locus-tag	class	description
A4R43_00015	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
A4R43_00025	ENOG4107S1E	Beta-lactamase
A4R43_00045	ENOG4108KQ5	Integrase catalytic subunit
A4R43_00055	ENOG4107HP6	Transcriptional regulator
A4R43_00085	ENOG4105JZI	cytochrome P450
A4R43_00100	ENOG4105EJ2	Transcriptional regulator
A4R43_00110	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A4R43_00115	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A4R43_00160	ENOG4105CHP	RNA polymerase
A4R43_00185	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A4R43_00205	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_00230	ENOG4108PGP	mmge prpd family protein
A4R43_00240	ENOG4105CI0	Citrate lyase
A4R43_00245	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A4R43_00255	ENOG4105C32	Amino acid ABC transporter (Permease)
A4R43_00265	ENOG4105C0Z	ABC transporter
A4R43_00270	ENOG4108IV0	ABC, transporter
A4R43_00290	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
A4R43_00305	ENOG4105EA8	2-Nitropropane dioxygenase
A4R43_00310	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_00315	ENOG4105E39	Enoyl-CoA hydratase
A4R43_00325	ENOG4105E39	Enoyl-CoA hydratase
A4R43_00330	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A4R43_00340	ENOG4105CSP	Major Facilitator Superfamily
A4R43_00345	ENOG4105F44	Two component transcriptional regulator, winged helix family
A4R43_00350	ENOG4106F60	Histidine kinase
A4R43_00405	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A4R43_00425	ENOG4108WYP	Transcriptional regulator
A4R43_00435	ENOG4105CMT	Dihydroxyacetone kinase
A4R43_00440	ENOG4107YVI	ribose 5-phosphate isomerase
A4R43_00445	ENOG4108MKX	Triose-phosphate isomerase
A4R43_00465	ENOG4105C5Q	Transcriptional regulator
A4R43_00565	ENOG4105BZU	Histidine kinase
A4R43_00570	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
A4R43_00575	ENOG4105C85	amino acid
A4R43_00620	ENOG4105EEQ	Na H antiporter
A4R43_00630	ENOG4108KPJ	rna polymerase sigma factor
A4R43_00635	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A4R43_00650	ENOG4108Z6Z	Transcriptional regulator
A4R43_00655	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A4R43_00715	ENOG4105EFZ	amidohydrolase
A4R43_00785	ENOG4107SCK	Monooxygenase
A4R43_00855	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_00865	ENOG4108Q50	Histidine kinase
A4R43_00875	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
A4R43_00885	ENOG4105CHC	glucokinase (EC 2.7.1.2)
A4R43_00920	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A4R43_00930	ENOG4105ECQ	AraC Family Transcriptional Regulator
A4R43_00980	ENOG4108Z5V	transcriptional regulator, merr family
A4R43_00985	ENOG4107RSM	transcriptional regulator
A4R43_01030	ENOG4108NF7	phage-type endonuclease
A4R43_01035	ENOG4108PNI	recT protein
A4R43_01295	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A4R43_01340	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A4R43_01345	ENOG4108XHQ	(2Fe-2S)-binding domain protein
A4R43_01375	ENOG4105R1U	AraC Family Transcriptional Regulator
A4R43_01380	ENOG4105EU0	Major facilitator Superfamily
A4R43_01390	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A4R43_01480	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A4R43_01500	ENOG4105FQP	Beta-lactamase
A4R43_01520	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4R43_01525	ENOG4108Z0R	Transferase
A4R43_01530	ENOG4105CHH	sulfate transporter
A4R43_01550	ENOG4105VEQ	Cold shock protein
A4R43_01560	ENOG4108478	ec 3.2.1.18
A4R43_01595	ENOG4105KTU	Transcriptional regulator, arsr family
A4R43_01625	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_01650	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_01665	ENOG4105D2S	major facilitator superfamily
A4R43_01685	ENOG4105MHT	Transcriptional regulator, ARSR family
A4R43_01705	ENOG41082JN	Transcriptional regulator
A4R43_01720	ENOG4105MSB	protein, conserved in bacteria
A4R43_01730	ENOG4105KTU	Transcriptional regulator, arsr family
A4R43_01740	ENOG4105C26	Dehydrogenase
A4R43_01745	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A4R43_01760	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_01790	ENOG4105DRR	Transcriptional regulator, GntR family
A4R43_01795	ENOG4105CMJ	mandelate racemase muconate lactonizing
A4R43_01800	ENOG4105CK2	sodium dicarboxylate symporter
A4R43_01820	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A4R43_01840	ENOG4108KPJ	rna polymerase sigma factor
A4R43_01845	ENOG4108A04	Beta-lactamase
A4R43_01885	ENOG4105YVS	arsR family transcriptional regulator
A4R43_01895	ENOG4107ZYR	domain protein
A4R43_01900	ENOG4105CZN	Potassium uptake protein
A4R43_01915	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A4R43_01955	ENOG4105C0H	protease
A4R43_02030	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A4R43_02050	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4R43_02055	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4R43_02065	ENOG4107QM5	aconitate hydratase
A4R43_02070	ENOG4105DG4	malate L-lactate dehydrogenase
A4R43_02075	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4R43_02110	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A4R43_02115	ENOG4108JQ1	Dehydrogenase
A4R43_02120	ENOG4105JSC	dimethylmenaquinone methyltransferase
A4R43_02125	ENOG4107258	Transcriptional regulator
A4R43_02150	ENOG4108762	serine threonine protein kinase
A4R43_02160	ENOG4108KQ5	Integrase catalytic subunit
A4R43_02165	ENOG4107SQD	Transcriptional regulator, GntR family
A4R43_02185	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
A4R43_02190	ENOG4105WQT	MbtH domain protein
A4R43_02195	ENOG4105BZ1	(ABC) transporter
A4R43_02200	ENOG4105BZ1	(ABC) transporter
A4R43_02310	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A4R43_02390	ENOG4105DEI	Mannitol dehydrogenase
A4R43_02400	ENOG4105CPQ	Dehydrogenase
A4R43_02410	ENOG4105EW9	transcriptional regulator AsnC family
A4R43_02420	ENOG4105CPC	Aldo Keto reductase
A4R43_02425	ENOG4108K2F	hydrolase Family 5
A4R43_02435	ENOG4105C6Z	Gluconate
A4R43_02450	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A4R43_02465	ENOG4105M6F	mutator MutT protein
A4R43_02490	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A4R43_02525	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
A4R43_02540	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_02595	ENOG4105CFG	Acts as a chaperone (By similarity)
A4R43_02615	ENOG4106F60	Histidine kinase
A4R43_02620	ENOG4105F44	Two component transcriptional regulator, winged helix family
A4R43_02625	ENOG4108VBZ	doxx family
A4R43_02645	ENOG4108Q5F	Tetr family transcriptional regulator
A4R43_02650	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
A4R43_02655	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
A4R43_02660	ENOG4105C7W	Xanthine dehydrogenase
A4R43_02665	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A4R43_02675	ENOG4107T8Q	Glycosyl transferase (Group 1
A4R43_02680	ENOG4105C3Q	Glycosyl transferase, family 2
A4R43_02695	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
A4R43_02710	ENOG4105BZG	amino acid carrier protein
A4R43_02715	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A4R43_02740	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_02800	ENOG4105CPQ	Dehydrogenase
A4R43_02805	ENOG4105C57	major facilitator superfamily
A4R43_02815	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A4R43_02885	ENOG4105VPX	protein, conserved in bacteria
A4R43_02935	ENOG4105ENX	hydrolase
A4R43_02965	ENOG4105H3G	oxidoreductase
A4R43_02975	ENOG4107YCR	Transcriptional regulator, ARSR family
A4R43_02980	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_02985	ENOG4105DTQ	mandelate racemase muconate lactonizing
A4R43_02990	ENOG4108QMY	dioxygenase
A4R43_02995	ENOG4105NN7	muconolactone delta-isomerase
A4R43_03005	ENOG4105C57	major facilitator superfamily
A4R43_03025	ENOG4105DJ2	Major Facilitator Superfamily
A4R43_03030	ENOG41080UQ	Transcriptional regulator
A4R43_03040	ENOG4105DU1	integral membrane protein, terc
A4R43_03065	ENOG4105PDP	Short chain dehydrogenase
A4R43_03110	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
A4R43_03115	ENOG4105FUA	antagonist
A4R43_03120	ENOG4107MMM	Anti-sigma-factor antagonist
A4R43_03175	ENOG4108SGK	Tetr family transcriptional regulator
A4R43_03190	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_03265	ENOG4105GFR	rna polymerase sigma factor
A4R43_03280	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4R43_03330	ENOG4108KPJ	rna polymerase sigma factor
A4R43_03345	ENOG4107RSM	transcriptional regulator
A4R43_03350	ENOG4105C7B	Threonine dehydratase
A4R43_03375	ENOG4106YKD	Cytochrome p-450
A4R43_03415	ENOG4108W6C	Dehydrogenase
A4R43_03420	ENOG4108M0I	Transcriptional regulator
A4R43_03425	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_03430	ENOG4105C57	major facilitator superfamily
A4R43_03445	ENOG4107SCK	Monooxygenase
A4R43_03455	ENOG4105C5R	Aminotransferase
A4R43_03460	ENOG4105CQB	FAD linked oxidase domain protein
A4R43_03465	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A4R43_03470	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A4R43_03475	ENOG41060W2	glyoxylate carboligase
A4R43_03535	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_03540	ENOG4108FN7	Aldo keto reductase
A4R43_03550	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A4R43_03555	ENOG4107SCK	Monooxygenase
A4R43_03585	ENOG4105F0K	SARP family transcriptional regulator
A4R43_03590	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
A4R43_03595	ENOG4108KTG	Membrane protein, drug metabolite transporter
A4R43_03605	ENOG4105C5I	Dehydrogenase
A4R43_03610	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4R43_03620	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4R43_03625	ENOG4105C3U	ABC transporter
A4R43_03630	ENOG4108JQ7	(ABC) transporter
A4R43_03640	ENOG4108JQ1	Dehydrogenase
A4R43_03645	ENOG4105EQX	glucarate dehydratase
A4R43_03650	ENOG41069M3	Transcriptional regulator
A4R43_03660	ENOG4108RZE	Tetr family transcriptional regulator
A4R43_03670	ENOG4105CGU	Enoyl-CoA hydratase
A4R43_03690	ENOG4105BZU	Histidine kinase
A4R43_03725	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A4R43_03730	ENOG4105CQB	FAD linked oxidase domain protein
A4R43_03745	ENOG4105C26	Dehydrogenase
A4R43_03755	ENOG4105CPQ	Dehydrogenase
A4R43_03760	ENOG4108TZY	GntR Family Transcriptional Regulator
A4R43_03765	ENOG4105GVF	(ABC) transporter
A4R43_03770	ENOG4105D5T	phosphonate abc transporter
A4R43_03780	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
A4R43_03785	ENOG4105C7W	Xanthine dehydrogenase
A4R43_03790	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
A4R43_03795	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
A4R43_03800	ENOG4108SGK	Tetr family transcriptional regulator
A4R43_03835	ENOG4105DGI	Alkaline phosphatase
A4R43_03855	ENOG4105CHR	reductase
A4R43_03885	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_03895	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4R43_03900	ENOG4107R34	abc transporter permease protein
A4R43_03915	ENOG4105EUJ	GTP cyclohydrolase i
A4R43_03925	ENOG4105E0A	ABC, transporter
A4R43_03930	ENOG4105CC5	ABC transporter
A4R43_03955	ENOG4108PA7	Methyltransferase
A4R43_03975	ENOG4108762	serine threonine protein kinase
A4R43_04015	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
A4R43_04020	ENOG4105CXK	mandelate racemase muconate lactonizing
A4R43_04025	ENOG4108JQ1	Dehydrogenase
A4R43_04035	ENOG4105CNV	Aldolase
A4R43_04040	ENOG4105CPC	Aldo Keto reductase
A4R43_04055	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4R43_04060	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4R43_04065	ENOG4108J59	Extracellular solute-binding protein, family 5
A4R43_04075	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A4R43_04080	ENOG410804X	Transcriptional regulator
A4R43_04085	ENOG4105CHR	reductase
A4R43_04095	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
A4R43_04100	ENOG4105E0A	ABC, transporter
A4R43_04110	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A4R43_04120	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A4R43_04125	ENOG4105CT1	(ABC) transporter
A4R43_04140	ENOG4105KPY	Small multidrug resistance protein
A4R43_04155	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
A4R43_04160	ENOG4105C22	threonyL-tRNA synthetase
A4R43_04185	ENOG4107YQ3	lipid a biosynthesis lauroyl acyltransferase
A4R43_04190	ENOG4105E2K	Glycosyl transferase (Group 1
A4R43_04205	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A4R43_04245	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_04255	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A4R43_04275	ENOG4105KBH	arsR family transcriptional regulator
A4R43_04305	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A4R43_04310	ENOG4105CDY	transcriptional regulatory protein
A4R43_04320	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A4R43_04325	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A4R43_04330	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A4R43_04345	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4R43_04350	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A4R43_04355	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A4R43_04360	ENOG4105E39	Enoyl-CoA hydratase
A4R43_04365	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
A4R43_04390	ENOG4107HP6	Transcriptional regulator
A4R43_04410	ENOG4108JQ6	ABC transporter
A4R43_04430	ENOG4105DTQ	mandelate racemase muconate lactonizing
A4R43_04465	ENOG4105C9M	aspartyl-trna synthetase
A4R43_04495	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A4R43_04505	ENOG4105HSS	phospholipase C
A4R43_04510	ENOG4105C8V	SAICAR synthetase
A4R43_04530	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A4R43_04545	ENOG4105E2X	shikimate dehydrogenase
A4R43_04550	ENOG4105RHY	Pfam:UPF0157
A4R43_04570	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A4R43_04575	ENOG41068W2	Cytochrome p-450
A4R43_04605	ENOG41080Z8	PHOSPHOCARRIER protein
A4R43_04610	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
A4R43_04615	ENOG4105FDP	GntR family transcriptional regulator
A4R43_04620	ENOG4105CI1	PTS System
A4R43_04655	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A4R43_04660	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A4R43_04665	ENOG4105D49	3-dehydroquinate synthase
A4R43_04670	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A4R43_04675	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4R43_04690	ENOG4105DC7	peptidase M24
A4R43_04695	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A4R43_04700	ENOG410803B	Involved in the transcription termination process (By similarity)
A4R43_04715	ENOG4105CXT	aspartate transcarbamylase
A4R43_04730	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A4R43_04735	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A4R43_04740	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
A4R43_04755	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
A4R43_04765	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A4R43_04770	ENOG4107RSZ	Primosomal protein n'
A4R43_04780	ENOG4105C7B	Threonine dehydratase
A4R43_04785	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A4R43_04790	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A4R43_04820	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A4R43_04825	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A4R43_04845	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A4R43_04850	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
A4R43_04855	ENOG4105CHW	UPF0052 protein
A4R43_04860	ENOG4105CIE	May be required for sporulation (By similarity)
A4R43_04905	ENOG410829K	Lysine exporter protein (Lyse ygga)
A4R43_04915	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
A4R43_04920	ENOG4105BZA	Phosphoglycerate kinase
A4R43_04925	ENOG4105CP7	Triose-phosphate isomerase
A4R43_04940	ENOG4105BZU	Histidine kinase
A4R43_04945	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
A4R43_04960	ENOG4107QYV	phosphohexose isomerase
A4R43_04965	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
A4R43_04975	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A4R43_04985	ENOG4105KVH	Transcriptional regulator
A4R43_04990	ENOG4105EEM	helicase
A4R43_04995	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A4R43_05005	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A4R43_05035	ENOG4107JC6	Membrane
A4R43_05055	ENOG4105C3K	feS assembly ATPase SufC
A4R43_05065	ENOG4108UNV	SUF system FeS assembly protein, NifU family
A4R43_05075	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A4R43_05090	ENOG4105BZU	Histidine kinase
A4R43_05095	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_05100	ENOG4105BZU	Histidine kinase
A4R43_05120	ENOG4105C5H	ABC transporter
A4R43_05135	ENOG4105BZ1	(ABC) transporter
A4R43_05150	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A4R43_05155	ENOG4108KGH	TRANSCRIPTIONal
A4R43_05165	ENOG4105BZU	Histidine kinase
A4R43_05175	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A4R43_05180	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4R43_05185	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4R43_05195	ENOG4105E39	Enoyl-CoA hydratase
A4R43_05215	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_05220	ENOG4107QX3	carboxylase
A4R43_05235	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A4R43_05240	ENOG4108IG5	Transcriptional regulator
A4R43_05255	ENOG4105BZU	Histidine kinase
A4R43_05270	ENOG4105CIR	epoxide hydrolase
A4R43_05280	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A4R43_05285	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A4R43_05290	ENOG4105CHR	reductase
A4R43_05295	ENOG4105D8K	carboxyl transferase
A4R43_05305	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A4R43_05310	ENOG4108UKI	Enoyl-CoA hydratase
A4R43_05315	ENOG4108IG5	Transcriptional regulator
A4R43_05325	ENOG4105F9F	transposase
A4R43_05330	ENOG4105D2B	acyl-CoA dehydrogenase
A4R43_05335	ENOG4105D2B	acyl-CoA dehydrogenase
A4R43_05365	ENOG4105JXH	GntR family transcriptional regulator
A4R43_05370	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_05420	ENOG4105DQE	DNA ligase
A4R43_05425	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A4R43_05435	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_05445	ENOG4105BZU	Histidine kinase
A4R43_05475	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4R43_05490	ENOG4105C34	Pseudouridine synthase
A4R43_05505	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_05515	ENOG4105E98	transcriptional regulator DeoR family
A4R43_05520	ENOG4105CGS	Alpha-glucosidase
A4R43_05525	ENOG4105DET	Rhamnulokinase
A4R43_05535	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_05575	ENOG4105F1N	DNA alkylation repair
A4R43_05595	ENOG4105EUB	pirin domain protein
A4R43_05635	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A4R43_05650	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A4R43_05660	ENOG4105CSH	Transporter
A4R43_05670	ENOG4105CJ1	ABC, transporter
A4R43_05680	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_05720	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A4R43_05735	ENOG4105BZU	Histidine kinase
A4R43_05760	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A4R43_05770	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A4R43_05780	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A4R43_05785	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A4R43_05805	ENOG4105CD5	CoA-binding domain protein
A4R43_05830	ENOG4108WYP	Transcriptional regulator
A4R43_05840	ENOG4105C26	Dehydrogenase
A4R43_05855	ENOG4108JB9	formate dehydrogenase
A4R43_05860	ENOG4107QIZ	NADH dehydrogenase
A4R43_05905	ENOG4107HP6	Transcriptional regulator
A4R43_05925	ENOG4105CHF	Glutathione S-transferase
A4R43_05955	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
A4R43_05960	ENOG4105CQB	FAD linked oxidase domain protein
A4R43_05970	ENOG4106A3M	Cytochrome p-450
A4R43_05985	ENOG4105BZW	Glycerate kinase
A4R43_05990	ENOG41060W2	glyoxylate carboligase
A4R43_05995	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A4R43_06000	ENOG4107TFQ	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
A4R43_06010	ENOG4105C7N	Xanthine uracil vitamin C permease
A4R43_06015	ENOG4107Y2X	deaminase
A4R43_06020	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A4R43_06060	ENOG4105CY0	Metallo-Beta-Lactamase
A4R43_06065	ENOG4105EBR	Carboxylesterase
A4R43_06080	ENOG4105C7K	acetolactate synthase
A4R43_06085	ENOG4107RSM	transcriptional regulator
A4R43_06095	ENOG4105E33	succinate dehydrogenase
A4R43_06110	ENOG4105C5Q	Transcriptional regulator
A4R43_06115	ENOG4108J5H	Homocysteine s-methyltransferase
A4R43_06135	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4R43_06155	ENOG4105BZU	Histidine kinase
A4R43_06170	ENOG4105K56	Transcriptional regulator
A4R43_06205	ENOG4105D2S	major facilitator superfamily
A4R43_06215	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A4R43_06230	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
A4R43_06235	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
A4R43_06260	ENOG4107R33	ppx gppa phosphatase
A4R43_06280	ENOG4105C7W	Xanthine dehydrogenase
A4R43_06285	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
A4R43_06290	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
A4R43_06295	ENOG4107RKG	DJ-1/PfpI family
A4R43_06310	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A4R43_06350	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
A4R43_06360	ENOG4108KQ5	Integrase catalytic subunit
A4R43_06375	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_06385	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A4R43_06390	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_06405	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A4R43_06420	ENOG4105CYP	glycoside hydrolase, family
A4R43_06425	ENOG4105CYP	glycoside hydrolase, family
A4R43_06445	ENOG4108IJ9	(ABC) transporter
A4R43_06455	ENOG4105DRS	transport system, permease
A4R43_06470	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_06490	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
A4R43_06505	ENOG4106R7G	Glycoside hydrolase family 5
A4R43_06540	ENOG4108KPJ	rna polymerase sigma factor
A4R43_06550	ENOG410630P	Transcriptional regulator
A4R43_06590	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A4R43_06595	ENOG4105C6Z	Gluconate
A4R43_06610	ENOG4105CSH	Transporter
A4R43_06640	ENOG4107S9B	Shikimate dehydrogenase
A4R43_06685	ENOG4106A3M	Cytochrome p-450
A4R43_06710	ENOG4105BZU	Histidine kinase
A4R43_06720	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A4R43_06755	ENOG4108478	ec 3.2.1.18
A4R43_06765	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4R43_06775	ENOG4105C3U	ABC transporter
A4R43_06785	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4R43_06790	ENOG4105JXH	GntR family transcriptional regulator
A4R43_06810	ENOG4105DND	Transcriptional regulator
A4R43_06830	ENOG4107EFR	Flavocytochrome c
A4R43_06835	ENOG4105DRR	Transcriptional regulator, GntR family
A4R43_06840	ENOG4108K8S	endonuclease I
A4R43_06845	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
A4R43_06905	ENOG4107Y80	Major Facilitator superfamily
A4R43_06915	ENOG4105C37	(CBS) domain
A4R43_06920	ENOG4105C37	(CBS) domain
A4R43_06990	ENOG4105CFC	Transporter
A4R43_07005	ENOG4108W2Y	isochorismatase
A4R43_07020	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_07050	ENOG4108RVA	ribokinase
A4R43_07065	ENOG4105DEN	Luciferase family
A4R43_07075	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A4R43_07095	ENOG4105CTU	Proline racemase
A4R43_07120	ENOG4105CPC	Aldo Keto reductase
A4R43_07135	ENOG4105ENE	Histidine kinase
A4R43_07140	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_07150	ENOG4107RSM	transcriptional regulator
A4R43_07155	ENOG4105F27	Major Facilitator
A4R43_07165	ENOG4105DND	Transcriptional regulator
A4R43_07180	ENOG4105CX8	fg-gap repeat protein
A4R43_07185	ENOG4108222	arsenate reductase
A4R43_07245	ENOG4105CHP	RNA polymerase
A4R43_07250	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A4R43_07285	ENOG4105CJ1	ABC, transporter
A4R43_07340	ENOG4108PSK	reductase
A4R43_07365	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4R43_07395	ENOG4105F8D	glycoside hydrolase family 4
A4R43_07400	ENOG4105E98	transcriptional regulator DeoR family
A4R43_07405	ENOG4107UEK	pfkb domain protein
A4R43_07410	ENOG4107YY3	extracellular solute-binding protein family 1
A4R43_07420	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A4R43_07450	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A4R43_07475	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A4R43_07500	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A4R43_07510	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A4R43_07515	ENOG4105DKP	glycosyl transferase, family 9
A4R43_07520	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A4R43_07525	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A4R43_07530	ENOG4106517	Short-chain dehydrogenase reductase Sdr
A4R43_07540	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A4R43_07550	ENOG4105E1F	short-chain dehydrogenase reductase
A4R43_07560	ENOG4108NBA	ATP-dependent carboxylate-amine ligase (By similarity)
A4R43_07575	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4R43_07580	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4R43_07640	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4R43_07655	ENOG4105ENE	Histidine kinase
A4R43_07660	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_07665	ENOG4105DZC	cytosine deaminase
A4R43_07670	ENOG4105C26	Dehydrogenase
A4R43_07675	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
A4R43_07695	ENOG4105DQ4	alcohol dehydrogenase
A4R43_07760	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_07815	ENOG41082SX	arsR family transcriptional regulator
A4R43_07820	ENOG4107R11	Transcriptional regulator
A4R43_07830	ENOG4105FUY	alpha subunit
A4R43_07905	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_07945	ENOG41061H0	Monooxygenase
A4R43_07950	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_07995	ENOG4108Z6Z	Transcriptional regulator
A4R43_08000	ENOG4105J1Z	Arabinosyltransferase
A4R43_08005	ENOG4105CHH	sulfate transporter
A4R43_08010	ENOG4105CH6	catalase
A4R43_08030	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_08065	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_08080	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A4R43_08085	ENOG4108RZE	Tetr family transcriptional regulator
A4R43_08090	ENOG4105D9U	N-acetyltransferase
A4R43_08100	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A4R43_08110	ENOG4105C57	major facilitator superfamily
A4R43_08120	ENOG4105KVH	Transcriptional regulator
A4R43_08185	ENOG4105CHR	reductase
A4R43_08200	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A4R43_08205	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4R43_08220	ENOG4105CHM	Aminotransferase
A4R43_08230	ENOG4105CIR	epoxide hydrolase
A4R43_08255	ENOG4105CSH	Transporter
A4R43_08295	ENOG4106A3M	Cytochrome p-450
A4R43_08310	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_08340	ENOG4105CHR	reductase
A4R43_08360	ENOG4105CD3	dihydroorotase
A4R43_08370	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A4R43_08390	ENOG4107W53	thymidine kinase
A4R43_08415	ENOG4108ZHR	arsR family transcriptional regulator
A4R43_08445	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4R43_08470	ENOG4105GRZ	Ycii-related protein
A4R43_08475	ENOG4105CHP	RNA polymerase
A4R43_08495	ENOG4107S9F	NmrA family
A4R43_08515	ENOG41079CX	
A4R43_08520	ENOG4105GRZ	Ycii-related protein
A4R43_08525	ENOG4105CHP	RNA polymerase
A4R43_08535	ENOG4105KVH	Transcriptional regulator
A4R43_08550	ENOG41066UM	arsR family transcriptional regulator
A4R43_08560	ENOG4105DA5	(ABC) transporter
A4R43_08565	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_08585	ENOG4105EMU	Dehydrogenase
A4R43_08595	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
A4R43_08630	ENOG4108UV1	cellular component movement
A4R43_08635	ENOG4105RV9	Transcriptional regulator
A4R43_08645	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
A4R43_08675	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4R43_08690	ENOG4105CHP	RNA polymerase
A4R43_08695	ENOG4105GRZ	Ycii-related protein
A4R43_08720	ENOG4107T8P	acyl-Coa dehydrogenase
A4R43_08760	ENOG4105CHP	RNA polymerase
A4R43_08770	ENOG4105F7P	transcriptional regulator AsnC family
A4R43_08780	ENOG4107Y2X	deaminase
A4R43_08795	ENOG4105C0D	helicase
A4R43_08805	ENOG4105CIR	epoxide hydrolase
A4R43_08830	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A4R43_08840	ENOG4105CPC	Aldo Keto reductase
A4R43_08845	ENOG4105CHP	RNA polymerase
A4R43_08855	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4R43_08870	ENOG4108YYH	Nadph-dependent fmn reductase
A4R43_08875	ENOG4105C57	major facilitator superfamily
A4R43_08950	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
A4R43_08970	ENOG41090CE	integral membrane protein
A4R43_08980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4R43_08985	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4R43_08990	ENOG4108J59	Extracellular solute-binding protein, family 5
A4R43_09000	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A4R43_09005	ENOG4105CWX	Alpha-1,2-mannosidase
A4R43_09020	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A4R43_09025	ENOG4105DUX	Transporter
A4R43_09030	ENOG4105DGW	oligopeptidase A
A4R43_09040	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A4R43_09045	ENOG4105DYW	oxidoreductase
A4R43_09050	ENOG4105CPC	Aldo Keto reductase
A4R43_09070	ENOG4105C26	Dehydrogenase
A4R43_09085	ENOG4105EPC	oxidoreductase
A4R43_09090	ENOG4105ESP	cell wall surface anchor family protein
A4R43_09095	ENOG4105E98	transcriptional regulator DeoR family
A4R43_09105	ENOG4108IJ9	(ABC) transporter
A4R43_09110	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A4R43_09115	ENOG4105EG2	ABC transporter, permease
A4R43_09125	ENOG4105E98	transcriptional regulator DeoR family
A4R43_09130	ENOG4105D2N	Aldolase
A4R43_09135	ENOG4105DE4	1-phosphofructokinase
A4R43_09140	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A4R43_09145	ENOG4107YPT	transcriptional regulator
A4R43_09155	ENOG4105DYW	oxidoreductase
A4R43_09160	ENOG4105CHR	reductase
A4R43_09195	ENOG4105GRZ	Ycii-related protein
A4R43_09200	ENOG4105CHP	RNA polymerase
A4R43_09205	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A4R43_09240	ENOG4107QRT	dEAD DEAH box helicase
A4R43_09265	ENOG4108762	serine threonine protein kinase
A4R43_09300	ENOG4105KVH	Transcriptional regulator
A4R43_09315	ENOG4108X7A	Terpene synthase metal-binding domain-containing protein
A4R43_09320	ENOG4105JZI	cytochrome P450
A4R43_09335	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A4R43_09370	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
A4R43_09375	ENOG4108IHU	transport system permease protein
A4R43_09390	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
A4R43_09415	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
A4R43_09430	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A4R43_09450	ENOG4105D2S	major facilitator superfamily
A4R43_09480	ENOG4105ERH	Fumarylacetoacetate hydrolase
A4R43_09495	ENOG4107U9T	Pfam:Ribonuclease_BN
A4R43_09505	ENOG4105CJP	fad dependent oxidoreductase
A4R43_09510	ENOG4105EFZ	amidohydrolase
A4R43_09525	ENOG4108JQ7	(ABC) transporter
A4R43_09530	ENOG4105C3U	ABC transporter
A4R43_09555	ENOG4105C26	Dehydrogenase
A4R43_09565	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A4R43_09570	ENOG4105D17	glycoside hydrolase, family 3 domain protein
A4R43_09590	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
A4R43_09615	ENOG4105EJQ	L-serine dehydratase
A4R43_09650	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A4R43_09655	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A4R43_09665	ENOG4105DVW	rieske (2Fe-2S)
A4R43_09670	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
A4R43_09675	ENOG4105VQD	rieske 2fe-2S domain-containing protein
A4R43_09680	ENOG4107HP6	Transcriptional regulator
A4R43_09685	ENOG4105CSH	Transporter
A4R43_09695	ENOG4108Z6Z	Transcriptional regulator
A4R43_09710	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A4R43_09720	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_09730	ENOG4105EQK	-acetyltransferase
A4R43_09750	ENOG4108IHU	transport system permease protein
A4R43_09760	ENOG4105DT9	hydrolase family 43
A4R43_09770	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A4R43_09815	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_09820	ENOG4105BZU	Histidine kinase
A4R43_09830	ENOG4105D29	Helix-turn-helix type 11 domain protein
A4R43_09835	ENOG4105CIR	epoxide hydrolase
A4R43_09865	ENOG4108Q5F	Tetr family transcriptional regulator
A4R43_09880	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4R43_09890	ENOG4105E0A	ABC, transporter
A4R43_09895	ENOG4105TVJ	transport system, permease
A4R43_09900	ENOG4105DQ5	transport system permease protein
A4R43_09910	ENOG4105Q26	Siderophore-interacting protein
A4R43_09915	ENOG4105WQI	isochorismatase
A4R43_09920	ENOG4105WQI	isochorismatase
A4R43_09925	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
A4R43_09930	ENOG4105E4F	Isochorismate synthase
A4R43_09935	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
A4R43_09940	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
A4R43_09950	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
A4R43_09955	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
A4R43_09960	ENOG4105IW1	AmiS UreI transporter
A4R43_09985	ENOG4105CPC	Aldo Keto reductase
A4R43_09995	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A4R43_10000	ENOG4105HB7	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4R43_10015	ENOG4105CQB	FAD linked oxidase domain protein
A4R43_10030	ENOG4105CSH	Transporter
A4R43_10060	ENOG4105F2W	methyltransferase
A4R43_10065	ENOG4105ECQ	AraC Family Transcriptional Regulator
A4R43_10105	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_10110	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
A4R43_10120	ENOG4105DIA	mandelate racemase muconate lactonizing
A4R43_10130	ENOG4105DU1	integral membrane protein, terc
A4R43_10150	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_10180	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A4R43_10185	ENOG4105C19	ABC transporter
A4R43_10215	ENOG4108KXV	response regulator
A4R43_10230	ENOG4105G63	Type III effector Hrp-dependent
A4R43_10235	ENOG4105FB2	class II Aldolase
A4R43_10240	ENOG4105MVE	transcriptional regulator
A4R43_10315	ENOG4108FUF	Transcriptional regulator, IclR family
A4R43_10320	ENOG4105DG4	malate L-lactate dehydrogenase
A4R43_10325	ENOG4105CSH	Transporter
A4R43_10330	ENOG4105K56	Transcriptional regulator
A4R43_10335	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A4R43_10350	ENOG4107T94	Endo-14-beta-xylanase
A4R43_10355	ENOG4105CXK	mandelate racemase muconate lactonizing
A4R43_10365	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
A4R43_10375	ENOG4108K8U	Glycerol operon regulatory protein
A4R43_10380	ENOG4107WI4	Aldose-1-epimerase
A4R43_10385	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
A4R43_10400	ENOG41062B0	ABC transporter, permease
A4R43_10405	ENOG4107R9N	ABC transporter
A4R43_10410	ENOG4105C2J	ABC transporter
A4R43_10415	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
A4R43_10420	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_10465	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A4R43_10475	ENOG4108RFG	Tetr family transcriptional regulator
A4R43_10480	ENOG4106UW1	Major Facilitator superfamily
A4R43_10510	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A4R43_10515	ENOG4105C5R	Aminotransferase
A4R43_10530	ENOG4105MSB	protein, conserved in bacteria
A4R43_10540	ENOG4105BZU	Histidine kinase
A4R43_10550	ENOG4105EXC	Acyl-transferase
A4R43_10565	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4R43_10575	ENOG4107TXC	Transcriptional regulator
A4R43_10625	ENOG4105CD3	dihydroorotase
A4R43_10635	ENOG41079KZ	Major Facilitator Superfamily
A4R43_10645	ENOG410829K	Lysine exporter protein (Lyse ygga)
A4R43_10675	ENOG4105J0Q	Transcriptional regulator
A4R43_10710	ENOG4105CQR	helicase
A4R43_10730	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A4R43_10740	ENOG4107TMB	Transcriptional regulator
A4R43_10750	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
A4R43_10760	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
A4R43_10770	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A4R43_10775	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A4R43_10780	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
A4R43_10785	ENOG4105E5F	proteasome
A4R43_10790	ENOG4105PTV	Nudix Hydrolase
A4R43_10805	ENOG4107SMB	hydrolase Family 5
A4R43_10815	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
A4R43_10855	ENOG4105RK9	auxin efflux carrier
A4R43_10860	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A4R43_10865	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
A4R43_10875	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A4R43_10880	ENOG4105C3R	Methionine synthase
A4R43_10895	ENOG4105C57	major facilitator superfamily
A4R43_10900	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_10925	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_10960	ENOG4105C8N	cysteinyl-tRNA synthetase
A4R43_10965	ENOG4107TXC	Transcriptional regulator
A4R43_10995	ENOG4107KWJ	von Willebrand factor, type A
A4R43_11005	ENOG4108UF8	
A4R43_11010	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A4R43_11015	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A4R43_11020	ENOG4108IND	Tetr family transcriptional regulator
A4R43_11040	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A4R43_11050	ENOG4108KXV	response regulator
A4R43_11065	ENOG4105FQP	Beta-lactamase
A4R43_11075	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A4R43_11080	ENOG4107QVM	von Willebrand factor, type A
A4R43_11090	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4R43_11095	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A4R43_11105	ENOG4105ZXU	NLP P60 protein
A4R43_11120	ENOG4107QM5	aconitate hydratase
A4R43_11135	ENOG41067HS	methyltransferase
A4R43_11140	ENOG4108V75	Glutamine amidotransferase
A4R43_11145	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
A4R43_11155	ENOG4105C5Q	Transcriptional regulator
A4R43_11160	ENOG4105D82	Glutamate dehydrogenase
A4R43_11185	ENOG4108Q5F	Tetr family transcriptional regulator
A4R43_11255	ENOG4108UW8	fha domain-containing protein
A4R43_11260	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A4R43_11280	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A4R43_11295	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A4R43_11310	ENOG4108BT0	50S ribosomal protein L32
A4R43_11315	ENOG4105NRA	50s ribosomal protein l31 type b
A4R43_11325	ENOG4105KDC	50s ribosomal protein l28
A4R43_11330	ENOG4105W0E	50S ribosomal protein L33
A4R43_11335	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A4R43_11340	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A4R43_11350	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A4R43_11370	ENOG4107R72	Ceramidase
A4R43_11375	ENOG4105DYW	oxidoreductase
A4R43_11415	ENOG4105YIP	Tetr family transcriptional regulator
A4R43_11420	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A4R43_11425	ENOG4105CJ2	(LipO)protein
A4R43_11440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4R43_11445	ENOG4105BZU	Histidine kinase
A4R43_11455	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A4R43_11465	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4R43_11475	ENOG4105F8D	glycoside hydrolase family 4
A4R43_11480	ENOG4105DRS	transport system, permease
A4R43_11485	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
A4R43_11505	ENOG4105C5H	ABC transporter
A4R43_11510	ENOG41066UM	arsR family transcriptional regulator
A4R43_11530	ENOG4105BZU	Histidine kinase
A4R43_11555	ENOG4105ESN	nucleotide-binding protein
A4R43_11560	ENOG4105ESN	nucleotide-binding protein
A4R43_11595	ENOG4105K6H	D-cysteine desulfhydrase
A4R43_11620	ENOG4105FDF	Could be involved in DNA repair (By similarity)
A4R43_11630	ENOG4105CIG	ABC transporter
A4R43_11640	ENOG4105BZU	Histidine kinase
A4R43_11645	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_11650	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A4R43_11655	ENOG4108VJY	integral membrane protein
A4R43_11670	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A4R43_11690	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A4R43_11695	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A4R43_11705	ENOG4108UGD	Serine Threonine protein kinase
A4R43_11720	ENOG4106T9R	serine protease
A4R43_11725	ENOG4108KPJ	rna polymerase sigma factor
A4R43_11730	ENOG4105CSH	Transporter
A4R43_11735	ENOG4108KXM	LysR family Transcriptional regulator
A4R43_11740	ENOG4106T9R	serine protease
A4R43_11745	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4R43_11825	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_11840	ENOG4105DDN	Pentapeptide repeat-containing protein
A4R43_11890	ENOG4105C0Z	ABC transporter
A4R43_11895	ENOG4108IV0	ABC, transporter
A4R43_11915	ENOG4105U5Y	Transcriptional regulator
A4R43_11930	ENOG4108XXK	NUDIX hydrolase
A4R43_11980	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_11985	ENOG4105E2R	ROK family
A4R43_11990	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A4R43_11995	ENOG4105D56	permease protein
A4R43_12005	ENOG4107XHQ	chlorophyll synthesis pathway, bchC
A4R43_12010	ENOG4107TYA	transient receptor potential locus
A4R43_12030	ENOG4105E5G	Alpha beta hydrolase fold
A4R43_12040	ENOG4105F27	Major Facilitator
A4R43_12045	ENOG4105F04	LysR family Transcriptional regulator
A4R43_12050	ENOG4105D4T	Citrate transporter
A4R43_12070	ENOG4105EPJ	extracellular solute-binding protein family 1
A4R43_12085	ENOG4107Q25	Serine Threonine protein kinase
A4R43_12120	ENOG4105EX0	alpha-galactosidase
A4R43_12140	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_12145	ENOG4105F0K	SARP family transcriptional regulator
A4R43_12265	ENOG4105EC2	ftsk spoIIIe
A4R43_12285	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_12300	ENOG4107TPY	serine threonine protein kinase
A4R43_12385	ENOG4107RTG	Major Facilitator superfamily
A4R43_12460	ENOG4105VEQ	Cold shock protein
A4R43_12470	ENOG4105FDR	Membrane
A4R43_12485	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_12500	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4R43_12520	ENOG4105IIU	Aminopeptidase
A4R43_12545	ENOG4108IG5	Transcriptional regulator
A4R43_12595	ENOG4106A3M	Cytochrome p-450
A4R43_12600	ENOG4105CJA	serine threonine protein kinase
A4R43_12615	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A4R43_12620	ENOG4105CHR	reductase
A4R43_12625	ENOG4107EEY	synthase
A4R43_12645	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A4R43_12655	ENOG4105C7K	acetolactate synthase
A4R43_12695	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4R43_12705	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_12715	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4R43_12725	ENOG4105DKW	ABC transporter
A4R43_12730	ENOG4107S4Y	M20 DapE family protein YgeY
A4R43_12740	ENOG4105CSH	Transporter
A4R43_12750	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
A4R43_12770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A4R43_12775	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A4R43_12825	ENOG4108KPJ	rna polymerase sigma factor
A4R43_12905	ENOG4105E0A	ABC, transporter
A4R43_12915	ENOG4105DQ5	transport system permease protein
A4R43_12940	ENOG4105C57	major facilitator superfamily
A4R43_12970	ENOG4105C2J	ABC transporter
A4R43_13020	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_13025	ENOG4105H3G	oxidoreductase
A4R43_13080	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
A4R43_13100	ENOG4107SCK	Monooxygenase
A4R43_13110	ENOG4105CSH	Transporter
A4R43_13115	ENOG4105GVJ	transcriptional regulator
A4R43_13125	ENOG4105W1N	transcriptional regulator
A4R43_13140	ENOG4108Z40	Transcriptional regulator
A4R43_13145	ENOG4105D9P	serine threonine protein kinase
A4R43_13160	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A4R43_13230	ENOG4105BZW	Glycerate kinase
A4R43_13240	ENOG4107RN3	metallophosphoesterase
A4R43_13245	ENOG4105CPQ	Dehydrogenase
A4R43_13250	ENOG4105C01	Dihydroxy-acid dehydratase
A4R43_13285	ENOG4105I4A	GCN5-related N-acetyltransferase
A4R43_13315	ENOG4107UBR	Extracellular solute-binding protein family 3
A4R43_13325	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_13335	ENOG4105KVH	Transcriptional regulator
A4R43_13340	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A4R43_13365	ENOG4105CHR	reductase
A4R43_13370	ENOG4105CSH	Transporter
A4R43_13410	ENOG4105C0Z	ABC transporter
A4R43_13415	ENOG4108IV0	ABC, transporter
A4R43_13425	ENOG4105CHR	reductase
A4R43_13440	ENOG4105CI2	imidazolone-5-propionate hydrolase
A4R43_13460	ENOG4108JQ6	ABC transporter
A4R43_13465	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4R43_13495	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4R43_13505	ENOG4105CPQ	Dehydrogenase
A4R43_13510	ENOG4105CPC	Aldo Keto reductase
A4R43_13525	ENOG4105C26	Dehydrogenase
A4R43_13530	ENOG4105ERH	Fumarylacetoacetate hydrolase
A4R43_13535	ENOG4105DRR	Transcriptional regulator, GntR family
A4R43_13540	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4R43_13585	ENOG4105CIR	epoxide hydrolase
A4R43_13595	ENOG4108VJY	integral membrane protein
A4R43_13600	ENOG4105CFQ	glutamine synthetase
A4R43_13620	ENOG41083YR	Protein CrcB homolog
A4R43_13625	ENOG41083TI	Protein CrcB homolog
A4R43_13640	ENOG4105CSR	polyphosphate kinase 2
A4R43_13645	ENOG4105C8Y	Acetylornithine aminotransferase
A4R43_13680	ENOG4105EMN	RNA polymerase sigma factor
A4R43_13690	ENOG4105VBF	alkaline shock protein
A4R43_13715	ENOG4105BZU	Histidine kinase
A4R43_13745	ENOG4105DQE	DNA ligase
A4R43_13755	ENOG4108N5C	SNARE associated Golgi protein-related protein
A4R43_13770	ENOG4105C5F	glutamine synthetase
A4R43_13780	ENOG4105E0X	reductase
A4R43_13800	ENOG4105E18	UPF0276 protein
A4R43_13810	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
A4R43_13820	ENOG4107JTW	chlorite dismutase
A4R43_13825	ENOG4105C1Q	protoporphyrinogen oxidase
A4R43_13830	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A4R43_13840	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A4R43_13845	ENOG4105P3N	Membrane
A4R43_13865	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_13890	ENOG4105CHU	acetyl-coa acetyltransferase
A4R43_13895	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4R43_13915	ENOG4106F60	Histidine kinase
A4R43_13920	ENOG4105F44	Two component transcriptional regulator, winged helix family
A4R43_13945	ENOG4105C26	Dehydrogenase
A4R43_13975	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A4R43_13985	ENOG4105EXC	Acyl-transferase
A4R43_13990	ENOG4105C26	Dehydrogenase
A4R43_14005	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A4R43_14010	ENOG4105C0X	amino acid
A4R43_14015	ENOG4107VEG	TrkA-N domain protein
A4R43_14055	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
A4R43_14095	ENOG4105KVH	Transcriptional regulator
A4R43_14105	ENOG4105DKQ	ROK family
A4R43_14110	ENOG4105YIP	Tetr family transcriptional regulator
A4R43_14115	ENOG4106A3M	Cytochrome p-450
A4R43_14135	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A4R43_14155	ENOG4107S91	Sodium hydrogen exchanger
A4R43_14165	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A4R43_14170	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A4R43_14205	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A4R43_14210	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A4R43_14230	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A4R43_14245	ENOG4105DSU	hydrolase
A4R43_14270	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A4R43_14275	ENOG4108VX5	3-methyladenine DNA glycosylase
A4R43_14300	ENOG4105CH7	arginosuccinase
A4R43_14305	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
A4R43_14310	ENOG4105DBV	ornithine carbamoyltransferase
A4R43_14315	ENOG4105C8Y	Acetylornithine aminotransferase
A4R43_14320	ENOG4105CAS	nag kinase
A4R43_14325	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
A4R43_14330	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A4R43_14345	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A4R43_14350	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A4R43_14355	ENOG4108RWN	rrna methyltransferase
A4R43_14360	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A4R43_14365	ENOG41084BS	50S ribosomal protein L35
A4R43_14385	ENOG4105K6H	D-cysteine desulfhydrase
A4R43_14415	ENOG4105C6Z	Gluconate
A4R43_14420	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
A4R43_14425	ENOG4108KQ5	Integrase catalytic subunit
A4R43_14445	ENOG4105E2D	ec 3.2.1.52
A4R43_14450	ENOG4107TB5	TRANSCRIPTIONal
A4R43_14460	ENOG4108MRH	transcriptional regulatory protein
A4R43_14465	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A4R43_14470	ENOG4107QJT	sodium dicarboxylate symporter
A4R43_14490	ENOG4105C5X	domain protein
A4R43_14520	ENOG4105DQE	DNA ligase
A4R43_14540	ENOG4105MHT	Transcriptional regulator, ARSR family
A4R43_14550	ENOG4105CDA	abc transporter atp-binding protein
A4R43_14555	ENOG4108HW4	amino acid AbC transporter
A4R43_14560	ENOG4105E89	ABC transporter
A4R43_14570	ENOG4108TGR	phosphatase
A4R43_14575	ENOG4105C4B	ABC transporter, permease
A4R43_14585	ENOG4105CGD	Nad-dependent epimerase dehydratase
A4R43_14590	ENOG4105C7B	Threonine dehydratase
A4R43_14610	ENOG4108FN7	Aldo keto reductase
A4R43_14615	ENOG4105CMG	Carbohydrate kinase
A4R43_14625	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_14630	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
A4R43_14635	ENOG4105CNN	ABC, transporter
A4R43_14640	ENOG4105C2J	ABC transporter
A4R43_14660	ENOG4106F59	XRE family Transcriptional regulator
A4R43_14670	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A4R43_14680	ENOG4105CJ1	ABC, transporter
A4R43_14710	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A4R43_14715	ENOG4105CJ1	ABC, transporter
A4R43_14730	ENOG4105BZU	Histidine kinase
A4R43_14735	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_14740	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A4R43_14760	ENOG4107EEY	synthase
A4R43_14765	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A4R43_14790	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A4R43_14795	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A4R43_14815	ENOG4105ECB	domain protein
A4R43_14850	ENOG4106AXJ	AraC family transcriptional regulator
A4R43_14865	ENOG4105JQN	Transcriptional regulator
A4R43_14875	ENOG4108IV0	ABC, transporter
A4R43_14880	ENOG4105C0Z	ABC transporter
A4R43_14885	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A4R43_14890	ENOG4105C32	Amino acid ABC transporter (Permease)
A4R43_14895	ENOG4105CP9	extracellular ligand-binding receptor
A4R43_15000	ENOG4105K4H	Nlp p60 protein
A4R43_15025	ENOG4105BZU	Histidine kinase
A4R43_15045	ENOG4105P8F	nudix hydrolase
A4R43_15075	ENOG4105CNA	YD repeat protein
A4R43_15135	ENOG4105KF0	sporulation and cell division protein, SsgA
A4R43_15155	ENOG4105BZU	Histidine kinase
A4R43_15160	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_15175	ENOG4108KTG	Membrane protein, drug metabolite transporter
A4R43_15190	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A4R43_15200	ENOG4105BZU	Histidine kinase
A4R43_15215	ENOG4105VBF	alkaline shock protein
A4R43_15275	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_15280	ENOG4105F0K	SARP family transcriptional regulator
A4R43_15285	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
A4R43_15305	ENOG4105CPQ	Dehydrogenase
A4R43_15330	ENOG4108XFH	Transcriptional regulator
A4R43_15375	ENOG4105EYF	MMPL domain protein
A4R43_15380	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_15390	ENOG4105CJ1	ABC, transporter
A4R43_15425	ENOG4107S9F	NmrA family
A4R43_15450	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A4R43_15465	ENOG4105DQE	DNA ligase
A4R43_15475	ENOG4105PF9	Transcriptional regulator
A4R43_15510	ENOG4105DEG	Vwa containing coxe family protein
A4R43_15520	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
A4R43_15540	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A4R43_15580	ENOG4107QRI	Phosphoketolase
A4R43_15585	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A4R43_15635	ENOG4105MC2	DSBA oxidoreductase
A4R43_15645	ENOG4105EX0	alpha-galactosidase
A4R43_15665	ENOG4106AM8	polysaccharide lyase family 8
A4R43_15680	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
A4R43_15685	ENOG4107HP6	Transcriptional regulator
A4R43_15690	ENOG4105E9Z	Nad-dependent epimerase dehydratase
A4R43_15695	ENOG4107RN6	Monooxygenase
A4R43_15730	ENOG4105IIP	Membrane
A4R43_15740	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_15760	ENOG4108HWW	ABC transporter
A4R43_15765	ENOG4105C2J	ABC transporter
A4R43_15770	ENOG4105DFW	ABC transporter
A4R43_15810	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
A4R43_15815	ENOG4105D7K	pfkb domain protein
A4R43_15825	ENOG4105CH2	amidohydrolase
A4R43_15835	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4R43_15840	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A4R43_15850	ENOG4107GFK	fumarate
A4R43_15865	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A4R43_15870	ENOG4105FDP	GntR family transcriptional regulator
A4R43_15890	ENOG4106YT9	Enoyl-CoA hydratase
A4R43_15895	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
A4R43_15920	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_15925	ENOG4106A3M	Cytochrome p-450
A4R43_15930	ENOG4105F2C	Acetyl-CoA acetyltransferase
A4R43_15940	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
A4R43_15950	ENOG4105E39	Enoyl-CoA hydratase
A4R43_15965	ENOG4105EA8	2-Nitropropane dioxygenase
A4R43_15970	ENOG4108VQT	Alpha beta hydrolase fold protein
A4R43_15975	ENOG4108UW5	maltose o-acetyltransferase
A4R43_15980	ENOG4105F2C	Acetyl-CoA acetyltransferase
A4R43_15985	ENOG4108RZE	Tetr family transcriptional regulator
A4R43_15990	ENOG4105CHR	reductase
A4R43_15995	ENOG4105CC9	acyl-Coa dehydrogenase
A4R43_16000	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_16010	ENOG4105CC9	acyl-Coa dehydrogenase
A4R43_16015	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_16030	ENOG4105MXW	flavin reductase domain protein, FMN-binding
A4R43_16035	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4R43_16040	ENOG41088PD	hydrolase
A4R43_16045	ENOG4108KC1	acyl-Coa dehydrogenase
A4R43_16055	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
A4R43_16070	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A4R43_16095	ENOG4105X7H	acyl-CoA dehydrogenase
A4R43_16100	ENOG4108RK3	acyl-Coa dehydrogenase
A4R43_16105	ENOG4105ECQ	AraC Family Transcriptional Regulator
A4R43_16110	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
A4R43_16120	ENOG4105C0D	helicase
A4R43_16125	ENOG4105D2B	acyl-CoA dehydrogenase
A4R43_16130	ENOG4108SGK	Tetr family transcriptional regulator
A4R43_16140	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
A4R43_16160	ENOG4105D5P	Methylmalonyl-coA mutase
A4R43_16175	ENOG4105GWZ	Roadblock lc7 family protein
A4R43_16190	ENOG4107QN1	sodium solute
A4R43_16200	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A4R43_16225	ENOG4105XM7	Lipoprotein lprD
A4R43_16240	ENOG410846T	CoA-transferase family III
A4R43_16245	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_16260	ENOG4105C26	Dehydrogenase
A4R43_16270	ENOG4107SM8	Adenylate Guanylate cyclase
A4R43_16290	ENOG4105C29	acyl-CoA thioesterase
A4R43_16325	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A4R43_16335	ENOG4105E9Q	Acyl-transferase
A4R43_16350	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
A4R43_16360	ENOG4105DKQ	ROK family
A4R43_16370	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
A4R43_16455	ENOG4105C9B	Cysteine desulfurase
A4R43_16465	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
A4R43_16470	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A4R43_16495	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
A4R43_16520	ENOG4105K6V	RNA polymerase
A4R43_16535	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A4R43_16555	ENOG4105ME9	cell division protein FtsQ
A4R43_16560	ENOG4105DFU	Cell wall formation (By similarity)
A4R43_16575	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A4R43_16580	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A4R43_16650	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
A4R43_16655	ENOG4105X7H	acyl-CoA dehydrogenase
A4R43_16660	ENOG4108KC2	acyl-Coa dehydrogenase
A4R43_16675	ENOG4105DGU	Histone deacetylase
A4R43_16680	ENOG4105KHC	sulfurtransferase
A4R43_16690	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A4R43_16695	ENOG4105CMR	udp-glucose 4-epimerase
A4R43_16710	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
A4R43_16735	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
A4R43_16745	ENOG4105CGZ	zinc metallopeptidase
A4R43_16760	ENOG4107XEY	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A4R43_16775	ENOG4105C0D	helicase
A4R43_16780	ENOG4107XWB	Zinc finger, swim domain protein
A4R43_16805	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4R43_16810	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A4R43_16820	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A4R43_16830	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A4R43_16845	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A4R43_16850	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A4R43_16860	ENOG4105C99	atpase involved in dna repair
A4R43_16875	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A4R43_16880	ENOG410839S	Toxic component of a toxin-antitoxin (TA) module (By similarity)
A4R43_16895	ENOG41065SU	Two-component system sensor kinase
A4R43_16900	ENOG4108PYU	two-component system response regulator
A4R43_16905	ENOG4105CDA	abc transporter atp-binding protein
A4R43_16910	ENOG4107UBR	Extracellular solute-binding protein family 3
A4R43_16915	ENOG4108Q1T	ABC transporter
A4R43_16920	ENOG4105DRP	amino acid AbC transporter
A4R43_16930	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
A4R43_16945	ENOG4105C01	Dihydroxy-acid dehydratase
A4R43_16950	ENOG4108UHU	Aldolase
A4R43_16960	ENOG4105KC9	Modulates RecA activity (By similarity)
A4R43_16965	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A4R43_16975	ENOG4108KBA	Acts as a chaperone (By similarity)
A4R43_16980	ENOG4107QRT	dEAD DEAH box helicase
A4R43_16985	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A4R43_17025	ENOG4105C7B	Threonine dehydratase
A4R43_17030	ENOG4105DND	Transcriptional regulator
A4R43_17075	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
A4R43_17100	ENOG4105DZ6	Band 7 protein
A4R43_17120	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
A4R43_17135	ENOG4105DND	Transcriptional regulator
A4R43_17155	ENOG4105CBC	glutamate synthase
A4R43_17160	ENOG4107V6M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A4R43_17195	ENOG4105C6T	cysteine synthase
A4R43_17205	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
A4R43_17225	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A4R43_17230	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A4R43_17235	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A4R43_17245	ENOG4105CRQ	synthase (Component I)
A4R43_17250	ENOG4108X07	Tetr family transcriptional regulator
A4R43_17255	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A4R43_17265	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A4R43_17300	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
A4R43_17305	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A4R43_17320	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A4R43_17325	ENOG4105R40	Glycine betaine carnitine choline
A4R43_17330	ENOG4105D2X	ABC transporter substrate-binding protein
A4R43_17340	ENOG4105GWZ	Roadblock lc7 family protein
A4R43_17350	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_17365	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
A4R43_17375	ENOG4105C1J	atp-dependent rna helicase
A4R43_17390	ENOG4105PNM	synthesis protein
A4R43_17420	ENOG4108Z4X	TRANSCRIPTIONal
A4R43_17435	ENOG41082AN	stage II sporulation protein
A4R43_17440	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
A4R43_17445	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A4R43_17450	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A4R43_17460	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A4R43_17470	ENOG4108S01	response regulator
A4R43_17490	ENOG4107Q1J	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A4R43_17505	ENOG4105EC2	ftsk spoIIIe
A4R43_17550	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A4R43_17555	ENOG4108IYU	L-aspartate oxidase
A4R43_17560	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A4R43_17575	ENOG4105D0M	Protease HtpX homolog
A4R43_17590	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A4R43_17595	ENOG4107WHG	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A4R43_17600	ENOG4105CHH	sulfate transporter
A4R43_17605	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A4R43_17610	ENOG4106A3M	Cytochrome p-450
A4R43_17630	ENOG4108KPJ	rna polymerase sigma factor
A4R43_17635	ENOG4105JNK	Glycosyl transferase (Group 1
A4R43_17650	ENOG4108UZE	carboxy-peptidase
A4R43_17660	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A4R43_17685	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A4R43_17695	ENOG4107UDY	cytochrome C
A4R43_17700	ENOG4105CCU	oxidase (Subunit III)
A4R43_17710	ENOG4107S1N	anthranilate phosphoribosyltransferase
A4R43_17715	ENOG4108ZRS	Part of cytochrome c oxidase, its function is
A4R43_17720	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
A4R43_17735	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
A4R43_17745	ENOG4107HP6	Transcriptional regulator
A4R43_17770	ENOG4105CPC	Aldo Keto reductase
A4R43_17775	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A4R43_17785	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A4R43_17805	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A4R43_17830	ENOG4105YIP	Tetr family transcriptional regulator
A4R43_17860	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A4R43_17885	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A4R43_17890	ENOG4105DQR	SNARE associated Golgi
A4R43_17930	ENOG4105C0B	DNA polymerase III (alpha subunit)
A4R43_17935	ENOG4105FDP	GntR family transcriptional regulator
A4R43_17970	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
A4R43_17985	ENOG4105D74	hydrolase
A4R43_18030	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A4R43_18040	ENOG4105DAA	L-lactate
A4R43_18070	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A4R43_18075	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4R43_18080	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A4R43_18115	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A4R43_18120	ENOG4105W8H	transhydrogenase (subunit alpha
A4R43_18125	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A4R43_18130	ENOG4105EJ2	Transcriptional regulator
A4R43_18155	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_18160	ENOG4107ZED	Uncharacterised protein family UPF0047
A4R43_18180	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A4R43_18200	ENOG4107XFJ	UPF0246 protein
A4R43_18205	ENOG4107VFR	oxidoreductase
A4R43_18225	ENOG4105C1J	atp-dependent rna helicase
A4R43_18235	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A4R43_18245	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
A4R43_18260	ENOG4105DJ2	Major Facilitator Superfamily
A4R43_18265	ENOG4105JXH	GntR family transcriptional regulator
A4R43_18270	ENOG4105KVH	Transcriptional regulator
A4R43_18310	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A4R43_18325	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A4R43_18330	ENOG4105DZP	Membrane-associated zinc metalloprotease
A4R43_18335	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
A4R43_18355	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A4R43_18360	ENOG4105NTW	Transcriptional regulator
A4R43_18380	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A4R43_18385	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A4R43_18390	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A4R43_18395	ENOG4105CE9	30S ribosomal protein S2
A4R43_18405	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4R43_18410	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4R43_18420	ENOG4105C0P	Mg chelatase subunit ChlI
A4R43_18425	ENOG41080R2	UPF0102 protein
A4R43_18435	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A4R43_18440	ENOG4107QYR	Signal peptidase i
A4R43_18445	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A4R43_18450	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A4R43_18455	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A4R43_18465	ENOG4105K5M	30s ribosomal protein S16
A4R43_18490	ENOG4105FDF	Could be involved in DNA repair (By similarity)
A4R43_18500	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A4R43_18530	ENOG4107S5I	aldo keto reductase
A4R43_18540	ENOG4105K4P	CoA-binding domain protein
A4R43_18580	ENOG4105C2W	permease
A4R43_18585	ENOG4105J7D	transcriptional regulator
A4R43_18600	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A4R43_18605	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A4R43_18630	ENOG4107R9S	Malate synthase
A4R43_18635	ENOG41069M3	Transcriptional regulator
A4R43_18640	ENOG4108MK9	spermidine N(1)-acetyltransferase
A4R43_18650	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
A4R43_18655	ENOG4107RJ1	sodium solute
A4R43_18675	ENOG4108375	Acylphosphatase (EC 3.6.1.7)
A4R43_18695	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
A4R43_18700	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A4R43_18705	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A4R43_18715	ENOG4105CAQ	asparagine synthetase
A4R43_18755	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A4R43_18760	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A4R43_18765	ENOG41084BZ	50S ribosomal protein L32
A4R43_18785	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
A4R43_18790	ENOG4106H78	methyltransferase
A4R43_18795	ENOG4105EEM	helicase
A4R43_18800	ENOG4105DEN	Luciferase family
A4R43_18895	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A4R43_18900	ENOG4107QN1	sodium solute
A4R43_18910	ENOG4107QN1	sodium solute
A4R43_18920	ENOG4105DY9	regulatoR
A4R43_18925	ENOG4108HRK	Histidine kinase
A4R43_18935	ENOG4105CD3	dihydroorotase
A4R43_18980	ENOG4105D7T	ABC transporter
A4R43_18990	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
A4R43_18995	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_19015	ENOG4105F9F	transposase
A4R43_19035	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_19045	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_19050	ENOG4105C2M	dna polymerase I
A4R43_19060	ENOG4105CQ7	ATP-dependent helicase
A4R43_19070	ENOG4105DMF	Dehydrogenase
A4R43_19075	ENOG4107S91	Sodium hydrogen exchanger
A4R43_19085	ENOG4105C2C	drug resistance transporter, Bcr CflA
A4R43_19090	ENOG4108RYK	Nad-dependent epimerase dehydratase
A4R43_19110	ENOG4105PDP	Short chain dehydrogenase
A4R43_19115	ENOG4105E0A	ABC, transporter
A4R43_19125	ENOG4105BZ4	penicillin-binding protein
A4R43_19130	ENOG41073TP	transcriptional regulator
A4R43_19135	ENOG4105EJQ	L-serine dehydratase
A4R43_19140	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A4R43_19145	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A4R43_19150	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A4R43_19155	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A4R43_19160	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A4R43_19170	ENOG4105C26	Dehydrogenase
A4R43_19175	ENOG4108Z86	Glutamine amidotransferase
A4R43_19185	ENOG4105CUB	amino acid
A4R43_19190	ENOG4105F9F	transposase
A4R43_19205	ENOG4105CK5	oxidoreductase
A4R43_19210	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_19215	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
A4R43_19220	ENOG4105D4B	ABC, transporter
A4R43_19225	ENOG41062B0	ABC transporter, permease
A4R43_19230	ENOG4105C2J	ABC transporter
A4R43_19235	ENOG4105EDK	PfkB domain protein
A4R43_19245	ENOG4105DH8	myo-inositol catabolism
A4R43_19250	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
A4R43_19260	ENOG4105GRZ	Ycii-related protein
A4R43_19265	ENOG4105H3G	oxidoreductase
A4R43_19300	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
A4R43_19310	ENOG4105F9F	transposase
A4R43_19315	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A4R43_19320	ENOG4105CPQ	Dehydrogenase
A4R43_19325	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
A4R43_19330	ENOG4105CTS	PTS system mannitol-specific
A4R43_19340	ENOG4105DE4	1-phosphofructokinase
A4R43_19345	ENOG4105E98	transcriptional regulator DeoR family
A4R43_19355	ENOG4107HP6	Transcriptional regulator
A4R43_19360	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
A4R43_19365	ENOG4105F2Z	3-oxoadipate enol-lactonase
A4R43_19380	ENOG4105CHU	acetyl-coa acetyltransferase
A4R43_19405	ENOG4105BZW	Glycerate kinase
A4R43_19445	ENOG4107R7A	Allophanate hydrolase subunit 2
A4R43_19450	ENOG4105P4J	Allophanate hydrolase, subunit 1
A4R43_19455	ENOG4105CFM	UPF0317 protein
A4R43_19460	ENOG4107RGD	Major Facilitator superfamily
A4R43_19495	ENOG4105DP4	dak2 domain fusion protein ylov
A4R43_19500	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
A4R43_19505	ENOG4108Z0R	Transferase
A4R43_19535	ENOG4105CPF	Cell wall formation (By similarity)
A4R43_19540	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_19555	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4R43_19565	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
A4R43_19590	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4R43_19595	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4R43_19605	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
A4R43_19630	ENOG4105BZU	Histidine kinase
A4R43_19655	ENOG4105CHM	Aminotransferase
A4R43_19660	ENOG4105EYF	MMPL domain protein
A4R43_19705	ENOG4105CIG	ABC transporter
A4R43_19715	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
A4R43_19740	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
A4R43_19745	ENOG4105KVH	Transcriptional regulator
A4R43_19750	ENOG4107STQ	Multicopper oxidase
A4R43_19760	ENOG4105DND	Transcriptional regulator
A4R43_19770	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A4R43_19775	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4R43_19820	ENOG4107Z3H	Transcriptional regulator, TetR family
A4R43_19840	ENOG4107S1E	Beta-lactamase
A4R43_19845	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_19850	ENOG4105VPX	protein, conserved in bacteria
A4R43_19855	ENOG4108IG5	Transcriptional regulator
A4R43_19860	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
A4R43_19870	ENOG4105KME	endoribonuclease L-psp
A4R43_19880	ENOG4105YVS	arsR family transcriptional regulator
A4R43_19925	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A4R43_19930	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A4R43_19940	ENOG4105ERH	Fumarylacetoacetate hydrolase
A4R43_19945	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A4R43_19950	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4R43_19955	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_19990	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A4R43_19995	ENOG4108ZP8	Acetolactate synthase small subunit
A4R43_20010	ENOG4105C01	Dihydroxy-acid dehydratase
A4R43_20040	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A4R43_20050	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4R43_20055	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A4R43_20070	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A4R43_20085	ENOG4105C4K	Nad synthetase
A4R43_20095	ENOG4105C5X	domain protein
A4R43_20115	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A4R43_20125	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4R43_20140	ENOG4105C10	Electron transfer flavoprotein
A4R43_20150	ENOG4105EPR	degv family
A4R43_20160	ENOG4108KQJ	Type 11 methyltransferase
A4R43_20170	ENOG4108V06	Glutathione peroxidase
A4R43_20215	ENOG4107R9S	Malate synthase
A4R43_20240	ENOG4105EVB	acetyltransferase
A4R43_20280	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4R43_20290	ENOG4105NPE	arsR family transcriptional regulator
A4R43_20305	ENOG4105F27	Major Facilitator
A4R43_20310	ENOG4108Z6Z	Transcriptional regulator
A4R43_20320	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
A4R43_20330	ENOG41082BM	Transcriptional regulator, arsr family
A4R43_20360	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
A4R43_20375	ENOG4105K7W	phage-related replication protein
A4R43_20400	ENOG4105BZU	Histidine kinase
A4R43_20405	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_20415	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_20425	ENOG4105DKW	ABC transporter
A4R43_20440	ENOG41066UZ	arginase EC 3.5.3.1
A4R43_20460	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A4R43_20485	ENOG41067TZ	transcriptional regulator, MarR family
A4R43_20490	ENOG4105EYF	MMPL domain protein
A4R43_20505	ENOG4105C2J	ABC transporter
A4R43_20510	ENOG4105CNN	ABC, transporter
A4R43_20520	ENOG4105CR4	methylisocitrate lyase
A4R43_20525	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A4R43_20530	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_20535	ENOG4108IXY	short-chain dehydrogenase reductase
A4R43_20540	ENOG4108JGH	Tetr family transcriptional regulator
A4R43_20555	ENOG4105CHU	acetyl-coa acetyltransferase
A4R43_20590	ENOG4108QER	Adenylate cyclase
A4R43_20615	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A4R43_20635	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_20645	ENOG4105C0H	protease
A4R43_20660	ENOG4105D7A	ATP-binding protein
A4R43_20665	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
A4R43_20720	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4R43_20745	ENOG4108MWI	inositol mono-phosphatase
A4R43_20750	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A4R43_20760	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A4R43_20780	ENOG4105C7B	Threonine dehydratase
A4R43_20790	ENOG4105EDW	glycosyl transferase, family 39
A4R43_20790	ENOG4105EDW	glycosyl transferase, family 39
A4R43_20805	ENOG4105KF0	sporulation and cell division protein, SsgA
A4R43_20820	ENOG4108KX4	response regulator
A4R43_20830	ENOG4105CUB	amino acid
A4R43_20875	ENOG4105FDK	ABC transporter
A4R43_20895	ENOG4108ZR3	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)
A4R43_20910	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_20950	ENOG4105GWZ	Roadblock lc7 family protein
A4R43_20955	ENOG4108TQ9	Histidine kinase
A4R43_20980	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A4R43_20985	ENOG4105K6V	RNA polymerase
A4R43_21000	ENOG4105GWZ	Roadblock lc7 family protein
A4R43_21010	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A4R43_21015	ENOG4105E2Y	ABC, transporter
A4R43_21020	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
A4R43_21025	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
A4R43_21045	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A4R43_21055	ENOG4105BZU	Histidine kinase
A4R43_21065	ENOG4108Q9V	regulatoR
A4R43_21075	ENOG4107TB5	TRANSCRIPTIONal
A4R43_21085	ENOG4107RN6	Monooxygenase
A4R43_21110	ENOG4105C5S	asparaginyl-tRNA synthetase
A4R43_21135	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4R43_21140	ENOG4105BZU	Histidine kinase
A4R43_21165	ENOG4105ECQ	AraC Family Transcriptional Regulator
A4R43_21185	ENOG4105DND	Transcriptional regulator
A4R43_21200	ENOG4105C6Z	Gluconate
A4R43_21260	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A4R43_21285	ENOG4105CHR	reductase
A4R43_21305	ENOG4105CSH	Transporter
A4R43_21310	ENOG4107RSM	transcriptional regulator
A4R43_21325	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4R43_21330	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_21335	ENOG41072TH	Protein of unknown function (DUF1479)
A4R43_21340	ENOG4105E2R	ROK family
A4R43_21395	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A4R43_21410	ENOG4105F44	Two component transcriptional regulator, winged helix family
A4R43_21415	ENOG4106F60	Histidine kinase
A4R43_21420	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A4R43_21430	ENOG4108UQS	dipeptidase
A4R43_21435	ENOG4105CPF	Cell wall formation (By similarity)
A4R43_21505	ENOG4107R13	MMPL domain protein
A4R43_21535	ENOG4108KC1	acyl-Coa dehydrogenase
A4R43_21540	ENOG4105KHC	sulfurtransferase
A4R43_21545	ENOG4105F27	Major Facilitator
A4R43_21565	ENOG4105CVJ	phosphoglycerate mutase
A4R43_21585	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_21595	ENOG4105ECP	epimerase
A4R43_21630	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A4R43_21690	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A4R43_21735	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A4R43_21775	ENOG4105ZXU	NLP P60 protein
A4R43_21790	ENOG4107UBR	Extracellular solute-binding protein family 3
A4R43_21795	ENOG4105CQ7	ATP-dependent helicase
A4R43_21805	ENOG4105CJ1	ABC, transporter
A4R43_21810	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
A4R43_21830	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_21835	ENOG4105BZU	Histidine kinase
A4R43_21860	ENOG4105CI2	imidazolone-5-propionate hydrolase
A4R43_21865	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A4R43_21875	ENOG4105CGP	Urocanate hydratase
A4R43_21880	ENOG4105C84	Histidine ammonia-lyase
A4R43_21905	ENOG4105VPX	protein, conserved in bacteria
A4R43_21945	ENOG4105ENE	Histidine kinase
A4R43_21950	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_21960	ENOG4105NTK	Transcriptional repressor Mpra
A4R43_21980	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A4R43_21985	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
A4R43_21990	ENOG4105CAK	Cell division ATP-binding protein ftsE
A4R43_21995	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A4R43_22015	ENOG4105D29	Helix-turn-helix type 11 domain protein
A4R43_22025	ENOG4105DJZ	UPF0182 protein
A4R43_22035	ENOG41063PX	domain protein
A4R43_22080	ENOG4105WBQ	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
A4R43_22115	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A4R43_22150	ENOG4105C5F	glutamine synthetase
A4R43_22180	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A4R43_22190	ENOG4105C4K	Nad synthetase
A4R43_22200	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A4R43_22215	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A4R43_22235	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4R43_22245	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A4R43_22255	ENOG4105CMT	Dihydroxyacetone kinase
A4R43_22275	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
A4R43_22305	ENOG4105EC2	ftsk spoIIIe
A4R43_22310	ENOG4105RFZ	Methylmalonyl-coA mutase
A4R43_22315	ENOG4105N14	lysine exporter protein LysE YggA
A4R43_22325	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A4R43_22345	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A4R43_22350	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A4R43_22355	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A4R43_22360	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A4R43_22365	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4R43_22370	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
A4R43_22375	ENOG41085Y2	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4R43_22380	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
A4R43_22390	ENOG4105ESV	Glycosyl transferase, family 4
A4R43_22400	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4R43_22410	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
A4R43_22415	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
A4R43_22425	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A4R43_22430	ENOG4105VFB	Binds the 23S rRNA (By similarity)
A4R43_22445	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
A4R43_22450	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A4R43_22460	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A4R43_22465	ENOG4105C75	arginyL-tRNA synthetase
A4R43_22485	ENOG4105C01	Dihydroxy-acid dehydratase
A4R43_22500	ENOG4105CHP	RNA polymerase
A4R43_22515	ENOG4108NIW	Leucine export protein LeuE
A4R43_22520	ENOG4105CPC	Aldo Keto reductase
A4R43_22550	ENOG41062B0	ABC transporter, permease
A4R43_22555	ENOG4107R9N	ABC transporter
A4R43_22560	ENOG4105C2J	ABC transporter
A4R43_22565	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
A4R43_22580	ENOG4105C9F	isomerase
A4R43_22590	ENOG4105F5R	ABC transporter
A4R43_22595	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
A4R43_22600	ENOG4105C2J	ABC transporter
A4R43_22635	ENOG4107ISF	Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol (DPA) to the arabinan domain to form terminal beta-(1- 2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids
A4R43_22680	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A4R43_22700	ENOG4108R85	Short chain dehydrogenase
A4R43_22735	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
A4R43_22740	ENOG4105Z85	coenzyme PQQ synthesis
A4R43_22750	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
A4R43_22755	ENOG4108FN7	Aldo keto reductase
A4R43_22770	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4R43_22795	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A4R43_22800	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4R43_22810	ENOG4108JPW	Aminotransferase
A4R43_22850	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4R43_22855	ENOG4105CHU	acetyl-coa acetyltransferase
A4R43_22870	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_22880	ENOG4105GFG	DUF218 domain
A4R43_22900	ENOG4105EMU	Dehydrogenase
A4R43_22915	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_22925	ENOG4107QX3	carboxylase
A4R43_22950	ENOG4105DWV	Homoserine O-trans-acetylase
A4R43_22965	ENOG4108K8K	Transcriptional regulator
A4R43_22985	ENOG4105DCF	alanine dehydrogenase
A4R43_22995	ENOG4105C57	major facilitator superfamily
A4R43_23010	ENOG4105BZ1	(ABC) transporter
A4R43_23015	ENOG410836F	Transposase
A4R43_23050	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A4R43_23055	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_23070	ENOG4105E90	ABC transporter
A4R43_23075	ENOG4105R40	Glycine betaine carnitine choline
A4R43_23080	ENOG4108IJ8	ABC transporter
A4R43_23105	ENOG4108ZM9	phosphoglycerate mutase
A4R43_23120	ENOG4105CBD	Diacylglycerol kinase
A4R43_23135	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
A4R43_23145	ENOG4105EMN	RNA polymerase sigma factor
A4R43_23150	ENOG4108Z66	YbaK ebsC protein
A4R43_23160	ENOG4108RAV	Conserved protein
A4R43_23165	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A4R43_23175	ENOG4105C26	Dehydrogenase
A4R43_23190	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A4R43_23205	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A4R43_23210	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
A4R43_23215	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A4R43_23220	ENOG4108MKR	lipoprotein lpqb
A4R43_23225	ENOG4105BZU	Histidine kinase
A4R43_23230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4R43_23235	ENOG4107HP6	Transcriptional regulator
A4R43_23255	ENOG4105CUB	amino acid
A4R43_23270	ENOG4105EIP	mannose-6-phosphate isomerase
A4R43_23280	ENOG4105W49	UPF0434 protein
A4R43_23300	ENOG4106BQ7	Glycosyl Transferase
A4R43_23305	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
A4R43_23310	ENOG4107XZ0	Peptidase M50
A4R43_23325	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
A4R43_23355	ENOG4107USK	Extracellular solute-binding protein, family 5
A4R43_23360	ENOG4105CI3	gtp-binding protein typa
A4R43_23370	ENOG4105C31	Tryptophanyl-tRNA synthetase
A4R43_23385	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4R43_23395	ENOG4105CJ1	ABC, transporter
A4R43_23405	ENOG4108UCS	ABC, transporter
A4R43_23420	ENOG410842T	Pterin carbinolamine dehydratase
A4R43_23450	ENOG4105C3G	gtp-binding protein
A4R43_23460	ENOG4105EYH	Exonuclease
A4R43_23465	ENOG4107RH8	nuclease SbcCD subunit D
A4R43_23480	ENOG4105CPC	Aldo Keto reductase
A4R43_23485	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A4R43_23495	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A4R43_23520	ENOG4105CAY	ferredoxin--nadp reductase
A4R43_23525	ENOG4105C9Q	fumarate hydratase class II
A4R43_23550	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_23555	ENOG4105CVA	phosphate
A4R43_23560	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
A4R43_23600	ENOG4107VMB	Beta-lactamase domain protein
A4R43_23610	ENOG4108IAB	Phoh family
A4R43_23630	ENOG41061H0	Monooxygenase
A4R43_23655	ENOG4105C7Z	Conserved Protein
A4R43_23665	ENOG4107S1Q	Phosphatase
A4R43_23675	ENOG4105T1M	mycothiol conjugate amidase mca
A4R43_23685	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A4R43_23695	ENOG4105EW9	transcriptional regulator AsnC family
A4R43_23700	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
A4R43_23705	ENOG4105C7B	Threonine dehydratase
A4R43_23745	ENOG4105CHU	acetyl-coa acetyltransferase
A4R43_23750	ENOG4105CUC	YeeE YedE family protein
A4R43_23770	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A4R43_23775	ENOG4108Z6Z	Transcriptional regulator
A4R43_23785	ENOG4105DRR	Transcriptional regulator, GntR family
A4R43_23790	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A4R43_23810	ENOG4105KVH	Transcriptional regulator
A4R43_23820	ENOG4105BZU	Histidine kinase
A4R43_23825	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_23840	ENOG4105CEP	NADH dehydrogenase
A4R43_23865	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_23870	ENOG4108JQ7	(ABC) transporter
A4R43_23875	ENOG4105C3U	ABC transporter
A4R43_23880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4R43_23885	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4R43_23890	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4R43_23920	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A4R43_23945	ENOG4105FQ6	thiopurine methyltransferase
A4R43_24010	ENOG4105BZU	Histidine kinase
A4R43_24015	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A4R43_24035	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A4R43_24040	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A4R43_24055	ENOG4107RCI	amp-dependent synthetase and ligase
A4R43_24060	ENOG4105C5H	ABC transporter
A4R43_24065	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A4R43_24070	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A4R43_24075	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A4R43_24080	ENOG4106839	domain protein
A4R43_24085	ENOG4105F8V	Hydrolase, tatD family
A4R43_24090	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A4R43_24125	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A4R43_24160	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A4R43_24165	ENOG4105E2D	ec 3.2.1.52
A4R43_24175	ENOG4108RPX	mosc domain containing protein
A4R43_24185	ENOG4105C26	Dehydrogenase
A4R43_24190	ENOG4107RR1	TRANSCRIPTIONal
A4R43_24215	ENOG4108IG5	Transcriptional regulator
A4R43_24220	ENOG4108RYK	Nad-dependent epimerase dehydratase
A4R43_24245	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4R43_24255	ENOG4105E7D	Protein of unknown function (DUF3375)
A4R43_24275	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_24285	ENOG4105CS2	ec 3.2.1.21
A4R43_24290	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A4R43_24295	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A4R43_24300	ENOG4105CNT	hydrolase family 2
A4R43_24305	ENOG4105DSG	hydrolase family 43
A4R43_24335	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
A4R43_24365	ENOG4105X7H	acyl-CoA dehydrogenase
A4R43_24370	ENOG4105CHR	reductase
A4R43_24470	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A4R43_24480	ENOG4105KBH	arsR family transcriptional regulator
A4R43_24495	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4R43_24500	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A4R43_24510	ENOG4107TDF	Formate hydrogenlyase subunit 4
A4R43_24520	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A4R43_24590	ENOG4105ECY	inositol monophosphatase
A4R43_24600	ENOG4107XR7	(6-pyruvoyl tetrahydrobiopterin) synthase
A4R43_24625	ENOG4105C4B	ABC transporter, permease
A4R43_24630	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A4R43_24640	ENOG4105ETX	regulatoR
A4R43_24685	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A4R43_24710	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
A4R43_24720	ENOG4105DU1	integral membrane protein, terc
A4R43_24735	ENOG4105DU1	integral membrane protein, terc
A4R43_24740	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A4R43_24745	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4R43_24770	ENOG4108TWJ	NADH dehydrogenase subunit 5
A4R43_24775	ENOG4105EVH	UPF0753 protein
A4R43_24785	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4R43_24790	ENOG4105C01	Dihydroxy-acid dehydratase
A4R43_24795	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A4R43_24800	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A4R43_24825	ENOG410836F	Transposase
A4R43_24875	ENOG4105CEC	DNA methylase N-4 N-6
A4R43_24950	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A4R43_24955	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
A4R43_24970	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A4R43_24975	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A4R43_24990	ENOG4105BZU	Histidine kinase
A4R43_24995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4R43_25035	ENOG4105C0H	protease
A4R43_25045	ENOG4105E98	transcriptional regulator DeoR family
A4R43_25055	ENOG4105ETX	regulatoR
A4R43_25060	ENOG4107ZT3	family UPF0126
A4R43_25065	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_25130	ENOG4105CIR	epoxide hydrolase
A4R43_25155	ENOG4105BZU	Histidine kinase
A4R43_25160	ENOG4107RBB	ABC transporter, permease
A4R43_25165	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4R43_25180	ENOG4105F44	Two component transcriptional regulator, winged helix family
A4R43_25185	ENOG4106F60	Histidine kinase
A4R43_25295	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
A4R43_25315	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_25325	ENOG4105EMU	Dehydrogenase
A4R43_25330	ENOG4108KQ5	Integrase catalytic subunit
A4R43_25345	ENOG4108PYU	two-component system response regulator
A4R43_25350	ENOG4105EB3	Histidine kinase
A4R43_25355	ENOG4107R13	MMPL domain protein
A4R43_25370	ENOG4105CPQ	Dehydrogenase
A4R43_25375	ENOG4105C85	amino acid
A4R43_25380	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
A4R43_25390	ENOG4105CPN	adenine deaminase
A4R43_25395	ENOG4105E39	Enoyl-CoA hydratase
A4R43_25400	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_25420	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_25425	ENOG4107QJT	sodium dicarboxylate symporter
A4R43_25450	ENOG4105E4F	Isochorismate synthase
A4R43_25520	ENOG4108IUX	(ABC) transporter
A4R43_25525	ENOG4105RHA	ABC transporter, permease
A4R43_25550	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_25560	ENOG4105CI2	imidazolone-5-propionate hydrolase
A4R43_25565	ENOG4107WI4	Aldose-1-epimerase
A4R43_25585	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A4R43_25605	ENOG4105MT3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
A4R43_25610	ENOG4107S16	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
A4R43_25620	ENOG4105CQM	Urea amidohydrolase subunit alpha
A4R43_25625	ENOG4105KI2	Urea amidohydrolase subunit beta
A4R43_25630	ENOG4108YZ9	Urea amidohydrolase subunit gamma
A4R43_25660	ENOG4105CJ1	ABC, transporter
A4R43_25670	ENOG4105BZU	Histidine kinase
A4R43_25675	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_25680	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A4R43_25685	ENOG4105ED2	Beta-lactamase
A4R43_25690	ENOG4108VJY	integral membrane protein
A4R43_25705	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4R43_25720	ENOG4105F44	Two component transcriptional regulator, winged helix family
A4R43_25725	ENOG4106F60	Histidine kinase
A4R43_25745	ENOG4105FCS	tRNA rRNA methyltransferase
A4R43_25770	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
A4R43_25780	ENOG4107SFI	Major Facilitator superfamily
A4R43_25790	ENOG4105C7N	Xanthine uracil vitamin C permease
A4R43_25805	ENOG41061H0	Monooxygenase
A4R43_25825	ENOG4108N0W	Major Facilitator superfamily
A4R43_25835	ENOG4105VEQ	Cold shock protein
A4R43_25845	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A4R43_25855	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
A4R43_25860	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_25865	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
A4R43_25870	ENOG410901E	Membrane
A4R43_25885	ENOG4105E2B	Taurine dioxygenase
A4R43_25905	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A4R43_25935	ENOG4108KQ5	Integrase catalytic subunit
A4R43_25960	ENOG4105GWZ	Roadblock lc7 family protein
A4R43_25975	ENOG4105GWZ	Roadblock lc7 family protein
A4R43_25990	ENOG4105EAD	ABC transporter
A4R43_25995	ENOG4105E5Q	amino acid AbC transporter
A4R43_26005	ENOG4106N3A	copper homeostasis protein cutc
A4R43_26025	ENOG4105CFI	type iii restriction protein res subunit
A4R43_26050	ENOG4107TCW	O-succinylbenzoate synthase
A4R43_26055	ENOG4105F87	Dehydratase
A4R43_26070	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A4R43_26080	ENOG4105VEQ	Cold shock protein
A4R43_26100	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
A4R43_26125	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A4R43_26140	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A4R43_26145	ENOG4105DWF	phosphomethylpyrimidine kinase
A4R43_26170	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A4R43_26175	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A4R43_26180	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A4R43_26185	ENOG4107Y5I	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A4R43_26200	ENOG4105C57	major facilitator superfamily
A4R43_26205	ENOG4105FDP	GntR family transcriptional regulator
A4R43_26210	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A4R43_26215	ENOG4105RD7	BadF BadG BcrA BcrD
A4R43_26225	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A4R43_26270	ENOG4105EV8	ectoine hydroxylase
A4R43_26275	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
A4R43_26285	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
A4R43_26295	ENOG4106MP8	UPF0754 membrane protein
A4R43_26305	ENOG4105FBA	Phospholipase Carboxylesterase
A4R43_26310	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
A4R43_26345	ENOG4105C01	Dihydroxy-acid dehydratase
A4R43_26355	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
A4R43_26365	ENOG4105C57	major facilitator superfamily
A4R43_26370	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
A4R43_26375	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
A4R43_26380	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
A4R43_26385	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
A4R43_26390	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
A4R43_26395	ENOG4105DXM	phenylacetic acid degradation protein
A4R43_26405	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A4R43_26420	ENOG4105XEA	Tetr family transcriptional regulator
A4R43_26440	ENOG4105K4P	CoA-binding domain protein
A4R43_26470	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_26480	ENOG4105EXN	Sulfate transport protein CysZ
A4R43_26490	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A4R43_26500	ENOG4107V2S	Transcriptional regulator
A4R43_26530	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
A4R43_26565	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A4R43_26570	ENOG41062GB	lipoprotein lpqE
A4R43_26575	ENOG4108VJ1	Transcriptional regulator (CarD family
A4R43_26580	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A4R43_26585	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A4R43_26595	ENOG4105C8N	cysteinyl-tRNA synthetase
A4R43_26605	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
A4R43_26625	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4R43_26655	ENOG4106MP8	UPF0754 membrane protein
A4R43_26670	ENOG4105E0A	ABC, transporter
A4R43_26690	ENOG4105CEN	a g-specific adenine glycosylase
A4R43_26700	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
A4R43_26715	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A4R43_26740	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4R43_26765	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
A4R43_26770	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A4R43_26795	ENOG4108Z6Z	Transcriptional regulator
A4R43_26815	ENOG4105EUJ	GTP cyclohydrolase i
A4R43_26820	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4R43_26850	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A4R43_26870	ENOG4105F0N	pyrophosphate phospho-hydrolase
A4R43_26895	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A4R43_26905	ENOG4105C8P	)-transporter
A4R43_26915	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A4R43_26950	ENOG4105C6E	dna polymerase iii
A4R43_26965	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A4R43_26990	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A4R43_26995	ENOG4108I5C	dEAD DEAH box helicase
A4R43_27045	ENOG4105D17	glycoside hydrolase, family 3 domain protein
A4R43_27050	ENOG4105EHZ	conserved protein UCP016719
A4R43_27055	ENOG4107S1E	Beta-lactamase
A4R43_27060	ENOG4106KNT	transcriptional regulator
A4R43_27065	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A4R43_27075	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A4R43_27085	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A4R43_27125	ENOG4105DUX	Transporter
A4R43_27130	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A4R43_27140	ENOG4105D74	hydrolase
A4R43_27155	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4R43_27225	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
A4R43_27270	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_27285	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A4R43_27305	ENOG4105CH6	catalase
A4R43_27325	ENOG4105E0Y	RtcB Protein
A4R43_27335	ENOG4105CFH	Aspartokinase
A4R43_27365	ENOG4105DTD	Dehydrogenase
A4R43_27375	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_27380	ENOG4108594	Permease of the drug metabolite transporter
A4R43_27390	ENOG4108JQ7	(ABC) transporter
A4R43_27395	ENOG4105C3U	ABC transporter
A4R43_27400	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4R43_27405	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4R43_27410	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4R43_27420	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A4R43_27425	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A4R43_27430	ENOG4108RU2	n-acetylmuramoyl-l-alanine amidase
A4R43_27435	ENOG4105KVH	Transcriptional regulator
A4R43_27440	ENOG410905P	Pyridoxamine 5-phosphate
A4R43_27455	ENOG4105DGI	Alkaline phosphatase
A4R43_27460	ENOG4105BZU	Histidine kinase
A4R43_27465	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4R43_27475	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_27515	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
A4R43_27555	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A4R43_27580	ENOG4108KXV	response regulator
A4R43_27585	ENOG41065SU	Two-component system sensor kinase
A4R43_27610	ENOG4105EC2	ftsk spoIIIe
A4R43_27630	ENOG4107JC6	Membrane
A4R43_27645	ENOG4108Z6B	deaminase
A4R43_27655	ENOG4105CH2	amidohydrolase
A4R43_27660	ENOG4105EVN	Prephenate dehydrogenase
A4R43_27685	ENOG4105CIG	ABC transporter
A4R43_27690	ENOG4105DIM	ABC transporter
A4R43_27700	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
A4R43_27705	ENOG4108XHQ	(2Fe-2S)-binding domain protein
A4R43_27720	ENOG4105BZM	domain protein
A4R43_27730	ENOG4108ZGX	Histidine kinase
A4R43_27770	ENOG4108FN7	Aldo keto reductase
A4R43_27845	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A4R43_27870	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A4R43_27900	ENOG4105FDF	Could be involved in DNA repair (By similarity)
A4R43_27920	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4R43_27925	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_27930	ENOG4108XG2	Histidine kinase
A4R43_27960	ENOG4105C7K	acetolactate synthase
A4R43_27970	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_27980	ENOG4107SM8	Adenylate Guanylate cyclase
A4R43_27985	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_28060	ENOG4108VC7	Protein of unknown function (DUF2587)
A4R43_28080	ENOG4108MKI	Glycosyl transferase, family 2
A4R43_28120	ENOG410602S	Transferase
A4R43_28130	ENOG4105IQ5	FAD linked oxidase domain protein
A4R43_28135	ENOG4108RG3	short-chain dehydrogenase reductase
A4R43_28160	ENOG4106YN8	Prenyltransferase
A4R43_28180	ENOG4105DYW	oxidoreductase
A4R43_28185	ENOG4108KP7	hydrolase
A4R43_28225	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_28230	ENOG4105CHR	reductase
A4R43_28235	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A4R43_28255	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A4R43_28300	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A4R43_28310	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4R43_28340	ENOG4105D5U	fad dependent oxidoreductase
A4R43_28355	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A4R43_28360	ENOG4108J2P	Alpha beta hydrolase fold
A4R43_28365	ENOG4105P3N	Membrane
A4R43_28370	ENOG4106032	Glutathionylspermidine synthase
A4R43_28420	ENOG4105ETU	transcriptional activator (TenA
A4R43_28425	ENOG4108TGR	phosphatase
A4R43_28435	ENOG4108UVJ	appr-1-p processing domain protein
A4R43_28440	ENOG4105CS9	pantothenic acid kinase
A4R43_28450	ENOG4105KBK	Zinc finger, swim domain protein
A4R43_28510	ENOG4108JJ9	ABC, transporter
A4R43_28515	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A4R43_28520	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A4R43_28580	ENOG4105CEU	Arginine dihydrolase
A4R43_28585	ENOG4107YEV	ferritin
A4R43_28595	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4R43_28625	ENOG4107QN1	sodium solute
A4R43_28690	ENOG4108M1A	Chitin-binding protein
A4R43_28710	ENOG4105IIU	Aminopeptidase
A4R43_28715	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A4R43_28760	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A4R43_28780	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_28785	ENOG4105BZU	Histidine kinase
A4R43_28830	ENOG4108RNG	Permease of the drug metabolite transporter
A4R43_28835	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A4R43_28870	ENOG4105E90	ABC transporter
A4R43_28875	ENOG4108IJ8	ABC transporter
A4R43_28880	ENOG4105E90	ABC transporter
A4R43_28885	ENOG4105C94	Transporter
A4R43_28975	ENOG4107TPY	serine threonine protein kinase
A4R43_28985	ENOG4105CI0	Citrate lyase
A4R43_29000	ENOG4105XT2	Transcriptional regulator
A4R43_29010	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4R43_29015	ENOG4105CHR	reductase
A4R43_29025	ENOG4108JQ7	(ABC) transporter
A4R43_29035	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4R43_29045	ENOG4105DEF	Extracellular solute-binding protein, family 5
A4R43_29050	ENOG4108QBF	Transcriptional regulator
A4R43_29090	ENOG4105TV9	FHA Domain-Containing protein
A4R43_29095	ENOG4105HZM	Fha domain containing protein
A4R43_29110	ENOG4105CJN	penicillin-binding protein
A4R43_29115	ENOG4107TPY	serine threonine protein kinase
A4R43_29120	ENOG4105D9P	serine threonine protein kinase
A4R43_29135	ENOG4108U4N	(sortase) family
A4R43_29140	ENOG4105XBB	septation inhibitor protein
A4R43_29285	ENOG4105ECY	inositol monophosphatase
A4R43_29330	ENOG4105K63	Thioredoxin
A4R43_29360	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A4R43_29435	ENOG4105CFG	Acts as a chaperone (By similarity)
A4R43_29440	ENOG410827T	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A4R43_29445	ENOG4105DVC	DnaJ domain protein
A4R43_29455	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4R43_29460	ENOG4105D0M	Protease HtpX homolog
A4R43_29475	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A4R43_29495	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A4R43_29515	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A4R43_29570	ENOG4105C2M	dna polymerase I
A4R43_29575	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A4R43_29585	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A4R43_29600	ENOG4105E6M	Sulphatase-modifying factor protein
A4R43_29610	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A4R43_29630	ENOG4106A3R	peptidase
A4R43_29760	ENOG4105D5G	Transposase
A4R43_29770	ENOG4105CPQ	Dehydrogenase
A4R43_29780	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_29785	ENOG4105MXW	flavin reductase domain protein, FMN-binding
A4R43_29790	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A4R43_29795	ENOG4105E39	Enoyl-CoA hydratase
A4R43_29805	ENOG4105D2B	acyl-CoA dehydrogenase
A4R43_29810	ENOG4108M8W	Monooxygenase
A4R43_29825	ENOG4108JGH	Tetr family transcriptional regulator
A4R43_29865	ENOG4105EYF	MMPL domain protein
A4R43_29940	ENOG4105C57	major facilitator superfamily
A4R43_29980	ENOG4107QX3	carboxylase
A4R43_30010	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_30030	ENOG4105EKQ	RNA-directed DNA polymerase
A4R43_30040	ENOG4108IPT	Naphthoate synthase
A4R43_30060	ENOG4105C26	Dehydrogenase
A4R43_30070	ENOG4108Z4U	Ferredoxin
A4R43_30075	ENOG4105CAY	ferredoxin--nadp reductase
A4R43_30080	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
A4R43_30090	ENOG4105BZU	Histidine kinase
A4R43_30095	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_30145	ENOG4105DHJ	ABC, transporter
A4R43_30175	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_30210	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_30235	ENOG4105D5G	Transposase
A4R43_30405	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4R43_30410	ENOG4105K7N	UPF0232 protein
A4R43_30415	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A4R43_30420	ENOG4108J5G	6-phosphogluconate dehydrogenase
A4R43_30425	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A4R43_30435	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A4R43_30440	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A4R43_30450	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A4R43_30455	ENOG4107QJE	Chromosome Partitioning Protein
A4R43_30465	ENOG4105CPF	Cell wall formation (By similarity)
A4R43_30480	ENOG4108E1C	hydrolase
A4R43_30485	ENOG4105C3M	thioredoxin reductase
A4R43_30490	ENOG4105C3M	thioredoxin reductase
A4R43_30515	ENOG4105DRP	amino acid AbC transporter
A4R43_30520	ENOG4105EAD	ABC transporter
A4R43_30545	ENOG4108XG2	Histidine kinase
A4R43_30600	ENOG41081DT	UPF0301 protein
A4R43_30615	ENOG4105C8T	Leucyl-tRNA synthetase
A4R43_30620	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A4R43_30640	ENOG4108RVA	ribokinase
A4R43_30650	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A4R43_30665	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_30690	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
A4R43_30755	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A4R43_30760	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A4R43_30770	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
A4R43_30805	ENOG4105E2R	ROK family
A4R43_30810	ENOG4105D9R	oxidoreductase
A4R43_30815	ENOG4105CI2	imidazolone-5-propionate hydrolase
A4R43_30820	ENOG4105BZ4	penicillin-binding protein
A4R43_30845	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
A4R43_30850	ENOG4105DXB	Major Facilitator superfamily
A4R43_30865	ENOG4107QWP	ABC-2 type transporter
A4R43_30885	ENOG4105EMU	Dehydrogenase
A4R43_30895	ENOG4105BZU	Histidine kinase
A4R43_30900	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_30905	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A4R43_30910	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_30920	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A4R43_30930	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A4R43_30950	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_30955	ENOG4105BZU	Histidine kinase
A4R43_30975	ENOG4107Z9D	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A4R43_30995	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A4R43_31055	ENOG410645S	MarR family Transcriptional regulator
A4R43_31065	ENOG4107TXC	Transcriptional regulator
A4R43_31070	ENOG4105HHS	UPF0256 protein
A4R43_31075	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
A4R43_31085	ENOG4105CHU	acetyl-coa acetyltransferase
A4R43_31090	ENOG4105CHR	reductase
A4R43_31095	ENOG4108F01	MaoC domain protein
A4R43_31100	ENOG4108R86	Transcriptional regulator
A4R43_31115	ENOG4105FS0	cytoplasmic membrane protein
A4R43_31125	ENOG4105BZ1	(ABC) transporter
A4R43_31135	ENOG4105CB5	ATP-dependent DNA helicase recG
A4R43_31140	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
A4R43_31145	ENOG4105CPP	Dehydrogenase, E1 component
A4R43_31155	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A4R43_31165	ENOG4106PMH	Extracellular solute-binding protein family 3
A4R43_31170	ENOG4105EAD	ABC transporter
A4R43_31190	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4R43_31195	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A4R43_31205	ENOG4105NAE	bifunctional deaminase-reductase domain protein
A4R43_31225	ENOG4105CSU	acyl-Coa dehydrogenase
A4R43_31230	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_31235	ENOG4108VCA	G U mismatch-specific DNA glycosylase
A4R43_31250	ENOG4105CGH	5'-nucleotidase
A4R43_31265	ENOG4105KK4	UPF0060 membrane protein
A4R43_31290	ENOG4105DHP	deoxycytidine triphosphate deaminase
A4R43_31300	ENOG4105K4I	Scp-like extracellular
A4R43_31305	ENOG4105E39	Enoyl-CoA hydratase
A4R43_31310	ENOG4105CSU	acyl-Coa dehydrogenase
A4R43_31315	ENOG4108SGK	Tetr family transcriptional regulator
A4R43_31350	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A4R43_31355	ENOG4105DF6	Fe-S oxidoreductase
A4R43_31395	ENOG4105CFG	Acts as a chaperone (By similarity)
A4R43_31400	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A4R43_31405	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A4R43_31410	ENOG4105KNI	merR family transcriptional Regulator
A4R43_31430	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4R43_31440	ENOG4108IXY	short-chain dehydrogenase reductase
A4R43_31460	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A4R43_31465	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A4R43_31480	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_31490	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
A4R43_31495	ENOG4105CNN	ABC, transporter
A4R43_31500	ENOG4105C2J	ABC transporter
A4R43_31510	ENOG4107Z1W	Fructose transport system kinase
A4R43_31515	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A4R43_31520	ENOG4105FDP	GntR family transcriptional regulator
A4R43_31525	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A4R43_31535	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
A4R43_31540	ENOG4108YYC	ycei family
A4R43_31555	ENOG41064MX	Tetr family transcriptional regulator
A4R43_31560	ENOG4105C57	major facilitator superfamily
A4R43_31575	ENOG4105CQB	FAD linked oxidase domain protein
A4R43_31580	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
A4R43_31590	ENOG4105CE4	GlcNAc 6-P deacetylase
A4R43_31615	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A4R43_31655	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A4R43_31665	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A4R43_31710	ENOG4108762	serine threonine protein kinase
A4R43_31725	ENOG4108FKH	Transglycosylase SLT domain
A4R43_31735	ENOG4105CHM	Aminotransferase
A4R43_31775	ENOG4105C83	adenylosuccinate lyase
A4R43_31785	ENOG4105EAB	amino acid AbC transporter
A4R43_31790	ENOG4105EAD	ABC transporter
A4R43_31795	ENOG4105CDA	abc transporter atp-binding protein
A4R43_31805	ENOG410635A	Membrane
A4R43_31845	ENOG410839H	phosphoribosylformylglycinamidine synthase
A4R43_31850	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A4R43_31855	ENOG4105BZ1	(ABC) transporter
A4R43_31860	ENOG4105BZ1	(ABC) transporter
A4R43_31865	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A4R43_31935	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A4R43_31940	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A4R43_31950	ENOG4108MRH	transcriptional regulatory protein
A4R43_31955	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
A4R43_31995	ENOG4105BZ1	(ABC) transporter
A4R43_32035	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
A4R43_32045	ENOG4107R7A	Allophanate hydrolase subunit 2
A4R43_32050	ENOG4105P4J	Allophanate hydrolase, subunit 1
A4R43_32055	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
A4R43_32060	ENOG4105PKJ	carbohydrate binding
A4R43_32065	ENOG4105KHC	sulfurtransferase
A4R43_32075	ENOG4106ITI	Glutaredoxin
A4R43_32085	ENOG4107NHD	transcriptional regulator
A4R43_32090	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A4R43_32110	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A4R43_32130	ENOG4108K8K	Transcriptional regulator
A4R43_32135	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
A4R43_32155	ENOG41067SE	Tetr family transcriptional regulator
A4R43_32180	ENOG4105EBR	Carboxylesterase
A4R43_32205	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4R43_32245	ENOG41064MX	Tetr family transcriptional regulator
A4R43_32250	ENOG41064MX	Tetr family transcriptional regulator
A4R43_32265	ENOG4107SQU	synthase
A4R43_32280	ENOG4108KGH	TRANSCRIPTIONal
A4R43_32290	ENOG4105BZU	Histidine kinase
A4R43_32300	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_32330	ENOG4105CEI	nitrite reductase
A4R43_32345	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A4R43_32385	ENOG4105CJA	serine threonine protein kinase
A4R43_32420	ENOG4105C7K	acetolactate synthase
A4R43_32430	ENOG4108ZGX	Histidine kinase
A4R43_32435	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_32445	ENOG4105CT1	(ABC) transporter
A4R43_32450	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
A4R43_32455	ENOG4105DTQ	mandelate racemase muconate lactonizing
A4R43_32460	ENOG4105C26	Dehydrogenase
A4R43_32465	ENOG4105C0A	alcohol dehydrogenase
A4R43_32470	ENOG4107Q25	Serine Threonine protein kinase
A4R43_32475	ENOG4107RN3	metallophosphoesterase
A4R43_32485	ENOG4105CSH	Transporter
A4R43_32495	ENOG4105NAF	rna polymerase sigma factor
A4R43_32510	ENOG4105VEQ	Cold shock protein
A4R43_32540	ENOG4108IJ0	Aspartate ammonia-lyase
A4R43_32610	ENOG4108VW9	Membrane
A4R43_32615	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_32635	ENOG4106BRA	Membrane
A4R43_32645	ENOG4105GRZ	Ycii-related protein
A4R43_32650	ENOG4105CHP	RNA polymerase
A4R43_32670	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A4R43_32675	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A4R43_32685	ENOG4105V9F	hemagglutinin
A4R43_32690	ENOG4105TT9	Protein of unknown function (DUF2516)
A4R43_32705	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A4R43_32715	ENOG4105CIY	formyltetrahydrofolate deformylase
A4R43_32735	ENOG4107R4N	Cell wall formation (By similarity)
A4R43_32750	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A4R43_32755	ENOG4108YZJ	Pfam:DUF2596
A4R43_32765	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A4R43_32785	ENOG4107S5I	aldo keto reductase
A4R43_32790	ENOG4105BZU	Histidine kinase
A4R43_32805	ENOG41063NU	Membrane
A4R43_32815	ENOG41062BK	proline dehydrogenase
A4R43_32825	ENOG4105II7	pyrroline-5-carboxylate reductase
A4R43_32855	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
A4R43_32870	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_32915	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
A4R43_32920	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A4R43_32925	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A4R43_32930	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A4R43_32955	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A4R43_32960	ENOG4108RH7	phosphoglycerate mutase
A4R43_32965	ENOG4107QX9	Thiol disulfide interChange protein
A4R43_32980	ENOG4105CRE	cytochrome C
A4R43_33000	ENOG4105F7P	transcriptional regulator AsnC family
A4R43_33035	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A4R43_33040	ENOG4105E7W	lamb ycsf family protein
A4R43_33055	ENOG4105ECY	inositol monophosphatase
A4R43_33065	ENOG4108MJN	Glycosyl Transferase
A4R43_33070	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_33085	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4R43_33090	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A4R43_33095	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4R43_33110	ENOG4108IEH	NADH dehydrogenase subunit g
A4R43_33115	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A4R43_33120	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4R43_33125	ENOG41087XN	oxidoreductase
A4R43_33130	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4R43_33145	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4R43_33235	ENOG4105DQU	oxidoreductase, subunit beta
A4R43_33240	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A4R43_33250	ENOG4108VVK	transcriptional Regulator, AsnC
A4R43_33255	ENOG4105CIK	Amidinotransferase
A4R43_33335	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4R43_33350	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4R43_33355	ENOG4107EF8	Glycosyl transferase (Group 1
A4R43_33365	ENOG4105CMR	udp-glucose 4-epimerase
A4R43_33370	ENOG4105D9R	oxidoreductase
A4R43_33390	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A4R43_33395	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
A4R43_33400	ENOG4108IG5	Transcriptional regulator
A4R43_33410	ENOG4108VPT	UPF0234 protein
A4R43_33445	ENOG41067SE	Tetr family transcriptional regulator
A4R43_33455	ENOG4108S01	response regulator
A4R43_33460	ENOG4105BZU	Histidine kinase
A4R43_33470	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A4R43_33485	ENOG4105BZU	Histidine kinase
A4R43_33500	ENOG4105WDJ	50S ribosomal protein L33
A4R43_33510	ENOG410900P	UPF0336 protein
A4R43_33530	ENOG4107U9B	transcriptional regulator
A4R43_33560	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A4R43_33565	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A4R43_33585	ENOG4108VZM	50s ribosomal protein L10
A4R43_33590	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A4R43_33655	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4R43_33660	ENOG4107XEY	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
A4R43_33680	ENOG4105BZU	Histidine kinase
A4R43_33685	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_33690	ENOG4108UQS	dipeptidase
A4R43_33740	ENOG4105E2R	ROK family
A4R43_33750	ENOG4105C2J	ABC transporter
A4R43_33755	ENOG4105CNN	ABC, transporter
A4R43_33780	ENOG4105DB3	bacteriochlorophyll chlorophyll a synthase
A4R43_33790	ENOG4105F8V	Hydrolase, tatD family
A4R43_33815	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A4R43_33820	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A4R43_33825	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A4R43_33840	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A4R43_33845	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A4R43_33850	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A4R43_33855	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A4R43_33860	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A4R43_33865	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A4R43_33870	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A4R43_33875	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A4R43_33880	ENOG41082SA	50s ribosomal protein l29
A4R43_33885	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A4R43_33890	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A4R43_33895	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A4R43_33900	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A4R43_33905	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A4R43_33910	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A4R43_33915	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A4R43_33920	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A4R43_33925	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A4R43_33930	ENOG410849U	50S ribosomal protein L30
A4R43_33935	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A4R43_33945	ENOG410829K	Lysine exporter protein (Lyse ygga)
A4R43_33955	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A4R43_33965	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A4R43_33970	ENOG41067V7	50S ribosomal protein L36
A4R43_33975	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A4R43_33985	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A4R43_33990	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A4R43_33995	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4R43_34000	ENOG4108ZT0	50S ribosomal protein l17
A4R43_34005	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A4R43_34050	ENOG4105EC2	ftsk spoIIIe
A4R43_34055	ENOG4105CFG	Acts as a chaperone (By similarity)
A4R43_34095	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A4R43_34100	ENOG4108UJD	30S ribosomal protein S9
A4R43_34105	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A4R43_34125	ENOG4107RCI	amp-dependent synthetase and ligase
A4R43_34155	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A4R43_34180	ENOG4105CPQ	Dehydrogenase
A4R43_34185	ENOG4107EDW	L-fucose operon activator
A4R43_34190	ENOG4105CPQ	Dehydrogenase
A4R43_34200	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A4R43_34205	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A4R43_34210	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
A4R43_34215	ENOG4108097	ATP-binding protein
A4R43_34220	ENOG4105I82	acetyl xylan esterase
A4R43_34225	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4R43_34230	ENOG4105D8K	carboxyl transferase
A4R43_34235	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_34245	ENOG4105C6F	GntR Family Transcriptional Regulator
A4R43_34250	ENOG4105CNA	YD repeat protein
A4R43_34270	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
A4R43_34275	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4R43_34285	ENOG4105DGI	Alkaline phosphatase
A4R43_34290	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A4R43_34295	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A4R43_34300	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
A4R43_34305	ENOG4108IND	Tetr family transcriptional regulator
A4R43_34310	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
A4R43_34340	ENOG4108VT4	
A4R43_34350	ENOG4107QVP	Dehydrogenase
A4R43_34375	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A4R43_34405	ENOG4107RSM	transcriptional regulator
A4R43_34465	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A4R43_34490	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A4R43_34500	ENOG4105K5X	acetyltransferase
A4R43_34530	ENOG4105C0B	DNA polymerase III (alpha subunit)
A4R43_34550	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A4R43_34560	ENOG4105F27	Major Facilitator
A4R43_34565	ENOG4105YVS	arsR family transcriptional regulator
A4R43_34570	ENOG4108RWP	Major Facilitator Superfamily protein
A4R43_34610	ENOG4105CGK	Exodeoxyribonuclease III
A4R43_34615	ENOG4108KQ5	Integrase catalytic subunit
A4R43_34635	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
A4R43_34645	ENOG4105C31	Tryptophanyl-tRNA synthetase
A4R43_34665	ENOG4107H3J	ribonuclease
A4R43_34670	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4R43_34675	ENOG4105DZ1	carboxypeptidase
A4R43_34685	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_34715	ENOG4105EWK	phytoene
A4R43_34720	ENOG4105ETE	Transcriptional regulator (LacI family
A4R43_34730	ENOG4105E33	succinate dehydrogenase
A4R43_34750	ENOG4105DIH	basic membrane
A4R43_34755	ENOG4108JQ9	ABC transporter
A4R43_34785	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A4R43_34790	ENOG4105E5T	Major Facilitator Superfamily
A4R43_34815	ENOG4105XYF	acetyltransferase
A4R43_34835	ENOG4105C26	Dehydrogenase
A4R43_34840	ENOG4105C26	Dehydrogenase
A4R43_34845	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A4R43_34880	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A4R43_34895	ENOG4105CPC	Aldo Keto reductase
A4R43_34900	ENOG4105CPC	Aldo Keto reductase
A4R43_34910	ENOG4107UWP	Major facilitator superfamily MFS_1
A4R43_34915	ENOG41064B9	(LipO)protein
A4R43_34940	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A4R43_34945	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
A4R43_34960	ENOG4107TPY	serine threonine protein kinase
A4R43_34985	ENOG4107RM1	amidohydrolase
A4R43_35010	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A4R43_35020	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
A4R43_35025	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_35035	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_35040	ENOG4105BZU	Histidine kinase
A4R43_35050	ENOG4108JIK	carboxylase
A4R43_35055	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
A4R43_35060	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
A4R43_35065	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
A4R43_35070	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A4R43_35080	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
A4R43_35095	ENOG4108JQ9	ABC transporter
A4R43_35115	ENOG4105CK2	sodium dicarboxylate symporter
A4R43_35120	ENOG4107WR6	Maf-like protein
A4R43_35125	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A4R43_35135	ENOG4105D8K	carboxyl transferase
A4R43_35155	ENOG4105CIR	epoxide hydrolase
A4R43_35175	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_35210	ENOG4105K4H	Nlp p60 protein
A4R43_35215	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A4R43_35225	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
A4R43_35255	ENOG4107TK4	histidinol-phosphate phosphatase
A4R43_35260	ENOG4105ETX	regulatoR
A4R43_35265	ENOG41065SU	Two-component system sensor kinase
A4R43_35315	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_35320	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_35335	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
A4R43_35345	ENOG4107RCI	amp-dependent synthetase and ligase
A4R43_35355	ENOG4105D8K	carboxyl transferase
A4R43_35360	ENOG4107YB1	Trehalose corynomycolyl transferase
A4R43_35395	ENOG4108SB3	DoxX Family
A4R43_35405	ENOG4107TB5	TRANSCRIPTIONal
A4R43_35410	ENOG4107TB5	TRANSCRIPTIONal
A4R43_35420	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A4R43_35425	ENOG4108TJN	glycosyl transferase group 1
A4R43_35440	ENOG4105E2K	Glycosyl transferase (Group 1
A4R43_35475	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
A4R43_35495	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
A4R43_35500	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
A4R43_35510	ENOG4108Z4U	Ferredoxin
A4R43_35560	ENOG4108URH	decarboxylase
A4R43_35570	ENOG4105C3Q	Glycosyl transferase, family 2
A4R43_35580	ENOG4108JJ9	ABC, transporter
A4R43_35585	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A4R43_35590	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A4R43_35615	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A4R43_35625	ENOG4108UKI	Enoyl-CoA hydratase
A4R43_35635	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A4R43_35640	ENOG4107RSM	transcriptional regulator
A4R43_35645	ENOG4105D94	Major Facilitator Superfamily
A4R43_35650	ENOG4107ZBN	O-methyltransferase
A4R43_35665	ENOG4105C0H	protease
A4R43_35670	ENOG4105UTW	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
A4R43_35685	ENOG4105CJW	magnesium transporter
A4R43_35700	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_35735	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
A4R43_35765	ENOG4105D7N	magnesium and cobalt transport protein CorA
A4R43_35795	ENOG4105DB7	PHP domain protein
A4R43_35800	ENOG41081FY	multiple antibiotic resistance (MarC)-related
A4R43_35825	ENOG4105C1J	atp-dependent rna helicase
A4R43_35860	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
A4R43_35870	ENOG4108YIQ	Alpha beta hydrolase
A4R43_35890	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A4R43_35905	ENOG4107QZF	nitrite reductase NADPH large subunit
A4R43_35910	ENOG4107QZF	nitrite reductase NADPH large subunit
A4R43_35935	ENOG4105D29	Helix-turn-helix type 11 domain protein
A4R43_35955	ENOG4105ENA	helicase
A4R43_35990	ENOG4108WQ6	secreted protein
A4R43_35995	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4R43_36030	ENOG4105C1V	Peptidase, M16
A4R43_36040	ENOG4105CVJ	phosphoglycerate mutase
A4R43_36090	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A4R43_36095	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A4R43_36200	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
A4R43_36230	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A4R43_36235	ENOG4105CRK	lysyL-tRNA synthetase
A4R43_36250	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A4R43_36255	ENOG4105EAC	phosphoserine phosphatase
A4R43_36300	ENOG4108RWI	nicotinamidase
A4R43_36305	ENOG4107RKP	Nicotinate phosphoribosyltransferase
A4R43_36310	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A4R43_36320	ENOG4105KXX	peptidase s58 dmpa
A4R43_36340	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A4R43_36345	ENOG4105NDT	Rhomboid family
A4R43_36360	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A4R43_36365	ENOG4108RQ5	Beta-lactamase domain-containing protein
A4R43_36375	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A4R43_36380	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A4R43_36405	ENOG4105KVH	Transcriptional regulator
A4R43_36455	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A4R43_36485	ENOG4105Y3U	Transglycosylase-associated protein
A4R43_36505	ENOG4105C0B	DNA polymerase III (alpha subunit)
A4R43_36510	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A4R43_36515	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A4R43_36525	ENOG4106YKD	Cytochrome p-450
A4R43_36555	ENOG4107RN6	Monooxygenase
A4R43_36560	ENOG4105DTA	methyltransferase
A4R43_36565	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4R43_36580	ENOG4105CSA	Coproporphyrinogen iii oxidase
A4R43_36590	ENOG4106UW1	Major Facilitator superfamily
A4R43_36815	ENOG4107Z3H	Transcriptional regulator, TetR family
A4R43_36820	ENOG4105EBR	Carboxylesterase
A4R43_36830	ENOG4107H3J	ribonuclease
A4R43_36850	ENOG4105DEN	Luciferase family
A4R43_36860	ENOG4105KVH	Transcriptional regulator
A4R43_36865	ENOG4107S5T	Carbohydrate kinase
A4R43_36870	ENOG4105IE8	Alpha-ketoglutarate permease
A4R43_36875	ENOG4105MVE	transcriptional regulator
A4R43_36880	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A4R43_36885	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
A4R43_36890	ENOG4105CMT	Dihydroxyacetone kinase
A4R43_36895	ENOG4107YVI	ribose 5-phosphate isomerase
A4R43_36900	ENOG4108M3J	Dehydrogenase
A4R43_36905	ENOG4105CMG	Carbohydrate kinase
A4R43_36910	ENOG4107W7X	Aldolase
A4R43_36915	ENOG4105CHR	reductase
A4R43_36920	ENOG4105YVS	arsR family transcriptional regulator
A4R43_36970	ENOG4105BZU	Histidine kinase
A4R43_36980	ENOG4105GR3	Histidine kinase
A4R43_36995	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A4R43_37005	ENOG4105CAQ	asparagine synthetase
A4R43_37010	ENOG4105D7W	serine acetyltransferase
A4R43_37035	ENOG4105BZU	Histidine kinase
A4R43_37045	ENOG4108S01	response regulator
A4R43_37055	ENOG4105E7U	AraC family transcriptional regulator
A4R43_37080	ENOG41068W2	Cytochrome p-450
A4R43_37115	ENOG4107QVI	Methyltransferase, type 11
A4R43_37135	ENOG4105C57	major facilitator superfamily
A4R43_37145	ENOG4105FDT	acyl-CoA dehydrogenase
A4R43_37155	ENOG4105EV4	Multidrug resistance protein mdtH
A4R43_37190	ENOG4105EXC	Acyl-transferase
A4R43_37205	ENOG4108KC1	acyl-Coa dehydrogenase
A4R43_37210	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_37215	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_37220	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
A4R43_37245	ENOG4105CAQ	asparagine synthetase
A4R43_37325	ENOG4105D8K	carboxyl transferase
A4R43_37340	ENOG4108V8F	Transcriptional regulator, MarR family
A4R43_37395	ENOG4105K5B	UPF0225 protein
A4R43_37430	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4R43_37435	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4R43_37445	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
A4R43_37450	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_37470	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A4R43_37480	ENOG4105F44	Two component transcriptional regulator, winged helix family
A4R43_37500	ENOG4105EB3	Histidine kinase
A4R43_37510	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4R43_37555	ENOG4108KDT	Molybdate metabolism regulator
A4R43_37560	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
A4R43_37565	ENOG4105RD5	
A4R43_37570	ENOG4105DEG	Vwa containing coxe family protein
A4R43_37575	ENOG410903U	zinc ion binding
A4R43_37615	ENOG4105C7H	Helicase, RecD TraA family
A4R43_37635	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
A4R43_37655	ENOG4105ETX	regulatoR
A4R43_37660	ENOG41062D9	Histidine kinase
A4R43_37675	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4R43_37680	ENOG4107RBB	ABC transporter, permease
A4R43_37710	ENOG4105F0K	SARP family transcriptional regulator
A4R43_37765	ENOG4108RG3	short-chain dehydrogenase reductase
A4R43_37790	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
A4R43_37800	ENOG4106H77	Inherit from COG: SH3 type 3 domain-containing protein
A4R43_37805	ENOG4105DGI	Alkaline phosphatase
A4R43_37810	ENOG4105VEQ	Cold shock protein
A4R43_37820	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A4R43_37825	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A4R43_37845	ENOG4108HUF	Transporter
A4R43_37850	ENOG4105BZ1	(ABC) transporter
A4R43_37860	ENOG4105DQ5	transport system permease protein
A4R43_37865	ENOG4105TVJ	transport system, permease
A4R43_37880	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A4R43_37890	ENOG4105CBC	glutamate synthase
A4R43_37895	ENOG4105CQB	FAD linked oxidase domain protein
A4R43_37910	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A4R43_37915	ENOG4105C8P	)-transporter
A4R43_37920	ENOG4106NZI	LysR family Transcriptional regulator
A4R43_37935	ENOG4105C1G	acyl-Coa dehydrogenase
A4R43_37945	ENOG4105CGU	Enoyl-CoA hydratase
A4R43_37950	ENOG4105DTD	Dehydrogenase
A4R43_37980	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
A4R43_38010	ENOG41061H0	Monooxygenase
A4R43_38015	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A4R43_38045	ENOG4107T8T	UPF0173 metal-dependent hydrolase
A4R43_38065	ENOG4105F95	Monooxygenase
A4R43_38100	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
A4R43_38110	ENOG4105CG3	alpha amylase, catalytic region
A4R43_38120	ENOG4105DCG	PHP domain protein
A4R43_38125	ENOG41062JF	Transcriptional regulator
A4R43_38130	ENOG4105EG6	Saccharopine dehydrogenase
A4R43_38150	ENOG4105ERH	Fumarylacetoacetate hydrolase
A4R43_38155	ENOG4105DIA	mandelate racemase muconate lactonizing
A4R43_38160	ENOG4105CHR	reductase
A4R43_38170	ENOG4105C2J	ABC transporter
A4R43_38175	ENOG4105CNN	ABC, transporter
A4R43_38180	ENOG4105JXH	GntR family transcriptional regulator
A4R43_38190	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
A4R43_38200	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_38245	ENOG4105DEI	Mannitol dehydrogenase
A4R43_38255	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_38260	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A4R43_38300	ENOG4105CUB	amino acid
A4R43_38330	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A4R43_38335	ENOG4107SM8	Adenylate Guanylate cyclase
A4R43_38345	ENOG4107S5I	aldo keto reductase
A4R43_38350	ENOG4105C5Q	Transcriptional regulator
A4R43_38370	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A4R43_38375	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A4R43_38380	ENOG4105CV8	reductase
A4R43_38385	ENOG4105F27	Major Facilitator
A4R43_38390	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
A4R43_38405	ENOG4105IK6	Terpene synthase metal-binding domain-containing protein
A4R43_38410	ENOG4105CIR	epoxide hydrolase
A4R43_38445	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
A4R43_38475	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4R43_38490	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
A4R43_38515	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A4R43_38540	ENOG4105D49	3-dehydroquinate synthase
A4R43_38555	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4R43_38560	ENOG410905P	Pyridoxamine 5-phosphate
A4R43_38565	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A4R43_38595	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_38620	ENOG4107RCI	amp-dependent synthetase and ligase
A4R43_38640	ENOG4105C3M	thioredoxin reductase
A4R43_38645	ENOG4107SK7	Sarcosine-dimethylglycine methyltransferase
A4R43_38660	ENOG4105NPE	arsR family transcriptional regulator
A4R43_38700	ENOG41067TZ	transcriptional regulator, MarR family
A4R43_38710	ENOG4107AQZ	Membrane
A4R43_38715	ENOG4105EGI	Transcriptional regulator
A4R43_38755	ENOG4108Z4X	TRANSCRIPTIONal
A4R43_38760	ENOG4105EXC	Acyl-transferase
A4R43_38785	ENOG4106UW1	Major Facilitator superfamily
A4R43_38800	ENOG4105VHU	single-stranded DNA-binding protein
A4R43_38815	ENOG4105C7I	Dehydrogenase
A4R43_38845	ENOG4105CG3	alpha amylase, catalytic region
A4R43_38855	ENOG4105D8X	mechanosensitive ion channel
A4R43_38875	ENOG4109057	
A4R43_38885	ENOG4105MC2	DSBA oxidoreductase
A4R43_38890	ENOG4105CSH	Transporter
A4R43_38925	ENOG4105K4H	Nlp p60 protein
A4R43_38930	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A4R43_39040	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A4R43_39050	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A4R43_39075	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A4R43_39110	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A4R43_39130	ENOG4108VQR	secreted hydrolase
A4R43_39140	ENOG4105C2J	ABC transporter
A4R43_39145	ENOG4105CNN	ABC, transporter
A4R43_39150	ENOG4105CNN	ABC, transporter
A4R43_39185	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A4R43_39205	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A4R43_39215	ENOG4105JXH	GntR family transcriptional regulator
A4R43_39230	ENOG4105CJ1	ABC, transporter
A4R43_39250	ENOG4105C03	ribonuclease
A4R43_39250	ENOG4105C03	ribonuclease
A4R43_39255	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A4R43_39260	ENOG4105K46	50S ribosomal protein l27
A4R43_39265	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A4R43_39270	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A4R43_39290	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4R43_39310	ENOG4105CSH	Transporter
A4R43_39315	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4R43_39315	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4R43_39320	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A4R43_39325	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A4R43_39330	ENOG4105CVJ	phosphoglycerate mutase
A4R43_39340	ENOG4105EPR	degv family
A4R43_39365	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A4R43_39370	ENOG4105KQC	Competence protein
A4R43_39390	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
A4R43_39430	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A4R43_39435	ENOG4105E2D	ec 3.2.1.52
A4R43_39450	ENOG4105EA8	2-Nitropropane dioxygenase
A4R43_39455	ENOG4105CUB	amino acid
A4R43_39460	ENOG4108MXF	Alpha Beta Hydrolase
A4R43_39465	ENOG4105CB2	alcohol dehydrogenase
A4R43_39480	ENOG41067XF	inhibitor
A4R43_39485	ENOG4108M7F	enoyl-CoA hydratase isomerase
A4R43_39510	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A4R43_39525	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_39530	ENOG4105BZU	Histidine kinase
A4R43_39535	ENOG4105EYF	MMPL domain protein
A4R43_39550	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4R43_39565	ENOG4105MHT	Transcriptional regulator, ARSR family
A4R43_39600	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
A4R43_39610	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
A4R43_39625	ENOG4105C8Y	Acetylornithine aminotransferase
A4R43_39630	ENOG4105C26	Dehydrogenase
A4R43_39635	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
A4R43_39640	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A4R43_39650	ENOG4105K59	histidine triad (HIT) protein
A4R43_39660	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
A4R43_39680	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A4R43_39705	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
A4R43_39710	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A4R43_39720	ENOG4108PJD	permease
A4R43_39760	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A4R43_39765	ENOG4108M15	ABC transporter
A4R43_39775	ENOG4105BZU	Histidine kinase
A4R43_39785	ENOG4108S01	response regulator
A4R43_39800	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A4R43_39820	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A4R43_39825	ENOG4105CT1	(ABC) transporter
A4R43_39830	ENOG4107RP9	extracellular solute-binding protein, family 3
A4R43_39835	ENOG4108KPJ	rna polymerase sigma factor
A4R43_39850	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A4R43_39880	ENOG4105D9P	serine threonine protein kinase
A4R43_39905	ENOG4105CNA	YD repeat protein
A4R43_39920	ENOG4105ERH	Fumarylacetoacetate hydrolase
A4R43_39930	ENOG41061H0	Monooxygenase
A4R43_39965	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A4R43_39970	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4R43_39990	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A4R43_39995	ENOG4107HP6	Transcriptional regulator
A4R43_40005	ENOG4108UHU	Aldolase
A4R43_40010	ENOG4105CXK	mandelate racemase muconate lactonizing
A4R43_40015	ENOG4105DJB	Major Facilitator Superfamily
A4R43_40035	ENOG4105EBR	Carboxylesterase
A4R43_40055	ENOG4105CHR	reductase
A4R43_40110	ENOG4105CDH	Citrulline--aspartate ligase
A4R43_40120	ENOG4108JGH	Tetr family transcriptional regulator
A4R43_40150	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A4R43_40155	ENOG4108WYP	Transcriptional regulator
A4R43_40160	ENOG4108UZX	fmn reductase
A4R43_40230	ENOG4105C22	threonyL-tRNA synthetase
A4R43_40245	ENOG4105CHP	RNA polymerase
A4R43_40270	ENOG4105EHG	Permease protein
A4R43_40275	ENOG4105E0A	ABC, transporter
A4R43_40295	ENOG4105F9F	transposase
A4R43_40320	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A4R43_40325	ENOG4105EJ2	Transcriptional regulator
A4R43_40350	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
A4R43_40425	ENOG4105C0A	alcohol dehydrogenase
A4R43_40510	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
A4R43_40515	ENOG41060NJ	transcriptional regulator
A4R43_40530	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A4R43_40565	ENOG4106T9R	serine protease
A4R43_40580	ENOG4105CT3	Monooxygenase
A4R43_40600	ENOG4107RSM	transcriptional regulator
A4R43_40660	ENOG4105DQE	DNA ligase
A4R43_40680	ENOG4105CAQ	asparagine synthetase
A4R43_40695	ENOG4105DKQ	ROK family
A4R43_40700	ENOG4105C93	Xylose Isomerase
A4R43_40745	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A4R43_40755	ENOG4105CEY	Amp-dependent synthetase and ligase
A4R43_40760	ENOG410846T	CoA-transferase family III
A4R43_40770	ENOG4108ES0	acetoacetyl-CoA synthetase
A4R43_40805	ENOG4108KB0	deacetylase
A4R43_40815	ENOG4105EP9	oxidoreductase
A4R43_40825	ENOG4107EG8	signal transduction protein with EFhand domain
A4R43_40830	ENOG4107QQG	Dehydrogenase
A4R43_40860	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
A4R43_40865	ENOG4107SCK	Monooxygenase
A4R43_40915	ENOG4105C3R	Methionine synthase
A4R43_40930	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A4R43_40950	ENOG4105CPC	Aldo Keto reductase
A4R43_40965	ENOG4108RF4	Tetr family transcriptional regulator
A4R43_40970	ENOG4105ECR	NmrA family
A4R43_40975	ENOG4105KVH	Transcriptional regulator
A4R43_40985	ENOG4105WH1	Two component transcriptional regulator luxr family
A4R43_41010	ENOG41063SB	peptidase
A4R43_41015	ENOG4105W1N	transcriptional regulator
A4R43_41030	ENOG4105C92	Aminotransferase class V
A4R43_41045	ENOG4107Z1I	Required for maturation of 30S ribosomal subunits (By similarity)
A4R43_41060	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A4R43_41070	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A4R43_41090	ENOG4105SFS	phosphoesterase RecJ domain protein
A4R43_41130	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A4R43_41150	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A4R43_41155	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A4R43_41160	ENOG4105C1V	Peptidase, M16
A4R43_41165	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A4R43_41190	ENOG4105T0Z	Conserved Protein
A4R43_41195	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4R43_41200	ENOG4108YYH	Nadph-dependent fmn reductase
A4R43_41205	ENOG4107SM8	Adenylate Guanylate cyclase
A4R43_41235	ENOG4105D9P	serine threonine protein kinase
A4R43_41240	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4R43_41245	ENOG4105CN5	Metallo-Beta-Lactamase
A4R43_41270	ENOG4107QZI	cell division protein FtsK
A4R43_41295	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A4R43_41305	ENOG4105CEV	competence damage-inducible protein
A4R43_41310	ENOG4105WBV	Transcriptional regulator
A4R43_41330	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A4R43_41335	ENOG4108YYQ	gCN5-related N-acetyltransferase
A4R43_41340	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A4R43_41345	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
A4R43_41350	ENOG4105D1F	ATP-binding protein
A4R43_41360	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A4R43_41380	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4R43_41405	ENOG4108V6E	Cell division protein mraZ
A4R43_41410	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A4R43_41420	ENOG4105CJN	penicillin-binding protein
A4R43_41435	ENOG4107R33	ppx gppa phosphatase
A4R43_41480	ENOG4105CTK	cobaltochelatase, cobn subunit
A4R43_41485	ENOG4105VZ8	Transcriptional regulator
A4R43_41500	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
A4R43_41505	ENOG41081F0	Precorrin-8x methylmutase
A4R43_41515	ENOG4105J1Z	Arabinosyltransferase
A4R43_41535	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
A4R43_41550	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A4R43_41560	ENOG410813T	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A4R43_41570	ENOG4108YZT	Adenosylcobinamide kinase
A4R43_41575	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A4R43_41580	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A4R43_41605	ENOG4105EEI	dihydropteroate synthase
A4R43_41630	ENOG4108XM1	transcriptional regulator AsnC family
A4R43_41645	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
A4R43_41665	ENOG4105DXX	methyltransferase
A4R43_41670	ENOG4105EHG	Permease protein
A4R43_41685	ENOG4105C6T	cysteine synthase
A4R43_41700	ENOG4105BZ1	(ABC) transporter
A4R43_41705	ENOG41068WN	
A4R43_41720	ENOG4105CWX	Alpha-1,2-mannosidase
A4R43_41730	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4R43_41745	ENOG4105EMU	Dehydrogenase
A4R43_41750	ENOG4106Z86	ATP-nad acox kinase
A4R43_41755	ENOG4107R0V	Pyruvate dehydrogenase
A4R43_41765	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
A4R43_41775	ENOG4107RR1	TRANSCRIPTIONal
A4R43_41830	ENOG4105EDW	glycosyl transferase, family 39