to heat
N7E70_020280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_020290	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_020295	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N7E70_020300	COG1349	DNA-binding transcription factor activity
N7E70_020315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N7E70_020320	COG0583	DNA-binding transcription factor activity
N7E70_020330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_020335	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N7E70_020340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7E70_020345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N7E70_020350	COG2188	Transcriptional regulator
N7E70_020375	COG0583	DNA-binding transcription factor activity
N7E70_020380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7E70_020405	COG1653	transport
N7E70_020430	COG3842	ATPase activity
N7E70_020435	COG2252	PERMEase
N7E70_020450	COG3842	ATPase activity
N7E70_020460	COG0395	ABC-type sugar transport system, permease component
N7E70_020475	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N7E70_020485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7E70_020490	COG1132	(ABC) transporter
N7E70_020495	COG3459	Glycosyltransferase 36 associated
N7E70_020510	COG3314	Sporulation integral membrane protein YlbJ
N7E70_020515	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N7E70_020525	COG2986	histidine ammonia-lyase
N7E70_020530	COG1228	amidohydrolase
N7E70_020555	COG0251	oxidation-reduction process
N7E70_020565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7E70_020570	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7E70_020580	COG0523	cobalamin synthesis protein
N7E70_020600	COG1234	tRNA 3'-trailer cleavage
N7E70_020610	COG1063	alcohol dehydrogenase
N7E70_020625	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_020635	COG1960	acyl-CoA dehydrogenase activity
N7E70_020645	COG1902	pentaerythritol trinitrate reductase activity
N7E70_020645	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_020650	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N7E70_020665	COG5598	trimethylamine methyltransferase
N7E70_020670	COG0583	DNA-binding transcription factor activity
N7E70_020675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N7E70_020695	COG1663	tetraacyldisaccharide 4'-kinase activity
N7E70_020700	COG1519	Transferase
N7E70_020715	COG0483	inositol monophosphate 1-phosphatase activity
N7E70_020720	COG0312	modulator of DNA gyrase
N7E70_020735	COG0612	Peptidase, M16
N7E70_020740	COG0612	Peptidase, M16
N7E70_020745	COG0742	ribosomal rna small subunit methyltransferase
N7E70_020750	COG1187	pseudouridine synthase activity
N7E70_020755	COG0590	tRNA wobble adenosine to inosine editing
N7E70_020765	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N7E70_020780	COG0196	riboflavin kinase activity
N7E70_020795	COG2814	Major facilitator Superfamily
N7E70_020805	COG1846	Transcriptional regulator
N7E70_020810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N7E70_020810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7E70_020820	COG0459	protein refolding
N7E70_020850	COG3237	CsbD-like
N7E70_020865	COG0114	fumarate hydratase activity
N7E70_020870	COG2259	Doxx family
N7E70_020880	COG0248	Ppx GppA phosphatase
N7E70_020885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N7E70_020895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7E70_020905	COG1126	abc transporter atp-binding protein
N7E70_020910	COG0765	amino acid transport
N7E70_020915	COG4597	amino acid ABC transporter
N7E70_020920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_020930	COG0626	cystathionine gamma-synthase activity
N7E70_020940	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N7E70_020950	COG3852	Histidine kinase
N7E70_020995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N7E70_021005	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N7E70_021175	COG3657	addiction module killer protein
N7E70_021180	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7E70_021205	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_021215	COG0583	DNA-binding transcription factor activity
N7E70_021220	COG2207	Transcriptional regulator
N7E70_021230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_021240	COG0747	negative chemotaxis
N7E70_021245	COG0601	transmembrane transport
N7E70_021250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_021255	COG0444	Belongs to the ABC transporter superfamily
N7E70_021265	COG2207	Transcriptional regulator
N7E70_021285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N7E70_021295	COG5425	PFAM Usg family protein
N7E70_021305	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_021310	COG0071	Belongs to the small heat shock protein (HSP20) family
N7E70_021330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7E70_021335	COG0454	-acetyltransferase
N7E70_021340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7E70_021345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_021350	COG0745	RESPONSE REGULATOR receiver
N7E70_021355	COG5002	protein histidine kinase activity
N7E70_021365	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N7E70_021415	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_021420	COG1129	ABC transporter
N7E70_021425	COG0702	epimerase
N7E70_021435	COG2186	Transcriptional regulator
N7E70_021450	COG2186	Transcriptional regulator
N7E70_021460	COG1136	(ABC) transporter
N7E70_021535	COG0210	DNA helicase
N7E70_021540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7E70_021555	COG0583	DNA-binding transcription factor activity
N7E70_021565	COG0747	negative chemotaxis
N7E70_021575	COG3265	gluconokinase activity
N7E70_021580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_021590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7E70_021595	COG2084	Dehydrogenase
N7E70_021640	COG0464	growth
N7E70_021685	COG0444	Belongs to the ABC transporter superfamily
N7E70_021690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_021705	COG0747	negative chemotaxis
N7E70_021710	COG2186	Transcriptional regulator
N7E70_021720	COG1473	amidohydrolase
N7E70_021730	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N7E70_021740	COG3474	cytochrome
N7E70_021855	COG0210	DNA helicase
N7E70_021895	COG0640	Transcriptional regulator
N7E70_021900	COG0798	PFAM Bile acid sodium symporter
N7E70_021910	COG0431	NADPH-dependent FMN reductase
N7E70_021935	COG0753	catalase activity
N7E70_021980	COG1278	Cold shock
N7E70_021990	COG0784	Response regulator, receiver
N7E70_021990	COG4191	Histidine kinase
N7E70_022000	COG3685	Protein conserved in bacteria
N7E70_022005	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_022080	COG2827	Endonuclease containing a URI domain
N7E70_022120	COG2205	protein histidine kinase activity
N7E70_022120	COG0784	Response regulator, receiver
N7E70_022125	COG2197	response regulator
N7E70_022130	COG1280	lysine exporter protein (LysE YggA)
N7E70_022145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_022155	COG0747	negative chemotaxis
N7E70_022185	COG0628	permease
N7E70_022190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N7E70_022195	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N7E70_022200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N7E70_022230	COG0583	DNA-binding transcription factor activity
N7E70_022240	COG1024	Enoyl-CoA hydratase
N7E70_022245	COG1960	acyl-CoA dehydrogenase activity
N7E70_022250	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_022255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_022280	COG0583	DNA-binding transcription factor activity
N7E70_022285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_022290	COG0765	amino acid transport
N7E70_022300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N7E70_022315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7E70_022345	COG0243	molybdopterin cofactor binding
N7E70_022350	COG0488	(ABC) transporter
N7E70_022355	COG2211	Major facilitator Superfamily
N7E70_022375	COG0105	UTP biosynthetic process
N7E70_022385	COG0314	molybdopterin synthase activity
N7E70_022400	COG0322	excinuclease ABC activity
N7E70_022445	COG0625	glutathione transferase activity
N7E70_022460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N7E70_022485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N7E70_022510	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N7E70_022515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N7E70_022540	COG0194	GDP metabolic process
N7E70_022545	COG1561	YicC-like family, N-terminal region
N7E70_022550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7E70_022555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7E70_022560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7E70_022570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7E70_022575	COG1368	sulfuric ester hydrolase activity
N7E70_022580	COG0360	Binds together with S18 to 16S ribosomal RNA
N7E70_022590	COG0359	binds to the 23S rRNA
N7E70_022595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
N7E70_022600	COG1742	UPF0060 membrane protein
N7E70_022605	COG3468	outer membrane autotransporter barrel domain protein
N7E70_022610	COG0305	Participates in initiation and elongation during chromosome replication
N7E70_022625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7E70_022635	COG4221	oxidoreductase activity
N7E70_022640	COG3273	potassium ion transport
N7E70_022640	COG0471	metal ion transport
N7E70_022665	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_022665	COG0204	Acyl-transferase
N7E70_022675	COG0688	phosphatidylethanolamine metabolic process
N7E70_022680	COG5265	(ABC) transporter
N7E70_022690	COG1652	LysM domain
N7E70_022705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7E70_022735	COG2852	Protein conserved in bacteria
N7E70_022740	COG0215	cysteine-tRNA ligase activity
N7E70_022780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7E70_022790	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
N7E70_022815	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_022825	COG0640	Transcriptional regulator
N7E70_022860	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
N7E70_022890	COG1381	Involved in DNA repair and RecF pathway recombination
N7E70_022895	COG0477	Major facilitator Superfamily
N7E70_022915	COG2814	Major facilitator Superfamily
N7E70_022935	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_022965	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_022980	COG1280	lysine exporter protein (LysE YggA)
N7E70_023025	COG0300	oxidoreductase activity
N7E70_023040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N7E70_023045	COG0571	ribonuclease III activity
N7E70_023050	COG0681	Belongs to the peptidase S26 family
N7E70_023055	COG0736	holo-[acyl-carrier-protein] synthase activity
N7E70_023060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N7E70_023070	COG1758	RNA polymerase activity
N7E70_023095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N7E70_023100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_023105	COG0741	lytic transglycosylase activity
N7E70_023130	COG4974	Belongs to the 'phage' integrase family
N7E70_023145	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
N7E70_023150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_023160	COG1960	acyl-CoA dehydrogenase activity
N7E70_023180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7E70_023185	COG4770	biotin carboxylase activity
N7E70_023200	COG0450	alkyl hydroperoxide reductase
N7E70_023220	COG0625	glutathione transferase activity
N7E70_023230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N7E70_023260	COG1573	uracil-dna glycosylase
N7E70_023275	COG0438	transferase activity, transferring glycosyl groups
N7E70_023290	COG0308	aminopeptidase N
N7E70_023295	COG2205	protein histidine kinase activity
N7E70_023295	COG2202	Pas domain
N7E70_023300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_023315	COG2205	protein histidine kinase activity
N7E70_023320	COG0745	RESPONSE REGULATOR receiver
N7E70_023325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7E70_023330	COG3088	subunit of a heme lyase
N7E70_023335	COG1138	Cytochrome C-type biogenesis protein
N7E70_023340	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
N7E70_023345	COG4235	cytochrome complex assembly
N7E70_023375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
N7E70_023410	COG2205	protein histidine kinase activity
N7E70_023420	COG2166	iron-sulfur cluster assembly
N7E70_023425	COG4957	zinc ion binding
N7E70_023430	COG1320	monovalent cation:proton antiporter activity
N7E70_023435	COG2212	antiporter activity
N7E70_023440	COG1863	multisubunit Na H antiporter MnhE subunit
N7E70_023445	COG0651	ATP synthesis coupled electron transport
N7E70_023450	COG1006	Multisubunit Na H antiporter MnhC subunit
N7E70_023455	COG2111	Na H antiporter
N7E70_023460	COG2111	Na H antiporter
N7E70_023460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7E70_023475	COG2010	Cytochrome c
N7E70_023480	COG3909	cytochrome
N7E70_023485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7E70_023490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7E70_023500	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_023505	COG0433	COG0433 Predicted ATPase
N7E70_023510	COG2336	PFAM SpoVT AbrB
N7E70_023515	COG3654	unkown
N7E70_023520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_023530	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_023535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7E70_023540	COG1309	transcriptional regulator
N7E70_023545	COG3119	arylsulfatase activity
N7E70_023555	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
N7E70_023560	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_023570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7E70_023590	COG4172	Belongs to the ABC transporter superfamily
N7E70_023595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_023600	COG0601	transmembrane transport
N7E70_023610	COG0366	Alpha amylase catalytic
N7E70_023615	COG1523	belongs to the glycosyl hydrolase 13 family
N7E70_023620	COG0033	Phosphoglucomutase
N7E70_023625	COG0297	glycogen (starch) synthase activity
N7E70_023630	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N7E70_023635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
N7E70_023640	COG0058	SHG alpha-glucan phosphorylase activity
N7E70_023660	COG1940	carbohydrate kinase activity
N7E70_023680	COG1218	3'(2'),5'-bisphosphate nucleotidase
N7E70_023690	COG0175	sulfate reduction
N7E70_023720	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_023735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7E70_023735	COG0574	Belongs to the PEP-utilizing enzyme family
N7E70_023760	COG0829	nickel cation binding
N7E70_023765	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N7E70_023770	COG0804	urea catabolic process
N7E70_023775	COG0831	urea catabolic process
N7E70_023775	COG0832	Belongs to the urease beta subunit family
N7E70_023780	COG0830	nickel cation binding
N7E70_023825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_023835	COG0010	Belongs to the arginase family
N7E70_023885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7E70_023890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7E70_023900	COG1196	nuclear chromosome segregation
N7E70_023905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7E70_023915	COG1194	a g-specific adenine glycosylase
N7E70_023920	COG1011	Hydrolase
N7E70_023925	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N7E70_023930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_023945	COG0612	Peptidase, M16
N7E70_023950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7E70_023960	COG1678	Uncharacterized ACR, COG1678
N7E70_023970	COG0678	peroxiredoxin activity
N7E70_023975	COG0328	RNA-DNA hybrid ribonuclease activity
N7E70_023980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7E70_023985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N7E70_023990	COG3346	SURF1 family
N7E70_024010	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
N7E70_024020	COG0109	protoheme IX farnesyltransferase activity
N7E70_024025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7E70_024030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7E70_024030	COG1565	acr, cog1565
N7E70_024050	COG0312	modulator of DNA gyrase
N7E70_024060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7E70_024070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N7E70_024075	COG1741	Belongs to the pirin family
N7E70_024085	COG1722	exodeoxyribonuclease VII activity
N7E70_024090	COG0123	including yeast histone deacetylase and acetoin utilization protein
N7E70_024095	COG1309	transcriptional regulator
N7E70_024115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7E70_024115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7E70_024120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N7E70_024130	COG0406	alpha-ribazole phosphatase activity
N7E70_024135	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N7E70_024150	COG0259	pyridoxamine-phosphate oxidase activity
N7E70_024160	COG1960	acyl-CoA dehydrogenase activity
N7E70_024170	COG0151	Belongs to the GarS family
N7E70_024175	COG4115	mRNA cleavage
N7E70_024200	COG0009	L-threonylcarbamoyladenylate synthase
N7E70_024210	COG0751	glycine-tRNA ligase activity
N7E70_024220	COG0752	glycyl-tRNA synthetase alpha subunit
N7E70_024230	COG0142	geranyltranstransferase activity
N7E70_024255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N7E70_024260	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7E70_024275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7E70_024285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N7E70_024290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N7E70_024295	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7E70_024300	COG0356	it plays a direct role in the translocation of protons across the membrane
N7E70_024315	COG1160	GTP binding
N7E70_024330	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
N7E70_024335	COG3788	relative of glutathione S-transferase, MAPEG superfamily
N7E70_024345	COG0583	DNA-binding transcription factor activity
N7E70_024350	COG1393	Belongs to the ArsC family
N7E70_024355	COG0251	oxidation-reduction process
N7E70_024365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_024385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7E70_024395	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_024410	COG0494	nUDIX hydrolase
N7E70_024415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_024430	COG0657	acetylesterase activity
N7E70_024440	COG0583	DNA-binding transcription factor activity
N7E70_024445	COG0242	peptide deformylase activity
N7E70_024465	COG4172	Belongs to the ABC transporter superfamily
N7E70_024470	COG0444	Belongs to the ABC transporter superfamily
N7E70_024475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_024480	COG0601	transmembrane transport
N7E70_024530	COG0840	transmembrane signaling receptor activity
N7E70_024535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7E70_024545	COG3386	PFAM SMP-30 Gluconolaconase
N7E70_024550	COG0800	Aldolase
N7E70_024555	COG3734	2-keto-3-deoxy-galactonokinase
N7E70_024560	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_024565	COG2017	converts alpha-aldose to the beta-anomer
N7E70_024575	COG1129	ABC transporter
N7E70_024585	COG2186	Transcriptional regulator
N7E70_024590	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_024610	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_024615	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_024620	COG3845	ABC transporter
N7E70_024625	COG0583	DNA-binding transcription factor activity
N7E70_024635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N7E70_024640	COG0163	prenyltransferase activity
N7E70_024660	COG0523	cobalamin synthesis protein
N7E70_024665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N7E70_024680	COG2233	PERMEase
N7E70_024685	COG0583	DNA-binding transcription factor activity
N7E70_024700	COG0431	NADPH-dependent FMN reductase
N7E70_024750	COG1959	2 iron, 2 sulfur cluster binding
N7E70_024755	COG2346	COG2346, Truncated hemoglobins
N7E70_024770	COG3278	Belongs to the heme-copper respiratory oxidase family
N7E70_024785	COG2010	Cytochrome c
N7E70_024825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7E70_024845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
N7E70_024855	COG0826	peptidase U32
N7E70_024865	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7E70_024875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N7E70_024880	COG2186	Transcriptional regulator
N7E70_024905	COG2151	metal-sulfur cluster biosynthetic enzyme
N7E70_024970	COG3794	PFAM blue (type 1) copper domain protein
N7E70_024990	COG2814	Major facilitator Superfamily
N7E70_025010	COG3005	denitrification pathway
N7E70_025035	COG4459	periplasmic nitrate reductase
N7E70_025040	COG1959	2 iron, 2 sulfur cluster binding
N7E70_025065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7E70_025080	COG0714	Associated with various cellular activities
N7E70_025085	COG3256	nitric oxide reductase
N7E70_025100	COG1845	cytochrome c oxidase, subunit III
N7E70_025125	COG4521	taurine ABC transporter
N7E70_025155	COG5489	Protein of unknown function (DUF736)
N7E70_025165	COG3916	Acyl-homoserine-lactone synthase
N7E70_025170	COG2197	response regulator
N7E70_025180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N7E70_025185	COG1476	TRANSCRIPTIONal
N7E70_025240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_025245	COG0765	amino acid transport
N7E70_025250	COG0765	amino acid transport
N7E70_025255	COG1126	abc transporter atp-binding protein
N7E70_025260	COG3608	succinylglutamate desuccinylase aspartoacylase
N7E70_025300	COG0741	lytic transglycosylase activity
N7E70_025305	COG2433	Pfam Transposase IS66
N7E70_025310	COG3436	PFAM IS66 Orf2 family protein
N7E70_025335	COG1522	sequence-specific DNA binding
N7E70_025345	COG4962	Type ii secretion system protein e
N7E70_025350	COG3838	Conjugal transfer protein Trbc
N7E70_025360	COG3451	type IV secretory pathway VirB4
N7E70_025375	COG3846	protein secretion by the type IV secretion system
N7E70_025390	COG2948	multi-organism process
N7E70_025405	COG3550	peptidyl-serine autophosphorylation
N7E70_025410	COG1396	sequence-specific DNA binding
N7E70_025445	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
N7E70_025450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N7E70_025450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7E70_025455	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
N7E70_025460	COG0583	DNA-binding transcription factor activity
N7E70_025465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N7E70_025470	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N7E70_025475	COG0124	histidyl-tRNA synthetase
N7E70_025490	COG2818	Glycosylase
N7E70_025495	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_025500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N7E70_025505	COG1388	LysM domain
N7E70_025505	COG1376	ErfK ybiS ycfS ynhG family protein
N7E70_025515	COG0247	lactate metabolic process
N7E70_025530	COG2852	Protein conserved in bacteria
N7E70_025540	COG0277	FAD linked oxidase domain protein
N7E70_025550	COG2186	Transcriptional regulator
N7E70_025555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7E70_025620	COG0583	DNA-binding transcription factor activity
N7E70_025625	COG1570	exodeoxyribonuclease VII activity
N7E70_025640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7E70_025645	COG1178	ABC-type Fe3 transport system permease component
N7E70_025650	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_025655	COG2205	protein histidine kinase activity
N7E70_025660	COG5490	Phasin protein
N7E70_025685	COG1177	transmembrane transport
N7E70_025690	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_025695	COG3842	ATPase activity
N7E70_025710	COG0431	NADPH-dependent FMN reductase
N7E70_025715	COG2814	Major facilitator Superfamily
N7E70_025725	COG3300	MHYT domain
N7E70_025725	COG5001	Diguanylate cyclase
N7E70_025735	COG2224	Isocitrate lyase
N7E70_025755	COG0174	glutamine synthetase
N7E70_025760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_025770	COG0745	RESPONSE REGULATOR receiver
N7E70_025785	COG3794	PFAM blue (type 1) copper domain protein
N7E70_025810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N7E70_025815	COG0363	glucosamine-6-phosphate deaminase activity
N7E70_025820	COG0129	dihydroxy-acid dehydratase activity
N7E70_025830	COG0488	(ABC) transporter
N7E70_025845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N7E70_025865	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N7E70_025900	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N7E70_025905	COG4149	molybdate abc transporter
N7E70_025910	COG0725	ABC transporter, periplasmic molybdate-binding protein
N7E70_025915	COG0730	response to heat
N7E70_025920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7E70_025925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7E70_025935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7E70_025955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7E70_025965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N7E70_025970	COG5328	Belongs to the UPF0262 family
N7E70_025980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N7E70_025985	COG0424	maF-like protein
N7E70_025990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N7E70_026000	COG3300	MHYT domain
N7E70_026000	COG5001	Diguanylate cyclase
N7E70_026010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_026015	COG2186	Transcriptional regulator
N7E70_026045	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N7E70_026050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_026080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_026090	COG0251	oxidation-reduction process
N7E70_026100	COG0765	amino acid transport
N7E70_026105	COG0765	amino acid transport
N7E70_026125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7E70_026130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_026135	COG1120	ATPase activity
N7E70_026140	COG3585	molybdate ion transport
N7E70_026155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_026160	COG4215	(ABC) transporter
N7E70_026165	COG0765	amino acid transport
N7E70_026170	COG3457	Alanine racemase
N7E70_026175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_026185	COG0156	8-amino-7-oxononanoate synthase activity
N7E70_026190	COG0436	Aminotransferase
N7E70_026195	COG1970	mechanosensitive ion channel activity
N7E70_026200	COG0784	Response regulator, receiver
N7E70_026200	COG2198	Histidine kinase
N7E70_026200	COG2205	protein histidine kinase activity
N7E70_026220	COG0167	dihydroorotate dehydrogenase activity
N7E70_026230	COG0123	including yeast histone deacetylase and acetoin utilization protein
N7E70_026240	COG5001	Diguanylate cyclase
N7E70_026250	COG0463	Glycosyl transferase, family 2
N7E70_026265	COG0717	Belongs to the dCTP deaminase family
N7E70_026275	COG2967	ApaG domain
N7E70_026285	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N7E70_026290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7E70_026300	COG0598	Magnesium transport protein CorA
N7E70_026305	COG0704	Plays a role in the regulation of phosphate uptake
N7E70_026315	COG0640	Transcriptional regulator
N7E70_026320	COG5002	protein histidine kinase activity
N7E70_026325	COG2326	polyphosphate kinase activity
N7E70_026330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_026340	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
N7E70_026370	COG1024	Enoyl-CoA hydratase
N7E70_026370	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_026375	COG0183	Belongs to the thiolase family
N7E70_026380	COG1960	acyl-CoA dehydrogenase activity
N7E70_026385	COG1960	acyl-CoA dehydrogenase activity
N7E70_026395	COG0730	response to heat
N7E70_026405	COG0789	Transcriptional regulator
N7E70_026415	COG1201	RNA secondary structure unwinding
N7E70_026435	COG1793	dna ligase
N7E70_026500	COG3422	double-strand break repair
N7E70_026515	COG0444	Belongs to the ABC transporter superfamily
N7E70_026520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_026530	COG0747	negative chemotaxis
N7E70_026535	COG4608	Belongs to the ABC transporter superfamily
N7E70_026540	COG0444	Belongs to the ABC transporter superfamily
N7E70_026545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_026550	COG0601	transmembrane transport
N7E70_026555	COG0747	negative chemotaxis
N7E70_026570	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_026575	COG0546	phosphoglycolate phosphatase activity
N7E70_026580	COG0024	Methionine aminopeptidase
N7E70_026600	COG2226	methyltransferase
N7E70_026605	COG0129	dihydroxy-acid dehydratase activity
N7E70_026675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_026680	COG0166	Belongs to the GPI family
N7E70_026695	COG0489	protein tyrosine kinase activity
N7E70_026720	COG0583	DNA-binding transcription factor activity
N7E70_026735	COG3383	formate dehydrogenase (NAD+) activity
N7E70_026740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N7E70_026750	COG2267	carboxylic ester hydrolase activity
N7E70_026785	COG5002	protein histidine kinase activity
N7E70_026790	COG1349	DNA-binding transcription factor activity
N7E70_026800	COG0517	IMP dehydrogenase activity
N7E70_026800	COG4175	Glycine betaine
N7E70_026805	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_026820	COG2340	Cysteine-rich secretory protein family
N7E70_026825	COG0697	spore germination
N7E70_026835	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_026840	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7E70_026845	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7E70_026850	COG3845	ABC transporter
N7E70_026860	COG1132	(ABC) transporter
N7E70_026865	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_026870	COG0288	reversible hydration of carbon dioxide
N7E70_026910	COG5002	protein histidine kinase activity
N7E70_026915	COG0230	Belongs to the bacterial ribosomal protein bL34 family
N7E70_026920	COG0594	ribonuclease P activity
N7E70_026925	COG0706	membrane insertase activity
N7E70_026935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N7E70_026945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7E70_026950	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
N7E70_026965	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N7E70_026980	COG3186	Phenylalanine-4-hydroxylase
N7E70_026990	COG0477	Major facilitator Superfamily
N7E70_026995	COG3706	GGDEF domain
N7E70_027015	COG2171	N-acyltransferase activity
N7E70_027025	COG3152	Membrane
N7E70_027045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_027065	COG0101	tRNA pseudouridine synthase activity
N7E70_027075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N7E70_027080	COG0242	peptide deformylase activity
N7E70_027120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_027130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N7E70_027135	COG3409	Peptidoglycan-binding domain 1 protein
N7E70_027135	COG3773	Cell wall hydrolase
N7E70_027145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N7E70_027150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N7E70_027170	COG2816	NAD+ diphosphatase activity
N7E70_027175	COG2226	methyltransferase
N7E70_027180	COG0077	Prephenate dehydratase
N7E70_027180	COG1605	Chorismate mutase
N7E70_027185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
N7E70_027190	COG3474	cytochrome
N7E70_027195	COG4166	transmembrane transport
N7E70_027200	COG4166	transmembrane transport
N7E70_027205	COG4174	ABC transporter (Permease)
N7E70_027210	COG4239	(ABC) transporter, permease
N7E70_027215	COG4172	Belongs to the ABC transporter superfamily
N7E70_027225	COG0791	NLP P60 protein
N7E70_027235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N7E70_027270	COG4964	Belongs to the GSP D family
N7E70_027305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N7E70_027310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N7E70_027315	COG1024	Enoyl-CoA hydratase
N7E70_027320	COG0268	Binds directly to 16S ribosomal RNA
N7E70_027325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N7E70_027330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_027345	COG0028	Belongs to the TPP enzyme family
N7E70_027350	COG2855	membrane
N7E70_027370	COG0829	nickel cation binding
N7E70_027375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
N7E70_027380	COG0804	urea catabolic process
N7E70_027385	COG0832	Belongs to the urease beta subunit family
N7E70_027385	COG0831	urea catabolic process
N7E70_027390	COG0830	nickel cation binding
N7E70_027400	COG1126	abc transporter atp-binding protein
N7E70_027435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_027470	COG0559	Belongs to the binding-protein-dependent transport system permease family
N7E70_027480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_027485	COG0720	synthase
N7E70_027495	COG5001	Diguanylate cyclase
N7E70_027510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_027525	COG1921	L-seryl-tRNASec selenium transferase activity
N7E70_027540	COG3964	amidohydrolase
N7E70_027550	COG0601	transmembrane transport
N7E70_027555	COG0747	negative chemotaxis
N7E70_027570	COG1177	transmembrane transport
N7E70_027585	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_027590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_027600	COG0583	DNA-binding transcription factor activity
N7E70_027605	COG1129	ABC transporter
N7E70_027615	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_027630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7E70_027635	COG1940	carbohydrate kinase activity
N7E70_027650	COG0517	IMP dehydrogenase activity
N7E70_027650	COG4175	Glycine betaine
N7E70_027655	COG4176	ABC-type proline glycine betaine transport system permease component
N7E70_027665	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_027685	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_027690	COG0583	DNA-binding transcription factor activity
N7E70_027700	COG3806	Anti-sigma factor
N7E70_027705	COG1595	DNA-templated transcription, initiation
N7E70_027720	COG0300	oxidoreductase activity
N7E70_027750	COG2188	Transcriptional regulator
N7E70_027760	COG1940	carbohydrate kinase activity
N7E70_027760	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
N7E70_027770	COG1175	transmembrane transport
N7E70_027775	COG0395	ABC-type sugar transport system, permease component
N7E70_027785	COG0235	Class ii aldolase
N7E70_027790	COG3254	rhamnose metabolic process
N7E70_027795	COG4952	isomerase
N7E70_027805	COG1070	Carbohydrate kinase
N7E70_027820	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_027825	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7E70_027830	COG1129	ABC transporter
N7E70_027880	COG3002	Belongs to the UPF0753 family
N7E70_027910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_027920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
N7E70_027920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N7E70_027930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7E70_027935	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_027945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N7E70_027950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_027955	COG0583	DNA-binding transcription factor activity
N7E70_027980	COG2801	Transposase and inactivated derivatives
N7E70_027980	COG3415	Transposase
N7E70_028020	COG0471	metal ion transport
N7E70_028020	COG0490	domain, Protein
N7E70_028035	COG2610	gluconate transmembrane transporter activity
N7E70_028080	COG0651	ATP synthesis coupled electron transport
N7E70_028085	COG0651	ATP synthesis coupled electron transport
N7E70_028125	COG2390	Transcriptional regulator
N7E70_028130	COG0500	methyltransferase
N7E70_028140	COG1414	Transcriptional regulator
N7E70_028145	COG1475	DNA binding
N7E70_028150	COG1192	Involved in chromosome partitioning
N7E70_028165	COG0277	FAD linked oxidase domain protein
N7E70_028175	COG0604	alcohol dehydrogenase
N7E70_028180	COG1024	Enoyl-CoA hydratase
N7E70_028200	COG3842	ATPase activity
N7E70_028205	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_028210	COG4208	sulfate ABC transporter
N7E70_028220	COG0765	amino acid transport
N7E70_028290	COG5001	Diguanylate cyclase
N7E70_028340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7E70_028360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N7E70_028365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
N7E70_028370	COG3842	ATPase activity
N7E70_028395	COG2390	Transcriptional regulator
N7E70_028405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7E70_028415	COG3732	PTS system glucitol sorbitol-specific
N7E70_028435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7E70_028445	COG1177	transmembrane transport
N7E70_028455	COG3842	ATPase activity
N7E70_028470	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_028475	COG0022	dehydrogenase e1 component
N7E70_028475	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7E70_028480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7E70_028490	COG3608	succinylglutamate desuccinylase aspartoacylase
N7E70_028495	COG1126	abc transporter atp-binding protein
N7E70_028500	COG0765	amino acid transport
N7E70_028505	COG0765	amino acid transport
N7E70_028510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_028525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7E70_028595	COG0739	heme binding
N7E70_028595	COG0741	lytic transglycosylase activity
N7E70_028595	COG1196	nuclear chromosome segregation
N7E70_028605	COG1028	Short-chain dehydrogenase reductase Sdr
N7E70_028615	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N7E70_028635	COG1013	pyruvate-flavodoxin oxidoreductase activity
N7E70_028695	COG1349	DNA-binding transcription factor activity
N7E70_028725	COG3795	YCII-related domain
N7E70_028740	COG0583	DNA-binding transcription factor activity
N7E70_028750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7E70_028760	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_028785	COG3842	ATPase activity
N7E70_028795	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_028815	COG1840	ABC-type Fe3 transport system, periplasmic component
N7E70_028820	COG3842	ATPase activity
N7E70_028830	COG0625	glutathione transferase activity
N7E70_028840	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
N7E70_028850	COG1522	sequence-specific DNA binding
N7E70_028875	COG0531	amino acid
N7E70_028930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N7E70_028935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
N7E70_028950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7E70_028950	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7E70_028960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_028970	COG0069	glutamate synthase activity
N7E70_028975	COG2218	PFAM glutamate synthase alpha subunit domain protein
N7E70_028980	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7E70_028990	COG1215	transferase activity, transferring glycosyl groups
N7E70_029015	COG1215	transferase activity, transferring glycosyl groups
N7E70_029050	COG2379	hydroxypyruvate reductase
N7E70_029055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7E70_029060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N7E70_029065	COG0045	succinate-CoA ligase (ADP-forming) activity
N7E70_029085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_029090	COG1957	nucleoside hydrolase
N7E70_029100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N7E70_029145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N7E70_029170	COG1271	oxidase subunit
N7E70_029175	COG1294	oxidase, subunit
N7E70_029190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_029195	COG2986	histidine ammonia-lyase
N7E70_029200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7E70_029210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7E70_029240	COG1120	ATPase activity
N7E70_029245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7E70_029255	COG4206	TonB-dependent receptor
N7E70_029270	COG3483	tryptophan 2,3-dioxygenase activity
N7E70_029290	COG0411	ABC transporter
N7E70_029305	COG4120	Belongs to the binding-protein-dependent transport system permease family
N7E70_029320	COG1802	Transcriptional regulator
N7E70_029325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_029340	COG1335	isochorismatase
N7E70_029355	COG1024	Enoyl-CoA hydratase
N7E70_029360	COG1960	acyl-CoA dehydrogenase activity
N7E70_029375	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7E70_029375	COG1024	Enoyl-CoA hydratase
N7E70_029380	COG0183	Belongs to the thiolase family
N7E70_029385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_029395	COG0165	Argininosuccinate lyase
N7E70_029400	COG0395	ABC-type sugar transport system, permease component
N7E70_029405	COG1175	transmembrane transport
N7E70_029410	COG2182	Extracellular solute-binding protein
N7E70_029415	COG1940	carbohydrate kinase activity
N7E70_029430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7E70_029430	COG3453	Protein conserved in bacteria
N7E70_029440	COG1522	sequence-specific DNA binding
N7E70_029445	COG0406	alpha-ribazole phosphatase activity
N7E70_029450	COG3842	ATPase activity
N7E70_029455	COG4149	molybdate abc transporter
N7E70_029480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7E70_029485	COG1917	Cupin 2, conserved barrel domain protein
N7E70_029490	COG5285	phytanoyl-CoA dioxygenase
N7E70_029495	COG0527	aspartate kinase activity
N7E70_029500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_029505	COG0765	amino acid transport
N7E70_029510	COG0765	amino acid transport
N7E70_029515	COG1126	abc transporter atp-binding protein
N7E70_029525	COG4191	Histidine kinase
N7E70_029530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N7E70_029535	COG1802	Transcriptional regulator
N7E70_029540	COG3938	Belongs to the proline racemase family
N7E70_029545	COG1476	TRANSCRIPTIONal
N7E70_029550	COG0747	negative chemotaxis
N7E70_029555	COG0601	transmembrane transport
N7E70_029560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_029565	COG0444	Belongs to the ABC transporter superfamily
N7E70_029570	COG4608	Belongs to the ABC transporter superfamily
N7E70_029575	COG0006	proline dipeptidase activity
N7E70_029595	COG1846	Transcriptional regulator
N7E70_029615	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7E70_029620	COG3971	2-oxopent-4-enoate hydratase activity
N7E70_029630	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_029640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7E70_029645	COG0601	transmembrane transport
N7E70_029655	COG2186	Transcriptional regulator
N7E70_029685	COG2159	amidohydrolase
N7E70_029690	COG3384	dioxygenase
N7E70_029700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_029700	COG0473	3-isopropylmalate dehydrogenase activity
N7E70_029705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7E70_029715	COG1448	Aminotransferase
N7E70_029720	COG0028	Belongs to the TPP enzyme family
N7E70_029755	COG1022	Amp-dependent synthetase and ligase
N7E70_029765	COG0559	Belongs to the binding-protein-dependent transport system permease family
N7E70_029805	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N7E70_029810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7E70_029820	COG0523	cobalamin synthesis protein
N7E70_029835	COG0402	S-adenosylhomocysteine deaminase activity
N7E70_029850	COG1942	4-Oxalocrotonate Tautomerase
N7E70_029865	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N7E70_029880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_029900	COG4948	Mandelate Racemase Muconate Lactonizing
N7E70_029910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7E70_029915	COG4521	taurine ABC transporter
N7E70_029925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N7E70_029945	COG5489	Protein of unknown function (DUF736)
N7E70_029950	COG4227	nucleotidyltransferase activity
N7E70_029955	COG3831	ATPase activity
N7E70_029980	COG1475	DNA binding
N7E70_030040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N7E70_030045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7E70_030055	COG1454	alcohol dehydrogenase
N7E70_030065	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_030070	COG0318	PFAM AMP-dependent synthetase and ligase
N7E70_030075	COG0625	glutathione transferase activity
N7E70_030080	COG0277	FAD linked oxidase domain protein
N7E70_030100	COG0395	ABC-type sugar transport system, permease component
N7E70_030105	COG1175	transmembrane transport
N7E70_030110	COG1653	transport
N7E70_030115	COG3842	ATPase activity
N7E70_030120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7E70_030130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7E70_030170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_030200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7E70_030215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7E70_030225	COG0640	Transcriptional regulator
N7E70_030230	COG1475	DNA binding
N7E70_030235	COG1192	Involved in chromosome partitioning
N7E70_030245	COG3177	Filamentation induced by cAMP protein fic
N7E70_030255	COG3916	Acyl-homoserine-lactone synthase
N7E70_030260	COG4962	Type ii secretion system protein e
N7E70_030265	COG3838	Conjugal transfer protein Trbc
N7E70_030270	COG5268	conjugation
N7E70_030275	COG3451	type IV secretory pathway VirB4
N7E70_030280	COG5314	conjugation
N7E70_030290	COG3846	protein secretion by the type IV secretion system
N7E70_030295	COG3701	Conjugal transfer protein
N7E70_030365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7E70_030385	COG4959	Type IV secretory pathway protease TraF
N7E70_030390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7E70_030460	COG3701	Conjugal transfer protein
N7E70_030465	COG3846	protein secretion by the type IV secretion system
N7E70_030475	COG5314	conjugation
N7E70_030480	COG3451	type IV secretory pathway VirB4
N7E70_030490	COG3838	Conjugal transfer protein Trbc
N7E70_030495	COG4962	Type ii secretion system protein e
N7E70_030500	COG1192	Involved in chromosome partitioning
N7E70_030505	COG1475	DNA binding
N7E70_030510	COG0640	Transcriptional regulator
N7E70_030515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7E70_030530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7E70_030555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7E70_030570	COG0174	glutamine synthetase
N7E70_030575	COG1012	belongs to the aldehyde dehydrogenase family
N7E70_030585	COG1414	Transcriptional regulator
N7E70_030590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7E70_030595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7E70_030600	COG3616	Alanine racemase, N-terminal domain
N7E70_030605	COG2423	ornithine cyclodeaminase activity
N7E70_030615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7E70_030625	COG3842	ATPase activity
N7E70_030630	COG1176	ABC-type spermidine putrescine transport system, permease component I
N7E70_030645	COG2801	Transposase and inactivated derivatives
N7E70_030660	COG0028	Belongs to the TPP enzyme family
N7E70_030670	COG1271	oxidase subunit
N7E70_030675	COG1294	oxidase, subunit
N7E70_030690	COG4566	intracellular signal transduction
N7E70_030695	COG2198	Histidine kinase
N7E70_030695	COG2205	protein histidine kinase activity
N7E70_030695	COG0784	Response regulator, receiver
N7E70_030695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7E70_030735	COG1475	DNA binding
N7E70_030755	COG2824	Alkylphosphonate utilization operon protein PhnA
N7E70_030770	COG4227	nucleotidyltransferase activity
N7E70_030780	COG5489	Protein of unknown function (DUF736)
N7E70_030785	COG3831	ATPase activity
N7E70_030790	COG3505	Type IV secretory pathway VirD4