locus-tag	class	description
Adeg_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Adeg_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Adeg_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Adeg_0005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Adeg_0006	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Adeg_0007	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Adeg_0008	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Adeg_0009	ENOG4105C5R	Aminotransferase
Adeg_0011	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Adeg_0012	ENOG4105VTR	Integrase
Adeg_0024	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Adeg_0027	ENOG41080XP	Cbs domain
Adeg_0034	ENOG4107QQM	Cysteine-rich domain
Adeg_0035	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
Adeg_0036	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Adeg_0037	ENOG4105VF7	tolerance protein
Adeg_0038	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Adeg_0046	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_0047	ENOG4108ZB6	transcriptional regulator AsnC family
Adeg_0048	ENOG4105CHM	Aminotransferase
Adeg_0050	ENOG4105C75	arginyL-tRNA synthetase
Adeg_0051	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Adeg_0052	ENOG4105D07	Signal peptide peptidase, SppA
Adeg_0054	ENOG410812K	response regulator receiver protein
Adeg_0057	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Adeg_0058	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Adeg_0061	ENOG41082DI	50s ribosomal protein l31
Adeg_0062	ENOG4105CBJ	Metal-dependent enzyme
Adeg_0063	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Adeg_0064	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Adeg_0065	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Adeg_0067	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Adeg_0068	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
Adeg_0070	ENOG4108YZG	isomerase
Adeg_0071	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Adeg_0072	ENOG4107YWA	deoxycytidylate deaminase
Adeg_0074	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Adeg_0077	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
Adeg_0078	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Adeg_0079	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Adeg_0080	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Adeg_0081	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Adeg_0082	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Adeg_0083	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Adeg_0084	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Adeg_0086	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
Adeg_0087	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
Adeg_0089	ENOG4105EMN	RNA polymerase sigma factor
Adeg_0090	ENOG410838F	Glycosyl transferase family 2
Adeg_0096	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Adeg_0097	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
Adeg_0098	ENOG4107KET	secretion protein, HlyD family
Adeg_0099	ENOG4105CW7	secretion protein, HlyD family
Adeg_0100	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Adeg_0104	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Adeg_0105	ENOG4107EF8	Glycosyl transferase (Group 1
Adeg_0109	ENOG4105KME	endoribonuclease L-psp
Adeg_0111	ENOG4105HKU	nucleoside recognition domain-containing protein
Adeg_0113	ENOG4105H20	Sporulation integral membrane protein YlbJ
Adeg_0115	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Adeg_0116	ENOG4106H78	methyltransferase
Adeg_0117	ENOG4108IMY	Transcriptional regulator
Adeg_0120	ENOG4105RYY	domain protein
Adeg_0124	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
Adeg_0125	ENOG4105YWU	small acid-soluble spore protein
Adeg_0126	ENOG4105CB5	ATP-dependent DNA helicase recG
Adeg_0129	ENOG4105VCC	30S ribosomal protein S21
Adeg_0130	ENOG41068P3	sporulation protein YqfC
Adeg_0134	ENOG4105C9A	Phoh family
Adeg_0135	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Adeg_0136	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Adeg_0137	ENOG4105KG3	cytidine deaminase
Adeg_0138	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Adeg_0143	ENOG4108Z86	Glutamine amidotransferase
Adeg_0144	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Adeg_0145	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Adeg_0146	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Adeg_0147	ENOG4105K8N	protein family UPF0079, ATPase
Adeg_0148	ENOG41072GX	Peptidase M22 Glycoprotease
Adeg_0149	ENOG410801F	ribosomal-protein-alanine acetyltransferase
Adeg_0150	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Adeg_0152	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Adeg_0156	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Adeg_0157	ENOG4107QIZ	NADH dehydrogenase
Adeg_0158	ENOG4105GKE	subunit e
Adeg_0159	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Adeg_0161	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Adeg_0163	ENOG4105DZS	Phenylacetate-CoA ligase
Adeg_0166	ENOG4105DZS	Phenylacetate-CoA ligase
Adeg_0169	ENOG4105C6K	Malic enzyme
Adeg_0170	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Adeg_0171	ENOG4105D63	family UPF0324
Adeg_0172	ENOG4105BZU	Histidine kinase
Adeg_0173	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Adeg_0174	ENOG4107YZX	Universal stress protein
Adeg_0177	ENOG4105DAN	ATP-dependent protease
Adeg_0178	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Adeg_0179	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Adeg_0180	ENOG4105K46	50S ribosomal protein l27
Adeg_0181	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Adeg_0182	ENOG4105E3H	phosphoglycerate mutase
Adeg_0183	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Adeg_0185	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Adeg_0186	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Adeg_0188	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Adeg_0189	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Adeg_0190	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Adeg_0191	ENOG4105VFU	Rna-binding protein
Adeg_0193	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Adeg_0195	ENOG4105CPI	Metal Dependent Phosphohydrolase
Adeg_0198	ENOG4105DZ1	carboxypeptidase
Adeg_0204	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
Adeg_0206	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Adeg_0207	ENOG4105CYW	agmatinase
Adeg_0208	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Adeg_0209	ENOG4108JVH	Protein of unknown function DUF43
Adeg_0210	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Adeg_0211	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Adeg_0212	ENOG4108UJD	30S ribosomal protein S9
Adeg_0218	ENOG4105NBF	ammecr1 domain protein
Adeg_0221	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Adeg_0222	ENOG4105C01	Dihydroxy-acid dehydratase
Adeg_0223	ENOG4105C7K	acetolactate synthase
Adeg_0225	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Adeg_0226	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Adeg_0227	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Adeg_0228	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Adeg_0229	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Adeg_0230	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Adeg_0231	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Adeg_0232	ENOG4105WEF	catalase
Adeg_0238	ENOG4106VK6	Flagellar motor protein
Adeg_0239	ENOG4105E14	MotA TolQ exbB proton channel
Adeg_0243	ENOG4108V3W	Chemotaxis protein, CheW
Adeg_0244	ENOG4105CBS	Chea signal transduction histidine kinase
Adeg_0251	ENOG4105I03	Flagellin
Adeg_0252	ENOG4107TVC	Glycosyl transferase, family 2
Adeg_0254	ENOG4107RT6	flagellar hook-associated
Adeg_0278	ENOG4108IHU	transport system permease protein
Adeg_0281	ENOG4105E0A	ABC, transporter
Adeg_0282	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Adeg_0284	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Adeg_0287	ENOG4105CHR	reductase
Adeg_0290	ENOG4107QHI	-hydrogenase
Adeg_0291	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Adeg_0292	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
Adeg_0293	ENOG4105EKQ	RNA-directed DNA polymerase
Adeg_0294	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Adeg_0295	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Adeg_0297	ENOG4105E1K	spore germination protein
Adeg_0300	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Adeg_0301	ENOG4106DSS	Tartrate dehydratase subunit alpha
Adeg_0307	ENOG4105C83	adenylosuccinate lyase
Adeg_0308	ENOG4105C8V	SAICAR synthetase
Adeg_0310	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Adeg_0311	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Adeg_0312	ENOG4107QNG	Phosphoribosylglycinamide synthetase
Adeg_0314	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Adeg_0315	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Adeg_0316	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Adeg_0317	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Adeg_0321	ENOG4107T8Q	Glycosyl transferase (Group 1
Adeg_0323	ENOG4108NGH	radical SAM domain protein
Adeg_0331	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
Adeg_0332	ENOG4107QIZ	NADH dehydrogenase
Adeg_0335	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
Adeg_0336	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
Adeg_0337	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
Adeg_0339	ENOG41080XS	Cobyrinic acid ac-diamide synthase
Adeg_0340	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
Adeg_0341	ENOG4107VP5	methyltetrahydrofolate corrinoid iron-sulfur protein methyltransferase
Adeg_0342	ENOG4105CX0	fumarate reductase succinate dehydrogenase flavoprotein domain protein
Adeg_0347	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Adeg_0348	ENOG4105E35	Dipicolinate synthase subunit A
Adeg_0349	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
Adeg_0350	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Adeg_0351	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Adeg_0353	ENOG4108IY8	ABC, transporter
Adeg_0361	ENOG4105BZ1	(ABC) transporter
Adeg_0362	ENOG4105C7N	Xanthine uracil vitamin C permease
Adeg_0363	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_0366	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Adeg_0369	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Adeg_0370	ENOG4105CXT	aspartate transcarbamylase
Adeg_0371	ENOG4105CD3	dihydroorotase
Adeg_0372	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Adeg_0373	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Adeg_0374	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Adeg_0375	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Adeg_0376	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Adeg_0377	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Adeg_0378	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Adeg_0379	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Adeg_0380	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Adeg_0381	ENOG4105C5X	domain protein
Adeg_0384	ENOG4105CBC	glutamate synthase
Adeg_0386	ENOG4105C5F	glutamine synthetase
Adeg_0387	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
Adeg_0393	ENOG4105CSM	endonuclease III
Adeg_0394	ENOG4108UVJ	appr-1-p processing domain protein
Adeg_0395	ENOG4105BZ4	penicillin-binding protein
Adeg_0396	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Adeg_0397	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
Adeg_0399	ENOG4108VJ1	Transcriptional regulator (CarD family
Adeg_0400	ENOG4105CTP	PilT protein domain protein
Adeg_0401	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Adeg_0402	ENOG4105D7W	serine acetyltransferase
Adeg_0403	ENOG4105C8N	cysteinyl-tRNA synthetase
Adeg_0404	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Adeg_0405	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Adeg_0406	ENOG4105M0M	Tetracycline resistance protein
Adeg_0407	ENOG4105QIV	RNA polymerase
Adeg_0409	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Adeg_0419	ENOG4105VTR	Integrase
Adeg_0420	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_0421	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Adeg_0422	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
Adeg_0423	ENOG4107QI6	Cysteine desulfurase
Adeg_0424	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Adeg_0425	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Adeg_0429	ENOG4107RFW	hydrolase family 57
Adeg_0433	ENOG4107SN7	NLP P60 protein
Adeg_0434	ENOG4105C0B	DNA polymerase III (alpha subunit)
Adeg_0435	ENOG4105WP2	Tryptophan RNA-binding attenuator protein
Adeg_0438	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Adeg_0439	ENOG4105CTQ	phosphohexokinase
Adeg_0445	ENOG4105VN1	Heat shock protein
Adeg_0447	ENOG4108YZ4	nudix hydrolase
Adeg_0449	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Adeg_0451	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Adeg_0453	ENOG4105ED1	spovr family
Adeg_0454	ENOG4105E2Z	phosphate ABC transporter (Permease
Adeg_0455	ENOG4105C8U	phosphate abc transporter
Adeg_0456	ENOG4105CVA	phosphate
Adeg_0458	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Adeg_0460	ENOG4105WZB	UPF0342 protein
Adeg_0461	ENOG4105BZU	Histidine kinase
Adeg_0464	ENOG4105MS2	ribosomal subunit Interface protein
Adeg_0466	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Adeg_0469	ENOG4108HHA	Transketolase
Adeg_0470	ENOG4108IUS	Transketolase
Adeg_0471	ENOG4105CAK	Cell division ATP-binding protein ftsE
Adeg_0472	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Adeg_0473	ENOG4108K5P	(LipO)protein
Adeg_0476	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
Adeg_0477	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Adeg_0478	ENOG4105BZU	Histidine kinase
Adeg_0479	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Adeg_0481	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_0487	ENOG4108M14	stage v sporulation protein t
Adeg_0488	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Adeg_0489	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Adeg_0490	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Adeg_0492	ENOG4108IUQ	atp-dependent protease
Adeg_0493	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Adeg_0496	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Adeg_0504	ENOG4108PQP	glycosyl transferase group 1
Adeg_0506	ENOG4105MFV	ABC-2 type transporter
Adeg_0511	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_0526	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Adeg_0531	ENOG4105BZU	Histidine kinase
Adeg_0534	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Adeg_0535	ENOG41082NX	50s ribosomal protein l35
Adeg_0536	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Adeg_0540	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Adeg_0541	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Adeg_0542	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
Adeg_0544	ENOG4105CFP	Peptidase U32
Adeg_0545	ENOG4105C98	muts2 protein
Adeg_0547	ENOG4105C3K	feS assembly ATPase SufC
Adeg_0549	ENOG4105D65	subunit l
Adeg_0550	ENOG4107TDF	Formate hydrogenlyase subunit 4
Adeg_0551	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
Adeg_0552	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Adeg_0553	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Adeg_0556	ENOG4105EET	magnesium chelatase
Adeg_0557	ENOG4105CJ1	ABC, transporter
Adeg_0558	ENOG4105E3A	(ABC) transporter
Adeg_0562	ENOG4105CQB	FAD linked oxidase domain protein
Adeg_0563	ENOG4105JXH	GntR family transcriptional regulator
Adeg_0564	ENOG4105DAA	L-lactate
Adeg_0567	ENOG4105C3G	gtp-binding protein
Adeg_0568	ENOG4105D98	threonine synthase
Adeg_0569	ENOG4108ZCF	integral membrane protein
Adeg_0570	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Adeg_0572	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Adeg_0573	ENOG4108FW6	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Adeg_0574	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Adeg_0576	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Adeg_0577	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Adeg_0578	ENOG4105CE9	30S ribosomal protein S2
Adeg_0579	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Adeg_0580	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Adeg_0581	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Adeg_0584	ENOG4105KNE	Phosphatidate cytidylyltransferase
Adeg_0585	ENOG4105C02	permease
Adeg_0586	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Adeg_0587	ENOG4105DZP	Membrane-associated zinc metalloprotease
Adeg_0588	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Adeg_0589	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Adeg_0591	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Adeg_0593	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Adeg_0594	ENOG4105EUJ	GTP cyclohydrolase i
Adeg_0595	ENOG4105YAC	
Adeg_0596	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Adeg_0597	ENOG4105XEW	small acid-soluble spore protein
Adeg_0598	ENOG4105CKP	Polysaccharide Biosynthesis Protein
Adeg_0601	ENOG4108ZRV	stage ii sporulation protein p
Adeg_0602	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Adeg_0603	ENOG4105CSA	Coproporphyrinogen iii oxidase
Adeg_0604	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Adeg_0607	ENOG4105CFG	Acts as a chaperone (By similarity)
Adeg_0608	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Adeg_0609	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Adeg_0610	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Adeg_0611	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Adeg_0612	ENOG4105MCT	stage V sporulation protein S
Adeg_0613	ENOG4108K4H	
Adeg_0614	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
Adeg_0616	ENOG4107BJW	polysaccharide deacetylase
Adeg_0620	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Adeg_0621	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Adeg_0622	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Adeg_0625	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Adeg_0626	ENOG4105CEV	competence damage-inducible protein
Adeg_0628	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Adeg_0631	ENOG4107YZX	Universal stress protein
Adeg_0633	ENOG4105CE1	Ferrous iron transport protein b
Adeg_0635	ENOG4105CE1	Ferrous iron transport protein b
Adeg_0639	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Adeg_0640	ENOG41066FR	extracellular solute-binding protein
Adeg_0641	ENOG4105E0C	molybdate abc transporter
Adeg_0642	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Adeg_0643	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_0644	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Adeg_0645	ENOG4105BZU	Histidine kinase
Adeg_0646	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
Adeg_0647	ENOG4108ZJ4	polysaccharide deacetylase
Adeg_0651	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
Adeg_0655	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
Adeg_0656	ENOG4105E2X	shikimate dehydrogenase
Adeg_0657	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Adeg_0658	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Adeg_0659	ENOG4105D49	3-dehydroquinate synthase
Adeg_0660	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Adeg_0661	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Adeg_0662	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Adeg_0663	ENOG4105DC7	peptidase M24
Adeg_0664	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Adeg_0665	ENOG4107NFR	Fructose-1,6-bisphosphatase
Adeg_0666	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Adeg_0668	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Adeg_0669	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Adeg_0670	ENOG4105EV6	Pfam:DUF178
Adeg_0671	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Adeg_0672	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
Adeg_0673	ENOG4105EM7	Selenocysteine-specific translation elongation factor
Adeg_0681	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Adeg_0688	ENOG4108UUM	single-stranded DNA-binding protein
Adeg_0693	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Adeg_0697	ENOG4108IMY	Transcriptional regulator
Adeg_0712	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Adeg_0740	ENOG4105BZU	Histidine kinase
Adeg_0751	ENOG4105BZU	Histidine kinase
Adeg_0763	ENOG4105CND	Glycosyl transferase, family 2
Adeg_0791	ENOG4106A3R	peptidase
Adeg_0797	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Adeg_0831	ENOG4105VTR	Integrase
Adeg_0839	ENOG4105KC4	UPF0296 protein
Adeg_0840	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Adeg_0845	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Adeg_0847	ENOG4105CND	Glycosyl transferase, family 2
Adeg_0853	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Adeg_0856	ENOG4105C25	Primosomal protein n'
Adeg_0857	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Adeg_0858	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Adeg_0859	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Adeg_0860	ENOG4105DZ1	carboxypeptidase
Adeg_0862	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
Adeg_0863	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Adeg_0864	ENOG4105PXI	polysaccharide deacetylase
Adeg_0868	ENOG4108NMV	polysaccharide deacetylase
Adeg_0869	ENOG4105DZ1	carboxypeptidase
Adeg_0882	ENOG4105D6E	homoserine dehydrogenase
Adeg_0883	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Adeg_0884	ENOG4105CFH	Aspartokinase
Adeg_0886	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Adeg_0887	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Adeg_0889	ENOG41083MR	nifu domain-containing protein
Adeg_0892	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Adeg_0898	ENOG4108NEV	two component transcriptional regulator, LytTR family
Adeg_0899	ENOG4108HRK	Histidine kinase
Adeg_0902	ENOG4107Y7Q	pfkb domain protein
Adeg_0903	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Adeg_0904	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Adeg_0909	ENOG4105CVN	desaturase
Adeg_0915	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Adeg_0919	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Adeg_0920	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
Adeg_0921	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Adeg_0922	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Adeg_0923	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Adeg_0927	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Adeg_0930	ENOG4108JJB	ABC transporter
Adeg_0931	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Adeg_0932	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
Adeg_0933	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Adeg_0934	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Adeg_0935	ENOG4108P62	biosynthesis protein (CbiG)
Adeg_0936	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Adeg_0937	ENOG4108JTQ	reductase
Adeg_0940	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
Adeg_0941	ENOG4105F7J	membrane-bound serine protease
Adeg_0942	ENOG4107QX8	SPFH domain, Band 7 family protein
Adeg_0944	ENOG4105VCQ	rubredoxin
Adeg_0945	ENOG4105MAX	Superoxide reductase
Adeg_0947	ENOG4108SVB	resolvase
Adeg_0952	ENOG41067VY	50S ribosomal protein L32
Adeg_0955	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Adeg_0956	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Adeg_0957	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Adeg_0958	ENOG4105CHR	reductase
Adeg_0959	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Adeg_0960	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Adeg_0961	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Adeg_0962	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Adeg_0963	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Adeg_0964	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Adeg_0965	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Adeg_0967	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Adeg_0968	ENOG4105DR4	Methyltransferase
Adeg_0991	ENOG4107ZYJ	bioY protein
Adeg_0994	ENOG4108W9H	Tetr family transcriptional regulator
Adeg_0996	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
Adeg_0999	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
Adeg_1001	ENOG4105CVN	desaturase
Adeg_1004	ENOG4105DU1	integral membrane protein, terc
Adeg_1008	ENOG4105D06	uba thif-type nad fad binding protein
Adeg_1009	ENOG4105DGU	Histone deacetylase
Adeg_1010	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Adeg_1011	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Adeg_1012	ENOG4105BZU	Histidine kinase
Adeg_1013	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Adeg_1014	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Adeg_1015	ENOG4105DFA	alanine racemase domain protein
Adeg_1016	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Adeg_1018	ENOG41067XK	integral membrane protein
Adeg_1019	ENOG4105VZ9	UPF0235 protein
Adeg_1020	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Adeg_1021	ENOG4105E4C	Lytic transglycosylase catalytic
Adeg_1022	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Adeg_1023	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Adeg_1027	ENOG4105BZU	Histidine kinase
Adeg_1028	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Adeg_1030	ENOG4107T5V	SNARE associated Golgi
Adeg_1032	ENOG4105BZF	Glycosyl transferase (Group 1
Adeg_1040	ENOG4105WH1	Two component transcriptional regulator luxr family
Adeg_1046	ENOG4105C0A	alcohol dehydrogenase
Adeg_1048	ENOG4108WZW	RNA polymerase sigma
Adeg_1070	ENOG4105EKQ	RNA-directed DNA polymerase
Adeg_1071	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Adeg_1073	ENOG4105CYN	Serine protein kinase
Adeg_1076	ENOG4105MYT	Heat shock protein
Adeg_1082	ENOG4105D0M	Protease HtpX homolog
Adeg_1089	ENOG4105D1F	ATP-binding protein
Adeg_1090	ENOG4107U53	septum site-determining protein minD
Adeg_1094	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Adeg_1095	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Adeg_1096	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Adeg_1097	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Adeg_1099	ENOG4107SDT	Homocitrate synthase
Adeg_1100	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Adeg_1101	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Adeg_1102	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Adeg_1103	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Adeg_1106	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Adeg_1107	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Adeg_1108	ENOG4105CPF	Cell wall formation (By similarity)
Adeg_1109	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Adeg_1121	ENOG4105NTW	Transcriptional regulator
Adeg_1122	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Adeg_1126	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Adeg_1128	ENOG4107TVC	Glycosyl transferase, family 2
Adeg_1131	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
Adeg_1136	ENOG4105CN5	Metallo-Beta-Lactamase
Adeg_1137	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Adeg_1139	ENOG4105CE1	Ferrous iron transport protein b
Adeg_1146	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Adeg_1147	ENOG4105F6E	Acyl-transferase
Adeg_1148	ENOG4105CAT	Cytidine monophosphate kinase
Adeg_1149	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Adeg_1153	ENOG4105CQC	Prephenate dehydratase
Adeg_1154	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Adeg_1155	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Adeg_1156	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Adeg_1157	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Adeg_1158	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Adeg_1159	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Adeg_1160	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Adeg_1161	ENOG4105DDQ	anthranilate synthase
Adeg_1162	ENOG4105CRQ	synthase (Component I)
Adeg_1163	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_1170	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Adeg_1171	ENOG4105EWC	Purine nucleoside phosphorylase
Adeg_1188	ENOG4105D63	family UPF0324
Adeg_1193	ENOG4105E0A	ABC, transporter
Adeg_1194	ENOG4105EHG	Permease protein
Adeg_1198	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
Adeg_1199	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Adeg_1201	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Adeg_1204	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Adeg_1205	ENOG4108JJB	ABC transporter
Adeg_1207	ENOG4107S91	Sodium hydrogen exchanger
Adeg_1209	ENOG4105CE1	Ferrous iron transport protein b
Adeg_1211	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Adeg_1214	ENOG4105FDK	ABC transporter
Adeg_1215	ENOG4105DSE	periplasmic solute binding protein
Adeg_1216	ENOG4105I3K	Ferric uptake regulator, Fur family
Adeg_1220	ENOG4105F8V	Hydrolase, tatD family
Adeg_1222	ENOG4107QZF	nitrite reductase NADPH large subunit
Adeg_1223	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Adeg_1224	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Adeg_1228	ENOG4105C8Q	Methyl-accepting chemotaxis
Adeg_1229	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Adeg_1230	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Adeg_1231	ENOG4105DPX	Hydrogenase, large subunit
Adeg_1232	ENOG4105E3S	small subunit
Adeg_1233	ENOG4108USZ	hydrogenase
Adeg_1234	ENOG4105CTQ	phosphohexokinase
Adeg_1237	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Adeg_1240	ENOG4108IJ0	Aspartate ammonia-lyase
Adeg_1243	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Adeg_1244	ENOG4107QW8	radical SAM domain protein
Adeg_1247	ENOG4105CZ3	stage V sporulation protein ad
Adeg_1248	ENOG41090VF	Stage v sporulation protein ac
Adeg_1251	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Adeg_1253	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Adeg_1254	ENOG4108UMR	transcriptional regulator AsnC family
Adeg_1255	ENOG4108ZGY	Transcriptional regulator (AsnC family)
Adeg_1256	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Adeg_1257	ENOG4105D52	delta-aminolevulinic acid dehydratase
Adeg_1259	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Adeg_1260	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Adeg_1261	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Adeg_1263	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Adeg_1266	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
Adeg_1267	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Adeg_1269	ENOG4105CAG	UPF0210 protein
Adeg_1270	ENOG4105VUC	UPF0237 protein
Adeg_1271	ENOG4107WK9	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Adeg_1272	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Adeg_1274	ENOG4105VIE	preprotein translocase, subunit YajC
Adeg_1275	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Adeg_1278	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Adeg_1279	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Adeg_1282	ENOG4105VBF	alkaline shock protein
Adeg_1283	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Adeg_1284	ENOG4107QSA	Oxaloacetate decarboxylase
Adeg_1287	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Adeg_1290	ENOG4105KHN	chorismate mutase
Adeg_1292	ENOG4105FE9	pseudouridine synthase
Adeg_1294	ENOG4105E4C	Lytic transglycosylase catalytic
Adeg_1295	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Adeg_1296	ENOG4108JIC	nucleoside recognition domain protein
Adeg_1297	ENOG4105KBJ	sporulation protein ytfj
Adeg_1300	ENOG4105C31	Tryptophanyl-tRNA synthetase
Adeg_1301	ENOG4108Z4T	Peptidase M50
Adeg_1303	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Adeg_1306	ENOG4105BZU	Histidine kinase
Adeg_1308	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
Adeg_1309	ENOG4105DJV	ribulose-phosphate 3-epimerase
Adeg_1310	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Adeg_1311	ENOG4105D9P	serine threonine protein kinase
Adeg_1312	ENOG4108ZF3	Phosphatase
Adeg_1313	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Adeg_1319	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Adeg_1324	ENOG4105F23	Fibronectin-binding protein
Adeg_1326	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
Adeg_1329	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
Adeg_1334	ENOG41086B8	CoB-CoM heterodisulfide reductase
Adeg_1336	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
Adeg_1345	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
Adeg_1356	ENOG4105BZU	Histidine kinase
Adeg_1370	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Adeg_1379	ENOG4105D3R	alkyl hydroperoxide reductase
Adeg_1381	ENOG4105CHM	Aminotransferase
Adeg_1382	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Adeg_1389	ENOG4105CKK	Glycosyl transferase, family 2
Adeg_1392	ENOG4107QQR	Sporulation
Adeg_1393	ENOG4105S1Z	Stage IV sporulation protein B
Adeg_1394	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Adeg_1395	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Adeg_1396	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Adeg_1397	ENOG4105DX0	Hemolysin A
Adeg_1398	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Adeg_1401	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
Adeg_1402	ENOG4105VYW	UPF0251 protein
Adeg_1406	ENOG4105VFF	UPF0102 protein
Adeg_1407	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Adeg_1408	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Adeg_1409	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Adeg_1411	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Adeg_1412	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Adeg_1413	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Adeg_1416	ENOG4105K5M	30s ribosomal protein S16
Adeg_1418	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
Adeg_1429	ENOG4107QZF	nitrite reductase NADPH large subunit
Adeg_1431	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Adeg_1434	ENOG4105CJN	penicillin-binding protein
Adeg_1435	ENOG4105HHA	aminodeoxychorismate lyase
Adeg_1436	ENOG41073R8	VanW family
Adeg_1437	ENOG41085AS	UPF0473 protein
Adeg_1438	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Adeg_1439	ENOG4105VBH	UPF0297 protein
Adeg_1440	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Adeg_1445	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Adeg_1446	ENOG41065RQ	ADP-ribosylation crystallin J1
Adeg_1449	ENOG4108SVB	resolvase
Adeg_1450	ENOG4105DVY	radical SAM domain protein
Adeg_1451	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Adeg_1452	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Adeg_1453	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Adeg_1455	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Adeg_1464	ENOG4105D8X	mechanosensitive ion channel
Adeg_1466	ENOG4107QZB	decarboxylase
Adeg_1467	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Adeg_1468	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Adeg_1472	ENOG4108IGT	Dipeptidase
Adeg_1473	ENOG4105MCT	stage V sporulation protein S
Adeg_1474	ENOG4105D48	metallophosphoesterase
Adeg_1475	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Adeg_1476	ENOG4105BZU	Histidine kinase
Adeg_1477	ENOG4105CPK	Glycosyl transferase (Group 1
Adeg_1481	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Adeg_1483	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Adeg_1485	ENOG4108QG2	Membrane
Adeg_1487	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Adeg_1488	ENOG4105C0Z	ABC transporter
Adeg_1489	ENOG4108IV0	ABC, transporter
Adeg_1490	ENOG4105CP9	extracellular ligand-binding receptor
Adeg_1493	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Adeg_1494	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Adeg_1495	ENOG4108ZT0	50S ribosomal protein l17
Adeg_1496	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Adeg_1497	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Adeg_1498	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Adeg_1499	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Adeg_1500	ENOG41067V7	50S ribosomal protein L36
Adeg_1501	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Adeg_1503	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Adeg_1504	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Adeg_1505	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Adeg_1506	ENOG4105VPB	50S ribosomal protein L30
Adeg_1507	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Adeg_1508	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Adeg_1509	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Adeg_1510	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Adeg_1511	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Adeg_1512	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Adeg_1513	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Adeg_1514	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Adeg_1515	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Adeg_1516	ENOG41082SA	50s ribosomal protein l29
Adeg_1517	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Adeg_1518	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Adeg_1519	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Adeg_1520	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Adeg_1521	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Adeg_1522	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Adeg_1523	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Adeg_1524	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Adeg_1525	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Adeg_1526	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Adeg_1527	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Adeg_1528	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Adeg_1529	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Adeg_1531	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Adeg_1532	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Adeg_1533	ENOG41083CN	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Adeg_1534	ENOG4107QMS	site-determining protein
Adeg_1535	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Adeg_1536	ENOG4105G5W	regulator Fur family
Adeg_1540	ENOG4105DFF	Rod shape-determining protein mreb
Adeg_1541	ENOG4105W5Q	DNA repair protein (RadC
Adeg_1542	ENOG4108Z03	MAF-like protein
Adeg_1547	ENOG4105F1A	Pyruvate formate-lyase
Adeg_1548	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Adeg_1549	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Adeg_1550	ENOG4105WR5	sporulation protein, YlmC YmxH family
Adeg_1551	ENOG4108ZXQ	stage ii sporulation protein r
Adeg_1552	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Adeg_1553	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Adeg_1554	ENOG4108AWX	Sporulation factor SpoIIGA 
Adeg_1555	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Adeg_1556	ENOG4105K67	small basic protein
Adeg_1561	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Adeg_1562	ENOG4105D4A	Cell wall formation (By similarity)
Adeg_1563	ENOG4105DFU	Cell wall formation (By similarity)
Adeg_1564	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Adeg_1565	ENOG4105CNI	cell division protein FtsW
Adeg_1566	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Adeg_1567	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Adeg_1569	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Adeg_1570	ENOG4105CJN	penicillin-binding protein
Adeg_1572	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Adeg_1573	ENOG4108V6E	Cell division protein mraZ
Adeg_1576	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Adeg_1581	ENOG4105E63	Pfam:DUF178
Adeg_1582	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Adeg_1584	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Adeg_1585	ENOG4107YZX	Universal stress protein
Adeg_1590	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Adeg_1593	ENOG4108IV0	ABC, transporter
Adeg_1594	ENOG4105CP9	extracellular ligand-binding receptor
Adeg_1596	ENOG4105C32	Amino acid ABC transporter (Permease)
Adeg_1597	ENOG4108IQE	Amp-dependent synthetase and ligase
Adeg_1598	ENOG4105C0Z	ABC transporter
Adeg_1600	ENOG4105E3H	phosphoglycerate mutase
Adeg_1602	ENOG4107RCC	Major Facilitator Superfamily
Adeg_1604	ENOG4105C34	Pseudouridine synthase
Adeg_1605	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Adeg_1609	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Adeg_1610	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Adeg_1611	ENOG4105CNI	cell division protein FtsW
Adeg_1612	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Adeg_1613	ENOG4105XZU	Preprotein translocase, subunit SecG
Adeg_1614	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Adeg_1615	ENOG4105CP7	Triose-phosphate isomerase
Adeg_1616	ENOG4105BZA	Phosphoglycerate kinase
Adeg_1618	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Adeg_1619	ENOG4105CIE	May be required for sporulation (By similarity)
Adeg_1620	ENOG4107BJW	polysaccharide deacetylase
Adeg_1621	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Adeg_1622	ENOG4107QYV	phosphohexose isomerase
Adeg_1623	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Adeg_1624	ENOG4105BZU	Histidine kinase
Adeg_1625	ENOG4108ISE	4Fe-4S ferredoxin, iron-sulfur binding
Adeg_1626	ENOG4105K4H	Nlp p60 protein
Adeg_1627	ENOG4105JFG	SpoIID LytB domain protein
Adeg_1628	ENOG41061AI	Protein of unknown function (DUF2905)
Adeg_1629	ENOG4105WPN	DNA integration recombination invertion protein
Adeg_1630	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Adeg_1631	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Adeg_1632	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Adeg_1634	ENOG4105CDY	transcriptional regulatory protein
Adeg_1635	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
Adeg_1638	ENOG4105EHG	Permease protein
Adeg_1642	ENOG4105E0A	ABC, transporter
Adeg_1644	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Adeg_1645	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Adeg_1646	ENOG4105CTK	cobaltochelatase, cobn subunit
Adeg_1647	ENOG4105CRK	lysyL-tRNA synthetase
Adeg_1648	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Adeg_1649	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Adeg_1652	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Adeg_1653	ENOG4105C1V	Peptidase, M16
Adeg_1656	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Adeg_1657	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Adeg_1658	ENOG4105DTN	riboflavin biosynthesis protein ribF
Adeg_1659	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Adeg_1661	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Adeg_1662	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Adeg_1664	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
Adeg_1665	ENOG4105CHV	Transcription elongation factor NusA
Adeg_1666	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Adeg_1667	ENOG4105K63	Thioredoxin
Adeg_1668	ENOG4108IMY	Transcriptional regulator
Adeg_1669	ENOG4105C22	threonyL-tRNA synthetase
Adeg_1670	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Adeg_1671	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Adeg_1673	ENOG4105C9M	aspartyl-trna synthetase
Adeg_1674	ENOG4105CUT	histidyl-tRNA synthetase
Adeg_1676	ENOG4105ECP	epimerase
Adeg_1678	ENOG4105CN5	Metallo-Beta-Lactamase
Adeg_1683	ENOG4105KQ4	Stage iii sporulation protein ad
Adeg_1684	ENOG4108CQH	stage III sporulation protein AC
Adeg_1686	ENOG4105CD2	stage iii sporulation protein aa
Adeg_1690	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Adeg_1695	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Adeg_1696	ENOG4105BZ4	penicillin-binding protein
Adeg_1697	ENOG4105DP4	dak2 domain fusion protein ylov
Adeg_1698	ENOG4105EPR	degv family
Adeg_1700	ENOG4105CD5	CoA-binding domain protein
Adeg_1701	ENOG4105F0V	Cell wall hydrolase
Adeg_1704	ENOG4108YZT	Adenosylcobinamide kinase
Adeg_1709	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Adeg_1712	ENOG4107RIQ	Sulfate adenylate transferase
Adeg_1722	ENOG4105X0D	Fimbrial protein
Adeg_1724	ENOG4105CZX	twitching motility protein
Adeg_1725	ENOG4107QHF	type ii secretion system protein e
Adeg_1726	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Adeg_1727	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Adeg_1728	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Adeg_1729	ENOG41081HM	2'-5' rna ligase
Adeg_1731	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Adeg_1733	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Adeg_1734	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Adeg_1735	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
Adeg_1737	ENOG4105HEE	Binding Domain protein
Adeg_1742	ENOG4108RC0	Electron transport protein
Adeg_1743	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Adeg_1744	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Adeg_1747	ENOG4105VPX	protein, conserved in bacteria
Adeg_1755	ENOG4105K4H	Nlp p60 protein
Adeg_1756	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Adeg_1758	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Adeg_1759	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Adeg_1760	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Adeg_1761	ENOG4105DY9	regulatoR
Adeg_1762	ENOG4108HRK	Histidine kinase
Adeg_1763	ENOG4105C59	p-type ATPase
Adeg_1766	ENOG4105V0P	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Adeg_1767	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Adeg_1778	ENOG4105D29	Helix-turn-helix type 11 domain protein
Adeg_1780	ENOG4105WEF	catalase
Adeg_1781	ENOG4107QHI	-hydrogenase
Adeg_1783	ENOG4107QHI	-hydrogenase
Adeg_1784	ENOG4107QIZ	NADH dehydrogenase
Adeg_1787	ENOG4105DPX	Hydrogenase, large subunit
Adeg_1792	ENOG4105DCG	PHP domain protein
Adeg_1795	ENOG4105C6X	Major Facilitator
Adeg_1796	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Adeg_1798	ENOG4105DZS	Phenylacetate-CoA ligase
Adeg_1804	ENOG4105C8T	Leucyl-tRNA synthetase
Adeg_1809	ENOG4105CBS	Chea signal transduction histidine kinase
Adeg_1810	ENOG4107MMM	Anti-sigma-factor antagonist
Adeg_1811	ENOG4105FUA	antagonist
Adeg_1818	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Adeg_1821	ENOG4105DKQ	ROK family
Adeg_1822	ENOG410667J	hydrolase
Adeg_1823	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Adeg_1824	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Adeg_1825	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Adeg_1827	ENOG4105CH7	arginosuccinase
Adeg_1828	ENOG4105CDH	Citrulline--aspartate ligase
Adeg_1829	ENOG4105DBV	ornithine carbamoyltransferase
Adeg_1830	ENOG4105C8Y	Acetylornithine aminotransferase
Adeg_1831	ENOG4105CAS	nag kinase
Adeg_1832	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Adeg_1833	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Adeg_1835	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Adeg_1837	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_1845	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Adeg_1846	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Adeg_1850	ENOG4107QN1	sodium solute
Adeg_1852	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Adeg_1853	ENOG4105C3M	thioredoxin reductase
Adeg_1855	ENOG4107HP6	Transcriptional regulator
Adeg_1858	ENOG4105DJV	ribulose-phosphate 3-epimerase
Adeg_1859	ENOG4107NFR	Fructose-1,6-bisphosphatase
Adeg_1860	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Adeg_1861	ENOG4108HHA	Transketolase
Adeg_1863	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Adeg_1864	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Adeg_1868	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Adeg_1872	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Adeg_1873	ENOG4108IYU	L-aspartate oxidase
Adeg_1874	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Adeg_1875	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Adeg_1876	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Adeg_1877	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Adeg_1879	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Adeg_1880	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Adeg_1881	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Adeg_1882	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Adeg_1883	ENOG4105EEI	dihydropteroate synthase
Adeg_1884	ENOG4107QQM	Cysteine-rich domain
Adeg_1888	ENOG4108YZA	Nitrogen regulatory protein pii
Adeg_1889	ENOG4105BZU	Histidine kinase
Adeg_1891	ENOG4105C5F	glutamine synthetase
Adeg_1892	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
Adeg_1893	ENOG4108W6G	cytochrome C
Adeg_1894	ENOG4105CRE	cytochrome C
Adeg_1895	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Adeg_1897	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Adeg_1898	ENOG4105BZU	Histidine kinase
Adeg_1903	ENOG4108JIG	Anaerobic dehydrogenase
Adeg_1904	ENOG4105HEE	Binding Domain protein
Adeg_1905	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Adeg_1909	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
Adeg_1912	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Adeg_1915	ENOG4105EKQ	RNA-directed DNA polymerase
Adeg_1916	ENOG4108BSC	Methyltransferase
Adeg_1917	ENOG41067VP	Protein of unknown function (DUF1049)
Adeg_1919	ENOG4105C3M	thioredoxin reductase
Adeg_1920	ENOG4105CXI	aluminum resistance protein
Adeg_1921	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Adeg_1922	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Adeg_1923	ENOG4107YX5	Pfam:DUF548
Adeg_1924	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Adeg_1925	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Adeg_1926	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Adeg_1927	ENOG4108VZM	50s ribosomal protein L10
Adeg_1928	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Adeg_1929	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Adeg_1930	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Adeg_1932	ENOG4105WDJ	50S ribosomal protein L33
Adeg_1934	ENOG4108UXE	Protein tyrosine phosphatase
Adeg_1937	ENOG4105D6J	arsenicaL-resistance protein
Adeg_1940	ENOG41082YX	Transcriptional regulator, arsr family
Adeg_1941	ENOG4107YU2	histidine triad (hIT) protein
Adeg_1942	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Adeg_1944	ENOG4105CNU	cell division protein FtsK
Adeg_1949	ENOG41066A3	ATP guanido phosphotransferase
Adeg_1950	ENOG4108Z0C	Uvrb UvrC protein
Adeg_1952	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Adeg_1953	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Adeg_1955	ENOG4105IJJ	transcriptional regulator, crp fnr family
Adeg_1959	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
Adeg_1960	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
Adeg_1961	ENOG4108YZP	cobalt ABC transporter, inner membrane subunit CbiQ
Adeg_1962	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Adeg_1963	ENOG4105EC8	Methyl-accepting chemotaxis
Adeg_1966	ENOG4105CJR	Integral membrane protein (MviN
Adeg_1968	ENOG4108QY0	Membrane
Adeg_1969	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Adeg_1970	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Adeg_1971	ENOG4105ESV	Glycosyl transferase, family 4
Adeg_1972	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Adeg_1973	ENOG4108RCF	TRANSCRIPTIONal
Adeg_1977	ENOG4105CIZ	coA-substrate-specific enzyme activase
Adeg_1978	ENOG4105VB9	50S ribosomal protein l28
Adeg_1979	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Adeg_1980	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Adeg_1981	ENOG4108R6K	riboflavin synthase, subunit alpha
Adeg_1982	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Adeg_1983	ENOG4107RBB	ABC transporter, permease
Adeg_1984	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Adeg_1985	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Adeg_1989	ENOG41082BM	Transcriptional regulator, arsr family
Adeg_1993	ENOG4108K9K	Uncharacterised protein family (UPF0236)
Adeg_2007	ENOG4105CQS	hydrogenase expression formation protein HypD
Adeg_2008	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
Adeg_2010	ENOG4107RSS	Hydrogenase accessory protein HypB
Adeg_2011	ENOG41082RJ	Hydrogenase nickel insertion protein HypA
Adeg_2017	ENOG4105DD5	Flagellar motor switch protein
Adeg_2018	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Adeg_2019	ENOG4107YTP	response regulator receiver protein
Adeg_2021	ENOG4105BZU	Histidine kinase
Adeg_2022	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Adeg_2023	ENOG4105CGA	flagellar basal-body rod protein FlgG
Adeg_2025	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Adeg_2028	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Adeg_2029	ENOG4105D7B	Flagellar biosynthesis protein flha
Adeg_2030	ENOG4105D00	flagellar biosynthetic protein flhB
Adeg_2031	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Adeg_2032	ENOG4105VS8	Flagellar biosynthetic protein fliq
Adeg_2033	ENOG4105CN7	Flagellar biosynthetic protein FliP
Adeg_2035	ENOG4105DD5	Flagellar motor switch protein
Adeg_2037	ENOG4108JQA	flagellar
Adeg_2043	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Adeg_2044	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Adeg_2045	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Adeg_2046	ENOG4108ZC9	flagellar basal-body rod protein flgc
Adeg_2047	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Adeg_2049	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Adeg_2051	ENOG4105BZU	Histidine kinase
Adeg_2053	ENOG4107R0W	ABC transporter
Adeg_2054	ENOG4105E5Q	amino acid AbC transporter
Adeg_2055	ENOG4105CDA	abc transporter atp-binding protein
Adeg_2057	ENOG4105CKU	formyltetrahydrofolate synthetase
Adeg_2058	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Adeg_2059	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Adeg_2060	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Adeg_2063	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Adeg_2067	ENOG4105VYY	sporulation protein yabp
Adeg_2069	ENOG4105K70	DNA-binding protein
Adeg_2070	ENOG4108IY2	MazG family
Adeg_2071	ENOG4108M14	stage v sporulation protein t
Adeg_2072	ENOG4108JA2	transcriptioN-repair coupling factor
Adeg_2073	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Adeg_2074	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Adeg_2075	ENOG4105CRE	cytochrome C
Adeg_2078	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Adeg_2079	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Adeg_2080	ENOG4105DUM	transcriptional regulator, lysR family
Adeg_2081	ENOG4105CUC	YeeE YedE family protein
Adeg_2082	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Adeg_2092	ENOG4105Z0W	Dissimilatory sulfite reductase D
Adeg_2093	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
Adeg_2094	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
Adeg_2095	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Adeg_2096	ENOG4105DRR	Transcriptional regulator, GntR family
Adeg_2097	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Adeg_2108	ENOG4105XFA	sporulation peptidase YabG
Adeg_2110	ENOG4108XRC	Protein of unknown function (DUF458) 
Adeg_2111	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Adeg_2112	ENOG41069ER	domain protein
Adeg_2113	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Adeg_2114	ENOG4105F8V	Hydrolase, tatD family
Adeg_2115	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Adeg_2116	ENOG4105KRN	Transcriptional regulator, abrb family
Adeg_2118	ENOG4105MA4	psp1 domain protein
Adeg_2120	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Adeg_2121	ENOG4105CXN	decarboxylase
Adeg_2125	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Adeg_2128	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Adeg_2129	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Adeg_2130	ENOG4105C6E	dna polymerase iii
Adeg_2131	ENOG4108Z6B	deaminase
Adeg_2132	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Adeg_2133	ENOG4105DZ0	fad dependent oxidoreductase
Adeg_2134	ENOG4105CDU	Replicative dna helicase
Adeg_2135	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Adeg_2136	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Adeg_2137	ENOG4108UUM	single-stranded DNA-binding protein
Adeg_2138	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Adeg_2141	ENOG4108ZDA	Sporulation protein YyaC
Adeg_2145	ENOG4105FA0	parb-like partition protein
Adeg_2146	ENOG4107QJE	Chromosome Partitioning Protein
Adeg_2147	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Adeg_2148	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
Adeg_2149	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Adeg_2150	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Adeg_2151	ENOG410886K	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Adeg_2179	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)